Danio rerio

70 known processes

scn12ab

sodium channel, voltage gated, type XII, alpha b

(Aliases: zscn5a)

scn12ab biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of blood circulationGO:1903522320.710
heart contractionGO:0060047710.656
heart processGO:0003015710.642
system processGO:00030081850.538
transmembrane transportGO:00550851200.484
inorganic cation transmembrane transportGO:0098662500.463
regulation of ion transportGO:0043269220.379
regulation of muscle contractionGO:000693730.372
cardiac muscle cell differentiationGO:0055007300.371
sodium ion transmembrane transportGO:0035725210.369
regulation of system processGO:0044057400.369
tube morphogenesisGO:00352393490.362
blood circulationGO:0008015870.353
muscle cell differentiationGO:00426921390.320
heart loopingGO:0001947940.313
specification of symmetryGO:00097992040.300
heart developmentGO:00075073130.291
striated muscle cell differentiationGO:00511461290.275
regulation of heart contractionGO:0008016320.262
circulatory system processGO:0003013870.261
neuron differentiationGO:00301823530.259
cellular component morphogenesisGO:00329893360.250
embryonic organ developmentGO:00485683810.244
morphogenesis of an epitheliumGO:00020093330.216
determination of left right symmetryGO:00073681790.215
regulation of response to stimulusGO:00485832690.201
inorganic ion transmembrane transportGO:0098660570.193
muscle tissue developmentGO:00605371100.190
ion transmembrane transportGO:0034220910.189
heart morphogenesisGO:00030071560.183
determination of bilateral symmetryGO:00098552040.166
cardiac muscle tissue developmentGO:0048738480.163
embryonic organ morphogenesisGO:00485622740.153
epithelial tube morphogenesisGO:00605621480.141
cell projection organizationGO:00300302840.131
cell surface receptor signaling pathwayGO:00071663250.131
muscle cell developmentGO:00550011150.130
embryonic heart tube morphogenesisGO:00031431080.129
single organism transportGO:00447652060.123
organelle assemblyGO:00709251100.120
muscle structure developmentGO:00610611960.115
multicellular organismal signalingGO:0035637220.115
regulation of multicellular organismal processGO:00512392770.108
sodium ion transportGO:0006814240.104
cardiac conductionGO:006133730.103
embryonic heart tube developmentGO:00350501330.096
neuron developmentGO:00486662620.096
positive regulation of transportGO:005105020.094
cardiac myofibril assemblyGO:005500390.094
organonitrogen compound metabolic processGO:1901564740.092
striated muscle contractionGO:0006941120.091
signal transductionGO:00071654550.088
muscle system processGO:0003012200.087
transportGO:00068102200.087
regulation of stem cell proliferationGO:007209120.086
cell projection morphogenesisGO:00488582440.086
metal ion transportGO:0030001580.083
cellular aromatic compound metabolic processGO:00067252950.082
cell morphogenesis involved in neuron differentiationGO:00486671630.080
regulation of cellular macromolecule biosynthetic processGO:20001122220.080
striated muscle cell developmentGO:00550021080.079
cell part morphogenesisGO:00329902460.075
establishment of localizationGO:00512342440.075
rna biosynthetic processGO:00327741810.074
heterocycle metabolic processGO:00464832900.070
atrial cardiac myofibril assemblyGO:005500420.070
ion transportGO:00068111140.068
positive regulation of biological processGO:00485182530.067
actin filament based movementGO:003004810.067
cellular nitrogen compound metabolic processGO:00346412900.066
adult behaviorGO:003053420.065
striated muscle tissue developmentGO:00147061100.065
nucleic acid templated transcriptionGO:00976591810.065
larval developmentGO:000216420.064
cellular component assembly involved in morphogenesisGO:00109271070.063
cellular component assemblyGO:00226071700.063
regulation of multicellular organismal developmentGO:20000262230.063
cellular macromolecule metabolic processGO:00442603910.062
single organism localizationGO:19025782250.061
positive regulation of cellular processGO:00485222010.060
ventricular cardiac muscle tissue morphogenesisGO:005501020.060
regulation of apoptotic processGO:0042981980.060
regulation of actin filament based movementGO:190311510.059
cardiac muscle cell developmentGO:0055013200.059
locomotionGO:00400113130.058
ventricular cardiac muscle tissue developmentGO:000322930.058
rna metabolic processGO:00160702190.057
regulation of heart rateGO:000202750.057
response to chemicalGO:00422213200.056
cation transportGO:0006812810.055
response to external stimulusGO:00096052640.055
neuron projection morphogenesisGO:00488121610.055
regulation of nitrogen compound metabolic processGO:00511712510.054
nucleic acid metabolic processGO:00903042440.052
generation of neuronsGO:00486993850.052
apoptotic processGO:00069151160.052
single organism organelle organizationGO:19025891990.052
cell morphogenesisGO:00009022890.052
organic cyclic compound metabolic processGO:19013603010.051
myofibril assemblyGO:0030239480.051
nitrogen compound metabolic processGO:00068073190.050
regulation of ion transmembrane transportGO:0034765180.050
nucleobase containing compound metabolic processGO:00061392740.049
agingGO:000756820.047
regulation of biological qualityGO:00650082630.047
tissue remodelingGO:004877140.046
regulation of signal transductionGO:00099662250.044
cell deathGO:00082191210.042
axonogenesisGO:00074091520.042
determination of heart left right asymmetryGO:00613711170.040
ventricular cardiac myofibril assemblyGO:005500540.040
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.040
positive regulation of cell cycleGO:004578730.040
regulation of cellular metabolic processGO:00313233200.040
negative regulation of cellular processGO:00485232830.039
regulation of dendrite developmentGO:005077330.039
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.039
chemotaxisGO:00069351040.039
cardiocyte differentiationGO:0035051440.039
regulation of metal ion transportGO:001095940.039
transcription dna templatedGO:00063511810.038
amine metabolic processGO:000930820.038
regulation of membrane potentialGO:0042391230.038
regulation of metabolic processGO:00192223590.037
cardiac cell developmentGO:0055006210.037
cellular component biogenesisGO:00440851780.037
cell death in response to oxidative stressGO:003647320.037
cellular component movementGO:00069283350.036
transmission of nerve impulseGO:0019226190.036
skeletal muscle organ developmentGO:0060538780.035
neurological system processGO:0050877620.035
muscle contractionGO:0006936180.035
mechanosensory behaviorGO:000763820.035
negative regulation of biological processGO:00485193040.035
neuron projection guidanceGO:0097485860.034
cardiac conduction system developmentGO:000316110.034
actin filament based processGO:0030029640.034
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.034
nucleoside monophosphate catabolic processGO:000912540.034
action potentialGO:0001508190.033
metal ion homeostasisGO:0055065260.033
cardiac chamber formationGO:000320740.033
neuron projection developmentGO:00311751800.033
regulation of nucleic acid templated transcriptionGO:19035062130.032
organic substance biosynthetic processGO:19015762890.032
monovalent inorganic cation transportGO:0015672420.032
positive regulation of heart contractionGO:004582320.032
positive regulation of i kappab kinase nf kappab signalingGO:004312330.032
regulation of striated muscle contractionGO:000694220.032
positive regulation of cytosolic calcium ion concentrationGO:000720440.031
organelle organizationGO:00069962270.031
organic acid metabolic processGO:0006082310.031
regulation of gene expressionGO:00104682650.030
actomyosin structure organizationGO:0031032530.030
regulation of cellular response to oxidative stressGO:190040720.030
phosphorylationGO:0016310690.030
regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.029
regulation of membrane repolarizationGO:006030610.029
regulation of biosynthetic processGO:00098892500.029
carboxylic acid metabolic processGO:0019752220.029
actin mediated cell contractionGO:007025210.029
protein metabolic processGO:00195381830.029
negative regulation of kinase activityGO:003367340.029
regulation of developmental processGO:00507932470.028
regulation of macromolecule metabolic processGO:00602553170.028
regulation of tube sizeGO:003515020.028
membrane repolarizationGO:008600920.028
response to abiotic stimulusGO:00096281220.028
immune system processGO:00023762410.027
biosynthetic processGO:00090582940.027
regulation of cardiac muscle cell contractionGO:008600410.027
macromolecule biosynthetic processGO:00090592270.027
taxisGO:00423301090.027
positive regulation of catabolic processGO:000989640.027
oxoacid metabolic processGO:0043436310.027
sarcomerogenesisGO:004876940.026
single organism metabolic processGO:00447102170.026
positive regulation of nitrogen compound metabolic processGO:0051173690.026
regulation of cell communicationGO:00106462320.026
neurotransmitter transportGO:000683620.026
regulation of blood pressureGO:000821710.026
regulation of nucleoside metabolic processGO:000911820.026
regulation of jak stat cascadeGO:004642530.026
autophagyGO:000691440.025
cellular amino acid metabolic processGO:000652070.025
regulation of ion transmembrane transporter activityGO:003241220.025
regulation of transporter activityGO:003240920.025
regulation of response to oxidative stressGO:190288220.025
nucleoside phosphate metabolic processGO:0006753280.025
photoreceptor cell fate commitmentGO:004655210.025
deathGO:00162651210.024
cytokinesisGO:000091030.024
regulation of macromolecule biosynthetic processGO:00105562250.024
regulation of programmed cell deathGO:00430671010.024
regulation of rna metabolic processGO:00512522240.024
meiotic nuclear divisionGO:000712640.024
cellular response to chemical stimulusGO:00708871570.024
multi organism processGO:00517041340.023
regulation of localizationGO:00328791040.023
purine nucleoside monophosphate catabolic processGO:000912840.023
sensory organ morphogenesisGO:00905962000.023
regulation of cellular biosynthetic processGO:00313262450.023
positive regulation of cellular component biogenesisGO:004408930.023
brain developmentGO:00074202930.023
single organism behaviorGO:0044708240.022
i kappab kinase nf kappab signalingGO:000724940.022
small molecule metabolic processGO:0044281770.022
cardiac muscle contractionGO:006004860.022
positive regulation of cellular metabolic processGO:0031325940.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
glial cell proliferationGO:001400940.022
regulation of transmembrane transporter activityGO:002289820.022
regulation of blood vessel sizeGO:005088020.022
calcium ion importGO:007050940.022
regulation of protein complex assemblyGO:004325430.022
hormone secretionGO:004687920.022
smooth muscle contractionGO:000693920.022
regulation of signalingGO:00230512350.022
detection of stimulusGO:0051606290.021
cellular macromolecule biosynthetic processGO:00346452240.021
glomerulus vasculature developmentGO:007201220.021
sensory organ developmentGO:00074233930.021
negative regulation of response to stimulusGO:00485851040.021
regulation of transmembrane transportGO:0034762180.021
mesodermal cell fate specificationGO:0007501120.021
regulation of cardiac muscle contractionGO:005511720.021
regulation of calcium ion transportGO:005192420.020
fatty acid catabolic processGO:000906210.020
axon developmentGO:00615641660.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
positive regulation of neural precursor cell proliferationGO:200017910.020
cation transmembrane transportGO:0098655650.020
locomotory behaviorGO:0007626340.020
ribonucleoside monophosphate catabolic processGO:000915840.020
organic cyclic compound biosynthetic processGO:19013622230.020
positive regulation of blood circulationGO:190352420.020
actin cytoskeleton organizationGO:0030036630.020
ion homeostasisGO:0050801410.020
neurotransmitter secretionGO:000726920.019
response to alkaloidGO:004327920.019
regulation of transcription dna templatedGO:00063552130.019
response to carbohydrateGO:000974330.019
atrial cardiac muscle cell developmentGO:005501440.019
regulation of meiotic cell cycleGO:005144510.019
regulation of synaptic plasticityGO:004816710.019
protein modification processGO:00362111000.019
regulation of rna biosynthetic processGO:20011412130.019
regulation of response to stressGO:0080134360.019
stem cell fate commitmentGO:004886510.019
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.018
regulation of skeletal muscle fiber developmentGO:004874220.018
regulation of cellular amine metabolic processGO:003323800.018
retinal rod cell developmentGO:004654840.018
negative regulation of catabolic processGO:000989530.018
activation of immune responseGO:000225390.018
ventricular cardiac muscle cell differentiationGO:005501260.018
neuroblast proliferationGO:000740520.018
eye photoreceptor cell developmentGO:0042462300.017
regulation of protein transportGO:005122330.017
cardiac atrium morphogenesisGO:000320920.017
peripheral nervous system developmentGO:0007422550.017
cell morphogenesis involved in differentiationGO:00009041950.017
regulation of oxidative stress induced cell deathGO:190320120.017
negative regulation of protein phosphorylationGO:000193340.017
regulation of purine nucleotide catabolic processGO:003312120.017
retinal cone cell developmentGO:004654980.017
cell proliferation involved in heart morphogenesisGO:006132320.017
amino acid transportGO:000686520.017
protein heterooligomerizationGO:005129110.017
regulation of neurogenesisGO:0050767870.017
atrial ventricular junction remodelingGO:000329420.017
synaptic growth at neuromuscular junctionGO:005112420.016
regulation of autophagyGO:001050630.016
response to stressGO:00069502630.016
nucleocytoplasmic transportGO:000691340.016
photoreceptor cell fate specificationGO:004370410.016
photoreceptor cell developmentGO:0042461400.016
multicellular organism growthGO:003526440.016
neuroblast differentiationGO:001401610.016
notochord developmentGO:0030903540.016
lipid catabolic processGO:001604240.016
central nervous system developmentGO:00074173870.016
response to mechanical stimulusGO:0009612240.016
gene expressionGO:00104672520.016
muscle fiber developmentGO:0048747520.016
positive regulation of stem cell proliferationGO:200064810.015
muscle organ developmentGO:00075171010.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
cardiac muscle cell contractionGO:008600310.015
establishment of protein localization to organelleGO:007259440.015
regulation of sodium ion transportGO:000202820.015
regulation of cell migration involved in sprouting angiogenesisGO:009004930.015
nephron tubule morphogenesisGO:007207810.015
dna templated transcription initiationGO:000635210.015
regulation of catalytic activityGO:0050790550.015
regulation of wound healingGO:006104120.015
embryo development ending in birth or egg hatchingGO:00097922710.015
renal system vasculature developmentGO:006143720.015
regulation of cellular amino acid metabolic processGO:000652100.015
regulation of cytoplasmic transportGO:190364940.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
regulation of cell differentiationGO:00455951420.015
regulation of reproductive processGO:200024140.015
negative regulation of mapk cascadeGO:004340940.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
regulation of protein catabolic processGO:004217610.014
cellular ketone metabolic processGO:0042180110.014
stem cell proliferationGO:007208940.014
positive regulation of cytokine productionGO:000181920.014
atp catabolic processGO:000620040.014
cellular biosynthetic processGO:00442492860.014
proteasomal protein catabolic processGO:001049820.014
negative regulation of cell deathGO:0060548600.014
behaviorGO:0007610740.014
atrioventricular valve formationGO:000319030.014
neuronal action potentialGO:0019228180.014
lipid oxidationGO:003444010.014
maintenance of locationGO:005123540.014
negative regulation of signal transductionGO:0009968940.014
regulation of cell deathGO:00109411030.014
blood vessel developmentGO:00015682460.013
rna localizationGO:000640340.013
cellular amine metabolic processGO:004410620.013
renal tubule morphogenesisGO:006133310.013
phosphorus metabolic processGO:00067931090.013
establishment of blood brain barrierGO:006085620.013
head developmentGO:00603223030.013
eye morphogenesisGO:00485921440.013
regulation of cell proliferation involved in heart morphogenesisGO:200013620.013
cellular response to biotic stimulusGO:007121630.013
eye developmentGO:00016542770.013
vasculature developmentGO:00019442780.013
microtubule organizing center organizationGO:003102310.013
cognitionGO:005089010.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
glucose importGO:004632320.013
meiotic cell cycle processGO:190304630.013
peptide transportGO:001583310.013
nuclear transportGO:005116940.013
pericardium morphogenesisGO:000334410.013
regulation of cellular component organizationGO:0051128860.013
bmp signaling pathwayGO:0030509520.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
negative regulation of metabolic processGO:0009892860.012
eye photoreceptor cell differentiationGO:0001754450.012
positive regulation of cellular catabolic processGO:003133130.012
mitotic cell cycleGO:0000278640.012
swimming behaviorGO:003626980.012
positive regulation of macromolecule metabolic processGO:0010604930.012
negative regulation of protein kinase activityGO:000646940.012
aromatic compound biosynthetic processGO:00194382170.012
regulation of nucleotide catabolic processGO:003081120.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
cellular metal ion homeostasisGO:0006875160.012
regulation of protein localization to nucleusGO:190018020.012
regulation of neurotransmitter secretionGO:004692810.012
regulation of organelle assemblyGO:190211540.012
phosphate containing compound metabolic processGO:00067961080.012
gtp catabolic processGO:000618420.012
cellular response to oxygen levelsGO:007145310.012
nucleobase containing compound biosynthetic processGO:00346542050.012
posterior lateral line neuromast developmentGO:0048919200.012
regulation of bindingGO:005109830.012
negative regulation of multicellular organismal processGO:0051241690.012
organic substance transportGO:0071702580.012
gtp metabolic processGO:004603940.012
homeostatic processGO:00425921420.012
endocardial cushion formationGO:000327220.011
protein importGO:001703830.011
negative regulation of signalingGO:0023057960.011
regulation of heart growthGO:006042020.011
guanosine containing compound metabolic processGO:190106840.011
fatty acid beta oxidationGO:000663510.011
regulation of cytokine productionGO:000181730.011
nephron epithelium morphogenesisGO:007208810.011
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082340.011
chemical homeostasisGO:0048878490.011
response to drugGO:004249330.011
response to topologically incorrect proteinGO:003596620.011
sex determinationGO:000753010.011
macromolecule modificationGO:00434121110.011
heart valve developmentGO:0003170140.011
locomotor rhythmGO:004547530.011
outflow tract morphogenesisGO:000315110.011
specification of organ positionGO:001015930.011
regulation of cell activationGO:005086510.011
regulation of dna replicationGO:000627530.011
phagocytosisGO:000690930.011
morphogenesis of an epithelial foldGO:006057110.011
positive regulation of metabolic processGO:00098931080.011
negative regulation of cell communicationGO:0010648960.011
multi organism reproductive processGO:0044703360.011
peripheral nervous system neuron differentiationGO:0048934280.011
notochord cell differentiationGO:0060034180.011
small molecule catabolic processGO:004428230.011
regulation of glial cell proliferationGO:006025140.011
cell substrate adhesionGO:003158940.011
invagination involved in gastrulation with mouth forming secondGO:005510910.011
cellular protein catabolic processGO:004425740.011
positive regulation of jak stat cascadeGO:004642720.011
regulation of receptor mediated endocytosisGO:004825940.010
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.010
cellular protein metabolic processGO:00442671290.010
mitotic cytokinesisGO:000028130.010
negative regulation of programmed cell deathGO:0043069580.010
detection of mechanical stimulusGO:0050982110.010
protein secretionGO:000930610.010
cation homeostasisGO:0055080330.010
cellular response to external stimulusGO:007149620.010
response to hydrogen peroxideGO:004254230.010
sleepGO:003043110.010
positive regulation of cellular biosynthetic processGO:0031328680.010
regulation of primary metabolic processGO:00800903110.010
negative regulation of oxidative stress induced cell deathGO:190320220.010
renal system vasculature morphogenesisGO:006143810.010
response to light stimulusGO:0009416460.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.010
compound eye developmentGO:004874920.010
cellular response to stressGO:0033554620.010
circadian sleep wake cycle processGO:002241020.010

scn12ab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.148
nervous system diseaseDOID:86300.040
musculoskeletal system diseaseDOID:1700.026
intrinsic cardiomyopathyDOID:006003600.026
muscle tissue diseaseDOID:6600.026
cardiomyopathyDOID:005070000.026
cardiovascular system diseaseDOID:128700.026
muscular diseaseDOID:008000000.026
hypertrophic cardiomyopathyDOID:1198400.026
heart diseaseDOID:11400.026
myopathyDOID:42300.026