IMP: Integrative Multi-species Prediction

Danio rerio

0 known processes

cyc1

cytochrome c-1

(Aliases: sr:nyz104,zgc:123089,MGC123089,im:6911272,fb80h03,wu:fb80h03)

ZFIN: ZDB-GENE-031105-2
Ensembl: ENSDARG00000038075
Entrez: 564379
UniProtKB: Q3B7R0

Process Predictions
Disease Predictions

cyc1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular respiration	GO:0045333	3	0.744	Yeast
coenzyme biosynthetic process	GO:0009108	2	0.455
acetyl coa metabolic process	GO:0006084	1	0.370
oxidative phosphorylation	GO:0006119	1	0.343	Yeast
embryo development ending in birth or egg hatching	GO:0009792	271	0.261	Worm
small molecule metabolic process	GO:0044281	77	0.236	Yeast Worm
mitochondrion organization	GO:0007005	4	0.235
aging	GO:0007568	2	0.225	Worm
larval development	GO:0002164	2	0.208	Worm
oxidation reduction process	GO:0055114	41	0.205	Yeast
thioester biosynthetic process	GO:0035384	1	0.187
regulation of metabolic process	GO:0019222	359	0.148
cellular component movement	GO:0006928	335	0.128
mitochondrion morphogenesis	GO:0070584	2	0.126
regulation of neural precursor cell proliferation	GO:2000177	3	0.109
multi organism process	GO:0051704	134	0.106	Worm
multicellular organism growth	GO:0035264	4	0.102
stem cell proliferation	GO:0072089	4	0.101
acyl coa biosynthetic process	GO:0071616	1	0.091
respiratory electron transport chain	GO:0022904	2	0.090	Yeast
regulation of stem cell proliferation	GO:0072091	2	0.089
electron transport chain	GO:0022900	2	0.071	Yeast
thioester metabolic process	GO:0035383	1	0.063
developmental growth	GO:0048589	166	0.062
system process	GO:0003008	185	0.062
sulfur compound biosynthetic process	GO:0044272	9	0.059
single organism localization	GO:1902578	225	0.057	Worm
cell motility	GO:0048870	244	0.057
negative regulation of biological process	GO:0048519	304	0.054
pyruvate metabolic process	GO:0006090	1	0.052
oxoacid metabolic process	GO:0043436	31	0.052
mitochondrial atp synthesis coupled electron transport	GO:0042775	1	0.052	Yeast
reproduction	GO:0000003	40	0.050	Worm
cellular response to topologically incorrect protein	GO:0035967	2	0.050
localization of cell	GO:0051674	244	0.050
cellular process involved in reproduction in multicellular organism	GO:0022412	28	0.048
mitochondrial transport	GO:0006839	2	0.048	Worm
gene silencing by rna	GO:0031047	4	0.047
regulation of multicellular organism growth	GO:0040014	4	0.046
negative regulation of gene expression	GO:0010629	65	0.046
embryonic organ development	GO:0048568	381	0.046
signal transduction	GO:0007165	455	0.045
energy derivation by oxidation of organic compounds	GO:0015980	5	0.044	Yeast
endoplasmic reticulum unfolded protein response	GO:0030968	2	0.043
carboxylic acid metabolic process	GO:0019752	22	0.041
cell migration	GO:0016477	237	0.040
organic acid metabolic process	GO:0006082	31	0.040
cellular response to unfolded protein	GO:0034620	2	0.040
single organism metabolic process	GO:0044710	217	0.038	Yeast Worm
atp synthesis coupled electron transport	GO:0042773	1	0.038	Yeast
generation of precursor metabolites and energy	GO:0006091	5	0.037	Yeast
cofactor biosynthetic process	GO:0051188	10	0.037
sexual reproduction	GO:0019953	36	0.036
growth	GO:0040007	174	0.036
regulation of developmental process	GO:0050793	247	0.036
spermatid development	GO:0007286	2	0.034
developmental process involved in reproduction	GO:0003006	27	0.033	Worm
response to external stimulus	GO:0009605	264	0.031
establishment of localization	GO:0051234	244	0.030	Worm
nucleobase containing compound metabolic process	GO:0006139	274	0.030	Yeast Worm
regulation of biological quality	GO:0065008	263	0.029
establishment of protein localization to organelle	GO:0072594	4	0.029
transport	GO:0006810	220	0.027	Worm
neuroblast proliferation	GO:0007405	2	0.027
regulation of gene expression	GO:0010468	265	0.026
response to chemical	GO:0042221	320	0.026
heterocycle metabolic process	GO:0046483	290	0.026	Yeast Worm
spermatid differentiation	GO:0048515	2	0.025
negative regulation of cellular process	GO:0048523	283	0.025
carboxylic acid catabolic process	GO:0046395	3	0.025
germ cell development	GO:0007281	22	0.024
response to biotic stimulus	GO:0009607	97	0.024
er nucleus signaling pathway	GO:0006984	2	0.024
negative regulation of neural precursor cell proliferation	GO:2000178	1	0.024
acyl coa metabolic process	GO:0006637	1	0.024
blood vessel development	GO:0001568	246	0.023
blood vessel morphogenesis	GO:0048514	216	0.023
posttranscriptional gene silencing	GO:0016441	3	0.023
morphogenesis of an epithelium	GO:0002009	333	0.022
response to organic substance	GO:0010033	153	0.022
regulation of epithelial cell proliferation	GO:0050678	3	0.022
response to unfolded protein	GO:0006986	2	0.022
immune system development	GO:0002520	191	0.022
gene silencing	GO:0016458	4	0.022
posttranscriptional gene silencing by rna	GO:0035194	3	0.021
single organism reproductive process	GO:0044702	40	0.021	Worm
gene expression	GO:0010467	252	0.021
transmembrane transport	GO:0055085	120	0.021	Worm
regulation of nucleoside metabolic process	GO:0009118	2	0.021
coenzyme metabolic process	GO:0006732	5	0.020
generation of neurons	GO:0048699	385	0.020
specification of organ axis polarity	GO:0010084	2	0.020
mitochondrial electron transport nadh to ubiquinone	GO:0006120	1	0.019
locomotion	GO:0040011	313	0.019
vasculature development	GO:0001944	278	0.019
regulation of multicellular organismal process	GO:0051239	277	0.018
organic substance biosynthetic process	GO:1901576	289	0.018	Worm
dicarboxylic acid metabolic process	GO:0043648	1	0.018
negative regulation of metabolic process	GO:0009892	86	0.018
regulation of gene expression epigenetic	GO:0040029	11	0.018
oxidoreduction coenzyme metabolic process	GO:0006733	1	0.018
cellular response to decreased oxygen levels	GO:0036294	1	0.018
maintenance of location	GO:0051235	4	0.017
lipid storage	GO:0019915	1	0.017
ion transport	GO:0006811	114	0.017	Worm
negative regulation of kinase activity	GO:0033673	4	0.017
cell proliferation	GO:0008283	80	0.017
determination of left right symmetry	GO:0007368	179	0.017
cellular component assembly involved in morphogenesis	GO:0010927	107	0.016
positive regulation of heart contraction	GO:0045823	2	0.016
ribonucleoside monophosphate catabolic process	GO:0009158	4	0.016
regulation of multicellular organismal development	GO:2000026	223	0.016
organonitrogen compound metabolic process	GO:1901564	74	0.016	Yeast Worm
protein import	GO:0017038	3	0.016
cognition	GO:0050890	1	0.016
single organism organelle organization	GO:1902589	199	0.015
histone deacetylation	GO:0016575	2	0.015
cofactor metabolic process	GO:0051186	15	0.015
tissue regeneration	GO:0042246	74	0.015
response to oxygen containing compound	GO:1901700	55	0.015
response to wounding	GO:0009611	116	0.015
inorganic cation transmembrane transport	GO:0098662	50	0.015	Worm
nucleoside monophosphate catabolic process	GO:0009125	4	0.015
behavior	GO:0007610	74	0.015	Worm
oogenesis	GO:0048477	14	0.014
nucleobase containing small molecule metabolic process	GO:0055086	32	0.014	Yeast Worm
nitrogen compound metabolic process	GO:0006807	319	0.014	Yeast Worm
detection of abiotic stimulus	GO:0009582	24	0.014
regulation of circadian rhythm	GO:0042752	4	0.014
female gamete generation	GO:0007292	14	0.014
phosphorus metabolic process	GO:0006793	109	0.014	Yeast Worm
hemopoiesis	GO:0030097	183	0.014
amine metabolic process	GO:0009308	2	0.014
cellular response to chemical stimulus	GO:0070887	157	0.014
nucleoside metabolic process	GO:0009116	11	0.014	Yeast Worm
response to stress	GO:0006950	263	0.013
apoptotic process	GO:0006915	116	0.013
cellular biosynthetic process	GO:0044249	286	0.013	Worm
organic cyclic compound metabolic process	GO:1901360	301	0.013	Yeast Worm
single organism biosynthetic process	GO:0044711	71	0.013	Worm
regeneration	GO:0031099	91	0.013
response to drug	GO:0042493	3	0.013
response to hydrogen peroxide	GO:0042542	3	0.012
organelle organization	GO:0006996	227	0.012
reproductive process	GO:0022414	40	0.012	Worm
response to external biotic stimulus	GO:0043207	97	0.012
intracellular estrogen receptor signaling pathway	GO:0030520	3	0.012
protein import into nucleus	GO:0006606	3	0.012
regulation of neurogenesis	GO:0050767	87	0.012
gastrulation	GO:0007369	208	0.012
fin regeneration	GO:0031101	51	0.012
monocarboxylic acid catabolic process	GO:0072329	3	0.012
cellular amine metabolic process	GO:0044106	2	0.012
single organism transport	GO:0044765	206	0.012	Worm
membrane repolarization	GO:0086009	2	0.012
regulation of myotube differentiation	GO:0010830	2	0.012
synaptic transmission cholinergic	GO:0007271	4	0.012
digestive tract morphogenesis	GO:0048546	231	0.012
negative regulation of multicellular organismal process	GO:0051241	69	0.011
nuclear transport	GO:0051169	4	0.011
phosphate containing compound metabolic process	GO:0006796	108	0.011	Yeast Worm
response to topologically incorrect protein	GO:0035966	2	0.011
circadian sleep wake cycle sleep	GO:0050802	1	0.011
regulation of cardiac muscle contraction	GO:0055117	2	0.011
peptide transport	GO:0015833	1	0.011
phagocytosis	GO:0006909	3	0.011
neurotransmitter transport	GO:0006836	2	0.011
angiogenesis	GO:0001525	158	0.011
cellular nitrogen compound metabolic process	GO:0034641	290	0.011	Yeast Worm
gamete generation	GO:0007276	33	0.011
tissue remodeling	GO:0048771	4	0.011
determination of bilateral symmetry	GO:0009855	204	0.011
response to other organism	GO:0051707	97	0.011
inorganic ion transmembrane transport	GO:0098660	57	0.011	Worm
regulation of nervous system development	GO:0051960	90	0.011
purine nucleoside monophosphate catabolic process	GO:0009128	4	0.010
hematopoietic or lymphoid organ development	GO:0048534	191	0.010
cell part morphogenesis	GO:0032990	246	0.010
centrosome organization	GO:0051297	1	0.010
ion transmembrane transport	GO:0034220	91	0.010	Worm
negative regulation of macromolecule metabolic process	GO:0010605	76	0.010
cellular component disassembly	GO:0022411	1	0.010
neurotransmitter secretion	GO:0007269	2	0.010
purine nucleoside triphosphate biosynthetic process	GO:0009145	2	0.010	Worm

cyc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.203
nervous system disease	DOID:863	0.043
eye and adnexa disease	DOID:1492	0.042
eye disease	DOID:5614	0.042
sensory system disease	DOID:0050155	0.042
cancer	DOID:162	0.039
disease of cellular proliferation	DOID:14566	0.039
disease of metabolism	DOID:0014667	0.034
organ system cancer	DOID:0050686	0.031
inherited metabolic disorder	DOID:655	0.027
mitochondrial metabolism disease	DOID:700	0.027
endocrine gland cancer	DOID:170	0.018
muscle tissue disease	DOID:66	0.018
muscular disease	DOID:0080000	0.018
musculoskeletal system disease	DOID:17	0.018
cardiovascular system disease	DOID:1287	0.015

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network