Danio rerio

0 known processes

bfb

complement component bfb

(Aliases: Bf-2)

bfb biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.136
regulation of circadian rhythmGO:004275240.116
central nervous system developmentGO:00074173870.116
regulation of wound healingGO:006104120.114
small molecule metabolic processGO:0044281770.096
maintenance of locationGO:005123540.092
agingGO:000756820.087
circadian sleep wake cycleGO:004274520.084
brain developmentGO:00074202930.081
multicellular organism growthGO:003526440.068
cellular macromolecule biosynthetic processGO:00346452240.068
response to ketoneGO:190165410.066
neuron differentiationGO:00301823530.064
organic acid metabolic processGO:0006082310.062
cellular response to chemical stimulusGO:00708871570.060
generation of neuronsGO:00486993850.059
response to organic substanceGO:00100331530.056
cognitionGO:005089010.055
cellular nitrogen compound biosynthetic processGO:00442712180.054
regulation of circadian sleep wake cycleGO:004274910.053
oxoacid metabolic processGO:0043436310.053
heterocycle metabolic processGO:00464832900.051
regulation of cellular biosynthetic processGO:00313262450.049
cellular component morphogenesisGO:00329893360.049
cellular biosynthetic processGO:00442492860.049
circadian sleep wake cycle processGO:002241020.048
positive regulation of protein kinase b signalingGO:005189710.048
response to endogenous stimulusGO:0009719830.048
cell motilityGO:00488702440.047
spermatid developmentGO:000728620.047
sleepGO:003043110.046
nucleic acid templated transcriptionGO:00976591810.045
cellular macromolecule metabolic processGO:00442603910.044
phagocytosisGO:000690930.044
circadian sleep wake cycle sleepGO:005080210.044
regulation of circadian sleep wake cycle sleepGO:004518710.043
amine metabolic processGO:000930820.043
positive regulation of transportGO:005105020.043
macromolecule biosynthetic processGO:00090592270.041
angiogenesisGO:00015251580.041
cellular response to organic cyclic compoundGO:0071407380.041
dicarboxylic acid transportGO:000683510.041
cell morphogenesisGO:00009022890.040
growthGO:00400071740.040
response to lipidGO:0033993600.040
nucleic acid metabolic processGO:00903042440.040
cellular respirationGO:004533330.040
synaptic growth at neuromuscular junctionGO:005112420.040
immune system processGO:00023762410.039
locomotionGO:00400113130.038
neuroblast proliferationGO:000740520.038
regulation of multicellular organism growthGO:004001440.038
regionalizationGO:00030022740.038
regulation of cytokine productionGO:000181730.037
negative regulation of multicellular organismal processGO:0051241690.036
heart morphogenesisGO:00030071560.035
autophagyGO:000691440.035
cell part morphogenesisGO:00329902460.035
response to steroid hormoneGO:0048545350.034
cellular component disassemblyGO:002241110.034
heart developmentGO:00075073130.034
response to alkaloidGO:004327920.034
muscle cell developmentGO:00550011150.034
cellular component movementGO:00069283350.034
heterocycle biosynthetic processGO:00181302150.034
small molecule catabolic processGO:004428230.033
carboxylic acid metabolic processGO:0019752220.033
response to woundingGO:00096111160.033
organism emergence from protective structureGO:007168440.033
stem cell proliferationGO:007208940.033
biosynthetic processGO:00090582940.032
wound healingGO:0042060900.032
cellular response to organic substanceGO:00713101050.032
regulation of cellular amine metabolic processGO:003323800.032
single organism metabolic processGO:00447102170.032
regulation of peptidyl tyrosine phosphorylationGO:005073010.031
spermatid differentiationGO:004851520.031
nitrogen compound metabolic processGO:00068073190.031
circulatory system processGO:0003013870.030
blood vessel morphogenesisGO:00485142160.030
cellular aromatic compound metabolic processGO:00067252950.030
rna metabolic processGO:00160702190.030
head developmentGO:00603223030.030
positive regulation of wound healingGO:009030310.029
oxidation reduction processGO:0055114410.029
response to hormoneGO:0009725480.029
stem cell differentiationGO:00488631170.029
signal transductionGO:00071654550.029
regulation of organ growthGO:004662030.029
regulation of metabolic processGO:00192223590.029
blood coagulationGO:0007596120.029
synaptic target recognitionGO:000803910.029
regulation of synapse organizationGO:005080730.028
developmental growthGO:00485891660.028
regenerationGO:0031099910.028
regulation of synapse assemblyGO:005196330.028
regulation of neural precursor cell proliferationGO:200017730.028
monoamine transportGO:001584410.028
meiotic nuclear divisionGO:000712640.028
cellular response to steroid hormone stimulusGO:0071383310.028
lipid storageGO:001991510.028
cell morphogenesis involved in differentiationGO:00009041950.028
nucleobase containing compound biosynthetic processGO:00346542050.028
hemostasisGO:0007599130.028
regulation of biosynthetic processGO:00098892500.028
system processGO:00030081850.027
transcription dna templatedGO:00063511810.027
symbiosis encompassing mutualism through parasitismGO:004440340.027
regulation of biological qualityGO:00650082630.026
cellular amine metabolic processGO:004410620.026
long chain fatty acid metabolic processGO:000167610.026
response to chemicalGO:00422213200.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
multi organism processGO:00517041340.026
Zebrafish
regulation of blood vessel sizeGO:005088020.026
hormone transportGO:000991420.026
negative regulation of biological processGO:00485193040.026
muscle structure developmentGO:00610611960.026
regulation of transcription dna templatedGO:00063552130.026
regulation of response to stimulusGO:00485832690.025
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.025
cellular amino acid metabolic processGO:000652070.025
response to vitaminGO:003327330.025
oxalate transportGO:001953210.025
cell projection organizationGO:00300302840.025
cellular response to estrogen stimulusGO:0071391240.025
positive regulation of secretion by cellGO:190353210.025
positive regulation of cellular amine metabolic processGO:003324000.025
deathGO:00162651210.025
regulation of cellular amino acid metabolic processGO:000652100.024
regulation of blood coagulationGO:003019310.024
interspecies interaction between organismsGO:004441940.024
cellular ketone metabolic processGO:0042180110.024
regulation of developmental processGO:00507932470.024
regulation of macromolecule biosynthetic processGO:00105562250.024
neuron remodelingGO:001632210.024
regulation of cellular macromolecule biosynthetic processGO:20001122220.023
nucleobase containing compound metabolic processGO:00061392740.023
response to glucoseGO:000974930.023
response to estrogenGO:0043627270.023
embryo development ending in birth or egg hatchingGO:00097922710.023
mitochondrion organizationGO:000700540.023
phagocytosis engulfmentGO:000691110.023
response to nutrientGO:000758430.023
organic acid catabolic processGO:001605430.023
membrane invaginationGO:001032410.023
aromatic compound biosynthetic processGO:00194382170.022
negative regulation of cellular processGO:00485232830.022
germ line stem cell maintenanceGO:003071820.022
cellular nitrogen compound metabolic processGO:00346412900.022
rna biosynthetic processGO:00327741810.022
cellular response to lipidGO:0071396390.022
regulation of response to stressGO:0080134360.022
lipid homeostasisGO:005508830.022
response to drugGO:004249330.022
regulation of erk1 and erk2 cascadeGO:007037240.022
protein import into nucleusGO:000660630.022
response to other organismGO:0051707970.022
Zebrafish
regulation of multicellular organismal processGO:00512392770.022
digestive tract developmentGO:00485652650.022
regulation of protein transportGO:005122330.021
regulation of cellular ketone metabolic processGO:001056570.021
response to carbohydrateGO:000974330.021
cellular component biogenesisGO:00440851780.021
coagulationGO:0050817130.021
meiotic cell cycle processGO:190304630.021
embryonic organ developmentGO:00485683810.021
regulation of multicellular organismal developmentGO:20000262230.021
hormone secretionGO:004687920.021
organic cyclic compound biosynthetic processGO:19013622230.021
regulation of autophagyGO:001050630.021
regulation of nitrogen compound metabolic processGO:00511712510.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
cellular protein catabolic processGO:004425740.020
regulation of tube sizeGO:003515020.020
carboxylic acid catabolic processGO:004639530.020
positive regulation of secretionGO:005104710.020
cellular response to hormone stimulusGO:0032870390.020
peripheral nervous system developmentGO:0007422550.020
cell migrationGO:00164772370.020
regulation of blood pressureGO:000821710.020
positive regulation of muscle organ developmentGO:004863610.020
positive regulation of blood circulationGO:190352420.020
regulation of cell activationGO:005086510.020
circadian rhythmGO:0007623190.020
stem cell maintenanceGO:001982740.019
regulation of dendrite developmentGO:005077330.019
protein localization to nucleusGO:003450430.019
regulation of rna metabolic processGO:00512522240.019
response to organic cyclic compoundGO:0014070510.019
epithelial cell differentiationGO:00308551160.019
neuron projection morphogenesisGO:00488121610.019
striated muscle tissue developmentGO:00147061100.019
rhythmic processGO:0048511210.019
mesenchyme developmentGO:00604851270.019
complement activationGO:000695630.019
organic substance biosynthetic processGO:19015762890.019
cellular response to endogenous stimulusGO:0071495680.019
neurological system processGO:0050877620.018
cellular response to methanolGO:007140540.018
peptidyl serine phosphorylationGO:001810510.018
cell substrate adhesionGO:003158940.018
embryonic cranial skeleton morphogenesisGO:0048701900.018
response to monosaccharideGO:003428430.018
positive regulation of cellular processGO:00485222010.018
sensory organ morphogenesisGO:00905962000.018
regulation of protein complex assemblyGO:004325430.018
positive regulation of cell adhesionGO:004578510.018
stem cell divisionGO:001714510.018
response to external biotic stimulusGO:0043207970.018
Zebrafish
chemosensory behaviorGO:000763510.018
axon developmentGO:00615641660.018
positive regulation of cytokine productionGO:000181920.018
female sex differentiationGO:004666040.018
regulation of cellular carbohydrate metabolic processGO:001067540.018
regulation of rna biosynthetic processGO:20011412130.018
hatchingGO:003518840.018
nuclear transportGO:005116940.018
digestive system developmentGO:00551232890.018
positive regulation of cellular component biogenesisGO:004408930.018
cellular component assemblyGO:00226071700.018
regulation of reproductive processGO:200024140.018
behaviorGO:0007610740.018
blood coagulation fibrin clot formationGO:007237830.017
negative regulation of developmental processGO:0051093650.017
establishment of protein localization to organelleGO:007259440.017
regulation of cell substrate adhesionGO:001081010.017
peptide metabolic processGO:000651810.017
embryonic organ morphogenesisGO:00485622740.017
intracellular signal transductionGO:0035556850.017
protein targeting to nucleusGO:004474430.017
organic cyclic compound metabolic processGO:19013603010.017
lipid oxidationGO:003444010.017
somatic muscle developmentGO:000752540.017
photoreceptor cell differentiationGO:0046530550.017
neurotransmitter transportGO:000683620.017
gene expressionGO:00104672520.017
negative regulation of response to stimulusGO:00485851040.017
secondary metabolic processGO:001974830.016
single organism localizationGO:19025782250.016
response to hexoseGO:000974630.016
organonitrogen compound metabolic processGO:1901564740.016
response to external stimulusGO:00096052640.016
Zebrafish
regulation of apoptotic processGO:0042981980.016
regulation of hormone secretionGO:004688320.016
reactive oxygen species biosynthetic processGO:190340910.016
regulation of systemic arterial blood pressureGO:000307310.016
glial cell migrationGO:000834730.016
regulation of carbohydrate metabolic processGO:000610940.016
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.016
single organism nuclear importGO:190259330.016
response to glucocorticoidGO:005138410.016
periodic partitioningGO:000736510.016
protein importGO:001703830.016
erk1 and erk2 cascadeGO:007037140.016
transportGO:00068102200.016
localization of cellGO:00516742440.016
eye developmentGO:00016542770.016
carbohydrate biosynthetic processGO:001605110.015
regulation of cell shapeGO:000836010.015
positive regulation of cellular catabolic processGO:003133130.015
immune system developmentGO:00025201910.015
b cell activationGO:004211320.015
protein localization to plasma membraneGO:007265910.015
response to hydrogen peroxideGO:004254230.015
extracellular structure organizationGO:0043062270.015
internal peptidyl lysine acetylationGO:001839320.015
muscle cell differentiationGO:00426921390.015
leukocyte proliferationGO:007066110.015
blood circulationGO:0008015870.015
glucose importGO:004632320.015
lipid catabolic processGO:001604240.015
nuclear importGO:005117030.015
single organism transportGO:00447652060.015
morphogenesis of an epitheliumGO:00020093330.015
regulation of coagulationGO:005081820.015
hindbrain developmentGO:0030902910.015
fat soluble vitamin metabolic processGO:000677540.015
epidermis developmentGO:0008544480.015
negative regulation of signalingGO:0023057960.015
hemopoiesisGO:00300971830.015
positive regulation of cell cycleGO:004578730.015
fatty acid catabolic processGO:000906210.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
establishment of localizationGO:00512342440.015
regulation of cell communicationGO:00106462320.015
regulation of cytoplasmic transportGO:190364940.015
post embryonic organ developmentGO:004856940.015
negative regulation of neural precursor cell proliferationGO:200017810.015
protein secretionGO:000930610.015
response to stressGO:00069502630.014
cellular carbohydrate metabolic processGO:004426240.014
regulation of programmed cell deathGO:00430671010.014
positive regulation of cell activationGO:005086710.014
regulation of inflammatory responseGO:005072720.014
negative regulation of defense responseGO:003134820.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
neuron projection developmentGO:00311751800.014
regulation of cell projection assemblyGO:006049140.014
regulation of hemostasisGO:190004610.014
peptidyl serine modificationGO:001820920.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
production of molecular mediator of immune responseGO:000244020.014
response to corticosteroidGO:003196010.014
positive regulation of immune effector processGO:000269930.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
positive regulation of leukocyte migrationGO:000268720.014
female meiotic divisionGO:000714320.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
positive regulation of catabolic processGO:000989640.014
regulation of gene expressionGO:00104682650.014
response to amphetamineGO:000197510.014
regulation of response to external stimulusGO:0032101310.014
regulation of dna replicationGO:000627530.013
renal tubule morphogenesisGO:006133310.013
ether metabolic processGO:001890410.013
regulation of cellular metabolic processGO:00313233200.013
cellular response to external stimulusGO:007149620.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
cell matrix adhesionGO:000716040.013
determination of bilateral symmetryGO:00098552040.013
monocarboxylic acid catabolic processGO:007232930.013
regulation of signal transductionGO:00099662250.013
response to biotic stimulusGO:0009607970.013
Zebrafish
sensory perception of chemical stimulusGO:000760630.013
cellular aldehyde metabolic processGO:000608140.013
mononuclear cell proliferationGO:003294310.013
gtp catabolic processGO:000618420.013
mitotic dna damage checkpointGO:004477340.013
regulation of dendrite morphogenesisGO:004881430.013
protein acetylationGO:000647320.013
protein acylationGO:004354330.013
tissue remodelingGO:004877140.013
regulation of establishment of protein localizationGO:007020140.013
negative regulation of synapse assemblyGO:005196420.013
reactive nitrogen species metabolic processGO:200105700.013
regulation of cell developmentGO:00602841000.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
protein homooligomerizationGO:005126030.012
protein polymerizationGO:005125840.012
apical junction assemblyGO:004329710.012
adult behaviorGO:003053420.012
regulation of glucose transportGO:001082710.012
extrinsic apoptotic signaling pathwayGO:009719130.012
single organism organelle organizationGO:19025891990.012
b cell differentiationGO:003018310.012
lymphocyte proliferationGO:004665110.012
regulation of intracellular protein transportGO:003315730.012
regulation of growth rateGO:004000910.012
locomotor rhythmGO:004547530.012
response to bacteriumGO:0009617580.012
Zebrafish
regulation of protein localization to nucleusGO:190018020.012
cell deathGO:00082191210.012
regulation of neurotransmitter secretionGO:004692810.012
sensory organ developmentGO:00074233930.012
positive regulation of leukocyte chemotaxisGO:000269010.012
appendage developmentGO:0048736800.012
glucose homeostasisGO:004259310.012
chordate embryonic developmentGO:00430092710.012
nitric oxide biosynthetic processGO:000680920.012
mycotoxin metabolic processGO:004338510.012
regulation of reactive oxygen species metabolic processGO:200037720.012
positive regulation of leukocyte differentiationGO:190210710.012
regulation of production of molecular mediator of immune responseGO:000270010.012
multicellular organismal response to stressGO:003355520.012
regulation of protein import into nucleusGO:004230620.012
dopamine metabolic processGO:004241720.012
positive regulation of biological processGO:00485182530.012
cell cycle g1 s phase transitionGO:004484310.012
positive regulation of map kinase activityGO:004340630.012
organelle organizationGO:00069962270.012
regulation of synaptic plasticityGO:004816710.012
guanosine containing compound metabolic processGO:190106840.012
positive regulation of cellular carbohydrate metabolic processGO:001067610.012
carbohydrate homeostasisGO:003350010.012
regulation of cellular protein catabolic processGO:190336210.012
golgi vesicle transportGO:004819330.012
eye morphogenesisGO:00485921440.011
regulation of nucleocytoplasmic transportGO:004682220.011
striated muscle cell developmentGO:00550021080.011
protein metabolic processGO:00195381830.011
negative regulation of cell differentiationGO:0045596460.011
cellular protein metabolic processGO:00442671290.011
nucleocytoplasmic transportGO:000691340.011
pancreas developmentGO:0031016840.011
programmed cell deathGO:00125011190.011
muscle organ developmentGO:00075171010.011
chemical homeostasisGO:0048878490.011
response to amineGO:001407510.011
type b pancreatic cell developmentGO:000332340.011
peptidyl lysine acetylationGO:001839420.011
regulation of cellular component movementGO:0051270550.011
negative regulation of multi organism processGO:004390130.011
neural crest cell differentiationGO:0014033720.011
organelle assemblyGO:00709251100.011
cellular response to extracellular stimulusGO:003166820.011
positive regulation of dna metabolic processGO:005105410.011
gtp metabolic processGO:004603940.011
cellular lipid catabolic processGO:004424230.011
cell projection morphogenesisGO:00488582440.011
pronuclear migrationGO:003504610.011
regulation of protein catabolic processGO:004217610.011
hepaticobiliary system developmentGO:0061008980.011
peptide transportGO:001583310.011
phosphatidylinositol mediated signalingGO:004801520.011
embryonic heart tube morphogenesisGO:00031431080.011
regulation of protein kinase b signalingGO:005189680.011
positive regulation of jnk cascadeGO:004633030.011
antimicrobial humoral responseGO:001973020.011
regulation of neurogenesisGO:0050767870.011
cellular response to nutrient levelsGO:003166920.011
regulation of protein targetingGO:190353320.011
fatty acid biosynthetic processGO:000663340.011
vasculature developmentGO:00019442780.011
regulation of stem cell differentiationGO:200073640.011
taxisGO:00423301090.011
guanosine containing compound catabolic processGO:190106920.011
neurotransmitter secretionGO:000726920.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
compound eye developmentGO:004874920.011
regulation of cell deathGO:00109411030.011
macromolecular complex disassemblyGO:003298410.011
regulation of macromolecule metabolic processGO:00602553170.011
positive regulation of myeloid cell differentiationGO:004563920.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
positive regulation of carbohydrate metabolic processGO:004591310.011
meiotic chromosome segregationGO:004513230.011
regulation of signalingGO:00230512350.011
regulation of mesenchymal cell proliferationGO:001046410.011
endocrine system developmentGO:0035270650.011
apoptotic process involved in developmentGO:190274220.011
negative regulation of nucleocytoplasmic transportGO:004682320.010
regulation of epithelial cell proliferationGO:005067830.010
positive regulation of epithelial cell migrationGO:001063420.010
nuclear migrationGO:000709730.010
mesenchymal cell developmentGO:0014031780.010
negative regulation of dna metabolic processGO:005105340.010
specification of symmetryGO:00097992040.010
g1 s transition of mitotic cell cycleGO:000008210.010
nephron tubule morphogenesisGO:007207810.010
camera type eye developmentGO:00430102220.010
negative regulation of signal transductionGO:0009968940.010
nitric oxide metabolic processGO:004620920.010
adherens junction organizationGO:003433240.010
cellular response to growth factor stimulusGO:0071363390.010
catecholamine metabolic processGO:000658420.010
exocrine pancreas developmentGO:0031017280.010
neuromuscular synaptic transmissionGO:000727420.010
positive regulation of response to stimulusGO:0048584800.010
rna localizationGO:000640340.010
renal system developmentGO:0072001940.010
regulation of gtpase activityGO:004308720.010
cellular response to starvationGO:000926710.010
cell surface receptor signaling pathwayGO:00071663250.010
regulation of mrna splicing via spliceosomeGO:004802430.010
hematopoietic or lymphoid organ developmentGO:00485341910.010
regulation of stem cell proliferationGO:007209120.010
protein complex disassemblyGO:004324110.010
homeostatic processGO:00425921420.010

bfb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
disease of metabolismDOID:001466700.021
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.014
cancerDOID:16200.014
sensory system diseaseDOID:005015500.014
eye diseaseDOID:561400.014
eye and adnexa diseaseDOID:149200.014
retinal diseaseDOID:567900.012
immune system diseaseDOID:291400.010
hematopoietic system diseaseDOID:7400.010