Danio rerio

43 known processes

pls3

plastin 3 (T isoform)

(Aliases: wu:fc04g03,zgc:91903)

pls3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular component biogenesisGO:004408930.148
larval developmentGO:000216420.131
response to chemicalGO:00422213200.112
agingGO:000756820.098
response to external stimulusGO:00096052640.096
generation of neuronsGO:00486993850.080
neuron projection morphogenesisGO:00488121610.078
cellular nitrogen compound metabolic processGO:00346412900.077
response to stressGO:00069502630.061
cell projection morphogenesisGO:00488582440.060
neuron developmentGO:00486662620.060
morphogenesis of an epitheliumGO:00020093330.058
cell morphogenesis involved in differentiationGO:00009041950.057
cellular component morphogenesisGO:00329893360.056
eye developmentGO:00016542770.055
positive regulation of transportGO:005105020.054
cellular response to external stimulusGO:007149620.049
regulation of cell projection assemblyGO:006049140.049
heterocycle metabolic processGO:00464832900.048
phagocytosisGO:000690930.048
gene expressionGO:00104672520.047
axonogenesisGO:00074091520.045
cell substrate adhesionGO:003158940.045
response to transition metal nanoparticleGO:1990267280.045
single organism metabolic processGO:00447102170.044
multicellular organism growthGO:003526440.044
response to woundingGO:00096111160.043
sensory organ developmentGO:00074233930.042
regulation of multicellular organism growthGO:004001440.042
regulation of establishment of protein localizationGO:007020140.042
response to inorganic substanceGO:0010035380.041
cell morphogenesis involved in neuron differentiationGO:00486671630.041
nucleobase containing compound metabolic processGO:00061392740.040
nuclear transportGO:005116940.040
embryonic organ morphogenesisGO:00485622740.040
regulation of synapse organizationGO:005080730.039
single organism organelle organizationGO:19025891990.039
regulation of metabolic processGO:00192223590.039
cellular macromolecule metabolic processGO:00442603910.039
regulation of cellular metabolic processGO:00313233200.039
positive regulation of protein complex assemblyGO:003133420.038
maintenance of locationGO:005123540.038
protein localization to nucleusGO:003450430.038
blood vessel developmentGO:00015682460.037
cellular component movementGO:00069283350.037
neuron projection developmentGO:00311751800.037
sensory perception of chemical stimulusGO:000760630.036
adult behaviorGO:003053420.036
positive regulation of catabolic processGO:000989640.035
cellular response to starvationGO:000926710.035
developmental growth involved in morphogenesisGO:0060560860.035
autophagyGO:000691440.035
nitrogen compound metabolic processGO:00068073190.034
tube morphogenesisGO:00352393490.034
cognitionGO:005089010.034
signal transductionGO:00071654550.034
response to organic substanceGO:00100331530.034
cell projection organizationGO:00300302840.034
regulation of protein transportGO:005122330.034
cellular response to extracellular stimulusGO:003166820.034
embryonic organ developmentGO:00485683810.034
cell motilityGO:00488702440.034
developmental growthGO:00485891660.034
regulation of cellular amino acid metabolic processGO:000652100.033
axon developmentGO:00615641660.033
protein import into nucleusGO:000660630.033
response to drugGO:004249330.033
cell part morphogenesisGO:00329902460.033
guanosine containing compound metabolic processGO:190106840.033
response to monosaccharideGO:003428430.032
cellular response to chemical stimulusGO:00708871570.032
regulation of synapse assemblyGO:005196330.032
negative regulation of biological processGO:00485193040.032
regulation of primary metabolic processGO:00800903110.032
protein metabolic processGO:00195381830.032
nucleocytoplasmic transportGO:000691340.031
positive regulation of cell cycleGO:004578730.031
organelle fusionGO:004828430.031
protein polymerizationGO:005125840.031
regulation of nucleocytoplasmic transportGO:004682220.030
regulation of filopodium assemblyGO:005148920.030
regulation of protein complex assemblyGO:004325430.030
positive regulation of secretion by cellGO:190353210.030
stem cell proliferationGO:007208940.030
regulation of cytokine productionGO:000181730.030
chemotaxisGO:00069351040.030
regulation of macromolecule metabolic processGO:00602553170.030
establishment of localizationGO:00512342440.030
central nervous system developmentGO:00074173870.030
stem cell maintenanceGO:001982740.030
regulation of cell shapeGO:000836010.030
response to carbohydrateGO:000974330.029
actin polymerization or depolymerizationGO:000815420.029
synaptic growth at neuromuscular junctionGO:005112420.029
regulation of protein polymerizationGO:003227120.029
amine metabolic processGO:000930820.029
positive regulation of cellular catabolic processGO:003133130.029
regulation of cellular amine metabolic processGO:003323800.029
neuron neuron synaptic transmissionGO:000727010.029
gtp catabolic processGO:000618420.028
immune system processGO:00023762410.028
protein targeting to nucleusGO:004474430.028
regulation of extrinsic apoptotic signaling pathwayGO:200123630.028
vasculature developmentGO:00019442780.028
single organism nuclear importGO:190259330.028
nucleic acid metabolic processGO:00903042440.028
regulation of wound healingGO:006104120.028
establishment of protein localization to organelleGO:007259440.028
regulation of nucleoside metabolic processGO:000911820.028
growthGO:00400071740.028
membrane fusionGO:006102520.028
muscle structure developmentGO:00610611960.027
gtp metabolic processGO:004603940.027
regulation of i kappab kinase nf kappab signalingGO:004312240.027
peptidyl serine phosphorylationGO:001810510.027
biosynthetic processGO:00090582940.027
cell morphogenesisGO:00009022890.027
i kappab kinase nf kappab signalingGO:000724940.027
regulation of nitrogen compound metabolic processGO:00511712510.027
regulation of cell activationGO:005086510.027
positive regulation of protein polymerizationGO:003227320.027
determination of bilateral symmetryGO:00098552040.027
tissue remodelingGO:004877140.026
response to hydrogen peroxideGO:004254230.026
peptidyl serine modificationGO:001820920.026
cellular response to nutrient levelsGO:003166920.026
cellular amine metabolic processGO:004410620.026
single organism membrane fusionGO:004480120.026
blood vessel morphogenesisGO:00485142160.026
apoptotic processGO:00069151160.026
response to glucoseGO:000974930.026
protein secretionGO:000930610.026
single organism localizationGO:19025782250.026
response to hexoseGO:000974630.026
cellular macromolecule biosynthetic processGO:00346452240.026
mitochondrion organizationGO:000700540.026
response to abiotic stimulusGO:00096281220.026
system processGO:00030081850.026
organic substance biosynthetic processGO:19015762890.026
regulation of biological qualityGO:00650082630.026
localization of cellGO:00516742440.026
digestive system developmentGO:00551232890.025
heart developmentGO:00075073130.025
organic cyclic compound metabolic processGO:19013603010.025
guanosine containing compound catabolic processGO:190106920.025
sensory system developmentGO:0048880760.025
positive regulation of cellular processGO:00485222010.025
cortical actin cytoskeleton organizationGO:003086610.025
embryo development ending in birth or egg hatchingGO:00097922710.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.025
nuclear importGO:005117030.025
cellular component assemblyGO:00226071700.024
regulation of protein localization to nucleusGO:190018020.024
multi organism cellular processGO:004476420.024
epithelial tube morphogenesisGO:00605621480.024
regulation of bindingGO:005109830.024
negative regulation of protein phosphorylationGO:000193340.024
dicarboxylic acid transportGO:000683510.024
chordate embryonic developmentGO:00430092710.023
camera type eye developmentGO:00430102220.023
organic cyclic compound biosynthetic processGO:19013622230.023
cellular response to oxygen levelsGO:007145310.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.023
protein importGO:001703830.023
developmental cell growthGO:0048588520.023
gland developmentGO:00487321430.023
neuroblast proliferationGO:000740520.023
response to amino acidGO:004320020.023
regulation of nucleotide catabolic processGO:003081120.023
positive regulation of cell adhesionGO:004578510.022
cellular response to hypoxiaGO:007145610.022
cell migrationGO:00164772370.022
positive regulation of i kappab kinase nf kappab signalingGO:004312330.022
rna metabolic processGO:00160702190.022
neuron differentiationGO:00301823530.022
angiogenesisGO:00015251580.022
cellular response to organic substanceGO:00713101050.022
specification of symmetryGO:00097992040.022
cell matrix adhesionGO:000716040.021
cellular component biogenesisGO:00440851780.021
single organism transportGO:00447652060.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
leukocyte proliferationGO:007066110.021
cellular component disassemblyGO:002241110.021
digestive tract developmentGO:00485652650.021
response to glucocorticoidGO:005138410.021
protein heterooligomerizationGO:005129110.021
phosphate containing compound metabolic processGO:00067961080.021
peptide transportGO:001583310.021
organonitrogen compound metabolic processGO:1901564740.021
positive regulation of biological processGO:00485182530.021
regenerationGO:0031099910.021
production of molecular mediator of immune responseGO:000244020.021
regulation of stem cell differentiationGO:200073640.021
cellular amino acid metabolic processGO:000652070.021
small molecule metabolic processGO:0044281770.020
cell surface receptor signaling pathwayGO:00071663250.020
lateral inhibitionGO:004633110.020
rna localizationGO:000640340.020
taxisGO:00423301090.020
regulation of nucleobase containing compound metabolic processGO:00192192500.020
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.020
regulation of cellular biosynthetic processGO:00313262450.020
regulation of developmental processGO:00507932470.020
positive regulation of secretionGO:005104710.020
positive regulation of cytoskeleton organizationGO:005149530.020
organic acid metabolic processGO:0006082310.020
regulation of reactive oxygen species metabolic processGO:200037720.020
head developmentGO:00603223030.020
regulation of cellular ketone metabolic processGO:001056570.020
epithelial cell differentiationGO:00308551160.020
organelle organizationGO:00069962270.020
lipid catabolic processGO:001604240.020
synaptic transmission cholinergicGO:000727140.019
regulation of multicellular organismal developmentGO:20000262230.019
peptidyl threonine phosphorylationGO:001810710.019
cellular aromatic compound metabolic processGO:00067252950.019
post embryonic organ developmentGO:004856940.019
nuclear migrationGO:000709730.019
regulation of reproductive processGO:200024140.019
negative regulation of cellular processGO:00485232830.019
cytokinesisGO:000091030.019
oxoacid metabolic processGO:0043436310.019
hemopoiesisGO:00300971830.019
muscle organ developmentGO:00075171010.019
cellular ketone metabolic processGO:0042180110.019
cortical cytoskeleton organizationGO:003086510.019
response to endogenous stimulusGO:0009719830.019
protein complex disassemblyGO:004324110.019
positive regulation of cellular amine metabolic processGO:003324000.019
regulation of mrna processingGO:005068430.019
response to ketoneGO:190165410.019
regulation of protein import into nucleusGO:004230620.019
regulation of epithelial cell proliferationGO:005067830.019
muscle cell differentiationGO:00426921390.018
regulation of tube sizeGO:003515020.018
response to mechanical stimulusGO:0009612240.018
glucose importGO:004632320.018
nucleic acid templated transcriptionGO:00976591810.018
retina development in camera type eyeGO:00600411460.018
deathGO:00162651210.018
cell growthGO:0016049570.018
regulation of metal ion transportGO:001095940.018
antimicrobial humoral responseGO:001973020.018
phagocytosis engulfmentGO:000691110.018
determination of left right symmetryGO:00073681790.018
membrane invaginationGO:001032410.018
transportGO:00068102200.018
lipid storageGO:001991510.018
phosphorus metabolic processGO:00067931090.018
adherens junction organizationGO:003433240.018
regulation of cytoplasmic transportGO:190364940.018
cellular response to decreased oxygen levelsGO:003629410.018
regulation of apoptotic processGO:0042981980.018
regulation of multicellular organismal processGO:00512392770.018
macroautophagyGO:001623610.018
protein modification processGO:00362111000.017
programmed cell deathGO:00125011190.017
extrinsic apoptotic signaling pathwayGO:009719130.017
locomotionGO:00400113130.017
negative regulation of protein serine threonine kinase activityGO:007190120.017
symbiosis encompassing mutualism through parasitismGO:004440340.017
positive regulation of map kinase activityGO:004340630.017
regulation of cell deathGO:00109411030.017
regulation of autophagyGO:001050630.017
regulation of blood pressureGO:000821710.017
leukocyte homeostasisGO:000177620.017
cytoskeleton organizationGO:0007010960.017
response to corticosteroidGO:003196010.017
regulation of response to stimulusGO:00485832690.017
neuron projection extensionGO:1990138450.017
negative regulation of protein kinase activityGO:000646940.017
intracellular signal transductionGO:0035556850.017
cellular protein metabolic processGO:00442671290.017
behaviorGO:0007610740.017
brain developmentGO:00074202930.017
regulation of biosynthetic processGO:00098892500.017
interspecies interaction between organismsGO:004441940.016
axon extensionGO:0048675450.016
somatic muscle developmentGO:000752540.016
cellular component maintenanceGO:004395430.016
regulation of endothelial cell proliferationGO:000193610.016
sensory organ morphogenesisGO:00905962000.016
exocytosisGO:000688710.016
positive regulation of purine nucleotide catabolic processGO:003312310.016
spermatid developmentGO:000728620.016
stem cell divisionGO:001714510.016
striated muscle cell developmentGO:00550021080.016
cellular response to molecule of bacterial originGO:007121930.016
adherens junction maintenanceGO:003433420.016
viral processGO:001603210.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
negative regulation of kinase activityGO:003367340.016
regulation of signalingGO:00230512350.016
response to nutrientGO:000758430.016
cell deathGO:00082191210.016
regulation of blood vessel sizeGO:005088020.016
lamellipodium assemblyGO:003003210.016
signal transduction in absence of ligandGO:003803410.016
atp catabolic processGO:000620040.016
inner ear developmentGO:00488391260.016
regulation of growth rateGO:004000910.016
neurological system processGO:0050877620.016
cellular biosynthetic processGO:00442492860.016
regulation of purine nucleotide catabolic processGO:003312120.016
regulation of dendrite developmentGO:005077330.016
secondary metabolic processGO:001974830.016
regulation of cell communicationGO:00106462320.016
regulation of meiotic cell cycleGO:005144510.016
positive regulation of nucleotide catabolic processGO:003081310.016
regulation of gtpase activityGO:004308720.016
germ line stem cell maintenanceGO:003071820.016
positive regulation of gtp catabolic processGO:003312610.016
compound eye developmentGO:004874920.016
regulation of anatomical structure morphogenesisGO:00226031300.016
negative regulation of cytoplasmic transportGO:190365020.016
gastrulationGO:00073692080.016
positive regulation of epithelial cell proliferationGO:005067910.016
protein localization to plasma membraneGO:007265910.016
motor neuron axon guidanceGO:0008045230.016
regulation of gene expressionGO:00104682650.015
response to metal ionGO:0010038340.015
nucleoside monophosphate catabolic processGO:000912540.015
protein homooligomerizationGO:005126030.015
digestive tract morphogenesisGO:00485462310.015
protein acetylationGO:000647320.015
wound healingGO:0042060900.015
actin filament polymerizationGO:003004120.015
spermatid differentiationGO:004851520.015
regulation of response to extracellular stimulusGO:003210410.015
multi organism processGO:00517041340.015
locomotor rhythmGO:004547530.015
positive regulation of nucleoside metabolic processGO:004597910.015
regulation of glucose importGO:004632410.015
regulation of protein targetingGO:190353320.015
neuron projection guidanceGO:0097485860.015
macromolecular complex disassemblyGO:003298410.015
regulation of signal transductionGO:00099662250.015
regulation of phGO:000688530.015
axon guidanceGO:0007411860.015
response to alkaloidGO:004327920.015
b cell activationGO:004211320.015
ear developmentGO:00435831270.015
negative regulation of cytokine productionGO:000181810.015
cell substrate junction assemblyGO:000704420.015
immune system developmentGO:00025201910.015
positive regulation of immune effector processGO:000269930.015
regulation of rna metabolic processGO:00512522240.015
mechanosensory behaviorGO:000763820.015
hepaticobiliary system developmentGO:0061008980.015
alpha amino acid metabolic processGO:190160530.015
protein complex subunit organizationGO:0071822460.015
cellular response to endogenous stimulusGO:0071495680.015
negative regulation of defense responseGO:003134820.015
mononuclear cell proliferationGO:003294310.015
regulation of gtp catabolic processGO:003312420.015
sleepGO:003043110.015
regulation of erk1 and erk2 cascadeGO:007037240.015
regulation of rna biosynthetic processGO:20011412130.015
embryonic heart tube developmentGO:00350501330.014
response to uvGO:000941130.014
protein dephosphorylationGO:000647030.014
skeletal system developmentGO:00015011810.014
regulation of circadian rhythmGO:004275240.014
transcription dna templatedGO:00063511810.014
carboxylic acid metabolic processGO:0019752220.014
regulation of glucose transportGO:001082710.014
regulation of inflammatory responseGO:005072720.014
regulation of organelle assemblyGO:190211540.014
peptidyl threonine modificationGO:001821010.014
developmental programmed cell deathGO:001062340.014
regulation of protein catabolic processGO:004217610.014
ribonucleoside monophosphate catabolic processGO:000915840.014
tissue regenerationGO:0042246740.014
cellular protein modification processGO:00064641000.014
alcohol biosynthetic processGO:004616520.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
regulation of muscle contractionGO:000693730.014
regulation of molecular functionGO:0065009700.014
regulation of systemic arterial blood pressureGO:000307310.014
positive regulation of cytokine productionGO:000181920.014
response to lipidGO:0033993600.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
nucleobase containing compound biosynthetic processGO:00346542050.014
response to other organismGO:0051707970.014
urogenital system developmentGO:0001655970.014
sensory perception of smellGO:000760820.014
liver developmentGO:0001889960.014
cell junction maintenanceGO:003433120.014
lamellipodium organizationGO:009758110.014
lymphocyte proliferationGO:004665110.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
modification dependent macromolecule catabolic processGO:004363230.014
purine nucleoside monophosphate catabolic processGO:000912840.014
muscle cell developmentGO:00550011150.014
regulation of transcription dna templatedGO:00063552130.014
hematopoietic or lymphoid organ developmentGO:00485341910.013
stem cell differentiationGO:00488631170.013
positive regulation of gtpase activityGO:004354710.013
macromolecule modificationGO:00434121110.013
negative regulation of intracellular transportGO:003238730.013
rna biosynthetic processGO:00327741810.013
response to methanolGO:003398640.013
positive regulation of translationGO:004572710.013
peptidyl lysine acetylationGO:001839420.013
negative regulation of protein transportGO:005122430.013
chemosensory behaviorGO:000763510.013
cellular response to radiationGO:007147840.013
amino acid transportGO:000686520.013
meiotic cell cycle processGO:190304630.013
regulation of membrane potentialGO:0042391230.013
regulation of myotube differentiationGO:001083020.013
hormone transportGO:000991420.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
organism emergence from protective structureGO:007168440.013
regulation of organ growthGO:004662030.013
neuromast developmentGO:0048884460.013
embryonic heart tube morphogenesisGO:00031431080.013
peptide metabolic processGO:000651810.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
female sex differentiationGO:004666040.013
actin filament based movementGO:003004810.013
aromatic compound biosynthetic processGO:00194382170.013
regulation of ion transmembrane transporter activityGO:003241220.013
eye morphogenesisGO:00485921440.013
cellular protein complex disassemblyGO:004362410.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
macromolecule biosynthetic processGO:00090592270.013
response to oxygen containing compoundGO:1901700550.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
negative regulation of metabolic processGO:0009892860.012
positive regulation of lipid metabolic processGO:004583410.012
renal system developmentGO:0072001940.012
cellular protein catabolic processGO:004425740.012
regulation of protein metabolic processGO:0051246560.012
regulation of localizationGO:00328791040.012
negative regulation of catabolic processGO:000989530.012
small molecule catabolic processGO:004428230.012
positive regulation of cell activationGO:005086710.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
regulation of cell substrate adhesionGO:001081010.012
internal peptidyl lysine acetylationGO:001839320.012
regulation of programmed cell deathGO:00430671010.012
rna 3 end processingGO:003112320.012
regulation of synaptic plasticityGO:004816710.012
regulation of transporter activityGO:003240920.012
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
myotube differentiationGO:0014902450.012
organelle assemblyGO:00709251100.012
positive regulation of striated muscle tissue developmentGO:004584410.012
protein depolymerizationGO:005126110.012
lateral line developmentGO:0048882660.012
regulation of neural precursor cell proliferationGO:200017730.012
negative regulation of stem cell differentiationGO:200073720.012
regulation of cellular component movementGO:0051270550.012
regulation of response to biotic stimulusGO:000283120.012
neurotransmitter transportGO:000683620.012
response to nicotineGO:003509420.012
regulation of protein bindingGO:004339330.012
microtubule polymerization or depolymerizationGO:003110930.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
regulation of macromolecule biosynthetic processGO:00105562250.012
cellular response to methanolGO:007140540.012
monoamine transportGO:001584410.012
positive regulation of synapse assemblyGO:005196510.012
somatic stem cell maintenanceGO:003501910.012
internal protein amino acid acetylationGO:000647520.012
rho protein signal transductionGO:000726650.012
hormone secretionGO:004687920.012
regulation of cellular component organizationGO:0051128860.012
heart morphogenesisGO:00030071560.012
ubiquitin dependent protein catabolic processGO:000651130.012
cellular amide metabolic processGO:004360340.012
striated muscle cell differentiationGO:00511461290.012
response to biotic stimulusGO:0009607970.012
intracellular mrna localizationGO:000829810.011
response to hormoneGO:0009725480.011
centrosome organizationGO:005129710.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
protein acylationGO:004354330.011
determination of heart left right asymmetryGO:00613711170.011
modification dependent protein catabolic processGO:001994130.011
nuclear exportGO:005116810.011
positive regulation of jnk cascadeGO:004633030.011
cell migration involved in gastrulationGO:0042074790.011

pls3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.056
nervous system diseaseDOID:86300.022
immune system diseaseDOID:291400.019
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.017
cardiovascular system diseaseDOID:128700.015
musculoskeletal system diseaseDOID:1700.014
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012