Danio rerio

37 known processes

nipblb

novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)

(Aliases: nipbl,wu:fi33d08)

nipblb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
specification of symmetryGO:00097992040.706
determination of bilateral symmetryGO:00098552040.681
embryonic organ morphogenesisGO:00485622740.651
regulation of response to stimulusGO:00485832690.576
regulation of cellular metabolic processGO:00313233200.574
embryonic organ developmentGO:00485683810.565
anterior posterior pattern specificationGO:00099521520.560
transcription dna templatedGO:00063511810.528
morphogenesis of an epitheliumGO:00020093330.488
digestive system developmentGO:00551232890.418
hindbrain developmentGO:0030902910.413
kupffer s vesicle developmentGO:0070121500.392
mechanosensory lateral line system developmentGO:0048881490.389
regulation of gene expressionGO:00104682650.385
determination of heart left right asymmetryGO:00613711170.370
regulation of transcription dna templatedGO:00063552130.358
embryonic heart tube morphogenesisGO:00031431080.346
neuromast primordium migrationGO:0048883120.333
brain developmentGO:00074202930.333
determination of left right symmetryGO:00073681790.329
transcription from rna polymerase ii promoterGO:0006366800.325
organic cyclic compound biosynthetic processGO:19013622230.312
regulation of rna metabolic processGO:00512522240.306
posterior lateral line developmentGO:0048916380.305
organic cyclic compound metabolic processGO:19013603010.295
deathGO:00162651210.293
cellular nitrogen compound biosynthetic processGO:00442712180.293
digestive tract developmentGO:00485652650.290
nucleic acid metabolic processGO:00903042440.285
tube morphogenesisGO:00352393490.283
rna metabolic processGO:00160702190.281
alcohol biosynthetic processGO:004616520.279
diencephalon developmentGO:0021536580.274
positive regulation of cellular processGO:00485222010.273
aromatic compound biosynthetic processGO:00194382170.266
heart joggingGO:0003146400.265
signal transductionGO:00071654550.261
biosynthetic processGO:00090582940.260
mesenchyme developmentGO:00604851270.260
regulation of axon extensionGO:0030516240.254
rna biosynthetic processGO:00327741810.253
macromolecule biosynthetic processGO:00090592270.253
regionalizationGO:00030022740.246
hematopoietic or lymphoid organ developmentGO:00485341910.246
cell migrationGO:00164772370.244
regulation of signalingGO:00230512350.240
regulation of epithelial cell proliferationGO:005067830.239
posterior lateral line system developmentGO:0048915460.237
inner ear receptor cell developmentGO:0060119200.234
nucleobase containing compound biosynthetic processGO:00346542050.232
cell surface receptor signaling pathwayGO:00071663250.229
enzyme linked receptor protein signaling pathwayGO:00071671060.222
dorsal ventral pattern formationGO:00099531250.214
immune system processGO:00023762410.214
pituitary gland developmentGO:0021983160.213
organic substance biosynthetic processGO:19015762890.209
regulation of nucleobase containing compound metabolic processGO:00192192500.209
heterocycle biosynthetic processGO:00181302150.208
regulation of primary metabolic processGO:00800903110.205
larval developmentGO:000216420.204
cellular aromatic compound metabolic processGO:00067252950.203
hemopoiesisGO:00300971830.197
rhombomere 5 developmentGO:002157140.191
embryonic pattern specificationGO:0009880440.187
embryonic heart tube developmentGO:00350501330.184
regulation of signal transductionGO:00099662250.183
head developmentGO:00603223030.175
maintenance of locationGO:005123540.173
regulation of cell differentiationGO:00455951420.172
regulation of macromolecule biosynthetic processGO:00105562250.171
liver developmentGO:0001889960.170
connective tissue developmentGO:0061448990.168
regulation of neuron differentiationGO:0045664560.163
immune responseGO:0006955280.162
retina morphogenesis in camera type eyeGO:0060042790.161
rhombomere 6 developmentGO:002157240.160
negative regulation of biological processGO:00485193040.159
regulation of multicellular organismal developmentGO:20000262230.156
digestive tract morphogenesisGO:00485462310.154
regulation of axonogenesisGO:0050770320.154
regulation of transcription from rna polymerase ii promoterGO:00063571140.148
lateral line system developmentGO:0048925760.145
immune system developmentGO:00025201910.145
cellular macromolecule metabolic processGO:00442603910.144
developmental growth involved in morphogenesisGO:0060560860.140
positive regulation of nervous system developmentGO:0051962250.140
kidney developmentGO:0001822920.139
regulation of cell communicationGO:00106462320.139
cellular nitrogen compound metabolic processGO:00346412900.137
inner ear developmentGO:00488391260.137
cellular macromolecule biosynthetic processGO:00346452240.136
generation of neuronsGO:00486993850.134
rhombomere developmentGO:0021546190.133
negative regulation of cellular processGO:00485232830.133
regulation of nucleic acid templated transcriptionGO:19035062130.133
central nervous system developmentGO:00074173870.129
hair cell differentiationGO:0035315320.126
regulation of macromolecule metabolic processGO:00602553170.125
gland developmentGO:00487321430.120
cell fate commitmentGO:0045165990.119
blood vessel morphogenesisGO:00485142160.119
otic vesicle developmentGO:0071599420.118
heart developmentGO:00075073130.117
specification of organ identityGO:001009220.116
tissue remodelingGO:004877140.114
programmed cell deathGO:00125011190.114
cartilage developmentGO:0051216960.113
nitrogen compound metabolic processGO:00068073190.111
lateral line developmentGO:0048882660.111
cell migration involved in gastrulationGO:0042074790.108
response to chemicalGO:00422213200.108
double strand break repairGO:000630230.107
wnt signaling pathwayGO:0016055800.104
ear morphogenesisGO:0042471640.103
hepaticobiliary system developmentGO:0061008980.102
regulation of immune system processGO:0002682340.101
locomotionGO:00400113130.101
epithelial cell differentiationGO:00308551160.100
regulation of rna biosynthetic processGO:20011412130.100
response to stressGO:00069502630.099
urogenital system developmentGO:0001655970.098
regulation of cellular macromolecule biosynthetic processGO:20001122220.098
homeostatic processGO:00425921420.097
single organism metabolic processGO:00447102170.097
tissue regenerationGO:0042246740.095
regulation of cellular biosynthetic processGO:00313262450.095
cellular component morphogenesisGO:00329893360.094
nephron morphogenesisGO:007202820.094
mesoderm developmentGO:0007498880.091
positive regulation of biological processGO:00485182530.091
regulation of nitrogen compound metabolic processGO:00511712510.090
regulation of organ morphogenesisGO:2000027350.088
regulation of developmental processGO:00507932470.088
single organism organelle organizationGO:19025891990.086
cellular biosynthetic processGO:00442492860.085
skeletal system developmentGO:00015011810.084
regulation of biosynthetic processGO:00098892500.082
hard palate developmentGO:006002240.082
sensory organ developmentGO:00074233930.081
cell motilityGO:00488702440.079
renal system developmentGO:0072001940.079
transmission of nerve impulseGO:0019226190.078
otic placode formationGO:0043049230.077
regulation of neurogenesisGO:0050767870.077
vasculature developmentGO:00019442780.076
eye morphogenesisGO:00485921440.076
developmental inductionGO:0031128100.075
forebrain developmentGO:0030900960.075
inner ear morphogenesisGO:0042472630.074
heterocycle metabolic processGO:00464832900.074
ectodermal placode morphogenesisGO:0071697320.073
steroid metabolic processGO:000820270.073
localization of cellGO:00516742440.072
canonical wnt signaling pathwayGO:0060070480.071
axon extensionGO:0048675450.071
nucleobase containing compound metabolic processGO:00061392740.070
stem cell differentiationGO:00488631170.069
cellular response to endogenous stimulusGO:0071495680.069
negative regulation of programmed cell deathGO:0043069580.068
spemann organizer formationGO:0060061100.068
regulation of cell developmentGO:00602841000.066
myeloid cell differentiationGO:0030099860.066
epithelial tube morphogenesisGO:00605621480.066
activin receptor signaling pathwayGO:003292480.066
epidermal cell differentiationGO:0009913360.065
regulation of canonical wnt signaling pathwayGO:0060828340.065
positive regulation of gene expressionGO:0010628710.065
negative regulation of transcription dna templatedGO:0045892450.065
bmp signaling pathwayGO:0030509520.064
positive regulation of response to stimulusGO:0048584800.063
positive regulation of rna metabolic processGO:0051254590.063
regulation of apoptotic processGO:0042981980.062
epidermis developmentGO:0008544480.062
camera type eye developmentGO:00430102220.061
camera type eye morphogenesisGO:00485931080.061
heart loopingGO:0001947940.060
positive regulation of cell divisionGO:005178120.060
regulation of cell divisionGO:0051302120.060
peripheral nervous system developmentGO:0007422550.059
regulation of cell deathGO:00109411030.059
developmental growthGO:00485891660.058
response to organic substanceGO:00100331530.058
neuron differentiationGO:00301823530.058
lipid storageGO:001991510.058
protein metabolic processGO:00195381830.058
inner ear receptor cell differentiationGO:0060113290.057
phosphorus metabolic processGO:00067931090.057
phagocytosisGO:000690930.056
defense response to other organismGO:0098542330.056
erythrocyte differentiationGO:0030218540.056
somite developmentGO:0061053960.055
eye developmentGO:00016542770.055
cellular component movementGO:00069283350.055
multicellular organism growthGO:003526440.055
sensory system developmentGO:0048880760.053
angiogenesisGO:00015251580.053
positive regulation of transportGO:005105020.053
regulation of programmed cell deathGO:00430671010.053
organelle organizationGO:00069962270.052
negative regulation of cell deathGO:0060548600.052
embryonic retina morphogenesis in camera type eyeGO:0060059220.052
lipid metabolic processGO:0006629520.051
fibroblast growth factor receptor signaling pathwayGO:0008543220.051
muscle structure developmentGO:00610611960.051
regulation of wnt signaling pathwayGO:0030111530.050
skin developmentGO:0043588540.050
small molecule metabolic processGO:0044281770.050
regulation of multicellular organismal processGO:00512392770.050
axis elongationGO:0003401310.049
protein k48 linked ubiquitinationGO:007093610.049
fin developmentGO:0033333770.048
steroid hormone mediated signaling pathwayGO:004340190.048
negative regulation of nucleic acid templated transcriptionGO:1903507450.048
pancreas developmentGO:0031016840.048
endocrine system developmentGO:0035270650.048
sensory organ morphogenesisGO:00905962000.047
protein modification processGO:00362111000.047
positive regulation of cellular catabolic processGO:003133130.046
fin regenerationGO:0031101510.046
cellular response to growth factor stimulusGO:0071363390.046
response to endogenous stimulusGO:0009719830.045
ectodermal placode developmentGO:0071696370.045
positive regulation of transcription dna templatedGO:0045893570.045
negative regulation of gene expressionGO:0010629650.045
gene expressionGO:00104672520.044
neuron projection extensionGO:1990138450.044
positive regulation of nitrogen compound metabolic processGO:0051173690.044
regulation of nervous system developmentGO:0051960900.044
somitogenesisGO:0001756870.044
growthGO:00400071740.044
ear developmentGO:00435831270.044
regulation of response to external stimulusGO:0032101310.044
regulation of immune responseGO:0050776140.043
otic vesicle formationGO:0030916270.043
glial cell differentiationGO:0010001420.043
renal tubule morphogenesisGO:006133310.043
ameboidal type cell migrationGO:00016671430.043
pectoral fin developmentGO:0033339500.042
regulation of chemotaxisGO:0050920180.042
mesenchymal cell developmentGO:0014031780.041
negative regulation of response to stimulusGO:00485851040.041
developmental cell growthGO:0048588520.041
cell projection morphogenesisGO:00488582440.041
cell growthGO:0016049570.041
regulation of cellular component movementGO:0051270550.041
ovulation cycleGO:004269820.041
female gonad developmentGO:000858540.041
b cell activationGO:004211320.040
midbrain developmentGO:0030901280.040
erythrocyte homeostasisGO:0034101550.040
cellular response to stressGO:0033554620.040
bone remodelingGO:004684920.040
regulation of metabolic processGO:00192223590.040
appendage developmentGO:0048736800.039
muscle fiber developmentGO:0048747520.039
stem cell maintenanceGO:001982740.039
multicellular organismal signalingGO:0035637220.039
morphogenesis of a branching structureGO:0001763210.038
endosome to lysosome transportGO:000833310.038
b cell mediated immunityGO:001972430.038
otolith developmentGO:0048840320.038
steroid biosynthetic processGO:000669450.037
cell morphogenesis involved in differentiationGO:00009041950.037
nephron epithelium morphogenesisGO:007208810.037
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.037
guanosine containing compound catabolic processGO:190106920.036
myeloid cell developmentGO:0061515320.036
ovarian follicle developmentGO:000154120.036
retina development in camera type eyeGO:00600411460.036
cardiac atrium developmentGO:000323040.036
axon extension involved in axon guidanceGO:0048846100.036
negative regulation of apoptotic processGO:0043066550.036
chordate embryonic developmentGO:00430092710.036
fin morphogenesisGO:0033334530.036
dna catabolic processGO:000630810.035
anatomical structure homeostasisGO:0060249360.035
regulation of biological qualityGO:00650082630.035
humoral immune response mediated by circulating immunoglobulinGO:000245530.035
ovulation cycle processGO:002260220.035
establishment of localizationGO:00512342440.035
positive regulation of nucleic acid templated transcriptionGO:1903508570.034
neural nucleus developmentGO:0048857150.034
cilium morphogenesisGO:0060271850.034
cell cell signaling involved in cell fate commitmentGO:0045168120.034
germ line stem cell maintenanceGO:003071820.033
multicellular organism reproductionGO:0032504350.033
positive regulation of rna biosynthetic processGO:1902680570.032
cell morphogenesisGO:00009022890.032
mechanoreceptor differentiationGO:0042490370.032
regenerationGO:0031099910.032
embryonic hemopoiesisGO:0035162530.032
myeloid cell homeostasisGO:0002262560.032
peptide metabolic processGO:000651810.032
female sex differentiationGO:004666040.031
positive regulation of biosynthetic processGO:0009891680.031
regulation of mesoderm developmentGO:2000380110.030
anterior posterior axis specificationGO:0009948200.030
muscle cell differentiationGO:00426921390.030
nephron tubule morphogenesisGO:007207810.030
pectoral fin morphogenesisGO:0035138290.030
tube closureGO:006060610.030
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.030
neuron developmentGO:00486662620.030
regulation of locomotionGO:0040012550.030
immunoglobulin mediated immune responseGO:001606430.030
regulation of cell motilityGO:2000145460.030
respiratory system developmentGO:006054150.030
cell cycle processGO:0022402530.030
regulation of growthGO:0040008420.030
cellular response to organic substanceGO:00713101050.029
regulation of protein transportGO:005122330.029
oligodendrocyte differentiationGO:0048709230.028
positive regulation of cellular metabolic processGO:0031325940.028
determination of left right asymmetry in diencephalonGO:003546240.028
regulation of oocyte developmentGO:006028130.028
spermatid developmentGO:000728620.028
pons developmentGO:0021548110.028
response to fluid shear stressGO:003440520.028
response to growth factorGO:0070848390.028
response to abiotic stimulusGO:00096281220.028
granulocyte chemotaxisGO:0071621110.028
regulation of bindingGO:005109830.028
organ formationGO:0048645170.028
regulation of nucleoside metabolic processGO:000911820.028
nephron developmentGO:0072006310.028
positive regulation of cellular component movementGO:0051272110.027
wnt signaling pathway planar cell polarity pathwayGO:006007140.027
regulation of calcium dependent cell cell adhesionGO:004658610.027
striated muscle cell differentiationGO:00511461290.027
locus ceruleus developmentGO:002170330.027
phosphate containing compound metabolic processGO:00067961080.027
positive regulation of immune system processGO:0002684170.027
hematopoietic progenitor cell differentiationGO:0002244230.027
positive regulation of cellular biosynthetic processGO:0031328680.027
neuron fate commitmentGO:0048663260.027
cell projection organizationGO:00300302840.027
regulation of axon guidanceGO:190266780.027
positive regulation of macromolecule biosynthetic processGO:0010557590.027
nephron epithelium developmentGO:0072009160.026
lipid biosynthetic processGO:0008610220.026
cellular response to fibroblast growth factor stimulusGO:0044344220.026
positive regulation of neuron apoptotic processGO:004352510.026
blood vessel developmentGO:00015682460.026
negative regulation of cellular biosynthetic processGO:0031327550.026
response to external biotic stimulusGO:0043207970.026
regulation of establishment of planar polarityGO:009017540.026
erk1 and erk2 cascadeGO:007037140.026
positive regulation of catabolic processGO:000989640.026
single organism biosynthetic processGO:0044711710.026
neuronal action potentialGO:0019228180.025
negative regulation of signalingGO:0023057960.025
regulation of cell proliferationGO:0042127370.024
positive regulation of lipid metabolic processGO:004583410.024
negative regulation of cell communicationGO:0010648960.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.024
cellular protein modification processGO:00064641000.024
leukocyte chemotaxisGO:0030595120.024
regulation of alcohol biosynthetic processGO:190293010.024
chromatin modificationGO:0016568210.023
positive regulation of erk1 and erk2 cascadeGO:007037420.023
metencephalon developmentGO:0022037270.023
gliogenesisGO:0042063450.023
vestibular receptor cell developmentGO:006011830.023
cell cycleGO:0007049930.023
rna localizationGO:000640340.023
mesenchymal cell differentiationGO:0048762870.023
primary neural tube formationGO:001402010.022
positive regulation of nucleobase containing compound metabolic processGO:0045935690.022
intracellular receptor signaling pathwayGO:0030522300.022
negative regulation of nodal signaling pathwayGO:190010840.022
response to external stimulusGO:00096052640.022
regulation of neuron projection developmentGO:0010975400.022
cellular response to chemical stimulusGO:00708871570.022
palate developmentGO:006002180.022
regulation of behaviorGO:0050795240.022
development of primary female sexual characteristicsGO:004654540.022
regulation of vasculature developmentGO:1901342330.021
nucleic acid templated transcriptionGO:00976591810.021
positive regulation of bmp signaling pathwayGO:0030513100.021
cellular respirationGO:004533330.021
mediolateral intercalationGO:006003130.021
regulation of multicellular organism growthGO:004001440.021
vestibular receptor cell differentiationGO:006011430.021
regulation of tissue remodelingGO:003410320.021
gastrulationGO:00073692080.021
regulation of nodal signaling pathwayGO:190010740.021
determination of left right asymmetry in lateral mesodermGO:0003140200.021
regulation of cell cycleGO:0051726520.021
negative regulation of wnt signaling pathwayGO:0030178300.021
protein phosphorylationGO:0006468470.021
g1 s transition of mitotic cell cycleGO:000008210.021
response to other organismGO:0051707970.021
negative regulation of metabolic processGO:0009892860.021
regulation of cell migrationGO:0030334400.021
regulation of wnt signaling pathway planar cell polarity pathwayGO:200009520.020
intracellular signal transductionGO:0035556850.020
cell deathGO:00082191210.020
negative regulation of nitrogen compound metabolic processGO:0051172590.020
cellular response to drugGO:003569010.020
wound healingGO:0042060900.020
embryonic appendage morphogenesisGO:0035113300.020
embryonic cranial skeleton morphogenesisGO:0048701900.020
single organism reproductive processGO:0044702400.020
nuclear transportGO:005116940.020
regulation of cell growthGO:0001558290.020
negative regulation of macromolecule metabolic processGO:0010605760.020
kidney epithelium developmentGO:0072073230.020
positive regulation of cell communicationGO:0010647560.020
positive regulation of cell cycleGO:004578730.020
regulation of cell morphogenesis involved in differentiationGO:0010769380.019
smooth muscle contractionGO:000693920.019
response to heatGO:000940860.019
convergent extensionGO:00600261180.019
otic vesicle morphogenesisGO:0071600340.019
embryonic skeletal system morphogenesisGO:0048704930.019
glucose homeostasisGO:004259310.019
regulation of anatomical structure morphogenesisGO:00226031300.019
regulation of biomineral tissue developmentGO:007016720.019
hormone transportGO:000991420.019
positive regulation of neural precursor cell proliferationGO:200017910.018
cell part morphogenesisGO:00329902460.018
regulation of erythrocyte differentiationGO:004564620.018
macromolecule modificationGO:00434121110.018
homeostasis of number of cellsGO:0048872620.018
regulation of blood vessel sizeGO:005088020.018
positive regulation of epithelial cell proliferationGO:005067910.018
response to temperature stimulusGO:0009266150.018
establishment of protein localization to plasma membraneGO:009000210.018
neuron projection developmentGO:00311751800.018
pericardium developmentGO:006003910.018
regulation of establishment of protein localizationGO:007020140.018
regulation of bmp signaling pathwayGO:0030510390.018
negative regulation of cell projection organizationGO:003134590.018
negative regulation of mesodermal cell fate specificationGO:004266230.018
glycolipid metabolic processGO:000666480.018
positive regulation of cell differentiationGO:0045597300.018
appendage morphogenesisGO:0035107560.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.018
endosomal transportGO:001619720.018
positive regulation of developmental processGO:0051094500.017
iron ion homeostasisGO:005507240.017
endodermal cell fate determinationGO:000749320.017
regulation of reproductive processGO:200024140.017
regulation of bone remodelingGO:004685020.017
adult behaviorGO:003053420.017
cilium assemblyGO:0042384580.017
positive regulation of muscle cell differentiationGO:005114910.017
negative regulation of signal transductionGO:0009968940.017
regulation of intracellular protein transportGO:003315730.017
primitive hemopoiesisGO:0060215270.017
positive regulation of macromolecule metabolic processGO:0010604930.017
negative regulation of multicellular organismal processGO:0051241690.017
regulation of meiotic cell cycleGO:005144510.016
regulation of stem cell differentiationGO:200073640.016
positive regulation of neurogenesisGO:0050769240.016
regulation of nucleocytoplasmic transportGO:004682220.016
regulation of purine nucleotide catabolic processGO:003312120.016
regulation of reactive oxygen species metabolic processGO:200037720.016
axonogenesisGO:00074091520.016
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.016
mitotic cell cycleGO:0000278640.016
b cell differentiationGO:003018310.016
positive regulation of signalingGO:0023056560.016
septum transversum developmentGO:000334340.016
positive regulation of neuron deathGO:190121610.016
hormone secretionGO:004687920.016
agingGO:000756820.016
heart morphogenesisGO:00030071560.016
cellular component disassemblyGO:002241110.016
cell cell signalingGO:0007267520.016
single organism localizationGO:19025782250.015
negative regulation of cellular metabolic processGO:0031324770.015
membrane invaginationGO:001032410.015
stem cell divisionGO:001714510.015
neuron projection extension involved in neuron projection guidanceGO:1902284100.015
granulocyte migrationGO:0097530110.015
regulation of angiogenesisGO:0045765260.015
retinoic acid receptor signaling pathwayGO:0048384160.015
positive regulation of cell developmentGO:0010720250.015
skeletal system morphogenesisGO:00487051020.015
innate immune responseGO:0045087130.015
response to fibroblast growth factorGO:0071774220.015
cilium movement involved in cell motilityGO:006029430.014
intracellular mrna localizationGO:000829810.014
regulation of cytokine productionGO:000181730.014
regulation of developmental growthGO:0048638380.014
nuclear exportGO:005116810.014
regulation of dna recombinationGO:000001820.014
somatic stem cell maintenanceGO:003501910.014
bone morphogenesisGO:0060349110.014
positive regulation of metabolic processGO:00098931080.014

nipblb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
nervous system diseaseDOID:86300.026
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.019
organ system cancerDOID:005068600.019