Danio rerio

0 known processes

ern1

endoplasmic reticulum to nucleus signaling 1

(Aliases: MGC109932,zgc:109932)

ern1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.072
proteasomal protein catabolic processGO:001049820.066
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.061
cellular protein catabolic processGO:004425740.054
positive regulation of cellular component biogenesisGO:004408930.051
gene expressionGO:00104672520.051
negative regulation of nuclear divisionGO:005178430.049
positive regulation of transportGO:005105020.048
response to stressGO:00069502630.048
modification dependent protein catabolic processGO:001994130.048
regulation of protein complex assemblyGO:004325430.047
ubiquitin dependent protein catabolic processGO:000651130.044
rna metabolic processGO:00160702190.042
meiotic nuclear divisionGO:000712640.040
regulation of establishment of protein localizationGO:007020140.039
modification dependent macromolecule catabolic processGO:004363230.038
proteolysis involved in cellular protein catabolic processGO:005160330.038
sequestering of metal ionGO:005123830.036
negative regulation of mitosisGO:004583930.036
agingGO:000756820.036
female gonad developmentGO:000858540.034
female sex differentiationGO:004666040.033
cellular response to nutrient levelsGO:003166920.033
negative regulation of protein phosphorylationGO:000193340.032
positive regulation of protein complex assemblyGO:003133420.032
maintenance of locationGO:005123540.032
mitochondrion organizationGO:000700540.031
regulation of cellular metabolic processGO:00313233200.031
establishment of protein localization to organelleGO:007259440.031
negative regulation of cellular processGO:00485232830.030
regulation of protein catabolic processGO:004217610.030
regulation of cytoplasmic transportGO:190364940.030
regulation of cellular ketone metabolic processGO:001056570.029
positive regulation of secretion by cellGO:190353210.029
regulation of sequestering of calcium ionGO:005128240.028
sequestering of calcium ionGO:005120830.028
signal transductionGO:00071654550.028
cell surface receptor signaling pathwayGO:00071663250.028
negative regulation of sequestering of calcium ionGO:005128340.028
protein importGO:001703830.028
nucleobase containing compound metabolic processGO:00061392740.027
regulation of metal ion transportGO:001095940.027
cellular nitrogen compound biosynthetic processGO:00442712180.027
regulation of protein transportGO:005122330.027
regulation of macromolecule metabolic processGO:00602553170.027
extrinsic apoptotic signaling pathwayGO:009719130.026
positive regulation of cell cycleGO:004578730.026
regulation of extrinsic apoptotic signaling pathwayGO:200123630.026
single organism nuclear importGO:190259330.026
cellular macromolecule metabolic processGO:00442603910.026
rna localizationGO:000640340.026
cellular nitrogen compound metabolic processGO:00346412900.026
release of sequestered calcium ion into cytosolGO:005120930.025
positive regulation of cytosolic calcium ion concentrationGO:000720440.025
protein metabolic processGO:00195381830.025
nucleic acid metabolic processGO:00903042440.024
cellular component assemblyGO:00226071700.024
embryonic organ developmentGO:00485683810.024
leukocyte proliferationGO:007066110.023
cell migrationGO:00164772370.023
erk1 and erk2 cascadeGO:007037140.023
regulation of erk1 and erk2 cascadeGO:007037240.023
response to chemicalGO:00422213200.023
phagocytosisGO:000690930.023
nucleocytoplasmic transportGO:000691340.023
response to organic substanceGO:00100331530.023
positive regulation of secretionGO:005104710.023
regulation of metabolic processGO:00192223590.023
regulation of macromolecule biosynthetic processGO:00105562250.023
response to topologically incorrect proteinGO:003596620.022
amine metabolic processGO:000930820.022
autophagyGO:000691440.022
negative regulation of protein transportGO:005122430.022
biosynthetic processGO:00090582940.022
mitochondrial transportGO:000683920.022
cellular component movementGO:00069283350.022
organic cyclic compound metabolic processGO:19013603010.022
cellular amine metabolic processGO:004410620.022
regulation of nitrogen compound metabolic processGO:00511712510.022
response to uvGO:000941130.022
cellular response to biotic stimulusGO:007121630.022
mononuclear cell proliferationGO:003294310.021
regulation of rna biosynthetic processGO:20011412130.021
morphogenesis of an epitheliumGO:00020093330.021
cytokinesisGO:000091030.021
cellular amino acid metabolic processGO:000652070.021
heterocycle biosynthetic processGO:00181302150.021
cellular response to extracellular stimulusGO:003166820.021
regulation of meiotic cell cycleGO:005144510.021
membrane fusionGO:006102520.021
regulation of cellular amine metabolic processGO:003323800.021
g1 s transition of mitotic cell cycleGO:000008210.020
positive regulation of catabolic processGO:000989640.020
regulation of biosynthetic processGO:00098892500.020
regulation of gene expressionGO:00104682650.020
calcium ion transport into cytosolGO:006040230.020
regulation of multicellular organism growthGO:004001440.020
cellular response to external stimulusGO:007149620.020
nitrogen compound metabolic processGO:00068073190.020
regulation of cytokine productionGO:000181730.020
cellular response to molecule of bacterial originGO:007121930.020
digestive system developmentGO:00551232890.020
multicellular organism growthGO:003526440.020
regulation of biological qualityGO:00650082630.020
organic substance biosynthetic processGO:19015762890.020
regulation of protein localization to nucleusGO:190018020.020
heterocycle metabolic processGO:00464832900.020
tissue remodelingGO:004877140.020
regulation of reactive oxygen species metabolic processGO:200037720.020
regulation of synapse organizationGO:005080730.020
regulation of protein import into nucleusGO:004230620.020
protein secretionGO:000930610.019
cellular component disassemblyGO:002241110.019
organelle organizationGO:00069962270.019
development of primary female sexual characteristicsGO:004654540.019
blood vessel developmentGO:00015682460.019
vasculature developmentGO:00019442780.019
lipid storageGO:001991510.019
cellular ketone metabolic processGO:0042180110.019
regulation of wound healingGO:006104120.019
regulation of primary metabolic processGO:00800903110.019
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.019
tube morphogenesisGO:00352393490.019
cellular component biogenesisGO:00440851780.019
protein targeting to nucleusGO:004474430.018
positive regulation of chromatin modificationGO:190331010.018
embryo development ending in birth or egg hatchingGO:00097922710.018
regulation of cellular amino acid metabolic processGO:000652100.018
cellular response to starvationGO:000926710.018
synaptic growth at neuromuscular junctionGO:005112420.018
nucleic acid templated transcriptionGO:00976591810.018
nuclear transportGO:005116940.018
regulation of cellular macromolecule biosynthetic processGO:20001122220.018
nucleobase containing compound biosynthetic processGO:00346542050.018
neuron differentiationGO:00301823530.018
regulation of calcium ion transportGO:005192420.018
positive regulation of cellular processGO:00485222010.018
gtp catabolic processGO:000618420.018
protein dephosphorylationGO:000647030.018
regulation of transcription dna templatedGO:00063552130.018
protein import into nucleusGO:000660630.018
cellular aromatic compound metabolic processGO:00067252950.018
cell cycle g1 s phase transitionGO:004484310.017
protein localization to nucleusGO:003450430.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
negative regulation of cytoplasmic transportGO:190365020.017
stem cell maintenanceGO:001982740.017
chordate embryonic developmentGO:00430092710.017
double strand break repairGO:000630230.017
regulation of protein targetingGO:190353320.017
positive regulation of cytoskeleton organizationGO:005149530.017
negative regulation of biological processGO:00485193040.017
positive regulation of dna metabolic processGO:005105410.017
positive regulation of cellular catabolic processGO:003133130.017
regulation of bindingGO:005109830.017
regulation of nucleocytoplasmic transportGO:004682220.017
lymphocyte proliferationGO:004665110.017
atp catabolic processGO:000620040.017
internal peptidyl lysine acetylationGO:001839320.017
intracellular mrna localizationGO:000829810.017
regulation of rna metabolic processGO:00512522240.016
negative regulation of catabolic processGO:000989530.016
neurotransmitter transportGO:000683620.016
digestive tract developmentGO:00485652650.016
ovulation cycleGO:004269820.016
organelle fusionGO:004828430.016
ovulation cycle processGO:002260220.016
response to unfolded proteinGO:000698620.016
single organism metabolic processGO:00447102170.016
positive regulation of purine nucleotide catabolic processGO:003312310.016
exocytosisGO:000688710.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
peptidyl serine phosphorylationGO:001810510.016
cellular response to organic substanceGO:00713101050.016
ribonucleoside monophosphate catabolic processGO:000915840.016
positive regulation of biological processGO:00485182530.016
regulation of cell activationGO:005086510.016
rna biosynthetic processGO:00327741810.016
peptidyl lysine acetylationGO:001839420.016
negative regulation of kinase activityGO:003367340.016
regulation of mitochondrion organizationGO:001082110.016
cellular response to oxygen levelsGO:007145310.016
protein acetylationGO:000647320.016
spermatid differentiationGO:004851520.016
regulation of purine nucleotide catabolic processGO:003312120.016
rna transportGO:005065820.016
negative regulation of metabolic processGO:0009892860.016
nuclear importGO:005117030.016
regulation of synapse assemblyGO:005196330.016
purine nucleoside monophosphate catabolic processGO:000912840.015
nuclear exportGO:005116810.015
organelle assemblyGO:00709251100.015
i kappab kinase nf kappab signalingGO:000724940.015
cellular response to light stimulusGO:007148240.015
central nervous system developmentGO:00074173870.015
nucleic acid transportGO:005065720.015
regulation of protein ubiquitinationGO:003139630.015
system processGO:00030081850.015
single organism localizationGO:19025782250.015
establishment of rna localizationGO:005123630.015
translational initiationGO:000641330.015
inositol lipid mediated signalingGO:004801720.015
negative regulation of protein serine threonine kinase activityGO:007190120.015
single organism membrane fusionGO:004480120.015
cellular response to unfolded proteinGO:003462020.015
locomotionGO:00400113130.015
guanosine containing compound catabolic processGO:190106920.015
negative regulation of protein kinase activityGO:000646940.015
endosomal transportGO:001619720.014
regulation of chromosome segregationGO:005198310.014
localization of cellGO:00516742440.014
endoplasmic reticulum unfolded protein responseGO:003096820.014
positive regulation of chromosome organizationGO:200125210.014
peptidyl serine modificationGO:001820920.014
guanosine containing compound metabolic processGO:190106840.014
neuron neuron synaptic transmissionGO:000727010.014
cellular response to topologically incorrect proteinGO:003596720.014
aromatic compound biosynthetic processGO:00194382170.014
cell projection morphogenesisGO:00488582440.014
antimicrobial humoral responseGO:001973020.014
transcription dna templatedGO:00063511810.014
meiotic cell cycle processGO:190304630.014
negative regulation of map kinase activityGO:004340720.014
regulation of cellular protein catabolic processGO:190336210.014
negative regulation of mapk cascadeGO:004340940.014
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.014
mitotic dna integrity checkpointGO:004477440.014
interspecies interaction between organismsGO:004441940.014
response to antibioticGO:004667710.014
nucleobase containing compound transportGO:001593120.014
mrna stabilizationGO:004825540.014
developmental growthGO:00485891660.014
ameboidal type cell migrationGO:00016671430.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
positive regulation of cytokine productionGO:000181920.014
regulation of inflammatory responseGO:005072720.014
post embryonic organ developmentGO:004856940.014
cellular modified amino acid metabolic processGO:000657530.014
developmental programmed cell deathGO:001062340.014
establishment of localizationGO:00512342440.014
peptide metabolic processGO:000651810.014
response to abiotic stimulusGO:00096281220.013
cell motilityGO:00488702440.013
chemosensory behaviorGO:000763510.013
homeostatic processGO:00425921420.013
oxoacid metabolic processGO:0043436310.013
gtp metabolic processGO:004603940.013
negative regulation of protein import into nucleusGO:004230820.013
regulation of nucleoside metabolic processGO:000911820.013
single organism organelle organizationGO:19025891990.013
regulation of reproductive processGO:200024140.013
mitotic dna damage checkpointGO:004477340.013
cellular biosynthetic processGO:00442492860.013
positive regulation of cell activationGO:005086710.013
protein modification processGO:00362111000.013
regulation of signal transductionGO:00099662250.013
regulation of epithelial cell proliferationGO:005067830.013
regulation of transporter activityGO:003240920.013
macromolecule modificationGO:00434121110.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
embryonic organ morphogenesisGO:00485622740.013
b cell activationGO:004211320.013
regulation of organelle assemblyGO:190211540.013
cellular carbohydrate metabolic processGO:004426240.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
regulation of localizationGO:00328791040.013
cellular macromolecule biosynthetic processGO:00346452240.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
protein polymerizationGO:005125840.013
internal protein amino acid acetylationGO:000647520.013
transcription from rna polymerase ii promoterGO:0006366800.013
fertilizationGO:000956630.013
negative regulation of nucleocytoplasmic transportGO:004682320.012
negative regulation of intracellular transportGO:003238730.012
regulation of gtpase activityGO:004308720.012
regulation of stem cell proliferationGO:007209120.012
organonitrogen compound metabolic processGO:1901564740.012
er nucleus signaling pathwayGO:000698420.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
organic acid metabolic processGO:0006082310.012
mesenchymal cell differentiationGO:0048762870.012
rna modificationGO:000945120.012
cell matrix adhesionGO:000716040.012
rna polyadenylationGO:004363120.012
cellular protein metabolic processGO:00442671290.012
regulation of synaptic plasticityGO:004816710.012
regulation of nucleotide catabolic processGO:003081120.012
negative regulation of secretionGO:005104820.012
neuroblast proliferationGO:000740520.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
heart developmentGO:00075073130.012
axon developmentGO:00615641660.012
negative regulation of signal transductionGO:0009968940.012
negative regulation of cellular metabolic processGO:0031324770.012
spindle assemblyGO:005122520.012
phosphatidylinositol mediated signalingGO:004801520.012
cellular response to decreased oxygen levelsGO:003629410.012
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.012
generation of neuronsGO:00486993850.012
negative regulation of defense responseGO:003134820.012
regulation of protein polymerizationGO:003227120.012
cell substrate adhesionGO:003158940.012
blood vessel morphogenesisGO:00485142160.012
positive regulation of jnk cascadeGO:004633030.012
nucleoside monophosphate catabolic processGO:000912540.012
stem cell proliferationGO:007208940.012
positive regulation of cell divisionGO:005178120.012
negative regulation of epithelial cell proliferationGO:005068010.012
cellular response to chemical stimulusGO:00708871570.012
negative regulation of cellular catabolic processGO:003133030.012
cellular amide metabolic processGO:004360340.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
positive regulation of protein polymerizationGO:003227320.012
negative regulation of signalingGO:0023057960.012
organic cyclic compound biosynthetic processGO:19013622230.012
regulation of dna replicationGO:000627530.012
protein localization to plasma membraneGO:007265910.012
cell part morphogenesisGO:00329902460.012
positive regulation of histone modificationGO:003105810.012
regulation of intracellular protein transportGO:003315730.011
negative regulation of cytokine productionGO:000181810.011
regulation of dendrite morphogenesisGO:004881430.011
cell morphogenesisGO:00009022890.011
protein homooligomerizationGO:005126030.011
regulation of developmental processGO:00507932470.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
regulation of response to stimulusGO:00485832690.011
macromolecule biosynthetic processGO:00090592270.011
negative regulation of gene expressionGO:0010629650.011
regulation of signalingGO:00230512350.011
regulation of autophagyGO:001050630.011
rna stabilizationGO:004348940.011
regulation of multicellular organismal processGO:00512392770.011
protein heterooligomerizationGO:005129110.011
protein acylationGO:004354330.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.011
regulation of cellular component organizationGO:0051128860.011
cellular response to hypoxiaGO:007145610.011
regulation of response to biotic stimulusGO:000283120.011
stem cell divisionGO:001714510.011
negative regulation of response to stimulusGO:00485851040.011
regulation of protein metabolic processGO:0051246560.011
mrna transportGO:005102820.011
cognitionGO:005089010.011
cytoplasm organizationGO:000702840.011
protein polyubiquitinationGO:000020940.011
cell cycle arrestGO:000705010.011
negative regulation of intracellular protein transportGO:009031730.011
cytosolic calcium ion transportGO:006040130.011
neurotransmitter secretionGO:000726920.011
positive regulation of cellular amine metabolic processGO:003324000.011
positive regulation of nucleotide catabolic processGO:003081310.011
regulation of ion transmembrane transporter activityGO:003241220.011
cell projection organizationGO:00300302840.011
eye developmentGO:00016542770.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.011
regulation of mrna processingGO:005068430.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
regulation of stem cell differentiationGO:200073640.011
double strand break repair via homologous recombinationGO:000072410.011
immune system processGO:00023762410.011
adherens junction organizationGO:003433240.011
negative regulation of protein complex assemblyGO:003133310.011
compound eye developmentGO:004874920.011
dna templated transcription elongationGO:000635430.011
carboxylic acid metabolic processGO:0019752220.010
regulation of cellular biosynthetic processGO:00313262450.010
secondary metabolic processGO:001974830.010
positive regulation of lymphocyte mediated immunityGO:000270810.010
adult behaviorGO:003053420.010
negative regulation of secretion by cellGO:190353120.010
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.010
signal transduction in absence of ligandGO:003803410.010
regulation of peptidyl tyrosine phosphorylationGO:005073010.010
negative regulation of macromolecule metabolic processGO:0010605760.010
synaptic vesicle localizationGO:009747910.010
macromolecular complex disassemblyGO:003298410.010
positive regulation of immune effector processGO:000269930.010
positive regulation of nucleoside metabolic processGO:004597910.010
regulation of exocytosisGO:001715710.010
ncrna catabolic processGO:003466110.010
xenobiotic metabolic processGO:000680540.010
response to woundingGO:00096111160.010
germ line stem cell maintenanceGO:003071820.010
transportGO:00068102200.010
phosphate containing compound metabolic processGO:00067961080.010

ern1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
disease of metabolismDOID:001466700.021
nervous system diseaseDOID:86300.019
immune system diseaseDOID:291400.019
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
musculoskeletal system diseaseDOID:1700.015
organ system cancerDOID:005068600.014
cardiovascular system diseaseDOID:128700.012
inherited metabolic disorderDOID:65500.011
muscular diseaseDOID:008000000.010