Danio rerio

67 known processes

six1b

sine oculis homeobox homolog 1b

(Aliases: zgc:77345,MGC77345,six1)

six1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular macromolecule biosynthetic processGO:20001122220.999
Human Zebrafish Mouse Fly
regulation of nitrogen compound metabolic processGO:00511712510.998
Human Zebrafish Mouse Fly
organic substance biosynthetic processGO:19015762890.990
Human Zebrafish Mouse Fly
regulation of metabolic processGO:00192223590.988
Human Zebrafish Mouse Fly
rna biosynthetic processGO:00327741810.960
Human Zebrafish Mouse Fly
central nervous system developmentGO:00074173870.958
cellular aromatic compound metabolic processGO:00067252950.956
Human Zebrafish Mouse Fly
striated muscle cell differentiationGO:00511461290.951
nucleobase containing compound biosynthetic processGO:00346542050.950
Human Zebrafish Mouse Fly
regulation of gene expressionGO:00104682650.933
Human Zebrafish Mouse Fly
cellular nitrogen compound metabolic processGO:00346412900.926
Human Zebrafish Mouse Fly
regulation of biosynthetic processGO:00098892500.918
Human Zebrafish Mouse Fly
cellular nitrogen compound biosynthetic processGO:00442712180.915
Human Zebrafish Mouse Fly
macromolecule biosynthetic processGO:00090592270.904
Human Zebrafish Mouse Fly
inner ear developmentGO:00488391260.903
nucleic acid templated transcriptionGO:00976591810.877
Human Zebrafish Mouse Fly
generation of neuronsGO:00486993850.865
regulation of mechanoreceptor differentiationGO:004563110.850
Zebrafish
regulation of rna metabolic processGO:00512522240.849
Human Zebrafish Mouse Fly
regulation of macromolecule biosynthetic processGO:00105562250.840
Human Zebrafish Mouse Fly
regulation of nucleobase containing compound metabolic processGO:00192192500.838
Human Zebrafish Mouse Fly
regulation of cellular metabolic processGO:00313233200.837
Human Zebrafish Mouse Fly
localization of cellGO:00516742440.835
Mouse Fly
organic cyclic compound metabolic processGO:19013603010.830
Human Zebrafish Mouse Fly
posterior lateral line system developmentGO:0048915460.817
somatic muscle developmentGO:000752540.812
positive regulation of nitrogen compound metabolic processGO:0051173690.801
Human Mouse Fly
cellular biosynthetic processGO:00442492860.799
Human Zebrafish Mouse Fly
muscle contractionGO:0006936180.796
biosynthetic processGO:00090582940.795
Human Zebrafish Mouse Fly
aromatic compound biosynthetic processGO:00194382170.787
Human Zebrafish Mouse Fly
pharyngeal muscle developmentGO:004328240.778
heterocycle biosynthetic processGO:00181302150.758
Human Zebrafish Mouse Fly
nitrogen compound metabolic processGO:00068073190.752
Human Zebrafish Mouse Fly
regulation of rna biosynthetic processGO:20011412130.749
Human Zebrafish Mouse Fly
neuron developmentGO:00486662620.742
regulation of cellular biosynthetic processGO:00313262450.734
Human Zebrafish Mouse Fly
heterocycle metabolic processGO:00464832900.718
Human Zebrafish Mouse Fly
regulation of cell proliferation involved in heart morphogenesisGO:200013620.713
Mouse
positive regulation of cellular biosynthetic processGO:0031328680.696
Human Mouse Fly
cellular macromolecule metabolic processGO:00442603910.676
Human Zebrafish Mouse Fly
endocrine system developmentGO:0035270650.668
muscle tissue developmentGO:00605371100.660
cellular macromolecule biosynthetic processGO:00346452240.629
Human Zebrafish Mouse Fly
skeletal muscle organ developmentGO:0060538780.624
myotube differentiationGO:0014902450.619
embryo development ending in birth or egg hatchingGO:00097922710.611
Mouse
chemotaxisGO:00069351040.601
regulation of stem cell proliferationGO:007209120.596
Mouse
positive regulation of tyrosine phosphorylation of stat3 proteinGO:004251710.568
gene expressionGO:00104672520.567
Human Zebrafish Mouse Fly
larval developmentGO:000216420.567
cellular component movementGO:00069283350.555
Mouse Fly
hair cell differentiationGO:0035315320.523
posterior lateral line developmentGO:0048916380.522
posterior lateral line neuromast developmentGO:0048919200.498
neuron projection developmentGO:00311751800.494
positive regulation of nucleobase containing compound metabolic processGO:0045935690.487
Human Mouse Fly
regulation of neuron migrationGO:200122220.480
pituitary gland developmentGO:0021983160.479
somitogenesisGO:0001756870.479
mechanosensory lateral line system developmentGO:0048881490.464
reproductive processGO:0022414400.461
Fly
organic cyclic compound biosynthetic processGO:19013622230.456
Human Zebrafish Mouse Fly
striated muscle myosin thick filament assemblyGO:007168860.442
forebrain developmentGO:0030900960.438
atp catabolic processGO:000620040.428
muscle cell developmentGO:00550011150.423
axon developmentGO:00615641660.421
transcription from rna polymerase ii promoterGO:0006366800.417
Human Zebrafish Mouse Fly
muscle structure developmentGO:00610611960.415
transcription dna templatedGO:00063511810.415
Human Zebrafish Mouse Fly
regulation of primary metabolic processGO:00800903110.415
Human Zebrafish Mouse Fly
autonomic nervous system developmentGO:0048483190.413
Mouse
regulation of vitamin metabolic processGO:003065660.399
muscle system processGO:0003012200.391
nucleobase containing compound metabolic processGO:00061392740.391
Human Zebrafish Mouse Fly
neuron projection guidanceGO:0097485860.384
ventricular cardiac muscle tissue morphogenesisGO:005501020.375
skeletal muscle thin filament assemblyGO:003024040.372
heart morphogenesisGO:00030071560.367
Mouse
sensory organ developmentGO:00074233930.359
negative regulation of signal transduction in absence of ligandGO:190109910.355
extraocular skeletal muscle developmentGO:000207430.352
lateral line developmentGO:0048882660.351
ameboidal type cell migrationGO:00016671430.338
cell migrationGO:00164772370.334
Mouse Fly
rna metabolic processGO:00160702190.318
Human Zebrafish Mouse Fly
epithelial cell differentiationGO:00308551160.314
Mouse
sensory system developmentGO:0048880760.299
auditory receptor cell fate commitmentGO:000991240.297
positive regulation of cellular processGO:00485222010.286
Human Mouse Fly
nucleic acid metabolic processGO:00903042440.273
Human Zebrafish Mouse Fly
chordate embryonic developmentGO:00430092710.271
Mouse
cellular component morphogenesisGO:00329893360.269
stem cell proliferationGO:007208940.266
Mouse
cell morphogenesis involved in neuron differentiationGO:00486671630.258
positive regulation of rna metabolic processGO:0051254590.257
Human Mouse Fly
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.256
myotube cell developmentGO:0014904350.255
cell fate commitmentGO:0045165990.255
Mouse
regulation of inner ear receptor cell differentiationGO:200098010.248
Zebrafish
small molecule metabolic processGO:0044281770.243
signal transductionGO:00071654550.243
regulation of neuron differentiationGO:0045664560.242
Zebrafish Mouse
adenohypophysis developmentGO:0021984150.238
pigment cell developmentGO:007028530.230
positive regulation of rna biosynthetic processGO:1902680570.229
Human Mouse Fly
positive regulation of biological processGO:00485182530.225
Human Mouse Fly
regulation of chemotaxisGO:0050920180.225
positive regulation of metabolic processGO:00098931080.221
Human Mouse Fly
multicellular organism reproductionGO:0032504350.218
Fly
nephron morphogenesisGO:007202820.215
Mouse
neuromast developmentGO:0048884460.214
actin filament organizationGO:0007015150.213
diencephalon developmentGO:0021536580.210
retina development in camera type eyeGO:00600411460.208
axon guidanceGO:0007411860.207
organelle localizationGO:0051640490.204
positive regulation of notch signaling pathwayGO:004574730.202
cell migration in hindbrainGO:002153570.202
myofibril assemblyGO:0030239480.202
regulation of epithelial cell proliferationGO:005067830.194
Mouse
locomotionGO:00400113130.188
Mouse Fly
innervationGO:006038430.188
regionalizationGO:00030022740.187
Mouse
cell proliferationGO:0008283800.185
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.185
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.184
axonal fasciculationGO:0007413110.182
regulation of extrinsic apoptotic signaling pathwayGO:200123630.181
posterior lateral line neuromast hair cell differentiationGO:004892380.180
ribonucleoside monophosphate catabolic processGO:000915840.175
behaviorGO:0007610740.173
embryonic organ morphogenesisGO:00485622740.172
Zebrafish Mouse
regulation of collateral sproutingGO:004867070.172
muscle fiber developmentGO:0048747520.170
venous blood vessel developmentGO:006084190.169
negative regulation of nitrogen compound metabolic processGO:0051172590.168
Mouse
otolith developmentGO:0048840320.165
regulation of macromolecule metabolic processGO:00602553170.164
Human Zebrafish Mouse Fly
canonical wnt signaling pathwayGO:0060070480.163
muscle organ developmentGO:00075171010.162
embryonic epithelial tube formationGO:0001838170.161
Mouse
mechanoreceptor differentiationGO:0042490370.155
Zebrafish
positive regulation of biosynthetic processGO:0009891680.154
Human Mouse Fly
cell projection organizationGO:00300302840.150
negative regulation of canonical wnt signaling pathwayGO:0090090210.150
fin developmentGO:0033333770.149
regulation of cell developmentGO:00602841000.149
Zebrafish Mouse
central nervous system neuron differentiationGO:0021953740.147
neuroblast proliferationGO:000740520.144
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.143
purine nucleoside monophosphate catabolic processGO:000912840.143
muscle cell differentiationGO:00426921390.142
cell morphogenesisGO:00009022890.142
positive regulation of nucleic acid templated transcriptionGO:1903508570.139
Human Mouse Fly
organonitrogen compound metabolic processGO:1901564740.139
epidermal cell differentiationGO:0009913360.138
positive regulation of transcription dna templatedGO:0045893570.138
Human Mouse Fly
regulation of neurogenesisGO:0050767870.137
Zebrafish Mouse
extrinsic apoptotic signaling pathwayGO:009719130.137
cell morphogenesis involved in differentiationGO:00009041950.135
skin developmentGO:0043588540.135
positive regulation of stem cell proliferationGO:200064810.135
Mouse
multicellular organismal reproductive processGO:0048609350.134
Fly
collateral sproutingGO:004866890.134
photoreceptor cell fate specificationGO:004370410.134
brain developmentGO:00074202930.133
cell cycle processGO:0022402530.132
positive regulation of cell proliferationGO:0008284150.132
Mouse
axonogenesisGO:00074091520.131
venous blood vessel morphogenesisGO:004884530.131
embryonic organ developmentGO:00485683810.131
Zebrafish Mouse
signal transduction in absence of ligandGO:003803410.130
peripheral nervous system developmentGO:0007422550.127
divalent inorganic cation transportGO:0072511210.126
neural crest cell migrationGO:0001755420.122
regulation of anatomical structure morphogenesisGO:00226031300.119
Mouse
neuron differentiationGO:00301823530.117
somite specificationGO:0001757120.117
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.116
Human Mouse Fly
pharynx developmentGO:006046550.114
regulation of heart growthGO:006042020.113
regulation of nucleic acid templated transcriptionGO:19035062130.110
Human Zebrafish Mouse Fly
regulation of retinoic acid biosynthetic processGO:190005260.108
nephron tubule morphogenesisGO:007207810.106
Mouse
segment specificationGO:0007379120.105
digestive tract developmentGO:00485652650.105
regulation of muscle contractionGO:000693730.102
digestive system developmentGO:00551232890.102
sensory organ morphogenesisGO:00905962000.102
Zebrafish Mouse Fly
lateral line system developmentGO:0048925760.101
calcium ion transportGO:0006816180.099
neuron recognitionGO:0008038180.099
face developmentGO:006032480.096
cellular response to retinoic acidGO:007130010.094
preganglionic parasympathetic nervous system developmentGO:002178360.094
Mouse
nucleoside monophosphate catabolic processGO:000912540.092
neuromuscular process controlling balanceGO:005088530.090
mesodermal cell fate commitmentGO:0001710140.089
ossificationGO:0001503230.087
radial glial cell differentiationGO:006001920.086
aorta morphogenesisGO:003590930.085
Mouse
otic vesicle developmentGO:0071599420.083
Mouse
skeletal muscle tissue developmentGO:0007519670.083
release of sequestered calcium ion into cytosolGO:005120930.082
regulation of transcription dna templatedGO:00063552130.082
Human Zebrafish Mouse Fly
morphogenesis of an epitheliumGO:00020093330.082
Mouse
regulation of response to stimulusGO:00485832690.081
cell surface receptor signaling pathwayGO:00071663250.081
negative regulation of wnt signaling pathwayGO:0030178300.081
inner ear receptor cell fate commitmentGO:006012040.079
cell motilityGO:00488702440.079
Mouse Fly
aorta developmentGO:003590440.079
Mouse
establishment or maintenance of cell polarityGO:0007163290.078
post embryonic organ developmentGO:004856940.077
purine ribonucleoside monophosphate catabolic processGO:000916940.074
inner ear morphogenesisGO:0042472630.073
Mouse
phosphorus metabolic processGO:00067931090.072
fin morphogenesisGO:0033334530.072
regulation of developmental processGO:00507932470.072
Zebrafish Mouse
negative regulation of cellular processGO:00485232830.069
Mouse
regulation of purine nucleotide catabolic processGO:003312120.069
spinal cord developmentGO:0021510460.068
anatomical structure homeostasisGO:0060249360.067
epidermis developmentGO:0008544480.066
camera type eye morphogenesisGO:00485931080.066
Zebrafish
olfactory placode morphogenesisGO:007169970.065
Mouse
regulation of organ growthGO:004662030.065
mesoderm developmentGO:0007498880.065
negative regulation of macromolecule metabolic processGO:0010605760.064
Mouse
cellular ion homeostasisGO:0006873170.063
divalent metal ion transportGO:0070838200.063
striated muscle cell developmentGO:00550021080.062
retinal rod cell developmentGO:004654840.062
body morphogenesisGO:0010171160.061
regulation of retina development in camera type eyeGO:190286620.061
nephron epithelium morphogenesisGO:007208810.061
Mouse
regulation of canonical wnt signaling pathwayGO:0060828340.061
regulation of nucleoside metabolic processGO:000911820.060
epithelial tube formationGO:0072175190.059
Mouse
actin cytoskeleton organizationGO:0030036630.059
midbrain developmentGO:0030901280.058
central nervous system myelinationGO:002201020.058
auditory receptor cell developmentGO:006011780.057
glial cell fate determinationGO:000740310.056
positive regulation of gene expressionGO:0010628710.056
Human Mouse Fly
single organism organelle organizationGO:19025891990.056
regulation of heart contractionGO:0008016320.056
mesodermal cell fate specificationGO:0007501120.055
immune system processGO:00023762410.055
Mouse
neuromast hair cell differentiationGO:0048886120.055
embryonic viscerocranium morphogenesisGO:0048703520.054
apoptotic processGO:00069151160.054
Mouse
anterior posterior pattern specificationGO:00099521520.054
dorsal ventral pattern formationGO:00099531250.053
cell recognitionGO:0008037190.053
response to mechanical stimulusGO:0009612240.053
peripheral nervous system neuron differentiationGO:0048934280.052
positive regulation of cellular metabolic processGO:0031325940.052
Human Mouse Fly
cerebellar granular layer formationGO:002168430.052
multi organism processGO:00517041340.052
Fly
xanthophore differentiationGO:005093630.052
multicellular organism growthGO:003526440.051
skeletal system morphogenesisGO:00487051020.051
Mouse
notch signaling pathwayGO:0007219350.051
glial cell migrationGO:000834730.050
Fly
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.050
negative regulation of biological processGO:00485193040.050
Mouse
regulation of mesodermal cell fate specificationGO:004266190.050
cellular amino acid metabolic processGO:000652070.050
developmental programmed cell deathGO:001062340.048
epithelial tube morphogenesisGO:00605621480.048
Mouse
negative regulation of macromolecule biosynthetic processGO:0010558480.047
Mouse
i kappab phosphorylationGO:000725210.047
neuronal stem cell maintenanceGO:009715020.047
cellular component assembly involved in morphogenesisGO:00109271070.047
cytoskeleton organizationGO:0007010960.047
primary neural tube formationGO:001402010.046
smooth muscle contractionGO:000693920.045
cell proliferation involved in heart morphogenesisGO:006132320.045
Mouse
innate immune responseGO:0045087130.045
gastrulationGO:00073692080.044
nucleotide metabolic processGO:0009117280.044
blood vessel developmentGO:00015682460.044
Mouse
establishment of cell polarityGO:0030010180.043
development of primary female sexual characteristicsGO:004654540.043
homeostatic processGO:00425921420.043
positive regulation of cell fate commitmentGO:001045510.042
regulation of multicellular organismal developmentGO:20000262230.042
Zebrafish Mouse
response to stressGO:00069502630.042
Zebrafish
morphogenesis of an epithelial sheetGO:0002011490.039
ear developmentGO:00435831270.039
detection of chemical stimulusGO:000959340.039
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.038
Mouse
peptidyl tyrosine dephosphorylationGO:003533510.038
sprouting angiogenesisGO:0002040530.038
appendage developmentGO:0048736800.038
cell migration involved in gastrulationGO:0042074790.038
embryonic cranial skeleton morphogenesisGO:0048701900.038
Mouse
cation transportGO:0006812810.037
regulation of sarcomere organizationGO:006029720.037
microtubule based processGO:0007017600.037
camera type eye developmentGO:00430102220.037
gabaergic neuron differentiationGO:009715420.037
myosin filament organizationGO:003103360.036
skeletal muscle fiber developmentGO:0048741350.035
retinoic acid biosynthetic processGO:000213860.035
positive regulation of neurogenesisGO:0050769240.035
negative regulation of axon guidanceGO:190266810.035
transmission of nerve impulseGO:0019226190.035
kidney morphogenesisGO:0060993150.034
Mouse
proepicardium developmentGO:000334240.034
actin filament based processGO:0030029640.034
morphogenesis of a branching structureGO:0001763210.034
Mouse
tongue morphogenesisGO:004358730.034
Mouse
oxoacid metabolic processGO:0043436310.034
somite developmentGO:0061053960.034
Mouse
skeletal myofibril assemblyGO:001486670.034
biological adhesionGO:0022610400.033
regulation of biological qualityGO:00650082630.033
Mouse
regulation of epidermis developmentGO:004568220.033
positive regulation of cytosolic calcium ion concentrationGO:000720440.033
striated muscle tissue developmentGO:00147061100.033
striated muscle cell proliferationGO:001485570.033
proximal distal pattern formationGO:000995410.033
axon regenerationGO:0031103140.033
negative regulation of developmental processGO:0051093650.032
Mouse
programmed cell deathGO:00125011190.032
Mouse
taxisGO:00423301090.032
epidermal cell fate specificationGO:000995740.032
forebrain generation of neuronsGO:0021872140.032
regulation of nucleotide catabolic processGO:003081120.032
cardiac atrium developmentGO:000323040.032
angiogenesisGO:00015251580.032
detection of mechanical stimulusGO:0050982110.032
sympathetic ganglion developmentGO:006154920.031
muscle cell migrationGO:001481240.031
Mouse
wnt signaling pathwayGO:0016055800.031
neuron migrationGO:0001764220.031
regulation of hydrolase activityGO:0051336280.031
cytokinesisGO:000091030.031
cardiac muscle tissue morphogenesisGO:005500870.030
retinoic acid metabolic processGO:004257390.030
regulation of calcium ion transportGO:005192420.030
regulation of cellular component movementGO:0051270550.030
vasculature developmentGO:00019442780.030
Mouse
chemical homeostasisGO:0048878490.029
embryonic skeletal system developmentGO:0048706970.029
Mouse
retina morphogenesis in camera type eyeGO:0060042790.029
neural retina developmentGO:0003407490.029
regulation of tyrosine phosphorylation of stat proteinGO:004250910.029
regulation of locomotionGO:0040012550.028
negative regulation of signal transductionGO:0009968940.028
organic cyclic compound catabolic processGO:1901361150.028
system processGO:00030081850.028
Mouse
head developmentGO:00603223030.028
neuromast depositionGO:004888590.028
response to axon injuryGO:0048678140.027
response to chemicalGO:00422213200.027
regulation of axon extensionGO:0030516240.027
stem cell fate determinationGO:004886710.027
negative regulation of chemotaxisGO:005092240.026
neuroblast differentiationGO:001401610.026
regulation of cellular amino acid metabolic processGO:000652100.026
regulation of nervous system developmentGO:0051960900.026
Zebrafish Mouse
apoptotic process involved in morphogenesisGO:006056120.026
cytosolic calcium ion transportGO:006040130.026
homeostasis of number of cellsGO:0048872620.026
mitotic cell cycleGO:0000278640.025
regulation of mesoderm developmentGO:2000380110.025
positive regulation of tyrosine phosphorylation of stat proteinGO:004253110.025
positive regulation of developmental processGO:0051094500.025
Mouse
sensory perceptionGO:0007600390.025
Mouse
regulation of cell migrationGO:0030334400.025
embryonic skeletal system morphogenesisGO:0048704930.025
Mouse
cerebellar granule cell differentiationGO:002170730.024
negative regulation of cell communicationGO:0010648960.024
regulation of transcription from rna polymerase ii promoterGO:00063571140.024
Human Zebrafish Mouse Fly
carbohydrate derivative metabolic processGO:1901135610.023
alcohol biosynthetic processGO:004616520.023
cerebellar granular layer morphogenesisGO:002168330.023
regulation of notch signaling pathwayGO:0008593160.023
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
hindbrain developmentGO:0030902910.022
embryonic eye morphogenesisGO:0048048300.022
Zebrafish
regulation of axonogenesisGO:0050770320.022
regulation of phosphate metabolic processGO:0019220430.022
auditory receptor cell differentiationGO:0042491150.022
septum transversum developmentGO:000334340.022
embryonic heart tube developmentGO:00350501330.022
cell differentiation in spinal cordGO:0021515400.022
neuron fate specificationGO:0048665200.022
Mouse
diterpenoid biosynthetic processGO:001610270.022
gtp catabolic processGO:000618420.021
regulation of cell differentiationGO:00455951420.021
Zebrafish Mouse
lamellipodium assemblyGO:003003210.021
atp metabolic processGO:004603450.021
digestive tract morphogenesisGO:00485462310.021
response to activityGO:0014823140.021
negative regulation of biosynthetic processGO:0009890550.020
Mouse
neural crest cell developmentGO:0014032620.020
melanin metabolic processGO:000658220.020
response to woundingGO:00096111160.020
Zebrafish
organic acid metabolic processGO:0006082310.020
stem cell fate commitmentGO:004886510.020
hypochord developmentGO:005501630.020
positive regulation of macromolecule biosynthetic processGO:0010557590.020
Human Mouse Fly
positive regulation of striated muscle cell differentiationGO:005115510.019
single organism biosynthetic processGO:0044711710.019
ribonucleotide metabolic processGO:0009259270.019
camera type eye photoreceptor cell differentiationGO:0060219190.019
olfactory placode formationGO:003091010.019
Mouse
muscle cell fate determinationGO:000752110.019
neuroblast fate determinationGO:000740010.019
regulation of cell shapeGO:000836010.019
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.019
auditory receptor cell fate specificationGO:004266720.019
neural crest cell differentiationGO:0014033720.019
regulation of skeletal muscle fiber developmentGO:004874220.019
positive regulation of cellular amine metabolic processGO:003324000.019
positive regulation of nervous system developmentGO:0051962250.019
mesodermal cell differentiationGO:0048333210.019
developmental growth involved in morphogenesisGO:0060560860.019
Mouse
enteric nervous system developmentGO:0048484120.019
negative regulation of endothelial cell migrationGO:001059610.019
response to external stimulusGO:00096052640.019
Fly
regulation of axon extension involved in axon guidanceGO:004884160.019
pigment cell differentiationGO:0050931380.019
antimicrobial humoral responseGO:001973020.019
positive regulation of cell motilityGO:2000147110.019
positive regulation of cell migrationGO:0030335110.019
blood vessel morphogenesisGO:00485142160.018
Mouse
protein dephosphorylationGO:000647030.018
blood circulationGO:0008015870.018
head morphogenesisGO:006032380.018
epithelial cell proliferationGO:0050673170.018
Mouse
apoptotic process involved in developmentGO:190274220.018
myoblast fusionGO:0007520100.018
kidney developmentGO:0001822920.018
Zebrafish Mouse
regulation of signal transductionGO:00099662250.018
regulation of cell morphogenesis involved in differentiationGO:0010769380.018
female sex differentiationGO:004666040.018
positive regulation of programmed cell deathGO:0043068290.018
regulation of carbohydrate metabolic processGO:000610940.018
exocrine system developmentGO:0035272280.017
epithelial cell morphogenesisGO:000338220.017
outflow tract morphogenesisGO:000315110.017
Mouse
positive regulation of epithelial cell proliferationGO:005067910.017
reactive nitrogen species metabolic processGO:200105700.017
sensory epithelium regenerationGO:0070654140.017
Zebrafish
posterior lateral line neuromast depositionGO:004892250.017
negative regulation of collateral sproutingGO:004867120.017
embryonic camera type eye morphogenesisGO:0048596190.017
Zebrafish
neuron projection morphogenesisGO:00488121610.017
cell substrate adhesionGO:003158940.017
skeletal system developmentGO:00015011810.017
Mouse
positive regulation of neural precursor cell proliferationGO:200017910.016
regulation of ectodermal cell fate specificationGO:004266520.016
negative regulation of axon extensionGO:003051770.016
positive regulation of response to stimulusGO:0048584800.016
collateral sprouting in absence of injuryGO:004866940.016
nucleoside phosphate metabolic processGO:0006753280.016
regulation of phosphorus metabolic processGO:0051174430.016
forebrain neuron fate commitmentGO:002187710.016
single organism reproductive processGO:0044702400.016
Fly
cell cycleGO:0007049930.016
cellular ketone metabolic processGO:0042180110.016
axon extension involved in axon guidanceGO:0048846100.016
negative regulation of neuron projection regenerationGO:007057140.016
aromatic compound catabolic processGO:0019439150.016
secondary metabolic processGO:001974830.015
forebrain cell migrationGO:002188510.015
ectodermal cell fate specificationGO:000171520.015
neuron projection regenerationGO:0031102160.015
renal tubule morphogenesisGO:006133310.015
Mouse
establishment of mitotic spindle localizationGO:0040001120.015
tube closureGO:006060610.015

six1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
auditory system diseaseDOID:274200.852
Human
autosomal dominant nonsyndromic deafnessDOID:005056400.852
Human
nervous system diseaseDOID:86300.852
Human
nonsyndromic deafnessDOID:005056300.852
Human
disease of anatomical entityDOID:700.852
Human
sensory system diseaseDOID:005015500.852
Human
musculoskeletal system diseaseDOID:1700.030
thyroid cancerDOID:178100.027
organ system cancerDOID:005068600.027
endocrine gland cancerDOID:17000.027
cancerDOID:16200.027
disease of cellular proliferationDOID:1456600.027
eye and adnexa diseaseDOID:149200.016
eye diseaseDOID:561400.016
heart diseaseDOID:11400.016
cardiovascular system diseaseDOID:128700.016