Danio rerio

64 known processes

hif1al

hypoxia-inducible factor 1, alpha subunit, like

(Aliases: MGC63965,zgc:63965)

hif1al biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
biosynthetic processGO:00090582940.412
locomotionGO:00400113130.256
Fly
signal transductionGO:00071654550.236
morphogenesis of an epitheliumGO:00020093330.228
hormone transportGO:000991420.189
head developmentGO:00603223030.176
endocrine hormone secretionGO:006098620.169
cellular aromatic compound metabolic processGO:00067252950.163
single organism localizationGO:19025782250.159
larval developmentGO:000216420.145
response to external stimulusGO:00096052640.141
macromolecule biosynthetic processGO:00090592270.138
cellular nitrogen compound biosynthetic processGO:00442712180.138
growthGO:00400071740.135
Fly
regulation of metabolic processGO:00192223590.130
brain developmentGO:00074202930.129
transportGO:00068102200.129
regulation of biosynthetic processGO:00098892500.121
organic cyclic compound biosynthetic processGO:19013622230.120
regulation of cellular macromolecule biosynthetic processGO:20001122220.116
axon developmentGO:00615641660.115
agingGO:000756820.113
oxoacid metabolic processGO:0043436310.108
regulation of transcription dna templatedGO:00063552130.106
nucleobase containing compound metabolic processGO:00061392740.104
response to glucoseGO:000974930.095
aromatic compound biosynthetic processGO:00194382170.094
regulation of cell shapeGO:000836010.094
regulation of nucleic acid templated transcriptionGO:19035062130.094
sensory organ morphogenesisGO:00905962000.090
cell projection organizationGO:00300302840.088
cellular biosynthetic processGO:00442492860.088
cellular nitrogen compound metabolic processGO:00346412900.087
positive regulation of transportGO:005105020.085
cell morphogenesis involved in differentiationGO:00009041950.084
response to monosaccharideGO:003428430.083
regulation of signal transductionGO:00099662250.083
embryonic organ morphogenesisGO:00485622740.082
response to carbohydrateGO:000974330.081
cellular macromolecule metabolic processGO:00442603910.081
regionalizationGO:00030022740.080
heterocycle biosynthetic processGO:00181302150.080
rna metabolic processGO:00160702190.078
tube morphogenesisGO:00352393490.077
system processGO:00030081850.077
neuron projection morphogenesisGO:00488121610.074
organic substance biosynthetic processGO:19015762890.073
transcription from rna polymerase ii promoterGO:0006366800.072
Human Rat Fly
regulation of macromolecule metabolic processGO:00602553170.072
response to abiotic stimulusGO:00096281220.071
negative regulation of secretionGO:005104820.070
positive regulation of cellular component biogenesisGO:004408930.070
cell morphogenesis involved in neuron differentiationGO:00486671630.070
regulation of rna metabolic processGO:00512522240.068
response to chemicalGO:00422213200.068
Fly
regulation of circadian rhythmGO:004275240.068
regulation of nitrogen compound metabolic processGO:00511712510.068
regulation of nucleobase containing compound metabolic processGO:00192192500.067
convergent extensionGO:00600261180.066
endocrine processGO:005088620.066
generation of neuronsGO:00486993850.066
axonogenesisGO:00074091520.065
epithelial cell morphogenesisGO:000338220.064
regulation of cellular metabolic processGO:00313233200.064
regulation of protein complex assemblyGO:004325430.062
phagocytosisGO:000690930.062
cell morphogenesisGO:00009022890.061
positive regulation of signalingGO:0023056560.060
positive regulation of protein complex assemblyGO:003133420.060
regulation of cellular biosynthetic processGO:00313262450.060
nucleic acid metabolic processGO:00903042440.059
response to light stimulusGO:0009416460.058
ameboidal type cell migrationGO:00016671430.057
small molecule metabolic processGO:0044281770.057
enzyme linked receptor protein signaling pathwayGO:00071671060.055
response to hexoseGO:000974630.053
nucleobase containing compound biosynthetic processGO:00346542050.053
gene expressionGO:00104672520.052
regulation of dendrite developmentGO:005077330.051
sensory organ developmentGO:00074233930.050
anion transportGO:0006820380.050
autophagyGO:000691440.049
Fly
stem cell maintenanceGO:001982740.049
single organism transportGO:00447652060.048
odontogenesis of dentin containing toothGO:004247510.046
cognitionGO:005089010.045
synaptic growth at neuromuscular junctionGO:005112420.045
digestive system developmentGO:00551232890.045
hormone secretionGO:004687920.044
regulation of macromolecule biosynthetic processGO:00105562250.044
steroid hormone secretionGO:003592910.044
rna biosynthetic processGO:00327741810.044
adult behaviorGO:003053420.044
regulation of hormone secretionGO:004688320.043
nitrogen compound metabolic processGO:00068073190.043
establishment of localizationGO:00512342440.043
cellular amino acid metabolic processGO:000652070.042
embryonic organ developmentGO:00485683810.042
skeletal system developmentGO:00015011810.042
maintenance of locationGO:005123540.042
organic cyclic compound metabolic processGO:19013603010.041
neuron neuron synaptic transmissionGO:000727010.041
neuron differentiationGO:00301823530.041
regulation of protein polymerizationGO:003227120.041
organic acid metabolic processGO:0006082310.041
positive regulation of catabolic processGO:000989640.041
Fly
digestive tract developmentGO:00485652650.041
transcription dna templatedGO:00063511810.040
regulation of multicellular organism growthGO:004001440.040
cellular macromolecule biosynthetic processGO:00346452240.040
neuron developmentGO:00486662620.040
wound healingGO:0042060900.040
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.039
deathGO:00162651210.039
cell surface receptor signaling pathwayGO:00071663250.038
regulation of protein catabolic processGO:004217610.037
epithelial cell differentiationGO:00308551160.037
hemopoiesisGO:00300971830.037
positive regulation of cell communicationGO:0010647560.037
epidermal cell differentiationGO:0009913360.037
multi organism processGO:00517041340.037
Fly
negative regulation of kinase activityGO:003367340.037
neuron projection developmentGO:00311751800.037
multicellular organism growthGO:003526440.036
regulation of primary metabolic processGO:00800903110.036
phosphorus metabolic processGO:00067931090.036
regulation of cell communicationGO:00106462320.036
alpha amino acid metabolic processGO:190160530.036
sensory system developmentGO:0048880760.036
peptide transportGO:001583310.035
protein modification processGO:00362111000.035
actin filament based movementGO:003004810.035
dicarboxylic acid transportGO:000683510.034
organelle organizationGO:00069962270.034
regulation of growth rateGO:004000910.034
regulation of signalingGO:00230512350.034
response to corticosteroidGO:003196010.033
retina development in camera type eyeGO:00600411460.033
neuron projection guidanceGO:0097485860.033
cellular protein modification processGO:00064641000.033
positive regulation of protein polymerizationGO:003227320.033
fin morphogenesisGO:0033334530.033
positive regulation of biological processGO:00485182530.032
Rat Fly
nucleic acid templated transcriptionGO:00976591810.032
regulation of rna biosynthetic processGO:20011412130.032
hindbrain developmentGO:0030902910.032
cell migrationGO:00164772370.032
Fly
carbohydrate biosynthetic processGO:001605110.031
single organism metabolic processGO:00447102170.031
central nervous system neuron differentiationGO:0021953740.031
actin filament polymerizationGO:003004120.030
inner ear developmentGO:00488391260.030
regulation of biological qualityGO:00650082630.030
amine metabolic processGO:000930820.030
negative regulation of cellular biosynthetic processGO:0031327550.029
Human
signal transduction in absence of ligandGO:003803410.029
positive regulation of cell cycleGO:004578730.029
regulation of response to stimulusGO:00485832690.029
skin developmentGO:0043588540.029
pancreas developmentGO:0031016840.029
single organism nuclear importGO:190259330.028
regulation of transcription from rna polymerase ii promoterGO:00063571140.028
Human Rat Fly
regulation of synapse organizationGO:005080730.028
regulation of cellular amine metabolic processGO:003323800.028
sulfate transmembrane transportGO:190235820.028
cellular response to external stimulusGO:007149620.027
developmental growthGO:00485891660.027
vasculature developmentGO:00019442780.027
camera type eye morphogenesisGO:00485931080.027
camera type eye developmentGO:00430102220.027
regulation of gene expressionGO:00104682650.027
lipid storageGO:001991510.027
negative regulation of protein phosphorylationGO:000193340.026
cellular response to nutrient levelsGO:003166920.026
ear developmentGO:00435831270.026
regulation of multicellular organismal processGO:00512392770.026
negative regulation of cellular metabolic processGO:0031324770.026
Human
regulation of localizationGO:00328791040.026
Fly
response to stressGO:00069502630.026
localization of cellGO:00516742440.026
Fly
gland developmentGO:00487321430.026
cell part morphogenesisGO:00329902460.025
response to uvGO:000941130.025
negative regulation of protein kinase activityGO:000646940.025
positive regulation of cellular catabolic processGO:003133130.025
Fly
tissue remodelingGO:004877140.025
regulation of cellular carbohydrate metabolic processGO:001067540.024
regulation of bindingGO:005109830.023
response to glucocorticoidGO:005138410.023
wnt signaling pathwayGO:0016055800.023
regulation of endothelial cell proliferationGO:000193610.023
cellular component movementGO:00069283350.023
Fly
stem cell fate commitmentGO:004886510.023
negative regulation of macromolecule metabolic processGO:0010605760.023
Human
nuclear importGO:005117030.023
heterocycle metabolic processGO:00464832900.023
microtubule organizing center organizationGO:003102310.022
regulation of synaptic growth at neuromuscular junctionGO:000858210.022
cell projection morphogenesisGO:00488582440.022
cellular protein metabolic processGO:00442671290.022
macromolecule modificationGO:00434121110.022
regulation of developmental processGO:00507932470.022
regulation of metal ion transportGO:001095940.022
somatic stem cell maintenanceGO:003501910.022
protein localization to nucleusGO:003450430.022
eye developmentGO:00016542770.021
cellular component morphogenesisGO:00329893360.021
developmental growth involved in morphogenesisGO:0060560860.021
digestive tract morphogenesisGO:00485462310.021
peripheral nervous system developmentGO:0007422550.021
negative regulation of biological processGO:00485193040.021
Human Fly
immune system developmentGO:00025201910.021
cellular component disassemblyGO:002241110.021
mitotic cell cycle processGO:1903047480.021
cellular carbohydrate metabolic processGO:004426240.021
positive regulation of epithelial cell proliferationGO:005067910.021
neurotransmitter secretionGO:000726920.021
embryonic limb morphogenesisGO:003032620.021
blood vessel developmentGO:00015682460.021
eye morphogenesisGO:00485921440.021
negative regulation of nucleic acid templated transcriptionGO:1903507450.021
Human
negative regulation of rna biosynthetic processGO:1902679450.020
Human
regulation of hormone levelsGO:0010817210.020
response to nutrientGO:000758430.020
cellular response to extracellular stimulusGO:003166820.020
carbohydrate homeostasisGO:003350010.020
pectoral fin developmentGO:0033339500.020
cell deathGO:00082191210.020
regulation of protein bindingGO:004339330.020
organic substance transportGO:0071702580.020
negative regulation of cellular processGO:00485232830.020
Human Fly
regulation of stem cell proliferationGO:007209120.020
mononuclear cell proliferationGO:003294310.020
response to biotic stimulusGO:0009607970.019
cell cell signalingGO:0007267520.019
negative regulation of response to stimulusGO:00485851040.019
ear morphogenesisGO:0042471640.019
phosphorylationGO:0016310690.019
lymphocyte proliferationGO:004665110.019
cellular response to xenobiotic stimulusGO:0071466350.019
response to bacteriumGO:0009617580.019
negative regulation of macromolecule biosynthetic processGO:0010558480.019
Human
skeletal system morphogenesisGO:00487051020.019
centrosome organizationGO:005129710.019
carboxylic acid transportGO:004694280.019
protein metabolic processGO:00195381830.019
regulation of synapse assemblyGO:005196330.019
single organism organelle organizationGO:19025891990.018
stem cell proliferationGO:007208940.018
response to organic substanceGO:00100331530.018
Fly
response to lipidGO:0033993600.018
protein polymerizationGO:005125840.018
positive regulation of notch signaling pathwayGO:004574730.018
regulation of cellular ketone metabolic processGO:001056570.018
actin mediated cell contractionGO:007025210.018
positive regulation of i kappab kinase nf kappab signalingGO:004312330.018
segmentationGO:0035282970.018
glucose homeostasisGO:004259310.018
regulation of locomotionGO:0040012550.017
Fly
regulation of cell deathGO:00109411030.017
nuclear transportGO:005116940.017
embryonic cranial skeleton morphogenesisGO:0048701900.017
regulation of lipid transportGO:003236840.017
cellular response to organic cyclic compoundGO:0071407380.017
cellular response to starvationGO:000926710.017
g1 s transition of mitotic cell cycleGO:000008210.017
response to endogenous stimulusGO:0009719830.017
Fly
phosphate containing compound metabolic processGO:00067961080.017
extrinsic apoptotic signaling pathwayGO:009719130.017
membrane invaginationGO:001032410.017
regulation of apoptotic processGO:0042981980.017
regulation of neuron projection developmentGO:0010975400.017
pigmentationGO:0043473850.017
carboxylic acid metabolic processGO:0019752220.017
nerve developmentGO:0021675450.016
regulation of response to oxidative stressGO:190288220.016
immune system processGO:00023762410.016
inner ear morphogenesisGO:0042472630.016
morphogenesis of an epithelial foldGO:006057110.016
leukocyte homeostasisGO:000177620.016
cell cycle g1 s phase transitionGO:004484310.016
appendage developmentGO:0048736800.016
protein polyubiquitinationGO:000020940.016
cellular response to endogenous stimulusGO:0071495680.016
Fly
entrainment of circadian clock by photoperiodGO:004315310.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
regulation of axonogenesisGO:0050770320.016
regulation of receptor activityGO:001046920.016
embryo development ending in birth or egg hatchingGO:00097922710.016
response to hormoneGO:0009725480.016
Fly
regulation of cell morphogenesisGO:0022604420.016
regulation of cellular component movementGO:0051270550.016
Fly
positive regulation of stress activated mapk cascadeGO:003287430.016
forebrain cell migrationGO:002188510.016
fin developmentGO:0033333770.016
keratinocyte differentiationGO:003021600.015
cellular response to stressGO:0033554620.015
Fly
purine ribonucleoside monophosphate catabolic processGO:000916940.015
regulation of neuron differentiationGO:0045664560.015
heart developmentGO:00075073130.015
positive regulation of cytoskeleton organizationGO:005149530.015
regulation of nervous system developmentGO:0051960900.015
bicarbonate transportGO:001570140.015
convergent extension involved in axis elongationGO:0060028260.015
single organism membrane fusionGO:004480120.015
regulation of rho protein signal transductionGO:003502320.015
hepaticobiliary system developmentGO:0061008980.015
response to drugGO:004249330.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
Human
regulation of carbohydrate metabolic processGO:000610940.015
macromolecular complex disassemblyGO:003298410.015
protein phosphorylationGO:0006468470.015
behaviorGO:0007610740.015
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.015
purine nucleoside monophosphate catabolic processGO:000912840.014
lateral line system developmentGO:0048925760.014
regulation of steroid hormone secretionGO:200083110.014
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.014
regulation of autophagyGO:001050630.014
Fly
mitochondrion organizationGO:000700540.014
monocyte differentiationGO:003022420.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
epithelial tube morphogenesisGO:00605621480.014
establishment of protein localization to organelleGO:007259440.014
lipid homeostasisGO:005508830.014
startle responseGO:000196440.014
regulation of cell activationGO:005086510.014
negative regulation of multicellular organismal processGO:0051241690.014
negative regulation of stem cell differentiationGO:200073720.014
response to salt stressGO:0009651100.014
regulation of molecular functionGO:0065009700.014
positive regulation of multi organism processGO:004390230.014
cellular amine metabolic processGO:004410620.014
regulation of reproductive processGO:200024140.014
regulation of carbohydrate biosynthetic processGO:004325510.014
cellular component biogenesisGO:00440851780.014
regulation of transportGO:0051049450.014
pectoral fin morphogenesisGO:0035138290.014
determination of bilateral symmetryGO:00098552040.014
cellular response to organic substanceGO:00713101050.014
Fly
atp catabolic processGO:000620040.014
regenerationGO:0031099910.014
response to external biotic stimulusGO:0043207970.014
rhythmic processGO:0048511210.014
organonitrogen compound metabolic processGO:1901564740.014
compound eye developmentGO:004874920.013
neurological system processGO:0050877620.013
response to xenobiotic stimulusGO:0009410450.013
multicellular organismal metabolic processGO:004423620.013
meiotic cell cycle processGO:190304630.013
lateral line developmentGO:0048882660.013
positive regulation of secretion by cellGO:190353210.013
protein importGO:001703830.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
establishment of epithelial cell polarityGO:009016220.013
regulation of stem cell differentiationGO:200073640.013
central nervous system developmentGO:00074173870.013
embryonic heart tube developmentGO:00350501330.013
polarized epithelial cell differentiationGO:003085940.013
regulation of catalytic activityGO:0050790550.013
regulation of cellular component organizationGO:0051128860.013
Fly
cellular transition metal ion homeostasisGO:004691630.013
protein complex disassemblyGO:004324110.013
mitotic cell cycleGO:0000278640.013
positive regulation of secretionGO:005104710.012
regulation of cellular amino acid metabolic processGO:000652100.012
response to oxygen containing compoundGO:1901700550.012
Fly
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.012
specification of organ identityGO:001009220.012
ribonucleoside monophosphate catabolic processGO:000915840.012
negative regulation of metabolic processGO:0009892860.012
Human
regulation of cell morphogenesis involved in differentiationGO:0010769380.012
exocrine system developmentGO:0035272280.012
neurotransmitter transportGO:000683620.012
bmp signaling pathwayGO:0030509520.012
positive regulation of dna metabolic processGO:005105410.012
negative regulation of secretion by cellGO:190353120.012
negative regulation of programmed cell deathGO:0043069580.012
immunoglobulin productionGO:000237710.012
regulation of reactive oxygen species metabolic processGO:200037720.012
regulation of cellular protein catabolic processGO:190336210.012
regulation of wound healingGO:006104120.012
cation transportGO:0006812810.012
connective tissue developmentGO:0061448990.012
cellular response to radiationGO:007147840.012
peptidyl serine modificationGO:001820920.012
specification of symmetryGO:00097992040.012
glial cell migrationGO:000834730.012
regulation of muscle contractionGO:000693730.012
cellular response to oxygen levelsGO:007145310.012
Fly
chemotaxisGO:00069351040.012
small gtpase mediated signal transductionGO:000726480.012
positive regulation of cellular processGO:00485222010.012
Rat Fly
cellular amide metabolic processGO:004360340.011
single organism biosynthetic processGO:0044711710.011
regulation of cellular response to oxidative stressGO:190040720.011
response to alcoholGO:0097305140.011
somitogenesisGO:0001756870.011
post embryonic organ developmentGO:004856940.011
centrosome cycleGO:000709810.011
cellular localizationGO:0051641970.011
actin polymerization or depolymerizationGO:000815420.011
stem cell developmentGO:0048864820.011
negative regulation of epithelial cell migrationGO:001063310.011
stem cell differentiationGO:00488631170.011
regulation of organ growthGO:004662030.011
regulation of anatomical structure morphogenesisGO:00226031300.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
cell proliferationGO:0008283800.011
cellular component assemblyGO:00226071700.011
phagocytosis engulfmentGO:000691110.011
lipid metabolic processGO:0006629520.011
ion transportGO:00068111140.011
mechanosensory behaviorGO:000763820.011
myeloid cell differentiationGO:0030099860.011
neural crest cell developmentGO:0014032620.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.011
positive regulation of epithelial cell migrationGO:001063420.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
liver developmentGO:0001889960.011
mitotic cytokinesisGO:000028130.011
phosphatidylinositol 3 kinase signalingGO:001406520.011
protein import into nucleusGO:000660630.011
foregut morphogenesisGO:000744040.011
gastrulationGO:00073692080.011
carbohydrate derivative biosynthetic processGO:1901137430.011
nucleocytoplasmic transportGO:000691340.011
appendage morphogenesisGO:0035107560.011
retina morphogenesis in camera type eyeGO:0060042790.011
response to inorganic substanceGO:0010035380.011
positive regulation of signal transductionGO:0009967560.011
neuroblast proliferationGO:000740520.011
proepicardium developmentGO:000334240.011
anterior posterior pattern specificationGO:00099521520.010
phosphatidylinositol mediated signalingGO:004801520.010
negative regulation of multi organism processGO:004390130.010
regulation of cell migrationGO:0030334400.010
Fly
urogenital system developmentGO:0001655970.010
response to steroid hormoneGO:0048545350.010
cell fate commitmentGO:0045165990.010
embryonic skeletal system morphogenesisGO:0048704930.010
auditory receptor cell developmentGO:006011780.010
positive regulation of rna biosynthetic processGO:1902680570.010
Rat Fly
response to peptide hormoneGO:004343460.010
Fly
female sex differentiationGO:004666040.010
regulation of chondrocyte differentiationGO:003233010.010
smooth muscle tissue developmentGO:004874510.010
mitotic nuclear divisionGO:0007067180.010
gliogenesisGO:0042063450.010
entrainment of circadian clockGO:000964920.010

hif1al disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.022
tauopathyDOID:68000.022
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
neurodegenerative diseaseDOID:128900.022
disease of mental healthDOID:15000.017
disease of metabolismDOID:001466700.017
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
cardiovascular system diseaseDOID:128700.012
inherited metabolic disorderDOID:65500.012
organ system cancerDOID:005068600.011