Danio rerio

38 known processes

irf8

interferon regulatory factor 8

(Aliases: zgc:92252)

irf8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of inflammatory responseGO:005072910.224
central nervous system developmentGO:00074173870.177
agingGO:000756820.149
response to stressGO:00069502630.137
response to external stimulusGO:00096052640.137
regulation of cellular extravasationGO:000269110.110
multicellular organismal metabolic processGO:004423620.103
larval developmentGO:000216420.103
sleepGO:003043110.082
homeostatic processGO:00425921420.079
locomotionGO:00400113130.079
regulation of inflammatory responseGO:005072720.077
regulation of erythrocyte differentiationGO:004564620.073
regulation of multicellular organismal processGO:00512392770.072
immune system processGO:00023762410.071
female sex differentiationGO:004666040.068
transmembrane transportGO:00550851200.067
homeostasis of number of cellsGO:0048872620.066
regulation of cell activationGO:005086510.063
regulation of apoptotic processGO:0042981980.061
signal transductionGO:00071654550.061
hematopoietic or lymphoid organ developmentGO:00485341910.059
negative regulation of leukocyte differentiationGO:190210610.058
tube morphogenesisGO:00352393490.056
regulation of protein catabolic processGO:004217610.055
regulation of biological qualityGO:00650082630.054
female gonad developmentGO:000858540.054
hemopoiesisGO:00300971830.054
immune system developmentGO:00025201910.053
fin developmentGO:0033333770.053
response to alkaloidGO:004327920.052
development of primary female sexual characteristicsGO:004654540.051
regulation of multicellular organism growthGO:004001440.050
taxisGO:00423301090.050
regulation of developmental processGO:00507932470.049
negative regulation of biological processGO:00485193040.048
head developmentGO:00603223030.047
g protein coupled receptor signaling pathwayGO:0007186740.047
regulation of bone remodelingGO:004685020.047
vasculature developmentGO:00019442780.046
multicellular organism growthGO:003526440.045
regulation of circadian sleep wake cycleGO:004274910.045
negative regulation of cellular processGO:00485232830.045
negative regulation of myeloid cell differentiationGO:004563810.045
phagocytosisGO:000690930.044
regulation of cell differentiationGO:00455951420.043
regulation of mrna splicing via spliceosomeGO:004802430.042
erythrocyte homeostasisGO:0034101550.042
proteolysis involved in cellular protein catabolic processGO:005160330.042
myeloid leukocyte differentiationGO:0002573150.041
response to chemicalGO:00422213200.041
regulation of mrna processingGO:005068430.041
regulation of chronic inflammatory responseGO:000267610.040
positive regulation of catabolic processGO:000989640.039
cellular amide metabolic processGO:004360340.039
cell surface receptor signaling pathwayGO:00071663250.039
positive regulation of map kinase activityGO:004340630.038
embryonic heart tube developmentGO:00350501330.038
cell agingGO:000756920.038
embryonic organ developmentGO:00485683810.038
stem cell maintenanceGO:001982740.038
circadian sleep wake cycleGO:004274520.037
sensory organ developmentGO:00074233930.036
regulation of metabolic processGO:00192223590.036
eye developmentGO:00016542770.035
cell migrationGO:00164772370.035
cellular response to external stimulusGO:007149620.034
epithelial tube morphogenesisGO:00605621480.034
nuclear transportGO:005116940.034
positive regulation of cell activationGO:005086710.033
negative regulation of myeloid leukocyte differentiationGO:000276210.033
response to nutrientGO:000758430.032
nuclear exportGO:005116810.032
regulation of primary metabolic processGO:00800903110.032
regulation of programmed cell deathGO:00430671010.031
nucleocytoplasmic transportGO:000691340.031
digestive tract morphogenesisGO:00485462310.031
neuron developmentGO:00486662620.031
regulation of metal ion transportGO:001095940.030
centrosome organizationGO:005129710.030
response to amineGO:001407510.030
regulation of tube sizeGO:003515020.030
cellular response to chemical stimulusGO:00708871570.030
regulation of cellular component movementGO:0051270550.029
programmed cell deathGO:00125011190.029
tissue remodelingGO:004877140.029
leukocyte differentiationGO:0002521250.028
positive regulation of cytokine productionGO:000181920.028
regulation of response to stimulusGO:00485832690.028
cell morphogenesisGO:00009022890.028
positive regulation of cellular catabolic processGO:003133130.028
regulation of myeloid leukocyte differentiationGO:000276150.028
nucleic acid templated transcriptionGO:00976591810.027
regulation of establishment of protein localizationGO:007020140.027
brain developmentGO:00074202930.027
cellular protein catabolic processGO:004425740.027
amine metabolic processGO:000930820.027
gene expressionGO:00104672520.027
cellular response to nutrient levelsGO:003166920.027
negative regulation of gene expressionGO:0010629650.027
transportGO:00068102200.026
chemotaxisGO:00069351040.026
response to organic substanceGO:00100331530.026
cellular component movementGO:00069283350.026
neuron differentiationGO:00301823530.025
cellular response to starvationGO:000926710.025
homeostasis of number of cells within a tissueGO:004887340.025
cell motilityGO:00488702440.025
proteolysisGO:0006508380.025
regulation of blood vessel sizeGO:005088020.025
negative regulation of protein phosphorylationGO:000193340.025
membrane hyperpolarizationGO:006008110.025
myeloid leukocyte migrationGO:0097529120.025
negative regulation of protein kinase activityGO:000646940.024
digestive system developmentGO:00551232890.024
organic acid metabolic processGO:0006082310.024
response to endogenous stimulusGO:0009719830.024
eye morphogenesisGO:00485921440.024
mitochondrion organizationGO:000700540.024
retina development in camera type eyeGO:00600411460.024
regulation of cell shapeGO:000836010.024
smooth muscle contractionGO:000693920.023
lateral line system developmentGO:0048925760.023
monocyte differentiationGO:003022420.023
regulation of transcription dna templatedGO:00063552130.023
generation of neuronsGO:00486993850.023
regulation of cell developmentGO:00602841000.023
myeloid cell developmentGO:0061515320.022
myeloid cell differentiationGO:0030099860.022
internal peptidyl lysine acetylationGO:001839320.022
blood vessel developmentGO:00015682460.022
cellular component morphogenesisGO:00329893360.022
cellular macromolecule metabolic processGO:00442603910.022
positive regulation of translationGO:004572710.022
protein acetylationGO:000647320.022
regulation of macromolecule metabolic processGO:00602553170.022
antimicrobial humoral responseGO:001973020.022
regulation of cell deathGO:00109411030.022
circadian sleep wake cycle sleepGO:005080210.021
heart developmentGO:00075073130.021
neuron neuron synaptic transmissionGO:000727010.021
regulation of cellular biosynthetic processGO:00313262450.021
regulation of rna metabolic processGO:00512522240.021
protein targeting to nucleusGO:004474430.021
bone remodelingGO:004684920.021
regulation of cytokine productionGO:000181730.021
hepaticobiliary system developmentGO:0061008980.021
collagen metabolic processGO:003296320.021
nucleobase containing compound biosynthetic processGO:00346542050.021
cell projection organizationGO:00300302840.021
regulation of cell motilityGO:2000145460.020
regulation of transmembrane transporter activityGO:002289820.020
one carbon compound transportGO:0019755140.020
angiogenesisGO:00015251580.020
internal protein amino acid acetylationGO:000647520.020
stem cell developmentGO:0048864820.020
compound eye developmentGO:004874920.020
neuron projection developmentGO:00311751800.020
nitrogen compound metabolic processGO:00068073190.020
regulation of biosynthetic processGO:00098892500.020
camera type eye developmentGO:00430102220.020
response to oxygen containing compoundGO:1901700550.020
single organism transportGO:00447652060.020
sensory system developmentGO:0048880760.020
positive regulation of cellular component biogenesisGO:004408930.020
regulation of circadian rhythmGO:004275240.020
macrophage differentiationGO:003022570.019
regulation of protein transportGO:005122330.019
response to drugGO:004249330.019
negative regulation of defense responseGO:003134820.019
cell cycle g2 m phase transitionGO:004483940.019
sprouting angiogenesisGO:0002040530.019
microtubule organizing center organizationGO:003102310.019
regulation of rna biosynthetic processGO:20011412130.019
regulation of synapse assemblyGO:005196330.019
regulation of circadian sleep wake cycle sleepGO:004518710.019
establishment of localizationGO:00512342440.019
cellular response to extracellular stimulusGO:003166820.019
adherens junction organizationGO:003433240.018
single organism localizationGO:19025782250.018
regulation of leukocyte migrationGO:000268580.018
response to lipidGO:0033993600.018
guanosine containing compound metabolic processGO:190106840.018
nucleic acid metabolic processGO:00903042440.018
regulation of gene expressionGO:00104682650.018
maintenance of locationGO:005123540.018
rna localizationGO:000640340.018
cellular nitrogen compound biosynthetic processGO:00442712180.018
positive regulation of response to external stimulusGO:003210390.018
leukocyte chemotaxisGO:0030595120.018
protein acylationGO:004354330.018
cell deathGO:00082191210.018
phosphatidylinositol mediated signalingGO:004801520.018
regulation of erk1 and erk2 cascadeGO:007037240.018
response to inorganic substanceGO:0010035380.017
protein secretionGO:000930610.017
regulation of transporter activityGO:003240920.017
regulation of bindingGO:005109830.017
hindbrain developmentGO:0030902910.017
sensory organ morphogenesisGO:00905962000.017
ion transportGO:00068111140.017
establishment of protein localization to organelleGO:007259440.017
protein import into nucleusGO:000660630.017
regulation of cell communicationGO:00106462320.017
regulation of signal transductionGO:00099662250.017
response to woundingGO:00096111160.017
positive regulation of cell adhesionGO:004578510.017
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.017
regulation of multicellular organismal developmentGO:20000262230.017
regulation of ion transmembrane transporter activityGO:003241220.017
response to glucocorticoidGO:005138410.017
deathGO:00162651210.017
b cell activationGO:004211320.017
cellular extravasationGO:004512310.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
response to foodGO:003209410.017
pectoral fin developmentGO:0033339500.016
regulation of locomotionGO:0040012550.016
embryonic skeletal system morphogenesisGO:0048704930.016
circadian sleep wake cycle processGO:002241020.016
response to vitaminGO:003327330.016
monoamine transportGO:001584410.016
phagocytosis engulfmentGO:000691110.016
regulation of postsynaptic membrane potentialGO:006007810.016
cellular response to organic substanceGO:00713101050.016
organelle organizationGO:00069962270.016
regulation of cellular amino acid metabolic processGO:000652100.016
myeloid cell homeostasisGO:0002262560.016
regulation of blood pressureGO:000821710.016
lymph vessel morphogenesisGO:0036303250.016
regulation of synaptic plasticityGO:004816710.016
liver developmentGO:0001889960.016
activation of mapk activityGO:000018730.016
response to amphetamineGO:000197510.016
cellular modified amino acid metabolic processGO:000657530.016
heterocycle biosynthetic processGO:00181302150.016
cell matrix adhesionGO:000716040.016
peptidyl lysine acetylationGO:001839420.016
neutrophil differentiationGO:003022360.016
positive regulation of secretionGO:005104710.016
cell morphogenesis involved in differentiationGO:00009041950.016
regulation of signalingGO:00230512350.016
regulation of cell migrationGO:0030334400.016
positive regulation of transportGO:005105020.015
regulation of organelle assemblyGO:190211540.015
cellular macromolecule biosynthetic processGO:00346452240.015
astrocyte differentiationGO:004870810.015
response to external biotic stimulusGO:0043207970.015
blood vessel morphogenesisGO:00485142160.015
positive regulation of secretion by cellGO:190353210.015
negative regulation of kinase activityGO:003367340.015
cellular component disassemblyGO:002241110.015
regulation of tissue remodelingGO:003410320.015
response to amino acidGO:004320020.015
nucleic acid transportGO:005065720.015
protein importGO:001703830.015
gtp catabolic processGO:000618420.015
gliogenesisGO:0042063450.015
negative regulation of mapk cascadeGO:004340940.015
cognitionGO:005089010.015
retina morphogenesis in camera type eyeGO:0060042790.015
cellular response to oxygen levelsGO:007145310.015
somatic stem cell maintenanceGO:003501910.015
regulation of myeloid cell differentiationGO:004563780.015
erythrocyte differentiationGO:0030218540.015
adult behaviorGO:003053420.015
gland developmentGO:00487321430.015
cellular response to molecule of bacterial originGO:007121930.014
regulation of neurotransmitter transportGO:005158810.014
positive regulation of response to stimulusGO:0048584800.014
multicellular organismal homeostasisGO:0048871290.014
calcium ion transport into cytosolGO:006040230.014
regulation of cellular amine metabolic processGO:003323800.014
apoptotic processGO:00069151160.014
positive regulation of nucleotide catabolic processGO:003081310.014
cellular amine metabolic processGO:004410620.014
endocrine system developmentGO:0035270650.014
response to monosaccharideGO:003428430.014
regulation of hormone secretionGO:004688320.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
modification dependent protein catabolic processGO:001994130.014
gtp metabolic processGO:004603940.014
leukocyte proliferationGO:007066110.014
multicellular organismal macromolecule metabolic processGO:004425920.014
regulation of cellular metabolic processGO:00313233200.014
transcription dna templatedGO:00063511810.014
definitive hemopoiesisGO:0060216180.013
positive regulation of cellular processGO:00485222010.013
positive regulation of cell cycleGO:004578730.013
retinal ganglion cell axon guidanceGO:0031290350.013
positive regulation of biosynthetic processGO:0009891680.013
regulation of muscle contractionGO:000693730.013
regulation of nitrogen compound metabolic processGO:00511712510.013
proteasomal protein catabolic processGO:001049820.013
regulation of rho protein signal transductionGO:003502320.013
morphogenesis of an epitheliumGO:00020093330.013
organonitrogen compound metabolic processGO:1901564740.013
positive regulation of leukocyte differentiationGO:190210710.013
regulation of stem cell differentiationGO:200073640.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
regulation of autophagyGO:001050630.013
regulation of neurogenesisGO:0050767870.013
regulation of reproductive processGO:200024140.013
growthGO:00400071740.013
cellular response to endogenous stimulusGO:0071495680.013
regulation of cell matrix adhesionGO:000195210.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
intracellular signal transductionGO:0035556850.013
single organism metabolic processGO:00447102170.013
cell chemotaxisGO:0060326170.013
nerve developmentGO:0021675450.013
lymphocyte proliferationGO:004665110.013
regulation of nucleotide biosynthetic processGO:0030808150.013
t cell differentiation in thymusGO:003307760.013
regulation of cellular ketone metabolic processGO:001056570.013
cellular component biogenesisGO:00440851780.013
establishment of protein localization to plasma membraneGO:009000210.013
ovulation cycle processGO:002260220.013
amino acid transportGO:000686520.013
protein metabolic processGO:00195381830.012
cell projection morphogenesisGO:00488582440.012
oxoacid metabolic processGO:0043436310.012
negative regulation of cell differentiationGO:0045596460.012
localization of cellGO:00516742440.012
locomotor rhythmGO:004547530.012
positive regulation of leukocyte migrationGO:000268720.012
cell part morphogenesisGO:00329902460.012
cellular aromatic compound metabolic processGO:00067252950.012
developmental growthGO:00485891660.012
regulation of dna metabolic processGO:0051052110.012
extrinsic apoptotic signaling pathwayGO:009719130.012
regulation of protein ubiquitinationGO:003139630.012
rna metabolic processGO:00160702190.012
regulation of calcium ion transportGO:005192420.012
ribosomal small subunit biogenesisGO:004227420.012
regulation of type b pancreatic cell proliferationGO:006146910.012
cellular amino acid metabolic processGO:000652070.012
response to hexoseGO:000974630.012
multi organism processGO:00517041340.012
rna export from nucleusGO:000640510.012
b cell differentiationGO:003018310.012
positive regulation of macromolecule metabolic processGO:0010604930.012
macromolecule modificationGO:00434121110.012
regulation of meiotic cell cycleGO:005144510.012
cell substrate adhesionGO:003158940.012
single organism organelle organizationGO:19025891990.012
primitive hemopoiesisGO:0060215270.012
dna catabolic processGO:000630810.012
positive regulation of cytoskeleton organizationGO:005149530.012
lymph vessel developmentGO:0001945270.012
response to carbohydrateGO:000974330.012
positive regulation of jak stat cascadeGO:004642720.012
ovulation cycleGO:004269820.012
guanosine containing compound catabolic processGO:190106920.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
erk1 and erk2 cascadeGO:007037140.012
regulation of localizationGO:00328791040.012
mesenchymal cell developmentGO:0014031780.012
regulation of cellular protein catabolic processGO:190336210.012
chordate embryonic developmentGO:00430092710.012
nuclear importGO:005117030.012
rna transportGO:005065820.012
regulation of response to external stimulusGO:0032101310.012
negative regulation of locomotionGO:0040013180.012
ubiquitin dependent protein catabolic processGO:000651130.011
negative regulation of secretion by cellGO:190353120.011
small molecule metabolic processGO:0044281770.011
protein polyubiquitinationGO:000020940.011
regulation of synapse organizationGO:005080730.011
developmental programmed cell deathGO:001062340.011
spermatid developmentGO:000728620.011
single organism nuclear importGO:190259330.011
central nervous system neuron differentiationGO:0021953740.011
cellular protein metabolic processGO:00442671290.011
response to alcoholGO:0097305140.011
negative regulation of apoptotic processGO:0043066550.011
translational initiationGO:000641330.011
granulocyte migrationGO:0097530110.011
cellular response to lipopolysaccharideGO:007122230.011
regulation of gene expression epigeneticGO:0040029110.011
spermatid differentiationGO:004851520.011
regulation of nucleotide catabolic processGO:003081120.011
regulation of homeostatic processGO:003284490.011
response to ketoneGO:190165410.011
regulation of protein targetingGO:190353320.011
skeletal system developmentGO:00015011810.011
negative regulation of secretionGO:005104820.011
regulation of intracellular signal transductionGO:1902531570.011
dna templated transcription elongationGO:000635430.011
regulation of neuron differentiationGO:0045664560.011
cellular response to reactive oxygen speciesGO:003461420.011
actin filament polymerizationGO:003004120.011
negative regulation of cytokine productionGO:000181810.011
cranial ganglion developmentGO:006155030.011
cation homeostasisGO:0055080330.011
inositol lipid mediated signalingGO:004801720.011
cellular response to hypoxiaGO:007145610.011
dorsal motor nucleus of vagus nerve developmentGO:002174440.011
erythrocyte developmentGO:0048821240.011
regulation of protein complex assemblyGO:004325430.011
negative regulation of metabolic processGO:0009892860.011
toll like receptor signaling pathwayGO:000222440.011
meiotic nuclear divisionGO:000712640.011
lipid catabolic processGO:001604240.011
oxidoreduction coenzyme metabolic processGO:000673310.011
type b pancreatic cell proliferationGO:004434210.011
regulation of glial cell differentiationGO:004568540.011
negative regulation of rna splicingGO:003311910.010
response to hormoneGO:0009725480.010
pancreas developmentGO:0031016840.010
negative regulation of catabolic processGO:000989530.010
activation of immune responseGO:000225390.010
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.010
cellular component assembly involved in morphogenesisGO:00109271070.010
circulatory system processGO:0003013870.010
system processGO:00030081850.010
membrane invaginationGO:001032410.010
regulation of response to stressGO:0080134360.010
mitochondrial transportGO:000683920.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
heterocycle metabolic processGO:00464832900.010
leukocyte migrationGO:0050900150.010
insulin like growth factor receptor signaling pathwayGO:004800940.010
peptide metabolic processGO:000651810.010
cartilage developmentGO:0051216960.010

irf8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
disease of cellular proliferationDOID:1456600.016
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013
nervous system diseaseDOID:86300.013
eye diseaseDOID:561400.013
cancerDOID:16200.013
organ system cancerDOID:005068600.011
disease of metabolismDOID:001466700.010