Danio rerio

24 known processes

mipa

major intrinsic protein of lens fiber a

(Aliases: mip1,zgc:100858)

mipa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
camera type eye developmentGO:00430102220.445
sensory organ developmentGO:00074233930.176
ion transportGO:00068111140.162
Zebrafish Rat
regulation of sequestering of calcium ionGO:005128240.154
positive regulation of wound healingGO:009030310.152
regulation of wound healingGO:006104120.128
eye developmentGO:00016542770.116
myotube differentiationGO:0014902450.105
head developmentGO:00603223030.099
sequestering of metal ionGO:005123830.094
myotube cell developmentGO:0014904350.084
i kappab kinase nf kappab signalingGO:000724940.084
positive regulation of cellular processGO:00485222010.084
response to stressGO:00069502630.083
maintenance of locationGO:005123540.081
nucleobase containing compound metabolic processGO:00061392740.080
sensory perception of light stimulusGO:0050953190.078
Mouse
single organism membrane fusionGO:004480120.077
regulation of nitrogen compound metabolic processGO:00511712510.075
larval developmentGO:000216420.074
cellular macromolecule metabolic processGO:00442603910.074
guanosine containing compound metabolic processGO:190106840.071
cellular aromatic compound metabolic processGO:00067252950.067
mitochondrion organizationGO:000700540.064
carbon dioxide transportGO:001567030.064
Zebrafish
gene expressionGO:00104672520.064
regulation of metal ion transportGO:001095940.063
response to external stimulusGO:00096052640.063
sensory organ morphogenesisGO:00905962000.062
regulation of i kappab kinase nf kappab signalingGO:004312240.062
regulation of cellular metabolic processGO:00313233200.061
response to inorganic substanceGO:0010035380.058
muscle fiber developmentGO:0048747520.058
regulation of primary metabolic processGO:00800903110.057
regulation of calcium ion transportGO:005192420.056
regulation of transcription dna templatedGO:00063552130.056
inorganic ion transmembrane transportGO:0098660570.055
Zebrafish
organic substance biosynthetic processGO:19015762890.054
positive regulation of response to woundingGO:190303650.053
eye morphogenesisGO:00485921440.052
central nervous system developmentGO:00074173870.052
positive regulation of catabolic processGO:000989640.051
cellular nitrogen compound metabolic processGO:00346412900.051
muscle structure developmentGO:00610611960.051
regulation of macromolecule metabolic processGO:00602553170.051
cytosolic calcium ion transportGO:006040130.050
positive regulation of cell activationGO:005086710.050
nitrogen compound metabolic processGO:00068073190.050
regulation of cell activationGO:005086510.049
sequestering of calcium ionGO:005120830.049
negative regulation of cellular processGO:00485232830.048
extrinsic apoptotic signaling pathwayGO:009719130.046
heterocycle biosynthetic processGO:00181302150.046
agingGO:000756820.045
system processGO:00030081850.045
Mouse
retina development in camera type eyeGO:00600411460.045
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.044
lens fiber cell developmentGO:007030730.044
lens development in camera type eyeGO:0002088220.044
organic cyclic compound metabolic processGO:19013603010.044
regulation of cytoplasmic transportGO:190364940.044
negative regulation of sequestering of calcium ionGO:005128340.044
release of sequestered calcium ion into cytosolGO:005120930.042
regulation of cysteine type endopeptidase activityGO:2000116210.042
striated muscle tissue developmentGO:00147061100.042
rna metabolic processGO:00160702190.041
regulation of cellular macromolecule biosynthetic processGO:20001122220.041
generation of neuronsGO:00486993850.041
blood vessel morphogenesisGO:00485142160.041
brain developmentGO:00074202930.041
developmental programmed cell deathGO:001062340.041
nucleic acid metabolic processGO:00903042440.040
cation transportGO:0006812810.040
Zebrafish
response to chemicalGO:00422213200.040
regenerationGO:0031099910.040
response to woundingGO:00096111160.040
regulation of cell deathGO:00109411030.040
regulation of metabolic processGO:00192223590.039
calcium ion transport into cytosolGO:006040230.039
organic cyclic compound biosynthetic processGO:19013622230.039
fluid transportGO:0042044170.039
positive regulation of biological processGO:00485182530.039
regulation of multicellular organismal processGO:00512392770.039
regulation of organ growthGO:004662030.038
regulation of proteolysisGO:0030162240.037
regulation of apoptotic processGO:0042981980.037
positive regulation of transportGO:005105020.037
establishment of localizationGO:00512342440.037
positive regulation of cellular catabolic processGO:003133130.037
cellular response to external stimulusGO:007149620.036
signal transductionGO:00071654550.036
visual perceptionGO:0007601170.035
Mouse
multicellular organism growthGO:003526440.035
cellular biosynthetic processGO:00442492860.035
response to metal ionGO:0010038340.034
phagocytosisGO:000690930.034
response to abiotic stimulusGO:00096281220.033
organelle organizationGO:00069962270.033
cellular component assemblyGO:00226071700.033
gas transportGO:001566930.033
Zebrafish
regulation of multicellular organism growthGO:004001440.033
guanosine containing compound catabolic processGO:190106920.032
angiogenesisGO:00015251580.032
negative regulation of biological processGO:00485193040.032
gtp metabolic processGO:004603940.031
gtp catabolic processGO:000618420.031
wound healingGO:0042060900.031
ion transmembrane transportGO:0034220910.031
Zebrafish
regulation of developmental processGO:00507932470.031
female gonad developmentGO:000858540.031
regulation of rna biosynthetic processGO:20011412130.031
regulation of cellular biosynthetic processGO:00313262450.030
blood vessel developmentGO:00015682460.030
deathGO:00162651210.030
positive regulation of dna metabolic processGO:005105410.030
positive regulation of cellular component biogenesisGO:004408930.029
aromatic compound biosynthetic processGO:00194382170.029
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.029
embryonic organ developmentGO:00485683810.029
nucleobase containing compound biosynthetic processGO:00346542050.028
negative regulation of biosynthetic processGO:0009890550.028
muscle organ developmentGO:00075171010.028
muscle cell differentiationGO:00426921390.028
transportGO:00068102200.028
inorganic anion transportGO:0015698250.027
Zebrafish
regulation of multicellular organismal developmentGO:20000262230.027
positive regulation of proteolysisGO:0045862100.027
heterocycle metabolic processGO:00464832900.027
regulation of macromolecule biosynthetic processGO:00105562250.027
rna biosynthetic processGO:00327741810.027
stem cell divisionGO:001714510.027
regulation of extrinsic apoptotic signaling pathwayGO:200123630.027
regulation of cell developmentGO:00602841000.027
developmental growthGO:00485891660.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
regulation of nucleotide catabolic processGO:003081120.026
organelle assemblyGO:00709251100.026
purine nucleoside monophosphate catabolic processGO:000912840.026
chordate embryonic developmentGO:00430092710.026
cellular macromolecule biosynthetic processGO:00346452240.025
skeletal muscle organ developmentGO:0060538780.025
apoptotic process involved in developmentGO:190274220.025
transcription dna templatedGO:00063511810.025
regulation of gene expressionGO:00104682650.025
vasculature developmentGO:00019442780.025
single organism localizationGO:19025782250.025
organelle fusionGO:004828430.025
single organism metabolic processGO:00447102170.024
regulation of skeletal muscle fiber developmentGO:004874220.024
transmembrane transportGO:00550851200.024
regulation of biosynthetic processGO:00098892500.024
protein metabolic processGO:00195381830.024
regulation of cell substrate adhesionGO:001081010.024
regulation of nucleic acid templated transcriptionGO:19035062130.024
anion transportGO:0006820380.024
Zebrafish Rat
neurological system processGO:0050877620.024
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.023
neuron differentiationGO:00301823530.023
stem cell proliferationGO:007208940.023
muscle cell developmentGO:00550011150.023
cell morphogenesisGO:00009022890.023
tissue remodelingGO:004877140.023
regionalizationGO:00030022740.023
regulation of response to stimulusGO:00485832690.023
atp catabolic processGO:000620040.023
positive regulation of cytosolic calcium ion concentrationGO:000720440.023
regulation of myotube differentiationGO:001083020.023
macromolecule biosynthetic processGO:00090592270.023
regulation of cellular protein metabolic processGO:0032268520.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
modification dependent macromolecule catabolic processGO:004363230.022
cellular protein catabolic processGO:004425740.022
apoptotic process involved in morphogenesisGO:006056120.022
post embryonic organ developmentGO:004856940.022
regulation of heart growthGO:006042020.022
regulation of protein localization to nucleusGO:190018020.022
regulation of protein complex assemblyGO:004325430.021
regulation of programmed cell deathGO:00430671010.021
morphogenesis of an epitheliumGO:00020093330.021
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.021
purine ribonucleoside monophosphate catabolic processGO:000916940.021
regulation of nucleoside metabolic processGO:000911820.021
cell substrate adhesionGO:003158940.021
regulation of filopodium assemblyGO:005148920.021
regulation of cellular amine metabolic processGO:003323800.021
protein complex disassemblyGO:004324110.021
apoptotic processGO:00069151160.021
ubiquitin dependent protein catabolic processGO:000651130.021
striated muscle cell developmentGO:00550021080.021
astrocyte differentiationGO:004870810.021
muscle tissue developmentGO:00605371100.021
regulation of biological qualityGO:00650082630.021
ribonucleoside monophosphate catabolic processGO:000915840.021
regulation of sequence specific dna binding transcription factor activityGO:005109090.021
epithelial cell differentiationGO:00308551160.020
cell deathGO:00082191210.020
negative regulation of metabolic processGO:0009892860.020
modification dependent protein catabolic processGO:001994130.020
protein homooligomerizationGO:005126030.020
regulation of cellular amino acid metabolic processGO:000652100.020
ammonium transmembrane transportGO:007248820.020
Zebrafish
programmed cell deathGO:00125011190.020
skeletal muscle tissue developmentGO:0007519670.020
regulation of protein ubiquitinationGO:003139630.020
cellular response to extracellular stimulusGO:003166820.020
response to cadmium ionGO:0046686140.020
carboxylic acid metabolic processGO:0019752220.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
development of primary female sexual characteristicsGO:004654540.020
membrane fusionGO:006102520.020
regulation of protein catabolic processGO:004217610.019
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.019
protein localization to nucleusGO:003450430.019
camera type eye morphogenesisGO:00485931080.019
actin filament based movementGO:003004810.019
regulation of rna metabolic processGO:00512522240.019
negative regulation of apoptotic processGO:0043066550.019
response to hydrogen peroxideGO:004254230.019
stem cell differentiationGO:00488631170.019
signal transduction in absence of ligandGO:003803410.019
positive regulation of cytoskeleton organizationGO:005149530.019
cellular response to nutrient levelsGO:003166920.019
neuron projection regenerationGO:0031102160.019
protein importGO:001703830.019
positive regulation of nitrogen compound metabolic processGO:0051173690.018
metal ion transportGO:0030001580.018
regulation of endopeptidase activityGO:0052548230.018
cytokinesisGO:000091030.018
cellular component morphogenesisGO:00329893360.018
female sex differentiationGO:004666040.018
regulation of peptidase activityGO:0052547230.018
regulation of cell differentiationGO:00455951420.017
synaptic growth at neuromuscular junctionGO:005112420.017
positive regulation of lipid metabolic processGO:004583410.017
endodermal cell fate determinationGO:000749320.017
negative regulation of cellular biosynthetic processGO:0031327550.017
positive regulation of cell cycleGO:004578730.017
cell killingGO:000190620.017
cellular amino acid metabolic processGO:000652070.017
negative regulation of programmed cell deathGO:0043069580.017
striated muscle cell differentiationGO:00511461290.017
lateral line developmentGO:0048882660.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
regulation of skeletal muscle tissue developmentGO:004864140.016
regulation of purine nucleotide catabolic processGO:003312120.016
amide transportGO:0042886120.016
Zebrafish
negative regulation of macromolecule metabolic processGO:0010605760.016
macromolecular complex disassemblyGO:003298410.016
positive regulation of protein complex assemblyGO:003133420.016
b cell activationGO:004211320.016
monovalent inorganic cation transportGO:0015672420.015
Zebrafish
regulation of stem cell differentiationGO:200073640.015
heart developmentGO:00075073130.015
cell junction maintenanceGO:003433120.015
negative regulation of mapk cascadeGO:004340940.015
positive regulation of cell deathGO:0010942290.015
macromolecule modificationGO:00434121110.015
neuron developmentGO:00486662620.015
tissue regenerationGO:0042246740.015
embryo development ending in birth or egg hatchingGO:00097922710.015
meiotic nuclear divisionGO:000712640.015
cellular response to stressGO:0033554620.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
negative regulation of gene expressionGO:0010629650.015
negative regulation of nucleobase containing compound metabolic processGO:0045934590.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
adult behaviorGO:003053420.015
cellular ketone metabolic processGO:0042180110.015
negative regulation of cellular metabolic processGO:0031324770.015
response to xenobiotic stimulusGO:0009410450.015
proteasomal protein catabolic processGO:001049820.015
negative regulation of peptidase activityGO:0010466100.015
regulation of protein metabolic processGO:0051246560.015
regulation of mitochondrion organizationGO:001082110.015
dna catabolic processGO:000630810.015
regulation of signal transductionGO:00099662250.015
ion homeostasisGO:0050801410.015
immune system processGO:00023762410.014
positive regulation of macromolecule biosynthetic processGO:0010557590.014
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.014
multicellular organismal metabolic processGO:004423620.014
response to salt stressGO:0009651100.014
actin mediated cell contractionGO:007025210.014
cell projection morphogenesisGO:00488582440.014
neuroblast differentiationGO:001401610.014
cellular response to chemical stimulusGO:00708871570.014
cell morphogenesis involved in differentiationGO:00009041950.014
positive regulation of neuron deathGO:190121610.014
embryonic limb morphogenesisGO:003032620.014
cell surface receptor signaling pathwayGO:00071663250.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
insulin like growth factor receptor signaling pathwayGO:004800940.014
liver developmentGO:0001889960.014
negative regulation of protein phosphorylationGO:000193340.014
regulation of blood pressureGO:000821710.014
cellular component biogenesisGO:00440851780.014
protein modification processGO:00362111000.013
positive regulation of cellular amine metabolic processGO:003324000.013
inorganic cation transmembrane transportGO:0098662500.013
Zebrafish
positive regulation of purine nucleotide catabolic processGO:003312310.013
cellular localizationGO:0051641970.013
cell matrix adhesionGO:000716040.013
membrane invaginationGO:001032410.013
regulation of cell killingGO:003134120.013
biosynthetic processGO:00090582940.013
regulation of molecular functionGO:0065009700.013
regulation of cell shapeGO:000836010.013
homeostatic processGO:00425921420.013
positive regulation of stress activated mapk cascadeGO:003287430.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
immune system developmentGO:00025201910.013
autophagyGO:000691440.013
regulation of cellular protein catabolic processGO:190336210.013
phosphatidylinositol mediated signalingGO:004801520.013
response to external biotic stimulusGO:0043207970.013
melanin metabolic processGO:000658220.013
gland developmentGO:00487321430.013
regulation of cell projection assemblyGO:006049140.013
response to hexoseGO:000974630.013
pigmentationGO:0043473850.013
response to organic substanceGO:00100331530.013
sensory perceptionGO:0007600390.013
Mouse
somatic muscle developmentGO:000752540.013
response to carbohydrateGO:000974330.012
organic acid metabolic processGO:0006082310.012
single organism organelle organizationGO:19025891990.012
cellular amine metabolic processGO:004410620.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
negative regulation of dna metabolic processGO:005105340.012
positive regulation of metabolic processGO:00098931080.012
regulation of cell communicationGO:00106462320.012
internal peptidyl lysine acetylationGO:001839320.012
response to biotic stimulusGO:0009607970.012
inner ear developmentGO:00488391260.012
cellular component assembly involved in morphogenesisGO:00109271070.012
negative regulation of endopeptidase activityGO:0010951100.012
actomyosin structure organizationGO:0031032530.012
cellular response to starvationGO:000926710.012
regulation of gtpase activityGO:004308720.012
secondary metabolic processGO:001974830.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
cellular response to xenobiotic stimulusGO:0071466350.012
amine metabolic processGO:000930820.012
positive regulation of macromolecule metabolic processGO:0010604930.012
cellular component disassemblyGO:002241110.012
alcohol biosynthetic processGO:004616520.012
cellular protein modification processGO:00064641000.012
positive regulation of protein polymerizationGO:003227320.012
epithelial tube morphogenesisGO:00605621480.012
phosphate containing compound metabolic processGO:00067961080.012
regulation of reactive oxygen species metabolic processGO:200037720.012
phagocytosis engulfmentGO:000691110.012
positive regulation of cellular metabolic processGO:0031325940.011
positive regulation of transcription dna templatedGO:0045893570.011
rna localizationGO:000640340.011
positive regulation of nucleotide catabolic processGO:003081310.011
superoxide metabolic processGO:000680120.011
intracellular signal transductionGO:0035556850.011
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.011
cellular response to radiationGO:007147840.011
nucleoside monophosphate catabolic processGO:000912540.011
neuroblast proliferationGO:000740520.011
positive regulation of developmental processGO:0051094500.011
protein localization to plasma membraneGO:007265910.011
glial cell migrationGO:000834730.011
glial cell differentiationGO:0010001420.011
regulation of epithelial cell proliferationGO:005067830.011
cellular response to abiotic stimulusGO:007121440.011
gliogenesisGO:0042063450.011
regulation of cell matrix adhesionGO:000195210.011
dna metabolic processGO:0006259270.011
positive regulation of chromosome organizationGO:200125210.011
inositol lipid mediated signalingGO:004801720.011
positive regulation of stem cell proliferationGO:200064810.011
cytokinetic processGO:003250620.011
response to amino acidGO:004320020.011
regulation of growthGO:0040008420.011
cytoskeleton dependent cytokinesisGO:006164030.011
positive regulation of response to stimulusGO:0048584800.011
embryonic organ morphogenesisGO:00485622740.011
phosphorus metabolic processGO:00067931090.011
cellular response to prostaglandin stimulusGO:007137930.011
positive regulation of gtpase activityGO:004354710.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.011
regulation of cytokine productionGO:000181730.011
olfactory lobe developmentGO:002198840.011
ovulation cycle processGO:002260220.011
peripheral nervous system neuron differentiationGO:0048934280.011
positive regulation of multi organism processGO:004390230.011
cellular cation homeostasisGO:0030003170.011
positive regulation of myeloid cell differentiationGO:004563920.011
regulation of erk1 and erk2 cascadeGO:007037240.011
post embryonic morphogenesisGO:000988640.011
regulation of gtp catabolic processGO:003312420.011
nuclear transportGO:005116940.011
ovarian follicle developmentGO:000154120.011
locomotor rhythmGO:004547530.011
multicellular organismal signalingGO:0035637220.010
negative regulation of rna biosynthetic processGO:1902679450.010
heart morphogenesisGO:00030071560.010
response to vitaminGO:003327330.010
positive regulation of leukocyte mediated immunityGO:000270510.010
lymphocyte proliferationGO:004665110.010
endocrine processGO:005088620.010
cation transmembrane transportGO:0098655650.010
Zebrafish
water homeostasisGO:003010440.010
ovulation cycleGO:004269820.010
antimicrobial humoral responseGO:001973020.010
nucleocytoplasmic transportGO:000691340.010
ear developmentGO:00435831270.010
regulation of circadian rhythmGO:004275240.010
actin filament based processGO:0030029640.010
defense response to fungusGO:005083220.010
pigment granule localizationGO:0051875250.010
bile acid and bile salt transportGO:001572110.010
Rat
negative regulation of epithelial cell proliferationGO:005068010.010
growthGO:00400071740.010
positive regulation of nucleobase containing compound metabolic processGO:0045935690.010
regulation of intracellular protein transportGO:003315730.010
regulation of response to stressGO:0080134360.010
neuromuscular process controlling balanceGO:005088530.010
response to glucocorticoidGO:005138410.010
erythrocyte homeostasisGO:0034101550.010

mipa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.063
immune system diseaseDOID:291400.023
musculoskeletal system diseaseDOID:1700.022
connective tissue diseaseDOID:6500.015
bone diseaseDOID:008000100.015
anemiaDOID:235500.014
aplastic anemiaDOID:1244900.014
hematopoietic system diseaseDOID:7400.014
bone marrow diseaseDOID:496100.014
cardiovascular system diseaseDOID:128700.012
disease of metabolismDOID:001466700.012
intrinsic cardiomyopathyDOID:006003600.011
muscular diseaseDOID:008000000.011
heart diseaseDOID:11400.011
muscle tissue diseaseDOID:6600.011
myopathyDOID:42300.011
cardiomyopathyDOID:005070000.011
nervous system diseaseDOID:86300.010