Danio rerio

71 known processes

tef

thyrotroph embryonic factor

(Aliases: tefb,tefa,wu:fb11h02,tefbeta,wu:fa12f02,zTEF[a])

tef biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
steroid hormone secretionGO:003592910.929
regulation of endocrine processGO:004406020.810
circadian regulation of gene expressionGO:003292280.734
endocrine processGO:005088620.678
regulation of circadian rhythmGO:004275240.663
entrainment of circadian clock by photoperiodGO:004315310.534
endocrine hormone secretionGO:006098620.477
regulation of hormone secretionGO:004688320.468
entrainment of circadian clockGO:000964920.465
hormone transportGO:000991420.372
macromolecule biosynthetic processGO:00090592270.337
response to stressGO:00069502630.313
regulation of nucleic acid templated transcriptionGO:19035062130.303
defense responseGO:0006952470.290
cellular aromatic compound metabolic processGO:00067252950.263
hormone secretionGO:004687920.256
nucleobase containing compound metabolic processGO:00061392740.249
regulation of gene expressionGO:00104682650.241
regulation of macromolecule biosynthetic processGO:00105562250.207
multicellular organism growthGO:003526440.191
photoperiodismGO:0009648110.185
organic substance biosynthetic processGO:19015762890.168
regulation of metabolic processGO:00192223590.165
immune responseGO:0006955280.156
heterocycle metabolic processGO:00464832900.149
larval developmentGO:000216420.145
regulation of nucleobase containing compound metabolic processGO:00192192500.143
organic cyclic compound biosynthetic processGO:19013622230.143
response to bacteriumGO:0009617580.141
response to external stimulusGO:00096052640.141
Fly
transportGO:00068102200.139
nucleic acid templated transcriptionGO:00976591810.137
cellular macromolecule biosynthetic processGO:00346452240.133
positive regulation of biological processGO:00485182530.131
regulation of cellular macromolecule biosynthetic processGO:20001122220.129
regulation of multicellular organism growthGO:004001440.123
response to biotic stimulusGO:0009607970.123
negative regulation of secretionGO:005104820.122
regulation of nitrogen compound metabolic processGO:00511712510.121
regulation of hormone levelsGO:0010817210.120
heterocycle biosynthetic processGO:00181302150.118
response to other organismGO:0051707970.116
regulation of transcription dna templatedGO:00063552130.113
regulation of multicellular organismal processGO:00512392770.106
cellular nitrogen compound metabolic processGO:00346412900.105
biosynthetic processGO:00090582940.099
circadian rhythmGO:0007623190.099
Fly
cell surface receptor signaling pathwayGO:00071663250.095
nucleobase containing compound biosynthetic processGO:00346542050.095
rna metabolic processGO:00160702190.094
multi organism processGO:00517041340.093
cellular nitrogen compound biosynthetic processGO:00442712180.089
lipid homeostasisGO:005508830.087
organic cyclic compound metabolic processGO:19013603010.087
single organism metabolic processGO:00447102170.085
Fly
response to uvGO:000941130.085
regulation of cellular biosynthetic processGO:00313262450.081
rna biosynthetic processGO:00327741810.081
cellular macromolecule metabolic processGO:00442603910.080
gene expressionGO:00104672520.080
locomotor rhythmGO:004547530.080
nucleic acid metabolic processGO:00903042440.076
establishment of localizationGO:00512342440.075
regulation of transcription from rna polymerase ii promoterGO:00063571140.075
Mouse Rat Fly
negative regulation of hormone secretionGO:004688820.074
regulation of steroid hormone secretionGO:200083110.073
positive regulation of canonical wnt signaling pathwayGO:009026340.072
regulation of developmental processGO:00507932470.070
nitrogen compound metabolic processGO:00068073190.069
proteolysis involved in cellular protein catabolic processGO:005160330.068
hematopoietic or lymphoid organ developmentGO:00485341910.067
system processGO:00030081850.063
regulation of biological qualityGO:00650082630.063
transcription dna templatedGO:00063511810.061
regulation of biosynthetic processGO:00098892500.061
positive regulation of nucleobase containing compound metabolic processGO:0045935690.060
negative regulation of biological processGO:00485193040.060
regulation of response to stimulusGO:00485832690.059
establishment of localization in cellGO:0051649770.059
central nervous system developmentGO:00074173870.057
regulation of cell communicationGO:00106462320.057
regulation of rna biosynthetic processGO:20011412130.056
regulation of rna metabolic processGO:00512522240.056
regulation of cell differentiationGO:00455951420.056
glucose homeostasisGO:004259310.056
response to external biotic stimulusGO:0043207970.056
regulation of system processGO:0044057400.055
protein targeting to nucleusGO:004474430.053
immune system processGO:00023762410.052
mesoderm developmentGO:0007498880.049
nuclear transportGO:005116940.048
cellular protein catabolic processGO:004425740.045
response to radiationGO:0009314510.045
intestinal absorptionGO:005089220.045
lipid metabolic processGO:0006629520.044
Fly
negative regulation of protein kinase activityGO:000646940.044
regulation of macromolecule metabolic processGO:00602553170.044
negative regulation of cellular biosynthetic processGO:0031327550.043
regulation of signal transductionGO:00099662250.043
regulation of tube sizeGO:003515020.043
negative regulation of metabolic processGO:0009892860.043
signal transductionGO:00071654550.041
regulation of protein modification by small protein conjugation or removalGO:190332030.041
carboxylic acid metabolic processGO:0019752220.041
response to alkaloidGO:004327920.041
ubiquitin dependent protein catabolic processGO:000651130.040
maintenance of locationGO:005123540.039
mitochondrion organizationGO:000700540.039
positive regulation of cellular processGO:00485222010.039
positive regulation of nitrogen compound metabolic processGO:0051173690.039
meiotic chromosome segregationGO:004513230.038
negative regulation of mitosisGO:004583930.038
response to chemicalGO:00422213200.038
Fly
negative regulation of gene expressionGO:0010629650.037
rhythmic processGO:0048511210.037
Fly
protein importGO:001703830.037
bmp signaling pathwayGO:0030509520.037
response to organic substanceGO:00100331530.037
cellular ketone metabolic processGO:0042180110.037
agingGO:000756820.036
single organism transportGO:00447652060.036
regulation of protein ubiquitinationGO:003139630.035
negative regulation of rna metabolic processGO:0051253480.035
amine metabolic processGO:000930820.035
regulation of primary metabolic processGO:00800903110.034
homeostatic processGO:00425921420.034
photoreceptor cell developmentGO:0042461400.034
neuron differentiationGO:00301823530.034
liver developmentGO:0001889960.033
negative regulation of secretion by cellGO:190353120.033
cellular biosynthetic processGO:00442492860.032
carbohydrate homeostasisGO:003350010.032
chordate embryonic developmentGO:00430092710.032
protein metabolic processGO:00195381830.032
regulation of blood vessel sizeGO:005088020.032
germ line stem cell maintenanceGO:003071820.031
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.031
oxoacid metabolic processGO:0043436310.031
hepatocyte proliferationGO:007257420.031
regulation of signalingGO:00230512350.031
modification dependent macromolecule catabolic processGO:004363230.031
neuron developmentGO:00486662620.030
response to inorganic substanceGO:0010035380.030
peptide transportGO:001583310.030
negative regulation of cellular metabolic processGO:0031324770.030
regulation of skeletal muscle cell differentiationGO:200101410.030
muscle organ developmentGO:00075171010.030
circadian sleep wake cycle sleepGO:005080210.030
negative regulation of transcription dna templatedGO:0045892450.029
cellular protein metabolic processGO:00442671290.029
ribosomal small subunit biogenesisGO:004227420.028
circadian sleep wake cycleGO:004274520.028
dna metabolic processGO:0006259270.028
Fly
regulation of cytokine productionGO:000181730.028
embryo development ending in birth or egg hatchingGO:00097922710.028
ion transportGO:00068111140.028
aromatic compound biosynthetic processGO:00194382170.027
stem cell maintenanceGO:001982740.027
cellular amine metabolic processGO:004410620.027
organic acid metabolic processGO:0006082310.027
negative regulation of protein phosphorylationGO:000193340.027
regulation of cellular metabolic processGO:00313233200.027
protein import into nucleusGO:000660630.027
single organism nuclear importGO:190259330.027
i kappab kinase nf kappab signalingGO:000724940.027
regulation of epithelial cell proliferationGO:005067830.026
regulation of multicellular organismal developmentGO:20000262230.026
spindle assemblyGO:005122520.026
defense response to bacteriumGO:0042742220.025
cell substrate adhesionGO:003158940.025
protein modification processGO:00362111000.025
intracellular receptor signaling pathwayGO:0030522300.025
b cell activationGO:004211320.025
antimicrobial humoral responseGO:001973020.025
negative regulation of cellular processGO:00485232830.025
positive regulation of cell divisionGO:005178120.025
negative regulation of macromolecule biosynthetic processGO:0010558480.025
response to endogenous stimulusGO:0009719830.025
single organism localizationGO:19025782250.025
determination of bilateral symmetryGO:00098552040.025
regulation of alternative mrna splicing via spliceosomeGO:000038110.025
peptidyl serine phosphorylationGO:001810510.024
female sex differentiationGO:004666040.024
negative regulation of signal transductionGO:0009968940.024
homologous chromosome segregationGO:004514310.024
nuclear importGO:005117030.024
regulation of intracellular signal transductionGO:1902531570.024
generation of neuronsGO:00486993850.024
negative regulation of macromolecule metabolic processGO:0010605760.023
response to copper ionGO:0046688130.023
regulation of reproductive processGO:200024140.023
negative regulation of rna biosynthetic processGO:1902679450.023
lipid storageGO:001991510.023
proteasomal protein catabolic processGO:001049820.023
chemical homeostasisGO:0048878490.023
positive regulation of catabolic processGO:000989640.023
regulation of cellular amine metabolic processGO:003323800.022
regulation of skeletal muscle tissue developmentGO:004864140.022
transcription from rna polymerase ii promoterGO:0006366800.022
Mouse Rat Fly
regulation of lipid transportGO:003236840.022
response to ketoneGO:190165410.022
enzyme linked receptor protein signaling pathwayGO:00071671060.022
toll like receptor signaling pathwayGO:000222440.022
regulation of stem cell differentiationGO:200073640.022
eye developmentGO:00016542770.022
dna repairGO:000628160.021
hepaticobiliary system developmentGO:0061008980.021
growthGO:00400071740.021
Fly
regulation of circadian sleep wake cycle sleepGO:004518710.021
response to topologically incorrect proteinGO:003596620.021
carbohydrate biosynthetic processGO:001605110.021
negative regulation of steroid hormone secretionGO:200083210.021
protein localization to nucleusGO:003450430.020
regulation of receptor mediated endocytosisGO:004825940.020
positive regulation of multicellular organismal processGO:0051240520.020
response to hydrogen peroxideGO:004254230.020
transmembrane transportGO:00550851200.020
blood circulationGO:0008015870.020
negative regulation of kinase activityGO:003367340.020
digestive system developmentGO:00551232890.020
negative regulation of biosynthetic processGO:0009890550.019
nucleocytoplasmic transportGO:000691340.019
regulation of cellular amino acid metabolic processGO:000652100.019
response to oxygen radicalGO:000030520.019
regulation of cell activationGO:005086510.019
cellular response to starvationGO:000926710.019
cellular lipid metabolic processGO:0044255360.019
establishment of protein localization to organelleGO:007259440.019
negative regulation of response to stimulusGO:00485851040.019
innate immune response activating signal transductionGO:000275850.019
multicellular organismal metabolic processGO:004423620.019
regulation of localizationGO:00328791040.019
negative regulation of nitrogen compound metabolic processGO:0051172590.019
response to hormoneGO:0009725480.019
neurotransmitter transportGO:000683620.019
regulation of systemic arterial blood pressureGO:000307310.019
regulation of circadian sleep wake cycleGO:004274910.019
cellular response to stressGO:0033554620.019
developmental growthGO:00485891660.019
modification dependent protein catabolic processGO:001994130.018
regulation of nucleoside metabolic processGO:000911820.018
heart developmentGO:00075073130.018
regulation of wnt signaling pathwayGO:0030111530.018
energy reserve metabolic processGO:000611220.018
purine nucleoside monophosphate catabolic processGO:000912840.018
regulation of synaptic plasticityGO:004816710.018
extrinsic apoptotic signaling pathwayGO:009719130.018
behaviorGO:0007610740.018
cellular amide metabolic processGO:004360340.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
neurotransmitter secretionGO:000726920.018
regulation of protein catabolic processGO:004217610.018
cellular protein modification processGO:00064641000.017
regulation of defense responseGO:0031347140.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.017
pharyngeal system developmentGO:0060037180.017
autophagyGO:000691440.017
regulation of cellular ketone metabolic processGO:001056570.017
regulation of response to external stimulusGO:0032101310.017
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.017
mitochondrial transportGO:000683920.017
circulatory system processGO:0003013870.017
leukocyte proliferationGO:007066110.017
cell cell signalingGO:0007267520.017
alternative mrna splicing via spliceosomeGO:000038010.017
positive regulation of cellular catabolic processGO:003133130.016
regulation of blood pressureGO:000821710.016
protein polyubiquitinationGO:000020940.016
receptor internalizationGO:003162320.016
organic substance transportGO:0071702580.016
regulation of mrna splicing via spliceosomeGO:004802430.016
brain developmentGO:00074202930.016
defense response to other organismGO:0098542330.016
negative regulation of signalingGO:0023057960.016
common bile duct developmentGO:0061009130.016
cell agingGO:000756920.015
rna modificationGO:000945120.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.015
regulation of ion transmembrane transporter activityGO:003241220.015
pancreas developmentGO:0031016840.015
guanosine containing compound metabolic processGO:190106840.015
regulation of cellular protein catabolic processGO:190336210.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
fin developmentGO:0033333770.015
multicellular organismal homeostasisGO:0048871290.015
cellular response to dna damage stimulusGO:0006974240.015
mononuclear cell proliferationGO:003294310.015
response to lipidGO:0033993600.015
positive regulation of lymphocyte mediated immunityGO:000270810.015
regulation of inflammatory responseGO:005072720.014
head developmentGO:00603223030.014
negative regulation of multicellular organismal processGO:0051241690.014
regulation of receptor internalizationGO:000209020.014
cellular response to nutrient levelsGO:003166920.014
iron ion homeostasisGO:005507240.014
positive regulation of multi organism processGO:004390230.014
negative regulation of epithelial cell proliferationGO:005068010.014
camera type eye developmentGO:00430102220.014
macromolecule modificationGO:00434121110.014
regulation of neurotransmitter transportGO:005158810.014
regulation of gtpase activityGO:004308720.014
negative regulation of autophagyGO:001050710.014
meiotic cell cycle processGO:190304630.014
negative regulation of defense responseGO:003134820.014
cell growthGO:0016049570.014
cellular response to radiationGO:007147840.014
anion transportGO:0006820380.014
negative regulation of cell communicationGO:0010648960.013
cellular amino acid metabolic processGO:000652070.013
positive regulation of cell deathGO:0010942290.013
Worm
response to light stimulusGO:0009416460.013
one carbon compound transportGO:0019755140.013
mesenchyme developmentGO:00604851270.013
negative regulation of map kinase activityGO:004340720.013
regulation of protein complex assemblyGO:004325430.013
positive regulation of muscle tissue developmentGO:190186310.013
response to oxidative stressGO:0006979110.013
response to woundingGO:00096111160.013
locomotory behaviorGO:0007626340.013
positive regulation of secretionGO:005104710.013
locomotionGO:00400113130.013
b cell differentiationGO:003018310.013
oxidation reduction processGO:0055114410.013
regulation of bindingGO:005109830.012
cellular component disassemblyGO:002241110.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
regulation of epithelial to mesenchymal transitionGO:001071730.012
rhythmic behaviorGO:000762250.012
positive regulation of cellular amine metabolic processGO:003324000.012
positive regulation of immune effector processGO:000269930.012
response to organic cyclic compoundGO:0014070510.012
positive regulation of ras protein signal transductionGO:004657910.012
g protein coupled receptor signaling pathwayGO:0007186740.012
gtp catabolic processGO:000618420.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
phagocytosis engulfmentGO:000691110.012
muscle structure developmentGO:00610611960.012
response to oxygen containing compoundGO:1901700550.012
cellular localizationGO:0051641970.012
single organism biosynthetic processGO:0044711710.012
Fly
response to glucoseGO:000974930.012
microtubule based processGO:0007017600.012
regulation of jun kinase activityGO:004350630.012
insulin like growth factor receptor signaling pathwayGO:004800940.012
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.011
apoptotic processGO:00069151160.011
Worm
mitotic dna integrity checkpointGO:004477440.011
circadian sleep wake cycle processGO:002241020.011
positive regulation of developmental processGO:0051094500.011
positive regulation of macromolecule metabolic processGO:0010604930.011
protein stabilizationGO:005082120.011
positive regulation of transportGO:005105020.011
meiotic nuclear divisionGO:000712640.011
regulation of bmp signaling pathwayGO:0030510390.011
protein dephosphorylationGO:000647030.011
energy homeostasisGO:009700930.011
regulation of carbohydrate metabolic processGO:000610940.011
developmental cell growthGO:0048588520.011
cellular carbohydrate metabolic processGO:004426240.011
negative regulation of immune responseGO:005077720.011
regulation of canonical wnt signaling pathwayGO:0060828340.011
determination of left right asymmetry in lateral mesodermGO:0003140200.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
positive regulation of metabolic processGO:00098931080.011
regulation of receptor activityGO:001046920.011
positive regulation of cellular biosynthetic processGO:0031328680.011
cytokinesisGO:000091030.011
response to steroid hormoneGO:0048545350.011
regulation of wnt signaling pathway calcium modulating pathwayGO:000859130.011
regulation of calcium ion transportGO:005192420.011
programmed cell deathGO:00125011190.011
Worm
mitotic dna damage checkpointGO:004477340.011
negative regulation of mapk cascadeGO:004340940.011
ovulation cycle processGO:002260220.011
positive regulation of leukocyte mediated cytotoxicityGO:000191210.011
notochord developmentGO:0030903540.011
regulation of epidermis developmentGO:004568220.011
cellular response to decreased oxygen levelsGO:003629410.010
skeletal muscle organ developmentGO:0060538780.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
regulation of cardiac muscle tissue developmentGO:005502410.010
regulation of purine nucleotide catabolic processGO:003312120.010
atp catabolic processGO:000620040.010
regulation of protein metabolic processGO:0051246560.010
negative regulation of nuclear divisionGO:005178430.010
erk1 and erk2 cascadeGO:007037140.010
regulation of autophagyGO:001050630.010
protein localization to plasma membraneGO:007265910.010
membrane repolarizationGO:008600920.010
striated muscle tissue developmentGO:00147061100.010
positive regulation of cell killingGO:003134320.010
positive regulation of cytoskeleton organizationGO:005149530.010
inositol lipid mediated signalingGO:004801720.010
specification of symmetryGO:00097992040.010
gtp metabolic processGO:004603940.010
lymphocyte proliferationGO:004665110.010
positive regulation of cell cycleGO:004578730.010

tef disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.026
inherited metabolic disorderDOID:65500.020
nervous system diseaseDOID:86300.013
eye diseaseDOID:561400.013
disease of anatomical entityDOID:700.013
retinal diseaseDOID:567900.013
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013
organ system cancerDOID:005068600.011
gastrointestinal system cancerDOID:311900.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011