Danio rerio

10 known processes

usp25

ubiquitin specific protease 25

(Aliases: zgc:55791,wu:fp97a04,wu:fo67e06,wu:fi33c05)

usp25 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular macromolecule metabolic processGO:00442603910.344
Human
signal transductionGO:00071654550.237
regulation of metabolic processGO:00192223590.204
negative regulation of biological processGO:00485193040.175
protein metabolic processGO:00195381830.165
Human
modification dependent protein catabolic processGO:001994130.147
response to chemicalGO:00422213200.146
regulation of biosynthetic processGO:00098892500.144
cell surface receptor signaling pathwayGO:00071663250.135
negative regulation of cellular processGO:00485232830.117
positive regulation of catabolic processGO:000989640.116
phagocytosisGO:000690930.115
ubiquitin dependent protein catabolic processGO:000651130.109
regulation of signalingGO:00230512350.103
single organism metabolic processGO:00447102170.102
regulation of macromolecule metabolic processGO:00602553170.102
biosynthetic processGO:00090582940.095
modification dependent macromolecule catabolic processGO:004363230.092
positive regulation of cellular catabolic processGO:003133130.091
larval developmentGO:000216420.091
regulation of circadian rhythmGO:004275240.090
locomotor rhythmGO:004547530.089
cellular protein catabolic processGO:004425740.084
regulation of signal transductionGO:00099662250.082
nucleocytoplasmic transportGO:000691340.081
maintenance of locationGO:005123540.078
positive regulation of transportGO:005105020.077
establishment of protein localization to organelleGO:007259440.077
agingGO:000756820.077
regulation of cellular metabolic processGO:00313233200.076
cellular macromolecule biosynthetic processGO:00346452240.073
regulation of protein import into nucleusGO:004230620.070
single organism organelle organizationGO:19025891990.070
nuclear transportGO:005116940.068
nitrogen compound metabolic processGO:00068073190.065
regulation of cell communicationGO:00106462320.065
protein localization to nucleusGO:003450430.064
cytokinesisGO:000091030.064
negative regulation of cell communicationGO:0010648960.064
organic cyclic compound metabolic processGO:19013603010.063
phosphorus metabolic processGO:00067931090.061
golgi vesicle transportGO:004819330.061
protein dephosphorylationGO:000647030.060
meiotic nuclear divisionGO:000712640.059
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.058
proteolysis involved in cellular protein catabolic processGO:005160330.058
regulation of cellular macromolecule biosynthetic processGO:20001122220.057
regulation of response to stimulusGO:00485832690.057
meiotic cell cycle processGO:190304630.057
microtubule organizing center organizationGO:003102310.056
cellular biosynthetic processGO:00442492860.056
regulation of primary metabolic processGO:00800903110.056
cell deathGO:00082191210.056
programmed cell deathGO:00125011190.054
protein importGO:001703830.054
single organism nuclear importGO:190259330.054
cellular protein metabolic processGO:00442671290.054
Human
cellular component biogenesisGO:00440851780.054
regulation of cellular biosynthetic processGO:00313262450.053
positive regulation of biological processGO:00485182530.053
regulation of nucleobase containing compound metabolic processGO:00192192500.051
nucleic acid templated transcriptionGO:00976591810.050
nucleobase containing compound biosynthetic processGO:00346542050.049
single organism localizationGO:19025782250.048
lipid storageGO:001991510.048
organelle organizationGO:00069962270.048
adult behaviorGO:003053420.048
lateral inhibitionGO:004633110.048
negative regulation of cytoplasmic transportGO:190365020.047
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.047
cellular protein modification processGO:00064641000.047
Human
rna metabolic processGO:00160702190.045
neuron developmentGO:00486662620.045
cellular nitrogen compound biosynthetic processGO:00442712180.045
heterocycle metabolic processGO:00464832900.044
macromolecule biosynthetic processGO:00090592270.044
regulation of protein modification by small protein conjugation or removalGO:190332030.042
cell part morphogenesisGO:00329902460.042
cellular nitrogen compound metabolic processGO:00346412900.042
embryonic organ developmentGO:00485683810.042
stem cell proliferationGO:007208940.042
regulation of protein targetingGO:190353320.041
macromolecular complex subunit organizationGO:0043933740.041
gtp metabolic processGO:004603940.041
entrainment of circadian clockGO:000964920.041
tube morphogenesisGO:00352393490.040
cellular aromatic compound metabolic processGO:00067252950.040
cell projection organizationGO:00300302840.040
regulation of carbohydrate metabolic processGO:000610940.040
multi organism processGO:00517041340.040
protein import into nucleusGO:000660630.039
protein targeting to nucleusGO:004474430.039
regulation of rna metabolic processGO:00512522240.039
single organism transportGO:00447652060.039
regulation of multicellular organism growthGO:004001440.039
cellular response to chemical stimulusGO:00708871570.038
regulation of protein ubiquitinationGO:003139630.038
gtp catabolic processGO:000618420.038
transportGO:00068102200.038
nucleobase containing compound metabolic processGO:00061392740.038
organic substance biosynthetic processGO:19015762890.038
nucleic acid metabolic processGO:00903042440.038
multicellular organism growthGO:003526440.037
stem cell maintenanceGO:001982740.037
mitochondrion organizationGO:000700540.037
rna biosynthetic processGO:00327741810.037
macromolecule modificationGO:00434121110.037
Human
nuclear importGO:005117030.037
proteasomal protein catabolic processGO:001049820.037
positive regulation of cellular processGO:00485222010.037
regulation of macromolecule biosynthetic processGO:00105562250.036
regulation of protein transportGO:005122330.036
heterocycle biosynthetic processGO:00181302150.036
regulation of organelle assemblyGO:190211540.036
erk1 and erk2 cascadeGO:007037140.036
regulation of nucleic acid templated transcriptionGO:19035062130.036
embryo development ending in birth or egg hatchingGO:00097922710.036
amine metabolic processGO:000930820.036
digestive system developmentGO:00551232890.036
regulation of nitrogen compound metabolic processGO:00511712510.036
apoptotic processGO:00069151160.035
negative regulation of ras protein signal transductionGO:004658010.035
lamellipodium organizationGO:009758110.035
dna templated transcription elongationGO:000635430.034
negative regulation of signal transductionGO:0009968940.034
meiotic chromosome segregationGO:004513230.034
cellular carbohydrate metabolic processGO:004426240.034
phosphate containing compound metabolic processGO:00067961080.034
regulation of nucleocytoplasmic transportGO:004682220.033
cellular amine metabolic processGO:004410620.033
negative regulation of response to stimulusGO:00485851040.033
regulation of transcription dna templatedGO:00063552130.033
brain developmentGO:00074202930.032
regulation of protein catabolic processGO:004217610.032
response to external stimulusGO:00096052640.032
gene expressionGO:00104672520.032
regulation of nucleoside metabolic processGO:000911820.032
regulation of establishment of protein localizationGO:007020140.031
development of primary female sexual characteristicsGO:004654540.031
wnt signaling pathwayGO:0016055800.031
guanosine containing compound metabolic processGO:190106840.031
cell projection morphogenesisGO:00488582440.031
regulation of intracellular protein transportGO:003315730.031
negative regulation of protein phosphorylationGO:000193340.031
cellular response to organic substanceGO:00713101050.030
response to stressGO:00069502630.030
negative regulation of protein kinase activityGO:000646940.030
lamellipodium assemblyGO:003003210.030
neuron differentiationGO:00301823530.030
carbohydrate biosynthetic processGO:001605110.030
transcription dna templatedGO:00063511810.030
response to organic substanceGO:00100331530.030
extrinsic apoptotic signaling pathwayGO:009719130.030
regulation of protein polymerizationGO:003227120.030
response to topologically incorrect proteinGO:003596620.029
enzyme linked receptor protein signaling pathwayGO:00071671060.029
centrosome organizationGO:005129710.029
embryonic organ morphogenesisGO:00485622740.029
regulation of nucleotide catabolic processGO:003081120.028
regulation of gene expressionGO:00104682650.028
cellular response to extracellular stimulusGO:003166820.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.028
positive regulation of cellular component biogenesisGO:004408930.028
single organism membrane fusionGO:004480120.028
cellular component movementGO:00069283350.027
locomotionGO:00400113130.027
negative regulation of programmed cell deathGO:0043069580.027
organelle assemblyGO:00709251100.027
head developmentGO:00603223030.027
cell migrationGO:00164772370.027
positive regulation of cellular metabolic processGO:0031325940.027
regulation of protein complex assemblyGO:004325430.026
response to alkaloidGO:004327920.026
response to vitaminGO:003327330.026
central nervous system developmentGO:00074173870.026
negative regulation of tor signalingGO:003200720.026
cellular component disassemblyGO:002241110.026
blood vessel morphogenesisGO:00485142160.026
peptidyl lysine acetylationGO:001839420.026
regulation of neural precursor cell proliferationGO:200017730.026
organic cyclic compound biosynthetic processGO:19013622230.026
actin filament polymerizationGO:003004120.025
regulation of apoptotic processGO:0042981980.025
regulation of cell deathGO:00109411030.025
regulation of cellular amino acid metabolic processGO:000652100.025
regulation of stem cell proliferationGO:007209120.025
digestive tract morphogenesisGO:00485462310.025
negative regulation of kinase activityGO:003367340.025
negative regulation of mapk cascadeGO:004340940.025
regulation of cellular carbohydrate metabolic processGO:001067540.025
establishment of localizationGO:00512342440.025
protein polyubiquitinationGO:000020940.025
negative regulation of cellular metabolic processGO:0031324770.025
negative regulation of macromolecule metabolic processGO:0010605760.025
regulation of protein localization to nucleusGO:190018020.025
regulation of cytoplasmic transportGO:190364940.025
system processGO:00030081850.024
cellular component assemblyGO:00226071700.024
meiosis iGO:000712710.024
positive regulation of cell cycleGO:004578730.024
positive regulation of i kappab kinase nf kappab signalingGO:004312330.024
developmental programmed cell deathGO:001062340.024
establishment of synaptic vesicle localizationGO:009748010.024
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.024
immune system processGO:00023762410.024
cell cycle processGO:0022402530.024
organonitrogen compound metabolic processGO:1901564740.024
regulation of cellular amine metabolic processGO:003323800.023
negative regulation of nucleocytoplasmic transportGO:004682320.023
apoptotic process involved in developmentGO:190274220.023
i kappab kinase nf kappab signalingGO:000724940.023
protein polymerizationGO:005125840.023
energy reserve metabolic processGO:000611220.023
neurotransmitter transportGO:000683620.023
guanosine containing compound catabolic processGO:190106920.023
regulation of protein complex disassemblyGO:004324410.023
spindle assemblyGO:005122520.023
protein complex disassemblyGO:004324110.023
macromolecular complex disassemblyGO:003298410.022
regulation of purine nucleotide catabolic processGO:003312120.022
negative regulation of protein complex assemblyGO:003133310.022
regulation of bindingGO:005109830.022
negative regulation of signalingGO:0023057960.022
positive regulation of nucleobase containing compound metabolic processGO:0045935690.022
cellular amino acid metabolic processGO:000652070.022
vasculature developmentGO:00019442780.022
regulation of developmental processGO:00507932470.022
g1 s transition of mitotic cell cycleGO:000008210.022
hormone transportGO:000991420.022
mitotic dna integrity checkpointGO:004477440.022
camera type eye developmentGO:00430102220.022
cognitionGO:005089010.022
protein modification processGO:00362111000.022
Human
locomotory behaviorGO:0007626340.022
positive regulation of map kinase activityGO:004340630.022
post embryonic organ developmentGO:004856940.022
response to unfolded proteinGO:000698620.022
anterior posterior pattern specificationGO:00099521520.022
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.022
mitotic cell cycle processGO:1903047480.022
negative regulation of nitrogen compound metabolic processGO:0051172590.021
positive regulation of stress activated mapk cascadeGO:003287430.021
positive regulation of gtpase activityGO:004354710.021
axon developmentGO:00615641660.021
er to golgi vesicle mediated transportGO:000688810.021
regulation of multicellular organismal processGO:00512392770.021
organic acid metabolic processGO:0006082310.021
regulation of rna biosynthetic processGO:20011412130.021
positive regulation of notch signaling pathwayGO:004574730.021
vacuolar transportGO:000703420.021
positive regulation of metabolic processGO:00098931080.021
transcription elongation from rna polymerase ii promoterGO:000636830.021
regulation of i kappab kinase nf kappab signalingGO:004312240.021
sensory organ morphogenesisGO:00905962000.021
cellular response to external stimulusGO:007149620.021
response to light stimulusGO:0009416460.021
response to drugGO:004249330.021
neuroblast proliferationGO:000740520.021
generation of neuronsGO:00486993850.021
oxoacid metabolic processGO:0043436310.020
regulation of autophagyGO:001050630.020
regulation of cellular ketone metabolic processGO:001056570.020
peptide transportGO:001583310.020
sex determinationGO:000753010.020
morphogenesis of an epitheliumGO:00020093330.020
protein demethylationGO:000648220.020
chromosome organizationGO:0051276310.020
organic substance transportGO:0071702580.020
specification of symmetryGO:00097992040.020
ameboidal type cell migrationGO:00016671430.020
internal protein amino acid acetylationGO:000647520.020
negative regulation of map kinase activityGO:004340720.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
chordate embryonic developmentGO:00430092710.019
gastrulationGO:00073692080.019
autophagyGO:000691440.019
deathGO:00162651210.019
axonogenesisGO:00074091520.019
eye developmentGO:00016542770.019
cellular component morphogenesisGO:00329893360.019
cell motilityGO:00488702440.019
growthGO:00400071740.019
regulation of biological qualityGO:00650082630.019
synaptic vesicle transportGO:004848910.019
regionalizationGO:00030022740.019
protein complex localizationGO:003150310.019
regulation of dna templated transcription elongationGO:003278430.019
establishment of localization in cellGO:0051649770.019
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.019
positive regulation of nucleoside metabolic processGO:004597910.019
regulation of gtp catabolic processGO:003312420.019
regulation of filopodium assemblyGO:005148920.019
synaptic vesicle endocytosisGO:004848810.019
membrane invaginationGO:001032410.019
intracellular signal transductionGO:0035556850.018
female sex differentiationGO:004666040.018
digestive tract developmentGO:00485652650.018
hormone secretionGO:004687920.018
positive regulation of stem cell proliferationGO:200064810.018
regulation of erk1 and erk2 cascadeGO:007037240.018
protein acylationGO:004354330.018
cell cycle g1 s phase transitionGO:004484310.018
negative regulation of intracellular transportGO:003238730.018
protein acetylationGO:000647320.018
negative regulation of metabolic processGO:0009892860.018
positive regulation of gtp catabolic processGO:003312610.018
regulation of synaptic plasticityGO:004816710.018
internal peptidyl lysine acetylationGO:001839320.018
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.018
membrane fusionGO:006102520.018
sleepGO:003043110.018
circadian rhythmGO:0007623190.018
cell morphogenesis involved in neuron differentiationGO:00486671630.018
negative regulation of biosynthetic processGO:0009890550.018
cell morphogenesisGO:00009022890.018
regulation of synapse organizationGO:005080730.018
cellular response to starvationGO:000926710.018
regulation of cell shapeGO:000836010.018
synaptic vesicle recyclingGO:003646510.018
neurotransmitter secretionGO:000726920.018
cellular response to nutrient levelsGO:003166920.017
neuron projection developmentGO:00311751800.017
response to nutrientGO:000758430.017
primary neural tube formationGO:001402010.017
female gonad developmentGO:000858540.017
ribonucleoside monophosphate catabolic processGO:000915840.017
positive regulation of cell divisionGO:005178120.017
negative regulation of protein serine threonine kinase activityGO:007190120.017
glucose homeostasisGO:004259310.017
negative regulation of protein transportGO:005122430.017
activation of mapk activityGO:000018730.017
intracellular transportGO:0046907320.017
protein secretionGO:000930610.017
regulation of reproductive processGO:200024140.017
positive regulation of nucleotide catabolic processGO:003081310.017
regulation of dna replicationGO:000627530.017
homeostatic processGO:00425921420.016
negative regulation of defense responseGO:003134820.016
regulation of gtpase activityGO:004308720.016
blood vessel developmentGO:00015682460.016
regulation of protein depolymerizationGO:190187910.016
positive regulation of cell adhesionGO:004578510.016
positive regulation of purine nucleotide catabolic processGO:003312310.016
positive regulation of cellular amine metabolic processGO:003324000.016
positive regulation of canonical wnt signaling pathwayGO:009026340.016
negative regulation of cellular biosynthetic processGO:0031327550.016
localization of cellGO:00516742440.016
response to uvGO:000941130.016
regulation of tube sizeGO:003515020.016
epithelial tube morphogenesisGO:00605621480.016
insulin like growth factor receptor signaling pathwayGO:004800940.016
somatic muscle developmentGO:000752540.016
endosomal transportGO:001619720.016
carboxylic acid metabolic processGO:0019752220.016
organelle fusionGO:004828430.016
neuron projection morphogenesisGO:00488121610.016
phagocytosis engulfmentGO:000691110.016
regulation of localizationGO:00328791040.016
synaptic vesicle localizationGO:009747910.016
cellular response to topologically incorrect proteinGO:003596720.016
regulation of intracellular signal transductionGO:1902531570.016
small gtpase mediated signal transductionGO:000726480.016
regulation of cellular protein catabolic processGO:190336210.016
cell cycleGO:0007049930.015
spermatid developmentGO:000728620.015
er nucleus signaling pathwayGO:000698420.015
regulation of cytokine productionGO:000181730.015
g2 dna damage checkpointGO:003157230.015
behaviorGO:0007610740.015
regulation of jun kinase activityGO:004350630.015
endosome organizationGO:000703220.015
carbohydrate homeostasisGO:003350010.015
dorsal ventral pattern formationGO:00099531250.015
regulation of response to nutrient levelsGO:003210710.015
macroautophagyGO:001623610.015
post golgi vesicle mediated transportGO:000689210.015
cellular ketone metabolic processGO:0042180110.015
mitotic cell cycleGO:0000278640.015
cellular response to endogenous stimulusGO:0071495680.015
regulation of cellular protein metabolic processGO:0032268520.015
mitotic nuclear divisionGO:0007067180.015
regulation of blood vessel sizeGO:005088020.014
cellular response to stressGO:0033554620.014
actin polymerization or depolymerizationGO:000815420.014
camera type eye morphogenesisGO:00485931080.014
spermatid differentiationGO:004851520.014
regulation of protein metabolic processGO:0051246560.014
histone modificationGO:0016570200.014
regulation of wound healingGO:006104120.014
neuron neuron synaptic transmissionGO:000727010.014
angiogenesisGO:00015251580.014
nuclear exportGO:005116810.014
response to glucoseGO:000974930.014
centrosome cycleGO:000709810.014
regulation of cell developmentGO:00602841000.014
regulation of molecular functionGO:0065009700.014
carbohydrate derivative metabolic processGO:1901135610.014
protein homooligomerizationGO:005126030.014
positive regulation of macromolecule biosynthetic processGO:0010557590.014
small molecule metabolic processGO:0044281770.014
regulation of cell projection assemblyGO:006049140.014
regulation of cellular component sizeGO:0032535300.014
negative regulation of gene expressionGO:0010629650.014
positive regulation of cell communicationGO:0010647560.014
endoplasmic reticulum unfolded protein responseGO:003096820.014
determination of bilateral symmetryGO:00098552040.014
tube closureGO:006060610.013
negative regulation of intracellular signal transductionGO:1902532220.013
positive regulation of macromolecule metabolic processGO:0010604930.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
negative regulation of protein localization to nucleusGO:190018120.013
chromatin organizationGO:0006325220.013
response to hydrogen peroxideGO:004254230.013
cellular response to unfolded proteinGO:003462020.013
regulation of protein bindingGO:004339330.013
cell morphogenesis involved in differentiationGO:00009041950.013
regulation of stem cell differentiationGO:200073640.013
cellular localizationGO:0051641970.013
covalent chromatin modificationGO:0016569200.013
female meiotic divisionGO:000714320.013
response to endogenous stimulusGO:0009719830.013
positive regulation of protein complex assemblyGO:003133420.013
dicarboxylic acid transportGO:000683510.013
stem cell divisionGO:001714510.013
regulation of carbohydrate biosynthetic processGO:004325510.013
aromatic compound biosynthetic processGO:00194382170.013
germ line stem cell maintenanceGO:003071820.013
regulation of organ growthGO:004662030.013
cell agingGO:000756920.013
cartilage developmentGO:0051216960.013
regulation of cell activationGO:005086510.013
positive regulation of jnk cascadeGO:004633030.013
peptidyl serine phosphorylationGO:001810510.013
glial cell proliferationGO:001400940.013
regulation of programmed cell deathGO:00430671010.013
cell substrate adhesionGO:003158940.013
regulation of meiotic cell cycleGO:005144510.013
pyruvate metabolic processGO:000609010.013
exocytosisGO:000688710.013
canonical wnt signaling pathwayGO:0060070480.013
negative regulation of cytokine productionGO:000181810.013
regulation of transcription from rna polymerase ii promoterGO:00063571140.013
negative regulation of intracellular protein transportGO:009031730.013
regulation of synapse assemblyGO:005196330.013
skeletal system morphogenesisGO:00487051020.013
regulation of response to cytokine stimulusGO:006075930.012
regulation of catalytic activityGO:0050790550.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
determination of heart left right asymmetryGO:00613711170.012
regulation of phGO:000688530.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
sensory organ developmentGO:00074233930.012
signal transduction in absence of ligandGO:003803410.012
odontogenesis of dentin containing toothGO:004247510.012
androgen metabolic processGO:000820920.012
cellular response to biotic stimulusGO:007121630.012
nuclear divisionGO:0000280230.012
sexual reproductionGO:0019953360.012
protein depolymerizationGO:005126110.012
lipid homeostasisGO:005508830.012
sequestering of metal ionGO:005123830.012
cellular protein complex disassemblyGO:004362410.012
positive regulation of transcription dna templatedGO:0045893570.012
centrosome duplicationGO:005129810.012
heart loopingGO:0001947940.012
regulation of wnt signaling pathwayGO:0030111530.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
alcohol biosynthetic processGO:004616520.012
protein complex biogenesisGO:0070271300.012
cellular response to radiationGO:007147840.012
regulation of cellular component organizationGO:0051128860.012
heart developmentGO:00075073130.012
circadian sleep wake cycle sleepGO:005080210.012
regulation of dna recombinationGO:000001820.012
regulation of cellular response to growth factor stimulusGO:0090287350.012
organic substance catabolic processGO:1901575280.012
cartilage condensationGO:000150230.012
golgi organizationGO:000703010.012
single organism biosynthetic processGO:0044711710.012
response to woundingGO:00096111160.012
cellular protein localizationGO:0034613200.012
negative regulation of catabolic processGO:000989530.012
regulation of mitotic cell cycleGO:0007346250.012
negative regulation of apoptotic processGO:0043066550.012
mitotic g2 m transition checkpointGO:004481830.012
endocrine hormone secretionGO:006098620.011
smoothened signaling pathwayGO:0007224300.011
atp catabolic processGO:000620040.011
synaptic growth at neuromuscular junctionGO:005112420.011
positive regulation of cytoskeleton organizationGO:005149530.011

usp25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
organ system cancerDOID:005068600.017
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
nervous system diseaseDOID:86300.016
musculoskeletal system diseaseDOID:1700.013