Danio rerio

85 known processes

myst3

MYST histone acetyltransferase (monocytic leukemia) 3

(Aliases: moz,bmd)

myst3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic skeletal system morphogenesisGO:0048704930.103
larval developmentGO:000216420.094
cellular protein catabolic processGO:004425740.094
regulation of response to stimulusGO:00485832690.090
eye developmentGO:00016542770.089
signal transductionGO:00071654550.083
regulation of signal transductionGO:00099662250.083
embryo development ending in birth or egg hatchingGO:00097922710.079
nucleocytoplasmic transportGO:000691340.077
sensory organ developmentGO:00074233930.076
phagocytosisGO:000690930.067
blood vessel developmentGO:00015682460.063
Mouse
nuclear transportGO:005116940.062
regulation of stem cell proliferationGO:007209120.060
regulation of protein catabolic processGO:004217610.059
neuron differentiationGO:00301823530.058
cell surface receptor signaling pathwayGO:00071663250.054
negative regulation of signal transductionGO:0009968940.054
ubiquitin dependent protein catabolic processGO:000651130.054
response to chemicalGO:00422213200.053
modification dependent protein catabolic processGO:001994130.052
regulation of metabolic processGO:00192223590.051
Mouse
regulation of signalingGO:00230512350.050
positive regulation of catabolic processGO:000989640.050
embryonic cranial skeleton morphogenesisGO:0048701900.049
stem cell proliferationGO:007208940.048
generation of neuronsGO:00486993850.048
endosomal transportGO:001619720.046
regulation of cell communicationGO:00106462320.046
regulation of nucleocytoplasmic transportGO:004682220.046
negative regulation of cell communicationGO:0010648960.046
nitrogen compound metabolic processGO:00068073190.045
Mouse
cell morphogenesisGO:00009022890.045
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.045
proteolysis involved in cellular protein catabolic processGO:005160330.043
cell projection morphogenesisGO:00488582440.043
lipid storageGO:001991510.043
regulation of neurogenesisGO:0050767870.043
neuron projection developmentGO:00311751800.043
positive regulation of transportGO:005105020.042
regulation of nervous system developmentGO:0051960900.042
regulation of synaptic growth at neuromuscular junctionGO:000858210.042
maintenance of locationGO:005123540.042
brain developmentGO:00074202930.042
cellular component morphogenesisGO:00329893360.042
embryonic viscerocranium morphogenesisGO:0048703520.041
regulation of cytokine productionGO:000181730.041
meiotic nuclear divisionGO:000712640.040
guanosine containing compound metabolic processGO:190106840.040
negative regulation of cellular processGO:00485232830.039
Mouse
regulation of establishment of protein localizationGO:007020140.039
modification dependent macromolecule catabolic processGO:004363230.038
establishment of protein localization to organelleGO:007259440.038
embryonic organ morphogenesisGO:00485622740.038
camera type eye developmentGO:00430102220.038
embryonic organ developmentGO:00485683810.037
skeletal system developmentGO:00015011810.036
response to stressGO:00069502630.036
regulation of synapse organizationGO:005080730.036
single organism transportGO:00447652060.036
regulation of epithelial cell proliferationGO:005067830.036
negative regulation of response to stimulusGO:00485851040.035
single organism nuclear importGO:190259330.035
cell morphogenesis involved in differentiationGO:00009041950.035
b cell activationGO:004211320.034
agingGO:000756820.034
skeletal muscle organ developmentGO:0060538780.034
guanosine containing compound catabolic processGO:190106920.034
regulation of protein transportGO:005122330.034
cellular component movementGO:00069283350.034
chordate embryonic developmentGO:00430092710.034
heart developmentGO:00075073130.034
Mouse
protein import into nucleusGO:000660630.033
stem cell maintenanceGO:001982740.033
Mouse
regionalizationGO:00030022740.033
gene expressionGO:00104672520.033
Mouse
negative regulation of signalingGO:0023057960.033
positive regulation of mesenchymal cell proliferationGO:000205310.033
neuron developmentGO:00486662620.033
single organism metabolic processGO:00447102170.033
meiotic cell cycle processGO:190304630.033
cartilage developmentGO:0051216960.032
gtp metabolic processGO:004603940.032
regulation of wnt signaling pathwayGO:0030111530.032
gtp catabolic processGO:000618420.032
proteasomal protein catabolic processGO:001049820.032
embryonic skeletal system developmentGO:0048706970.031
positive regulation of cellular processGO:00485222010.031
macromolecule biosynthetic processGO:00090592270.031
Mouse
protein targeting to nucleusGO:004474430.031
cellular response to molecule of bacterial originGO:007121930.031
positive regulation of cellular catabolic processGO:003133130.031
regulation of cell differentiationGO:00455951420.031
Mouse
b cell differentiationGO:003018310.031
biosynthetic processGO:00090582940.031
Mouse
organic acid metabolic processGO:0006082310.030
locomotionGO:00400113130.030
connective tissue developmentGO:0061448990.030
transportGO:00068102200.030
regulation of multicellular organismal processGO:00512392770.030
regulation of synaptic plasticityGO:004816710.030
sensory organ morphogenesisGO:00905962000.029
protein localization to nucleusGO:003450430.029
cell projection organizationGO:00300302840.029
regulation of multicellular organism growthGO:004001440.029
single organism localizationGO:19025782250.029
head developmentGO:00603223030.028
Mouse
rna localizationGO:000640340.028
multicellular organism growthGO:003526440.028
regulation of nucleoside metabolic processGO:000911820.028
adult behaviorGO:003053420.028
response to external stimulusGO:00096052640.027
meiotic chromosome segregationGO:004513230.027
regulation of intracellular protein transportGO:003315730.027
tube morphogenesisGO:00352393490.027
regulation of cytoplasmic transportGO:190364940.027
regulation of cell activationGO:005086510.027
positive regulation of cell activationGO:005086710.027
mononuclear cell proliferationGO:003294310.026
protein importGO:001703830.026
negative regulation of protein phosphorylationGO:000193340.026
system processGO:00030081850.026
hatchingGO:003518840.026
rna transportGO:005065820.026
positive regulation of stem cell proliferationGO:200064810.026
axonogenesisGO:00074091520.025
hormone secretionGO:004687920.025
nuclear importGO:005117030.025
vasculature developmentGO:00019442780.025
Mouse
regulation of synapse assemblyGO:005196330.025
cellular localizationGO:0051641970.025
axon developmentGO:00615641660.025
sympathetic nervous system developmentGO:004848530.025
regulation of macromolecule metabolic processGO:00602553170.025
Mouse
female sex differentiationGO:004666040.025
establishment of localization in cellGO:0051649770.025
central nervous system developmentGO:00074173870.025
organism emergence from protective structureGO:007168440.024
cellular response to extracellular stimulusGO:003166820.024
cellular nitrogen compound metabolic processGO:00346412900.024
Mouse
organelle organizationGO:00069962270.024
eye morphogenesisGO:00485921440.024
negative regulation of cytokine productionGO:000181810.024
regulation of protein ubiquitinationGO:003139630.024
nucleic acid metabolic processGO:00903042440.024
Mouse
notochord morphogenesisGO:0048570170.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.024
regulation of cellular protein catabolic processGO:190336210.024
peptidyl serine phosphorylationGO:001810510.024
regulation of protein modification by small protein conjugation or removalGO:190332030.024
regulation of protein import into nucleusGO:004230620.024
programmed cell deathGO:00125011190.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.023
Mouse
golgi vesicle transportGO:004819330.023
cellular amide metabolic processGO:004360340.023
intracellular signal transductionGO:0035556850.023
protein metabolic processGO:00195381830.023
cellular response to lipopolysaccharideGO:007122230.023
cell morphogenesis involved in neuron differentiationGO:00486671630.023
heterocycle metabolic processGO:00464832900.023
Mouse
regulation of multicellular organismal developmentGO:20000262230.023
cellular macromolecule metabolic processGO:00442603910.023
internal peptidyl lysine acetylationGO:001839320.022
regulation of blood pressureGO:000821710.022
positive regulation of epithelial cell proliferationGO:005067910.022
regulation of macromolecule biosynthetic processGO:00105562250.022
Mouse
negative regulation of catabolic processGO:000989530.022
regulation of purine nucleotide catabolic processGO:003312120.022
regulation of reactive oxygen species metabolic processGO:200037720.022
neuron projection morphogenesisGO:00488121610.022
neuronal action potentialGO:0019228180.022
angiogenesisGO:00015251580.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.022
digestive system developmentGO:00551232890.022
cognitionGO:005089010.022
establishment of localizationGO:00512342440.022
regulation of nucleotide catabolic processGO:003081120.022
cellular response to biotic stimulusGO:007121630.022
compound eye developmentGO:004874920.022
striated muscle tissue developmentGO:00147061100.022
lymphocyte proliferationGO:004665110.021
muscle tissue developmentGO:00605371100.021
negative regulation of epithelial cell proliferationGO:005068010.021
cilium morphogenesisGO:0060271850.021
anterior posterior pattern specificationGO:00099521520.021
action potentialGO:0001508190.021
neuroblast proliferationGO:000740520.021
organonitrogen compound metabolic processGO:1901564740.021
cellular response to nutrient levelsGO:003166920.021
regulation of production of molecular mediator of immune responseGO:000270010.021
phagocytosis engulfmentGO:000691110.020
enzyme linked receptor protein signaling pathwayGO:00071671060.020
cell part morphogenesisGO:00329902460.020
transcription dna templatedGO:00063511810.020
Mouse
lens development in camera type eyeGO:0002088220.020
regulation of gtp catabolic processGO:003312420.020
negative regulation of biological processGO:00485193040.020
Mouse
regulation of neural precursor cell proliferationGO:200017730.020
regulation of protein localization to nucleusGO:190018020.020
mesenchyme developmentGO:00604851270.020
rhombomere 5 developmentGO:002157140.020
positive regulation of small gtpase mediated signal transductionGO:005105710.020
leukocyte differentiationGO:0002521250.020
multicellular organismal signalingGO:0035637220.020
cell motilityGO:00488702440.019
antimicrobial humoral responseGO:001973020.019
leukocyte proliferationGO:007066110.019
glial cell migrationGO:000834730.019
locomotor rhythmGO:004547530.019
sequestering of calcium ionGO:005120830.019
regulation of anatomical structure morphogenesisGO:00226031300.019
negative regulation of synapse assemblyGO:005196420.019
amine metabolic processGO:000930820.019
synaptic vesicle transportGO:004848910.019
nucleic acid templated transcriptionGO:00976591810.019
Mouse
positive regulation of cellular component biogenesisGO:004408930.019
apoptotic processGO:00069151160.019
cell deathGO:00082191210.019
membrane invaginationGO:001032410.019
regulation of protein targetingGO:190353320.019
single fertilizationGO:000733830.019
response to organic substanceGO:00100331530.019
retina development in camera type eyeGO:00600411460.019
wnt signaling pathwayGO:0016055800.019
central nervous system myelin formationGO:003228910.019
primary neural tube formationGO:001402010.018
cellular carbohydrate metabolic processGO:004426240.018
lipid homeostasisGO:005508830.018
mechanosensory lateral line system developmentGO:0048881490.018
cellular ketone metabolic processGO:0042180110.018
regulation of apoptotic processGO:0042981980.018
regulation of cellular amine metabolic processGO:003323800.018
positive regulation of myeloid cell differentiationGO:004563920.018
organelle localizationGO:0051640490.018
positive regulation of cellular amine metabolic processGO:003324000.018
multi organism processGO:00517041340.018
phosphatidylinositol mediated signalingGO:004801520.018
protein dephosphorylationGO:000647030.018
regulation of systemic arterial blood pressureGO:000307310.018
cellular response to starvationGO:000926710.018
regulation of stem cell differentiationGO:200073640.018
muscle structure developmentGO:00610611960.018
chemosensory behaviorGO:000763510.017
nuclear exportGO:005116810.017
digestive tract developmentGO:00485652650.017
organic cyclic compound metabolic processGO:19013603010.017
Mouse
regulation of nitrogen compound metabolic processGO:00511712510.017
Mouse
sensory system developmentGO:0048880760.017
oocyte maturationGO:000155640.017
multi organism cellular processGO:004476420.017
negative regulation of cellular catabolic processGO:003133030.017
liver developmentGO:0001889960.017
synaptic vesicle localizationGO:009747910.017
cranial ganglion developmentGO:006155030.017
tube closureGO:006060610.017
regulation of myotube differentiationGO:001083020.017
cellular component disassemblyGO:002241110.017
cellular amine metabolic processGO:004410620.017
protein heterooligomerizationGO:005129110.016
tissue remodelingGO:004877140.016
regulation of reproductive processGO:200024140.016
gastrulationGO:00073692080.016
rna 3 end processingGO:003112320.016
regulation of cell shapeGO:000836010.016
skeletal muscle tissue developmentGO:0007519670.016
neuron neuron synaptic transmissionGO:000727010.016
negative regulation of chromosome organizationGO:200125110.016
lateral line system developmentGO:0048925760.016
determination of left right symmetryGO:00073681790.016
nucleic acid transportGO:005065720.016
regulation of biosynthetic processGO:00098892500.016
Mouse
positive regulation of cytokine productionGO:000181920.016
regenerationGO:0031099910.016
regulation of dendrite developmentGO:005077330.016
blood vessel morphogenesisGO:00485142160.016
Mouse
synaptic growth at neuromuscular junctionGO:005112420.016
response to drugGO:004249330.016
regulation of rna biosynthetic processGO:20011412130.016
Mouse
vacuolar transportGO:000703420.016
cellular protein metabolic processGO:00442671290.016
cellular nitrogen compound biosynthetic processGO:00442712180.016
Mouse
skeletal system morphogenesisGO:00487051020.016
protein acylationGO:004354330.016
positive regulation of biological processGO:00485182530.016
cell migrationGO:00164772370.016
macromolecule localizationGO:0033036540.016
transmission of nerve impulseGO:0019226190.016
phosphatidylinositol 3 kinase signalingGO:001406520.016
positive regulation of signal transductionGO:0009967560.016
cellular response to external stimulusGO:007149620.016
female gonad developmentGO:000858540.016
small molecule metabolic processGO:0044281770.015
regulation of bindingGO:005109830.015
regulation of biological qualityGO:00650082630.015
extrinsic apoptotic signaling pathwayGO:009719130.015
positive regulation of ras protein signal transductionGO:004657910.015
peptidyl lysine acetylationGO:001839420.015
internal protein amino acid acetylationGO:000647520.015
pigmentationGO:0043473850.015
positive regulation of immune effector processGO:000269930.015
cellular component assembly involved in morphogenesisGO:00109271070.015
lateral inhibitionGO:004633110.015
epithelial cell differentiationGO:00308551160.015
cellular response to chemical stimulusGO:00708871570.015
catecholamine metabolic processGO:000658420.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
positive regulation of secretionGO:005104710.015
regulation of gene expressionGO:00104682650.015
Mouse
rna metabolic processGO:00160702190.015
Mouse
camera type eye morphogenesisGO:00485931080.015
i kappab kinase nf kappab signalingGO:000724940.015
regulation of cellular component sizeGO:0032535300.015
positive regulation of endothelial cell proliferationGO:000193810.015
positive regulation of cell cycleGO:004578730.015
regulation of mesenchymal cell proliferationGO:001046410.015
regulation of developmental processGO:00507932470.015
Mouse
diencephalon developmentGO:0021536580.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
neurotransmitter transportGO:000683620.015
somatic muscle developmentGO:000752540.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
Mouse
establishment of synaptic vesicle localizationGO:009748010.015
muscle cell developmentGO:00550011150.015
catechol containing compound metabolic processGO:000971220.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
Mouse
stem cell divisionGO:001714510.014
single organism organelle organizationGO:19025891990.014
digestive tract morphogenesisGO:00485462310.014
regulation of meiotic cell cycleGO:005144510.014
regulation of rna metabolic processGO:00512522240.014
Mouse
immune system developmentGO:00025201910.014
Mouse
posterior lateral line developmentGO:0048916380.014
regulation of organelle assemblyGO:190211540.014
regulation of primary metabolic processGO:00800903110.014
Mouse
response to woundingGO:00096111160.014
oxoacid metabolic processGO:0043436310.014
actin polymerization or depolymerizationGO:000815420.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
deathGO:00162651210.014
carbohydrate biosynthetic processGO:001605110.014
peptidyl serine modificationGO:001820920.014
autophagyGO:000691440.014
cellular protein modification processGO:00064641000.014
cellular component assemblyGO:00226071700.014
production of molecular mediator of immune responseGO:000244020.014
carboxylic acid metabolic processGO:0019752220.014
localization of cellGO:00516742440.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
morphogenesis of an epitheliumGO:00020093330.014
regulation of inflammatory responseGO:005072720.014
posterior lateral line system developmentGO:0048915460.014
erk1 and erk2 cascadeGO:007037140.014
regulation of neuron differentiationGO:0045664560.014
chromatin modificationGO:0016568210.014
response to carbohydrateGO:000974330.014
periodic partitioningGO:000736510.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
single organism membrane fusionGO:004480120.014
histone deacetylationGO:001657520.014
histone h3 k4 methylationGO:005156820.014
positive regulation of dna templated transcription elongationGO:003278610.014
cellular response to organic substanceGO:00713101050.014
mechanosensory behaviorGO:000763820.014
canonical wnt signaling pathwayGO:0060070480.014
regulation of cellular ketone metabolic processGO:001056570.014
aromatic compound biosynthetic processGO:00194382170.014
Mouse
regulation of response to biotic stimulusGO:000283120.013
peptide transportGO:001583310.013
autonomic nervous system developmentGO:0048483190.013
proximal distal pattern formationGO:000995410.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
response to topologically incorrect proteinGO:003596620.013
mesenchymal cell differentiationGO:0048762870.013
regulation of dna templated transcription elongationGO:003278430.013
atp catabolic processGO:000620040.013
positive regulation of secretion by cellGO:190353210.013
microtubule organizing center organizationGO:003102310.013
synaptic vesicle recyclingGO:003646510.013
retina morphogenesis in camera type eyeGO:0060042790.013
positive regulation of nucleoside metabolic processGO:004597910.013
axon guidanceGO:0007411860.013
microtubule based processGO:0007017600.013
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.013
regulation of cell developmentGO:00602841000.013
cilium organizationGO:0044782710.013
ribonucleoside monophosphate catabolic processGO:000915840.013
regulation of sequestering of calcium ionGO:005128240.013
protein acetylationGO:000647320.013
establishment of rna localizationGO:005123630.013
carbohydrate homeostasisGO:003350010.013
fertilizationGO:000956630.013
peptide metabolic processGO:000651810.013
negative regulation of leukocyte differentiationGO:190210610.013
intracellular mrna localizationGO:000829810.013
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.013
negative regulation of protein kinase activityGO:000646940.013
sensory perception of chemical stimulusGO:000760630.013
g2 m transition of mitotic cell cycleGO:000008640.013
positive regulation of cell communicationGO:0010647560.013
positive regulation of epithelial cell migrationGO:001063420.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
positive regulation of gtp catabolic processGO:003312610.013
cellular response to radiationGO:007147840.013
stem cell developmentGO:0048864820.013
positive regulation of metabolic processGO:00098931080.013
regulation of cell projection assemblyGO:006049140.013
negative regulation of protein transportGO:005122430.013
interspecies interaction between organismsGO:004441940.013
behaviorGO:0007610740.013
mrna transportGO:005102820.012
peptidyl threonine phosphorylationGO:001810710.012
ventricular cardiac muscle tissue morphogenesisGO:005501020.012
cell cycle arrestGO:000705010.012
hormone transportGO:000991420.012
cellular response to stressGO:0033554620.012
positive regulation of nucleotide catabolic processGO:003081310.012
mitochondrion organizationGO:000700540.012
negative regulation of defense responseGO:003134820.012
g protein coupled receptor signaling pathwayGO:0007186740.012
synaptic vesicle endocytosisGO:004848810.012
protein homooligomerizationGO:005126030.012
outflow tract morphogenesisGO:000315110.012
regulation of cell deathGO:00109411030.012
cellular amino acid metabolic processGO:000652070.012
positive regulation of gtpase activityGO:004354710.012
cellular aromatic compound metabolic processGO:00067252950.012
Mouse
facial nerve developmentGO:002156130.012
negative regulation of mapk cascadeGO:004340940.012
negative regulation of metabolic processGO:0009892860.012
cytosolic calcium ion transportGO:006040130.012
response to oxygen containing compoundGO:1901700550.012
negative regulation of myeloid cell differentiationGO:004563810.012
negative regulation of secretionGO:005104820.012
protein complex disassemblyGO:004324110.012
ras protein signal transductionGO:000726570.012
positive regulation of notch signaling pathwayGO:004574730.012
central nervous system myelinationGO:002201020.012
macromolecular complex disassemblyGO:003298410.012
regulation of ras gtpase activityGO:003231820.012
cellular component biogenesisGO:00440851780.012
mesenchymal cell developmentGO:0014031780.012
regulation of rho protein signal transductionGO:003502320.012
negative regulation of kinase activityGO:003367340.012
regulation of endothelial cell proliferationGO:000193610.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
rna export from nucleusGO:000640510.012
small gtpase mediated signal transductionGO:000726480.012
photoreceptor cell differentiationGO:0046530550.012
positive regulation of epithelial cell differentiationGO:003085820.012
developmental growthGO:00485891660.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
Mouse
positive regulation of cytoskeleton organizationGO:005149530.012
positive regulation of cellular biosynthetic processGO:0031328680.012
multicellular organismal metabolic processGO:004423620.012
regulation of erk1 and erk2 cascadeGO:007037240.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
regulation of protein metabolic processGO:0051246560.012
taxisGO:00423301090.011
post embryonic organ developmentGO:004856940.011
gland developmentGO:00487321430.011
response to endogenous stimulusGO:0009719830.011
protein stabilizationGO:005082120.011
negative regulation of ras protein signal transductionGO:004658010.011
maternal determination of anterior posterior axis embryoGO:000835840.011
forebrain cell migrationGO:002188510.011
negative regulation of sequestering of calcium ionGO:005128340.011
regulation of cellular metabolic processGO:00313233200.011
Mouse
regulation of cellular biosynthetic processGO:00313262450.011
Mouse
negative regulation of secretion by cellGO:190353120.011
cell projection assemblyGO:0030031640.011
olfactory lobe developmentGO:002198840.011
nucleobase containing compound transportGO:001593120.011
embryonic skeletal joint developmentGO:007249830.011
organic substance biosynthetic processGO:19015762890.011
Mouse
axon ensheathment in central nervous systemGO:003229120.011
multicellular organismal response to stressGO:003355520.011
mrna export from nucleusGO:000640610.011
mitochondrial transportGO:000683920.011
g1 s transition of mitotic cell cycleGO:000008210.011
secondary metabolic processGO:001974830.011
membrane fusionGO:006102520.011
cellular lipid catabolic processGO:004424230.011
segmentationGO:0035282970.011
exocytosisGO:000688710.011
dna templated transcription elongationGO:000635430.011
neuromast developmentGO:0048884460.011
g2 dna damage checkpointGO:003157230.011
somite developmentGO:0061053960.011

myst3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
musculoskeletal system diseaseDOID:1700.014
disease of anatomical entityDOID:700.014
organ system cancerDOID:005068600.013
cardiovascular system diseaseDOID:128700.012
disease of metabolismDOID:001466700.011