Danio rerio

49 known processes

whsc1

Wolf-Hirschhorn syndrome candidate 1

(Aliases: wu:fi20c01,si:rp71-77d7.2,wu:fc12c04,fc12c04)

whsc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleobase containing compound biosynthetic processGO:00346542050.983
Mouse
negative regulation of biological processGO:00485193040.966
Mouse
heterocycle biosynthetic processGO:00181302150.960
Mouse
cellular macromolecule metabolic processGO:00442603910.948
cellular aromatic compound metabolic processGO:00067252950.936
Mouse
cellular nitrogen compound metabolic processGO:00346412900.934
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.929
Mouse
histone h3 k9 methylationGO:005156750.921
nitrogen compound metabolic processGO:00068073190.905
Mouse
regulation of nitrogen compound metabolic processGO:00511712510.901
Mouse
histone lysine methylationGO:0034968120.882
histone h3 k9 modificationGO:006164750.875
negative regulation of cellular processGO:00485232830.864
Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.848
Mouse
negative regulation of gene expressionGO:0010629650.845
Mouse
organic substance biosynthetic processGO:19015762890.843
Mouse
regulation of metabolic processGO:00192223590.842
Mouse
cellular macromolecule biosynthetic processGO:00346452240.831
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.830
Mouse
nucleic acid metabolic processGO:00903042440.829
Mouse
central nervous system developmentGO:00074173870.822
regulation of cellular metabolic processGO:00313233200.813
Mouse
rna biosynthetic processGO:00327741810.798
Mouse
regulation of macromolecule biosynthetic processGO:00105562250.769
Mouse
chromatin modificationGO:0016568210.749
regulation of gene expressionGO:00104682650.741
Mouse
regulation of rna biosynthetic processGO:20011412130.736
Mouse
macromolecule biosynthetic processGO:00090592270.734
Mouse
histone methylationGO:0016571130.725
heterocycle metabolic processGO:00464832900.724
Mouse
cellular biosynthetic processGO:00442492860.711
Mouse
methylationGO:0032259220.711
organic cyclic compound metabolic processGO:19013603010.693
Mouse
head developmentGO:00603223030.686
nucleobase containing compound metabolic processGO:00061392740.685
Mouse
protein alkylationGO:0008213130.679
biosynthetic processGO:00090582940.657
Mouse
negative regulation of cellular biosynthetic processGO:0031327550.633
Mouse
protein methylationGO:0006479130.615
transcription dna templatedGO:00063511810.603
Mouse
nucleic acid templated transcriptionGO:00976591810.571
Mouse
single organism organelle organizationGO:19025891990.564
cellular nitrogen compound biosynthetic processGO:00442712180.552
Mouse
gene expressionGO:00104672520.513
Mouse
sensory organ developmentGO:00074233930.511
digestive system developmentGO:00551232890.511
single organism metabolic processGO:00447102170.506
regulation of macromolecule metabolic processGO:00602553170.499
Mouse
embryo development ending in birth or egg hatchingGO:00097922710.486
regulation of biosynthetic processGO:00098892500.473
Mouse
generation of neuronsGO:00486993850.458
negative regulation of transcription dna templatedGO:0045892450.454
Mouse
aromatic compound biosynthetic processGO:00194382170.444
Mouse
sexual reproductionGO:0019953360.440
negative regulation of nucleic acid templated transcriptionGO:1903507450.431
Mouse
organelle organizationGO:00069962270.428
histone modificationGO:0016570200.424
histone h3 k4 methylationGO:005156820.424
negative regulation of macromolecule metabolic processGO:0010605760.416
Mouse
regulation of cellular biosynthetic processGO:00313262450.414
Mouse
regulation of transcription dna templatedGO:00063552130.403
Mouse
organic cyclic compound biosynthetic processGO:19013622230.398
Mouse
negative regulation of nucleobase containing compound metabolic processGO:0045934590.385
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063571140.384
Mouse
histone h4 k20 methylationGO:003477020.360
Mouse
regulation of rna metabolic processGO:00512522240.348
Mouse
rna metabolic processGO:00160702190.346
Mouse
negative regulation of biosynthetic processGO:0009890550.308
Mouse
neuron developmentGO:00486662620.307
transcription from rna polymerase ii promoterGO:0006366800.299
Mouse
skeletal system developmentGO:00015011810.290
eye developmentGO:00016542770.279
covalent chromatin modificationGO:0016569200.277
regulation of primary metabolic processGO:00800903110.274
Mouse
histone h3 k36 methylationGO:001045220.271
negative regulation of macromolecule biosynthetic processGO:0010558480.271
Mouse
response to stressGO:00069502630.267
Mouse
brain developmentGO:00074202930.267
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.262
Mouse
protein metabolic processGO:00195381830.256
negative regulation of cellular metabolic processGO:0031324770.251
Mouse
negative regulation of ras protein signal transductionGO:004658010.249
regulation of histone methylationGO:003106030.248
dna alkylationGO:000630580.235
cell morphogenesisGO:00009022890.234
regulation of gene expression epigeneticGO:0040029110.231
negative regulation of metabolic processGO:0009892860.221
Mouse
signal transductionGO:00071654550.219
tube morphogenesisGO:00352393490.213
macromolecule modificationGO:00434121110.207
negative regulation of cell differentiationGO:0045596460.201
digestive tract developmentGO:00485652650.200
negative regulation of nitrogen compound metabolic processGO:0051172590.200
Mouse
dna modificationGO:000630480.193
negative regulation of rna metabolic processGO:0051253480.189
Mouse
growthGO:00400071740.185
response to inorganic substanceGO:0010035380.182
peptidyl lysine trimethylationGO:001802310.180
spindle assemblyGO:005122520.176
cellular component biogenesisGO:00440851780.173
regulation of histone h3 k9 methylationGO:005157020.173
cellular component morphogenesisGO:00329893360.172
larval developmentGO:000216420.172
negative regulation of signalingGO:0023057960.164
negative regulation of small gtpase mediated signal transductionGO:005105810.152
cellular protein modification processGO:00064641000.146
nuclear migrationGO:000709730.145
gamete generationGO:0007276330.138
regulation of cell differentiationGO:00455951420.137
protein modification processGO:00362111000.135
mitotic cell cycle processGO:1903047480.135
dna metabolic processGO:0006259270.133
Mouse
cell projection morphogenesisGO:00488582440.133
dna methylation or demethylationGO:004472880.132
regulation of multicellular organism growthGO:004001440.129
response to chemicalGO:00422213200.127
stem cell maintenanceGO:001982740.125
multi organism processGO:00517041340.125
regulation of cell communicationGO:00106462320.123
centrosome organizationGO:005129710.121
macromolecular complex subunit organizationGO:0043933740.121
macromolecule methylationGO:0043414190.118
chromosome organizationGO:0051276310.117
peptidyl lysine dimethylationGO:001802710.117
neuron differentiationGO:00301823530.115
developmental growthGO:00485891660.113
dna methylationGO:000630680.109
regulation of developmental processGO:00507932470.107
Mouse
agingGO:000756820.107
positive regulation of gtpase activityGO:004354710.107
multicellular organism growthGO:003526440.107
multi organism reproductive processGO:0044703360.106
cell projection organizationGO:00300302840.106
positive regulation of gtp catabolic processGO:003312610.103
guanosine containing compound catabolic processGO:190106920.100
negative regulation of developmental processGO:0051093650.100
regulation of cellular amine metabolic processGO:003323800.099
exocrine pancreas developmentGO:0031017280.099
cellular component assemblyGO:00226071700.098
ras protein signal transductionGO:000726570.098
gtp catabolic processGO:000618420.096
regulation of chromosome segregationGO:005198310.095
protein acetylationGO:000647320.094
g2 m transition of mitotic cell cycleGO:000008640.093
response to external stimulusGO:00096052640.093
reproductionGO:0000003400.092
g1 s transition of mitotic cell cycleGO:000008210.092
cellular protein metabolic processGO:00442671290.091
protein acylationGO:004354330.090
positive regulation of purine nucleotide catabolic processGO:003312310.089
regenerationGO:0031099910.086
cell part morphogenesisGO:00329902460.086
cell fate commitmentGO:0045165990.086
negative regulation of histone methylationGO:003106110.083
regulation of stem cell differentiationGO:200073640.079
establishment of localizationGO:00512342440.079
Mouse
immune system developmentGO:00025201910.079
Mouse
negative regulation of rna biosynthetic processGO:1902679450.077
Mouse
response to radiationGO:0009314510.077
chromatin organizationGO:0006325220.075
response to drugGO:004249330.074
response to organic substanceGO:00100331530.074
positive regulation of cellular processGO:00485222010.071
Mouse
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.071
muscle structure developmentGO:00610611960.070
cellular component movementGO:00069283350.070
multicellular organism reproductionGO:0032504350.070
internal protein amino acid acetylationGO:000647520.070
negative regulation of histone modificationGO:003105710.069
eye morphogenesisGO:00485921440.069
negative regulation of signal transductionGO:0009968940.069
chordate embryonic developmentGO:00430092710.067
regulation of growthGO:0040008420.066
intracellular signal transductionGO:0035556850.065
locomotionGO:00400113130.064
regulation of catalytic activityGO:0050790550.064
mesenchymal cell differentiationGO:0048762870.064
regulation of response to stimulusGO:00485832690.063
Mouse
cellular component assembly involved in morphogenesisGO:00109271070.063
regulation of gene silencingGO:006096810.061
phosphorylationGO:0016310690.060
gtp metabolic processGO:004603940.060
single organism localizationGO:19025782250.059
cellular localizationGO:0051641970.058
dna biosynthetic processGO:007189730.058
retina development in camera type eyeGO:00600411460.058
response to endogenous stimulusGO:0009719830.056
digestive tract morphogenesisGO:00485462310.056
positive regulation of map kinase activityGO:004340630.056
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.056
Mouse
regulation of protein metabolic processGO:0051246560.056
camera type eye developmentGO:00430102220.055
embryonic skeletal system developmentGO:0048706970.055
regulation of gtp catabolic processGO:003312420.054
cell morphogenesis involved in neuron differentiationGO:00486671630.054
regulation of dna metabolic processGO:0051052110.054
Mouse
small gtpase mediated signal transductionGO:000726480.054
positive regulation of chromatin modificationGO:190331010.053
negative regulation of cell communicationGO:0010648960.052
response to cadmium ionGO:0046686140.052
internal peptidyl lysine acetylationGO:001839320.052
stem cell developmentGO:0048864820.051
response to metal ionGO:0010038340.051
axon developmentGO:00615641660.050
mitotic nuclear divisionGO:0007067180.050
positive regulation of cellular amino acid metabolic processGO:004576400.049
macromolecular complex assemblyGO:0065003350.049
regulation of chromatin organizationGO:190227550.048
dna methylation on cytosineGO:003277630.047
positive regulation of nucleotide catabolic processGO:003081310.047
regulation of multicellular organismal processGO:00512392770.047
Mouse
amine metabolic processGO:000930820.047
cell proliferationGO:0008283800.047
negative regulation of response to stimulusGO:00485851040.047
deathGO:00162651210.046
response to light stimulusGO:0009416460.046
small molecule metabolic processGO:0044281770.045
regulation of apoptotic processGO:0042981980.045
transportGO:00068102200.045
mitotic cell cycleGO:0000278640.044
gene silencingGO:001645840.044
sensory organ morphogenesisGO:00905962000.043
response to amino acidGO:004320020.043
cell cycle g1 s phase transitionGO:004484310.043
regulation of purine nucleotide catabolic processGO:003312120.042
regulation of nucleoside metabolic processGO:000911820.042
regulation of signalingGO:00230512350.041
positive regulation of gene expressionGO:0010628710.041
epithelial cell differentiationGO:00308551160.040
positive regulation of nucleic acid templated transcriptionGO:1903508570.040
mesenchyme developmentGO:00604851270.040
regionalizationGO:00030022740.039
oogenesisGO:0048477140.039
mitotic dna integrity checkpointGO:004477440.039
negative regulation of dna metabolic processGO:005105340.039
negative regulation of intracellular signal transductionGO:1902532220.039
stem cell proliferationGO:007208940.038
establishment of nucleus localizationGO:004002370.038
guanosine containing compound metabolic processGO:190106840.038
positive regulation of catalytic activityGO:0043085250.038
segmentationGO:0035282970.038
cellular response to external stimulusGO:007149620.037
regulation of protein transportGO:005122330.037
positive regulation of cell cycleGO:004578730.037
axonogenesisGO:00074091520.037
apoptotic processGO:00069151160.037
striated muscle cell differentiationGO:00511461290.037
cellular response to stressGO:0033554620.036
Mouse
connective tissue developmentGO:0061448990.036
organic acid metabolic processGO:0006082310.036
pancreas developmentGO:0031016840.035
cellular process involved in reproduction in multicellular organismGO:0022412280.035
cellular amine metabolic processGO:004410620.035
regulation of dna methylationGO:004403050.035
reciprocal dna recombinationGO:003582510.035
muscle organ developmentGO:00075171010.035
response to nutrientGO:000758430.035
heart developmentGO:00075073130.034
Mouse
single organism reproductive processGO:0044702400.034
retina morphogenesis in camera type eyeGO:0060042790.034
hemopoiesisGO:00300971830.034
protein complex assemblyGO:0006461300.034
embryonic heart tube developmentGO:00350501330.034
phosphorus metabolic processGO:00067931090.033
response to vitaminGO:003327330.033
camera type eye morphogenesisGO:00485931080.033
cell cycle processGO:0022402530.033
muscle cell differentiationGO:00426921390.033
positive regulation of nucleoside metabolic processGO:004597910.033
negative regulation of chromosome organizationGO:200125110.033
cytoskeleton organizationGO:0007010960.032
cell deathGO:00082191210.031
response to abiotic stimulusGO:00096281220.031
positive regulation of transportGO:005105020.031
macromolecule localizationGO:0033036540.031
Mouse
centrosome duplicationGO:005129810.031
response to uvGO:000941130.030
chromosome segregationGO:0007059120.030
regulation of cellular component organizationGO:0051128860.030
homeostatic processGO:00425921420.030
regulation of cell cycleGO:0051726520.030
cell cycle arrestGO:000705010.030
meiosis iGO:000712710.030
embryonic organ morphogenesisGO:00485622740.030
germ cell developmentGO:0007281220.030
regulation of dna replicationGO:000627530.029
regulation of cellular ketone metabolic processGO:001056570.029
oxoacid metabolic processGO:0043436310.029
programmed cell deathGO:00125011190.029
regulation of nucleotide catabolic processGO:003081120.029
reproductive processGO:0022414400.028
regulation of stem cell proliferationGO:007209120.028
localization of cellGO:00516742440.028
regulation of mitotic cell cycleGO:0007346250.028
regulation of signal transductionGO:00099662250.028
posttranscriptional gene silencing by rnaGO:003519430.028
muscle tissue developmentGO:00605371100.028
double strand break repair via nonhomologous end joiningGO:000630310.028
Mouse
negative regulation of protein phosphorylationGO:000193340.027
determination of left right symmetryGO:00073681790.027
regulation of gtpase activityGO:004308720.026
regulation of cell proliferationGO:0042127370.026
establishment of organelle localizationGO:0051656450.026
positive regulation of cellular catabolic processGO:003133130.026
positive regulation of developmental processGO:0051094500.026
Mouse
regulation of cellular amino acid metabolic processGO:000652100.026
cellular response to chemical stimulusGO:00708871570.025
carboxylic acid metabolic processGO:0019752220.025
meiotic cell cycle processGO:190304630.025
positive regulation of neural precursor cell proliferationGO:200017910.025
hematopoietic or lymphoid organ developmentGO:00485341910.025
cell morphogenesis involved in differentiationGO:00009041950.025
cell surface receptor signaling pathwayGO:00071663250.024
microtubule organizing center organizationGO:003102310.024
regulation of intracellular protein transportGO:003315730.024
maintenance of locationGO:005123540.023
cilium morphogenesisGO:0060271850.023
positive regulation of cellular amine metabolic processGO:003324000.023
regulation of dna recombinationGO:000001820.023
Mouse
positive regulation of cell developmentGO:0010720250.023
reciprocal meiotic recombinationGO:000713110.023
male meiosisGO:000714020.023
tissue regenerationGO:0042246740.022
epithelial cell morphogenesisGO:000338220.022
cell agingGO:000756920.022
system processGO:00030081850.022
positive regulation of cytosolic calcium ion concentrationGO:000720440.022
protein complex localizationGO:003150310.022
centrosome cycleGO:000709810.022
single organism transportGO:00447652060.022
fertilizationGO:000956630.022
meiotic spindle organizationGO:000021210.021
positive regulation of transcription dna templatedGO:0045893570.021
negative regulation of chromatin modificationGO:190330910.021
meiotic nuclear divisionGO:000712640.021
positive regulation of catabolic processGO:000989640.021
response to organic cyclic compoundGO:0014070510.021
embryonic heart tube morphogenesisGO:00031431080.021
response to steroid hormoneGO:0048545350.021
positive regulation of hydrolase activityGO:0051345130.021
multicellular organismal reproductive processGO:0048609350.021
regulation of programmed cell deathGO:00430671010.021
mitotic cell cycle embryonicGO:004544820.020
myofibril assemblyGO:0030239480.020
neuron projection morphogenesisGO:00488121610.020
immune system processGO:00023762410.020
Mouse
positive regulation of biological processGO:00485182530.020
Mouse
heterocycle catabolic processGO:0046700150.020
regulation of epidermis developmentGO:004568220.020
response to alcoholGO:0097305140.020
embryonic organ developmentGO:00485683810.019
fin regenerationGO:0031101510.019
positive regulation of dna metabolic processGO:005105410.019
Mouse
regulation of protein complex assemblyGO:004325430.019
developmental maturationGO:0021700340.019
regulation of cellular protein metabolic processGO:0032268520.019
regulation of ras gtpase activityGO:003231820.018
anterior posterior pattern specificationGO:00099521520.018
gastrulationGO:00073692080.018
cell migrationGO:00164772370.018
regulation of phosphorylationGO:0042325260.018
negative regulation of meiotic cell cycleGO:005144710.018
organonitrogen compound metabolic processGO:1901564740.018
neuron projection developmentGO:00311751800.018
cell cycle g2 m phase transitionGO:004483940.018
response to woundingGO:00096111160.018
cell cycleGO:0007049930.017
protein importGO:001703830.017
cell motilityGO:00488702440.017
pronuclear migrationGO:003504610.017
nuclear transportGO:005116940.017
developmental process involved in reproductionGO:0003006270.017
regulation of epithelial to mesenchymal transitionGO:001071730.016
regulation of bindingGO:005109830.016
phosphate containing compound metabolic processGO:00067961080.016
maintenance of dna repeat elementsGO:004357020.016
mitotic dna damage checkpointGO:004477340.016
cytokinesisGO:000091030.016
peptidyl lysine methylationGO:001802230.016
Mouse
protein complex subunit organizationGO:0071822460.016
determination of heart left right asymmetryGO:00613711170.016
somatic cell dna recombinationGO:001644410.016
Mouse
single fertilizationGO:000733830.016
regulation of intracellular signal transductionGO:1902531570.016
single organism biosynthetic processGO:0044711710.016
regulation of cell deathGO:00109411030.016
response to glucocorticoidGO:005138410.016
neurological system processGO:0050877620.015
mesenchymal cell developmentGO:0014031780.015
lateral inhibitionGO:004633110.015
positive regulation of cellular metabolic processGO:0031325940.015
Mouse
cellular response to organic substanceGO:00713101050.015
regulation of response to stressGO:0080134360.015
Mouse
regulation of mitotic cell cycle phase transitionGO:190199080.015
exocrine system developmentGO:0035272280.015
regulation of phosphorus metabolic processGO:0051174430.015
cellular response to endogenous stimulusGO:0071495680.015
cardiocyte differentiationGO:0035051440.015
striated muscle tissue developmentGO:00147061100.015
synaptic growth at neuromuscular junctionGO:005112420.015
posttranscriptional regulation of gene expressionGO:0010608140.015
cellular response to extracellular stimulusGO:003166820.015
regulation of transportGO:0051049450.015
regulation of establishment of protein localizationGO:007020140.015
Mouse
cellular amino acid metabolic processGO:000652070.014
eye photoreceptor cell developmentGO:0042462300.014
gliogenesisGO:0042063450.014
taxisGO:00423301090.014
positive regulation of histone modificationGO:003105810.014
cellular ketone metabolic processGO:0042180110.014
morphogenesis of an epitheliumGO:00020093330.014
stem cell differentiationGO:00488631170.014
transcription elongation from rna polymerase ii promoterGO:000636830.014
positive regulation of macromolecule biosynthetic processGO:0010557590.014
purine containing compound metabolic processGO:0072521290.014
negative regulation of multicellular organismal processGO:0051241690.014
regulation of cell developmentGO:00602841000.013
regulation of protein targetingGO:190353320.013
b cell differentiationGO:003018310.013
response to estrogenGO:0043627270.013
microtubule based processGO:0007017600.013
negative regulation of mitotic cell cycleGO:0045930110.013
compound eye developmentGO:004874920.013
positive regulation of ras gtpase activityGO:003232010.013
positive regulation of cellular component biogenesisGO:004408930.013
actin filament based processGO:0030029640.013
peptidyl lysine acetylationGO:001839420.013
response to corticosteroidGO:003196010.013
response to hormoneGO:0009725480.013
determination of bilateral symmetryGO:00098552040.013
regulation of neurogenesisGO:0050767870.013
negative regulation of protein kinase activityGO:000646940.012
dna templated transcription elongationGO:000635430.012
peptidyl amino acid modificationGO:0018193160.012
Mouse
positive regulation of nitrogen compound metabolic processGO:0051173690.012
Mouse
positive regulation of biosynthetic processGO:0009891680.012
regulation of dna templated transcription elongationGO:003278430.012
regulation of developmental growthGO:0048638380.012
positive regulation of chromosome organizationGO:200125210.012
wound healingGO:0042060900.012
rna localizationGO:000640340.012
female gamete generationGO:0007292140.012
negative regulation of apoptotic processGO:0043066550.011
inner ear developmentGO:00488391260.011
negative regulation of cellular component organizationGO:0051129160.011
positive regulation of nucleotide metabolic processGO:004598190.011
dicarboxylic acid metabolic processGO:004364810.011
regulation of chromosome organizationGO:003304450.011
response to nitrogen compoundGO:1901698190.011
extrinsic apoptotic signaling pathwayGO:009719130.011
hepaticobiliary system developmentGO:0061008980.011
multicellular organismal signalingGO:0035637220.011
response to oxygen containing compoundGO:1901700550.011
epidermal cell differentiationGO:0009913360.011
negative regulation of kinase activityGO:003367340.011
phagocytosisGO:000690930.011
microtubule based movementGO:0007018330.011
striated muscle cell developmentGO:00550021080.011
cranial nerve developmentGO:0021545420.011
positive regulation of signal transductionGO:0009967560.011
circulatory system processGO:0003013870.011
negative regulation of nuclear divisionGO:005178430.011
cilium organizationGO:0044782710.011
actomyosin structure organizationGO:0031032530.011
caudal fin developmentGO:003333690.010
regulation of histone modificationGO:003105650.010
neuron projection guidanceGO:0097485860.010
cartilage developmentGO:0051216960.010
mrna transportGO:005102820.010
positive regulation of stem cell proliferationGO:200064810.010
regulation of anatomical structure morphogenesisGO:00226031300.010
development of primary female sexual characteristicsGO:004654540.010
organophosphate metabolic processGO:0019637370.010
rna 3 end processingGO:003112320.010

whsc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
physical disorderDOID:008001500.028
disease of anatomical entityDOID:700.012
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.012
musculoskeletal system diseaseDOID:1700.012