Danio rerio

30 known processes

ptpn11b

protein tyrosine phosphatase, non-receptor type 11, b

(Aliases: zgc:63553,MGC63553)

ptpn11b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
endocrine processGO:005088620.252
multicellular organism growthGO:003526440.164
cognitionGO:005089010.144
protein import into nucleusGO:000660630.132
skeletal system developmentGO:00015011810.131
amine metabolic processGO:000930820.128
positive regulation of cell cycleGO:004578730.115
system processGO:00030081850.110
nuclear transportGO:005116940.107
cellular carbohydrate metabolic processGO:004426240.107
negative regulation of biological processGO:00485193040.100
actin polymerization or depolymerizationGO:000815420.094
protein targeting to nucleusGO:004474430.093
regulation of erk1 and erk2 cascadeGO:007037240.091
regulation of synaptic plasticityGO:004816710.084
response to stressGO:00069502630.083
regulation of establishment of protein localizationGO:007020140.082
establishment of protein localization to organelleGO:007259440.081
nucleocytoplasmic transportGO:000691340.081
digestive system developmentGO:00551232890.079
steroid hormone secretionGO:003592910.079
regulation of cell communicationGO:00106462320.078
regulation of protein targetingGO:190353320.073
regulation of multicellular organism growthGO:004001440.073
blood vessel developmentGO:00015682460.070
digestive tract developmentGO:00485652650.069
endocrine hormone secretionGO:006098620.069
regulation of protein transportGO:005122330.067
regulation of cellular carbohydrate metabolic processGO:001067540.066
maintenance of locationGO:005123540.065
embryonic skeletal system developmentGO:0048706970.065
regulation of intracellular protein transportGO:003315730.064
protein localization to nucleusGO:003450430.064
single organism nuclear importGO:190259330.062
cellular amine metabolic processGO:004410620.062
positive regulation of cytoskeleton organizationGO:005149530.061
protein importGO:001703830.061
regulation of endocrine processGO:004406020.059
agingGO:000756820.058
cell surface receptor signaling pathwayGO:00071663250.056
response to organic substanceGO:00100331530.055
regulation of circadian rhythmGO:004275240.054
regulation of signalingGO:00230512350.054
regulation of signal transductionGO:00099662250.054
cellular macromolecule metabolic processGO:00442603910.054
myeloid cell differentiationGO:0030099860.053
regulation of cytoplasmic transportGO:190364940.053
hormone transportGO:000991420.052
single organism metabolic processGO:00447102170.052
neurotransmitter transportGO:000683620.052
synaptic vesicle localizationGO:009747910.051
cell part morphogenesisGO:00329902460.050
peptide transportGO:001583310.050
protein metabolic processGO:00195381830.049
vasculature developmentGO:00019442780.049
neuron differentiationGO:00301823530.048
cellular nitrogen compound metabolic processGO:00346412900.048
locomotor rhythmGO:004547530.048
regulation of cellular amine metabolic processGO:003323800.048
cellular component movementGO:00069283350.047
chordate embryonic developmentGO:00430092710.047
glucose homeostasisGO:004259310.046
developmental growthGO:00485891660.045
single organism organelle organizationGO:19025891990.045
signal transductionGO:00071654550.045
carbohydrate homeostasisGO:003350010.045
regulation of hormone secretionGO:004688320.045
cellular protein catabolic processGO:004425740.044
regulation of peptidyl tyrosine phosphorylationGO:005073010.044
embryo development ending in birth or egg hatchingGO:00097922710.043
regulation of reactive oxygen species metabolic processGO:200037720.042
lipid storageGO:001991510.042
neurotransmitter secretionGO:000726920.042
regulation of response to stimulusGO:00485832690.041
regulation of nucleocytoplasmic transportGO:004682220.041
cellular aromatic compound metabolic processGO:00067252950.040
gtp catabolic processGO:000618420.040
extrinsic apoptotic signaling pathwayGO:009719130.040
cellular amino acid metabolic processGO:000652070.040
intracellular signal transductionGO:0035556850.040
protein dephosphorylationGO:000647030.039
embryonic skeletal system morphogenesisGO:0048704930.039
digestive tract morphogenesisGO:00485462310.039
multicellular organismal response to stressGO:003355520.038
ear developmentGO:00435831270.038
convergent extensionGO:00600261180.038
tube morphogenesisGO:00352393490.038
response to drugGO:004249330.037
regulation of cellular ketone metabolic processGO:001056570.037
negative regulation of kinase activityGO:003367340.037
neuron projection developmentGO:00311751800.037
positive regulation of cellular component biogenesisGO:004408930.037
neuron developmentGO:00486662620.037
regulation of cellular amino acid metabolic processGO:000652100.037
phagocytosis engulfmentGO:000691110.036
organonitrogen compound metabolic processGO:1901564740.036
larval developmentGO:000216420.036
cell projection organizationGO:00300302840.036
negative regulation of cytoplasmic transportGO:190365020.036
regulation of response to nutrient levelsGO:003210710.035
exocytosisGO:000688710.035
energy reserve metabolic processGO:000611220.035
nuclear importGO:005117030.035
cytoskeleton dependent cytokinesisGO:006164030.034
guanosine containing compound metabolic processGO:190106840.034
positive regulation of striated muscle cell differentiationGO:005115510.033
negative regulation of cellular processGO:00485232830.033
regulation of glucose transportGO:001082710.033
macroautophagyGO:001623610.033
regulation of wound healingGO:006104120.033
chemosensory behaviorGO:000763510.033
regulation of protein localization to nucleusGO:190018020.033
protein polymerizationGO:005125840.032
adult behaviorGO:003053420.032
mesoderm developmentGO:0007498880.032
germ line stem cell maintenanceGO:003071820.032
negative regulation of protein import into nucleusGO:004230820.032
cytokinesisGO:000091030.032
regulation of nucleotide catabolic processGO:003081120.031
response to amino acidGO:004320020.031
macromolecule biosynthetic processGO:00090592270.031
embryonic cranial skeleton morphogenesisGO:0048701900.031
regulation of protein import into nucleusGO:004230620.031
regulation of cytokine productionGO:000181730.031
fertilizationGO:000956630.031
negative regulation of map kinase activityGO:004340720.031
negative regulation of protein kinase activityGO:000646940.030
single fertilizationGO:000733830.030
sensory system developmentGO:0048880760.030
organelle assemblyGO:00709251100.030
cellular response to stressGO:0033554620.030
regionalizationGO:00030022740.030
regulation of carbohydrate metabolic processGO:000610940.030
neuron neuron synaptic transmissionGO:000727010.030
negative regulation of intracellular transportGO:003238730.030
negative regulation of protein transportGO:005122430.029
blood vessel morphogenesisGO:00485142160.029
proteasomal protein catabolic processGO:001049820.029
response to woundingGO:00096111160.029
nitrogen compound metabolic processGO:00068073190.029
modification dependent macromolecule catabolic processGO:004363230.028
regulation of response to extracellular stimulusGO:003210410.028
locomotionGO:00400113130.028
cellular ketone metabolic processGO:0042180110.028
response to radiationGO:0009314510.028
regulation of metabolic processGO:00192223590.028
myeloid cell developmentGO:0061515320.028
lateral line developmentGO:0048882660.028
positive regulation of signal transductionGO:0009967560.028
positive regulation of transportGO:005105020.028
positive regulation of map kinase activityGO:004340630.028
glucose importGO:004632320.028
organic substance biosynthetic processGO:19015762890.028
oxoacid metabolic processGO:0043436310.028
embryonic organ morphogenesisGO:00485622740.027
regulation of autophagyGO:001050630.027
programmed cell deathGO:00125011190.027
regulation of cellular metabolic processGO:00313233200.027
phosphate containing compound metabolic processGO:00067961080.027
nuclear exportGO:005116810.027
cellular response to nutrient levelsGO:003166920.027
erk1 and erk2 cascadeGO:007037140.027
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.027
nitrogen compound transportGO:0071705230.027
positive regulation of secretion by cellGO:190353210.026
regulation of gtp catabolic processGO:003312420.026
ameboidal type cell migrationGO:00016671430.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
cellular component assembly involved in morphogenesisGO:00109271070.026
skeletal system morphogenesisGO:00487051020.026
enzyme linked receptor protein signaling pathwayGO:00071671060.026
guanosine containing compound catabolic processGO:190106920.026
stem cell maintenanceGO:001982740.026
establishment of synaptic vesicle localizationGO:009748010.026
carbohydrate biosynthetic processGO:001605110.026
olfactory bulb developmentGO:002177240.026
phagocytosisGO:000690930.026
cellular response to extracellular stimulusGO:003166820.025
growthGO:00400071740.025
regulation of developmental processGO:00507932470.025
organelle localizationGO:0051640490.025
negative regulation of catabolic processGO:000989530.025
negative regulation of protein phosphorylationGO:000193340.025
cellular response to external stimulusGO:007149620.025
regulation of multicellular organismal processGO:00512392770.025
negative regulation of protein serine threonine kinase activityGO:007190120.025
response to endogenous stimulusGO:0009719830.025
negative regulation of intracellular protein transportGO:009031730.024
response to uvGO:000941130.024
inner ear developmentGO:00488391260.024
membrane invaginationGO:001032410.024
organism emergence from protective structureGO:007168440.024
cellular modified amino acid metabolic processGO:000657530.024
cellular protein metabolic processGO:00442671290.024
stem cell differentiationGO:00488631170.024
embryonic viscerocranium morphogenesisGO:0048703520.024
protein acylationGO:004354330.024
response to carbohydrateGO:000974330.024
synaptic growth at neuromuscular junctionGO:005112420.024
actin filament polymerizationGO:003004120.024
calcium ion dependent exocytosisGO:001715610.024
gastrulationGO:00073692080.024
positive regulation of cellular amine metabolic processGO:003324000.024
positive regulation of erk1 and erk2 cascadeGO:007037420.024
regulation of synapse assemblyGO:005196330.023
endosomal transportGO:001619720.023
lateral line system developmentGO:0048925760.023
pronuclear migrationGO:003504610.023
cilium morphogenesisGO:0060271850.023
localization of cellGO:00516742440.023
positive regulation of biological processGO:00485182530.023
ubiquitin dependent protein catabolic processGO:000651130.023
positive regulation of protein complex assemblyGO:003133420.023
i kappab kinase nf kappab signalingGO:000724940.023
epithelial tube morphogenesisGO:00605621480.023
sensory organ developmentGO:00074233930.023
positive regulation of catabolic processGO:000989640.023
regulation of nitrogen compound metabolic processGO:00511712510.023
transportGO:00068102200.022
angiogenesisGO:00015251580.022
multi organism cellular processGO:004476420.022
regulation of jak stat cascadeGO:004642530.022
positive regulation of cellular processGO:00485222010.022
carboxylic acid metabolic processGO:0019752220.022
cellular response to starvationGO:000926710.022
positive regulation of cell divisionGO:005178120.022
mitochondrion organizationGO:000700540.022
heart developmentGO:00075073130.022
single organism transportGO:00447652060.022
cellular nitrogen compound biosynthetic processGO:00442712180.022
modification dependent protein catabolic processGO:001994130.022
regulation of biological qualityGO:00650082630.022
cell migrationGO:00164772370.022
mesenchyme developmentGO:00604851270.022
negative regulation of nucleocytoplasmic transportGO:004682320.021
positive regulation of apoptotic signaling pathwayGO:200123510.021
wnt signaling pathwayGO:0016055800.021
neuromast developmentGO:0048884460.021
positive regulation of response to stimulusGO:0048584800.021
regulation of glucose importGO:004632410.021
negative regulation of cellular catabolic processGO:003133030.021
symbiosis encompassing mutualism through parasitismGO:004440340.021
reactive oxygen species metabolic processGO:007259360.020
positive regulation of small gtpase mediated signal transductionGO:005105710.020
immune system processGO:00023762410.020
gene expressionGO:00104672520.020
cartilage developmentGO:0051216960.020
peptidyl serine modificationGO:001820920.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
positive regulation of secretionGO:005104710.020
neurological system processGO:0050877620.020
rna localizationGO:000640340.020
brain developmentGO:00074202930.020
response to glucoseGO:000974930.020
organic cyclic compound metabolic processGO:19013603010.020
insulin like growth factor receptor signaling pathwayGO:004800940.019
homeostatic processGO:00425921420.019
gtp metabolic processGO:004603940.019
autophagyGO:000691440.019
monoamine transportGO:001584410.019
determination of left right symmetryGO:00073681790.019
response to monosaccharideGO:003428430.019
regulation of i kappab kinase nf kappab signalingGO:004312240.019
regulation of purine nucleotide catabolic processGO:003312120.019
female sex differentiationGO:004666040.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.019
organic substance transportGO:0071702580.019
multi organism processGO:00517041340.019
regulation of neurological system processGO:003164420.019
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.019
rna metabolic processGO:00160702190.019
negative regulation of mapk cascadeGO:004340940.019
somatic muscle developmentGO:000752540.019
cellular response to organic substanceGO:00713101050.019
response to hexoseGO:000974630.019
cilium organizationGO:0044782710.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
response to organic cyclic compoundGO:0014070510.019
response to chemicalGO:00422213200.018
cell deathGO:00082191210.018
regulation of nucleoside metabolic processGO:000911820.018
striated muscle cell developmentGO:00550021080.018
peptidyl serine phosphorylationGO:001810510.018
positive regulation of wound healingGO:009030310.018
regulation of protein ubiquitinationGO:003139630.018
cellular response to dna damage stimulusGO:0006974240.018
response to alkaloidGO:004327920.018
positive regulation of cellular catabolic processGO:003133130.018
positive regulation of canonical wnt signaling pathwayGO:009026340.018
olfactory lobe developmentGO:002198840.018
head developmentGO:00603223030.018
superoxide metabolic processGO:000680120.018
response to virusGO:0009615210.018
entrainment of circadian clockGO:000964920.018
morphogenesis of an epitheliumGO:00020093330.018
protein complex disassemblyGO:004324110.017
determination of heart left right asymmetryGO:00613711170.017
blood circulationGO:0008015870.017
cellular protein modification processGO:00064641000.017
cellular component biogenesisGO:00440851780.017
cellular response to decreased oxygen levelsGO:003629410.017
leukocyte proliferationGO:007066110.017
regulation of neuronal synaptic plasticityGO:004816810.017
regulation of protein complex assemblyGO:004325430.017
g protein coupled receptor signaling pathwayGO:0007186740.017
negative regulation of metabolic processGO:0009892860.017
negative regulation of multicellular organismal processGO:0051241690.017
regulation of intracellular signal transductionGO:1902531570.017
calcium mediated signalingGO:001972220.017
organic acid metabolic processGO:0006082310.017
regulation of cell substrate adhesionGO:001081010.017
nucleobase containing compound metabolic processGO:00061392740.017
positive regulation of ras protein signal transductionGO:004657910.017
negative regulation of cytokine productionGO:000181810.017
maternal determination of anterior posterior axis embryoGO:000835840.017
regulation of reproductive processGO:200024140.017
regulation of synapse organizationGO:005080730.017
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.016
regulation of cell cycleGO:0051726520.016
erythrocyte differentiationGO:0030218540.016
convergent extension involved in gastrulationGO:0060027710.016
regulation of macromolecule metabolic processGO:00602553170.016
regulation of blood pressureGO:000821710.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
negative regulation of epithelial cell proliferationGO:005068010.016
positive regulation of cytokine productionGO:000181920.016
signal transduction by phosphorylationGO:0023014180.016
mitotic cytokinesisGO:000028130.016
carbohydrate metabolic processGO:0005975120.016
neuron projection morphogenesisGO:00488121610.016
cell morphogenesis involved in neuron differentiationGO:00486671630.016
regulation of microtubule cytoskeleton organizationGO:007050730.016
macromolecular complex disassemblyGO:003298410.016
amino acid transportGO:000686520.016
cellular amide metabolic processGO:004360340.016
regulation of receptor activityGO:001046920.016
ribosomal small subunit biogenesisGO:004227420.016
ras protein signal transductionGO:000726570.015
eye developmentGO:00016542770.015
cellular response to endogenous stimulusGO:0071495680.015
regulation of stem cell proliferationGO:007209120.015
positive regulation of signalingGO:0023056560.015
regulation of neurotransmitter transportGO:005158810.015
circadian regulation of gene expressionGO:003292280.015
transcription dna templatedGO:00063511810.015
internal peptidyl lysine acetylationGO:001839320.015
regulation of protein catabolic processGO:004217610.015
response to hormoneGO:0009725480.015
response to abiotic stimulusGO:00096281220.015
signal transduction in absence of ligandGO:003803410.015
regulation of gene expressionGO:00104682650.015
wound healingGO:0042060900.015
ion transportGO:00068111140.015
synaptic vesicle recyclingGO:003646510.015
regulation of oocyte developmentGO:006028130.015
cell projection morphogenesisGO:00488582440.015
connective tissue developmentGO:0061448990.015
cell motilityGO:00488702440.015
positive regulation of protein kinase b signalingGO:005189710.015
meiotic nuclear divisionGO:000712640.015
regulation of biosynthetic processGO:00098892500.015
protein complex localizationGO:003150310.015
positive regulation of cell activationGO:005086710.015
regulation of cell deathGO:00109411030.015
liver developmentGO:0001889960.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
protein modification processGO:00362111000.015
chemical homeostasisGO:0048878490.015
negative regulation of signal transductionGO:0009968940.015
negative regulation of secretionGO:005104820.014
adherens junction organizationGO:003433240.014
regulation of cell activationGO:005086510.014
pole plasm assemblyGO:000731540.014
small molecule metabolic processGO:0044281770.014
regulation of lipid transportGO:003236840.014
anterior posterior pattern specificationGO:00099521520.014
small gtpase mediated signal transductionGO:000726480.014
lipid catabolic processGO:001604240.014
stem cell proliferationGO:007208940.014
central nervous system developmentGO:00074173870.014
cell cycle processGO:0022402530.014
sensory organ morphogenesisGO:00905962000.014
golgi vesicle transportGO:004819330.014
erythrocyte homeostasisGO:0034101550.014
centrosome duplicationGO:005129810.014
negative regulation of secretion by cellGO:190353120.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
positive regulation of jak stat cascadeGO:004642720.014
catecholamine metabolic processGO:000658420.014
oocyte anterior posterior axis specificationGO:000731440.014
sprouting angiogenesisGO:0002040530.014
positive regulation of epithelial cell migrationGO:001063420.014
cytoskeleton organizationGO:0007010960.014
hepaticobiliary system developmentGO:0061008980.014
regulation of phGO:000688530.014
muscle structure developmentGO:00610611960.014
negative regulation of cell communicationGO:0010648960.014
development of primary female sexual characteristicsGO:004654540.014
positive regulation of protein polymerizationGO:003227320.014
multicellular organismal metabolic processGO:004423620.013
pigment granule aggregation in cell centerGO:005187780.013
circulatory system processGO:0003013870.013
spindle assemblyGO:005122520.013
regulation of primary metabolic processGO:00800903110.013
regulation of localizationGO:00328791040.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
regulation of epithelial cell proliferationGO:005067830.013
cell matrix adhesionGO:000716040.013
regulation of wnt signaling pathwayGO:0030111530.013
cell substrate junction assemblyGO:000704420.013
cellular response to hypoxiaGO:007145610.013
regulation of neurotransmitter secretionGO:004692810.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
transmembrane transportGO:00550851200.013
hormone secretionGO:004687920.013
positive regulation of striated muscle tissue developmentGO:004584410.013
regulation of transmembrane transporter activityGO:002289820.013
regulation of dendrite developmentGO:005077330.013
negative regulation of dna metabolic processGO:005105340.013
tissue remodelingGO:004877140.013
phosphorylationGO:0016310690.013
nucleic acid transportGO:005065720.013
eye morphogenesisGO:00485921440.013
positive regulation of immune effector processGO:000269930.013
behaviorGO:0007610740.012
regulation of protein polymerizationGO:003227120.012
regenerationGO:0031099910.012
dicarboxylic acid transportGO:000683510.012
positive regulation of muscle cell differentiationGO:005114910.012
cellular transition metal ion homeostasisGO:004691630.012
regulation of programmed cell deathGO:00430671010.012
nucleic acid metabolic processGO:00903042440.012
interspecies interaction between organismsGO:004441940.012
negative regulation of autophagyGO:001050710.012
single organism behaviorGO:0044708240.012
stem cell divisionGO:001714510.012
positive regulation of translationGO:004572710.012
transcription from rna polymerase ii promoterGO:0006366800.012
negative regulation of cell deathGO:0060548600.012
nuclear migrationGO:000709730.012
catechol containing compound metabolic processGO:000971220.012
heterocycle metabolic processGO:00464832900.012
negative regulation of signalingGO:0023057960.012
regulation of carbohydrate biosynthetic processGO:004325510.012
regulation of myotube differentiationGO:001083020.012
establishment of localization in cellGO:0051649770.012
cell adhesion mediated by integrinGO:003362710.012
regulation of protein bindingGO:004339330.012
cellular component morphogenesisGO:00329893360.012
hatchingGO:003518840.012
spindle assembly involved in mitosisGO:009030710.012
regulation of transportGO:0051049450.012
cell morphogenesis involved in differentiationGO:00009041950.012
peptidyl threonine phosphorylationGO:001810710.012
regulation of metal ion transportGO:001095940.012
negative regulation of protein localization to nucleusGO:190018120.012
negative regulation of ras protein signal transductionGO:004658010.012
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
urogenital system developmentGO:0001655970.012
regulation of membrane potentialGO:0042391230.012
peptidyl tyrosine modificationGO:001821250.012
peptidyl lysine trimethylationGO:001802310.012
cellular macromolecule biosynthetic processGO:00346452240.012
negative regulation of wnt signaling pathwayGO:0030178300.012
establishment of rna localizationGO:005123630.012
microtubule cytoskeleton organization involved in mitosisGO:190285010.012
mononuclear cell proliferationGO:003294310.011
aromatic compound biosynthetic processGO:00194382170.011
circadian rhythmGO:0007623190.011
regulation of apoptotic processGO:0042981980.011
regulation of erythrocyte differentiationGO:004564620.011
zymogen activationGO:003163830.011
response to light stimulusGO:0009416460.011
cellular component disassemblyGO:002241110.011
viral processGO:001603210.011
cellular response to biotic stimulusGO:007121630.011
positive regulation of cell adhesionGO:004578510.011
antimicrobial humoral responseGO:001973020.011
regulation of multicellular organismal developmentGO:20000262230.011
germ line stem cell divisionGO:004207810.011
cellular component assemblyGO:00226071700.011
intracellular mrna localizationGO:000829810.011
fatty acid transportGO:001590810.011

ptpn11b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.116
nervous system diseaseDOID:86300.032
disease of cellular proliferationDOID:1456600.027
organ system cancerDOID:005068600.027
cancerDOID:16200.027
disease of metabolismDOID:001466700.017
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012
sensory system diseaseDOID:005015500.012
inherited metabolic disorderDOID:65500.012
retinal diseaseDOID:567900.012