Danio rerio

5 known processes

pdhb

pyruvate dehydrogenase (lipoamide) beta

(Aliases: wu:fc76a05,zgc:64062)

pdhb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.603
Worm
atp synthesis coupled electron transportGO:004277310.593
respiratory electron transport chainGO:002290420.570
small molecule metabolic processGO:0044281770.461
Human Yeast
electron transport chainGO:002290020.392
cellular respirationGO:004533330.374
Human
mitochondrial atp synthesis coupled electron transportGO:004277510.340
ion transportGO:00068111140.320
phosphorus metabolic processGO:00067931090.319
Human Yeast
oxidative phosphorylationGO:000611910.310
single organism metabolic processGO:00447102170.309
purine containing compound biosynthetic processGO:0072522200.271
larval developmentGO:000216420.269
organonitrogen compound metabolic processGO:1901564740.215
ribonucleotide metabolic processGO:0009259270.204
organophosphate biosynthetic processGO:0090407230.195
nucleobase containing compound metabolic processGO:00061392740.173
organic cyclic compound metabolic processGO:19013603010.161
signal transductionGO:00071654550.148
organic cyclic compound biosynthetic processGO:19013622230.145
oxoacid metabolic processGO:0043436310.126
Human Yeast
embryo development ending in birth or egg hatchingGO:00097922710.121
Worm
organic acid metabolic processGO:0006082310.116
Human Yeast
cell part morphogenesisGO:00329902460.116
nucleobase containing small molecule metabolic processGO:0055086320.110
response to chemicalGO:00422213200.107
regulation of metabolic processGO:00192223590.101
transmembrane transportGO:00550851200.099
transportGO:00068102200.092
carbohydrate derivative metabolic processGO:1901135610.089
nitrogen compound metabolic processGO:00068073190.085
response to stressGO:00069502630.084
regulation of biological qualityGO:00650082630.081
organic substance biosynthetic processGO:19015762890.080
Human Yeast
single organism localizationGO:19025782250.078
cellular nitrogen compound metabolic processGO:00346412900.077
phosphate containing compound metabolic processGO:00067961080.074
locomotionGO:00400113130.072
carboxylic acid metabolic processGO:0019752220.069
Human Yeast
organelle organizationGO:00069962270.068
cellular component morphogenesisGO:00329893360.066
biosynthetic processGO:00090582940.066
Human Yeast
purine containing compound metabolic processGO:0072521290.065
female gamete generationGO:0007292140.064
cellular nitrogen compound biosynthetic processGO:00442712180.063
pigmentationGO:0043473850.063
carbohydrate derivative biosynthetic processGO:1901137430.063
nucleoside monophosphate catabolic processGO:000912540.062
pyruvate metabolic processGO:000609010.061
Human Yeast
single organism transportGO:00447652060.058
ribonucleoside monophosphate catabolic processGO:000915840.058
heterocycle biosynthetic processGO:00181302150.058
organophosphate metabolic processGO:0019637370.057
macromolecular complex subunit organizationGO:0043933740.057
behaviorGO:0007610740.057
digestive system developmentGO:00551232890.056
multicellular organism reproductionGO:0032504350.054
nucleoside metabolic processGO:0009116110.054
multicellular organism growthGO:003526440.053
heterocycle metabolic processGO:00464832900.052
purine ribonucleotide metabolic processGO:0009150270.052
spermatid differentiationGO:004851520.052
purine ribonucleoside monophosphate catabolic processGO:000916940.051
cellular aromatic compound metabolic processGO:00067252950.049
multi organism processGO:00517041340.049
multicellular organismal reproductive processGO:0048609350.049
atp catabolic processGO:000620040.049
mitochondrion organizationGO:000700540.048
gamete generationGO:0007276330.048
maintenance of locationGO:005123540.048
cellular biosynthetic processGO:00442492860.047
Human Yeast
cellular amino acid metabolic processGO:000652070.047
nucleotide metabolic processGO:0009117280.045
apoptotic processGO:00069151160.045
germ cell developmentGO:0007281220.045
purine nucleoside monophosphate catabolic processGO:000912840.044
cation transportGO:0006812810.044
cellular process involved in reproduction in multicellular organismGO:0022412280.043
establishment of localizationGO:00512342440.043
response to external stimulusGO:00096052640.043
digestive tract developmentGO:00485652650.042
system processGO:00030081850.042
reproductive processGO:0022414400.042
regulation of multicellular organism growthGO:004001440.041
phagocytosisGO:000690930.041
ribonucleotide biosynthetic processGO:0009260200.041
response to drugGO:004249330.041
stem cell proliferationGO:007208940.040
ribose phosphate metabolic processGO:0019693270.039
spermatid developmentGO:000728620.038
cellular component assemblyGO:00226071700.038
tube morphogenesisGO:00352393490.038
amine metabolic processGO:000930820.038
cellular protein complex assemblyGO:0043623190.037
cell surface receptor signaling pathwayGO:00071663250.037
liver developmentGO:0001889960.036
sexual reproductionGO:0019953360.036
organic acid catabolic processGO:001605430.034
ion transmembrane transportGO:0034220910.034
nucleoside phosphate metabolic processGO:0006753280.033
cellular amine metabolic processGO:004410620.033
inorganic cation transmembrane transportGO:0098662500.033
programmed cell deathGO:00125011190.033
cellular component movementGO:00069283350.032
organonitrogen compound biosynthetic processGO:1901566470.031
cortical cytoskeleton organizationGO:003086510.031
purine nucleotide metabolic processGO:0006163270.030
carboxylic acid catabolic processGO:004639530.030
cellular response to chemical stimulusGO:00708871570.029
negative regulation of biological processGO:00485193040.029
regulation of developmental processGO:00507932470.029
dicarboxylic acid metabolic processGO:004364810.028
cell motilityGO:00488702440.027
brain developmentGO:00074202930.027
mitochondrial transportGO:000683920.027
organic substance catabolic processGO:1901575280.027
oogenesisGO:0048477140.027
regulation of protein localization to nucleusGO:190018020.026
generation of neuronsGO:00486993850.026
regulation of protein complex assemblyGO:004325430.026
cell deathGO:00082191210.026
regulation of cellular ketone metabolic processGO:001056570.026
anion transportGO:0006820380.025
negative regulation of epithelial cell proliferationGO:005068010.025
single organism nuclear importGO:190259330.025
localization of cellGO:00516742440.025
regulation of primary metabolic processGO:00800903110.025
growthGO:00400071740.025
muscle cell developmentGO:00550011150.024
phosphorylationGO:0016310690.024
cellular component disassemblyGO:002241110.024
regulation of establishment of protein localizationGO:007020140.024
developmental process involved in reproductionGO:0003006270.024
gastrulationGO:00073692080.024
nuclear transportGO:005116940.024
protein complex subunit organizationGO:0071822460.023
single organism organelle organizationGO:19025891990.023
muscle structure developmentGO:00610611960.023
negative regulation of catabolic processGO:000989530.023
metal ion transportGO:0030001580.023
regulation of dna replicationGO:000627530.022
eye developmentGO:00016542770.022
lipid storageGO:001991510.022
small molecule catabolic processGO:004428230.022
digestive tract morphogenesisGO:00485462310.022
regulation of cellular biosynthetic processGO:00313262450.021
regulation of signal transductionGO:00099662250.021
regulation of intracellular protein transportGO:003315730.021
sensory organ developmentGO:00074233930.020
nucleic acid metabolic processGO:00903042440.020
regulation of cellular amino acid metabolic processGO:000652100.020
generation of precursor metabolites and energyGO:000609150.020
Human
branched chain amino acid metabolic processGO:000908110.020
cytoskeleton organizationGO:0007010960.020
cellular macromolecule metabolic processGO:00442603910.020
cognitionGO:005089010.020
camera type eye developmentGO:00430102220.020
mitochondrial electron transport nadh to ubiquinoneGO:000612010.019
cellular protein catabolic processGO:004425740.019
protein import into nucleusGO:000660630.019
regulation of cell shapeGO:000836010.019
nucleocytoplasmic transportGO:000691340.019
nucleobase containing compound biosynthetic processGO:00346542050.019
negative regulation of cellular catabolic processGO:003133030.019
macromolecular complex disassemblyGO:003298410.019
regulation of cytoplasmic transportGO:190364940.019
negative regulation of kinase activityGO:003367340.018
regulation of multicellular organismal processGO:00512392770.018
regulation of cellular amine metabolic processGO:003323800.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
neuron differentiationGO:00301823530.018
proteasomal protein catabolic processGO:001049820.018
protein metabolic processGO:00195381830.017
sequestering of calcium ionGO:005120830.017
response to organic substanceGO:00100331530.017
protein localization to nucleusGO:003450430.017
establishment of protein localization to organelleGO:007259440.017
intracellular transportGO:0046907320.017
single organism biosynthetic processGO:0044711710.017
Human Yeast
phagocytosis engulfmentGO:000691110.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
gland developmentGO:00487321430.017
cellular ketone metabolic processGO:0042180110.017
regulation of epithelial cell proliferationGO:005067830.017
cellular carbohydrate metabolic processGO:004426240.017
mitochondrion morphogenesisGO:007058420.016
nucleoside monophosphate metabolic processGO:000912360.016
homeostatic processGO:00425921420.016
regulation of signalingGO:00230512350.016
reproductionGO:0000003400.016
cell growthGO:0016049570.016
regulation of cell deathGO:00109411030.016
regulation of cell communicationGO:00106462320.016
cellular macromolecular complex assemblyGO:0034622240.016
reactive oxygen species metabolic processGO:007259360.016
ribose phosphate biosynthetic processGO:0046390200.016
response to woundingGO:00096111160.016
regulation of biosynthetic processGO:00098892500.015
deathGO:00162651210.015
negative regulation of metabolic processGO:0009892860.015
regulation of bindingGO:005109830.015
energy derivation by oxidation of organic compoundsGO:001598050.015
Human
neurotransmitter transportGO:000683620.015
protein targeting to nucleusGO:004474430.015
purine ribonucleoside monophosphate metabolic processGO:000916750.014
response to abiotic stimulusGO:00096281220.014
nuclear importGO:005117030.014
aromatic compound biosynthetic processGO:00194382170.014
positive regulation of biological processGO:00485182530.014
regulation of autophagyGO:001050630.014
protein complex biogenesisGO:0070271300.014
regulation of macromolecule metabolic processGO:00602553170.014
carbohydrate biosynthetic processGO:001605110.014
nuclear exportGO:005116810.014
hemopoiesisGO:00300971830.014
regulation of molecular functionGO:0065009700.014
proteolysis involved in cellular protein catabolic processGO:005160330.014
renal system developmentGO:0072001940.014
rna biosynthetic processGO:00327741810.014
macromolecular complex assemblyGO:0065003350.014
regulation of rna metabolic processGO:00512522240.013
head developmentGO:00603223030.013
regulation of protein transportGO:005122330.013
sensory organ morphogenesisGO:00905962000.013
inorganic ion transmembrane transportGO:0098660570.013
regulation of nucleoside metabolic processGO:000911820.013
protein importGO:001703830.013
actin cytoskeleton organizationGO:0030036630.013
ribonucleoside monophosphate metabolic processGO:000916150.013
regulation of programmed cell deathGO:00430671010.013
developmental growthGO:00485891660.013
modification dependent macromolecule catabolic processGO:004363230.013
oxidation reduction processGO:0055114410.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
neuroblast proliferationGO:000740520.012
positive regulation of transportGO:005105020.012
regulation of neural precursor cell proliferationGO:200017730.012
positive regulation of multicellular organismal processGO:0051240520.012
protein complex assemblyGO:0006461300.012
cell morphogenesisGO:00009022890.012
proteolysisGO:0006508380.012
cellular macromolecule biosynthetic processGO:00346452240.012
protein complex disassemblyGO:004324110.012
striated muscle cell developmentGO:00550021080.012
positive regulation of cellular component biogenesisGO:004408930.012
regulation of protein depolymerizationGO:190187910.012
negative regulation of response to stimulusGO:00485851040.012
neuron projection developmentGO:00311751800.011
nucleoside biosynthetic processGO:000916320.011
intracellular signal transductionGO:0035556850.011
adult behaviorGO:003053420.011
protein depolymerizationGO:005126110.011
establishment of localization in cellGO:0051649770.011
single organism intracellular transportGO:1902582250.011
positive regulation of metabolic processGO:00098931080.011
rna localizationGO:000640340.011
myofibril assemblyGO:0030239480.011
purine nucleoside triphosphate biosynthetic processGO:000914520.011
neuromuscular synaptic transmissionGO:000727420.011
tissue remodelingGO:004877140.011
regulation of nucleocytoplasmic transportGO:004682220.011
ribonucleoside metabolic processGO:0009119110.011
cellular transition metal ion homeostasisGO:004691630.011
neuron projection guidanceGO:0097485860.011
regulation of gene expressionGO:00104682650.011
anion transmembrane transportGO:0098656120.011
actin polymerization or depolymerizationGO:000815420.011
protein polymerizationGO:005125840.011
retina layer formationGO:0010842240.011
cellular localizationGO:0051641970.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
cellular response to oxygen levelsGO:007145310.011
atp metabolic processGO:004603450.011
multi organism reproductive processGO:0044703360.011
response to external biotic stimulusGO:0043207970.011
nucleotide biosynthetic processGO:0009165210.011
regulation of cytokine productionGO:000181730.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
negative regulation of protein kinase activityGO:000646940.011
negative regulation of cellular processGO:00485232830.011
primary neural tube formationGO:001402010.010
cellular homeostasisGO:0019725260.010
neurotransmitter secretionGO:000726920.010
coenzyme biosynthetic processGO:000910820.010
Human Yeast
regulation of leukocyte mediated immunityGO:000270310.010
regulation of blood vessel sizeGO:005088020.010
regulation of protein complex disassemblyGO:004324410.010
glycosyl compound metabolic processGO:1901657110.010
transcription dna templatedGO:00063511810.010
morphogenesis of an epitheliumGO:00020093330.010
heart developmentGO:00075073130.010
nitric oxide metabolic processGO:004620920.010
cell migrationGO:00164772370.010
cell projection organizationGO:00300302840.010
neural retina developmentGO:0003407490.010
positive regulation of cell adhesionGO:004578510.010
regulation of dendrite morphogenesisGO:004881430.010
negative regulation of cell communicationGO:0010648960.010

pdhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.065
disease of anatomical entityDOID:700.030
disease of cellular proliferationDOID:1456600.018
inherited metabolic disorderDOID:65500.018
organ system cancerDOID:005068600.017
cancerDOID:16200.017
endocrine gland cancerDOID:17000.017