Danio rerio

0 known processes

pmp22b

peripheral myelin protein 22b

(Aliases: id:ibd2630,zgc:136919,wu:fb81f09,MGC136919)

pmp22b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of biological processGO:00485193040.254
immune system processGO:00023762410.231
locomotionGO:00400113130.137
regulation of cell communicationGO:00106462320.131
larval developmentGO:000216420.117
heterocycle metabolic processGO:00464832900.112
connective tissue developmentGO:0061448990.111
macromolecule biosynthetic processGO:00090592270.109
cellular macromolecule biosynthetic processGO:00346452240.106
regulation of epithelial cell proliferationGO:005067830.102
skeletal system developmentGO:00015011810.102
ribonucleoside monophosphate catabolic processGO:000915840.100
regulation of cell differentiationGO:00455951420.091
gene expressionGO:00104672520.089
regulation of metabolic processGO:00192223590.088
cellular biosynthetic processGO:00442492860.087
regulation of response to stimulusGO:00485832690.085
single organism localizationGO:19025782250.084
regulation of cell projection assemblyGO:006049140.079
regulation of nitrogen compound metabolic processGO:00511712510.078
regulation of signalingGO:00230512350.077
regulation of stem cell differentiationGO:200073640.075
negative regulation of cellular processGO:00485232830.074
agingGO:000756820.073
cellular macromolecule metabolic processGO:00442603910.070
response to carbohydrateGO:000974330.068
mesenchyme developmentGO:00604851270.068
transcription dna templatedGO:00063511810.068
signal transductionGO:00071654550.066
organic cyclic compound metabolic processGO:19013603010.065
cellular aromatic compound metabolic processGO:00067252950.065
cellular response to nutrient levelsGO:003166920.065
hemopoiesisGO:00300971830.063
embryonic organ developmentGO:00485683810.063
transportGO:00068102200.063
regulation of signal transductionGO:00099662250.061
regulation of cellular metabolic processGO:00313233200.061
single organism transportGO:00447652060.060
cellular nitrogen compound metabolic processGO:00346412900.059
skeletal system morphogenesisGO:00487051020.057
regulation of gene expressionGO:00104682650.056
endosomal transportGO:001619720.056
embryo development ending in birth or egg hatchingGO:00097922710.056
stem cell differentiationGO:00488631170.056
single organism metabolic processGO:00447102170.055
rna metabolic processGO:00160702190.055
maintenance of locationGO:005123540.053
regulation of primary metabolic processGO:00800903110.052
regulation of cellular macromolecule biosynthetic processGO:20001122220.052
stem cell maintenanceGO:001982740.052
cellular response to external stimulusGO:007149620.052
localization of cellGO:00516742440.051
cellular response to extracellular stimulusGO:003166820.051
muscle tissue developmentGO:00605371100.051
organic substance biosynthetic processGO:19015762890.050
extrinsic apoptotic signaling pathwayGO:009719130.050
notochord developmentGO:0030903540.050
regulation of rna metabolic processGO:00512522240.049
cartilage developmentGO:0051216960.048
deathGO:00162651210.048
Human
regulation of epithelial to mesenchymal transitionGO:001071730.048
nucleic acid metabolic processGO:00903042440.047
regulation of endothelial cell proliferationGO:000193610.047
organic cyclic compound biosynthetic processGO:19013622230.046
regulation of macromolecule metabolic processGO:00602553170.046
negative regulation of signalingGO:0023057960.044
cell deathGO:00082191210.044
Human
meiotic nuclear divisionGO:000712640.043
cellular carbohydrate metabolic processGO:004426240.043
positive regulation of biological processGO:00485182530.042
cell substrate adhesionGO:003158940.042
purine ribonucleoside monophosphate catabolic processGO:000916940.040
positive regulation of cell communicationGO:0010647560.040
regulation of biosynthetic processGO:00098892500.039
response to hexoseGO:000974630.039
hematopoietic or lymphoid organ developmentGO:00485341910.038
protein polymerizationGO:005125840.038
calcium ion transport into cytosolGO:006040230.038
cell surface receptor signaling pathwayGO:00071663250.037
heart morphogenesisGO:00030071560.036
collagen biosynthetic processGO:003296420.036
head developmentGO:00603223030.035
biosynthetic processGO:00090582940.035
nitrogen compound metabolic processGO:00068073190.035
hepaticobiliary system developmentGO:0061008980.035
nucleoside monophosphate catabolic processGO:000912540.035
brain developmentGO:00074202930.034
atp catabolic processGO:000620040.034
aromatic compound biosynthetic processGO:00194382170.034
cellular nitrogen compound biosynthetic processGO:00442712180.033
purine nucleoside monophosphate catabolic processGO:000912840.033
odontogenesis of dentin containing toothGO:004247510.033
ion transmembrane transportGO:0034220910.032
negative regulation of cell communicationGO:0010648960.032
wound healingGO:0042060900.032
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.032
central nervous system developmentGO:00074173870.032
phagocytosisGO:000690930.032
regulation of biological qualityGO:00650082630.032
Zebrafish
regulation of developmental processGO:00507932470.032
striated muscle tissue developmentGO:00147061100.032
regulation of cellular biosynthetic processGO:00313262450.032
regulation of multicellular organismal processGO:00512392770.032
Zebrafish
regulation of transcription dna templatedGO:00063552130.031
negative regulation of response to stimulusGO:00485851040.031
establishment of protein localization to organelleGO:007259440.031
system processGO:00030081850.031
Zebrafish
regulation of nucleobase containing compound metabolic processGO:00192192500.031
positive regulation of gtp catabolic processGO:003312610.030
determination of left right symmetryGO:00073681790.030
growthGO:00400071740.030
positive regulation of cell cycleGO:004578730.030
response to chemicalGO:00422213200.030
heterocycle biosynthetic processGO:00181302150.030
response to drugGO:004249330.029
cell migrationGO:00164772370.029
regionalizationGO:00030022740.029
response to monosaccharideGO:003428430.029
fin regenerationGO:0031101510.028
immune system developmentGO:00025201910.028
carbohydrate biosynthetic processGO:001605110.028
intracellular signal transductionGO:0035556850.028
cell motilityGO:00488702440.028
blood vessel developmentGO:00015682460.028
regulation of multicellular organismal developmentGO:20000262230.027
positive regulation of signal transductionGO:0009967560.027
response to nutrientGO:000758430.027
regulation of cell substrate adhesionGO:001081010.027
chordate embryonic developmentGO:00430092710.027
cellular component movementGO:00069283350.027
blood vessel morphogenesisGO:00485142160.027
organelle organizationGO:00069962270.027
skeletal muscle organ developmentGO:0060538780.026
regulation of anatomical structure morphogenesisGO:00226031300.026
regulation of cell developmentGO:00602841000.026
establishment of localizationGO:00512342440.026
regulation of intracellular signal transductionGO:1902531570.026
regulation of mrna splicing via spliceosomeGO:004802430.026
positive regulation of purine nucleotide catabolic processGO:003312310.026
gtp metabolic processGO:004603940.026
regulation of cellular component organizationGO:0051128860.026
positive regulation of catabolic processGO:000989640.025
response to amino acidGO:004320020.025
macromolecule localizationGO:0033036540.025
multicellular organism growthGO:003526440.024
cell morphogenesisGO:00009022890.024
regulation of organ growthGO:004662030.024
regulation of multicellular organism growthGO:004001440.024
regulation of erk1 and erk2 cascadeGO:007037240.024
protein localization to plasma membraneGO:007265910.024
transcription from rna polymerase ii promoterGO:0006366800.023
multicellular organismal metabolic processGO:004423620.023
single organism biosynthetic processGO:0044711710.023
cellular response to starvationGO:000926710.023
stem cell proliferationGO:007208940.023
complement activationGO:000695630.023
regulation of nucleic acid templated transcriptionGO:19035062130.023
regulation of cell matrix adhesionGO:000195210.023
cellular component disassemblyGO:002241110.023
protein importGO:001703830.023
negative regulation of signal transductionGO:0009968940.023
muscle structure developmentGO:00610611960.023
organonitrogen compound metabolic processGO:1901564740.023
germ line stem cell maintenanceGO:003071820.022
cellular amine metabolic processGO:004410620.022
negative regulation of developmental processGO:0051093650.022
regulation of cell morphogenesisGO:0022604420.022
nucleobase containing compound biosynthetic processGO:00346542050.022
nucleotide metabolic processGO:0009117280.022
regulation of blood pressureGO:000821710.021
Zebrafish
specification of symmetryGO:00097992040.021
embryonic organ morphogenesisGO:00485622740.021
regulation of striated muscle contractionGO:000694220.021
nucleocytoplasmic transportGO:000691340.021
pigmentationGO:0043473850.021
regulation of nucleoside metabolic processGO:000911820.021
stem cell developmentGO:0048864820.021
carbohydrate derivative metabolic processGO:1901135610.021
positive regulation of erk1 and erk2 cascadeGO:007037420.021
response to external stimulusGO:00096052640.021
purine ribonucleotide metabolic processGO:0009150270.021
female gonad developmentGO:000858540.020
golgi vesicle transportGO:004819330.020
positive regulation of nitrogen compound metabolic processGO:0051173690.020
response to glucoseGO:000974930.020
negative regulation of intracellular signal transductionGO:1902532220.020
response to inorganic substanceGO:0010035380.020
regulation of cell deathGO:00109411030.020
tissue regenerationGO:0042246740.020
cell cycle arrestGO:000705010.020
positive regulation of canonical wnt signaling pathwayGO:009026340.020
negative regulation of epithelial cell proliferationGO:005068010.020
positive regulation of translationGO:004572710.020
nuclear transportGO:005116940.019
response to vitaminGO:003327330.019
negative regulation of cytokine productionGO:000181810.019
determination of bilateral symmetryGO:00098552040.019
protein complex disassemblyGO:004324110.019
multicellular organismal macromolecule metabolic processGO:004425920.019
spermatid developmentGO:000728620.019
intracellular transportGO:0046907320.019
regulation of alternative mrna splicing via spliceosomeGO:000038110.019
positive regulation of cellular catabolic processGO:003133130.019
positive regulation of response to stimulusGO:0048584800.019
female sex differentiationGO:004666040.019
cellular protein metabolic processGO:00442671290.018
protein secretionGO:000930610.018
cell matrix adhesionGO:000716040.018
regulation of macromolecule biosynthetic processGO:00105562250.018
regulation of protein catabolic processGO:004217610.018
mesenchymal cell developmentGO:0014031780.018
cellular protein modification processGO:00064641000.018
leukocyte proliferationGO:007066110.018
septum transversum developmentGO:000334340.018
myotube cell developmentGO:0014904350.018
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.018
Zebrafish
positive regulation of nucleoside metabolic processGO:004597910.017
protein localization to nucleusGO:003450430.017
regulation of neurogenesisGO:0050767870.017
regulation of rna biosynthetic processGO:20011412130.017
phosphorus metabolic processGO:00067931090.017
regulation of protein complex assemblyGO:004325430.017
positive regulation of nucleotide catabolic processGO:003081310.017
transmembrane transportGO:00550851200.017
rna biosynthetic processGO:00327741810.017
protein import into nucleusGO:000660630.017
wnt signaling pathwayGO:0016055800.017
positive regulation of cellular processGO:00485222010.017
transmission of nerve impulseGO:0019226190.017
cytoskeleton organizationGO:0007010960.017
positive regulation of macromolecule biosynthetic processGO:0010557590.017
apoptotic processGO:00069151160.017
negative regulation of epithelial cell migrationGO:001063310.017
amine metabolic processGO:000930820.017
negative regulation of stem cell differentiationGO:200073720.017
cellular response to chemical stimulusGO:00708871570.017
negative regulation of mitosisGO:004583930.017
vasculature developmentGO:00019442780.017
immune responseGO:0006955280.016
protein localization to membraneGO:007265790.016
cell projection organizationGO:00300302840.016
Human
macromolecular complex disassemblyGO:003298410.016
lipid storageGO:001991510.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
liver developmentGO:0001889960.016
sensory organ developmentGO:00074233930.016
heart developmentGO:00075073130.016
tissue remodelingGO:004877140.016
regulation of blood vessel sizeGO:005088020.016
developmental growthGO:00485891660.016
regulation of cellular amine metabolic processGO:003323800.016
cytosolic calcium ion transportGO:006040130.016
dorsal ventral pattern formationGO:00099531250.016
cartilage morphogenesisGO:0060536130.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
embryonic heart tube morphogenesisGO:00031431080.016
regulation of nucleotide catabolic processGO:003081120.016
angiogenesisGO:00015251580.016
regulation of gtp catabolic processGO:003312420.016
regulation of protein complex disassemblyGO:004324410.016
erk1 and erk2 cascadeGO:007037140.016
regulation of cytokine productionGO:000181730.016
regulation of reproductive processGO:200024140.015
nuclear importGO:005117030.015
response to woundingGO:00096111160.015
regulation of apoptotic processGO:0042981980.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
anterior posterior pattern specificationGO:00099521520.015
single organism nuclear importGO:190259330.015
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.015
actin filament based processGO:0030029640.015
regulation of wnt signaling pathwayGO:0030111530.015
striated muscle cell differentiationGO:00511461290.015
regulation of ion transmembrane transporter activityGO:003241220.015
regulation of response to biotic stimulusGO:000283120.014
cardiac atrium developmentGO:000323040.014
cellular localizationGO:0051641970.014
response to corticosteroidGO:003196010.014
multi organism processGO:00517041340.014
canonical wnt signaling pathwayGO:0060070480.014
muscle fiber developmentGO:0048747520.014
phagocytosis engulfmentGO:000691110.014
cellular component morphogenesisGO:00329893360.014
Mouse
heart loopingGO:0001947940.014
determination of heart left right asymmetryGO:00613711170.014
protein metabolic processGO:00195381830.014
alternative mrna splicing via spliceosomeGO:000038010.014
segmentationGO:0035282970.014
homeostatic processGO:00425921420.014
regulation of protein ubiquitinationGO:003139630.014
homeostasis of number of cellsGO:0048872620.014
negative regulation of sequestering of calcium ionGO:005128340.014
positive regulation of cell activationGO:005086710.014
regulation of purine nucleotide catabolic processGO:003312120.014
macromolecular complex assemblyGO:0065003350.014
regulation of bindingGO:005109830.014
convergent extensionGO:00600261180.014
nucleic acid templated transcriptionGO:00976591810.014
compound eye developmentGO:004874920.014
positive regulation of gtpase activityGO:004354710.014
cellular response to retinoic acidGO:007130010.014
appendage morphogenesisGO:0035107560.014
neural crest cell differentiationGO:0014033720.013
regulation of cell activationGO:005086510.013
regulation of establishment of protein localizationGO:007020140.013
peptide transportGO:001583310.013
circulatory system processGO:0003013870.013
Zebrafish
small molecule metabolic processGO:0044281770.013
regenerationGO:0031099910.013
tube morphogenesisGO:00352393490.013
response to xenobiotic stimulusGO:0009410450.013
spermatid differentiationGO:004851520.013
renal system process involved in regulation of blood volumeGO:000197710.013
Zebrafish
somitogenesisGO:0001756870.013
multicellular organismal signalingGO:0035637220.013
programmed cell deathGO:00125011190.013
positive regulation of wound healingGO:009030310.013
muscle cell developmentGO:00550011150.013
gtp catabolic processGO:000618420.013
negative regulation of dna metabolic processGO:005105340.013
phosphorylationGO:0016310690.012
proteasomal protein catabolic processGO:001049820.012
regulation of cytoplasmic transportGO:190364940.012
negative regulation of map kinase activityGO:004340720.012
secondary metabolic processGO:001974830.012
oocyte maturationGO:000155640.012
meiotic chromosome segregationGO:004513230.012
outflow tract morphogenesisGO:000315110.012
regulation of cellular ketone metabolic processGO:001056570.012
lamellipodium assemblyGO:003003210.012
protein modification processGO:00362111000.012
regulation of reactive oxygen species metabolic processGO:200037720.012
regulation of molecular functionGO:0065009700.012
cellular response to endogenous stimulusGO:0071495680.012
lymphocyte proliferationGO:004665110.012
cellular response to fibroblast growth factor stimulusGO:0044344220.012
embryonic hemopoiesisGO:0035162530.012
regulation of cellular amino acid metabolic processGO:000652100.012
lamellipodium organizationGO:009758110.012
nucleobase containing compound metabolic processGO:00061392740.012
regulation of synaptic plasticityGO:004816710.012
cell projection morphogenesisGO:00488582440.012
positive regulation of cellular component biogenesisGO:004408930.012
growth plate cartilage developmentGO:000341720.012
regulation of cell migrationGO:0030334400.012
cellular response to growth factor stimulusGO:0071363390.012
single organism intracellular transportGO:1902582250.012
ribonucleotide metabolic processGO:0009259270.012
regulation of wound healingGO:006104120.012
single organism organelle organizationGO:19025891990.012
negative regulation of protein complex assemblyGO:003133310.012
activation of mapk activityGO:000018730.012
regulation of systemic arterial blood pressureGO:000307310.012
Zebrafish
cellular response to organic substanceGO:00713101050.012
cellular component biogenesisGO:00440851780.012
Human
neural crest cell developmentGO:0014032620.012
positive regulation of biosynthetic processGO:0009891680.012
sprouting angiogenesisGO:0002040530.012
cellular protein catabolic processGO:004425740.012
negative regulation of nuclear divisionGO:005178430.012
pancreas developmentGO:0031016840.012
negative regulation of mapk cascadeGO:004340940.012
regulation of muscle contractionGO:000693730.012
negative regulation of protein phosphorylationGO:000193340.012
cellular amino acid metabolic processGO:000652070.011
cell adhesion mediated by integrinGO:003362710.011
positive regulation of gene expressionGO:0010628710.011
protein depolymerizationGO:005126110.011
cell killingGO:000190620.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
catabolic processGO:0009056320.011
purine nucleotide metabolic processGO:0006163270.011
positive regulation of secretionGO:005104710.011
positive regulation of muscle cell differentiationGO:005114910.011
peptidyl lysine acetylationGO:001839420.011
organic substance transportGO:0071702580.011
cellular protein complex disassemblyGO:004362410.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
membrane invaginationGO:001032410.011
regulation of cell fate commitmentGO:0010453220.011
trabecula morphogenesisGO:006138320.011
somatic muscle developmentGO:000752540.011
negative regulation of mesodermal cell fate specificationGO:004266230.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.011
synaptic transmission cholinergicGO:000727140.011
astrocyte differentiationGO:004870810.011
zymogen activationGO:003163830.011
positive regulation of metabolic processGO:00098931080.011
post golgi vesicle mediated transportGO:000689210.011
nucleobase containing small molecule metabolic processGO:0055086320.011
nuclear exportGO:005116810.011
embryonic heart tube developmentGO:00350501330.011
bmp signaling pathwayGO:0030509520.011
cartilage condensationGO:000150230.011
positive regulation of macromolecule metabolic processGO:0010604930.011
regulation of calcium ion transportGO:005192420.011
gland developmentGO:00487321430.011
positive regulation of cell adhesionGO:004578510.011
regulation of cell shapeGO:000836010.011
ameboidal type cell migrationGO:00016671430.011
trabecula formationGO:006034320.011
lipid digestionGO:004424130.011
centrosome organizationGO:005129710.011
chondrocyte developmentGO:000206340.011
erythrocyte homeostasisGO:0034101550.011
phosphate containing compound metabolic processGO:00067961080.010
proepicardium developmentGO:000334240.010
establishment of protein localization to plasma membraneGO:009000210.010
guanosine containing compound metabolic processGO:190106840.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
mitochondrion organizationGO:000700540.010
regulation of tube sizeGO:003515020.010
negative regulation of cell deathGO:0060548600.010
guanosine containing compound catabolic processGO:190106920.010
negative regulation of secretionGO:005104820.010
positive regulation of cellular amine metabolic processGO:003324000.010
epithelial cell migrationGO:0010631250.010
regulation of transmembrane transporter activityGO:002289820.010
positive regulation of signalingGO:0023056560.010
negative regulation of cellular biosynthetic processGO:0031327550.010
embryonic skeletal system developmentGO:0048706970.010
tissue migrationGO:0090130370.010
regulation of transcription from rna polymerase ii promoterGO:00063571140.010
organic substance catabolic processGO:1901575280.010
protein dephosphorylationGO:000647030.010
fatty acid transportGO:001590810.010
carboxylic acid metabolic processGO:0019752220.010
cellular ketone metabolic processGO:0042180110.010
cellular component assemblyGO:00226071700.010
Human
positive regulation of protein kinase b signalingGO:005189710.010
oxoacid metabolic processGO:0043436310.010
mononuclear cell proliferationGO:003294310.010
regulation of phGO:000688530.010
modification dependent macromolecule catabolic processGO:004363230.010
regulation of gtpase activityGO:004308720.010
forebrain developmentGO:0030900960.010
glucose homeostasisGO:004259310.010
regulation of cell morphogenesis involved in differentiationGO:0010769380.010
hatching gland developmentGO:004878530.010
purine containing compound metabolic processGO:0072521290.010
fin developmentGO:0033333770.010
regulation of ras gtpase activityGO:003231820.010
negative regulation of rna splicingGO:003311910.010

pmp22b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.096
Human
musculoskeletal system diseaseDOID:1700.040
connective tissue diseaseDOID:6500.027
bone diseaseDOID:008000100.027
neuropathyDOID:87000.017
Human
charcot marie tooth disease type 4DOID:005054100.017
Human
charcot marie tooth diseaseDOID:1059500.017
Human
neuromuscular diseaseDOID:44000.017
Human
nervous system diseaseDOID:86300.017
Human
cardiovascular system diseaseDOID:128700.014
bone development diseaseDOID:008000600.012
disease of cellular proliferationDOID:1456600.012
heart diseaseDOID:11400.012
myopathyDOID:42300.011
muscular diseaseDOID:008000000.011
intrinsic cardiomyopathyDOID:006003600.011
muscle tissue diseaseDOID:6600.011
cardiomyopathyDOID:005070000.011
osteochondrodysplasiaDOID:225600.011