Danio rerio

19 known processes

fgf21

fibroblast growth factor 21

fgf21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of transportGO:005105020.071
cellular component morphogenesisGO:00329893360.058
generation of neuronsGO:00486993850.050
single organism metabolic processGO:00447102170.050
camera type eye developmentGO:00430102220.048
exocytosisGO:000688710.046
regulation of establishment of protein localizationGO:007020140.046
eye developmentGO:00016542770.045
agingGO:000756820.042
regulation of protein transportGO:005122330.041
larval developmentGO:000216420.038
signal transductionGO:00071654550.038
transportGO:00068102200.036
sensory organ developmentGO:00074233930.036
microtubule based movementGO:0007018330.035
regulation of synapse organizationGO:005080730.034
cellular component movementGO:00069283350.034
blood vessel developmentGO:00015682460.034
regulation of cell communicationGO:00106462320.034
heterocycle metabolic processGO:00464832900.033
positive regulation of biological processGO:00485182530.033
positive regulation of cellular component biogenesisGO:004408930.033
regulation of cellular metabolic processGO:00313233200.031
guanosine containing compound catabolic processGO:190106920.031
single organism localizationGO:19025782250.031
establishment of localizationGO:00512342440.031
cilium organizationGO:0044782710.031
single fertilizationGO:000733830.030
fertilizationGO:000956630.030
regulation of primary metabolic processGO:00800903110.030
cilium morphogenesisGO:0060271850.030
cell part morphogenesisGO:00329902460.029
positive regulation of catabolic processGO:000989640.028
response to stressGO:00069502630.028
regulation of carbohydrate metabolic processGO:000610940.028
amine metabolic processGO:000930820.028
biosynthetic processGO:00090582940.028
guanosine containing compound metabolic processGO:190106840.027
maintenance of locationGO:005123540.027
cellular amine metabolic processGO:004410620.027
regulation of synaptic plasticityGO:004816710.027
protein polymerizationGO:005125840.027
retina development in camera type eyeGO:00600411460.027
positive regulation of cellular catabolic processGO:003133130.027
cellular carbohydrate metabolic processGO:004426240.026
positive regulation of secretion by cellGO:190353210.026
stem cell maintenanceGO:001982740.026
regulation of metabolic processGO:00192223590.026
regulation of intracellular protein transportGO:003315730.025
positive regulation of cytokine productionGO:000181920.025
regulation of protein localization to nucleusGO:190018020.025
cellular protein catabolic processGO:004425740.025
blood vessel morphogenesisGO:00485142160.025
neuron differentiationGO:00301823530.025
adult behaviorGO:003053420.024
regulation of cellular amino acid metabolic processGO:000652100.024
camera type eye morphogenesisGO:00485931080.024
positive regulation of secretionGO:005104710.024
multicellular organism growthGO:003526440.024
lipid storageGO:001991510.024
response to chemicalGO:00422213200.024
developmental growthGO:00485891660.024
modification dependent protein catabolic processGO:001994130.024
regulation of synapse assemblyGO:005196330.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.023
regulation of cellular amine metabolic processGO:003323800.023
regulation of cellular ketone metabolic processGO:001056570.023
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.023
cell migrationGO:00164772370.023
positive regulation of i kappab kinase nf kappab signalingGO:004312330.023
cell surface receptor signaling pathwayGO:00071663250.023
system processGO:00030081850.023
positive regulation of cell cycleGO:004578730.023
protein localization to nucleusGO:003450430.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.022
macromolecule biosynthetic processGO:00090592270.022
ubiquitin dependent protein catabolic processGO:000651130.022
cellular biosynthetic processGO:00442492860.022
gtp catabolic processGO:000618420.022
muscle cell differentiationGO:00426921390.022
regulation of macromolecule metabolic processGO:00602553170.022
carboxylic acid metabolic processGO:0019752220.021
single organism transportGO:00447652060.021
regulation of peptidyl tyrosine phosphorylationGO:005073010.021
heart developmentGO:00075073130.021
positive regulation of exocytosisGO:004592110.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
establishment of protein localization to organelleGO:007259440.021
vasculature developmentGO:00019442780.021
regulation of signalingGO:00230512350.021
protein import into nucleusGO:000660630.021
regulation of cellular carbohydrate metabolic processGO:001067540.021
neuron developmentGO:00486662620.021
localization of cellGO:00516742440.021
gtp metabolic processGO:004603940.021
stem cell divisionGO:001714510.021
protein secretionGO:000930610.020
nuclear transportGO:005116940.020
carbohydrate derivative biosynthetic processGO:1901137430.020
stem cell proliferationGO:007208940.020
positive regulation of cytoskeleton organizationGO:005149530.020
nitrogen compound metabolic processGO:00068073190.020
cellular amino acid metabolic processGO:000652070.020
regulation of protein catabolic processGO:004217610.020
positive regulation of blood circulationGO:190352420.020
cellular ketone metabolic processGO:0042180110.020
regulation of nitrogen compound metabolic processGO:00511712510.020
positive regulation of cellular amine metabolic processGO:003324000.020
pigmentationGO:0043473850.020
negative regulation of protein phosphorylationGO:000193340.020
golgi vesicle transportGO:004819330.020
regulation of protein import into nucleusGO:004230620.020
organelle organizationGO:00069962270.020
nuclear migrationGO:000709730.020
embryonic organ morphogenesisGO:00485622740.020
organic cyclic compound biosynthetic processGO:19013622230.019
nucleocytoplasmic transportGO:000691340.019
ameboidal type cell migrationGO:00016671430.019
regulation of multicellular organism growthGO:004001440.019
adherens junction organizationGO:003433240.019
regulation of erk1 and erk2 cascadeGO:007037240.019
inner ear developmentGO:00488391260.019
muscle structure developmentGO:00610611960.019
extrinsic apoptotic signaling pathwayGO:009719130.019
protein metabolic processGO:00195381830.019
rna localizationGO:000640340.019
embryonic organ developmentGO:00485683810.019
ear developmentGO:00435831270.019
symbiosis encompassing mutualism through parasitismGO:004440340.018
cell motilityGO:00488702440.018
cellular localizationGO:0051641970.018
cellular aromatic compound metabolic processGO:00067252950.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
hormone secretionGO:004687920.018
response to drugGO:004249330.018
protein importGO:001703830.018
intracellular signal transductionGO:0035556850.018
eye morphogenesisGO:00485921440.018
cytokinesisGO:000091030.018
regulation of bindingGO:005109830.018
modification dependent macromolecule catabolic processGO:004363230.018
phototransductionGO:000760220.018
regulation of cell deathGO:00109411030.018
membrane invaginationGO:001032410.018
single organism organelle organizationGO:19025891990.018
somatic muscle developmentGO:000752540.018
i kappab kinase nf kappab signalingGO:000724940.018
positive regulation of nucleoside metabolic processGO:004597910.018
germ line stem cell maintenanceGO:003071820.018
phagocytosisGO:000690930.018
regulation of protein complex assemblyGO:004325430.018
organic cyclic compound metabolic processGO:19013603010.018
cell morphogenesisGO:00009022890.017
regulation of purine nucleotide catabolic processGO:003312120.017
protein targeting to nucleusGO:004474430.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
oxoacid metabolic processGO:0043436310.017
synaptic growth at neuromuscular junctionGO:005112420.017
cellular nitrogen compound metabolic processGO:00346412900.017
protein localization to plasma membraneGO:007265910.017
regulation of cytokine productionGO:000181730.017
regulation of protein targetingGO:190353320.017
nuclear importGO:005117030.017
regulation of nucleoside metabolic processGO:000911820.017
positive regulation of epithelial cell differentiationGO:003085820.017
organic acid metabolic processGO:0006082310.017
meiotic nuclear divisionGO:000712640.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
compound eye developmentGO:004874920.016
brain developmentGO:00074202930.016
negative regulation of catabolic processGO:000989530.016
cellular component disassemblyGO:002241110.016
regulation of nucleotide catabolic processGO:003081120.016
negative regulation of biological processGO:00485193040.016
regulation of response to stimulusGO:00485832690.016
mitochondrion organizationGO:000700540.016
cilium movementGO:0003341260.016
hormone transportGO:000991420.016
autophagyGO:000691440.016
regulation of signal transductionGO:00099662250.016
establishment of localization in cellGO:0051649770.016
regulation of programmed cell deathGO:00430671010.016
regulation of biological qualityGO:00650082630.016
positive regulation of cell activationGO:005086710.016
interspecies interaction between organismsGO:004441940.016
cellular nitrogen compound biosynthetic processGO:00442712180.016
antimicrobial humoral responseGO:001973020.016
regulation of cell activationGO:005086510.015
negative regulation of protein transportGO:005122430.015
neurotransmitter transportGO:000683620.015
regulation of nucleocytoplasmic transportGO:004682220.015
cellular response to external stimulusGO:007149620.015
actin polymerization or depolymerizationGO:000815420.015
regulation of ion transmembrane transporter activityGO:003241220.015
organic substance biosynthetic processGO:19015762890.015
cellular protein metabolic processGO:00442671290.015
cognitionGO:005089010.015
intracellular mrna localizationGO:000829810.015
response to uvGO:000941130.015
morphogenesis of an epitheliumGO:00020093330.015
muscle cell developmentGO:00550011150.015
positive regulation of immune effector processGO:000269930.015
single organism membrane fusionGO:004480120.015
ribonucleoside monophosphate catabolic processGO:000915840.015
neuron projection developmentGO:00311751800.015
single organism nuclear importGO:190259330.015
regulation of tube sizeGO:003515020.015
neuroblast proliferationGO:000740520.015
proteasomal protein catabolic processGO:001049820.015
positive regulation of protein complex assemblyGO:003133420.015
glycosylationGO:0070085110.015
regulation of biosynthetic processGO:00098892500.015
regulation of protein ubiquitinationGO:003139630.015
oocyte anterior posterior axis specificationGO:000731440.015
transcription dna templatedGO:00063511810.015
negative regulation of mapk cascadeGO:004340940.015
sensory organ morphogenesisGO:00905962000.015
phagocytosis engulfmentGO:000691110.014
organonitrogen compound metabolic processGO:1901564740.014
macromolecule modificationGO:00434121110.014
regulation of gtp catabolic processGO:003312420.014
cell projection organizationGO:00300302840.014
membrane fusionGO:006102520.014
regulation of cytoplasmic transportGO:190364940.014
secondary metabolic processGO:001974830.014
regulation of macromolecule biosynthetic processGO:00105562250.014
gene expressionGO:00104672520.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
regulation of production of molecular mediator of immune responseGO:000270010.014
deathGO:00162651210.014
cellular macromolecule metabolic processGO:00442603910.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
regulation of stem cell differentiationGO:200073640.014
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.014
positive regulation of gtpase activityGO:004354710.014
neurological system processGO:0050877620.014
macromolecule glycosylationGO:004341390.014
phosphate containing compound metabolic processGO:00067961080.014
negative regulation of cellular processGO:00485232830.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
protein modification processGO:00362111000.014
cell substrate adhesionGO:003158940.014
tissue remodelingGO:004877140.014
small molecule metabolic processGO:0044281770.014
rna metabolic processGO:00160702190.014
cellular response to chemical stimulusGO:00708871570.014
atp catabolic processGO:000620040.014
organelle fusionGO:004828430.014
leukocyte proliferationGO:007066110.014
positive regulation of nucleotide catabolic processGO:003081310.014
cellular protein modification processGO:00064641000.014
cellular macromolecule biosynthetic processGO:00346452240.014
synaptic vesicle localizationGO:009747910.014
cytoplasm organizationGO:000702840.014
meiotic cell cycle processGO:190304630.014
regulation of reproductive processGO:200024140.013
negative regulation of kinase activityGO:003367340.013
xenobiotic metabolic processGO:000680540.013
negative regulation of protein kinase activityGO:000646940.013
erk1 and erk2 cascadeGO:007037140.013
myeloid cell differentiationGO:0030099860.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
central nervous system developmentGO:00074173870.013
spermatid developmentGO:000728620.013
regulation of circadian rhythmGO:004275240.013
cellular response to hypoxiaGO:007145610.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
response to woundingGO:00096111160.013
regulation of blood vessel sizeGO:005088020.013
apoptotic processGO:00069151160.013
regulation of protein polymerizationGO:003227120.013
immune system processGO:00023762410.013
cell deathGO:00082191210.013
regulation of transmembrane transporter activityGO:002289820.013
phosphatidylinositol 3 kinase signalingGO:001406520.013
peptidyl serine phosphorylationGO:001810510.013
regulation of response to biotic stimulusGO:000283120.013
regulation of cell shapeGO:000836010.013
production of molecular mediator of immune responseGO:000244020.013
response to alkaloidGO:004327920.013
regulation of neural precursor cell proliferationGO:200017730.013
cellular response to decreased oxygen levelsGO:003629410.013
negative regulation of cell communicationGO:0010648960.012
multi organism cellular processGO:004476420.012
urogenital system developmentGO:0001655970.012
developmental pigmentationGO:0048066480.012
programmed cell deathGO:00125011190.012
negative regulation of signalingGO:0023057960.012
purine nucleoside monophosphate catabolic processGO:000912840.012
regulation of metal ion transportGO:001095940.012
synaptic vesicle transportGO:004848910.012
wound healingGO:0042060900.012
erythrocyte homeostasisGO:0034101550.012
b cell activationGO:004211320.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
endosomal transportGO:001619720.012
positive regulation of gtp catabolic processGO:003312610.012
cell killingGO:000190620.012
regulation of multicellular organismal developmentGO:20000262230.012
striated muscle cell developmentGO:00550021080.012
transcription from rna polymerase ii promoterGO:0006366800.012
determination of left right symmetryGO:00073681790.012
alcohol biosynthetic processGO:004616520.012
cellular response to lipopolysaccharideGO:007122230.012
positive regulation of cell adhesionGO:004578510.012
cellular response to oxygen levelsGO:007145310.012
regulation of mrna processingGO:005068430.012
aromatic compound biosynthetic processGO:00194382170.012
energy reserve metabolic processGO:000611220.012
cellular response to molecule of bacterial originGO:007121930.012
negative regulation of map kinase activityGO:004340720.012
leukocyte mediated cytotoxicityGO:000190910.012
regulation of apoptotic processGO:0042981980.012
locomotionGO:00400113130.012
positive regulation of neuron deathGO:190121610.012
nucleobase containing compound biosynthetic processGO:00346542050.011
microtubule based processGO:0007017600.011
nucleic acid metabolic processGO:00903042440.011
regulation of exocytosisGO:001715710.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
nucleoside monophosphate catabolic processGO:000912540.011
positive regulation of protein polymerizationGO:003227320.011
regulation of gtpase activityGO:004308720.011
viral processGO:001603210.011
pole plasm assemblyGO:000731540.011
actin filament polymerizationGO:003004120.011
macromolecular complex disassemblyGO:003298410.011
protein complex disassemblyGO:004324110.011
cell projection morphogenesisGO:00488582440.011
carbohydrate derivative metabolic processGO:1901135610.011
skeletal system developmentGO:00015011810.011
nucleobase containing compound metabolic processGO:00061392740.011
response to hexoseGO:000974630.011
response to carbohydrateGO:000974330.011
digestive system developmentGO:00551232890.011
regulation of cellular protein catabolic processGO:190336210.011
heme metabolic processGO:004216890.011
cell morphogenesis involved in differentiationGO:00009041950.011
peptide metabolic processGO:000651810.011
post embryonic organ developmentGO:004856940.011
centrosome organizationGO:005129710.011
regulation of cell projection assemblyGO:006049140.011
maternal determination of anterior posterior axis embryoGO:000835840.011
multicellular organismal response to stressGO:003355520.011
tube morphogenesisGO:00352393490.011
cellular response to starvationGO:000926710.011
liver developmentGO:0001889960.011
protein dephosphorylationGO:000647030.011
establishment of synaptic vesicle localizationGO:009748010.011
startle responseGO:000196440.011
rna transportGO:005065820.011
sleepGO:003043110.011
positive regulation of epithelial cell migrationGO:001063420.011
phosphatidylinositol mediated signalingGO:004801520.010
positive regulation of cell divisionGO:005178120.010
negative regulation of intracellular protein transportGO:009031730.010
response to corticosteroidGO:003196010.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
peptide transportGO:001583310.010
negative regulation of multi organism processGO:004390130.010
cellular response to extracellular stimulusGO:003166820.010
nucleic acid templated transcriptionGO:00976591810.010
protein complex localizationGO:003150310.010
regulation of calcium ion transportGO:005192420.010
establishment of protein localization to plasma membraneGO:009000210.010
regulation of neuronal synaptic plasticityGO:004816810.010
regulation of cellular macromolecule biosynthetic processGO:20001122220.010
small molecule catabolic processGO:004428230.010
regulation of cellular biosynthetic processGO:00313262450.010
regulation of dendrite morphogenesisGO:004881430.010
lateral inhibitionGO:004633110.010
calcium ion dependent exocytosisGO:001715610.010
cell matrix adhesionGO:000716040.010
chordate embryonic developmentGO:00430092710.010
regulation of epithelial cell proliferationGO:005067830.010

fgf21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.061
immune system diseaseDOID:291400.027
musculoskeletal system diseaseDOID:1700.017
disease of metabolismDOID:001466700.016
muscle tissue diseaseDOID:6600.016
myopathyDOID:42300.016
muscular diseaseDOID:008000000.016
nervous system diseaseDOID:86300.015
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.012
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011