IMP: Integrative Multi-species Prediction

Danio rerio

0 known processes

cct5

chaperonin containing TCP1, subunit 5 (epsilon)

(Aliases: wu:fb54h08)

ZFIN: ZDB-GENE-030131-977
Ensembl: ENSDARG00000045399
Entrez: 322258
UniProtKB: Q6NVI6

Process Predictions
Disease Predictions

cct5 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
larval development	GO:0002164	2	0.951	Worm
embryo development ending in birth or egg hatching	GO:0009792	271	0.946	Worm
single fertilization	GO:0007338	3	0.890	Mouse
cellular macromolecule biosynthetic process	GO:0034645	224	0.740
regulation of cellular biosynthetic process	GO:0031326	245	0.695
spindle assembly involved in mitosis	GO:0090307	1	0.684	Fly
biosynthetic process	GO:0009058	294	0.672
cellular biosynthetic process	GO:0044249	286	0.610
organic substance biosynthetic process	GO:1901576	289	0.604
toxin transport	GO:1901998	2	0.592	Mouse
cellular macromolecule metabolic process	GO:0044260	391	0.582	Yeast
reproduction	GO:0000003	40	0.556	Mouse Worm
fertilization	GO:0009566	3	0.510	Mouse
cellular protein catabolic process	GO:0044257	4	0.505
cell recognition	GO:0008037	19	0.480	Mouse
cellular protein metabolic process	GO:0044267	129	0.467	Yeast
reproductive process	GO:0022414	40	0.460	Mouse Worm
regulation of biosynthetic process	GO:0009889	250	0.442
response to stress	GO:0006950	263	0.440
macromolecule biosynthetic process	GO:0009059	227	0.414
locomotion	GO:0040011	313	0.397	Worm
spindle assembly	GO:0051225	2	0.349	Fly
regulation of primary metabolic process	GO:0080090	311	0.337
organelle organization	GO:0006996	227	0.331	Fly
single organism reproductive process	GO:0044702	40	0.322	Mouse Worm
nucleoside monophosphate catabolic process	GO:0009125	4	0.303
cytokinesis	GO:0000910	3	0.297
protein metabolic process	GO:0019538	183	0.286	Yeast
modification dependent protein catabolic process	GO:0019941	3	0.282
regulation of gene expression	GO:0010468	265	0.263
sexual reproduction	GO:0019953	36	0.257	Mouse
protein stabilization	GO:0050821	2	0.247
programmed cell death	GO:0012501	119	0.247	Worm
ribonucleoside monophosphate catabolic process	GO:0009158	4	0.246
microtubule cytoskeleton organization involved in mitosis	GO:1902850	1	0.246	Fly
nucleobase containing compound biosynthetic process	GO:0034654	205	0.245
gene expression	GO:0010467	252	0.244
nucleobase containing compound metabolic process	GO:0006139	274	0.238
aging	GO:0007568	2	0.225
cell cell recognition	GO:0009988	1	0.224	Mouse
regulation of apoptotic process	GO:0042981	98	0.216
regulation of metabolic process	GO:0019222	359	0.215
positive regulation of biological process	GO:0048518	253	0.213
purine nucleoside monophosphate catabolic process	GO:0009128	4	0.202
organic cyclic compound metabolic process	GO:1901360	301	0.201
regulation of macromolecule biosynthetic process	GO:0010556	225	0.197
translation	GO:0006412	5	0.193
purine ribonucleoside monophosphate catabolic process	GO:0009169	4	0.192
protein complex assembly	GO:0006461	30	0.189	Fly
regulation of cellular metabolic process	GO:0031323	320	0.188
multi organism process	GO:0051704	134	0.184	Human Mouse
embryonic organ morphogenesis	GO:0048562	274	0.179
nucleobase containing small molecule metabolic process	GO:0055086	32	0.176
cellular aromatic compound metabolic process	GO:0006725	295	0.174
chordate embryonic development	GO:0043009	271	0.170
developmental process involved in reproduction	GO:0003006	27	0.158	Worm
heterocycle biosynthetic process	GO:0018130	215	0.157
single organism organelle organization	GO:1902589	199	0.157	Fly
protein complex subunit organization	GO:0071822	46	0.156	Fly
proteolysis involved in cellular protein catabolic process	GO:0051603	3	0.154
small molecule metabolic process	GO:0044281	77	0.154
regulation of nitrogen compound metabolic process	GO:0051171	251	0.151
apoptotic process	GO:0006915	116	0.150	Worm
cytoskeleton organization	GO:0007010	96	0.149	Fly
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	2	0.148
establishment of localization	GO:0051234	244	0.141	Mouse Worm
rna biosynthetic process	GO:0032774	181	0.132
aromatic compound biosynthetic process	GO:0019438	217	0.128
mitotic dna damage checkpoint	GO:0044773	4	0.127
nucleic acid templated transcription	GO:0097659	181	0.125
reproductive structure development	GO:0048608	5	0.119	Worm
organic cyclic compound biosynthetic process	GO:1901362	223	0.119
negative regulation of biological process	GO:0048519	304	0.119
rna metabolic process	GO:0016070	219	0.118
heterocycle metabolic process	GO:0046483	290	0.117
cell cycle	GO:0007049	93	0.115	Fly
cellular component movement	GO:0006928	335	0.115
regulation of macromolecule metabolic process	GO:0060255	317	0.112
sensory organ development	GO:0007423	393	0.112
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.110
positive regulation of protein complex assembly	GO:0031334	2	0.108
negative regulation of cellular process	GO:0048523	283	0.107
nucleic acid metabolic process	GO:0090304	244	0.106
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	10	0.106
response to external stimulus	GO:0009605	264	0.105	Human
organonitrogen compound metabolic process	GO:1901564	74	0.104
positive regulation of biosynthetic process	GO:0009891	68	0.104
embryonic organ development	GO:0048568	381	0.103
modification dependent macromolecule catabolic process	GO:0043632	3	0.101
cellular response to stress	GO:0033554	62	0.100
positive regulation of macromolecule metabolic process	GO:0010604	93	0.099
single organism metabolic process	GO:0044710	217	0.099
cellular component assembly	GO:0022607	170	0.099	Fly
carbohydrate derivative metabolic process	GO:1901135	61	0.098
gamete generation	GO:0007276	33	0.097
positive regulation of cellular biosynthetic process	GO:0031328	68	0.094
response to topologically incorrect protein	GO:0035966	2	0.094
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.092
positive regulation of cellular metabolic process	GO:0031325	94	0.092
embryonic skeletal system morphogenesis	GO:0048704	93	0.090
regulation of transcription dna templated	GO:0006355	213	0.089
nitrogen compound metabolic process	GO:0006807	319	0.085
mitotic spindle organization	GO:0007052	5	0.083	Fly
purine containing compound metabolic process	GO:0072521	29	0.083
nucleotide metabolic process	GO:0009117	28	0.080
cell morphogenesis	GO:0000902	289	0.080
multi organism reproductive process	GO:0044703	36	0.080	Mouse
positive regulation of translation	GO:0045727	1	0.079
protein complex biogenesis	GO:0070271	30	0.076	Fly
proteasomal protein catabolic process	GO:0010498	2	0.073
single organism transport	GO:0044765	206	0.070
purine nucleotide metabolic process	GO:0006163	27	0.069
atp catabolic process	GO:0006200	4	0.069
positive regulation of catabolic process	GO:0009896	4	0.068
regulation of programmed cell death	GO:0043067	101	0.067
post embryonic development	GO:0009791	7	0.067	Worm
negative regulation of gene expression	GO:0010629	65	0.067
regulation of multicellular organismal process	GO:0051239	277	0.067
transport	GO:0006810	220	0.065	Mouse Worm
cell motility	GO:0048870	244	0.064
cellular macromolecular complex assembly	GO:0034622	24	0.064
positive regulation of cellular component biogenesis	GO:0044089	3	0.064
nuclear transport	GO:0051169	4	0.063
regulation of protein metabolic process	GO:0051246	56	0.063
regulation of cellular macromolecule biosynthetic process	GO:2000112	222	0.062
multicellular organismal reproductive process	GO:0048609	35	0.061
positive regulation of metabolic process	GO:0009893	108	0.058
angiogenesis	GO:0001525	158	0.057
regulation of multicellular organism growth	GO:0040014	4	0.057
response to chemical	GO:0042221	320	0.056
death	GO:0016265	121	0.056	Worm
positive regulation of cellular catabolic process	GO:0031331	3	0.056
mitochondrion organization	GO:0007005	4	0.055
cellular component biogenesis	GO:0044085	178	0.055	Fly
mitotic cell cycle process	GO:1903047	48	0.054	Fly
cytoskeleton dependent cytokinesis	GO:0061640	3	0.052
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.051
growth	GO:0040007	174	0.051
phagocytosis	GO:0006909	3	0.049
regulation of cell death	GO:0010941	103	0.049
translational initiation	GO:0006413	3	0.048
phosphate containing compound metabolic process	GO:0006796	108	0.048
regulation of protein binding	GO:0043393	3	0.048
embryonic cranial skeleton morphogenesis	GO:0048701	90	0.048
transcription from rna polymerase ii promoter	GO:0006366	80	0.047
embryonic skeletal system development	GO:0048706	97	0.047
cellular localization	GO:0051641	97	0.046
posttranscriptional regulation of gene expression	GO:0010608	14	0.046
macromolecule modification	GO:0043412	111	0.046
germ cell development	GO:0007281	22	0.046
ribonucleotide metabolic process	GO:0009259	27	0.045
cellular component disassembly	GO:0022411	1	0.044
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	1	0.044
cell migration	GO:0016477	237	0.044
cell part morphogenesis	GO:0032990	246	0.044
negative regulation of macromolecule metabolic process	GO:0010605	76	0.043
head development	GO:0060322	303	0.042
rna localization	GO:0006403	4	0.042
multicellular organism growth	GO:0035264	4	0.042
fin regeneration	GO:0031101	51	0.042
multicellular organism reproduction	GO:0032504	35	0.042
mitotic dna integrity checkpoint	GO:0044774	4	0.041
regulation of binding	GO:0051098	3	0.041
cellular nitrogen compound metabolic process	GO:0034641	290	0.041
eye development	GO:0001654	277	0.041
response to alkaloid	GO:0043279	2	0.040
central nervous system development	GO:0007417	387	0.040
single organism localization	GO:1902578	225	0.040
cellular response to nutrient levels	GO:0031669	2	0.040
regulation of rna metabolic process	GO:0051252	224	0.038
cellular response to extracellular stimulus	GO:0031668	2	0.037
gtp catabolic process	GO:0006184	2	0.037
gtp metabolic process	GO:0046039	4	0.037
endocytosis	GO:0006897	16	0.036	Worm
cell cycle process	GO:0022402	53	0.035	Fly
body morphogenesis	GO:0010171	16	0.035
regulation of nucleotide catabolic process	GO:0030811	2	0.034
glycosyl compound metabolic process	GO:1901657	11	0.034
regulation of purine nucleotide catabolic process	GO:0033121	2	0.034
proteolysis	GO:0006508	38	0.034
negative regulation of macromolecule biosynthetic process	GO:0010558	48	0.034
regulation of response to stimulus	GO:0048583	269	0.034
oxoacid metabolic process	GO:0043436	31	0.033
tissue regeneration	GO:0042246	74	0.033
purine ribonucleotide metabolic process	GO:0009150	27	0.033
microtubule based process	GO:0007017	60	0.032	Fly
mitochondrial transport	GO:0006839	2	0.032
establishment of protein localization to organelle	GO:0072594	4	0.032
cellular response to external stimulus	GO:0071496	2	0.032
regulation of protein catabolic process	GO:0042176	1	0.031
purine ribonucleoside triphosphate metabolic process	GO:0009205	9	0.031
regulation of nucleic acid templated transcription	GO:1903506	213	0.031
negative regulation of protein phosphorylation	GO:0001933	4	0.031
response to organic substance	GO:0010033	153	0.030
cellular response to chemical stimulus	GO:0070887	157	0.030
transcription dna templated	GO:0006351	181	0.030
positive regulation of cellular process	GO:0048522	201	0.030
regulation of nucleoside metabolic process	GO:0009118	2	0.030
macromolecular complex subunit organization	GO:0043933	74	0.030	Fly
regulation of rna biosynthetic process	GO:2001141	213	0.030
cellular response to topologically incorrect protein	GO:0035967	2	0.029
organophosphate metabolic process	GO:0019637	37	0.029
cellular protein complex assembly	GO:0043623	19	0.028
cellular response to starvation	GO:0009267	1	0.028
positive regulation of purine nucleotide catabolic process	GO:0033123	1	0.028
neuron projection morphogenesis	GO:0048812	161	0.027
response to antibiotic	GO:0046677	1	0.027
catabolic process	GO:0009056	32	0.027
atp metabolic process	GO:0046034	5	0.027
symbiosis encompassing mutualism through parasitism	GO:0044403	4	0.027
organelle assembly	GO:0070925	110	0.027	Fly
nucleoside phosphate metabolic process	GO:0006753	28	0.027
regulation of anatomical structure morphogenesis	GO:0022603	130	0.027
skeletal system development	GO:0001501	181	0.026
maintenance of location	GO:0051235	4	0.026
wound healing	GO:0042060	90	0.026
ribose phosphate metabolic process	GO:0019693	27	0.026
positive regulation of nucleotide catabolic process	GO:0030813	1	0.025
oocyte anterior posterior axis specification	GO:0007314	4	0.025
spermatid development	GO:0007286	2	0.025
response to unfolded protein	GO:0006986	2	0.025
organic substance catabolic process	GO:1901575	28	0.025
gene silencing by rna	GO:0031047	4	0.025
negative regulation of metabolic process	GO:0009892	86	0.025
protein acetylation	GO:0006473	2	0.025
negative regulation of cellular metabolic process	GO:0031324	77	0.024
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	48	0.024
blood vessel development	GO:0001568	246	0.024
zymogen activation	GO:0031638	3	0.024
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.023
regulation of signaling	GO:0023051	235	0.023
mrna polyadenylation	GO:0006378	2	0.023
response to abiotic stimulus	GO:0009628	122	0.023
cell death	GO:0008219	121	0.023	Worm
aromatic compound catabolic process	GO:0019439	15	0.023
defense response	GO:0006952	47	0.023
organic substance transport	GO:0071702	58	0.023
protein modification process	GO:0036211	100	0.023
organic acid metabolic process	GO:0006082	31	0.023
meiotic cell cycle process	GO:1903046	3	0.023
cellular catabolic process	GO:0044248	27	0.023
positive regulation of gene expression	GO:0010628	71	0.022
regeneration	GO:0031099	91	0.022
nucleoside metabolic process	GO:0009116	11	0.022
protein polymerization	GO:0051258	4	0.022
response to monosaccharide	GO:0034284	3	0.022
mitotic g2 dna damage checkpoint	GO:0007095	3	0.022
regulation of gtp catabolic process	GO:0033124	2	0.022
behavior	GO:0007610	74	0.022
regulation of molecular function	GO:0065009	70	0.022
cellular amino acid metabolic process	GO:0006520	7	0.021
cell projection organization	GO:0030030	284	0.021
positive regulation of gtp catabolic process	GO:0033126	1	0.021
guanosine containing compound catabolic process	GO:1901069	2	0.021
protein secretion	GO:0009306	1	0.021
wnt signaling pathway	GO:0016055	80	0.021
carboxylic acid metabolic process	GO:0019752	22	0.020
purine ribonucleoside triphosphate catabolic process	GO:0009207	6	0.020
positive regulation of notch signaling pathway	GO:0045747	3	0.020
regulation of translation	GO:0006417	3	0.020
negative regulation of apoptotic process	GO:0043066	55	0.020
morphogenesis of an epithelium	GO:0002009	333	0.020
glial cell differentiation	GO:0010001	42	0.020
skeletal system morphogenesis	GO:0048705	102	0.020
macromolecule localization	GO:0033036	54	0.020
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.020
mitotic cell cycle	GO:0000278	64	0.020	Fly
ribonucleoside metabolic process	GO:0009119	11	0.019
interspecies interaction between organisms	GO:0044419	4	0.019
positive regulation of gtpase activity	GO:0043547	1	0.019
cell projection morphogenesis	GO:0048858	244	0.019
muscle organ development	GO:0007517	101	0.019
response to wounding	GO:0009611	116	0.019
cell surface receptor signaling pathway	GO:0007166	325	0.019
mitotic nuclear division	GO:0007067	18	0.019	Fly
nuclear export	GO:0051168	1	0.019
meiotic spindle organization	GO:0000212	1	0.018
digestive tract morphogenesis	GO:0048546	231	0.018
embryonic digestive tract development	GO:0048566	4	0.018
negative regulation of cell death	GO:0060548	60	0.018
neuron differentiation	GO:0030182	353	0.018
digestive system development	GO:0055123	289	0.018
gene silencing	GO:0016458	4	0.018
tube morphogenesis	GO:0035239	349	0.018
pigmentation	GO:0043473	85	0.018
ubiquitin dependent protein catabolic process	GO:0006511	3	0.018
post embryonic morphogenesis	GO:0009886	4	0.017
regulation of signal transduction	GO:0009966	225	0.017
microtubule polymerization	GO:0046785	2	0.017
dna templated transcription initiation	GO:0006352	1	0.017
carbohydrate homeostasis	GO:0033500	1	0.017
regulation of cell cycle	GO:0051726	52	0.017
regulation of gtpase activity	GO:0043087	2	0.017
regulation of biological quality	GO:0065008	263	0.017
spermatid differentiation	GO:0048515	2	0.017
g2 dna damage checkpoint	GO:0031572	3	0.016
purine ribonucleoside metabolic process	GO:0046128	10	0.016
camera type eye development	GO:0043010	222	0.016
regulation of developmental process	GO:0050793	247	0.016
brain development	GO:0007420	293	0.016
positive regulation of apoptotic signaling pathway	GO:2001235	1	0.016
pore complex assembly	GO:0046931	2	0.016
regulation of cellular amino acid metabolic process	GO:0006521	0	0.016
single organism biosynthetic process	GO:0044711	71	0.016
nucleic acid transport	GO:0050657	2	0.016
negative regulation of cellular biosynthetic process	GO:0031327	55	0.016
phosphorus metabolic process	GO:0006793	109	0.016
regulation of multicellular organismal development	GO:2000026	223	0.015
development of primary sexual characteristics	GO:0045137	5	0.015	Worm
protein homooligomerization	GO:0051260	3	0.015
negative regulation of biosynthetic process	GO:0009890	55	0.015
guanosine containing compound metabolic process	GO:1901068	4	0.015
determination of bilateral symmetry	GO:0009855	204	0.015
cell cycle g1 s phase transition	GO:0044843	1	0.014
protein import	GO:0017038	3	0.014
nucleocytoplasmic transport	GO:0006913	4	0.014
homeostatic process	GO:0042592	142	0.014
regulation of cellular amine metabolic process	GO:0033238	0	0.014
regulation of cell communication	GO:0010646	232	0.014
protein localization to plasma membrane	GO:0072659	1	0.014
heterocycle catabolic process	GO:0046700	15	0.014
positive regulation of cysteine type endopeptidase activity	GO:2001056	10	0.013
cellular response to unfolded protein	GO:0034620	2	0.013
pole plasm assembly	GO:0007315	4	0.013
regulation of cellular protein catabolic process	GO:1903362	1	0.013
regulation of cell cycle process	GO:0010564	20	0.013
endoplasmic reticulum unfolded protein response	GO:0030968	2	0.013
meiotic nuclear division	GO:0007126	4	0.013
positive regulation of rna biosynthetic process	GO:1902680	57	0.013
purine ribonucleoside catabolic process	GO:0046130	6	0.013
positive regulation of rna metabolic process	GO:0051254	59	0.013
meiotic chromosome segregation	GO:0045132	3	0.013
amine metabolic process	GO:0009308	2	0.013
adult behavior	GO:0030534	2	0.013
embryonic eye morphogenesis	GO:0048048	30	0.013
neuron development	GO:0048666	262	0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	20	0.013
regulation of cell shape	GO:0008360	1	0.012
regulation of growth	GO:0040008	42	0.012
dna metabolic process	GO:0006259	27	0.012
regulation of angiogenesis	GO:0045765	26	0.012
somitogenesis	GO:0001756	87	0.012
microtubule organizing center organization	GO:0031023	1	0.012
maternal determination of anterior posterior axis embryo	GO:0008358	4	0.012
regulation of vasculature development	GO:1901342	33	0.012
regulation of mrna processing	GO:0050684	3	0.012
immune system process	GO:0002376	241	0.012
cellular protein modification process	GO:0006464	100	0.012
cell morphogenesis involved in differentiation	GO:0000904	195	0.012
positive regulation of molecular function	GO:0044093	33	0.012
developmental programmed cell death	GO:0010623	4	0.012
positive regulation of apoptotic process	GO:0043065	29	0.012
vasculature development	GO:0001944	278	0.012
nucleoside triphosphate metabolic process	GO:0009141	9	0.011
segmentation	GO:0035282	97	0.011
muscle structure development	GO:0061061	196	0.011
establishment of localization in cell	GO:0051649	77	0.011
protein localization to membrane	GO:0072657	9	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	9	0.011
positive regulation of nucleoside metabolic process	GO:0045979	1	0.011
autophagy	GO:0006914	4	0.011
cell cell signaling	GO:0007267	52	0.011
kupffer s vesicle development	GO:0070121	50	0.011
protein processing	GO:0016485	12	0.011
cellular amine metabolic process	GO:0044106	2	0.011
regulation of inflammatory response	GO:0050727	2	0.011
regulation of cytoplasmic transport	GO:1903649	4	0.011
positive regulation of endopeptidase activity	GO:0010950	10	0.011
developmental growth	GO:0048589	166	0.011
regulation of mitotic cell cycle	GO:0007346	25	0.011
cytoplasm organization	GO:0007028	4	0.010
dna catabolic process	GO:0006308	1	0.010
positive regulation of gastrulation	GO:2000543	2	0.010
negative regulation of cell communication	GO:0010648	96	0.010
regulation of heart growth	GO:0060420	2	0.010
embryonic viscerocranium morphogenesis	GO:0048703	52	0.010
purine ribonucleotide catabolic process	GO:0009154	6	0.010
dicarboxylic acid transport	GO:0006835	1	0.010

cct5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.114
nervous system disease	DOID:863	0.114
charcot marie tooth disease	DOID:10595	0.059
neuropathy	DOID:870	0.059
charcot marie tooth disease type 2	DOID:0050539	0.059
neuromuscular disease	DOID:440	0.059
central nervous system disease	DOID:331	0.010
neurodegenerative disease	DOID:1289	0.010

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