Danio rerio

0 known processes

sema6dl

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like

(Aliases: si:ch211-278n20.1,zgc:112012)

sema6dl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cellular processGO:00485232830.443
Mouse
carbohydrate derivative metabolic processGO:1901135610.342
signal transductionGO:00071654550.321
Fly
cell surface receptor signaling pathwayGO:00071663250.303
Fly
neuron projection morphogenesisGO:00488121610.293
Zebrafish Fly
positive regulation of cellular processGO:00485222010.287
Mouse
localization of cellGO:00516742440.250
Zebrafish Mouse
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.229
negative regulation of cell projection organizationGO:003134590.227
cell projection morphogenesisGO:00488582440.227
Zebrafish Fly
mesenchyme developmentGO:00604851270.221
Zebrafish
cellular component movementGO:00069283350.213
Zebrafish Mouse Fly
locomotionGO:00400113130.206
Zebrafish Mouse Fly
nitrogen compound metabolic processGO:00068073190.205
stem cell developmentGO:0048864820.205
Zebrafish
regulation of cellular biosynthetic processGO:00313262450.198
embryonic organ developmentGO:00485683810.190
Zebrafish
cellular aromatic compound metabolic processGO:00067252950.177
negative regulation of biological processGO:00485193040.159
Mouse
peripheral nervous system neuron differentiationGO:0048934280.158
Zebrafish
nucleobase containing compound metabolic processGO:00061392740.153
regulation of metabolic processGO:00192223590.152
aromatic compound biosynthetic processGO:00194382170.134
cell motilityGO:00488702440.134
Zebrafish Mouse
chordate embryonic developmentGO:00430092710.134
Zebrafish
blood vessel morphogenesisGO:00485142160.133
Zebrafish
regulation of protein modification by small protein conjugation or removalGO:190332030.132
small molecule metabolic processGO:0044281770.131
embryonic skeletal system developmentGO:0048706970.129
Zebrafish
ameboidal type cell migrationGO:00016671430.127
Zebrafish
response to hypoxiaGO:0001666250.125
branching morphogenesis of a nerveGO:004875540.123
Zebrafish
brain developmentGO:00074202930.123
Zebrafish Mouse Fly
cell migrationGO:00164772370.119
Zebrafish Mouse
regulation of protein ubiquitinationGO:003139630.117
cellular nitrogen compound metabolic processGO:00346412900.114
response to oxygen levelsGO:0070482250.109
cellular response to oxygen levelsGO:007145310.108
regulation of reproductive processGO:200024140.102
axon developmentGO:00615641660.102
Zebrafish Fly
cell morphogenesis involved in differentiationGO:00009041950.101
Zebrafish Fly
cell substrate adhesionGO:003158940.100
neurological system processGO:0050877620.099
Fly
positive regulation of biological processGO:00485182530.090
Mouse
response to external stimulusGO:00096052640.089
Zebrafish Fly
peripheral nervous system developmentGO:0007422550.086
Zebrafish
single organism metabolic processGO:00447102170.085
peptidyl serine phosphorylationGO:001810510.082
stem cell differentiationGO:00488631170.080
Zebrafish
stem cell maintenanceGO:001982740.075
hair cell differentiationGO:0035315320.075
developmental cell growthGO:0048588520.075
Zebrafish
tube closureGO:006060610.073
cellular amino acid metabolic processGO:000652070.073
cell adhesionGO:0007155400.073
modification dependent macromolecule catabolic processGO:004363230.073
regulation of molecular functionGO:0065009700.071
regulation of signal transductionGO:00099662250.071
positive regulation of cell cycleGO:004578730.070
embryo development ending in birth or egg hatchingGO:00097922710.069
Zebrafish
regulation of protein targetingGO:190353320.067
neuron projection guidanceGO:0097485860.065
Zebrafish Fly
cellular component assemblyGO:00226071700.065
Fly
organonitrogen compound metabolic processGO:1901564740.064
neuroblast proliferationGO:000740520.064
cellular amine metabolic processGO:004410620.062
startle responseGO:000196440.061
Fly
cellular response to hypoxiaGO:007145610.061
regulation of collateral sprouting in absence of injuryGO:004869640.060
mesenchymal cell developmentGO:0014031780.060
Zebrafish
astrocyte differentiationGO:004870810.059
skeletal system developmentGO:00015011810.059
Zebrafish
macromolecule biosynthetic processGO:00090592270.059
head developmentGO:00603223030.058
Zebrafish Mouse Fly
modification dependent protein catabolic processGO:001994130.058
regulation of cell communicationGO:00106462320.058
somite developmentGO:0061053960.057
neuron projection developmentGO:00311751800.057
Zebrafish Fly
neuron developmentGO:00486662620.057
Zebrafish Fly
regulation of cellular metabolic processGO:00313233200.057
organic cyclic compound biosynthetic processGO:19013622230.057
organonitrogen compound biosynthetic processGO:1901566470.057
regulation of intracellular protein transportGO:003315730.057
response to decreased oxygen levelsGO:0036293250.056
regulation of cellular amine metabolic processGO:003323800.056
regulation of cell cycleGO:0051726520.055
Zebrafish
regulation of protein localization to nucleusGO:190018020.054
muscle cell differentiationGO:00426921390.053
regulation of primary metabolic processGO:00800903110.052
negative regulation of neuron differentiationGO:0045665100.052
positive regulation of transportGO:005105020.051
central nervous system developmentGO:00074173870.050
Zebrafish Mouse Fly
heart developmentGO:00075073130.050
Zebrafish
lipid catabolic processGO:001604240.050
amine metabolic processGO:000930820.050
regulation of gtp catabolic processGO:003312420.050
axon guidanceGO:0007411860.050
Zebrafish Fly
establishment of localizationGO:00512342440.050
regulation of oligodendrocyte differentiationGO:004871310.049
negative regulation of nervous system developmentGO:0051961220.049
organic cyclic compound metabolic processGO:19013603010.048
positive regulation of cell adhesionGO:004578510.048
mechanoreceptor differentiationGO:0042490370.047
adult behaviorGO:003053420.047
stem cell proliferationGO:007208940.047
regulation of biosynthetic processGO:00098892500.047
regulation of response to stimulusGO:00485832690.047
Fly
rna metabolic processGO:00160702190.047
regulation of transcription from rna polymerase ii promoterGO:00063571140.046
cellular protein modification processGO:00064641000.045
collateral sprouting in absence of injuryGO:004866940.045
notch signaling pathwayGO:0007219350.045
neural crest cell differentiationGO:0014033720.045
Zebrafish
cellular component morphogenesisGO:00329893360.044
Zebrafish Fly
regulation of biological qualityGO:00650082630.044
Zebrafish Fly
peripheral nervous system neuron axonogenesisGO:0048936130.044
Zebrafish
regulation of sequestering of calcium ionGO:005128240.043
gtp catabolic processGO:000618420.043
vasculature developmentGO:00019442780.043
Zebrafish
cellular response to decreased oxygen levelsGO:003629410.043
nucleic acid metabolic processGO:00903042440.042
regulation of glial cell differentiationGO:004568540.042
regulation of cellular ketone metabolic processGO:001056570.041
neuron projection extensionGO:1990138450.041
Zebrafish
phagocytosisGO:000690930.041
regulation of multicellular organismal processGO:00512392770.040
Zebrafish Fly
developmental growthGO:00485891660.040
Zebrafish
regulation of cellular amino acid metabolic processGO:000652100.040
heterocycle metabolic processGO:00464832900.040
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.038
positive regulation of catabolic processGO:000989640.038
nucleobase containing compound biosynthetic processGO:00346542050.038
cellular ketone metabolic processGO:0042180110.037
axonogenesisGO:00074091520.037
Zebrafish Fly
regulation of dendrite morphogenesisGO:004881430.036
ribonucleotide metabolic processGO:0009259270.036
neuron neuron synaptic transmissionGO:000727010.035
regulation of peptidyl tyrosine phosphorylationGO:005073010.035
pancreatic d cell differentiationGO:000331120.034
proteolysis involved in cellular protein catabolic processGO:005160330.034
cellular protein catabolic processGO:004425740.034
regulation of nucleotide catabolic processGO:003081120.033
ubiquitin dependent protein catabolic processGO:000651130.033
regulation of protein import into nucleusGO:004230620.033
tyrosine phosphorylation of stat proteinGO:000726010.032
regulation of cell substrate adhesionGO:001081010.032
positive regulation of cellular amino acid metabolic processGO:004576400.032
negative regulation of axon guidanceGO:190266810.032
regulation of transcription dna templatedGO:00063552130.032
regulation of cell morphogenesis involved in differentiationGO:0010769380.032
Zebrafish Fly
regulation of purine nucleotide catabolic processGO:003312120.032
meiotic nuclear divisionGO:000712640.032
positive regulation of cellular catabolic processGO:003133130.032
muscle structure developmentGO:00610611960.032
regulation of cellular macromolecule biosynthetic processGO:20001122220.031
cellular biosynthetic processGO:00442492860.031
regulation of macromolecule metabolic processGO:00602553170.031
regulation of catalytic activityGO:0050790550.031
intracellular signal transductionGO:0035556850.031
regulation of cell motilityGO:2000145460.031
Mouse
cellular macromolecule metabolic processGO:00442603910.031
regulation of mrna splicing via spliceosomeGO:004802430.031
paraxial mesoderm developmentGO:004833980.031
regulation of gtpase activityGO:004308720.030
regulation of neuron projection developmentGO:0010975400.030
Zebrafish Fly
primary neural tube formationGO:001402010.029
regulation of mrna processingGO:005068430.029
regulation of cytoplasmic transportGO:190364940.029
cellular respirationGO:004533330.029
dendrite developmentGO:001635890.029
Fly
embryonic organ morphogenesisGO:00485622740.028
Zebrafish
regulation of cellular component movementGO:0051270550.028
Mouse Fly
maintenance of locationGO:005123540.028
peptidyl serine modificationGO:001820920.028
connective tissue developmentGO:0061448990.028
Zebrafish
macromolecule modificationGO:00434121110.028
nucleobase containing small molecule metabolic processGO:0055086320.027
regulation of signalingGO:00230512350.027
regulation of axonogenesisGO:0050770320.027
Zebrafish Fly
protein localization to nucleusGO:003450430.027
regulation of phosphate metabolic processGO:0019220430.027
oligodendrocyte differentiationGO:0048709230.027
gtp metabolic processGO:004603940.027
positive regulation of tyrosine phosphorylation of stat proteinGO:004253110.027
microtubule organizing center organizationGO:003102310.027
larval developmentGO:000216420.026
Zebrafish
positive regulation of nucleoside metabolic processGO:004597910.026
response to nutrientGO:000758430.026
regionalizationGO:00030022740.026
regulation of nucleoside metabolic processGO:000911820.026
axon extensionGO:0048675450.026
Zebrafish
agingGO:000756820.025
negative regulation of axon extension involved in axon guidanceGO:004884310.025
protein import into nucleusGO:000660630.025
nuclear importGO:005117030.025
regulation of dna templated transcription in response to stressGO:004362000.025
sequestering of metal ionGO:005123830.025
skeletal system morphogenesisGO:00487051020.025
Zebrafish
dopaminergic neuron differentiationGO:0071542140.025
mrna metabolic processGO:0016071200.025
organ formationGO:0048645170.025
single organism transportGO:00447652060.024
phosphorus metabolic processGO:00067931090.023
organic substance biosynthetic processGO:19015762890.023
neuron migrationGO:0001764220.023
erk1 and erk2 cascadeGO:007037140.022
guanosine containing compound metabolic processGO:190106840.022
regulation of nervous system developmentGO:0051960900.022
Zebrafish Fly
biosynthetic processGO:00090582940.022
dorsal ventral pattern formationGO:00099531250.022
negative regulation of protein phosphorylationGO:000193340.022
morphogenesis of an epitheliumGO:00020093330.022
Zebrafish
regulation of nucleobase containing compound metabolic processGO:00192192500.022
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.022
cell matrix adhesionGO:000716040.022
positive regulation of cellular biosynthetic processGO:0031328680.022
cell agingGO:000756920.022
tyrosine phosphorylation of stat3 proteinGO:004250310.022
positive regulation of signal transductionGO:0009967560.022
cellular amino acid biosynthetic processGO:000865220.021
positive regulation of macromolecule metabolic processGO:0010604930.021
regulation of cell deathGO:00109411030.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
regulation of protein transportGO:005122330.021
central nervous system myelinationGO:002201020.021
retinal ganglion cell axon guidanceGO:0031290350.021
Zebrafish
cell morphogenesisGO:00009022890.021
Zebrafish Fly
regulation of cell morphogenesisGO:0022604420.021
Zebrafish Fly
positive regulation of cell activationGO:005086710.021
regulation of nitrogen compound metabolic processGO:00511712510.020
gene expressionGO:00104672520.020
negative regulation of wnt signaling pathwayGO:0030178300.020
regulation of collateral sproutingGO:004867070.020
negative regulation of cell morphogenesis involved in differentiationGO:001077180.020
positive regulation of catalytic activityGO:0043085250.020
regulation of purine nucleotide metabolic processGO:1900542170.020
rna biosynthetic processGO:00327741810.020
response to abiotic stimulusGO:00096281220.020
nephron developmentGO:0072006310.020
regulation of nucleic acid templated transcriptionGO:19035062130.019
cellular protein metabolic processGO:00442671290.019
brain morphogenesisGO:0048854180.019
Fly
positive regulation of gliogenesisGO:001401520.019
response to organic substanceGO:00100331530.019
neural crest cell developmentGO:0014032620.019
Zebrafish
positive regulation of cellular amine metabolic processGO:003324000.019
regulation of microtubule cytoskeleton organizationGO:007050730.019
cell growthGO:0016049570.019
Zebrafish
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.019
retina development in camera type eyeGO:00600411460.019
cell cycle g1 s phase transitionGO:004484310.019
membrane invaginationGO:001032410.018
regulation of nucleotide metabolic processGO:0006140170.018
actin cytoskeleton organizationGO:0030036630.018
oxoacid metabolic processGO:0043436310.018
organic acid metabolic processGO:0006082310.018
response to osmotic stressGO:0006970110.018
cell cycleGO:0007049930.018
Zebrafish
regulation of gene expressionGO:00104682650.018
liver developmentGO:0001889960.018
negative regulation of developmental processGO:0051093650.018
extracellular matrix organizationGO:0030198270.018
establishment of localization in cellGO:0051649770.018
response to inorganic substanceGO:0010035380.018
regulation of fatty acid metabolic processGO:001921710.018
ribose phosphate biosynthetic processGO:0046390200.018
protein targeting to nucleusGO:004474430.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
phosphate containing compound metabolic processGO:00067961080.018
protein modification processGO:00362111000.017
negative regulation of response to stimulusGO:00485851040.017
cell part morphogenesisGO:00329902460.017
Zebrafish Fly
response to metal ionGO:0010038340.017
embryonic limb morphogenesisGO:003032620.017
epithelial tube morphogenesisGO:00605621480.017
Zebrafish
multi organism processGO:00517041340.017
regulation of cell migrationGO:0030334400.017
Mouse
positive regulation of signalingGO:0023056560.017
collateral sproutingGO:004866890.017
negative regulation of metabolic processGO:0009892860.017
response to stressGO:00069502630.016
Zebrafish
phagocytosis engulfmentGO:000691110.016
carbohydrate derivative biosynthetic processGO:1901137430.016
developmental growth involved in morphogenesisGO:0060560860.016
Zebrafish
inner ear receptor cell fate commitmentGO:006012040.016
positive regulation of cellular component biogenesisGO:004408930.016
proximal distal pattern formationGO:000995410.016
striated muscle cell differentiationGO:00511461290.016
phosphorylationGO:0016310690.016
locomotory behaviorGO:0007626340.016
Fly
cellular macromolecule biosynthetic processGO:00346452240.016
cellular response to extracellular stimulusGO:003166820.016
nucleic acid templated transcriptionGO:00976591810.016
regulation of wnt signaling pathwayGO:0030111530.016
regulation of multicellular organism growthGO:004001440.016
regulation of inflammatory responseGO:005072720.016
meiosis iGO:000712710.016
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.016
cyclic nucleotide metabolic processGO:0009187180.016
regulation of tyrosine phosphorylation of stat proteinGO:004250910.016
regulation of cell activationGO:005086510.016
lymphocyte proliferationGO:004665110.015
axonal defasciculationGO:000741420.015
regulation of localizationGO:00328791040.015
Mouse Fly
regulation of cell growthGO:0001558290.015
Zebrafish
multicellular organism growthGO:003526440.015
kidney developmentGO:0001822920.015
regulation of bindingGO:005109830.015
cellular carbohydrate metabolic processGO:004426240.015
positive regulation of metabolic processGO:00098931080.015
regulation of macromolecule biosynthetic processGO:00105562250.015
regulation of cell developmentGO:00602841000.015
Zebrafish Fly
cellular response to external stimulusGO:007149620.015
negative regulation of macromolecule metabolic processGO:0010605760.015
transcription from rna polymerase ii promoterGO:0006366800.015
negative regulation of protein kinase activityGO:000646940.015
response to chemicalGO:00422213200.015
Zebrafish Fly
eye developmentGO:00016542770.014
positive regulation of cell developmentGO:0010720250.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
transportGO:00068102200.014
negative regulation of cellular metabolic processGO:0031324770.014
inner ear morphogenesisGO:0042472630.014
negative regulation of cell deathGO:0060548600.014
sexual reproductionGO:0019953360.014
cellular component assembly involved in morphogenesisGO:00109271070.014
regulation of cell projection organizationGO:0031344440.014
Zebrafish Fly
system processGO:00030081850.014
Fly
establishment of protein localization to organelleGO:007259440.014
regulation of tube sizeGO:003515020.014
negative regulation of sequestering of calcium ionGO:005128340.014
positive regulation of cell substrate adhesionGO:001081110.014
response to monosaccharideGO:003428430.013
positive regulation of translationGO:004572710.013
sensory organ morphogenesisGO:00905962000.013
centrosome organizationGO:005129710.013
ear developmentGO:00435831270.013
carboxylic acid metabolic processGO:0019752220.013
electron transport chainGO:002290020.013
cognitionGO:005089010.013
cellular localizationGO:0051641970.013
regulation of ras gtpase activityGO:003231820.013
positive regulation of cell communicationGO:0010647560.013
positive regulation of striated muscle tissue developmentGO:004584410.013
sex determinationGO:000753010.013
biological adhesionGO:0022610400.013
sprouting angiogenesisGO:0002040530.013
regulation of rna biosynthetic processGO:20011412130.013
epidermal cell differentiationGO:0009913360.013
regulation of circadian rhythmGO:004275240.013
negative regulation of gliogenesisGO:001401410.013
intracellular receptor signaling pathwayGO:0030522300.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.013
myeloid cell differentiationGO:0030099860.013
lymphatic endothelial cell differentiationGO:006083610.013
regulation of lipid catabolic processGO:005099420.013
chromosome organizationGO:0051276310.013
mesoderm developmentGO:0007498880.013
negative regulation of axon extensionGO:003051770.012
kupffer s vesicle developmentGO:0070121500.012
regulation of transporter activityGO:003240920.012
negative regulation of dna replicationGO:000815620.012
sensory perception of chemical stimulusGO:000760630.012
nuclear transportGO:005116940.012
renal system developmentGO:0072001940.012
forebrain cell migrationGO:002188510.012
dendrite guidanceGO:007098300.012
neuron differentiationGO:00301823530.012
Zebrafish Fly
cell projection organizationGO:00300302840.012
Zebrafish Fly
urogenital system developmentGO:0001655970.012
embryonic skeletal system morphogenesisGO:0048704930.012
Zebrafish
determination of left right symmetryGO:00073681790.012
regulation of establishment of protein localizationGO:007020140.012
regulation of rac protein signal transductionGO:003502010.012
segmentationGO:0035282970.012
ras protein signal transductionGO:000726570.012
glial cell proliferationGO:001400940.012
negative regulation of cellular protein metabolic processGO:0032269160.012
regulation of gliogenesisGO:001401360.012
compound eye developmentGO:004874920.012
transcription dna templatedGO:00063511810.012
negative regulation of programmed cell deathGO:0043069580.012
peripheral nervous system neuron developmentGO:0048935220.012
Zebrafish
purine ribonucleotide metabolic processGO:0009150270.012
muscle attachmentGO:001620390.012
posttranscriptional regulation of gene expressionGO:0010608140.012
ribosomal small subunit biogenesisGO:004227420.012
positive regulation of neural precursor cell proliferationGO:200017910.012
regulation of hematopoietic progenitor cell differentiationGO:190153210.012
positive regulation of nucleotide catabolic processGO:003081310.012
regulation of programmed cell deathGO:00430671010.011
regulation of carbohydrate metabolic processGO:000610940.011
extrinsic apoptotic signaling pathwayGO:009719130.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
proteasomal protein catabolic processGO:001049820.011
sensory organ developmentGO:00074233930.011
intracellular transportGO:0046907320.011
cardiocyte differentiationGO:0035051440.011
Zebrafish
protein metabolic processGO:00195381830.011
positive regulation of molecular functionGO:0044093330.011
regulation of nucleocytoplasmic transportGO:004682220.011
protein targeting to membraneGO:000661210.011
regulation of apoptotic processGO:0042981980.011
positive regulation of cyclin dependent protein serine threonine kinase activityGO:004573710.011
neural tube developmentGO:0021915620.011
heterocycle biosynthetic processGO:00181302150.011
directional locomotionGO:003305810.011
regulation of chromosome segregationGO:005198310.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
angiogenesisGO:00015251580.011
Zebrafish
negative regulation of cell migrationGO:0030336170.011
Mouse
eye morphogenesisGO:00485921440.011
outflow tract morphogenesisGO:000315110.011
positive regulation of jak stat cascadeGO:004642720.011
cell cycle g2 m phase transitionGO:004483940.011
midbrain hindbrain boundary developmentGO:0030917230.011
immune system processGO:00023762410.011
Zebrafish
thymus developmentGO:0048538100.011
Zebrafish
regulation of neuron differentiationGO:0045664560.011
Zebrafish Fly
negative regulation of nuclear divisionGO:005178430.011
cell morphogenesis involved in neuron differentiationGO:00486671630.010
Zebrafish Fly
alternative mrna splicing via spliceosomeGO:000038010.010
regulation of bone remodelingGO:004685020.010
regulation of neural precursor cell proliferationGO:200017730.010
peptidyl threonine modificationGO:001821010.010
negative regulation of biosynthetic processGO:0009890550.010
negative regulation of response to external stimulusGO:003210290.010
regulation of cell proliferationGO:0042127370.010
regulation of meiotic cell cycleGO:005144510.010
generation of neuronsGO:00486993850.010
Zebrafish Fly
calcium ion transport into cytosolGO:006040230.010
b cell activationGO:004211320.010
nephron tubule morphogenesisGO:007207810.010
microtubule cytoskeleton organizationGO:0000226330.010

sema6dl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.020
disease of anatomical entityDOID:700.018
organ system cancerDOID:005068600.014
cancerDOID:16200.014
cardiovascular system diseaseDOID:128700.012
acquired metabolic diseaseDOID:006015800.010
amyloidosisDOID:912000.010
disease of metabolismDOID:001466700.010