Danio rerio

46 known processes

jhdm1db

jumonji C domain containing histone demethylase 1 homolog Db (S. cerevisiae)

(Aliases: DrKDM7b,im:7141664)

jhdm1db biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.141
cognitionGO:005089010.076
stem cell maintenanceGO:001982740.072
nucleobase containing compound metabolic processGO:00061392740.071
nucleobase containing compound biosynthetic processGO:00346542050.069
biosynthetic processGO:00090582940.067
negative regulation of cellular processGO:00485232830.063
agingGO:000756820.062
regulation of establishment of protein localizationGO:007020140.059
cellular nitrogen compound biosynthetic processGO:00442712180.059
regulation of biosynthetic processGO:00098892500.057
cellular biosynthetic processGO:00442492860.057
cellular nitrogen compound metabolic processGO:00346412900.056
generation of neuronsGO:00486993850.055
macromolecule biosynthetic processGO:00090592270.055
cellular macromolecule metabolic processGO:00442603910.053
nitrogen compound metabolic processGO:00068073190.052
brain developmentGO:00074202930.051
regulation of metabolic processGO:00192223590.050
regulation of macromolecule biosynthetic processGO:00105562250.049
rna biosynthetic processGO:00327741810.048
neuron differentiationGO:00301823530.046
regulation of macromolecule metabolic processGO:00602553170.045
central nervous system developmentGO:00074173870.045
regulation of protein transportGO:005122330.044
regulation of nitrogen compound metabolic processGO:00511712510.044
regulation of nucleobase containing compound metabolic processGO:00192192500.044
transcription dna templatedGO:00063511810.043
regulation of rna metabolic processGO:00512522240.043
positive regulation of transportGO:005105020.042
heterocycle metabolic processGO:00464832900.042
regulation of cytokine productionGO:000181730.042
morphogenesis of an epitheliumGO:00020093330.042
digestive tract morphogenesisGO:00485462310.041
digestive system developmentGO:00551232890.041
immune system processGO:00023762410.040
phagocytosisGO:000690930.040
regulation of cellular biosynthetic processGO:00313262450.040
positive regulation of cellular catabolic processGO:003133130.039
regulation of cellular macromolecule biosynthetic processGO:20001122220.039
digestive tract developmentGO:00485652650.039
regulation of transcription dna templatedGO:00063552130.039
organic substance biosynthetic processGO:19015762890.038
nucleic acid templated transcriptionGO:00976591810.038
cellular component morphogenesisGO:00329893360.038
rna metabolic processGO:00160702190.038
cellular aromatic compound metabolic processGO:00067252950.036
multicellular organism growthGO:003526440.036
sensory organ developmentGO:00074233930.036
organic cyclic compound metabolic processGO:19013603010.035
regulation of gene expressionGO:00104682650.035
autophagyGO:000691440.034
cellular macromolecule biosynthetic processGO:00346452240.034
protein dephosphorylationGO:000647030.034
nucleocytoplasmic transportGO:000691340.034
protein secretionGO:000930610.034
establishment of protein localization to organelleGO:007259440.033
cellular protein catabolic processGO:004425740.033
cellular response to chemical stimulusGO:00708871570.033
growthGO:00400071740.033
amine metabolic processGO:000930820.032
aromatic compound biosynthetic processGO:00194382170.032
cell projection morphogenesisGO:00488582440.032
nuclear transportGO:005116940.032
regulation of cellular metabolic processGO:00313233200.031
regulation of protein catabolic processGO:004217610.031
positive regulation of map kinase activityGO:004340630.031
heterocycle biosynthetic processGO:00181302150.031
maintenance of locationGO:005123540.031
response to chemicalGO:00422213200.031
protein targeting to nucleusGO:004474430.030
regulation of multicellular organism growthGO:004001440.030
positive regulation of cytokine productionGO:000181920.030
signal transductionGO:00071654550.030
regulation of rna biosynthetic processGO:20011412130.030
cellular amine metabolic processGO:004410620.029
regulation of protein complex assemblyGO:004325430.029
tube morphogenesisGO:00352393490.029
organic cyclic compound biosynthetic processGO:19013622230.029
nucleic acid metabolic processGO:00903042440.029
response to stressGO:00069502630.028
regulation of cell shapeGO:000836010.028
gene expressionGO:00104672520.028
gastrulationGO:00073692080.028
response to alkaloidGO:004327920.028
positive regulation of catabolic processGO:000989640.028
regulation of nucleic acid templated transcriptionGO:19035062130.028
neuron developmentGO:00486662620.028
oxoacid metabolic processGO:0043436310.028
cellular response to molecule of bacterial originGO:007121930.028
proteolysis involved in cellular protein catabolic processGO:005160330.028
single organism localizationGO:19025782250.027
single organism metabolic processGO:00447102170.027
hormone transportGO:000991420.027
organic acid metabolic processGO:0006082310.027
cellular response to external stimulusGO:007149620.027
peptidyl serine phosphorylationGO:001810510.027
regulation of cellular amino acid metabolic processGO:000652100.026
regulation of protein targetingGO:190353320.026
regulation of response to stimulusGO:00485832690.026
cell projection organizationGO:00300302840.026
regulation of bindingGO:005109830.026
positive regulation of cellular component biogenesisGO:004408930.026
locomotionGO:00400113130.026
regulation of developmental processGO:00507932470.026
embryonic organ morphogenesisGO:00485622740.026
Zebrafish
protein localization to plasma membraneGO:007265910.026
cell motilityGO:00488702440.026
regulation of cellular amine metabolic processGO:003323800.025
nuclear importGO:005117030.025
negative regulation of biological processGO:00485193040.025
regulation of primary metabolic processGO:00800903110.025
response to monosaccharideGO:003428430.025
cellular component movementGO:00069283350.025
cellular response to lipopolysaccharideGO:007122230.025
embryonic organ developmentGO:00485683810.025
Zebrafish
extrinsic apoptotic signaling pathwayGO:009719130.025
protein importGO:001703830.024
response to uvGO:000941130.024
positive regulation of cellular processGO:00485222010.024
single organism nuclear importGO:190259330.024
system processGO:00030081850.024
hormone secretionGO:004687920.024
regulation of intracellular protein transportGO:003315730.024
ubiquitin dependent protein catabolic processGO:000651130.024
positive regulation of biological processGO:00485182530.024
ameboidal type cell migrationGO:00016671430.024
protein localization to nucleusGO:003450430.023
cellular response to nutrient levelsGO:003166920.023
response to drugGO:004249330.023
peptide transportGO:001583310.023
cellular response to extracellular stimulusGO:003166820.023
response to topologically incorrect proteinGO:003596620.023
cell part morphogenesisGO:00329902460.023
small molecule metabolic processGO:0044281770.023
regulation of cell activationGO:005086510.023
regulation of cell communicationGO:00106462320.023
regulation of protein import into nucleusGO:004230620.023
positive regulation of secretionGO:005104710.023
cell morphogenesis involved in differentiationGO:00009041950.022
positive regulation of cell adhesionGO:004578510.022
protein polymerizationGO:005125840.022
germ line stem cell maintenanceGO:003071820.022
meiotic nuclear divisionGO:000712640.022
regulation of nucleocytoplasmic transportGO:004682220.022
negative regulation of protein phosphorylationGO:000193340.022
regulation of multicellular organismal processGO:00512392770.022
cell surface receptor signaling pathwayGO:00071663250.022
establishment of localizationGO:00512342440.022
head developmentGO:00603223030.022
gland developmentGO:00487321430.022
cellular amino acid metabolic processGO:000652070.021
regulation of apoptotic processGO:0042981980.021
Zebrafish
positive regulation of secretion by cellGO:190353210.021
positive regulation of cell cycleGO:004578730.021
liver developmentGO:0001889960.021
cell cycle g1 s phase transitionGO:004484310.021
carboxylic acid metabolic processGO:0019752220.021
post embryonic organ developmentGO:004856940.021
ribonucleoside monophosphate catabolic processGO:000915840.021
negative regulation of catabolic processGO:000989530.021
cell migrationGO:00164772370.021
specification of symmetryGO:00097992040.020
ear developmentGO:00435831270.020
cellular response to starvationGO:000926710.020
modification dependent protein catabolic processGO:001994130.020
transportGO:00068102200.020
regulation of signalingGO:00230512350.020
apoptotic processGO:00069151160.020
Zebrafish
protein acetylationGO:000647320.020
cell substrate adhesionGO:003158940.020
regulation of autophagyGO:001050630.020
urogenital system developmentGO:0001655970.020
cell matrix adhesionGO:000716040.020
proteasomal protein catabolic processGO:001049820.020
startle responseGO:000196440.020
positive regulation of cytoskeleton organizationGO:005149530.020
phagocytosis engulfmentGO:000691110.020
positive regulation of nitrogen compound metabolic processGO:0051173690.020
positive regulation of cell activationGO:005086710.020
cellular response to biotic stimulusGO:007121630.019
regulation of hormone secretionGO:004688320.019
positive regulation of apoptotic signaling pathwayGO:200123510.019
regulation of signal transductionGO:00099662250.019
peptidyl serine modificationGO:001820920.019
regulation of cytoplasmic transportGO:190364940.019
protein import into nucleusGO:000660630.019
deathGO:00162651210.019
Zebrafish
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
regulation of multicellular organismal developmentGO:20000262230.019
cellular protein metabolic processGO:00442671290.019
inner ear developmentGO:00488391260.019
mitochondrion organizationGO:000700540.018
cell deathGO:00082191210.018
Zebrafish
positive regulation of macromolecule metabolic processGO:0010604930.018
developmental growthGO:00485891660.018
cell morphogenesisGO:00009022890.018
single organism transportGO:00447652060.018
regulation of neurogenesisGO:0050767870.018
fin developmentGO:0033333770.018
multi organism cellular processGO:004476420.018
heart developmentGO:00075073130.018
axon developmentGO:00615641660.018
gtp catabolic processGO:000618420.018
organelle organizationGO:00069962270.018
cell morphogenesis involved in neuron differentiationGO:00486671630.018
regulation of cellular protein catabolic processGO:190336210.018
lipid storageGO:001991510.017
response to external stimulusGO:00096052640.017
adult behaviorGO:003053420.017
regulation of biological qualityGO:00650082630.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
cellular response to light stimulusGO:007148240.017
cellular response to radiationGO:007147840.017
regulation of cellular ketone metabolic processGO:001056570.017
regulation of programmed cell deathGO:00430671010.017
Zebrafish
neuron projection morphogenesisGO:00488121610.017
regulation of protein ubiquitinationGO:003139630.017
regulation of synaptic plasticityGO:004816710.017
membrane invaginationGO:001032410.017
negative regulation of protein kinase activityGO:000646940.017
negative regulation of developmental processGO:0051093650.016
organonitrogen compound metabolic processGO:1901564740.016
response to abiotic stimulusGO:00096281220.016
transcription from rna polymerase ii promoterGO:0006366800.016
interspecies interaction between organismsGO:004441940.016
localization of cellGO:00516742440.016
negative regulation of cellular catabolic processGO:003133030.016
modification dependent macromolecule catabolic processGO:004363230.016
regulation of cell differentiationGO:00455951420.016
response to hexoseGO:000974630.016
locomotor rhythmGO:004547530.016
g1 s transition of mitotic cell cycleGO:000008210.016
negative regulation of protein transportGO:005122430.016
stem cell differentiationGO:00488631170.016
regionalizationGO:00030022740.016
cellular ketone metabolic processGO:0042180110.016
regulation of protein bindingGO:004339330.016
regulation of protein localization to nucleusGO:190018020.016
viral processGO:001603210.016
neuron neuron synaptic transmissionGO:000727010.016
regulation of anatomical structure morphogenesisGO:00226031300.016
rna localizationGO:000640340.015
cellular component assemblyGO:00226071700.015
mitotic dna damage checkpointGO:004477340.015
positive regulation of cellular metabolic processGO:0031325940.015
programmed cell deathGO:00125011190.015
Zebrafish
symbiosis encompassing mutualism through parasitismGO:004440340.015
response to ketoneGO:190165410.015
atp catabolic processGO:000620040.015
vasculature developmentGO:00019442780.015
positive regulation of protein complex assemblyGO:003133420.015
negative regulation of apoptotic processGO:0043066550.015
taxisGO:00423301090.015
neurological system processGO:0050877620.015
single organism organelle organizationGO:19025891990.015
positive regulation of wound healingGO:009030310.015
internal protein amino acid acetylationGO:000647520.015
regulation of cell substrate adhesionGO:001081010.015
centrosome organizationGO:005129710.015
negative regulation of cytokine productionGO:000181810.015
regulation of metal ion transportGO:001095940.015
skeletal system developmentGO:00015011810.015
Zebrafish
response to organic substanceGO:00100331530.015
exocytosisGO:000688710.015
response to woundingGO:00096111160.015
muscle structure developmentGO:00610611960.015
response to carbohydrateGO:000974330.015
regulation of inflammatory responseGO:005072720.015
embryonic skeletal system morphogenesisGO:0048704930.015
Zebrafish
response to glucoseGO:000974930.015
pectoral fin developmentGO:0033339500.014
hepaticobiliary system developmentGO:0061008980.014
cellular response to topologically incorrect proteinGO:003596720.014
negative regulation of mapk cascadeGO:004340940.014
negative regulation of cytoplasmic transportGO:190365020.014
phosphate containing compound metabolic processGO:00067961080.014
membrane fusionGO:006102520.014
determination of left right symmetryGO:00073681790.014
guanosine containing compound metabolic processGO:190106840.014
regulation of stem cell proliferationGO:007209120.014
microtubule organizing center organizationGO:003102310.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
glucose homeostasisGO:004259310.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
regulation of nucleotide catabolic processGO:003081120.014
cellular component biogenesisGO:00440851780.014
positive regulation of cellular amine metabolic processGO:003324000.014
positive regulation of immune effector processGO:000269930.014
actin filament based movementGO:003004810.014
tissue remodelingGO:004877140.014
mesenchyme developmentGO:00604851270.014
regulation of dendrite developmentGO:005077330.014
antimicrobial humoral responseGO:001973020.014
organic substance transportGO:0071702580.014
regulation of production of molecular mediator of immune responseGO:000270010.014
golgi vesicle transportGO:004819330.014
production of molecular mediator of immune responseGO:000244020.014
mononuclear cell proliferationGO:003294310.014
developmental growth involved in morphogenesisGO:0060560860.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
negative regulation of cell deathGO:0060548600.014
establishment of protein localization to plasma membraneGO:009000210.014
regulation of protein polymerizationGO:003227120.013
homeostatic processGO:00425921420.013
regulation of localizationGO:00328791040.013
regulation of cell deathGO:00109411030.013
Zebrafish
leukocyte proliferationGO:007066110.013
lymphocyte proliferationGO:004665110.013
erk1 and erk2 cascadeGO:007037140.013
cellular component disassemblyGO:002241110.013
negative regulation of metabolic processGO:0009892860.013
compound eye developmentGO:004874920.013
peptidyl lysine acetylationGO:001839420.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
negative regulation of intracellular protein transportGO:009031730.013
somatic muscle developmentGO:000752540.013
heart processGO:0003015710.013
nucleoside monophosphate catabolic processGO:000912540.013
stem cell proliferationGO:007208940.013
gtp metabolic processGO:004603940.013
positive regulation of cellular biosynthetic processGO:0031328680.013
negative regulation of kinase activityGO:003367340.013
regulation of nucleoside metabolic processGO:000911820.013
embryo development ending in birth or egg hatchingGO:00097922710.013
Zebrafish
guanosine containing compound catabolic processGO:190106920.013
regulation of erk1 and erk2 cascadeGO:007037240.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
axonogenesisGO:00074091520.013
regulation of purine nucleotide catabolic processGO:003312120.013
negative regulation of macromolecule metabolic processGO:0010605760.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
adherens junction organizationGO:003433240.013
meiotic cell cycle processGO:190304630.013
phosphorus metabolic processGO:00067931090.013
renal system developmentGO:0072001940.013
response to amino acidGO:004320020.013
mitotic dna integrity checkpointGO:004477440.013
negative regulation of intracellular transportGO:003238730.013
heart contractionGO:0060047710.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
positive regulation of dna metabolic processGO:005105410.012
alternative mrna splicing via spliceosomeGO:000038010.012
positive regulation of rna biosynthetic processGO:1902680570.012
kidney developmentGO:0001822920.012
response to radiationGO:0009314510.012
determination of bilateral symmetryGO:00098552040.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
appendage morphogenesisGO:0035107560.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
intracellular signal transductionGO:0035556850.012
neuron projection developmentGO:00311751800.012
pigment granule transportGO:0051904190.012
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.012
actin polymerization or depolymerizationGO:000815420.012
regulation of circadian rhythmGO:004275240.012
pancreas developmentGO:0031016840.012
embryonic skeletal system developmentGO:0048706970.012
Zebrafish
organism emergence from protective structureGO:007168440.012
mesenchymal cell developmentGO:0014031780.012
macromolecule modificationGO:00434121110.012
stem cell developmentGO:0048864820.012
regulation of rho protein signal transductionGO:003502320.012
negative regulation of programmed cell deathGO:0043069580.012
epithelial tube morphogenesisGO:00605621480.012
internal peptidyl lysine acetylationGO:001839320.012
action potentialGO:0001508190.012
cellular amide metabolic processGO:004360340.012
eye developmentGO:00016542770.012
neuron projection extensionGO:1990138450.012
blood vessel morphogenesisGO:00485142160.012
negative regulation of cell differentiationGO:0045596460.012
negative regulation of cellular biosynthetic processGO:0031327550.012
multicellular organismal signalingGO:0035637220.012
response to unfolded proteinGO:000698620.012
regulation of nervous system developmentGO:0051960900.012
nuclear exportGO:005116810.012
protein acylationGO:004354330.012
response to organic cyclic compoundGO:0014070510.011
development of primary female sexual characteristicsGO:004654540.011
heart morphogenesisGO:00030071560.011
regulation of transporter activityGO:003240920.011
muscle tissue developmentGO:00605371100.011
synaptic vesicle localizationGO:009747910.011
chemosensory behaviorGO:000763510.011
carbohydrate homeostasisGO:003350010.011
negative regulation of map kinase activityGO:004340720.011
negative regulation of biosynthetic processGO:0009890550.011
regulation of cell matrix adhesionGO:000195210.011
cartilage developmentGO:0051216960.011
melanin metabolic processGO:000658220.011
regulation of synapse organizationGO:005080730.011
positive regulation of stress activated mapk cascadeGO:003287430.011
embryonic limb morphogenesisGO:003032620.011
regulation of wound healingGO:006104120.011
protein metabolic processGO:00195381830.011
regulation of carbohydrate metabolic processGO:000610940.011
positive regulation of stem cell proliferationGO:200064810.011
regulation of membrane potentialGO:0042391230.011
response to external biotic stimulusGO:0043207970.011
positive regulation of nucleotide catabolic processGO:003081310.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
regulation of cell developmentGO:00602841000.011
positive regulation of response to stimulusGO:0048584800.011
positive regulation of nucleoside metabolic processGO:004597910.011
stem cell divisionGO:001714510.011
regenerationGO:0031099910.011
negative regulation of cellular metabolic processGO:0031324770.011
chordate embryonic developmentGO:00430092710.011
Zebrafish
regulation of transmembrane transporter activityGO:002289820.011
protein stabilizationGO:005082120.011
er nucleus signaling pathwayGO:000698420.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
regulation of ion transmembrane transporter activityGO:003241220.011
positive regulation of blood circulationGO:190352420.011
positive regulation of metabolic processGO:00098931080.011
synaptic growth at neuromuscular junctionGO:005112420.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
regulation of reactive oxygen species metabolic processGO:200037720.011
regulation of reproductive processGO:200024140.011
negative regulation of protein import into nucleusGO:004230820.010
double strand break repairGO:000630230.010
transmembrane transportGO:00550851200.010
mitotic cell cycleGO:0000278640.010
response to glucocorticoidGO:005138410.010
sensory organ morphogenesisGO:00905962000.010
regulation of calcium ion transportGO:005192420.010
multicellular organismal response to stressGO:003355520.010
negative regulation of response to stimulusGO:00485851040.010
macroautophagyGO:001623610.010
establishment of synaptic vesicle localizationGO:009748010.010
regulation of muscle contractionGO:000693730.010
negative regulation of multi organism processGO:004390130.010
regulation of meiotic cell cycleGO:005144510.010
regulation of gtp catabolic processGO:003312420.010
cellular protein modification processGO:00064641000.010
organelle fusionGO:004828430.010
positive regulation of multi organism processGO:004390230.010
cell cycle g2 m phase transitionGO:004483940.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
neuroblast proliferationGO:000740520.010
response to other organismGO:0051707970.010
chemotaxisGO:00069351040.010
positive regulation of gene expressionGO:0010628710.010
blood vessel developmentGO:00015682460.010

jhdm1db disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.020
organ system cancerDOID:005068600.018
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
disease of metabolismDOID:001466700.012
musculoskeletal system diseaseDOID:1700.010