Danio rerio

0 known processes

hps1

Hermansky-Pudlak syndrome 1

(Aliases: MGC123240,im:7143944,zgc:123240)

hps1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to stressGO:00069502630.075
Mouse
cellular biosynthetic processGO:00442492860.071
response to external stimulusGO:00096052640.071
response to drugGO:004249330.069
response to chemicalGO:00422213200.067
cellular aromatic compound metabolic processGO:00067252950.067
nucleobase containing compound metabolic processGO:00061392740.064
biosynthetic processGO:00090582940.062
organic substance biosynthetic processGO:19015762890.058
regulation of nucleobase containing compound metabolic processGO:00192192500.057
aromatic compound biosynthetic processGO:00194382170.056
cellular nitrogen compound metabolic processGO:00346412900.052
chordate embryonic developmentGO:00430092710.051
heterocycle metabolic processGO:00464832900.050
organic cyclic compound metabolic processGO:19013603010.049
nucleic acid metabolic processGO:00903042440.049
nitrogen compound metabolic processGO:00068073190.049
cellular macromolecule metabolic processGO:00442603910.047
neuron differentiationGO:00301823530.046
positive regulation of transportGO:005105020.045
cellular response to external stimulusGO:007149620.045
single organism metabolic processGO:00447102170.042
determination of left right symmetryGO:00073681790.040
negative regulation of cellular processGO:00485232830.040
organic cyclic compound biosynthetic processGO:19013622230.040
regulation of synapse organizationGO:005080730.037
immune system processGO:00023762410.037
Mouse
apoptotic processGO:00069151160.037
tube morphogenesisGO:00352393490.037
brain developmentGO:00074202930.035
rna metabolic processGO:00160702190.035
regulation of synaptic plasticityGO:004816710.035
amine metabolic processGO:000930820.035
mitochondrion organizationGO:000700540.035
negative regulation of biological processGO:00485193040.034
small molecule metabolic processGO:0044281770.034
nucleobase containing compound biosynthetic processGO:00346542050.034
regulation of multicellular organism growthGO:004001440.034
adult behaviorGO:003053420.033
determination of bilateral symmetryGO:00098552040.033
single organism nuclear importGO:190259330.033
heterocycle biosynthetic processGO:00181302150.033
digestive system developmentGO:00551232890.032
agingGO:000756820.032
protein targeting to nucleusGO:004474430.032
cellular nitrogen compound biosynthetic processGO:00442712180.032
negative regulation of kinase activityGO:003367340.032
regulation of gene expressionGO:00104682650.032
gtp metabolic processGO:004603940.031
autophagyGO:000691440.031
maintenance of locationGO:005123540.031
positive regulation of cellular component biogenesisGO:004408930.031
fat soluble vitamin metabolic processGO:000677540.031
response to organic substanceGO:00100331530.030
rna biosynthetic processGO:00327741810.030
carboxylic acid metabolic processGO:0019752220.030
multicellular organism growthGO:003526440.030
signal transductionGO:00071654550.030
response to nutrientGO:000758430.029
central nervous system developmentGO:00074173870.029
eye developmentGO:00016542770.029
Mouse
regulation of cellular biosynthetic processGO:00313262450.029
cellular component morphogenesisGO:00329893360.029
cellular response to nutrient levelsGO:003166920.029
neuron developmentGO:00486662620.028
nuclear transportGO:005116940.028
phosphorus metabolic processGO:00067931090.028
larval developmentGO:000216420.028
regulation of nitrogen compound metabolic processGO:00511712510.028
regulation of biological qualityGO:00650082630.027
Mouse
gene expressionGO:00104672520.027
establishment of protein localization to organelleGO:007259440.027
vitamin a metabolic processGO:000677610.027
embryonic organ developmentGO:00485683810.027
positive regulation of catabolic processGO:000989640.027
system processGO:00030081850.027
digestive tract developmentGO:00485652650.027
pancreas developmentGO:0031016840.027
cellular response to extracellular stimulusGO:003166820.027
regulation of autophagyGO:001050630.027
cognitionGO:005089010.027
cellular response to radiationGO:007147840.027
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
regulation of inflammatory responseGO:005072720.026
guanosine containing compound catabolic processGO:190106920.026
alpha amino acid metabolic processGO:190160530.026
positive regulation of cell cycleGO:004578730.026
nucleic acid templated transcriptionGO:00976591810.026
lipid storageGO:001991510.025
cellular protein catabolic processGO:004425740.025
regulation of signalingGO:00230512350.025
regulation of response to stimulusGO:00485832690.025
cellular amino acid metabolic processGO:000652070.025
single organism biosynthetic processGO:0044711710.025
regulation of cell communicationGO:00106462320.025
organonitrogen compound metabolic processGO:1901564740.024
blood circulationGO:0008015870.024
negative regulation of catabolic processGO:000989530.024
response to glucocorticoidGO:005138410.024
response to corticosteroidGO:003196010.023
positive regulation of cellular catabolic processGO:003133130.023
regulation of macromolecule biosynthetic processGO:00105562250.023
transcription dna templatedGO:00063511810.023
neurotransmitter transportGO:000683620.023
regulation of primary metabolic processGO:00800903110.023
regulation of cellular metabolic processGO:00313233200.023
cellular response to chemical stimulusGO:00708871570.023
response to external biotic stimulusGO:0043207970.023
nuclear importGO:005117030.023
regulation of macromolecule metabolic processGO:00602553170.023
embryo development ending in birth or egg hatchingGO:00097922710.023
generation of neuronsGO:00486993850.023
digestive tract morphogenesisGO:00485462310.022
response to lipidGO:0033993600.022
negative regulation of protein kinase activityGO:000646940.022
guanosine containing compound metabolic processGO:190106840.022
nucleocytoplasmic transportGO:000691340.022
regulation of nucleoside metabolic processGO:000911820.022
regulation of reproductive processGO:200024140.022
organic acid metabolic processGO:0006082310.022
negative regulation of cellular catabolic processGO:003133030.021
response to light stimulusGO:0009416460.021
head developmentGO:00603223030.021
cellular macromolecule biosynthetic processGO:00346452240.021
regulation of purine nucleotide catabolic processGO:003312120.021
proteolysis involved in cellular protein catabolic processGO:005160330.021
response to hydrogen peroxideGO:004254230.021
phototransductionGO:000760220.021
multi organism processGO:00517041340.021
response to uvGO:000941130.021
meiotic cell cycle processGO:190304630.021
neuroblast proliferationGO:000740520.021
oxoacid metabolic processGO:0043436310.021
regulation of apoptotic processGO:0042981980.021
membrane fusionGO:006102520.021
deathGO:00162651210.020
specification of symmetryGO:00097992040.020
negative regulation of sequestering of calcium ionGO:005128340.020
regulation of protein catabolic processGO:004217610.020
morphogenesis of an epitheliumGO:00020093330.020
regulation of nucleotide catabolic processGO:003081120.020
regulation of blood pressureGO:000821710.020
locomotionGO:00400113130.020
cellular component movementGO:00069283350.020
protein import into nucleusGO:000660630.019
regulation of cell activationGO:005086510.019
Mouse
embryonic heart tube developmentGO:00350501330.019
cellular response to oxygen levelsGO:007145310.019
transportGO:00068102200.019
Mouse
intracellular receptor signaling pathwayGO:0030522300.019
cellular response to starvationGO:000926710.019
negative regulation of protein phosphorylationGO:000193340.019
neurotransmitter secretionGO:000726920.019
regulation of signal transductionGO:00099662250.018
cellular amine metabolic processGO:004410620.018
phosphate containing compound metabolic processGO:00067961080.018
response to biotic stimulusGO:0009607970.018
circulatory system processGO:0003013870.018
neuron neuron synaptic transmissionGO:000727010.018
stem cell proliferationGO:007208940.018
cellular aldehyde metabolic processGO:000608140.018
gtp catabolic processGO:000618420.018
response to vitaminGO:003327330.017
meiotic nuclear divisionGO:000712640.017
cellular component assembly involved in morphogenesisGO:00109271070.017
response to organic cyclic compoundGO:0014070510.017
regulation of tube sizeGO:003515020.017
ubiquitin dependent protein catabolic processGO:000651130.017
cellular hormone metabolic processGO:0034754190.017
synaptic vesicle transportGO:004848910.017
cell part morphogenesisGO:00329902460.017
macroautophagyGO:001623610.017
sensory perception of painGO:001923310.017
positive regulation of biological processGO:00485182530.017
Mouse
positive regulation of purine nucleotide catabolic processGO:003312310.017
i kappab kinase nf kappab signalingGO:000724940.017
cellular response to organic substanceGO:00713101050.017
regulation of multicellular organismal processGO:00512392770.017
regulation of transcription dna templatedGO:00063552130.017
phagocytosisGO:000690930.017
regulation of response to extracellular stimulusGO:003210410.017
peptide transportGO:001583310.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
hematopoietic or lymphoid organ developmentGO:00485341910.016
cell cycle g1 s phase transitionGO:004484310.016
regulation of gtpase activityGO:004308720.016
cellular response to stressGO:0033554620.016
cellular ketone metabolic processGO:0042180110.016
multicellular organismal response to stressGO:003355520.016
regulation of dendrite developmentGO:005077330.016
protein metabolic processGO:00195381830.016
synaptic growth at neuromuscular junctionGO:005112420.016
regulation of blood vessel sizeGO:005088020.016
tissue remodelingGO:004877140.016
immune system developmentGO:00025201910.016
stem cell maintenanceGO:001982740.016
protein importGO:001703830.016
regulation of programmed cell deathGO:00430671010.016
positive regulation of nucleotide catabolic processGO:003081310.016
regulation of metal ion transportGO:001095940.016
embryonic organ morphogenesisGO:00485622740.016
regulation of cytokine productionGO:000181730.016
cortical cytoskeleton organizationGO:003086510.016
organelle organizationGO:00069962270.016
Mouse
regulation of cytoplasmic transportGO:190364940.016
epithelial tube morphogenesisGO:00605621480.016
positive regulation of secretionGO:005104710.016
diterpenoid metabolic processGO:0016101150.016
chemosensory behaviorGO:000763510.016
positive regulation of inflammatory responseGO:005072910.016
cortical actin cytoskeleton organizationGO:003086610.016
regulation of biosynthetic processGO:00098892500.016
response to alkaloidGO:004327920.016
cell projection organizationGO:00300302840.016
proteasomal protein catabolic processGO:001049820.016
regulation of synapse assemblyGO:005196330.016
mesenchyme developmentGO:00604851270.016
synaptic vesicle localizationGO:009747910.015
single organism transportGO:00447652060.015
Mouse
regulation of metabolic processGO:00192223590.015
organelle fusionGO:004828430.015
modification dependent macromolecule catabolic processGO:004363230.015
response to carbohydrateGO:000974330.015
cytoskeleton dependent cytokinesisGO:006164030.015
locomotor rhythmGO:004547530.015
homeostatic processGO:00425921420.015
heart developmentGO:00075073130.015
post golgi vesicle mediated transportGO:000689210.015
positive regulation of cell activationGO:005086710.015
Mouse
sensory organ developmentGO:00074233930.015
Mouse
cellular modified amino acid metabolic processGO:000657530.015
programmed cell deathGO:00125011190.015
sensory perception of chemical stimulusGO:000760630.015
cellular response to light stimulusGO:007148240.015
hindbrain developmentGO:0030902910.015
response to radiationGO:0009314510.015
anterior posterior pattern specificationGO:00099521520.015
double strand break repairGO:000630230.015
axon ensheathment in central nervous systemGO:003229120.015
localization of cellGO:00516742440.015
regulation of bindingGO:005109830.015
positive regulation of nucleoside metabolic processGO:004597910.015
response to abiotic stimulusGO:00096281220.015
single organism organelle organizationGO:19025891990.014
modification dependent protein catabolic processGO:001994130.014
regulation of rna biosynthetic processGO:20011412130.014
heart contractionGO:0060047710.014
response to other organismGO:0051707970.014
alcohol biosynthetic processGO:004616520.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
regulation of gtp catabolic processGO:003312420.014
spermatid developmentGO:000728620.014
hemopoiesisGO:00300971830.014
regulation of calcium ion transportGO:005192420.014
eye morphogenesisGO:00485921440.014
regulation of cellular amine metabolic processGO:003323800.014
positive regulation of gtp catabolic processGO:003312610.014
regulation of protein transportGO:005122330.014
cell morphogenesisGO:00009022890.014
response to endogenous stimulusGO:0009719830.014
photoreceptor cell differentiationGO:0046530550.014
response to inorganic substanceGO:0010035380.014
terpenoid metabolic processGO:0006721150.014
regulation of nervous system developmentGO:0051960900.014
melanin metabolic processGO:000658220.014
regulation of cell deathGO:00109411030.014
positive regulation of synapse assemblyGO:005196510.014
hormone secretionGO:004687920.014
macromolecule modificationGO:00434121110.014
regulation of response to nutrient levelsGO:003210710.014
regulation of cellular ketone metabolic processGO:001056570.014
regulation of developmental processGO:00507932470.014
cellular response to biotic stimulusGO:007121630.014
axon developmentGO:00615641660.013
g1 s transition of mitotic cell cycleGO:000008210.013
regulation of muscle contractionGO:000693730.013
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.013
response to monosaccharideGO:003428430.013
cellular protein metabolic processGO:00442671290.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
negative regulation of cellular metabolic processGO:0031324770.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
regulation of neural precursor cell proliferationGO:200017730.013
regulation of intracellular protein transportGO:003315730.013
lipid oxidationGO:003444010.013
lipid metabolic processGO:0006629520.013
spermatid differentiationGO:004851520.013
cellular response to decreased oxygen levelsGO:003629410.013
response to woundingGO:00096111160.013
Mouse
stem cell divisionGO:001714510.013
regulation of cell differentiationGO:00455951420.013
protein modification processGO:00362111000.013
positive regulation of secretion by cellGO:190353210.013
protein localization to nucleusGO:003450430.013
myeloid cell differentiationGO:0030099860.013
camera type eye developmentGO:00430102220.013
Mouse
regulation of establishment of protein localizationGO:007020140.013
wound healingGO:0042060900.013
Mouse
regulation of protein complex assemblyGO:004325430.013
positive regulation of cellular processGO:00485222010.013
Mouse
hormone transportGO:000991420.013
organophosphate biosynthetic processGO:0090407230.013
pigmentationGO:0043473850.013
Mouse
cell projection morphogenesisGO:00488582440.012
lipid homeostasisGO:005508830.012
macromolecule biosynthetic processGO:00090592270.012
cytokinesisGO:000091030.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
response to hexoseGO:000974630.012
membrane invaginationGO:001032410.012
cell morphogenesis involved in differentiationGO:00009041950.012
purine nucleoside monophosphate catabolic processGO:000912840.012
cell migrationGO:00164772370.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
oxidation reduction processGO:0055114410.012
response to ketoneGO:190165410.012
regulation of protein bindingGO:004339330.012
negative regulation of programmed cell deathGO:0043069580.012
regulation of sequestering of calcium ionGO:005128240.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
organophosphate metabolic processGO:0019637370.012
response to oxygen levelsGO:0070482250.012
rna localizationGO:000640340.012
retinoid metabolic processGO:0001523150.012
single fertilizationGO:000733830.012
regulation of organ growthGO:004662030.012
regulation of cellular amino acid metabolic processGO:000652100.012
small molecule catabolic processGO:004428230.012
response to glucoseGO:000974930.012
exocytosisGO:000688710.012
phototransduction visible lightGO:000760320.012
positive regulation of gtpase activityGO:004354710.012
regulation of cell projection assemblyGO:006049140.012
regulation of neuronal synaptic plasticityGO:004816810.011
central nervous system myelinationGO:002201020.011
regulation of neurotransmitter transportGO:005158810.011
b cell activationGO:004211320.011
regulation of localizationGO:00328791040.011
heart processGO:0003015710.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
action potentialGO:0001508190.011
actin mediated cell contractionGO:007025210.011
monoamine transportGO:001584410.011
fat soluble vitamin biosynthetic processGO:004236220.011
intracellular signal transductionGO:0035556850.011
growthGO:00400071740.011
regenerationGO:0031099910.011
cell substrate adhesionGO:003158940.011
blood vessel morphogenesisGO:00485142160.011
regulation of dendrite morphogenesisGO:004881430.011
regulation of molecular functionGO:0065009700.011
behaviorGO:0007610740.011
regulation of systemic arterial blood pressureGO:000307310.011
axonogenesisGO:00074091520.011
cellular amino acid biosynthetic processGO:000865220.011
positive regulation of immune effector processGO:000269930.011
response to amino acidGO:004320020.011
establishment of synaptic vesicle localizationGO:009748010.011
cellular protein modification processGO:00064641000.011
alcohol metabolic processGO:0006066110.011
muscle cell developmentGO:00550011150.011
carbohydrate homeostasisGO:003350010.011
regulation of ion transmembrane transporter activityGO:003241220.011
mononuclear cell proliferationGO:003294310.011
cell surface receptor signaling pathwayGO:00071663250.011
cellular component assemblyGO:00226071700.011
cytosolic calcium ion transportGO:006040130.011
regulation of multicellular organismal developmentGO:20000262230.011
positive regulation of blood circulationGO:190352420.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
regulation of circadian rhythmGO:004275240.011
heart loopingGO:0001947940.011
regulation of multicellular organismal metabolic processGO:004424620.011
organic substance transportGO:0071702580.011
Mouse
striated muscle cell developmentGO:00550021080.010
cell deathGO:00082191210.010
inositol lipid mediated signalingGO:004801720.010
fertilizationGO:000956630.010
cell proliferationGO:0008283800.010
positive regulation of lymphocyte mediated immunityGO:000270810.010
cellular response to molecule of bacterial originGO:007121930.010
enzyme linked receptor protein signaling pathwayGO:00071671060.010
response to hormoneGO:0009725480.010
protein polymerizationGO:005125840.010
establishment of protein localization to plasma membraneGO:009000210.010
protein localization to plasma membraneGO:007265910.010
tissue regenerationGO:0042246740.010
cellular lipid catabolic processGO:004424230.010
carboxylic acid catabolic processGO:004639530.010
negative regulation of cell communicationGO:0010648960.010
macromolecular complex disassemblyGO:003298410.010
positive regulation of cytoskeleton organizationGO:005149530.010
organelle assemblyGO:00709251100.010
negative regulation of apoptotic processGO:0043066550.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.010
retina development in camera type eyeGO:00600411460.010
Mouse

hps1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
nervous system diseaseDOID:86300.026
eye and adnexa diseaseDOID:149200.026
sensory system diseaseDOID:005015500.026
eye diseaseDOID:561400.026
disease of metabolismDOID:001466700.021
musculoskeletal system diseaseDOID:1700.020
retinitis pigmentosaDOID:1058400.015
retinal degenerationDOID:846600.015
retinal diseaseDOID:567900.015
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
cancerDOID:16200.013
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.012
inherited metabolic disorderDOID:65500.011