Danio rerio

12 known processes

ap2a1

adaptor-related protein complex 2, alpha 1 subunit

ap2a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of establishment of protein localizationGO:007020140.440
larval developmentGO:000216420.345
positive regulation of cellular component biogenesisGO:004408930.299
single organism organelle organizationGO:19025891990.290
cellular component biogenesisGO:00440851780.256
single organism localizationGO:19025782250.252
cellular component assemblyGO:00226071700.247
cellular component movementGO:00069283350.224
transportGO:00068102200.223
protein metabolic processGO:00195381830.222
regulation of developmental processGO:00507932470.217
neuron differentiationGO:00301823530.215
regulation of protein transportGO:005122330.209
agingGO:000756820.207
establishment of localizationGO:00512342440.206
single organism transportGO:00447652060.205
pole plasm assemblyGO:000731540.201
ras protein signal transductionGO:000726570.201
compound eye developmentGO:004874920.196
regulation of signal transductionGO:00099662250.195
negative regulation of ras protein signal transductionGO:004658010.193
cell surface receptor signaling pathwayGO:00071663250.190
cytokinesisGO:000091030.186
microtubule organizing center organizationGO:003102310.179
organelle assemblyGO:00709251100.171
cell cycleGO:0007049930.168
centrosome organizationGO:005129710.168
cell cycle processGO:0022402530.164
regulation of cell communicationGO:00106462320.163
oocyte axis specificationGO:000730950.160
regulation of signalingGO:00230512350.160
establishment of organelle localizationGO:0051656450.158
meiotic nuclear divisionGO:000712640.150
oocyte anterior posterior axis specificationGO:000731440.146
signal transductionGO:00071654550.143
cytoskeleton dependent cytokinesisGO:006164030.141
regulation of multicellular organismal processGO:00512392770.141
regulation of protein import into nucleusGO:004230620.140
protein import into nucleusGO:000660630.139
regulation of gtp catabolic processGO:003312420.139
microtubule based processGO:0007017600.139
oocyte constructionGO:000730850.138
regulation of cell deathGO:00109411030.136
single organism cellular localizationGO:1902580460.133
regulation of synapse assemblyGO:005196330.130
cell projection morphogenesisGO:00488582440.127
endosomal transportGO:001619720.125
neuron developmentGO:00486662620.125
eye developmentGO:00016542770.124
regulation of protein localization to nucleusGO:190018020.123
regulation of multicellular organismal developmentGO:20000262230.122
protein localization to nucleusGO:003450430.122
positive regulation of transportGO:005105020.121
nuclear migrationGO:000709730.120
regulation of synapse organizationGO:005080730.120
fertilizationGO:000956630.120
cellular nitrogen compound metabolic processGO:00346412900.119
establishment of protein localization to organelleGO:007259440.119
regulation of cytoplasmic transportGO:190364940.118
synaptic growth at neuromuscular junctionGO:005112420.117
cellular localizationGO:0051641970.114
cytoskeleton organizationGO:0007010960.114
regulation of macromolecule metabolic processGO:00602553170.114
establishment of localization in cellGO:0051649770.113
protein localization to plasma membraneGO:007265910.112
cytoplasm organizationGO:000702840.112
maintenance of locationGO:005123540.111
single fertilizationGO:000733830.111
organonitrogen compound metabolic processGO:1901564740.110
cellular aromatic compound metabolic processGO:00067252950.109
segmentationGO:0035282970.109
negative regulation of cytoplasmic transportGO:190365020.108
single organismal cell cell adhesionGO:0016337290.107
tube morphogenesisGO:00352393490.106
generation of neuronsGO:00486993850.105
gtp metabolic processGO:004603940.105
protein targeting to nucleusGO:004474430.105
organic cyclic compound metabolic processGO:19013603010.105
regulation of localizationGO:00328791040.105
maternal determination of anterior posterior axis embryoGO:000835840.104
regulation of transportGO:0051049450.103
regulation of cellular component organizationGO:0051128860.102
negative regulation of small gtpase mediated signal transductionGO:005105810.102
regionalizationGO:00030022740.101
nuclear importGO:005117030.100
extrinsic apoptotic signaling pathwayGO:009719130.099
organelle localizationGO:0051640490.098
regulation of synaptic growth at neuromuscular junctionGO:000858210.098
angiogenesisGO:00015251580.097
cell morphogenesisGO:00009022890.097
cell morphogenesis involved in differentiationGO:00009041950.096
nuclear transportGO:005116940.095
guanosine containing compound metabolic processGO:190106840.095
protein importGO:001703830.095
guanosine containing compound catabolic processGO:190106920.093
myeloid cell differentiationGO:0030099860.092
anterior posterior pattern specificationGO:00099521520.092
mitotic cell cycleGO:0000278640.091
heterocycle metabolic processGO:00464832900.091
cell deathGO:00082191210.090
mesenchyme developmentGO:00604851270.087
sensory organ developmentGO:00074233930.087
axonogenesisGO:00074091520.087
regulation of intracellular protein transportGO:003315730.087
regulation of rac protein signal transductionGO:003502010.086
positive regulation of biological processGO:00485182530.086
developmental growthGO:00485891660.085
macromolecule localizationGO:0033036540.085
regulation of gene expressionGO:00104682650.085
positive regulation of canonical wnt signaling pathwayGO:009026340.084
regulation of response to stimulusGO:00485832690.083
rna localizationGO:000640340.083
regulation of organelle assemblyGO:190211540.083
negative regulation of signal transductionGO:0009968940.082
negative regulation of mapk cascadeGO:004340940.081
carbohydrate derivative metabolic processGO:1901135610.079
nucleocytoplasmic transportGO:000691340.078
cell morphogenesis involved in neuron differentiationGO:00486671630.077
small gtpase mediated signal transductionGO:000726480.077
positive regulation of gtp catabolic processGO:003312610.076
macroautophagyGO:001623610.075
mitotic nuclear divisionGO:0007067180.075
negative regulation of intracellular transportGO:003238730.074
embryo development ending in birth or egg hatchingGO:00097922710.073
nuclear divisionGO:0000280230.073
regulation of rna metabolic processGO:00512522240.073
positive regulation of catabolic processGO:000989640.072
establishment of spindle localizationGO:0051293120.072
multicellular organism growthGO:003526440.072
central nervous system developmentGO:00074173870.071
mitotic cell cycle processGO:1903047480.071
regulation of nucleocytoplasmic transportGO:004682220.071
regulation of biological qualityGO:00650082630.071
regulation of protein targetingGO:190353320.070
regulation of intracellular signal transductionGO:1902531570.069
pronuclear migrationGO:003504610.069
cellular response to external stimulusGO:007149620.069
neuron projection morphogenesisGO:00488121610.069
spindle assemblyGO:005122520.069
cognitionGO:005089010.068
protein secretionGO:000930610.068
protein acylationGO:004354330.067
microtubule cytoskeleton organizationGO:0000226330.067
negative regulation of biological processGO:00485193040.067
protein complex subunit organizationGO:0071822460.066
neuron projection developmentGO:00311751800.066
cellular nitrogen compound biosynthetic processGO:00442712180.065
nitrogen compound metabolic processGO:00068073190.065
centrosome cycleGO:000709810.064
apoptotic processGO:00069151160.064
blood vessel morphogenesisGO:00485142160.064
oocyte differentiationGO:0009994140.063
phosphate containing compound metabolic processGO:00067961080.063
negative regulation of map kinase activityGO:004340720.063
negative regulation of synapse assemblyGO:005196420.062
sexual reproductionGO:0019953360.061
cellular macromolecule localizationGO:0070727210.060
macromolecular complex subunit organizationGO:0043933740.059
blood vessel developmentGO:00015682460.059
single organism nuclear importGO:190259330.056
positive regulation of cellular catabolic processGO:003133130.056
nucleobase containing compound metabolic processGO:00061392740.056
chordate embryonic developmentGO:00430092710.056
developmental maturationGO:0021700340.055
regulation of nucleoside metabolic processGO:000911820.055
peptidyl lysine acetylationGO:001839420.055
positive regulation of striated muscle cell differentiationGO:005115510.055
cellular amine metabolic processGO:004410620.054
programmed cell deathGO:00125011190.054
chemosensory behaviorGO:000763510.053
regulation of cellular amine metabolic processGO:003323800.053
stem cell divisionGO:001714510.052
regulation of gtpase activityGO:004308720.052
cellular response to extracellular stimulusGO:003166820.052
regulation of protein catabolic processGO:004217610.051
phagocytosisGO:000690930.051
cell part morphogenesisGO:00329902460.051
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.051
regulation of purine nucleotide catabolic processGO:003312120.051
gene expressionGO:00104672520.051
digestive system developmentGO:00551232890.050
axis specificationGO:0009798430.050
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.050
single organism intracellular transportGO:1902582250.050
response to external stimulusGO:00096052640.049
positive regulation of cellular processGO:00485222010.049
regulation of metabolic processGO:00192223590.049
rna transportGO:005065820.048
cortical actin cytoskeleton organizationGO:003086610.048
system processGO:00030081850.047
neurotransmitter transportGO:000683620.047
meiosis iGO:000712710.047
organic substance catabolic processGO:1901575280.047
protein localizationGO:0008104400.047
ion homeostasisGO:0050801410.047
immune system processGO:00023762410.046
regulation of nucleotide catabolic processGO:003081120.046
organelle organizationGO:00069962270.046
negative regulation of kinase activityGO:003367340.046
intracellular transportGO:0046907320.046
somite developmentGO:0061053960.045
digestive tract developmentGO:00485652650.045
endosome to lysosome transportGO:000833310.044
cell growthGO:0016049570.044
cellular protein metabolic processGO:00442671290.044
macromolecule modificationGO:00434121110.044
cortical cytoskeleton organizationGO:003086510.043
organic cyclic compound biosynthetic processGO:19013622230.043
negative regulation of protein phosphorylationGO:000193340.043
mesoderm developmentGO:0007498880.042
amine metabolic processGO:000930820.042
negative regulation of cell communicationGO:0010648960.042
growthGO:00400071740.042
positive regulation of cellular amino acid metabolic processGO:004576400.042
reactive oxygen species metabolic processGO:007259360.042
stem cell developmentGO:0048864820.041
regulation of peptidyl tyrosine phosphorylationGO:005073010.041
intracellular mrna localizationGO:000829810.041
positive regulation of cellular amine metabolic processGO:003324000.041
extracellular matrix organizationGO:0030198270.041
cellular component disassemblyGO:002241110.040
gtp catabolic processGO:000618420.040
single organism metabolic processGO:00447102170.040
regulation of programmed cell deathGO:00430671010.039
axon developmentGO:00615641660.039
regulation of molecular functionGO:0065009700.039
regulation of multicellular organism growthGO:004001440.039
golgi vesicle transportGO:004819330.039
cell fate commitmentGO:0045165990.039
positive regulation of apoptotic signaling pathwayGO:200123510.039
hatchingGO:003518840.039
cell projection organizationGO:00300302840.038
oocyte developmentGO:0048599140.038
macromolecular complex assemblyGO:0065003350.038
negative regulation of nucleocytoplasmic transportGO:004682320.038
cellular response to nutrient levelsGO:003166920.038
autophagyGO:000691440.038
mitotic cytokinesisGO:000028130.037
cellular response to starvationGO:000926710.037
regulation of erythrocyte differentiationGO:004564620.037
protein polymerizationGO:005125840.037
regulation of nervous system developmentGO:0051960900.037
negative regulation of signalingGO:0023057960.037
regulation of cellular amino acid metabolic processGO:000652100.036
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.036
signal transduction by phosphorylationGO:0023014180.036
developmental growth involved in morphogenesisGO:0060560860.036
regulation of cell substrate adhesionGO:001081010.036
adult behaviorGO:003053420.036
response to stressGO:00069502630.036
mediolateral intercalationGO:006003130.036
transcription dna templatedGO:00063511810.036
somitogenesisGO:0001756870.036
localization of cellGO:00516742440.036
organic substance transportGO:0071702580.035
deathGO:00162651210.035
er to golgi vesicle mediated transportGO:000688810.035
exocytosisGO:000688710.034
intracellular signal transductionGO:0035556850.034
regulation of cell activationGO:005086510.034
ribonucleoside monophosphate catabolic processGO:000915840.034
positive regulation of synapse assemblyGO:005196510.034
regulation of cell matrix adhesionGO:000195210.034
actin polymerization or depolymerizationGO:000815420.034
cellular amino acid metabolic processGO:000652070.034
negative regulation of cellular processGO:00485232830.034
epithelial cell differentiationGO:00308551160.034
membrane fusionGO:006102520.033
cell maturationGO:0048469230.033
phosphorus metabolic processGO:00067931090.033
vasculature developmentGO:00019442780.033
positive regulation of purine nucleotide catabolic processGO:003312310.033
regulation of cytokine productionGO:000181730.033
digestive tract morphogenesisGO:00485462310.033
protein modification processGO:00362111000.033
regulation of rho protein signal transductionGO:003502320.033
regulation of protein localization to plasma membraneGO:190307610.032
regulation of autophagyGO:001050630.032
b cell activationGO:004211320.032
positive regulation of cell divisionGO:005178120.031
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.031
rna modificationGO:000945120.031
regulation of phosphorylationGO:0042325260.031
adherens junction organizationGO:003433240.031
heart developmentGO:00075073130.031
negative regulation of protein transportGO:005122430.031
mononuclear cell proliferationGO:003294310.031
regulation of protein complex assemblyGO:004325430.031
vesicle localizationGO:0051648270.031
heterocycle biosynthetic processGO:00181302150.030
lysosomal transportGO:000704120.030
olfactory lobe developmentGO:002198840.030
regulation of sodium ion transmembrane transportGO:190230510.030
convergent extensionGO:00600261180.030
aromatic compound biosynthetic processGO:00194382170.030
macromolecule biosynthetic processGO:00090592270.030
locomotionGO:00400113130.029
multi organism reproductive processGO:0044703360.029
regulation of nucleobase containing compound metabolic processGO:00192192500.029
multi organism processGO:00517041340.029
oxoacid metabolic processGO:0043436310.029
regulation of rna biosynthetic processGO:20011412130.029
reproductionGO:0000003400.029
negative regulation of protein serine threonine kinase activityGO:007190120.029
organic cyclic compound catabolic processGO:1901361150.029
neural tube developmentGO:0021915620.029
vacuolar transportGO:000703420.029
regulation of oocyte developmentGO:006028130.029
positive regulation of gtpase activityGO:004354710.029
positive regulation of response to stimulusGO:0048584800.029
protein acetylationGO:000647320.028
regulation of reproductive processGO:200024140.028
cellular component morphogenesisGO:00329893360.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.028
spermatid differentiationGO:004851520.028
establishment of synaptic vesicle localizationGO:009748010.028
organism emergence from protective structureGO:007168440.028
nucleic acid templated transcriptionGO:00976591810.028
leukocyte proliferationGO:007066110.028
spindle localizationGO:0051653120.027
cell divisionGO:0051301200.027
regulation of cell differentiationGO:00455951420.027
astral microtubule organizationGO:003095310.027
hemopoiesisGO:00300971830.027
vesicle mediated transportGO:0016192220.027
regulation of vesicle mediated transportGO:006062790.027
negative regulation of intracellular protein transportGO:009031730.027
cellular ketone metabolic processGO:0042180110.027
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.027
regulation of phGO:000688530.027
regulation of intracellular phGO:005145310.027
membrane invaginationGO:001032410.026
positive regulation of cell deathGO:0010942290.026
extracellular structure organizationGO:0043062270.026
regulation of neurological system processGO:003164420.026
negative regulation of multicellular organismal processGO:0051241690.026
proton transportGO:001599270.026
striated muscle cell differentiationGO:00511461290.026
rostrocaudal neural tube patterningGO:0021903290.026
viral processGO:001603210.026
negative regulation of protein import into nucleusGO:004230820.026
regulation of catalytic activityGO:0050790550.026
negative regulation of catabolic processGO:000989530.026
regulation of protein depolymerizationGO:190187910.026
cellular process involved in reproduction in multicellular organismGO:0022412280.026
positive regulation of nucleotide catabolic processGO:003081310.025
epithelial tube morphogenesisGO:00605621480.025
central nervous system neuron developmentGO:0021954290.025
response to chemicalGO:00422213200.025
regulation of bindingGO:005109830.025
positive regulation of muscle cell differentiationGO:005114910.025
cell substrate adhesionGO:003158940.025
actomyosin structure organizationGO:0031032530.025
negative regulation of protein localization to nucleusGO:190018120.025
carboxylic acid metabolic processGO:0019752220.025
rna biosynthetic processGO:00327741810.025
regulation of cell maturationGO:190342910.025
meiotic cell cycle processGO:190304630.025
vesicle organizationGO:001605060.024
peptidyl serine phosphorylationGO:001810510.024
zymogen activationGO:003163830.024
forebrain developmentGO:0030900960.024
regulation of protein bindingGO:004339330.024
cellular biosynthetic processGO:00442492860.024
cytokinetic processGO:003250620.024
single organism reproductive processGO:0044702400.024
regulation of nitrogen compound metabolic processGO:00511712510.024
formation of primary germ layerGO:0001704620.024
internal peptidyl lysine acetylationGO:001839320.024
cellular macromolecule biosynthetic processGO:00346452240.023
regulation of cellular localizationGO:0060341120.023
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.023
protein complex assemblyGO:0006461300.023
positive regulation of cell cycleGO:004578730.023
regulation of response to biotic stimulusGO:000283120.023
wnt signaling pathwayGO:0016055800.023
regulation of organelle organizationGO:0033043290.023
macromolecular complex disassemblyGO:003298410.023
cellular monovalent inorganic cation homeostasisGO:003000420.023
immune system developmentGO:00025201910.023
response to abiotic stimulusGO:00096281220.023
wnt signaling pathway planar cell polarity pathwayGO:006007140.023
nucleobase containing small molecule metabolic processGO:0055086320.023
cellular protein modification processGO:00064641000.022
protein complex disassemblyGO:004324110.022
embryonic pattern specificationGO:0009880440.022
cell migrationGO:00164772370.022
cell substrate junction assemblyGO:000704420.022
protein depolymerizationGO:005126110.022
cellular macromolecule metabolic processGO:00442603910.022
regulation of cell developmentGO:00602841000.022
apoptotic process involved in developmentGO:190274220.022
brain developmentGO:00074202930.021
phagocytosis engulfmentGO:000691110.021
hematopoietic or lymphoid organ developmentGO:00485341910.021
response to organic substanceGO:00100331530.021
regulation of cellular phGO:003064110.021
regulation of establishment of planar polarityGO:009017540.021
regulation of cellular metabolic processGO:00313233200.021
neural tube patterningGO:0021532330.021
muscle cell differentiationGO:00426921390.021
protein complex biogenesisGO:0070271300.021
phosphorylationGO:0016310690.021
morphogenesis of an epitheliumGO:00020093330.021
regulation of phosphate metabolic processGO:0019220430.021
negative chemotaxisGO:005091910.021
interferon beta productionGO:003260810.021
centrosome duplicationGO:005129810.020
nucleobase containing compound biosynthetic processGO:00346542050.020
amino acid transportGO:000686520.020
anterior posterior axis specificationGO:0009948200.020
developmental programmed cell deathGO:001062340.020
organelle fissionGO:0048285230.020
immune responseGO:0006955280.020
peptidyl serine modificationGO:001820920.020
positive regulation of neuron apoptotic processGO:004352510.020
locomotory behaviorGO:0007626340.020
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.019
regulation of cellular ketone metabolic processGO:001056570.019
cytoplasmic transportGO:0016482110.019
regulation of growthGO:0040008420.019
positive regulation of multicellular organismal processGO:0051240520.019
cellular macromolecular complex assemblyGO:0034622240.019
organophosphate metabolic processGO:0019637370.019
regulation of anterior head developmentGO:200074220.019
oogenesisGO:0048477140.019
female meiotic divisionGO:000714320.019
cellular component assembly involved in morphogenesisGO:00109271070.019
muscle structure developmentGO:00610611960.019
somatic muscle developmentGO:000752540.019
regulation of cell growthGO:0001558290.019
positive regulation of nucleoside metabolic processGO:004597910.019
gland developmentGO:00487321430.019
negative regulation of leukocyte differentiationGO:190210610.019
skeletal system developmentGO:00015011810.019
meiotic spindle organizationGO:000021210.019
negative regulation of autophagyGO:001050710.019
defense response to other organismGO:0098542330.019
regulation of nucleic acid templated transcriptionGO:19035062130.018
microtubule based movementGO:0007018330.018
cation transportGO:0006812810.018
cellular protein complex assemblyGO:0043623190.018
forebrain cell migrationGO:002188510.018
aromatic compound catabolic processGO:0019439150.018
regulation of cell shapeGO:000836010.018
rho protein signal transductionGO:000726650.018
regulation of protein metabolic processGO:0051246560.018
internal protein amino acid acetylationGO:000647520.018
determination of left right symmetryGO:00073681790.018
actin filament bundle assemblyGO:005101760.018
purine nucleotide metabolic processGO:0006163270.018
positive regulation of cytosolic calcium ion concentrationGO:000720440.018
lamellipodium organizationGO:009758110.018
establishment of rna localizationGO:005123630.018
positive regulation of nitrogen compound metabolic processGO:0051173690.018
actin filament organizationGO:0007015150.018
embryonic skeletal system developmentGO:0048706970.018
lymphocyte proliferationGO:004665110.018
regulation of ras gtpase activityGO:003231820.018
regulation of response to extracellular stimulusGO:003210410.018
signal transduction in absence of ligandGO:003803410.017
positive regulation of notch signaling pathwayGO:004574730.017
ribosomal small subunit biogenesisGO:004227420.017
regulation of microtubule cytoskeleton organizationGO:007050730.017
response to nutrientGO:000758430.017
establishment of mitotic spindle localizationGO:0040001120.017
regulation of synaptic plasticityGO:004816710.017
meiotic chromosome segregationGO:004513230.017
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.017
biosynthetic processGO:00090582940.017
response to nutrient levelsGO:0031667100.017
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.017
organic acid metabolic processGO:0006082310.017
centrosome localizationGO:005164210.017
positive regulation of cytoskeleton organizationGO:005149530.017
meiosis iiGO:000713510.017
single organism behaviorGO:0044708240.017
positive regulation of nucleobase containing compound metabolic processGO:0045935690.017
regulation of developmental growthGO:0048638380.017
mitotic metaphase plate congressionGO:000708010.017
nucleoside phosphate metabolic processGO:0006753280.017
heterocycle catabolic processGO:0046700150.017
organelle transport along microtubuleGO:007238410.016
negative regulation of macromolecule metabolic processGO:0010605760.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
regulation of photoreceptor cell differentiationGO:004653220.016
regulation of macromolecule biosynthetic processGO:00105562250.016
myofibril assemblyGO:0030239480.016
positive regulation of cell activationGO:005086710.016
multi organism cellular processGO:004476420.016
erk1 and erk2 cascadeGO:007037140.016
i kappab kinase nf kappab signalingGO:000724940.016
organic substance biosynthetic processGO:19015762890.016

ap2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.203
nervous system diseaseDOID:86300.060
cancerDOID:16200.035
disease of cellular proliferationDOID:1456600.035
organ system cancerDOID:005068600.035