Danio rerio

18 known processes

LOC556647

GDNF family receptor alpha-4-like

LOC556647 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vasculature developmentGO:00019442780.240
cartilage developmentGO:0051216960.212
striated muscle cell differentiationGO:00511461290.200
connective tissue developmentGO:0061448990.185
cell surface receptor signaling pathwayGO:00071663250.157
response to stressGO:00069502630.140
synaptic target recognitionGO:000803910.140
muscle structure developmentGO:00610611960.135
immune system processGO:00023762410.131
organic cyclic compound biosynthetic processGO:19013622230.127
blood vessel morphogenesisGO:00485142160.127
skeletal system developmentGO:00015011810.122
embryonic organ developmentGO:00485683810.120
regulation of biosynthetic processGO:00098892500.109
regulation of cell proliferation involved in heart morphogenesisGO:200013620.109
embryonic organ morphogenesisGO:00485622740.108
embryonic skeletal system developmentGO:0048706970.104
blood vessel developmentGO:00015682460.102
cellular macromolecule metabolic processGO:00442603910.102
cartilage condensationGO:000150230.102
determination of bilateral symmetryGO:00098552040.099
cellular component morphogenesisGO:00329893360.096
aromatic compound biosynthetic processGO:00194382170.094
regulation of cellular macromolecule biosynthetic processGO:20001122220.091
signal transductionGO:00071654550.090
organic substance biosynthetic processGO:19015762890.088
regulation of multicellular organismal processGO:00512392770.083
sensory organ developmentGO:00074233930.082
regulation of response to stimulusGO:00485832690.077
regulation of epithelial cell proliferationGO:005067830.076
cellular nitrogen compound biosynthetic processGO:00442712180.075
generation of neuronsGO:00486993850.074
positive regulation of apoptotic signaling pathwayGO:200123510.074
organic cyclic compound metabolic processGO:19013603010.071
determination of dorsal ventral asymmetryGO:0048262340.071
cell morphogenesis involved in differentiationGO:00009041950.069
embryo development ending in birth or egg hatchingGO:00097922710.068
regulation of nucleic acid templated transcriptionGO:19035062130.068
enzyme linked receptor protein signaling pathwayGO:00071671060.068
retina development in camera type eyeGO:00600411460.067
organelle organizationGO:00069962270.067
kupffer s vesicle developmentGO:0070121500.067
nucleic acid metabolic processGO:00903042440.067
septum transversum developmentGO:000334340.066
cellular component movementGO:00069283350.065
cellular nitrogen compound metabolic processGO:00346412900.065
eye developmentGO:00016542770.064
immune system developmentGO:00025201910.063
embryonic skeletal system morphogenesisGO:0048704930.063
regulation of cell developmentGO:00602841000.062
nucleic acid templated transcriptionGO:00976591810.062
sensory organ morphogenesisGO:00905962000.061
morphogenesis of an epitheliumGO:00020093330.060
response to woundingGO:00096111160.058
macromolecule biosynthetic processGO:00090592270.058
embryonic cranial skeleton morphogenesisGO:0048701900.058
cellular biosynthetic processGO:00442492860.056
skeletal system morphogenesisGO:00487051020.054
muscle organ developmentGO:00075171010.054
angiogenesisGO:00015251580.054
eye morphogenesisGO:00485921440.053
muscle cell differentiationGO:00426921390.053
tube morphogenesisGO:00352393490.052
nucleobase containing compound biosynthetic processGO:00346542050.052
cell morphogenesisGO:00009022890.051
regulation of transcription dna templatedGO:00063552130.051
cellular response to external stimulusGO:007149620.051
stem cell proliferationGO:007208940.051
system processGO:00030081850.051
neural crest cell differentiationGO:0014033720.050
somatic stem cell maintenanceGO:003501910.050
muscle tissue developmentGO:00605371100.050
notochord developmentGO:0030903540.050
mesenchymal cell proliferationGO:001046310.050
regulation of cellular biosynthetic processGO:00313262450.049
negative regulation of biological processGO:00485193040.049
regulation of signal transductionGO:00099662250.049
camera type eye developmentGO:00430102220.049
biosynthetic processGO:00090582940.049
cellular aromatic compound metabolic processGO:00067252950.048
heart morphogenesisGO:00030071560.048
hematopoietic or lymphoid organ developmentGO:00485341910.047
agingGO:000756820.047
somatic muscle developmentGO:000752540.047
gene expressionGO:00104672520.046
regulation of multicellular organismal developmentGO:20000262230.046
regulation of macromolecule biosynthetic processGO:00105562250.045
nitrogen compound metabolic processGO:00068073190.045
regulation of reproductive processGO:200024140.045
response to chemicalGO:00422213200.045
retinal rod cell developmentGO:004654840.045
negative regulation of sequestering of calcium ionGO:005128340.044
cellular response to nutrient levelsGO:003166920.044
cell projection morphogenesisGO:00488582440.044
neuron developmentGO:00486662620.044
regulation of nervous system developmentGO:0051960900.043
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.043
wound healingGO:0042060900.042
proteasomal protein catabolic processGO:001049820.042
positive regulation of cell cycleGO:004578730.042
transcription dna templatedGO:00063511810.042
response to alkaloidGO:004327920.041
regulation of nitrogen compound metabolic processGO:00511712510.040
heterocycle metabolic processGO:00464832900.040
synaptic transmission cholinergicGO:000727140.039
stem cell maintenanceGO:001982740.039
digestive tract developmentGO:00485652650.039
regulation of signalingGO:00230512350.038
rna metabolic processGO:00160702190.038
regulation of cellular metabolic processGO:00313233200.038
regulation of developmental processGO:00507932470.038
chordate embryonic developmentGO:00430092710.038
inner ear developmentGO:00488391260.038
neuromuscular synaptic transmissionGO:000727420.037
cellular macromolecule biosynthetic processGO:00346452240.037
cellular response to stressGO:0033554620.037
maintenance of locationGO:005123540.037
regulation of primary metabolic processGO:00800903110.037
cellular response to starvationGO:000926710.036
cellular response to chemical stimulusGO:00708871570.036
single organism organelle organizationGO:19025891990.036
regulation of behaviorGO:0050795240.036
rna biosynthetic processGO:00327741810.036
fin developmentGO:0033333770.035
regulation of synapse assemblyGO:005196330.035
adult behaviorGO:003053420.034
digestive tract morphogenesisGO:00485462310.034
cellular response to extracellular stimulusGO:003166820.034
negative chemotaxisGO:005091910.034
locomotionGO:00400113130.034
regulation of gene expressionGO:00104682650.034
stem cell developmentGO:0048864820.034
regulation of skeletal muscle tissue developmentGO:004864140.033
ion transportGO:00068111140.033
regulation of protein catabolic processGO:004217610.032
regulation of proteolysisGO:0030162240.032
modification dependent protein catabolic processGO:001994130.032
neuron differentiationGO:00301823530.032
mesenchyme developmentGO:00604851270.032
regenerationGO:0031099910.032
regulation of metabolic processGO:00192223590.032
eye photoreceptor cell differentiationGO:0001754450.031
epithelial cell differentiationGO:00308551160.031
negative regulation of nucleic acid templated transcriptionGO:1903507450.031
extrinsic apoptotic signaling pathwayGO:009719130.031
meiotic nuclear divisionGO:000712640.031
striated muscle tissue developmentGO:00147061100.030
developmental growthGO:00485891660.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
modification dependent macromolecule catabolic processGO:004363230.030
b cell activationGO:004211320.029
organelle assemblyGO:00709251100.029
primary neural tube formationGO:001402010.029
nucleoside monophosphate catabolic processGO:000912540.029
regulation of axon extensionGO:0030516240.029
cartilage morphogenesisGO:0060536130.029
nucleobase containing compound metabolic processGO:00061392740.029
chondrocyte developmentGO:000206340.029
sequestering of metal ionGO:005123830.029
negative regulation of cellular processGO:00485232830.029
cellular protein catabolic processGO:004425740.029
regulation of biological qualityGO:00650082630.028
regulation of tube sizeGO:003515020.028
regulation of rna metabolic processGO:00512522240.028
regulation of macromolecule metabolic processGO:00602553170.028
mesenchymal cell differentiationGO:0048762870.027
regulation of cell activationGO:005086510.027
neuron projection developmentGO:00311751800.027
establishment of localizationGO:00512342440.026
regulation of wound healingGO:006104120.026
regulation of cell sizeGO:0008361290.026
regulation of stem cell proliferationGO:007209120.026
skeletal muscle organ developmentGO:0060538780.026
inner ear morphogenesisGO:0042472630.026
cellular amide metabolic processGO:004360340.026
determination of left right symmetryGO:00073681790.026
regulation of localizationGO:00328791040.026
camera type eye morphogenesisGO:00485931080.025
regulation of anatomical structure morphogenesisGO:00226031300.025
protein acylationGO:004354330.025
cell morphogenesis involved in neuron differentiationGO:00486671630.025
cellular component assembly involved in morphogenesisGO:00109271070.025
myeloid cell homeostasisGO:0002262560.024
tissue remodelingGO:004877140.024
cellular response to endogenous stimulusGO:0071495680.024
transportGO:00068102200.024
proteolysis involved in cellular protein catabolic processGO:005160330.024
female sex differentiationGO:004666040.024
determination of dorsal identityGO:0048263130.024
response to organic substanceGO:00100331530.024
regulation of cell communicationGO:00106462320.024
cell motilityGO:00488702440.024
pharyngeal system developmentGO:0060037180.024
regulation of rna biosynthetic processGO:20011412130.024
homeostatic processGO:00425921420.023
golgi vesicle transportGO:004819330.023
cation transportGO:0006812810.023
nephron epithelium morphogenesisGO:007208810.023
regulation of production of molecular mediator of immune responseGO:000270010.023
renal tubule morphogenesisGO:006133310.023
circulatory system processGO:0003013870.023
phagocytosisGO:000690930.023
ion transmembrane transportGO:0034220910.023
sensory perception of painGO:001923310.023
ubiquitin dependent protein catabolic processGO:000651130.023
regulation of multicellular organism growthGO:004001440.022
myotube differentiationGO:0014902450.022
morphogenesis of an epithelial foldGO:006057110.022
mesenchymal cell developmentGO:0014031780.022
proepicardium developmentGO:000334240.022
positive regulation of cellular processGO:00485222010.022
cytosolic calcium ion transportGO:006040130.022
localization of cellGO:00516742440.022
internal peptidyl lysine acetylationGO:001839320.021
membrane fusionGO:006102520.021
specification of organ identityGO:001009220.021
behaviorGO:0007610740.021
embryonic skeletal joint developmentGO:007249830.021
cellular response to organic substanceGO:00713101050.021
response to nicotineGO:003509420.021
muscle fiber developmentGO:0048747520.021
regulation of cell differentiationGO:00455951420.021
neural retina developmentGO:0003407490.021
hemopoiesisGO:00300971830.021
neuron projection extensionGO:1990138450.021
somite developmentGO:0061053960.021
eye photoreceptor cell developmentGO:0042462300.021
carbohydrate biosynthetic processGO:001605110.020
protein localization to plasma membraneGO:007265910.020
regulation of synaptic plasticityGO:004816710.020
axonogenesisGO:00074091520.020
er to golgi vesicle mediated transportGO:000688810.020
skeletal muscle tissue developmentGO:0007519670.020
positive regulation of gene expressionGO:0010628710.020
wnt signaling pathway planar cell polarity pathwayGO:006007140.020
rna modificationGO:000945120.020
hatchingGO:003518840.020
action potentialGO:0001508190.020
organelle localizationGO:0051640490.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
apoptotic processGO:00069151160.020
nephron tubule morphogenesisGO:007207810.020
positive regulation of transportGO:005105020.020
regulation of locomotionGO:0040012550.020
erythrocyte homeostasisGO:0034101550.020
positive regulation of stress activated mapk cascadeGO:003287430.020
head developmentGO:00603223030.019
secondary metabolic processGO:001974830.019
protein localization to nucleusGO:003450430.019
cell migrationGO:00164772370.019
cellular protein metabolic processGO:00442671290.019
cell aggregationGO:009874330.019
ear developmentGO:00435831270.019
response to external stimulusGO:00096052640.019
regulation of mrna processingGO:005068430.019
positive regulation of biosynthetic processGO:0009891680.019
cell agingGO:000756920.019
fibroblast growth factor receptor signaling pathwayGO:0008543220.019
cell part morphogenesisGO:00329902460.019
dorsal ventral pattern formationGO:00099531250.019
heart loopingGO:0001947940.018
pericardium developmentGO:006003910.018
single organism localizationGO:19025782250.018
embryonic heart tube morphogenesisGO:00031431080.018
organism emergence from protective structureGO:007168440.018
mucopolysaccharide metabolic processGO:190351020.018
regulation of establishment of planar polarityGO:009017540.018
embryonic skeletal joint morphogenesisGO:006027230.018
post embryonic organ developmentGO:004856940.018
embryonic hemopoiesisGO:0035162530.018
myofibril assemblyGO:0030239480.018
peptidyl lysine acetylationGO:001839420.018
transcription from rna polymerase ii promoterGO:0006366800.018
positive regulation of canonical wnt signaling pathwayGO:009026340.018
sequestering of calcium ionGO:005120830.017
endochondral bone growthGO:000341620.017
protein acetylationGO:000647320.017
response to growth factorGO:0070848390.017
synaptic growth at neuromuscular junctionGO:005112420.017
single organism metabolic processGO:00447102170.017
growth plate cartilage developmentGO:000341720.017
endosomal transportGO:001619720.017
peptide metabolic processGO:000651810.017
monoamine transportGO:001584410.017
metal ion homeostasisGO:0055065260.017
hematopoietic stem cell differentiationGO:0060218200.017
programmed cell deathGO:00125011190.017
meiotic cell cycle processGO:190304630.017
zymogen activationGO:003163830.016
segmentationGO:0035282970.016
positive regulation of response to stimulusGO:0048584800.016
cellular response to reactive oxygen speciesGO:003461420.016
cell cycle processGO:0022402530.016
positive regulation of erk1 and erk2 cascadeGO:007037420.016
striated muscle cell developmentGO:00550021080.016
regulation of mesenchymal cell proliferationGO:001046410.016
fin regenerationGO:0031101510.016
digestive system developmentGO:00551232890.016
response to bacteriumGO:0009617580.016
regulation of reactive oxygen species metabolic processGO:200037720.016
regulation of cytokine productionGO:000181730.016
negative regulation of defense responseGO:003134820.016
single organism membrane fusionGO:004480120.016
larval developmentGO:000216420.016
regulation of skeletal muscle cell differentiationGO:200101410.016
regulation of cellular amine metabolic processGO:003323800.016
mitochondrion organizationGO:000700540.016
gastrulation with mouth forming secondGO:0001702440.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
positive regulation of stem cell proliferationGO:200064810.016
stem cell differentiationGO:00488631170.016
protein metabolic processGO:00195381830.016
response to hexoseGO:000974630.016
outflow tract morphogenesisGO:000315110.016
anterior posterior pattern specificationGO:00099521520.016
positive regulation of cell activationGO:005086710.016
cranial nerve developmentGO:0021545420.016
multicellular organism growthGO:003526440.015
epithelial tube morphogenesisGO:00605621480.015
regulation of chondrocyte differentiationGO:003233010.015
response to endogenous stimulusGO:0009719830.015
appendage developmentGO:0048736800.015
deathGO:00162651210.015
negative regulation of developmental processGO:0051093650.015
response to other organismGO:0051707970.015
sex determinationGO:000753010.015
internal protein amino acid acetylationGO:000647520.015
calcium ion transport into cytosolGO:006040230.015
regulation of cellular component organizationGO:0051128860.015
invagination involved in gastrulation with mouth forming secondGO:005510910.015
developmental growth involved in morphogenesisGO:0060560860.015
organelle fusionGO:004828430.015
development of primary female sexual characteristicsGO:004654540.015
negative regulation of protein serine threonine kinase activityGO:007190120.015
positive regulation of cytoskeleton organizationGO:005149530.015
embryonic viscerocranium morphogenesisGO:0048703520.015
response to external biotic stimulusGO:0043207970.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
response to monosaccharideGO:003428430.014
positive regulation of nucleic acid templated transcriptionGO:1903508570.014
release of sequestered calcium ion into cytosolGO:005120930.014
cellular response to growth factor stimulusGO:0071363390.014
regulation of response to external stimulusGO:0032101310.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
ameboidal type cell migrationGO:00016671430.014
meiotic chromosome segregationGO:004513230.014
response to biotic stimulusGO:0009607970.014
negative regulation of wnt signaling pathwayGO:0030178300.014
regulation of alternative mrna splicing via spliceosomeGO:000038110.014
transmembrane transportGO:00550851200.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.014
amine metabolic processGO:000930820.014
negative regulation of epithelial cell proliferationGO:005068010.014
axon developmentGO:00615641660.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
positive regulation of cytokine productionGO:000181920.014
regulation of cell deathGO:00109411030.014
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.014
regulation of nucleoside metabolic processGO:000911820.014
positive regulation of mesenchymal cell proliferationGO:000205310.014
wnt signaling pathwayGO:0016055800.014
regulation of sequestering of calcium ionGO:005128240.014
cytoskeleton organizationGO:0007010960.014
cellular response to fibroblast growth factor stimulusGO:0044344220.014
regulation of wnt signaling pathwayGO:0030111530.014
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.014
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.014
chemotaxisGO:00069351040.014
establishment of localization in cellGO:0051649770.014
negative regulation of signalingGO:0023057960.014
cell projection organizationGO:00300302840.014
lateral line system developmentGO:0048925760.014
convergent extensionGO:00600261180.014
regulation of extent of cell growthGO:0061387290.014
response to carbohydrateGO:000974330.014
positive regulation of cellular biosynthetic processGO:0031328680.014
positive regulation of blood circulationGO:190352420.014
regulation of syncytium formation by plasma membrane fusionGO:006014220.014
positive regulation of reproductive processGO:200024320.014
negative regulation of protein phosphorylationGO:000193340.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.014
defense response to other organismGO:0098542330.013
fin morphogenesisGO:0033334530.013
rna localizationGO:000640340.013
protein modification processGO:00362111000.013
axon extensionGO:0048675450.013
cellular response to retinoic acidGO:007130010.013
olfactory bulb developmentGO:002177240.013
signal transduction in absence of ligandGO:003803410.013
neuromast developmentGO:0048884460.013
spermatid developmentGO:000728620.013
positive regulation of secretionGO:005104710.013
intracellular signal transductionGO:0035556850.013
histone h3 k4 methylationGO:005156820.013
heterocycle biosynthetic processGO:00181302150.013
response to axon injuryGO:0048678140.013
regulation of system processGO:0044057400.013
regulation of cellular component movementGO:0051270550.013
protein import into nucleusGO:000660630.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
positive regulation of rna biosynthetic processGO:1902680570.013
ribonucleoside monophosphate catabolic processGO:000915840.013
erk1 and erk2 cascadeGO:007037140.013
negative regulation of cellular metabolic processGO:0031324770.013
positive regulation of signal transductionGO:0009967560.013
neuron projection guidanceGO:0097485860.013
negative regulation of cell communicationGO:0010648960.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
organic acid metabolic processGO:0006082310.013
muscle cell developmentGO:00550011150.013
sensory system developmentGO:0048880760.013
retina morphogenesis in camera type eyeGO:0060042790.012
regulation of bindingGO:005109830.012
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
nephron morphogenesisGO:007202820.012
regulation of cell cycleGO:0051726520.012
regulation of endothelial cell proliferationGO:000193610.012
cognitionGO:005089010.012
positive regulation of myeloid cell differentiationGO:004563920.012
regulation of transporter activityGO:003240920.012
limb bud formationGO:006017420.012
appendage morphogenesisGO:0035107560.012
sympathetic ganglion developmentGO:006154920.012
single organism transportGO:00447652060.012
branchiomotor neuron axon guidanceGO:002178510.012
blood circulationGO:0008015870.012
regulation of cytoplasmic transportGO:190364940.012
protein complex disassemblyGO:004324110.012
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.012
antimicrobial humoral responseGO:001973020.012
nucleic acid transportGO:005065720.012
response to uvGO:000941130.012
regulation of blood vessel sizeGO:005088020.012
cilium morphogenesisGO:0060271850.012
establishment of organelle localizationGO:0051656450.012
production of molecular mediator of immune responseGO:000244020.012
catechol containing compound metabolic processGO:000971220.012
epithelial to mesenchymal transitionGO:0001837210.012
positive regulation of cellular metabolic processGO:0031325940.012
multicellular organismal response to stressGO:003355520.012
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.012
response to glucoseGO:000974930.012
heart developmentGO:00075073130.012
actomyosin structure organizationGO:0031032530.012
regulation of neurogenesisGO:0050767870.012
convergent extension involved in gastrulationGO:0060027710.012
membrane repolarizationGO:008600920.012
kidney epithelium developmentGO:0072073230.012
amide biosynthetic processGO:004360410.012
cellular protein modification processGO:00064641000.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.012
regulation of cell growthGO:0001558290.012
positive regulation of cellular catabolic processGO:003133130.012
multicellular organismal signalingGO:0035637220.012
kidney developmentGO:0001822920.012
cellular transition metal ion homeostasisGO:004691630.012
regulation of meiotic cell cycleGO:005144510.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
protein depolymerizationGO:005126110.012
regulation of cellular component sizeGO:0032535300.011
positive regulation of epithelial cell proliferationGO:005067910.011
apoptotic signaling pathwayGO:0097190230.011
neuron neuron synaptic transmissionGO:000727010.011
atp catabolic processGO:000620040.011
retinal cone cell developmentGO:004654980.011
cellular response to radiationGO:007147840.011
ear morphogenesisGO:0042471640.011
synaptic vesicle transportGO:004848910.011
negative regulation of response to stimulusGO:00485851040.011
positive regulation of endothelial cell proliferationGO:000193810.011
eye field cell fate commitment involved in camera type eye formationGO:006089830.011
establishment of protein localization to organelleGO:007259440.011
organonitrogen compound metabolic processGO:1901564740.011
smooth muscle contractionGO:000693920.011
positive regulation of striated muscle tissue developmentGO:004584410.011
photoreceptor cell fate commitmentGO:004655210.011
negative regulation of gene expressionGO:0010629650.011
growthGO:00400071740.011
developmental cell growthGO:0048588520.011
lipid catabolic processGO:001604240.011
neurotransmitter transportGO:000683620.011
myosin filament organizationGO:003103360.011
cellular carbohydrate metabolic processGO:004426240.011
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.011
regulation of membrane potentialGO:0042391230.011
mesoderm developmentGO:0007498880.011
pigment granule localizationGO:0051875250.011
neuron projection morphogenesisGO:00488121610.011
regulation of cellular protein catabolic processGO:190336210.011
positive regulation of dna templated transcription elongationGO:003278610.011

LOC556647 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
urinary system diseaseDOID:1800.019
organ system cancerDOID:005068600.017
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
nervous system diseaseDOID:86300.015