IMP: Integrative Multi-species Prediction

Danio rerio

59 known processes

mstnb

myostatin b

(Aliases: MGC109749,mstn,gdf8,zgc:109749)

ZFIN: ZDB-GENE-990415-165
Ensembl: ENSDARG00000069133
Entrez: 798441
UniProtKB: O42222

Process Predictions
Disease Predictions

mstnb biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
negative regulation of growth rate	GO:0045967	1	0.932
nucleobase containing compound metabolic process	GO:0006139	274	0.900	Worm
aromatic compound biosynthetic process	GO:0019438	217	0.873	Worm
regulation of gene expression	GO:0010468	265	0.843	Worm
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.841	Worm
gene expression	GO:0010467	252	0.833	Worm
defense response	GO:0006952	47	0.825	Worm
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.816	Worm
cellular aromatic compound metabolic process	GO:0006725	295	0.786	Worm
nucleic acid templated transcription	GO:0097659	181	0.778	Worm
response to chemical	GO:0042221	320	0.776
regulation of macromolecule metabolic process	GO:0060255	317	0.762	Worm
heterocycle biosynthetic process	GO:0018130	215	0.746	Worm
inner ear development	GO:0048839	126	0.725	Zebrafish
nitrogen compound metabolic process	GO:0006807	319	0.716	Worm
immune system process	GO:0002376	241	0.711
organic cyclic compound biosynthetic process	GO:1901362	223	0.704	Worm
cellular component assembly	GO:0022607	170	0.701
regulation of metabolic process	GO:0019222	359	0.694	Worm
striated muscle cell differentiation	GO:0051146	129	0.674
purine nucleotide metabolic process	GO:0006163	27	0.673
cellular macromolecule metabolic process	GO:0044260	391	0.672	Worm
heterocycle metabolic process	GO:0046483	290	0.671	Worm
regulation of primary metabolic process	GO:0080090	311	0.668	Worm
negative regulation of developmental process	GO:0051093	65	0.641
response to stress	GO:0006950	263	0.594	Worm
cellular nitrogen compound metabolic process	GO:0034641	290	0.572	Worm
regulation of multicellular organismal development	GO:2000026	223	0.541
positive regulation of cellular component biogenesis	GO:0044089	3	0.537
rna metabolic process	GO:0016070	219	0.530	Worm
locomotion	GO:0040011	313	0.514
nucleobase containing compound biosynthetic process	GO:0034654	205	0.480	Worm
neuron development	GO:0048666	262	0.461
organic substance biosynthetic process	GO:1901576	289	0.438	Worm
purine ribonucleotide metabolic process	GO:0009150	27	0.433
regulation of rna metabolic process	GO:0051252	224	0.431	Worm
negative regulation of cellular process	GO:0048523	283	0.421
organelle assembly	GO:0070925	110	0.411
cellular biosynthetic process	GO:0044249	286	0.408	Worm
ear development	GO:0043583	127	0.406	Zebrafish
regulation of cellular macromolecule biosynthetic process	GO:2000112	222	0.405	Worm
positive regulation of macromolecule metabolic process	GO:0010604	93	0.401	Worm
purine nucleotide biosynthetic process	GO:0006164	20	0.401
transcription dna templated	GO:0006351	181	0.396	Worm
organic cyclic compound metabolic process	GO:1901360	301	0.391	Worm
positive regulation of metabolic process	GO:0009893	108	0.387	Worm
nucleoside phosphate metabolic process	GO:0006753	28	0.381
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.376	Worm
biosynthetic process	GO:0009058	294	0.365	Worm
cellular protein complex assembly	GO:0043623	19	0.346
carbohydrate derivative metabolic process	GO:1901135	61	0.345
regulation of macromolecule biosynthetic process	GO:0010556	225	0.343	Worm
regulation of biosynthetic process	GO:0009889	250	0.337	Worm
single organism metabolic process	GO:0044710	217	0.317
protein metabolic process	GO:0019538	183	0.306
phosphate containing compound metabolic process	GO:0006796	108	0.298
phosphorus metabolic process	GO:0006793	109	0.290
muscle cell differentiation	GO:0042692	139	0.287
regulation of cellular biosynthetic process	GO:0031326	245	0.278	Worm
ribonucleotide metabolic process	GO:0009259	27	0.278
regulation of rna biosynthetic process	GO:2001141	213	0.274	Worm
tube morphogenesis	GO:0035239	349	0.273
regulation of cell development	GO:0060284	100	0.273
response to endogenous stimulus	GO:0009719	83	0.271
regulation of transcription dna templated	GO:0006355	213	0.269	Worm
central nervous system development	GO:0007417	387	0.265
cell motility	GO:0048870	244	0.261
muscle structure development	GO:0061061	196	0.259
regulation of nervous system development	GO:0051960	90	0.259
single organism reproductive process	GO:0044702	40	0.258
single organism localization	GO:1902578	225	0.258
protein modification process	GO:0036211	100	0.249
regulation of protein complex assembly	GO:0043254	3	0.248
muscle tissue development	GO:0060537	110	0.248
sensory organ development	GO:0007423	393	0.247	Zebrafish
anterior posterior pattern specification	GO:0009952	152	0.246	Zebrafish
nucleotide metabolic process	GO:0009117	28	0.245
positive regulation of transport	GO:0051050	2	0.241
regulation of phosphate metabolic process	GO:0019220	43	0.237
cellular macromolecular complex assembly	GO:0034622	24	0.235
negative regulation of muscle tissue development	GO:1901862	2	0.230
regulation of nitrogen compound metabolic process	GO:0051171	251	0.228	Worm
response to glucocorticoid	GO:0051384	1	0.222
regulation of cellular protein metabolic process	GO:0032268	52	0.218
purine containing compound metabolic process	GO:0072521	29	0.218
meiotic nuclear division	GO:0007126	4	0.213
organophosphate biosynthetic process	GO:0090407	23	0.209
fatty acid biosynthetic process	GO:0006633	4	0.208
ribonucleotide biosynthetic process	GO:0009260	20	0.207
ribose phosphate metabolic process	GO:0019693	27	0.202
response to drug	GO:0042493	3	0.202
gastrulation	GO:0007369	208	0.200
small molecule metabolic process	GO:0044281	77	0.195
phosphorylation	GO:0016310	69	0.190
nucleotide biosynthetic process	GO:0009165	21	0.187
cellular component morphogenesis	GO:0032989	336	0.187
transcription from rna polymerase ii promoter	GO:0006366	80	0.183	Worm
cellular response to chemical stimulus	GO:0070887	157	0.182
establishment of localization	GO:0051234	244	0.178
response to organic substance	GO:0010033	153	0.174
larval development	GO:0002164	2	0.170	Worm
phagocytosis	GO:0006909	3	0.169
striated muscle tissue development	GO:0014706	110	0.169
regulation of nucleic acid templated transcription	GO:1903506	213	0.164	Worm
positive regulation of biological process	GO:0048518	253	0.162	Worm
cell projection organization	GO:0030030	284	0.159
regulation of phosphorus metabolic process	GO:0051174	43	0.156
cellular response to organic substance	GO:0071310	105	0.156
regionalization	GO:0003002	274	0.155	Zebrafish
nucleic acid metabolic process	GO:0090304	244	0.154	Worm
myeloid cell differentiation	GO:0030099	86	0.150
ion transmembrane transport	GO:0034220	91	0.145
positive regulation of cellular process	GO:0048522	201	0.143	Worm
localization of cell	GO:0051674	244	0.142
cellular component biogenesis	GO:0044085	178	0.142
regulation of cell differentiation	GO:0045595	142	0.140
regulation of cell communication	GO:0010646	232	0.139
cellular protein metabolic process	GO:0044267	129	0.135
regulation of biological quality	GO:0065008	263	0.133
regulation of transcription from rna polymerase ii promoter in response to stress	GO:0043618	0	0.132
regulation of cellular ketone metabolic process	GO:0010565	7	0.132
regulation of cellular metabolic process	GO:0031323	320	0.132	Worm
muscle fiber development	GO:0048747	52	0.128
negative regulation of metabolic process	GO:0009892	86	0.128
growth	GO:0040007	174	0.127
head development	GO:0060322	303	0.127
positive regulation of phosphorus metabolic process	GO:0010562	21	0.125
embryonic organ development	GO:0048568	381	0.125
hemopoiesis	GO:0030097	183	0.123
regulation of response to stimulus	GO:0048583	269	0.121	Worm
regulation of cellular component organization	GO:0051128	86	0.120
urogenital system development	GO:0001655	97	0.120
positive regulation of multicellular organismal process	GO:0051240	52	0.118
cyclic nucleotide metabolic process	GO:0009187	18	0.117
multi organism reproductive process	GO:0044703	36	0.116
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	16	0.115
organophosphate metabolic process	GO:0019637	37	0.111
regulation of transmembrane transport	GO:0034762	18	0.110
striated muscle cell development	GO:0055002	108	0.110
immune system development	GO:0002520	191	0.109
multi organism process	GO:0051704	134	0.109	Worm
androgen metabolic process	GO:0008209	2	0.107
positive regulation of biosynthetic process	GO:0009891	68	0.106	Worm
embryonic organ morphogenesis	GO:0048562	274	0.104
protein complex assembly	GO:0006461	30	0.104
positive regulation of catabolic process	GO:0009896	4	0.104
negative regulation of multicellular organismal process	GO:0051241	69	0.103
protein complex biogenesis	GO:0070271	30	0.102
negative regulation of gene expression	GO:0010629	65	0.102
regulation of muscle tissue development	GO:1901861	6	0.101
protein complex subunit organization	GO:0071822	46	0.100
transmission of nerve impulse	GO:0019226	19	0.099
cellular response to hormone stimulus	GO:0032870	39	0.098
response to hormone	GO:0009725	48	0.095
regulation of catalytic activity	GO:0050790	55	0.094
regulation of hormone secretion	GO:0046883	2	0.094
inositol lipid mediated signaling	GO:0048017	2	0.093
mitochondrion organization	GO:0007005	4	0.092
single organism organelle organization	GO:1902589	199	0.091
cellular ketone metabolic process	GO:0042180	11	0.090
cellular response to estradiol stimulus	GO:0071392	1	0.090
negative regulation of feeding behavior	GO:2000252	2	0.089
regulation of growth	GO:0040008	42	0.088
positive regulation of cellular catabolic process	GO:0031331	3	0.087
nucleoside phosphate biosynthetic process	GO:1901293	21	0.085
otolith development	GO:0048840	32	0.085	Zebrafish
regulation of dna templated transcription in response to stress	GO:0043620	0	0.083
regulation of cellular amine metabolic process	GO:0033238	0	0.083
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.083	Worm
erythrocyte homeostasis	GO:0034101	55	0.082
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	68	0.082
myeloid cell homeostasis	GO:0002262	56	0.081
regulation of protein metabolic process	GO:0051246	56	0.080
steroid hormone mediated signaling pathway	GO:0043401	9	0.079
regulation of cell proliferation	GO:0042127	37	0.079
positive regulation of nucleic acid templated transcription	GO:1903508	57	0.077	Worm
myotube differentiation	GO:0014902	45	0.076
response to salt stress	GO:0009651	10	0.076
negative regulation of neurogenesis	GO:0050768	20	0.076
cellular response to endogenous stimulus	GO:0071495	68	0.073
negative regulation of nucleobase containing compound metabolic process	GO:0045934	59	0.073
single organism biosynthetic process	GO:0044711	71	0.072
cytoskeleton organization	GO:0007010	96	0.071
response to lipid	GO:0033993	60	0.070
mapk cascade	GO:0000165	18	0.070
organonitrogen compound metabolic process	GO:1901564	74	0.068
cellular response to organic cyclic compound	GO:0071407	38	0.067
peptidyl lysine methylation	GO:0018022	3	0.067
neuron differentiation	GO:0030182	353	0.067
defense response to other organism	GO:0098542	33	0.066	Worm
system process	GO:0003008	185	0.066
regulation of localization	GO:0032879	104	0.066
stem cell proliferation	GO:0072089	4	0.065
regulation of receptor activity	GO:0010469	2	0.064
erythrocyte development	GO:0048821	24	0.064
negative regulation of cell differentiation	GO:0045596	46	0.064
cellular response to nitrogen compound	GO:1901699	6	0.063
rna biosynthetic process	GO:0032774	181	0.063	Worm
cyclic purine nucleotide metabolic process	GO:0052652	18	0.063
hematopoietic or lymphoid organ development	GO:0048534	191	0.062
response to growth factor	GO:0070848	39	0.062
cell part morphogenesis	GO:0032990	246	0.062
positive regulation of cell cycle	GO:0045787	3	0.061
single organism transport	GO:0044765	206	0.061
cellular response to steroid hormone stimulus	GO:0071383	31	0.061
regulation of heart growth	GO:0060420	2	0.060
cyclic nucleotide biosynthetic process	GO:0009190	18	0.060
cell migration	GO:0016477	237	0.060
ion transport	GO:0006811	114	0.060
intracellular signal transduction	GO:0035556	85	0.059
monocarboxylic acid biosynthetic process	GO:0072330	12	0.059
purine ribonucleotide biosynthetic process	GO:0009152	20	0.058
regulation of neurogenesis	GO:0050767	87	0.058
positive regulation of transcription dna templated	GO:0045893	57	0.057	Worm
positive regulation of secretion	GO:0051047	1	0.057
oxoacid metabolic process	GO:0043436	31	0.057
cellular response to growth factor stimulus	GO:0071363	39	0.056
macromolecule modification	GO:0043412	111	0.055
blood vessel development	GO:0001568	246	0.055
cellular localization	GO:0051641	97	0.055
eye development	GO:0001654	277	0.054
signal transduction	GO:0007165	455	0.054
digestive tract development	GO:0048565	265	0.054
positive regulation of protein complex assembly	GO:0031334	2	0.053
aging	GO:0007568	2	0.052
skeletal system development	GO:0001501	181	0.052
muscle cell development	GO:0055001	115	0.052
digestive system development	GO:0055123	289	0.051
regulation of molecular function	GO:0065009	70	0.051
regulation of signaling	GO:0023051	235	0.051
macromolecule biosynthetic process	GO:0009059	227	0.050	Worm
positive regulation of gene expression	GO:0010628	71	0.050	Worm
epithelial cell differentiation	GO:0030855	116	0.050
reproduction	GO:0000003	40	0.050
actin filament based process	GO:0030029	64	0.049
negative regulation of innate immune response	GO:0045824	2	0.049
intracellular estrogen receptor signaling pathway	GO:0030520	3	0.049
response to oxygen containing compound	GO:1901700	55	0.048
erythrocyte differentiation	GO:0030218	54	0.048
negative regulation of blood circulation	GO:1903523	2	0.048
developmental growth	GO:0048589	166	0.047
lipid biosynthetic process	GO:0008610	22	0.047
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	42	0.047
signal transduction by phosphorylation	GO:0023014	18	0.046
regulation of innate immune response	GO:0045088	11	0.046
skeletal muscle organ development	GO:0060538	78	0.046
cellular protein modification process	GO:0006464	100	0.046
negative regulation of cell proliferation	GO:0008285	8	0.046
organic acid metabolic process	GO:0006082	31	0.046
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	3	0.045
protein polymerization	GO:0051258	4	0.045
adrenergic receptor signaling pathway	GO:0071875	5	0.045
dicarboxylic acid transport	GO:0006835	1	0.045
multicellular organismal signaling	GO:0035637	22	0.043
positive regulation of nucleobase containing compound metabolic process	GO:0045935	69	0.043	Worm
homeostatic process	GO:0042592	142	0.043
muscle organ development	GO:0007517	101	0.043
multicellular organismal reproductive process	GO:0048609	35	0.043
skeletal muscle fiber development	GO:0048741	35	0.043
organic acid transport	GO:0015849	9	0.043
behavior	GO:0007610	74	0.043	Worm
developmental maturation	GO:0021700	34	0.042
protein phosphorylation	GO:0006468	47	0.042
positive regulation of signaling	GO:0023056	56	0.042
amino acid transport	GO:0006865	2	0.042
negative regulation of signal transduction	GO:0009968	94	0.042
cellular macromolecule biosynthetic process	GO:0034645	224	0.042	Worm
regulation of muscle organ development	GO:0048634	9	0.041
ribose phosphate biosynthetic process	GO:0046390	20	0.041
positive regulation of protein metabolic process	GO:0051247	23	0.041
regulation of reproductive process	GO:2000241	4	0.041
feeding behavior	GO:0007631	5	0.041	Worm
response to wounding	GO:0009611	116	0.040
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	22	0.040	Worm
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.039
multicellular organism growth	GO:0035264	4	0.039
negative regulation of striated muscle tissue development	GO:0045843	2	0.039
organic anion transport	GO:0015711	15	0.039
digestive tract morphogenesis	GO:0048546	231	0.039
cell cell signaling	GO:0007267	52	0.039
cytokinesis	GO:0000910	3	0.038
cellular response to drug	GO:0035690	1	0.037
regulation of transport	GO:0051049	45	0.037
determination of heart left right asymmetry	GO:0061371	117	0.037
response to unfolded protein	GO:0006986	2	0.037
blood circulation	GO:0008015	87	0.037
organelle organization	GO:0006996	227	0.037
skeletal muscle tissue development	GO:0007519	67	0.037
negative regulation of cellular metabolic process	GO:0031324	77	0.037
cell recognition	GO:0008037	19	0.037
taxis	GO:0042330	109	0.037
negative regulation of nitrogen compound metabolic process	GO:0051172	59	0.036
regulation of cellular carbohydrate metabolic process	GO:0010675	4	0.036
defense response to bacterium	GO:0042742	22	0.036	Worm
regulation of developmental process	GO:0050793	247	0.036
action potential	GO:0001508	19	0.036
pigmentation	GO:0043473	85	0.035
negative regulation of cell development	GO:0010721	26	0.035
carboxylic acid metabolic process	GO:0019752	22	0.035
response to alkaloid	GO:0043279	2	0.035
establishment of localization in cell	GO:0051649	77	0.035
cell proliferation	GO:0008283	80	0.034
camera type eye development	GO:0043010	222	0.034
transport	GO:0006810	220	0.034
cellular response to lipid	GO:0071396	39	0.034
mitotic cell cycle	GO:0000278	64	0.033
negative regulation of biological process	GO:0048519	304	0.033
response to monosaccharide	GO:0034284	3	0.033
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	48	0.032
positive regulation of phosphate metabolic process	GO:0045937	21	0.032
regulation of nucleotide metabolic process	GO:0006140	17	0.032
homeostasis of number of cells	GO:0048872	62	0.031
cellular component assembly involved in morphogenesis	GO:0010927	107	0.031
metal ion transport	GO:0030001	58	0.031
organic substance transport	GO:0071702	58	0.031
stem cell differentiation	GO:0048863	117	0.030
cellular response to nutrient levels	GO:0031669	2	0.030
purine containing compound biosynthetic process	GO:0072522	20	0.030
regulation of cellular amino acid metabolic process	GO:0006521	0	0.030
enzyme linked receptor protein signaling pathway	GO:0007167	106	0.030
autophagy	GO:0006914	4	0.030
positive regulation of molecular function	GO:0044093	33	0.030
smad protein complex assembly	GO:0007183	1	0.030
female gonad development	GO:0008585	4	0.029
response to oxidative stress	GO:0006979	11	0.029
regulation of fatty acid metabolic process	GO:0019217	1	0.029
neuron projection morphogenesis	GO:0048812	161	0.028
connective tissue development	GO:0061448	99	0.028
regulation of dendrite development	GO:0050773	3	0.028
reactive oxygen species biosynthetic process	GO:1903409	1	0.028
positive regulation of cellular protein metabolic process	GO:0032270	22	0.028
regulation of response to nutrient levels	GO:0032107	1	0.028
brain development	GO:0007420	293	0.027
neuronal action potential	GO:0019228	18	0.027
regulation of signal transduction	GO:0009966	225	0.027
regulation of nucleoside metabolic process	GO:0009118	2	0.027
myotube cell development	GO:0014904	35	0.027
foregut morphogenesis	GO:0007440	4	0.027
regulation of carbohydrate metabolic process	GO:0006109	4	0.027
cellular response to oxygen levels	GO:0071453	1	0.027
cellular lipid metabolic process	GO:0044255	36	0.026
regulation of skeletal muscle tissue development	GO:0048641	4	0.026
camp biosynthetic process	GO:0006171	11	0.026
multicellular organism reproduction	GO:0032504	35	0.026
hormone biosynthetic process	GO:0042446	3	0.026
regulation of striated muscle tissue development	GO:0016202	6	0.026
amine metabolic process	GO:0009308	2	0.026
oligodendrocyte differentiation	GO:0048709	23	0.025
apoptotic process involved in development	GO:1902742	2	0.025
cell morphogenesis involved in differentiation	GO:0000904	195	0.025
blood vessel morphogenesis	GO:0048514	216	0.025
regulation of multicellular organismal process	GO:0051239	277	0.025
wnt signaling pathway	GO:0016055	80	0.025
synaptic transmission	GO:0007268	35	0.025
mononuclear cell proliferation	GO:0032943	1	0.025
heart development	GO:0007507	313	0.025
macromolecule localization	GO:0033036	54	0.025
epithelial tube morphogenesis	GO:0060562	148	0.024
nuclear division	GO:0000280	23	0.024
regulation of phosphorylation	GO:0042325	26	0.024
regulation of purine nucleotide catabolic process	GO:0033121	2	0.024
regulation of mapk cascade	GO:0043408	14	0.024
developmental process involved in reproduction	GO:0003006	27	0.024
macromolecular complex assembly	GO:0065003	35	0.024
intracellular steroid hormone receptor signaling pathway	GO:0030518	5	0.024
regulation of gtpase activity	GO:0043087	2	0.024
actin cytoskeleton organization	GO:0030036	63	0.024
vasculature development	GO:0001944	278	0.024
regulation of protein ubiquitination	GO:0031396	3	0.024
negative regulation of macromolecule biosynthetic process	GO:0010558	48	0.023
death	GO:0016265	121	0.023
response to hexose	GO:0009746	3	0.023
positive regulation of rna biosynthetic process	GO:1902680	57	0.023	Worm
posterior lateral line development	GO:0048916	38	0.023
regulation of growth rate	GO:0040009	1	0.023
camp metabolic process	GO:0046058	11	0.022
phagocytosis engulfment	GO:0006911	1	0.022
regulation of protein phosphorylation	GO:0001932	18	0.022
sensory organ morphogenesis	GO:0090596	200	0.022
cell projection assembly	GO:0030031	64	0.022
regulation of multicellular organism growth	GO:0040014	4	0.021
organic acid biosynthetic process	GO:0016053	12	0.021
regulation of tube size	GO:0035150	2	0.021
cellular amine metabolic process	GO:0044106	2	0.021
chondrocyte intercalation involved in growth plate cartilage morphogenesis	GO:0003428	1	0.021
response to acid chemical	GO:0001101	17	0.021
negative regulation of signaling	GO:0023057	96	0.021
positive regulation of catalytic activity	GO:0043085	25	0.021
macromolecular complex subunit organization	GO:0043933	74	0.021
regulation of autophagy	GO:0010506	3	0.020
reactive nitrogen species metabolic process	GO:2001057	0	0.020
neuroblast proliferation	GO:0007405	2	0.020
regulation of stem cell proliferation	GO:0072091	2	0.020
negative regulation of biosynthetic process	GO:0009890	55	0.020
nitric oxide biosynthetic process	GO:0006809	2	0.020
reproductive process	GO:0022414	40	0.019
lateral line system development	GO:0048925	76	0.019
inorganic ion transmembrane transport	GO:0098660	57	0.019
negative regulation of cellular protein metabolic process	GO:0032269	16	0.019
embryonic heart tube morphogenesis	GO:0003143	108	0.019
mitotic cell cycle process	GO:1903047	48	0.019
organelle localization	GO:0051640	49	0.019
neurotransmitter secretion	GO:0007269	2	0.019
regulation of protein modification process	GO:0031399	29	0.019
regulation of neural precursor cell proliferation	GO:2000177	3	0.019
cellular response to decreased oxygen levels	GO:0036294	1	0.019
medial fin development	GO:0033338	16	0.018
negative regulation of catabolic process	GO:0009895	3	0.018
cell cycle g1 s phase transition	GO:0044843	1	0.018
negative regulation of nucleic acid templated transcription	GO:1903507	45	0.018
carboxylic acid transport	GO:0046942	8	0.018
positive regulation of cellular amine metabolic process	GO:0033240	0	0.018
steroid hormone secretion	GO:0035929	1	0.018
organic cyclic compound catabolic process	GO:1901361	15	0.018
positive regulation of rna metabolic process	GO:0051254	59	0.018	Worm
cardiac muscle cell differentiation	GO:0055007	30	0.018
chemotaxis	GO:0006935	104	0.018
apoptotic process	GO:0006915	116	0.018
chordate embryonic development	GO:0043009	271	0.018
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	2	0.017
chemical homeostasis	GO:0048878	49	0.017
retina development in camera type eye	GO:0060041	146	0.017
regulation of protein modification by small protein conjugation or removal	GO:1903320	3	0.017
determination of left right symmetry	GO:0007368	179	0.017
generation of neurons	GO:0048699	385	0.017
cardiac muscle cell development	GO:0055013	20	0.017
positive regulation of secretion by cell	GO:1903532	1	0.017
negative regulation of protein phosphorylation	GO:0001933	4	0.017
cellular component movement	GO:0006928	335	0.017
regulation of cell migration	GO:0030334	40	0.017
regulation of intracellular signal transduction	GO:1902531	57	0.017
cation transport	GO:0006812	81	0.017
regulation of kinase activity	GO:0043549	15	0.016
gtp metabolic process	GO:0046039	4	0.016
cellular response to stress	GO:0033554	62	0.016
nucleobase containing small molecule metabolic process	GO:0055086	32	0.016
phospholipase c activating g protein coupled receptor signaling pathway	GO:0007200	2	0.016
regulation of dna templated transcription elongation	GO:0032784	3	0.016
regulation of apoptotic process	GO:0042981	98	0.016
negative regulation of kinase activity	GO:0033673	4	0.016
negative regulation of defense response	GO:0031348	2	0.016
regulation of purine nucleotide metabolic process	GO:1900542	17	0.016
regulation of cell motility	GO:2000145	46	0.016
neuron neuron synaptic transmission	GO:0007270	1	0.016
positive regulation of reproductive process	GO:2000243	2	0.016
sensory system development	GO:0048880	76	0.015
generation of precursor metabolites and energy	GO:0006091	5	0.015
inorganic cation transmembrane transport	GO:0098662	50	0.015
response to activity	GO:0014823	14	0.015
response to nicotine	GO:0035094	2	0.015
ovulation cycle process	GO:0022602	2	0.015
positive regulation of cellular biosynthetic process	GO:0031328	68	0.015	Worm
locomotory behavior	GO:0007626	34	0.015
regulation of blood pressure	GO:0008217	1	0.015
negative regulation of camp biosynthetic process	GO:0030818	7	0.015
heart morphogenesis	GO:0003007	156	0.015
cardiocyte differentiation	GO:0035051	44	0.015
kidney vasculature development	GO:0061440	2	0.015
regulation of synapse organization	GO:0050807	3	0.015
cell cycle	GO:0007049	93	0.015
ovarian follicle development	GO:0001541	2	0.015
cation transmembrane transport	GO:0098655	65	0.015
regulation of system process	GO:0044057	40	0.015
cell division	GO:0051301	20	0.014
positive regulation of lipid metabolic process	GO:0045834	1	0.014
positive regulation of wound healing	GO:0090303	1	0.014
stem cell division	GO:0017145	1	0.014
response to vitamin b3	GO:0033552	2	0.014
anion transport	GO:0006820	38	0.014
neurotransmitter transport	GO:0006836	2	0.014
energy reserve metabolic process	GO:0006112	2	0.014
histone modification	GO:0016570	20	0.014
regulation of developmental growth	GO:0048638	38	0.014
gamma aminobutyric acid signaling pathway	GO:0007214	1	0.014
morphogenesis of an epithelium	GO:0002009	333	0.014
response to organonitrogen compound	GO:0010243	12	0.014
regulation of programmed cell death	GO:0043067	101	0.014
regulation of postsynaptic membrane potential	GO:0060078	1	0.014
regulation of cell death	GO:0010941	103	0.014
mesoderm development	GO:0007498	88	0.014
establishment of organelle localization	GO:0051656	45	0.014
regulation of response to extracellular stimulus	GO:0032104	1	0.014
cellular homeostasis	GO:0019725	26	0.014
heart looping	GO:0001947	94	0.014
positive regulation of cell communication	GO:0010647	56	0.013
negative regulation of cellular biosynthetic process	GO:0031327	55	0.013
calcium ion import	GO:0070509	4	0.013
somite development	GO:0061053	96	0.013
response to metal ion	GO:0010038	34	0.013
response to estrogen	GO:0043627	27	0.013
regulation of immune system process	GO:0002682	34	0.013
peptide transport	GO:0015833	1	0.013
dorsal ventral pattern formation	GO:0009953	125	0.013
response to inorganic substance	GO:0010035	38	0.013
positive regulation of muscle tissue development	GO:1901863	1	0.013

mstnb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.234
nervous system disease	DOID:863	0.111
musculoskeletal system disease	DOID:17	0.023
disease of mental health	DOID:150	0.014

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