Danio rerio

9 known processes

nsdhl

NAD(P) dependent steroid dehydrogenase-like

(Aliases: zgc:112474)

nsdhl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of transportGO:005105020.056
regulation of establishment of protein localizationGO:007020140.052
nucleocytoplasmic transportGO:000691340.049
multicellular organism growthGO:003526440.045
response to stressGO:00069502630.044
nitrogen compound metabolic processGO:00068073190.042
larval developmentGO:000216420.039
agingGO:000756820.039
nuclear transportGO:005116940.037
single organism organelle organizationGO:19025891990.037
cellular amino acid metabolic processGO:000652070.037
protein localization to nucleusGO:003450430.036
cellular protein catabolic processGO:004425740.035
regulation of protein transportGO:005122330.034
regulation of protein localization to nucleusGO:190018020.034
mitochondrion organizationGO:000700540.034
regulation of bindingGO:005109830.034
regulation of cytokine productionGO:000181730.033
amine metabolic processGO:000930820.033
cellular amine metabolic processGO:004410620.033
regulation of multicellular organism growthGO:004001440.033
signal transductionGO:00071654550.033
oxoacid metabolic processGO:0043436310.033
organelle fusionGO:004828430.032
organic acid metabolic processGO:0006082310.032
meiotic nuclear divisionGO:000712640.032
carboxylic acid metabolic processGO:0019752220.031
heterocycle metabolic processGO:00464832900.031
positive regulation of cellular catabolic processGO:003133130.031
organonitrogen compound metabolic processGO:1901564740.030
cellular response to external stimulusGO:007149620.030
cellular component assemblyGO:00226071700.030
positive regulation of small gtpase mediated signal transductionGO:005105710.030
phagocytosisGO:000690930.029
organelle organizationGO:00069962270.029
regulation of cellular ketone metabolic processGO:001056570.029
cytokinesisGO:000091030.029
organic substance biosynthetic processGO:19015762890.028
small molecule metabolic processGO:0044281770.028
regulation of intracellular protein transportGO:003315730.028
response to nutrientGO:000758430.028
cellular macromolecule metabolic processGO:00442603910.028
protein targeting to nucleusGO:004474430.027
ubiquitin dependent protein catabolic processGO:000651130.027
regulation of nucleoside metabolic processGO:000911820.027
immune system processGO:00023762410.027
negative regulation of biological processGO:00485193040.027
adult behaviorGO:003053420.027
biosynthetic processGO:00090582940.026
regulation of cytoplasmic transportGO:190364940.026
morphogenesis of an epitheliumGO:00020093330.025
nucleobase containing compound biosynthetic processGO:00346542050.025
carboxylic acid catabolic processGO:004639530.025
sensory organ developmentGO:00074233930.025
regulation of extrinsic apoptotic signaling pathwayGO:200123630.025
gland developmentGO:00487321430.025
cellular aromatic compound metabolic processGO:00067252950.025
positive regulation of nucleoside metabolic processGO:004597910.024
proteolysis involved in cellular protein catabolic processGO:005160330.024
response to drugGO:004249330.024
response to corticosteroidGO:003196010.024
chordate embryonic developmentGO:00430092710.024
extrinsic apoptotic signaling pathwayGO:009719130.024
guanosine containing compound catabolic processGO:190106920.024
compound eye developmentGO:004874920.024
meiotic cell cycle processGO:190304630.024
membrane fusionGO:006102520.024
regulation of protein import into nucleusGO:004230620.023
proteasomal protein catabolic processGO:001049820.023
regulation of erk1 and erk2 cascadeGO:007037240.023
autophagyGO:000691440.023
regulation of response to stimulusGO:00485832690.023
monoamine transportGO:001584410.023
cellular lipid catabolic processGO:004424230.023
modification dependent protein catabolic processGO:001994130.023
fatty acid catabolic processGO:000906210.023
regulation of programmed cell deathGO:00430671010.023
guanosine containing compound metabolic processGO:190106840.023
positive regulation of ras protein signal transductionGO:004657910.023
cellular component biogenesisGO:00440851780.023
cellular component movementGO:00069283350.022
negative regulation of programmed cell deathGO:0043069580.022
exocytosisGO:000688710.022
nucleic acid templated transcriptionGO:00976591810.022
membrane lipid biosynthetic processGO:004646720.022
regulation of blood pressureGO:000821710.022
positive regulation of catabolic processGO:000989640.022
positive regulation of cytokine productionGO:000181920.022
rna metabolic processGO:00160702190.022
regulation of cell activationGO:005086510.022
regulation of signalingGO:00230512350.022
positive regulation of cellular amine metabolic processGO:003324000.022
aromatic compound biosynthetic processGO:00194382170.021
positive regulation of cell activationGO:005086710.021
regulation of cell communicationGO:00106462320.021
positive regulation of secretionGO:005104710.021
positive regulation of map kinase activityGO:004340630.021
estrogen metabolic processGO:000821020.021
regulation of cellular amine metabolic processGO:003323800.021
regulation of purine nucleotide catabolic processGO:003312120.021
regulation of nucleocytoplasmic transportGO:004682220.021
nucleobase containing compound metabolic processGO:00061392740.021
cell surface receptor signaling pathwayGO:00071663250.021
regulation of protein targetingGO:190353320.021
response to glucocorticoidGO:005138410.021
cellular biosynthetic processGO:00442492860.021
protein heterooligomerizationGO:005129110.021
protein import into nucleusGO:000660630.020
response to uvGO:000941130.020
glial cell migrationGO:000834730.020
establishment of protein localization to organelleGO:007259440.020
protein localization to plasma membraneGO:007265910.020
eye developmentGO:00016542770.020
single organism nuclear importGO:190259330.020
regulation of nucleotide catabolic processGO:003081120.020
sphingolipid biosynthetic processGO:003014820.020
regulation of signal transductionGO:00099662250.020
reactive oxygen species biosynthetic processGO:190340910.020
negative regulation of nuclear divisionGO:005178430.020
cell morphogenesisGO:00009022890.020
monocarboxylic acid catabolic processGO:007232930.020
regulation of autophagyGO:001050630.020
single organism metabolic processGO:00447102170.020
regulation of cellular biosynthetic processGO:00313262450.020
positive regulation of apoptotic signaling pathwayGO:200123510.020
organic cyclic compound biosynthetic processGO:19013622230.020
negative regulation of cellular processGO:00485232830.020
central nervous system developmentGO:00074173870.019
leukocyte proliferationGO:007066110.019
cellular ketone metabolic processGO:0042180110.019
hemopoiesisGO:00300971830.019
regulation of nucleobase containing compound metabolic processGO:00192192500.019
regulation of developmental processGO:00507932470.019
gtp metabolic processGO:004603940.019
protein importGO:001703830.019
hepaticobiliary system developmentGO:0061008980.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
regulation of metabolic processGO:00192223590.019
regulation of cellular amino acid metabolic processGO:000652100.019
cellular component morphogenesisGO:00329893360.019
regulation of hormone secretionGO:004688320.018
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.018
secondary metabolic processGO:001974830.018
nuclear importGO:005117030.018
deathGO:00162651210.018
positive regulation of secretion by cellGO:190353210.018
regulation of primary metabolic processGO:00800903110.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
organic cyclic compound metabolic processGO:19013603010.018
positive regulation of immune effector processGO:000269930.018
regulation of macromolecule biosynthetic processGO:00105562250.018
protein secretionGO:000930610.018
regulation of macromolecule metabolic processGO:00602553170.018
regulation of tube sizeGO:003515020.018
protein homooligomerizationGO:005126030.018
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.018
rna 3 end processingGO:003112320.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
erk1 and erk2 cascadeGO:007037140.018
regulation of cellular metabolic processGO:00313233200.018
response to abiotic stimulusGO:00096281220.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
medulla oblongata developmentGO:002155040.017
maintenance of locationGO:005123540.017
cellular response to nutrient levelsGO:003166920.017
positive regulation of epithelial cell migrationGO:001063420.017
positive regulation of erk1 and erk2 cascadeGO:007037420.017
positive regulation of leukocyte mediated immunityGO:000270510.017
regulation of nitrogen compound metabolic processGO:00511712510.017
cell deathGO:00082191210.017
regulation of cysteine type endopeptidase activityGO:2000116210.017
lipid storageGO:001991510.017
single organism localizationGO:19025782250.017
peptide metabolic processGO:000651810.017
macromolecule biosynthetic processGO:00090592270.017
regulation of rna metabolic processGO:00512522240.017
single organism transportGO:00447652060.017
dorsal motor nucleus of vagus nerve developmentGO:002174440.016
g1 s transition of mitotic cell cycleGO:000008210.016
viral processGO:001603210.016
phosphatidylinositol 3 kinase signalingGO:001406520.016
ribonucleoside monophosphate catabolic processGO:000915840.016
embryo development ending in birth or egg hatchingGO:00097922710.016
stem cell fate commitmentGO:004886510.016
organic acid catabolic processGO:001605430.016
tube morphogenesisGO:00352393490.016
peptidyl serine phosphorylationGO:001810510.016
negative regulation of cytoplasmic transportGO:190365020.016
negative regulation of protein kinase activityGO:000646940.016
digestive tract developmentGO:00485652650.016
transcription from rna polymerase ii promoterGO:0006366800.016
regulation of protein catabolic processGO:004217610.016
protein k48 linked ubiquitinationGO:007093610.016
camera type eye developmentGO:00430102220.016
apoptotic processGO:00069151160.016
regulation of gtpase activityGO:004308720.016
neurotransmitter transportGO:000683620.016
regulation of gtp catabolic processGO:003312420.016
gene expressionGO:00104672520.016
digestive system developmentGO:00551232890.016
gtp catabolic processGO:000618420.016
positive regulation of nucleotide catabolic processGO:003081310.016
cellular macromolecule biosynthetic processGO:00346452240.016
organelle assemblyGO:00709251100.016
negative regulation of signalingGO:0023057960.016
myeloid cell differentiationGO:0030099860.015
production of molecular mediator of immune responseGO:000244020.015
brain developmentGO:00074202930.015
negative regulation of protein transportGO:005122430.015
neuron differentiationGO:00301823530.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
small molecule catabolic processGO:004428230.015
programmed cell deathGO:00125011190.015
meiosis iGO:000712710.015
phosphatidylinositol mediated signalingGO:004801520.015
intracellular signal transductionGO:0035556850.015
negative regulation of protein phosphorylationGO:000193340.015
regulation of heart growthGO:006042020.015
myeloid cell homeostasisGO:0002262560.015
regulation of cell deathGO:00109411030.015
stem cell proliferationGO:007208940.015
heart developmentGO:00075073130.015
regulation of wound healingGO:006104120.015
zymogen activationGO:003163830.015
generation of neuronsGO:00486993850.015
positive regulation of biological processGO:00485182530.015
response to hexoseGO:000974630.015
locomotionGO:00400113130.015
regulation of production of molecular mediator of immune responseGO:000270010.015
cellular response to extracellular stimulusGO:003166820.015
cellular localizationGO:0051641970.015
meiotic chromosome segregationGO:004513230.015
xenobiotic metabolic processGO:000680540.015
positive regulation of cell cycleGO:004578730.015
developmental programmed cell deathGO:001062340.015
response to external stimulusGO:00096052640.014
golgi vesicle transportGO:004819330.014
cellular modified amino acid metabolic processGO:000657530.014
adherens junction organizationGO:003433240.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
negative regulation of apoptotic processGO:0043066550.014
regulation of blood vessel sizeGO:005088020.014
regulation of reproductive processGO:200024140.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
negative regulation of cytokine productionGO:000181810.014
homeostatic processGO:00425921420.014
regulation of mrna processingGO:005068430.014
regulation of molecular functionGO:0065009700.014
peptide transportGO:001583310.014
growthGO:00400071740.014
regulation of biosynthetic processGO:00098892500.014
nucleoside monophosphate catabolic processGO:000912540.014
cellular response to hypoxiaGO:007145610.014
mononuclear cell proliferationGO:003294310.014
cellular nitrogen compound metabolic processGO:00346412900.014
negative regulation of kinase activityGO:003367340.014
purine nucleoside monophosphate catabolic processGO:000912840.014
positive regulation of cellular component biogenesisGO:004408930.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
regulation of reactive oxygen species metabolic processGO:200037720.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
immune system developmentGO:00025201910.014
cell motilityGO:00488702440.014
nuclear exportGO:005116810.014
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.014
cellular response to oxygen levelsGO:007145310.014
cytoskeleton organizationGO:0007010960.014
endosomal transportGO:001619720.014
regulation of organ growthGO:004662030.014
nucleic acid metabolic processGO:00903042440.013
response to copper ionGO:0046688130.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
transcription dna templatedGO:00063511810.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
epithelial tube morphogenesisGO:00605621480.013
cognitionGO:005089010.013
negative regulation of secretionGO:005104820.013
cellular component disassemblyGO:002241110.013
system processGO:00030081850.013
stem cell maintenanceGO:001982740.013
inositol lipid mediated signalingGO:004801720.013
positive regulation of glucose transportGO:001082810.013
liver developmentGO:0001889960.013
response to coldGO:000940940.013
regulation of carbohydrate metabolic processGO:000610940.013
ameboidal type cell migrationGO:00016671430.013
pole plasm assemblyGO:000731540.013
interspecies interaction between organismsGO:004441940.013
heterocycle biosynthetic processGO:00181302150.013
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.013
negative regulation of mapk cascadeGO:004340940.013
glucose importGO:004632320.013
transportGO:00068102200.013
head developmentGO:00603223030.013
cell junction maintenanceGO:003433120.013
leukocyte mediated cytotoxicityGO:000190910.013
negative regulation of cell communicationGO:0010648960.013
negative regulation of cell deathGO:0060548600.013
negative regulation of signal transductionGO:0009968940.013
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.013
regulation of dna replicationGO:000627530.013
phagocytosis engulfmentGO:000691110.013
establishment of localizationGO:00512342440.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
regulation of transcription dna templatedGO:00063552130.012
regulation of response to stressGO:0080134360.012
ovulation cycleGO:004269820.012
regulation of dna templated transcription in response to stressGO:004362000.012
homeostasis of number of cellsGO:0048872620.012
regulation of glucose transportGO:001082710.012
negative regulation of secretion by cellGO:190353120.012
cellular carbohydrate metabolic processGO:004426240.012
regulation of hematopoietic progenitor cell differentiationGO:190153210.012
macromolecule localizationGO:0033036540.012
response to monosaccharideGO:003428430.012
urogenital system developmentGO:0001655970.012
stem cell divisionGO:001714510.012
regulation of rho protein signal transductionGO:003502320.012
cellular response to chemical stimulusGO:00708871570.012
macromolecular complex subunit organizationGO:0043933740.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
establishment of protein localization to plasma membraneGO:009000210.012
regulation of cell shapeGO:000836010.012
ras protein signal transductionGO:000726570.012
lipid catabolic processGO:001604240.012
positive regulation of cell adhesionGO:004578510.012
regulation of systemic arterial blood pressureGO:000307310.012
lipid oxidationGO:003444010.012
cell death in response to oxidative stressGO:003647320.012
negative regulation of response to stimulusGO:00485851040.012
regulation of dendrite developmentGO:005077330.012
b cell activationGO:004211320.012
cell killingGO:000190620.012
negative regulation of synapse assemblyGO:005196420.012
regulation of oxidative stress induced cell deathGO:190320120.012
fatty acid biosynthetic processGO:000663340.012
regulation of gene expressionGO:00104682650.012
germ line stem cell maintenanceGO:003071820.012
regulation of apoptotic processGO:0042981980.012
phosphorus metabolic processGO:00067931090.012
cell cycle g1 s phase transitionGO:004484310.012
modification dependent macromolecule catabolic processGO:004363230.012
regulation of protein bindingGO:004339330.012
cellular transition metal ion homeostasisGO:004691630.012
response to vitaminGO:003327330.012
negative regulation of intracellular protein transportGO:009031730.012
hormone secretionGO:004687920.012
neutrophil mediated immunityGO:000244610.012
positive regulation of muscle tissue developmentGO:190186310.012
neuron neuron synaptic transmissionGO:000727010.012
catechol containing compound metabolic processGO:000971220.012
response to chemicalGO:00422213200.012
negative regulation of protein import into nucleusGO:004230820.012
locomotor rhythmGO:004547530.012
cofactor metabolic processGO:0051186150.012
innate immune responseGO:0045087130.012
female sex differentiationGO:004666040.012
cellular amide metabolic processGO:004360340.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
cellular response to starvationGO:000926710.012
regulation of mitochondrion organizationGO:001082110.012
primary neural tube formationGO:001402010.012
retina development in camera type eyeGO:00600411460.012
rna biosynthetic processGO:00327741810.012
eye morphogenesisGO:00485921440.012
regulation of peptidase activityGO:0052547230.012
regulation of glucose importGO:004632410.012
cell projection morphogenesisGO:00488582440.011
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.011
membrane invaginationGO:001032410.011
tube closureGO:006060610.011
rna localizationGO:000640340.011
antimicrobial humoral responseGO:001973020.011
lymphocyte proliferationGO:004665110.011
catecholamine biosynthetic processGO:004242320.011
single organism membrane fusionGO:004480120.011
cell projection organizationGO:00300302840.011
protein stabilizationGO:005082120.011
striated muscle cell differentiationGO:00511461290.011
regulation of response to oxidative stressGO:190288220.011
regulation of protein complex assemblyGO:004325430.011
regulation of transporter activityGO:003240920.011
regulation of endopeptidase activityGO:0052548230.011
protein polyubiquitinationGO:000020940.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
regulation of synaptic plasticityGO:004816710.011
positive regulation of gtpase activityGO:004354710.011
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.011
morphogenesis of an epithelial sheetGO:0002011490.011
iron ion homeostasisGO:005507240.011
negative regulation of signal transduction in absence of ligandGO:190109910.011
neurotransmitter secretionGO:000726920.011
renal system developmentGO:0072001940.011
cell migrationGO:00164772370.011
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.011
regulation of synapse assemblyGO:005196330.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.011
positive regulation of dna metabolic processGO:005105410.011
actin filament based processGO:0030029640.011
regulation of dna templated transcription elongationGO:003278430.011
spindle assemblyGO:005122520.011
cellular component maintenanceGO:004395430.011
sensory organ morphogenesisGO:00905962000.011
regulation of response to biotic stimulusGO:000283120.011
mrna 3 end processingGO:003112420.011
cell morphogenesis involved in differentiationGO:00009041950.011
negative regulation of mitosisGO:004583930.011
synaptic growth at neuromuscular junctionGO:005112420.011
response to organic substanceGO:00100331530.011
hormone transportGO:000991420.011
internal peptidyl lysine acetylationGO:001839320.011
negative regulation of catabolic processGO:000989530.011
regulation of protein ubiquitinationGO:003139630.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
cell part morphogenesisGO:00329902460.010
adherens junction maintenanceGO:003433420.010
kidney developmentGO:0001822920.010
i kappab kinase nf kappab signalingGO:000724940.010
cellular response to decreased oxygen levelsGO:003629410.010
regulation of stem cell differentiationGO:200073640.010
b cell differentiationGO:003018310.010
odontogenesis of dentin containing toothGO:004247510.010
multi organism cellular processGO:004476420.010
multicellular organismal response to stressGO:003355520.010
regulation of rna biosynthetic processGO:20011412130.010
muscle structure developmentGO:00610611960.010
negative regulation of map kinase activityGO:004340720.010
regulation of response to nutrient levelsGO:003210710.010
positive regulation of lymphocyte mediated immunityGO:000270810.010
protein complex subunit organizationGO:0071822460.010
negative regulation of intracellular transportGO:003238730.010
immune responseGO:0006955280.010
positive regulation of neuron deathGO:190121610.010
dna templated transcription elongationGO:000635430.010

nsdhl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.057
disease of metabolismDOID:001466700.024
nervous system diseaseDOID:86300.022
inherited metabolic disorderDOID:65500.022
organ system cancerDOID:005068600.020
cancerDOID:16200.020
disease of cellular proliferationDOID:1456600.020
musculoskeletal system diseaseDOID:1700.015
neurodegenerative diseaseDOID:128900.014
motor neuron diseaseDOID:23100.014
central nervous system diseaseDOID:33100.014
amyotrophic lateral sclerosisDOID:33200.014
connective tissue diseaseDOID:6500.013
bone diseaseDOID:008000100.013
mitochondrial metabolism diseaseDOID:70000.013
muscular diseaseDOID:008000000.010
cardiovascular system diseaseDOID:128700.010
heart diseaseDOID:11400.010
muscle tissue diseaseDOID:6600.010
cardiomyopathyDOID:005070000.010
myopathyDOID:42300.010