Danio rerio

0 known processes

ddi2

DNA-damage inducible protein 2

(Aliases: zgc:63515)

ddi2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.092
agingGO:000756820.055
maintenance of locationGO:005123540.052
meiotic nuclear divisionGO:000712640.043
cellular protein catabolic processGO:004425740.042
establishment of protein localization to organelleGO:007259440.042
positive regulation of transportGO:005105020.041
cellular macromolecule metabolic processGO:00442603910.041
modification dependent protein catabolic processGO:001994130.040
ubiquitin dependent protein catabolic processGO:000651130.040
phagocytosisGO:000690930.039
proteolysis involved in cellular protein catabolic processGO:005160330.037
multicellular organism growthGO:003526440.036
nitrogen compound metabolic processGO:00068073190.035
nucleocytoplasmic transportGO:000691340.035
modification dependent macromolecule catabolic processGO:004363230.034
nuclear transportGO:005116940.034
lipid storageGO:001991510.034
proteasomal protein catabolic processGO:001049820.032
nucleic acid metabolic processGO:00903042440.031
regulation of multicellular organism growthGO:004001440.031
cellular nitrogen compound metabolic processGO:00346412900.031
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
heterocycle metabolic processGO:00464832900.030
amine metabolic processGO:000930820.029
single organism nuclear importGO:190259330.029
regulation of mrna processingGO:005068430.029
cellular amine metabolic processGO:004410620.029
biosynthetic processGO:00090582940.029
protein localization to nucleusGO:003450430.029
regulation of protein complex assemblyGO:004325430.028
regulation of metabolic processGO:00192223590.028
mitochondrion organizationGO:000700540.028
positive regulation of cellular component biogenesisGO:004408930.028
organic cyclic compound metabolic processGO:19013603010.028
nucleobase containing compound metabolic processGO:00061392740.028
regulation of establishment of protein localizationGO:007020140.027
nuclear importGO:005117030.027
endosomal transportGO:001619720.027
signal transductionGO:00071654550.026
cellular biosynthetic processGO:00442492860.026
protein importGO:001703830.026
single organism membrane fusionGO:004480120.026
neuron differentiationGO:00301823530.026
membrane fusionGO:006102520.026
cytokinesisGO:000091030.026
meiotic cell cycle processGO:190304630.025
regulation of mrna splicing via spliceosomeGO:004802430.025
positive regulation of catabolic processGO:000989640.025
regulation of protein transportGO:005122330.025
regulation of cytokine productionGO:000181730.025
negative regulation of protein phosphorylationGO:000193340.025
response to drugGO:004249330.025
regulation of protein ubiquitinationGO:003139630.024
gene expressionGO:00104672520.024
cellular aromatic compound metabolic processGO:00067252950.024
rna metabolic processGO:00160702190.024
organelle fusionGO:004828430.024
organic substance biosynthetic processGO:19015762890.024
regulation of protein catabolic processGO:004217610.024
regulation of cellular amine metabolic processGO:003323800.024
cellular macromolecule biosynthetic processGO:00346452240.024
locomotionGO:00400113130.024
cell part morphogenesisGO:00329902460.024
regulation of gene expressionGO:00104682650.024
regulation of protein targetingGO:190353320.024
regulation of cytoplasmic transportGO:190364940.023
regulation of macromolecule metabolic processGO:00602553170.023
regulation of protein modification by small protein conjugation or removalGO:190332030.023
protein import into nucleusGO:000660630.023
guanosine containing compound metabolic processGO:190106840.023
transportGO:00068102200.023
Fly
regulation of cellular metabolic processGO:00313233200.023
cellular ketone metabolic processGO:0042180110.023
protein targeting to nucleusGO:004474430.023
cell surface receptor signaling pathwayGO:00071663250.022
regulation of cell shapeGO:000836010.022
stem cell maintenanceGO:001982740.022
rna biosynthetic processGO:00327741810.022
response to stressGO:00069502630.022
protein metabolic processGO:00195381830.022
regulation of nucleocytoplasmic transportGO:004682220.022
regulation of meiotic cell cycleGO:005144510.022
meiotic chromosome segregationGO:004513230.022
gtp metabolic processGO:004603940.022
cellular component assemblyGO:00226071700.022
Worm
cellular component morphogenesisGO:00329893360.022
protein localization to plasma membraneGO:007265910.022
cellular amino acid metabolic processGO:000652070.022
cellular nitrogen compound biosynthetic processGO:00442712180.022
cell morphogenesisGO:00009022890.022
stem cell proliferationGO:007208940.021
regulation of cellular amino acid metabolic processGO:000652100.021
protein acylationGO:004354330.021
macromolecule biosynthetic processGO:00090592270.021
single organism organelle organizationGO:19025891990.021
guanosine containing compound catabolic processGO:190106920.021
cellular component disassemblyGO:002241110.021
cognitionGO:005089010.021
positive regulation of cell cycleGO:004578730.021
regulation of cellular ketone metabolic processGO:001056570.021
organelle organizationGO:00069962270.021
regulation of protein localization to nucleusGO:190018020.021
protein acetylationGO:000647320.020
i kappab kinase nf kappab signalingGO:000724940.020
regulation of primary metabolic processGO:00800903110.020
spermatid developmentGO:000728620.020
regulation of cellular biosynthetic processGO:00313262450.020
single organism transportGO:00447652060.020
Fly
cellular component movementGO:00069283350.020
internal protein amino acid acetylationGO:000647520.020
cellular response to external stimulusGO:007149620.020
immune system processGO:00023762410.020
gtp catabolic processGO:000618420.020
positive regulation of cellular catabolic processGO:003133130.020
regulation of signalingGO:00230512350.020
golgi vesicle transportGO:004819330.020
regulation of response to stimulusGO:00485832690.020
organic acid metabolic processGO:0006082310.020
regulation of cell activationGO:005086510.020
oxoacid metabolic processGO:0043436310.020
cell projection organizationGO:00300302840.019
positive regulation of translationGO:004572710.019
nucleobase containing compound biosynthetic processGO:00346542050.019
regulation of cell communicationGO:00106462320.019
peptidyl serine phosphorylationGO:001810510.019
establishment of localizationGO:00512342440.019
Fly
generation of neuronsGO:00486993850.019
carboxylic acid metabolic processGO:0019752220.019
cellular component biogenesisGO:00440851780.019
Worm
regulation of nitrogen compound metabolic processGO:00511712510.019
internal peptidyl lysine acetylationGO:001839320.019
central nervous system developmentGO:00074173870.019
tube morphogenesisGO:00352393490.019
regulation of protein import into nucleusGO:004230620.019
cellular response to lipopolysaccharideGO:007122230.019
organic cyclic compound biosynthetic processGO:19013622230.019
cellular respirationGO:004533330.019
response to external stimulusGO:00096052640.019
protein complex disassemblyGO:004324110.019
regulation of i kappab kinase nf kappab signalingGO:004312240.018
regulation of neural precursor cell proliferationGO:200017730.018
regulation of rna biosynthetic processGO:20011412130.018
phagocytosis engulfmentGO:000691110.018
positive regulation of biological processGO:00485182530.018
autophagyGO:000691440.018
cell projection morphogenesisGO:00488582440.018
regulation of signal transductionGO:00099662250.018
single organism localizationGO:19025782250.018
Fly
regulation of biological qualityGO:00650082630.018
Worm
regulation of biosynthetic processGO:00098892500.018
cellular protein metabolic processGO:00442671290.018
regulation of intracellular protein transportGO:003315730.018
single organism metabolic processGO:00447102170.018
small molecule metabolic processGO:0044281770.018
regulation of bindingGO:005109830.018
alternative mrna splicing via spliceosomeGO:000038010.018
erk1 and erk2 cascadeGO:007037140.018
peptidyl lysine acetylationGO:001839420.018
regulation of rna metabolic processGO:00512522240.018
negative regulation of biological processGO:00485193040.018
Worm
nucleoside monophosphate catabolic processGO:000912540.017
morphogenesis of an epitheliumGO:00020093330.017
regulation of alternative mrna splicing via spliceosomeGO:000038110.017
positive regulation of cellular amine metabolic processGO:003324000.017
symbiosis encompassing mutualism through parasitismGO:004440340.017
response to uvGO:000941130.017
cellular response to biotic stimulusGO:007121630.017
regulation of macromolecule biosynthetic processGO:00105562250.017
regulation of multicellular organismal processGO:00512392770.017
Worm
positive regulation of secretionGO:005104710.017
sensory organ developmentGO:00074233930.017
membrane invaginationGO:001032410.017
aromatic compound biosynthetic processGO:00194382170.017
regulation of synapse organizationGO:005080730.017
Worm
b cell activationGO:004211320.017
single fertilizationGO:000733830.017
macromolecular complex disassemblyGO:003298410.017
rna localizationGO:000640340.017
cell migrationGO:00164772370.017
extrinsic apoptotic signaling pathwayGO:009719130.017
nucleic acid templated transcriptionGO:00976591810.017
positive regulation of cytokine productionGO:000181920.017
negative regulation of cellular processGO:00485232830.016
Worm
protein dephosphorylationGO:000647030.016
cellular response to extracellular stimulusGO:003166820.016
ribonucleoside monophosphate catabolic processGO:000915840.016
cytoskeleton dependent cytokinesisGO:006164030.016
growthGO:00400071740.016
synaptic growth at neuromuscular junctionGO:005112420.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
adult behaviorGO:003053420.016
localization of cellGO:00516742440.016
positive regulation of protein complex assemblyGO:003133420.016
stem cell divisionGO:001714510.016
negative regulation of kinase activityGO:003367340.016
centrosome organizationGO:005129710.016
cellular response to starvationGO:000926710.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
microtubule organizing center organizationGO:003102310.016
double strand break repairGO:000630230.016
cellular response to molecule of bacterial originGO:007121930.016
negative regulation of catabolic processGO:000989530.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
cellular response to nutrient levelsGO:003166920.016
positive regulation of secretion by cellGO:190353210.015
cell motilityGO:00488702440.015
protein stabilizationGO:005082120.015
negative regulation of protein kinase activityGO:000646940.015
neuroblast proliferationGO:000740520.015
spermatid differentiationGO:004851520.015
nucleic acid transportGO:005065720.015
organonitrogen compound metabolic processGO:1901564740.015
transcription dna templatedGO:00063511810.015
cell matrix adhesionGO:000716040.015
positive regulation of cytoskeleton organizationGO:005149530.015
heterocycle biosynthetic processGO:00181302150.015
viral processGO:001603210.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
mitotic dna integrity checkpointGO:004477440.015
digestive system developmentGO:00551232890.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
production of molecular mediator of immune responseGO:000244020.015
cell cycle g1 s phase transitionGO:004484310.015
actin filament polymerizationGO:003004120.015
mitotic cell cycle embryonicGO:004544820.015
protein polyubiquitinationGO:000020940.015
exocytosisGO:000688710.015
leukocyte proliferationGO:007066110.015
transcription from rna polymerase ii promoterGO:0006366800.015
response to chemicalGO:00422213200.015
actin polymerization or depolymerizationGO:000815420.015
locomotor rhythmGO:004547530.015
neuron developmentGO:00486662620.015
positive regulation of cell activationGO:005086710.015
regulation of erk1 and erk2 cascadeGO:007037240.015
eye developmentGO:00016542770.015
g1 s transition of mitotic cell cycleGO:000008210.015
regulation of nucleoside metabolic processGO:000911820.015
cellular amide metabolic processGO:004360340.015
positive regulation of immune effector processGO:000269930.014
developmental growthGO:00485891660.014
protein secretionGO:000930610.014
regulation of gtpase activityGO:004308720.014
cellular response to light stimulusGO:007148240.014
protein polymerizationGO:005125840.014
peptidyl serine modificationGO:001820920.014
regulation of synaptic plasticityGO:004816710.014
interspecies interaction between organismsGO:004441940.014
regulation of developmental processGO:00507932470.014
Worm
regulation of nucleotide catabolic processGO:003081120.014
gastrulationGO:00073692080.014
response to topologically incorrect proteinGO:003596620.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
positive regulation of dna metabolic processGO:005105410.014
neuron projection morphogenesisGO:00488121610.014
positive regulation of cell adhesionGO:004578510.014
regulation of cellular protein catabolic processGO:190336210.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
immune system developmentGO:00025201910.014
regionalizationGO:00030022740.014
secondary metabolic processGO:001974830.014
regulation of stem cell proliferationGO:007209120.014
nuclear exportGO:005116810.014
rna transportGO:005065820.014
embryo development ending in birth or egg hatchingGO:00097922710.014
regulation of protein polymerizationGO:003227120.014
centrosome cycleGO:000709810.014
positive regulation of map kinase activityGO:004340630.013
cellular response to chemical stimulusGO:00708871570.013
heart developmentGO:00075073130.013
establishment of rna localizationGO:005123630.013
negative regulation of cellular catabolic processGO:003133030.013
vacuolar transportGO:000703420.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
atp catabolic processGO:000620040.013
cell substrate adhesionGO:003158940.013
translational initiationGO:000641330.013
macromolecule modificationGO:00434121110.013
regulation of autophagyGO:001050630.013
response to carbohydrateGO:000974330.013
negative regulation of mapk cascadeGO:004340940.013
negative regulation of cytokine productionGO:000181810.013
axonogenesisGO:00074091520.013
lateral inhibitionGO:004633110.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
negative regulation of defense responseGO:003134820.013
g2 dna damage checkpointGO:003157230.013
protein modification processGO:00362111000.013
regulation of synapse assemblyGO:005196330.013
Worm
hemopoiesisGO:00300971830.013
digestive tract morphogenesisGO:00485462310.013
system processGO:00030081850.013
cellular protein modification processGO:00064641000.013
determination of bilateral symmetryGO:00098552040.013
regulation of purine nucleotide catabolic processGO:003312120.013
negative regulation of protein complex assemblyGO:003133310.013
female gonad developmentGO:000858540.013
nucleobase containing compound transportGO:001593120.013
positive regulation of erk1 and erk2 cascadeGO:007037420.013
regulation of reproductive processGO:200024140.012
cellular response to radiationGO:007147840.012
chemosensory behaviorGO:000763510.012
sequestering of metal ionGO:005123830.012
response to hexoseGO:000974630.012
mitotic g2 m transition checkpointGO:004481830.012
regulation of organelle assemblyGO:190211540.012
embryonic organ morphogenesisGO:00485622740.012
regulation of response to biotic stimulusGO:000283120.012
regulation of inflammatory responseGO:005072720.012
vasculature developmentGO:00019442780.012
regulation of blood pressureGO:000821710.012
purine nucleoside monophosphate catabolic processGO:000912840.012
mononuclear cell proliferationGO:003294310.012
cellular carbohydrate metabolic processGO:004426240.012
cellular localizationGO:0051641970.012
brain developmentGO:00074202930.012
mitotic cytokinesisGO:000028130.012
negative regulation of response to stimulusGO:00485851040.012
development of primary female sexual characteristicsGO:004654540.012
lymphocyte proliferationGO:004665110.012
axon developmentGO:00615641660.012
rna export from nucleusGO:000640510.012
peptide transportGO:001583310.012
positive regulation of nucleotide catabolic processGO:003081310.012
head developmentGO:00603223030.012
regulation of cell projection assemblyGO:006049140.012
negative regulation of sequestering of calcium ionGO:005128340.012
regulation of gtp catabolic processGO:003312420.012
fertilizationGO:000956630.012
antimicrobial humoral responseGO:001973020.012
positive regulation of cellular processGO:00485222010.012
regulation of organ growthGO:004662030.012
female sex differentiationGO:004666040.012
germ line stem cell maintenanceGO:003071820.012
tissue remodelingGO:004877140.012
multi organism processGO:00517041340.012
Fly
intracellular signal transductionGO:0035556850.012
response to organic substanceGO:00100331530.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
negative regulation of nuclear divisionGO:005178430.011
establishment of protein localization to plasma membraneGO:009000210.011
somatic stem cell maintenanceGO:003501910.011
regulation of production of molecular mediator of immune responseGO:000270010.011
blood vessel developmentGO:00015682460.011
positive regulation of stress activated mapk cascadeGO:003287430.011
regulation of transcription dna templatedGO:00063552130.011
negative regulation of protein transportGO:005122430.011
establishment of synaptic vesicle localizationGO:009748010.011
regulation of metal ion transportGO:001095940.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.011
synaptic vesicle localizationGO:009747910.011
cellular response to organic substanceGO:00713101050.011
regulation of dna templated transcription elongationGO:003278430.011
post embryonic organ developmentGO:004856940.011
homeostatic processGO:00425921420.011
positive regulation of nucleoside metabolic processGO:004597910.011
positive regulation of gtp catabolic processGO:003312610.011
cell substrate junction assemblyGO:000704420.011
specification of symmetryGO:00097992040.011
somatic muscle developmentGO:000752540.011
sequestering of calcium ionGO:005120830.011
regulation of reactive oxygen species metabolic processGO:200037720.011
embryonic organ developmentGO:00485683810.011
dna templated transcription elongationGO:000635430.011
positive regulation of chromosome organizationGO:200125210.011
angiogenesisGO:00015251580.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
response to monosaccharideGO:003428430.011
positive regulation of leukocyte differentiationGO:190210710.011
mitochondrial transportGO:000683920.011
primary neural tube formationGO:001402010.011
intracellular mrna localizationGO:000829810.011
carbohydrate homeostasisGO:003350010.011
glucose homeostasisGO:004259310.011
camera type eye developmentGO:00430102220.011
multi organism cellular processGO:004476420.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
regulation of stem cell differentiationGO:200073640.011
meiosis iGO:000712710.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
compound eye developmentGO:004874920.011
cytosolic calcium ion transportGO:006040130.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
establishment of localization in cellGO:0051649770.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
protein homooligomerizationGO:005126030.011
regulation of protein complex disassemblyGO:004324410.011
ameboidal type cell migrationGO:00016671430.011
neuron projection developmentGO:00311751800.011
response to hydrogen peroxideGO:004254230.011
macroautophagyGO:001623610.011
mitotic g2 dna damage checkpointGO:000709530.011
positive regulation of ras protein signal transductionGO:004657910.011
cytoplasm organizationGO:000702840.011
calcium ion transport into cytosolGO:006040230.010
regulation of circadian rhythmGO:004275240.010
negative regulation of signal transductionGO:0009968940.010
negative regulation of cytoplasmic transportGO:190365020.010
lamellipodium assemblyGO:003003210.010
positive regulation of purine nucleotide catabolic processGO:003312310.010
synaptic vesicle transportGO:004848910.010
positive regulation of small gtpase mediated signal transductionGO:005105710.010
phosphate containing compound metabolic processGO:00067961080.010
muscle structure developmentGO:00610611960.010
negative regulation of chromosome organizationGO:200125110.010
regulation of sequestering of calcium ionGO:005128240.010
negative regulation of multi organism processGO:004390130.010
signal transduction in absence of ligandGO:003803410.010
positive regulation of gtpase activityGO:004354710.010
adherens junction organizationGO:003433240.010
negative regulation of macromolecule metabolic processGO:0010605760.010
digestive tract developmentGO:00485652650.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
organelle assemblyGO:00709251100.010
response to alkaloidGO:004327920.010
positive regulation of multi organism processGO:004390230.010
response to glucoseGO:000974930.010
positive regulation of notch signaling pathwayGO:004574730.010
positive regulation of protein polymerizationGO:003227320.010
spindle assemblyGO:005122520.010
determination of left right symmetryGO:00073681790.010
blood vessel morphogenesisGO:00485142160.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
post golgi vesicle mediated transportGO:000689210.010
liver developmentGO:0001889960.010

ddi2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.051
nervous system diseaseDOID:86300.024
musculoskeletal system diseaseDOID:1700.016
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.014
disease of metabolismDOID:001466700.012
cardiovascular system diseaseDOID:128700.012
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
muscular diseaseDOID:008000000.012
muscle tissue diseaseDOID:6600.011