Danio rerio

9 known processes

upf2

UPF2 regulator of nonsense transcripts homolog (yeast)

upf2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.702
mrna catabolic processGO:000640260.131
rna catabolic processGO:000640170.106
mrna metabolic processGO:0016071200.104
nuclear transcribed mrna catabolic processGO:000095640.091
cellular nitrogen compound metabolic processGO:00346412900.091
cellular macromolecule metabolic processGO:00442603910.085
agingGO:000756820.083
larval developmentGO:000216420.080
nitrogen compound metabolic processGO:00068073190.074
organic cyclic compound metabolic processGO:19013603010.072
cellular aromatic compound metabolic processGO:00067252950.069
heterocycle metabolic processGO:00464832900.059
peptidyl serine phosphorylationGO:001810510.059
gtp metabolic processGO:004603940.058
rna metabolic processGO:00160702190.057
positive regulation of transportGO:005105020.056
nucleic acid metabolic processGO:00903042440.052
peptidyl serine modificationGO:001820920.046
nucleobase containing compound metabolic processGO:00061392740.046
regulation of nucleotide catabolic processGO:003081120.044
single fertilizationGO:000733830.039
guanosine containing compound metabolic processGO:190106840.039
positive regulation of translationGO:004572710.038
guanosine containing compound catabolic processGO:190106920.038
synaptic growth at neuromuscular junctionGO:005112420.037
nucleoside monophosphate catabolic processGO:000912540.036
translational initiationGO:000641330.033
fertilizationGO:000956630.033
multicellular organism growthGO:003526440.033
cellular catabolic processGO:0044248270.032
purine ribonucleoside monophosphate catabolic processGO:000916940.032
negative regulation of protein phosphorylationGO:000193340.031
regulation of synapse organizationGO:005080730.031
small molecule metabolic processGO:0044281770.031
amine metabolic processGO:000930820.031
phagocytosisGO:000690930.030
gene expressionGO:00104672520.030
regulation of purine nucleotide catabolic processGO:003312120.029
regulation of synaptic growth at neuromuscular junctionGO:000858210.029
regulation of gtp catabolic processGO:003312420.029
gtp catabolic processGO:000618420.029
regulation of reproductive processGO:200024140.028
regulation of cellular amino acid metabolic processGO:000652100.028
heterocycle catabolic processGO:0046700150.028
cellular macromolecule catabolic processGO:0044265120.028
cellular macromolecule biosynthetic processGO:00346452240.028
cellular response to lipopolysaccharideGO:007122230.028
regulation of synapse assemblyGO:005196330.028
lipid storageGO:001991510.028
maintenance of locationGO:005123540.028
stem cell maintenanceGO:001982740.028
organic substance biosynthetic processGO:19015762890.028
single organism metabolic processGO:00447102170.028
atp catabolic processGO:000620040.027
regulation of nucleoside metabolic processGO:000911820.027
positive regulation of cellular catabolic processGO:003133130.027
regulation of cellular ketone metabolic processGO:001056570.027
protein localization to nucleusGO:003450430.027
autophagyGO:000691440.027
modification dependent protein catabolic processGO:001994130.027
locomotionGO:00400113130.027
regulation of macromolecule metabolic processGO:00602553170.026
eye developmentGO:00016542770.026
regionalizationGO:00030022740.026
cellular component disassemblyGO:002241110.026
biosynthetic processGO:00090582940.026
regulation of cellular metabolic processGO:00313233200.026
symbiosis encompassing mutualism through parasitismGO:004440340.025
positive regulation of cellular amino acid metabolic processGO:004576400.025
cellular amine metabolic processGO:004410620.025
cellular nitrogen compound catabolic processGO:0044270150.025
regulation of metabolic processGO:00192223590.025
cellular response to external stimulusGO:007149620.025
rna localizationGO:000640340.025
meiotic nuclear divisionGO:000712640.025
positive regulation of secretion by cellGO:190353210.024
negative regulation of protein kinase activityGO:000646940.024
aromatic compound catabolic processGO:0019439150.024
cellular protein catabolic processGO:004425740.024
ribonucleoside monophosphate catabolic processGO:000915840.024
nuclear migrationGO:000709730.024
regulation of cellular amine metabolic processGO:003323800.023
macromolecule biosynthetic processGO:00090592270.023
response to carbohydrateGO:000974330.023
sensory organ developmentGO:00074233930.023
positive regulation of purine nucleotide catabolic processGO:003312310.023
negative regulation of nuclear divisionGO:005178430.023
cellular response to nutrient levelsGO:003166920.023
negative regulation of biological processGO:00485193040.023
regulation of gene expressionGO:00104682650.023
cellular ketone metabolic processGO:0042180110.023
modification dependent macromolecule catabolic processGO:004363230.023
positive regulation of cellular amine metabolic processGO:003324000.023
camera type eye developmentGO:00430102220.023
cellular component movementGO:00069283350.023
negative regulation of cellular catabolic processGO:003133030.023
interspecies interaction between organismsGO:004441940.023
regulation of bindingGO:005109830.022
organic cyclic compound catabolic processGO:1901361150.022
carboxylic acid metabolic processGO:0019752220.022
positive regulation of cell cycleGO:004578730.022
cellular amino acid metabolic processGO:000652070.022
response to chemicalGO:00422213200.022
retina development in camera type eyeGO:00600411460.022
signal transduction in absence of ligandGO:003803410.022
negative regulation of catabolic processGO:000989530.022
regulation of primary metabolic processGO:00800903110.022
negative regulation of kinase activityGO:003367340.022
macromolecular complex disassemblyGO:003298410.022
regulation of cell activationGO:005086510.021
proteolysis involved in cellular protein catabolic processGO:005160330.021
positive regulation of catabolic processGO:000989640.021
negative regulation of map kinase activityGO:004340720.021
regulation of stem cell differentiationGO:200073640.021
negative regulation of protein serine threonine kinase activityGO:007190120.021
oxoacid metabolic processGO:0043436310.021
response to corticosteroidGO:003196010.021
regulation of protein catabolic processGO:004217610.021
carboxylic acid catabolic processGO:004639530.021
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.021
endosomal transportGO:001619720.021
transportGO:00068102200.020
organic acid metabolic processGO:0006082310.020
apoptotic process involved in developmentGO:190274220.020
hormone secretionGO:004687920.020
stem cell proliferationGO:007208940.020
ubiquitin dependent protein catabolic processGO:000651130.020
central nervous system developmentGO:00074173870.020
regulation of dendrite developmentGO:005077330.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
negative regulation of stem cell differentiationGO:200073720.020
establishment of localizationGO:00512342440.019
peptidyl threonine phosphorylationGO:001810710.019
regulation of establishment of protein localizationGO:007020140.019
response to glucoseGO:000974930.019
protein localization to plasma membraneGO:007265910.019
neurotransmitter transportGO:000683620.019
establishment of protein localization to organelleGO:007259440.019
multi organism cellular processGO:004476420.019
establishment of rna localizationGO:005123630.019
regulation of hormone secretionGO:004688320.019
regulation of cellular macromolecule biosynthetic processGO:20001122220.019
response to uvGO:000941130.019
cellular biosynthetic processGO:00442492860.019
viral processGO:001603210.019
nucleic acid transportGO:005065720.019
specification of symmetryGO:00097992040.019
regulation of gtpase activityGO:004308720.019
response to monosaccharideGO:003428430.019
endothelial cell fate commitmentGO:006083930.019
morphogenesis of an epitheliumGO:00020093330.019
brain developmentGO:00074202930.019
rna transportGO:005065820.019
regulation of protein transportGO:005122330.019
protein stabilizationGO:005082120.018
nuclear transportGO:005116940.018
pathway restricted smad protein phosphorylationGO:006038910.018
regulation of protein complex assemblyGO:004325430.018
actin polymerization or depolymerizationGO:000815420.018
regulation of fatty acid metabolic processGO:001921710.018
cellular response to starvationGO:000926710.018
regulation of mrna processingGO:005068430.018
regulation of macromolecule biosynthetic processGO:00105562250.018
regulation of bone mineralizationGO:003050020.018
muscle structure developmentGO:00610611960.018
exocytosisGO:000688710.018
tube closureGO:006060610.018
single organism localizationGO:19025782250.018
transmission of nerve impulseGO:0019226190.018
heterocycle biosynthetic processGO:00181302150.018
signal transductionGO:00071654550.018
positive regulation of nucleoside metabolic processGO:004597910.018
nucleocytoplasmic transportGO:000691340.018
catabolic processGO:0009056320.018
regulation of biomineral tissue developmentGO:007016720.018
sensory perception of chemical stimulusGO:000760630.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
primary neural tube formationGO:001402010.018
response to hexoseGO:000974630.018
meiotic cell cycle processGO:190304630.017
regulation of intracellular protein transportGO:003315730.017
organelle fusionGO:004828430.017
post embryonic organ developmentGO:004856940.017
cell projection morphogenesisGO:00488582440.017
secondary metabolic processGO:001974830.017
developmental programmed cell deathGO:001062340.017
peptide transportGO:001583310.017
regulation of neurotransmitter transportGO:005158810.017
cellular response to extracellular stimulusGO:003166820.017
cell substrate adhesionGO:003158940.017
nephron morphogenesisGO:007202820.017
oocyte maturationGO:000155640.017
b cell activationGO:004211320.017
somatic stem cell maintenanceGO:003501910.017
regulation of autophagyGO:001050630.017
regulation of neurotransmitter secretionGO:004692810.017
centrosome organizationGO:005129710.017
extrinsic apoptotic signaling pathwayGO:009719130.017
organonitrogen compound metabolic processGO:1901564740.017
head developmentGO:00603223030.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
determination of left right symmetryGO:00073681790.017
transcription dna templatedGO:00063511810.017
regulation of synaptic plasticityGO:004816710.017
embryonic organ developmentGO:00485683810.017
determination of bilateral symmetryGO:00098552040.017
transmembrane transportGO:00550851200.016
chordate embryonic developmentGO:00430092710.016
regulation of developmental processGO:00507932470.016
protein metabolic processGO:00195381830.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
protein dephosphorylationGO:000647030.016
eye morphogenesisGO:00485921440.016
cell projection organizationGO:00300302840.016
protein targeting to nucleusGO:004474430.016
regulation of cytokine productionGO:000181730.016
regulation of nitrogen compound metabolic processGO:00511712510.016
heart developmentGO:00075073130.016
positive regulation of gtp catabolic processGO:003312610.016
tube morphogenesisGO:00352393490.016
phosphate containing compound metabolic processGO:00067961080.016
regulation of cytoplasmic transportGO:190364940.016
hepaticobiliary system developmentGO:0061008980.016
membrane invaginationGO:001032410.016
vasculature developmentGO:00019442780.016
protein importGO:001703830.016
negative regulation of chromosome organizationGO:200125110.015
cellular protein modification processGO:00064641000.015
cellular response to oxygen levelsGO:007145310.015
dorsal ventral pattern formationGO:00099531250.015
regulation of mrna splicing via spliceosomeGO:004802430.015
ventricular cardiac muscle tissue morphogenesisGO:005501020.015
neuron differentiationGO:00301823530.015
proteasomal protein catabolic processGO:001049820.015
cellular response to molecule of bacterial originGO:007121930.015
compound eye developmentGO:004874920.015
regulation of protein ubiquitinationGO:003139630.015
positive regulation of cellular component biogenesisGO:004408930.015
microtubule organizing center organizationGO:003102310.015
lymph vessel developmentGO:0001945270.015
cellular component biogenesisGO:00440851780.015
nucleobase containing compound catabolic processGO:0034655150.015
embryonic organ morphogenesisGO:00485622740.015
cellular protein metabolic processGO:00442671290.015
multicellular organismal signalingGO:0035637220.015
amino acid transportGO:000686520.015
system processGO:00030081850.015
positive regulation of protein complex assemblyGO:003133420.015
positive regulation of secretionGO:005104710.015
macromolecule catabolic processGO:0009057150.015
cellular response to biotic stimulusGO:007121630.015
stem cell divisionGO:001714510.015
regulation of protein complex disassemblyGO:004324410.015
regulation of metal ion transportGO:001095940.015
cellular response to hypoxiaGO:007145610.015
apoptotic process involved in morphogenesisGO:006056120.015
protein complex disassemblyGO:004324110.015
localization of cellGO:00516742440.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
regulation of biological qualityGO:00650082630.015
adherens junction organizationGO:003433240.015
positive regulation of cytoskeleton organizationGO:005149530.015
purine nucleoside monophosphate catabolic processGO:000912840.015
response to drugGO:004249330.015
cellular component morphogenesisGO:00329893360.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
embryonic skeletal system developmentGO:0048706970.015
cell surface receptor signaling pathwayGO:00071663250.015
mitochondrion organizationGO:000700540.015
cytoplasm organizationGO:000702840.015
cell migrationGO:00164772370.015
embryo development ending in birth or egg hatchingGO:00097922710.015
glucose homeostasisGO:004259310.014
ventricular cardiac muscle tissue developmentGO:000322930.014
regulation of blood pressureGO:000821710.014
macroautophagyGO:001623610.014
positive regulation of immune effector processGO:000269930.014
embryonic skeletal joint developmentGO:007249830.014
golgi vesicle transportGO:004819330.014
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.014
rna 3 end processingGO:003112320.014
sensory organ morphogenesisGO:00905962000.014
generation of neuronsGO:00486993850.014
single organism membrane fusionGO:004480120.014
carbohydrate homeostasisGO:003350010.014
intracellular mrna localizationGO:000829810.014
negative regulation of mapk cascadeGO:004340940.014
single organism transportGO:00447652060.014
nucleic acid templated transcriptionGO:00976591810.014
positive regulation of nucleotide catabolic processGO:003081310.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
regulation of chromosome segregationGO:005198310.014
regulation of erythrocyte differentiationGO:004564620.014
regulation of cell shapeGO:000836010.014
adult behaviorGO:003053420.014
blood vessel developmentGO:00015682460.014
protein import into nucleusGO:000660630.013
regulation of cellular protein catabolic processGO:190336210.013
transcription from rna polymerase ii promoterGO:0006366800.013
digestive system developmentGO:00551232890.013
digestive tract developmentGO:00485652650.013
regulation of protein import into nucleusGO:004230620.013
neuroblast proliferationGO:000740520.013
mesenchyme developmentGO:00604851270.013
regulation of nucleocytoplasmic transportGO:004682220.013
regulation of organ growthGO:004662030.013
cellular response to retinoic acidGO:007130010.013
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.013
regulation of response to stimulusGO:00485832690.013
negative regulation of mitosisGO:004583930.013
maternal determination of anterior posterior axis embryoGO:000835840.013
regulation of protein bindingGO:004339330.013
spindle assembly involved in mitosisGO:009030710.013
nucleobase containing compound biosynthetic processGO:00346542050.013
single organism nuclear importGO:190259330.013
regulation of stem cell proliferationGO:007209120.013
muscle cell developmentGO:00550011150.013
female gonad developmentGO:000858540.013
tissue remodelingGO:004877140.013
gland developmentGO:00487321430.013
regulation of ion transmembrane transporter activityGO:003241220.013
endocrine processGO:005088620.013
somatic muscle developmentGO:000752540.013
regulation of transporter activityGO:003240920.013
regulation of transmembrane transporter activityGO:002289820.013
hormone transportGO:000991420.013
determination of heart left right asymmetryGO:00613711170.013
regulation of transcription dna templatedGO:00063552130.013
neurotransmitter secretionGO:000726920.013
regulation of multicellular organismal processGO:00512392770.013
nuclear importGO:005117030.013
phosphorus metabolic processGO:00067931090.013
protein polymerizationGO:005125840.013
small molecule catabolic processGO:004428230.013
phagocytosis engulfmentGO:000691110.013
protein complex localizationGO:003150310.013
membrane fusionGO:006102520.012
pole plasm assemblyGO:000731540.012
regulation of protein targetingGO:190353320.012
odontogenesis of dentin containing toothGO:004247510.012
mononuclear cell proliferationGO:003294310.012
positive regulation of myeloid cell differentiationGO:004563920.012
microtubule based processGO:0007017600.012
positive regulation of lymphocyte mediated immunityGO:000270810.012
regulation of translational initiationGO:000644610.012
pronuclear migrationGO:003504610.012
gastrulationGO:00073692080.012
cellular response to radiationGO:007147840.012
energy reserve metabolic processGO:000611220.012
regulation of reactive oxygen species metabolic processGO:200037720.012
actin filament polymerizationGO:003004120.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
positive regulation of synapse assemblyGO:005196510.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
regulation of epithelial cell proliferationGO:005067830.012
lipid metabolic processGO:0006629520.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
negative regulation of protein localization to nucleusGO:190018120.012
regulation of anatomical structure morphogenesisGO:00226031300.012
positive regulation of cell activationGO:005086710.012
regulation of sodium ion transportGO:000202820.012
striated muscle tissue developmentGO:00147061100.012
cellular component assemblyGO:00226071700.012
immunoglobulin mediated immune responseGO:001606430.012
regulation of jak stat cascadeGO:004642530.012
positive regulation of jak stat cascadeGO:004642720.012
i kappab kinase nf kappab signalingGO:000724940.012
heart morphogenesisGO:00030071560.012
regulation of signalingGO:00230512350.012
positive regulation of epithelial cell proliferationGO:005067910.012
protein acylationGO:004354330.012
aromatic compound biosynthetic processGO:00194382170.012
peptidyl threonine modificationGO:001821010.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
actin filament based movementGO:003004810.012
b cell mediated immunityGO:001972430.012
cellular response to decreased oxygen levelsGO:003629410.012
liver developmentGO:0001889960.012
lipid catabolic processGO:001604240.012
zymogen activationGO:003163830.011
protein homooligomerizationGO:005126030.011
protein modification processGO:00362111000.011
cytokinesisGO:000091030.011
single organism organelle organizationGO:19025891990.011
organelle organizationGO:00069962270.011
negative regulation of intracellular transportGO:003238730.011
alternative mrna splicing via spliceosomeGO:000038010.011
negative regulation of translationGO:001714810.011
ear developmentGO:00435831270.011
regulation of protein localization to nucleusGO:190018020.011
response to nutrientGO:000758430.011
female sex differentiationGO:004666040.011
action potentialGO:0001508190.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
type i interferon productionGO:003260620.011
negative regulation of cellular processGO:00485232830.011
regulation of membrane potentialGO:0042391230.011
lymphocyte proliferationGO:004665110.011
positive regulation of biological processGO:00485182530.011
cell part morphogenesisGO:00329902460.011
negative regulation of synapse assemblyGO:005196420.011
positive regulation of gtpase activityGO:004354710.011
regulation of signal transductionGO:00099662250.011
renal system developmentGO:0072001940.011
striated muscle cell differentiationGO:00511461290.011
germ line stem cell maintenanceGO:003071820.011
positive regulation of cytokine productionGO:000181920.011
negative regulation of reproductive processGO:200024230.011
mesenchymal cell differentiationGO:0048762870.011
meiotic chromosome segregationGO:004513230.011
negative regulation of cytokine productionGO:000181810.011
response to glucocorticoidGO:005138410.011
regulation of cellular component organizationGO:0051128860.011
histone deacetylationGO:001657520.011
posterior lateral line developmentGO:0048916380.011
cell morphogenesisGO:00009022890.011
nucleobase containing compound transportGO:001593120.011
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.011
anterior posterior pattern specificationGO:00099521520.011
rna biosynthetic processGO:00327741810.011
regulation of tube sizeGO:003515020.011
lipid oxidationGO:003444010.011
negative regulation of macromolecule metabolic processGO:0010605760.011
rna export from nucleusGO:000640510.011
ameboidal type cell migrationGO:00016671430.011
response to alkaloidGO:004327920.011
regulation of blood vessel sizeGO:005088020.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
regulation of multicellular organismal developmentGO:20000262230.011
positive regulation of cellular processGO:00485222010.011
spermatid developmentGO:000728620.011
negative regulation of multi organism processGO:004390130.011
leukocyte proliferationGO:007066110.011
production of molecular mediator of immune responseGO:000244020.011
cell matrix adhesionGO:000716040.011
astrocyte differentiationGO:004870810.011
regulation of multicellular organism growthGO:004001440.011
interaction with hostGO:005170140.011
regulation of cellular biosynthetic processGO:00313262450.011
negative regulation of gene expressionGO:0010629650.011
mitotic cell cycleGO:0000278640.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
peptidyl lysine acetylationGO:001839420.011
organic cyclic compound biosynthetic processGO:19013622230.011
mrna 3 end processingGO:003112420.011
nuclear exportGO:005116810.011
negative regulation of ras protein signal transductionGO:004658010.011
lymphangiogenesisGO:0001946250.010
cellular protein complex disassemblyGO:004362410.010
regulation of cell deathGO:00109411030.010
regulation of rna metabolic processGO:00512522240.010
regulation of biosynthetic processGO:00098892500.010
macromolecule modificationGO:00434121110.010
cilium morphogenesisGO:0060271850.010
monoamine transportGO:001584410.010
erk1 and erk2 cascadeGO:007037140.010
dicarboxylic acid transportGO:000683510.010
skeletal system morphogenesisGO:00487051020.010
smooth muscle tissue developmentGO:004874510.010
neuromuscular synaptic transmissionGO:000727420.010
protein acetylationGO:000647320.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
response to amineGO:001407510.010
developmental growthGO:00485891660.010
cell motilityGO:00488702440.010
antimicrobial humoral responseGO:001973020.010
protein targeting to membraneGO:000661210.010
positive regulation of protein polymerizationGO:003227320.010
regulation of endocrine processGO:004406020.010
blood vessel morphogenesisGO:00485142160.010
embryonic skeletal joint morphogenesisGO:006027230.010
positive regulation of neuron deathGO:190121610.010
positive regulation of multi organism processGO:004390230.010
negative regulation of leukocyte differentiationGO:190210610.010
organism emergence from protective structureGO:007168440.010

upf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
disease of metabolismDOID:001466700.030
musculoskeletal system diseaseDOID:1700.027
immune system diseaseDOID:291400.018
cardiovascular system diseaseDOID:128700.018
inherited metabolic disorderDOID:65500.017
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
muscular diseaseDOID:008000000.014
muscle tissue diseaseDOID:6600.013
organ system cancerDOID:005068600.013
myopathyDOID:42300.013
nervous system diseaseDOID:86300.011
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010
sensory system diseaseDOID:005015500.010
heart diseaseDOID:11400.010
cardiomyopathyDOID:005070000.010
intrinsic cardiomyopathyDOID:006003600.010