Danio rerio

0 known processes

ireb2

iron-responsive element binding protein 2

(Aliases: im:7153062)

ireb2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
digestive system processGO:002260090.539
Mouse
intestinal absorptionGO:005089220.378
Mouse
cellular transition metal ion homeostasisGO:004691630.349
Mouse
cellular macromolecule metabolic processGO:00442603910.224
Mouse
regulation of biosynthetic processGO:00098892500.208
Mouse
regulation of metabolic processGO:00192223590.201
Mouse
organic substance biosynthetic processGO:19015762890.198
Mouse
single organism transportGO:00447652060.197
Mouse
macromolecule biosynthetic processGO:00090592270.180
Mouse
single organism localizationGO:19025782250.178
Mouse
transition metal ion homeostasisGO:005507650.167
Mouse
gene expressionGO:00104672520.150
Mouse
metal ion homeostasisGO:0055065260.141
Mouse
regulation of cellular biosynthetic processGO:00313262450.141
Mouse
regulation of cellular metabolic processGO:00313233200.139
Mouse
cellular biosynthetic processGO:00442492860.137
Mouse
cation homeostasisGO:0055080330.127
Mouse
hematopoietic or lymphoid organ developmentGO:00485341910.115
Mouse
larval developmentGO:000216420.105
cellular iron ion homeostasisGO:000687930.099
Mouse
regulation of macromolecule metabolic processGO:00602553170.098
Mouse
establishment of localizationGO:00512342440.096
Mouse
hemopoiesisGO:00300971830.092
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.085
Mouse
protein metabolic processGO:00195381830.079
Mouse
regulation of biological qualityGO:00650082630.071
Mouse
cellular cation homeostasisGO:0030003170.070
Mouse
chemical homeostasisGO:0048878490.070
Mouse
cellular protein metabolic processGO:00442671290.067
Mouse
phagocytosisGO:000690930.066
sequestering of metal ionGO:005123830.064
endosomal transportGO:001619720.064
regulation of protein targetingGO:190353320.060
regulation of gene expressionGO:00104682650.058
Mouse
cellular macromolecule biosynthetic processGO:00346452240.058
Mouse
nucleic acid templated transcriptionGO:00976591810.057
translationGO:000641250.053
Mouse
establishment of protein localization to organelleGO:007259440.051
cellular aromatic compound metabolic processGO:00067252950.049
Mouse
regulation of cell activationGO:005086510.048
regulation of translationGO:000641730.046
Mouse
rna metabolic processGO:00160702190.045
regulation of response to stimulusGO:00485832690.044
digestionGO:0007586110.043
Mouse
positive regulation of transportGO:005105020.043
cellular response to extracellular stimulusGO:003166820.042
leukocyte proliferationGO:007066110.042
i kappab kinase nf kappab signalingGO:000724940.041
homeostatic processGO:00425921420.041
Mouse
maintenance of locationGO:005123540.041
multicellular organism growthGO:003526440.040
cellular amide metabolic processGO:004360340.040
cellular response to starvationGO:000926710.039
cellular response to external stimulusGO:007149620.039
positive regulation of i kappab kinase nf kappab signalingGO:004312330.039
autophagyGO:000691440.038
regulation of nucleic acid templated transcriptionGO:19035062130.037
extrinsic apoptotic signaling pathwayGO:009719130.035
posttranscriptional regulation of gene expressionGO:0010608140.034
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.034
nuclear importGO:005117030.034
nucleobase containing compound metabolic processGO:00061392740.034
transportGO:00068102200.033
Mouse
protein import into nucleusGO:000660630.032
cellular nitrogen compound metabolic processGO:00346412900.032
Mouse
mitochondrion organizationGO:000700540.031
cellular response to molecule of bacterial originGO:007121930.031
nucleocytoplasmic transportGO:000691340.031
protein localization to nucleusGO:003450430.031
sequestering of calcium ionGO:005120830.031
nitrogen compound metabolic processGO:00068073190.031
Mouse
wnt signaling pathwayGO:0016055800.030
regulation of multicellular organism growthGO:004001440.030
signal transductionGO:00071654550.030
nuclear transportGO:005116940.030
transcription dna templatedGO:00063511810.030
regulation of nitrogen compound metabolic processGO:00511712510.030
cellular nitrogen compound biosynthetic processGO:00442712180.030
Mouse
agingGO:000756820.029
response to stressGO:00069502630.029
organonitrogen compound metabolic processGO:1901564740.029
Mouse
vasculature developmentGO:00019442780.029
positive regulation of wound healingGO:009030310.029
regulation of protein complex assemblyGO:004325430.028
modification dependent macromolecule catabolic processGO:004363230.028
single organism nuclear importGO:190259330.028
protein targeting to nucleusGO:004474430.028
response to external stimulusGO:00096052640.027
organic cyclic compound metabolic processGO:19013603010.026
Mouse
regulation of protein transportGO:005122330.026
cell surface receptor signaling pathwayGO:00071663250.026
heterocycle biosynthetic processGO:00181302150.026
Mouse
positive regulation of cellular processGO:00485222010.026
aromatic compound biosynthetic processGO:00194382170.026
Mouse
nucleic acid metabolic processGO:00903042440.026
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.026
internal peptidyl lysine acetylationGO:001839320.026
single organism metabolic processGO:00447102170.025
Mouse
ion homeostasisGO:0050801410.025
Mouse
mononuclear cell proliferationGO:003294310.025
regulation of protein import into nucleusGO:004230620.025
cellular response to biotic stimulusGO:007121630.025
lipid storageGO:001991510.025
protein acetylationGO:000647320.025
translational initiationGO:000641330.025
positive regulation of cellular component biogenesisGO:004408930.024
nucleobase containing compound biosynthetic processGO:00346542050.024
regulation of bindingGO:005109830.024
protein importGO:001703830.024
single organism biosynthetic processGO:0044711710.024
Mouse
heterocycle metabolic processGO:00464832900.024
Mouse
convergent extensionGO:00600261180.023
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.023
regulation of cellular amine metabolic processGO:003323800.023
regulation of cytoplasmic transportGO:190364940.023
positive regulation of biological processGO:00485182530.023
protein acylationGO:004354330.023
proteasomal protein catabolic processGO:001049820.023
regulation of transcription dna templatedGO:00063552130.023
stem cell maintenanceGO:001982740.023
proteolysis involved in cellular protein catabolic processGO:005160330.022
growthGO:00400071740.022
peptidyl lysine acetylationGO:001839420.022
membrane fusionGO:006102520.022
negative regulation of protein phosphorylationGO:000193340.022
amine metabolic processGO:000930820.022
negative regulation of biosynthetic processGO:0009890550.022
response to nutrientGO:000758430.022
osteoclast differentiationGO:003031610.022
Mouse
cellular homeostasisGO:0019725260.022
Mouse
response to external biotic stimulusGO:0043207970.022
regulation of intracellular protein transportGO:003315730.021
cellular response to nutrient levelsGO:003166920.021
protein polyubiquitinationGO:000020940.021
regulation of cell communicationGO:00106462320.021
regulation of cellular protein metabolic processGO:0032268520.021
Mouse
regulation of establishment of protein localizationGO:007020140.021
cellular amine metabolic processGO:004410620.021
single organism membrane fusionGO:004480120.021
regulation of production of molecular mediator of immune responseGO:000270010.021
regulation of protein localization to nucleusGO:190018020.020
regulation of meiotic cell cycleGO:005144510.020
embryonic organ developmentGO:00485683810.020
internal protein amino acid acetylationGO:000647520.020
positive regulation of cell cycleGO:004578730.020
toll like receptor signaling pathwayGO:000222440.020
negative regulation of nitrogen compound metabolic processGO:0051172590.020
positive regulation of catabolic processGO:000989640.020
organelle fusionGO:004828430.020
organic cyclic compound biosynthetic processGO:19013622230.020
Mouse
sleepGO:003043110.020
morphogenesis of an epitheliumGO:00020093330.019
regulation of cellular ketone metabolic processGO:001056570.019
meiotic nuclear divisionGO:000712640.019
modification dependent protein catabolic processGO:001994130.019
protein heterooligomerizationGO:005129110.019
cellular component assemblyGO:00226071700.019
cytosolic calcium ion transportGO:006040130.019
response to other organismGO:0051707970.019
multicellular organismal metabolic processGO:004423620.019
signal transduction in absence of ligandGO:003803410.019
regulation of cytokine productionGO:000181730.018
positive regulation of immune effector processGO:000269930.018
positive regulation of cellular catabolic processGO:003133130.018
response to carbohydrateGO:000974330.018
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.018
regulation of rna metabolic processGO:00512522240.018
regulation of rna biosynthetic processGO:20011412130.018
response to abiotic stimulusGO:00096281220.018
regulation of metal ion transportGO:001095940.018
regulation of cellular amino acid metabolic processGO:000652100.018
mitotic dna integrity checkpointGO:004477440.018
ubiquitin dependent protein catabolic processGO:000651130.018
lymphocyte proliferationGO:004665110.018
positive regulation of map kinase activityGO:004340630.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
cellular ketone metabolic processGO:0042180110.017
regulation of reactive oxygen species metabolic processGO:200037720.017
response to monosaccharideGO:003428430.017
positive regulation of protein complex assemblyGO:003133420.017
response to hexoseGO:000974630.017
regulation of developmental processGO:00507932470.017
cellular component movementGO:00069283350.017
cellular response to lipopolysaccharideGO:007122230.017
cellular metal ion homeostasisGO:0006875160.017
Mouse
regulation of wound healingGO:006104120.017
rna biosynthetic processGO:00327741810.017
positive regulation of erk1 and erk2 cascadeGO:007037420.017
positive regulation of myeloid cell differentiationGO:004563920.017
digestive tract morphogenesisGO:00485462310.017
peptide metabolic processGO:000651810.017
regulation of protein metabolic processGO:0051246560.017
Mouse
cellular component biogenesisGO:00440851780.016
cell substrate adhesionGO:003158940.016
rna localizationGO:000640340.016
regulation of autophagyGO:001050630.016
regulation of nucleocytoplasmic transportGO:004682220.016
guanosine containing compound metabolic processGO:190106840.016
regulation of erk1 and erk2 cascadeGO:007037240.016
negative regulation of cellular catabolic processGO:003133030.016
regulation of mrna processingGO:005068430.016
antimicrobial humoral responseGO:001973020.016
protein secretionGO:000930610.016
negative regulation of response to stimulusGO:00485851040.016
carboxylic acid metabolic processGO:0019752220.016
peptide transportGO:001583310.016
mitochondrial transportGO:000683920.016
positive regulation of cytokine productionGO:000181920.015
positive regulation of apoptotic signaling pathwayGO:200123510.015
cytoskeleton dependent cytokinesisGO:006164030.015
compound eye developmentGO:004874920.015
golgi vesicle transportGO:004819330.015
biosynthetic processGO:00090582940.015
Mouse
mitotic dna damage checkpointGO:004477340.015
macroautophagyGO:001623610.015
regulation of signal transductionGO:00099662250.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
cell motilityGO:00488702440.015
regulation of circadian rhythmGO:004275240.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
tube morphogenesisGO:00352393490.015
carbon dioxide transportGO:001567030.015
regulation of alternative mrna splicing via spliceosomeGO:000038110.015
nucleic acid transportGO:005065720.015
regulation of organ growthGO:004662030.015
oxoacid metabolic processGO:0043436310.015
cofactor metabolic processGO:0051186150.015
Mouse
negative regulation of protein transportGO:005122430.015
somatic muscle developmentGO:000752540.015
cellular carbohydrate metabolic processGO:004426240.015
dorsal ventral pattern formationGO:00099531250.015
negative regulation of leukocyte differentiationGO:190210610.015
gas transportGO:001566930.015
cellular amino acid metabolic processGO:000652070.014
locomotor rhythmGO:004547530.014
regulation of macromolecule biosynthetic processGO:00105562250.014
Mouse
negative regulation of kinase activityGO:003367340.014
regulation of signalingGO:00230512350.014
response to chemicalGO:00422213200.014
cellular component disassemblyGO:002241110.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
exocytosisGO:000688710.014
positive regulation of canonical wnt signaling pathwayGO:009026340.014
cellular ion homeostasisGO:0006873170.014
Mouse
negative regulation of cellular processGO:00485232830.014
tube closureGO:006060610.014
positive regulation of lymphocyte mediated immunityGO:000270810.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
regulation of organelle assemblyGO:190211540.014
response to biotic stimulusGO:0009607970.014
primary neural tube formationGO:001402010.014
stem cell proliferationGO:007208940.014
regulation of mrna splicing via spliceosomeGO:004802430.014
organelle organizationGO:00069962270.013
positive regulation of dna metabolic processGO:005105410.013
immune system processGO:00023762410.013
Mouse
negative regulation of gene expressionGO:0010629650.013
regulation of dendrite developmentGO:005077330.013
regulation of blood coagulationGO:003019310.013
regulation of carbohydrate metabolic processGO:000610940.013
blood vessel developmentGO:00015682460.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
digestive tract developmentGO:00485652650.013
positive regulation of cellular amine metabolic processGO:003324000.013
neurotransmitter transportGO:000683620.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
organic acid metabolic processGO:0006082310.013
regulation of protein ubiquitinationGO:003139630.013
transcription from rna polymerase ii promoterGO:0006366800.013
gtp catabolic processGO:000618420.013
protein modification processGO:00362111000.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
negative regulation of macromolecule metabolic processGO:0010605760.013
regulation of multicellular organismal processGO:00512392770.013
neuron neuron synaptic transmissionGO:000727010.013
bone remodelingGO:004684920.013
positive regulation of cytoskeleton organizationGO:005149530.013
calcium ion transport into cytosolGO:006040230.013
response to glucoseGO:000974930.013
erk1 and erk2 cascadeGO:007037140.013
negative regulation of mapk cascadeGO:004340940.013
positive regulation of response to stimulusGO:0048584800.013
somatic stem cell maintenanceGO:003501910.013
g2 m transition of mitotic cell cycleGO:000008640.013
cellular component morphogenesisGO:00329893360.012
positive regulation of cell activationGO:005086710.012
response to drugGO:004249330.012
regulation of sequestering of calcium ionGO:005128240.012
cell morphogenesis involved in differentiationGO:00009041950.012
microtubule organizing center organizationGO:003102310.012
regulation of cell deathGO:00109411030.012
release of sequestered calcium ion into cytosolGO:005120930.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
regulation of reproductive processGO:200024140.012
regulation of synapse assemblyGO:005196330.012
cytokinesisGO:000091030.012
negative regulation of metabolic processGO:0009892860.012
regulation of nucleoside metabolic processGO:000911820.012
positive regulation of multi organism processGO:004390230.012
positive regulation of interferon beta productionGO:003272810.012
apoptotic processGO:00069151160.012
regulation of purine nucleotide catabolic processGO:003312120.012
organic acid catabolic processGO:001605430.012
myeloid cell differentiationGO:0030099860.012
Mouse
endosome organizationGO:000703220.012
cellular protein catabolic processGO:004425740.012
chordate embryonic developmentGO:00430092710.012
regulation of dna replicationGO:000627530.012
cellular localizationGO:0051641970.012
histone h3 k4 methylationGO:005156820.012
cellular protein modification processGO:00064641000.012
regulation of rho protein signal transductionGO:003502320.012
adult behaviorGO:003053420.011
embryo development ending in birth or egg hatchingGO:00097922710.011
synaptic growth at neuromuscular junctionGO:005112420.011
negative regulation of mitosisGO:004583930.011
regulation of cell shapeGO:000836010.011
establishment of rna localizationGO:005123630.011
interspecies interaction between organismsGO:004441940.011
apoptotic process involved in developmentGO:190274220.011
centrosome cycleGO:000709810.011
regulation of stem cell differentiationGO:200073640.011
g1 s transition of mitotic cell cycleGO:000008210.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
hormone secretionGO:004687920.011
negative regulation of catabolic processGO:000989530.011
positive regulation of nucleotide catabolic processGO:003081310.011
negative regulation of sequestering of calcium ionGO:005128340.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
tissue remodelingGO:004877140.011
protein dephosphorylationGO:000647030.011
positive regulation of gtpase activityGO:004354710.011
centrosome duplicationGO:005129810.011
positive regulation of secretionGO:005104710.011
regulation of cellular protein catabolic processGO:190336210.011
regulation of protein complex disassemblyGO:004324410.011
regulation of growth rateGO:004000910.011
negative regulation of cellular metabolic processGO:0031324770.011
centrosome organizationGO:005129710.011
protein targeting to membraneGO:000661210.011
b cell activationGO:004211320.011
cellular response to oxygen levelsGO:007145310.011
mitotic cytokinesisGO:000028130.011
positive regulation of cell killingGO:003134320.011
adherens junction organizationGO:003433240.011
regulation of neurotransmitter transportGO:005158810.011
protein localization to plasma membraneGO:007265910.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.010
negative regulation of biological processGO:00485193040.010
brain developmentGO:00074202930.010
production of molecular mediator of immune responseGO:000244020.010
sensory system developmentGO:0048880760.010
organism emergence from protective structureGO:007168440.010
response to organic substanceGO:00100331530.010
regulation of bone remodelingGO:004685020.010
peptidyl serine modificationGO:001820920.010
cell migrationGO:00164772370.010
gtp metabolic processGO:004603940.010
negative regulation of multi organism processGO:004390130.010
single fertilizationGO:000733830.010
regionalizationGO:00030022740.010
neuron differentiationGO:00301823530.010
lipid catabolic processGO:001604240.010
carbohydrate biosynthetic processGO:001605110.010
alcohol biosynthetic processGO:004616520.010
neurotransmitter secretionGO:000726920.010
regulation of calcium ion transportGO:005192420.010
regulation of synapse organizationGO:005080730.010
regulation of nucleotide catabolic processGO:003081120.010

ireb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.020
disease of cellular proliferationDOID:1456600.019
organ system cancerDOID:005068600.019
cancerDOID:16200.019
inherited metabolic disorderDOID:65500.018
nervous system diseaseDOID:86300.015
disease of anatomical entityDOID:700.015
eye diseaseDOID:561400.012
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012