Danio rerio

40 known processes

tnika

TRAF2 and NCK interacting kinase a

(Aliases: zgc:63535,fc52d11,wu:fc52d11,tnikl,msn)

tnika biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.138
Worm
sequestering of calcium ionGO:005120830.105
sequestering of metal ionGO:005123830.099
negative regulation of sequestering of calcium ionGO:005128340.086
regulation of sequestering of calcium ionGO:005128240.063
cellular macromolecule metabolic processGO:00442603910.062
Human
response to stressGO:00069502630.055
Human Fly
maintenance of locationGO:005123540.053
Worm
central nervous system developmentGO:00074173870.051
agingGO:000756820.050
cellular component morphogenesisGO:00329893360.049
adult behaviorGO:003053420.048
organelle organizationGO:00069962270.048
Human
protein metabolic processGO:00195381830.047
Human
negative regulation of biological processGO:00485193040.045
Fly
single organism membrane fusionGO:004480120.044
release of sequestered calcium ion into cytosolGO:005120930.042
gtp metabolic processGO:004603940.041
calcium ion transport into cytosolGO:006040230.041
signal transductionGO:00071654550.041
Human Fly
cellular component movementGO:00069283350.041
Worm Fly
regulation of metabolic processGO:00192223590.040
Human
organelle fusionGO:004828430.039
regulation of multicellular organism growthGO:004001440.036
regulation of biological qualityGO:00650082630.035
sensory organ developmentGO:00074233930.035
response to external stimulusGO:00096052640.034
Worm Fly
establishment of localizationGO:00512342440.033
Worm Fly
lipid storageGO:001991510.032
Worm
synaptic transmission cholinergicGO:000727140.032
neuron differentiationGO:00301823530.030
Human Worm Fly
membrane repolarizationGO:008600920.030
cellular protein catabolic processGO:004425740.029
cytosolic calcium ion transportGO:006040130.029
regulation of reproductive processGO:200024140.029
hormone biosynthetic processGO:004244630.029
modification dependent macromolecule catabolic processGO:004363230.028
membrane fusionGO:006102520.028
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.028
inorganic cation transmembrane transportGO:0098662500.027
regulation of nucleoside metabolic processGO:000911820.027
regulation of rna biosynthetic processGO:20011412130.027
positive regulation of cytosolic calcium ion concentrationGO:000720440.027
cell morphogenesisGO:00009022890.026
cellular response to external stimulusGO:007149620.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
proteasomal protein catabolic processGO:001049820.026
lateral inhibitionGO:004633110.025
single organism metabolic processGO:00447102170.025
Human Fly
regulation of cellular metabolic processGO:00313233200.025
Human
heterocycle metabolic processGO:00464832900.025
gtp catabolic processGO:000618420.025
cation transportGO:0006812810.025
i kappab kinase nf kappab signalingGO:000724940.025
regulation of signal transductionGO:00099662250.024
Human Fly
positive regulation of cell cycleGO:004578730.024
cell part morphogenesisGO:00329902460.024
Human Worm Fly
regulation of cell shapeGO:000836010.024
regulation of response to stimulusGO:00485832690.024
Human Fly
single organism organelle organizationGO:19025891990.024
Human
behaviorGO:0007610740.024
cell surface receptor signaling pathwayGO:00071663250.024
transportGO:00068102200.023
Worm
embryonic organ developmentGO:00485683810.023
purine nucleoside monophosphate catabolic processGO:000912840.023
multi organism processGO:00517041340.023
amine metabolic processGO:000930820.022
cell cycle g1 s phase transitionGO:004484310.022
chordate embryonic developmentGO:00430092710.022
deathGO:00162651210.022
cognitionGO:005089010.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
regulation of metal ion transportGO:001095940.022
establishment of protein localization to organelleGO:007259440.022
regulation of membrane potentialGO:0042391230.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
rna metabolic processGO:00160702190.021
determination of bilateral symmetryGO:00098552040.021
tube morphogenesisGO:00352393490.021
regulation of purine nucleotide catabolic processGO:003312120.021
specification of symmetryGO:00097992040.020
embryonic organ morphogenesisGO:00485622740.020
regulation of cell communicationGO:00106462320.020
Human Fly
locomotionGO:00400113130.020
Worm Fly
rna biosynthetic processGO:00327741810.020
purine ribonucleoside monophosphate catabolic processGO:000916940.020
regulation of nucleotide catabolic processGO:003081120.019
generation of neuronsGO:00486993850.019
Human Worm Fly
inorganic ion transmembrane transportGO:0098660570.019
transcription dna templatedGO:00063511810.019
nucleic acid metabolic processGO:00903042440.019
lipid homeostasisGO:005508830.019
guanosine containing compound metabolic processGO:190106840.019
cellular biosynthetic processGO:00442492860.019
heart developmentGO:00075073130.019
immune system developmentGO:00025201910.019
morphogenesis of an epitheliumGO:00020093330.019
autophagyGO:000691440.018
intracellular signal transductionGO:0035556850.018
Human Fly
protein acetylationGO:000647320.018
cellular nitrogen compound metabolic processGO:00346412900.018
regulation of synaptic plasticityGO:004816710.018
organic cyclic compound metabolic processGO:19013603010.018
head developmentGO:00603223030.018
macromolecule modificationGO:00434121110.018
Human
organic substance biosynthetic processGO:19015762890.018
endosomal transportGO:001619720.017
tissue remodelingGO:004877140.017
heterocycle biosynthetic processGO:00181302150.017
regulation of cytoplasmic transportGO:190364940.017
protein dephosphorylationGO:000647030.017
cell deathGO:00082191210.017
cation transmembrane transportGO:0098655650.017
negative regulation of cellular processGO:00485232830.017
Fly
digestive system developmentGO:00551232890.017
positive regulation of transportGO:005105020.017
multicellular organism growthGO:003526440.016
cellular protein metabolic processGO:00442671290.016
Human
protein modification processGO:00362111000.016
Human
brain developmentGO:00074202930.016
organonitrogen compound metabolic processGO:1901564740.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
anterior posterior pattern specificationGO:00099521520.016
ear developmentGO:00435831270.016
determination of left right symmetryGO:00073681790.016
aromatic compound biosynthetic processGO:00194382170.016
stem cell maintenanceGO:001982740.016
action potentialGO:0001508190.016
regulation of nitrogen compound metabolic processGO:00511712510.016
b cell activationGO:004211320.016
muscle structure developmentGO:00610611960.015
regulation of synapse organizationGO:005080730.015
nucleoside monophosphate catabolic processGO:000912540.015
gene expressionGO:00104672520.015
system processGO:00030081850.015
regulation of macromolecule metabolic processGO:00602553170.015
Human
cellular amine metabolic processGO:004410620.015
positive regulation of biological processGO:00485182530.015
Human
positive regulation of cellular processGO:00485222010.015
Human
regulation of signalingGO:00230512350.015
Human Fly
nitrogen compound metabolic processGO:00068073190.015
negative regulation of protein phosphorylationGO:000193340.015
regulation of primary metabolic processGO:00800903110.015
Human
response to chemicalGO:00422213200.015
Worm Fly
regulation of gtp catabolic processGO:003312420.015
protein polymerizationGO:005125840.015
cell projection morphogenesisGO:00488582440.015
Human Worm Fly
peptide metabolic processGO:000651810.015
female gonad developmentGO:000858540.015
modification dependent protein catabolic processGO:001994130.015
regulation of establishment of protein localizationGO:007020140.015
nuclear importGO:005117030.015
cellular aromatic compound metabolic processGO:00067252950.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
organic cyclic compound biosynthetic processGO:19013622230.015
sensory perception of chemical stimulusGO:000760630.015
positive regulation of catabolic processGO:000989640.014
embryo development ending in birth or egg hatchingGO:00097922710.014
Fly
regulation of cellular component organizationGO:0051128860.014
cellular response to radiationGO:007147840.014
rna localizationGO:000640340.014
regulation of cell differentiationGO:00455951420.014
Human
cellular protein modification processGO:00064641000.014
Human
guanosine containing compound catabolic processGO:190106920.014
regulation of macromolecule biosynthetic processGO:00105562250.014
cellular respirationGO:004533330.014
establishment of rna localizationGO:005123630.014
positive regulation of protein complex assemblyGO:003133420.014
protein localization to plasma membraneGO:007265910.014
cellular response to extracellular stimulusGO:003166820.014
meiotic nuclear divisionGO:000712640.014
nucleobase containing compound metabolic processGO:00061392740.014
cell motilityGO:00488702440.014
Worm
cell projection organizationGO:00300302840.013
Human Worm Fly
small molecule metabolic processGO:0044281770.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
g protein coupled receptor signaling pathwayGO:0007186740.013
nucleic acid transportGO:005065720.013
positive regulation of cellular catabolic processGO:003133130.013
protein homooligomerizationGO:005126030.013
apoptotic processGO:00069151160.013
macromolecule biosynthetic processGO:00090592270.013
cellular macromolecule biosynthetic processGO:00346452240.013
regulation of tube sizeGO:003515020.013
small molecule catabolic processGO:004428230.013
exocytosisGO:000688710.013
regulation of filopodium assemblyGO:005148920.013
inner ear developmentGO:00488391260.013
regulation of organ growthGO:004662030.013
apical junction assemblyGO:004329710.013
cellular localizationGO:0051641970.013
Fly
regionalizationGO:00030022740.013
regulation of developmental processGO:00507932470.013
regulation of biosynthetic processGO:00098892500.013
long chain fatty acid metabolic processGO:000167610.013
neurotransmitter transportGO:000683620.013
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
Human
g1 s transition of mitotic cell cycleGO:000008210.012
negative regulation of kinase activityGO:003367340.012
organic acid metabolic processGO:0006082310.012
regulation of gtpase activityGO:004308720.012
hepaticobiliary system developmentGO:0061008980.012
oxoacid metabolic processGO:0043436310.012
startle responseGO:000196440.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
ventricular cardiac muscle tissue developmentGO:000322930.012
muscle cell differentiationGO:00426921390.012
phosphorus metabolic processGO:00067931090.012
Human Fly
carboxylic acid metabolic processGO:0019752220.012
nucleobase containing compound biosynthetic processGO:00346542050.012
cellular response to nutrient levelsGO:003166920.012
central nervous system neuron differentiationGO:0021953740.012
cellular component disassemblyGO:002241110.012
regulation of nucleocytoplasmic transportGO:004682220.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
liver developmentGO:0001889960.012
nuclear transportGO:005116940.012
protein targeting to nucleusGO:004474430.012
establishment of synaptic vesicle localizationGO:009748010.011
regulation of cell activationGO:005086510.011
atp catabolic processGO:000620040.011
negative regulation of protein kinase activityGO:000646940.011
cell morphogenesis involved in differentiationGO:00009041950.011
Human Worm Fly
post golgi vesicle mediated transportGO:000689210.011
regulation of rna metabolic processGO:00512522240.011
regulation of muscle contractionGO:000693730.011
cell projection assemblyGO:0030031640.011
nucleic acid templated transcriptionGO:00976591810.011
divalent inorganic cation homeostasisGO:0072507220.011
gastrulationGO:00073692080.011
activation of mapk activityGO:000018730.011
Human
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
ubiquitin dependent protein catabolic processGO:000651130.011
regulation of bindingGO:005109830.011
regulation of multicellular organismal processGO:00512392770.011
Human Fly
phagocytosisGO:000690930.011
regulation of protein transportGO:005122330.011
wnt signaling pathwayGO:0016055800.011
neuromast developmentGO:0048884460.011
cortical cytoskeleton organizationGO:003086510.011
establishment of localization in cellGO:0051649770.011
Fly
sensory organ morphogenesisGO:00905962000.011
actin mediated cell contractionGO:007025210.011
protein importGO:001703830.011
biosynthetic processGO:00090582940.011
axon ensheathment in central nervous systemGO:003229120.011
cellular component assembly involved in morphogenesisGO:00109271070.011
regulation of protein import into nucleusGO:004230620.011
stem cell proliferationGO:007208940.011
neuron projection morphogenesisGO:00488121610.011
Human Worm Fly
cellular response to light stimulusGO:007148240.011
response to uvGO:000941130.010
single organism localizationGO:19025782250.010
neuroblast proliferationGO:000740520.010
hatchingGO:003518840.010
chemosensory behaviorGO:000763510.010
homeostatic processGO:00425921420.010
compound eye developmentGO:004874920.010
cellular amide metabolic processGO:004360340.010
negative regulation of multi organism processGO:004390130.010
regulation of blood vessel sizeGO:005088020.010
actin filament based movementGO:003004810.010
peptidyl lysine acetylationGO:001839420.010
regulation of protein complex assemblyGO:004325430.010
regulation of cell developmentGO:00602841000.010
Human

tnika disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
disease of metabolismDOID:001466700.021
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.016
organ system cancerDOID:005068600.016
nervous system diseaseDOID:86300.014
musculoskeletal system diseaseDOID:1700.012
inherited metabolic disorderDOID:65500.011
immune system diseaseDOID:291400.010
myopathyDOID:42300.010
intrinsic cardiomyopathyDOID:006003600.010
muscular diseaseDOID:008000000.010
heart diseaseDOID:11400.010
cardiomyopathyDOID:005070000.010
cardiovascular system diseaseDOID:128700.010
muscle tissue diseaseDOID:6600.010