Danio rerio

0 known processes

pif1

PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)

(Aliases: cb934,wu:fe11d03,zgc:56161,fe11d03)

pif1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spindle assemblyGO:005122520.407
centrosome duplicationGO:005129810.324
regulation of protein modification by small protein conjugation or removalGO:190332030.298
spindle assembly involved in mitosisGO:009030710.296
generation of neuronsGO:00486993850.273
regulation of protein ubiquitinationGO:003139630.229
modification dependent protein catabolic processGO:001994130.220
larval developmentGO:000216420.209
regulation of meiotic cell cycleGO:005144510.193
centrosome organizationGO:005129710.184
microtubule organizing center organizationGO:003102310.158
positive regulation of cell cycleGO:004578730.155
oocyte maturationGO:000155640.145
neuron differentiationGO:00301823530.143
cellular protein catabolic processGO:004425740.142
embryo development ending in birth or egg hatchingGO:00097922710.136
centrosome cycleGO:000709810.135
stem cell maintenanceGO:001982740.134
neuron developmentGO:00486662620.125
cytoskeleton dependent cytokinesisGO:006164030.112
signal transductionGO:00071654550.110
cell cycle g2 m phase transitionGO:004483940.108
maintenance of locationGO:005123540.106
mitotic dna integrity checkpointGO:004477440.104
cytokinesisGO:000091030.099
meiosis iGO:000712710.099
negative regulation of cellular processGO:00485232830.097
cell cycleGO:0007049930.096
g2 dna damage checkpointGO:003157230.095
proteolysis involved in cellular protein catabolic processGO:005160330.093
organelle organizationGO:00069962270.092
regulation of bindingGO:005109830.090
regulation of chromosome segregationGO:005198310.089
mitotic cytokinesisGO:000028130.085
cell cycle processGO:0022402530.084
gene expressionGO:00104672520.084
organelle fissionGO:0048285230.082
positive regulation of biological processGO:00485182530.082
meiotic cell cycle processGO:190304630.081
regulation of protein catabolic processGO:004217610.081
single organism organelle organizationGO:19025891990.079
sensory organ developmentGO:00074233930.078
heterocycle metabolic processGO:00464832900.078
cellular macromolecule metabolic processGO:00442603910.077
stem cell developmentGO:0048864820.077
regulation of biological qualityGO:00650082630.076
cytoskeleton organizationGO:0007010960.076
mitotic cell cycleGO:0000278640.075
eye developmentGO:00016542770.073
negative regulation of biological processGO:00485193040.072
regulation of organelle organizationGO:0033043290.071
regulation of gene expressionGO:00104682650.070
female meiotic divisionGO:000714320.070
ubiquitin dependent protein catabolic processGO:000651130.069
regulation of metabolic processGO:00192223590.068
regulation of protein transportGO:005122330.068
nucleic acid metabolic processGO:00903042440.067
negative regulation of mitosisGO:004583930.065
microtubule based processGO:0007017600.063
regulation of organelle assemblyGO:190211540.062
regulation of establishment of protein localizationGO:007020140.062
guanosine containing compound catabolic processGO:190106920.061
microtubule cytoskeleton organizationGO:0000226330.061
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.061
g2 m transition of mitotic cell cycleGO:000008640.061
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.060
establishment of localizationGO:00512342440.060
positive regulation of cellular processGO:00485222010.059
organelle assemblyGO:00709251100.058
apoptotic processGO:00069151160.058
mitotic cell cycle embryonicGO:004544820.058
compound eye developmentGO:004874920.057
positive regulation of cellular catabolic processGO:003133130.056
eye morphogenesisGO:00485921440.056
microtubule cytoskeleton organization involved in mitosisGO:190285010.056
agingGO:000756820.055
cellular protein metabolic processGO:00442671290.055
protein metabolic processGO:00195381830.054
positive regulation of nucleoside metabolic processGO:004597910.054
meiotic spindle organizationGO:000021210.053
single organism localizationGO:19025782250.052
sensory organ morphogenesisGO:00905962000.052
cellular component morphogenesisGO:00329893360.051
nucleobase containing compound metabolic processGO:00061392740.051
gtp catabolic processGO:000618420.051
regulation of nucleoside metabolic processGO:000911820.050
regulation of nitrogen compound metabolic processGO:00511712510.049
negative regulation of chromosome organizationGO:200125110.049
protein polyubiquitinationGO:000020940.048
positive regulation of nucleotide catabolic processGO:003081310.048
positive regulation of cell divisionGO:005178120.048
stem cell differentiationGO:00488631170.048
peptidyl serine modificationGO:001820920.048
meiotic nuclear divisionGO:000712640.047
regulation of cell deathGO:00109411030.047
gland developmentGO:00487321430.046
spindle assembly involved in meiosisGO:009030610.046
macromolecule biosynthetic processGO:00090592270.046
stem cell proliferationGO:007208940.046
single organism metabolic processGO:00447102170.045
cellular nitrogen compound metabolic processGO:00346412900.044
establishment of protein localization to organelleGO:007259440.044
regulation of macromolecule metabolic processGO:00602553170.043
biosynthetic processGO:00090582940.043
protein complex subunit organizationGO:0071822460.043
cell surface receptor signaling pathwayGO:00071663250.042
guanosine containing compound metabolic processGO:190106840.042
gtp metabolic processGO:004603940.042
regulation of cellular protein catabolic processGO:190336210.042
cellular response to chemical stimulusGO:00708871570.042
negative regulation of cellular catabolic processGO:003133030.042
regulation of cell differentiationGO:00455951420.041
regulation of cell cycleGO:0051726520.041
regulation of purine nucleotide catabolic processGO:003312120.040
negative regulation of nuclear divisionGO:005178430.040
mitotic g2 m transition checkpointGO:004481830.040
male meiosisGO:000714020.040
protein complex assemblyGO:0006461300.039
organic cyclic compound metabolic processGO:19013603010.039
regulation of catalytic activityGO:0050790550.038
regulation of dendrite developmentGO:005077330.038
regulation of gtp catabolic processGO:003312420.038
mitotic nuclear divisionGO:0007067180.038
chordate embryonic developmentGO:00430092710.038
regulation of cell communicationGO:00106462320.038
regulation of protein import into nucleusGO:004230620.037
macromolecule modificationGO:00434121110.036
negative regulation of protein localization to nucleusGO:190018120.036
positive regulation of catabolic processGO:000989640.036
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.036
rna metabolic processGO:00160702190.036
negative regulation of protein transportGO:005122430.035
regulation of cellular metabolic processGO:00313233200.035
nuclear divisionGO:0000280230.035
positive regulation of purine nucleotide catabolic processGO:003312310.035
protein complex disassemblyGO:004324110.035
regulation of cellular component organizationGO:0051128860.034
positive regulation of nitrogen compound metabolic processGO:0051173690.034
meiosis iiGO:000713510.034
somatic muscle developmentGO:000752540.034
multicellular organism growthGO:003526440.034
regulation of gtpase activityGO:004308720.033
cell projection organizationGO:00300302840.033
cellular aromatic compound metabolic processGO:00067252950.033
regulation of nucleobase containing compound metabolic processGO:00192192500.032
positive regulation of metabolic processGO:00098931080.032
regulation of molecular functionGO:0065009700.032
regulation of response to stimulusGO:00485832690.031
regulation of synapse organizationGO:005080730.031
protein complex biogenesisGO:0070271300.031
regulation of intracellular protein transportGO:003315730.031
phagocytosisGO:000690930.031
protein targeting to nucleusGO:004474430.031
transportGO:00068102200.031
cytokinetic processGO:003250620.031
nitrogen compound metabolic processGO:00068073190.030
protein localization to microtubule cytoskeletonGO:007269810.030
digestive system developmentGO:00551232890.030
cell deathGO:00082191210.030
regulation of neurogenesisGO:0050767870.030
mesenchyme developmentGO:00604851270.029
stem cell fate commitmentGO:004886510.029
locomotionGO:00400113130.029
regulation of protein localization to nucleusGO:190018020.029
regulation of microtubule cytoskeleton organizationGO:007050730.029
single organism transportGO:00447652060.029
deathGO:00162651210.028
regulation of nucleocytoplasmic transportGO:004682220.028
macromolecule localizationGO:0033036540.028
regulation of cell cycle processGO:0010564200.028
single organism nuclear importGO:190259330.028
regulation of protein targetingGO:190353320.028
sex determinationGO:000753010.028
macromolecular complex disassemblyGO:003298410.028
response to stressGO:00069502630.028
negative regulation of cell cycle processGO:001094890.027
modification dependent macromolecule catabolic processGO:004363230.027
immune system processGO:00023762410.027
chromosome segregationGO:0007059120.027
positive regulation of gtp catabolic processGO:003312610.027
positive regulation of cellular metabolic processGO:0031325940.027
peripheral nervous system developmentGO:0007422550.027
hematopoietic or lymphoid organ developmentGO:00485341910.027
cellular protein modification processGO:00064641000.026
neuroblast proliferationGO:000740520.026
proteasomal protein catabolic processGO:001049820.026
regulation of nucleotide catabolic processGO:003081120.026
cell fate commitmentGO:0045165990.026
regulation of signal transductionGO:00099662250.026
cellular component disassemblyGO:002241110.026
aromatic compound biosynthetic processGO:00194382170.026
proteolysisGO:0006508380.026
regulation of primary metabolic processGO:00800903110.026
meiotic chromosome segregationGO:004513230.026
cellular macromolecule biosynthetic processGO:00346452240.025
regulation of cytoplasmic transportGO:190364940.025
organic substance biosynthetic processGO:19015762890.025
nucleobase containing compound biosynthetic processGO:00346542050.025
multi organism processGO:00517041340.025
mitotic cell cycle processGO:1903047480.024
protein importGO:001703830.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
neuron projection developmentGO:00311751800.024
positive regulation of gtpase activityGO:004354710.024
nuclear importGO:005117030.024
response to lipidGO:0033993600.024
cell cycle g1 s phase transitionGO:004484310.023
programmed cell deathGO:00125011190.023
microtubule based movementGO:0007018330.023
regulation of cell shapeGO:000836010.023
regulation of signalingGO:00230512350.022
peptidyl serine phosphorylationGO:001810510.022
cell projection morphogenesisGO:00488582440.022
negative regulation of cell communicationGO:0010648960.022
protein localizationGO:0008104400.022
neuroblast fate commitmentGO:001401710.022
regulation of dna replicationGO:000627530.022
rna biosynthetic processGO:00327741810.021
positive regulation of chromosome segregationGO:005198410.021
regulation of stem cell proliferationGO:007209120.021
thymus developmentGO:0048538100.021
negative regulation of cell deathGO:0060548600.021
regulation of rna metabolic processGO:00512522240.021
regulation of mitotic cell cycleGO:0007346250.020
regulation of synaptic plasticityGO:004816710.020
heterocycle biosynthetic processGO:00181302150.020
regulation of neuron differentiationGO:0045664560.020
protein localization to nucleusGO:003450430.020
retina development in camera type eyeGO:00600411460.020
protein depolymerizationGO:005126110.020
negative regulation of catabolic processGO:000989530.020
protein modification processGO:00362111000.020
regulation of protein bindingGO:004339330.020
mitotic dna damage checkpointGO:004477340.020
enzyme linked receptor protein signaling pathwayGO:00071671060.020
regulation of wnt signaling pathwayGO:0030111530.019
negative regulation of protein import into nucleusGO:004230820.019
response to organic substanceGO:00100331530.019
camera type eye morphogenesisGO:00485931080.019
organelle fusionGO:004828430.019
mitotic spindle organizationGO:000705250.019
cell proliferationGO:0008283800.019
brain developmentGO:00074202930.019
macromolecular complex subunit organizationGO:0043933740.019
sister chromatid segregationGO:000081960.019
regulation of mitosisGO:000708890.019
regulation of cell cycle phase transitionGO:190198780.019
cell cycle arrestGO:000705010.019
regulation of apoptotic processGO:0042981980.019
heart developmentGO:00075073130.019
oxoacid metabolic processGO:0043436310.018
homeostatic processGO:00425921420.018
regulation of nucleic acid templated transcriptionGO:19035062130.018
small gtpase mediated signal transductionGO:000726480.018
cleavage furrow formationGO:003608920.018
nucleic acid templated transcriptionGO:00976591810.018
regulation of cell developmentGO:00602841000.018
cellular response to biotic stimulusGO:007121630.018
catabolic processGO:0009056320.018
epithelial cell differentiationGO:00308551160.018
mesenchymal cell developmentGO:0014031780.018
chromosome organization involved in meiosisGO:007019210.017
anterior posterior pattern specificationGO:00099521520.017
negative regulation of protein phosphorylationGO:000193340.017
amine metabolic processGO:000930820.017
regulation of nuclear divisionGO:005178390.017
negative regulation of developmental processGO:0051093650.017
cellular component assemblyGO:00226071700.017
negative regulation of intracellular protein transportGO:009031730.017
single organism biosynthetic processGO:0044711710.017
developmental programmed cell deathGO:001062340.017
protein polymerizationGO:005125840.017
digestive tract developmentGO:00485652650.016
photoreceptor cell differentiationGO:0046530550.016
positive regulation of transportGO:005105020.016
small molecule metabolic processGO:0044281770.016
protein dephosphorylationGO:000647030.016
vasculature developmentGO:00019442780.016
negative regulation of macromolecule metabolic processGO:0010605760.016
g1 s transition of mitotic cell cycleGO:000008210.016
regulation of protein metabolic processGO:0051246560.016
microtubule polymerization or depolymerizationGO:003110930.016
intracellular signal transductionGO:0035556850.016
regulation of programmed cell deathGO:00430671010.016
cellular ketone metabolic processGO:0042180110.016
organic acid metabolic processGO:0006082310.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
mitotic metaphase plate congressionGO:000708010.016
positive regulation of chromosome organizationGO:200125210.015
developmental cell growthGO:0048588520.015
cellular amino acid metabolic processGO:000652070.015
positive regulation of chromatin modificationGO:190331010.015
regulation of localizationGO:00328791040.015
embryonic organ developmentGO:00485683810.015
regulation of transcription dna templatedGO:00063552130.015
response to biotic stimulusGO:0009607970.015
regulation of multicellular organism growthGO:004001440.015
response to drugGO:004249330.015
maternal determination of anterior posterior axis embryoGO:000835840.015
spindle organizationGO:000705150.015
cellular component movementGO:00069283350.015
peptidyl threonine phosphorylationGO:001810710.015
regulation of rna biosynthetic processGO:20011412130.015
central nervous system developmentGO:00074173870.015
response to oxygen containing compoundGO:1901700550.015
negative regulation of gene expressionGO:0010629650.015
cellular amine metabolic processGO:004410620.014
protein modification by small protein conjugation or removalGO:0070647140.014
posttranscriptional regulation of gene expressionGO:0010608140.014
negative regulation of cell cycle phase transitionGO:190198850.014
pronuclear migrationGO:003504610.014
regulation of cellular protein metabolic processGO:0032268520.014
histone modificationGO:0016570200.014
negative regulation of rna metabolic processGO:0051253480.014
negative regulation of cytoplasmic transportGO:190365020.014
cellular localizationGO:0051641970.014
carboxylic acid metabolic processGO:0019752220.014
protein import into nucleusGO:000660630.014
stem cell divisionGO:001714510.014
organic cyclic compound biosynthetic processGO:19013622230.014
lateral inhibitionGO:004633110.014
transcription dna templatedGO:00063511810.014
dna integrity checkpointGO:003157060.014
cellular response to oxygen levelsGO:007145310.014
cellular process involved in reproduction in multicellular organismGO:0022412280.014
gamete generationGO:0007276330.014
rna 3 end processingGO:003112320.014
lipid storageGO:001991510.013
cell morphogenesisGO:00009022890.013
growthGO:00400071740.013
regulation of mitotic cell cycle phase transitionGO:190199080.013
microtubule depolymerizationGO:000701910.013
cell maturationGO:0048469230.013
nuclear migrationGO:000709730.013
neural crest cell differentiationGO:0014033720.013
spindle assembly involved in female meiosisGO:000705610.013
negative regulation of apoptotic processGO:0043066550.013
positive regulation of muscle tissue developmentGO:190186310.013
cellular response to decreased oxygen levelsGO:003629410.013
pancreas developmentGO:0031016840.013
regulation of protein complex assemblyGO:004325430.013
negative regulation of mitotic cell cycleGO:0045930110.013
histone phosphorylationGO:001657220.012
cell divisionGO:0051301200.012
nuclear transportGO:005116940.012
neural crest cell developmentGO:0014032620.012
production of molecular mediator of immune responseGO:000244020.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
cellular response to organic substanceGO:00713101050.012
regulation of neural precursor cell proliferationGO:200017730.012
b cell activationGO:004211320.012
negative regulation of protein kinase activityGO:000646940.012
morphogenesis of an epitheliumGO:00020093330.012
negative regulation of cell differentiationGO:0045596460.012
positive regulation of cellular amine metabolic processGO:003324000.012
neuroblast fate determinationGO:000740010.012
positive regulation of ras gtpase activityGO:003232010.012
reproductive processGO:0022414400.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
cell migration involved in gastrulationGO:0042074790.012
hatching gland developmentGO:004878530.012
regulation of ras gtpase activityGO:003231820.012
regulation of cytoskeleton organizationGO:0051493110.012
female meiosis iiGO:000714710.012
peptidyl threonine modificationGO:001821010.012
negative regulation of signal transductionGO:0009968940.012
leukocyte homeostasisGO:000177620.012
otic vesicle developmentGO:0071599420.012
negative regulation of signalingGO:0023057960.011
appendage developmentGO:0048736800.011
homologous chromosome segregationGO:004514310.011
regulation of organ growthGO:004662030.011
regulation of proteolysisGO:0030162240.011
regulation of exit from mitosisGO:000709630.011
cellular protein complex disassemblyGO:004362410.011
ectodermal placode developmentGO:0071696370.011
regulation of developmental processGO:00507932470.011
response to endogenous stimulusGO:0009719830.011
microtubule polymerizationGO:004678520.011
determination of left right symmetryGO:00073681790.011
response to external biotic stimulusGO:0043207970.011
ras protein signal transductionGO:000726570.011
muscle structure developmentGO:00610611960.011
gastrulationGO:00073692080.011
protein modification by small protein conjugationGO:0032446130.011
protein phosphorylationGO:0006468470.011
regulation of intracellular signal transductionGO:1902531570.011
negative regulation of molecular functionGO:0044092230.011
cellular component biogenesisGO:00440851780.011
photoreceptor cell developmentGO:0042461400.011
positive regulation of cytoskeleton organizationGO:005149530.011
response to chemicalGO:00422213200.011
oocyte developmentGO:0048599140.011
transcription from rna polymerase ii promoterGO:0006366800.011
immune system developmentGO:00025201910.011
cell migrationGO:00164772370.011
developmental maturationGO:0021700340.011
blood vessel developmentGO:00015682460.011
negative regulation of response to stimulusGO:00485851040.011
wnt signaling pathwayGO:0016055800.011
response to hormoneGO:0009725480.011
positive regulation of muscle organ developmentGO:004863610.010
negative regulation of proteolysisGO:0045861100.010
autophagyGO:000691440.010
regulation of cellular component movementGO:0051270550.010
cellular response to hypoxiaGO:007145610.010
cellular response to endogenous stimulusGO:0071495680.010
rna localizationGO:000640340.010
mesenchymal cell differentiationGO:0048762870.010
developmental growth involved in morphogenesisGO:0060560860.010
negative regulation of rna biosynthetic processGO:1902679450.010
phosphorylationGO:0016310690.010
positive regulation of histone modificationGO:003105810.010
nuclear envelope organizationGO:000699820.010
embryonic cranial skeleton morphogenesisGO:0048701900.010
cellular response to molecule of bacterial originGO:007121930.010
negative regulation of mitotic cell cycle phase transitionGO:190199150.010
negative regulation of intracellular transportGO:003238730.010
regulation of rho protein signal transductionGO:003502320.010
mitotic sister chromatid segregationGO:000007060.010

pif1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.016
disease of anatomical entityDOID:700.012
organ system cancerDOID:005068600.012