Danio rerio

39 known processes

vcl

vinculin

(Aliases: im:6902790,hm:zehn2160)

vcl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.133
adherens junction organizationGO:003433240.130
regulation of mrna processingGO:005068430.105
ameboidal type cell migrationGO:00016671430.100
cellular macromolecule metabolic processGO:00442603910.086
leukocyte proliferationGO:007066110.078
response to carbohydrateGO:000974330.073
regulation of blood vessel sizeGO:005088020.070
protein import into nucleusGO:000660630.070
heart developmentGO:00075073130.070
sensory organ developmentGO:00074233930.069
eye developmentGO:00016542770.068
maintenance of epithelial cell apical basal polarityGO:004519950.068
retina development in camera type eyeGO:00600411460.065
response to hexoseGO:000974630.065
actin cytoskeleton organizationGO:0030036630.063
nitrogen compound metabolic processGO:00068073190.063
cytoskeleton organizationGO:0007010960.060
mononuclear cell proliferationGO:003294310.058
regulation of tube sizeGO:003515020.058
regulation of mrna catabolic processGO:006101330.056
nucleic acid templated transcriptionGO:00976591810.056
cell surface receptor signaling pathwayGO:00071663250.056
modification dependent protein catabolic processGO:001994130.055
nuclear migrationGO:000709730.055
actomyosin structure organizationGO:0031032530.053
organic substance biosynthetic processGO:19015762890.053
cellular component movementGO:00069283350.053
regulation of glucose transportGO:001082710.051
regulation of protein transportGO:005122330.050
multicellular organism growthGO:003526440.050
immune system processGO:00023762410.049
camera type eye developmentGO:00430102220.049
morphogenesis of an epitheliumGO:00020093330.049
protein localization to nucleusGO:003450430.049
positive regulation of catabolic processGO:000989640.048
response to nutrientGO:000758430.048
positive regulation of cellular catabolic processGO:003133130.048
nuclear importGO:005117030.048
medulla oblongata developmentGO:002155040.047
regulation of glucose importGO:004632410.046
protein importGO:001703830.045
rna 3 end processingGO:003112320.044
response to monosaccharideGO:003428430.044
positive regulation of transportGO:005105020.043
regulation of cell projection assemblyGO:006049140.043
stem cell proliferationGO:007208940.042
response to drugGO:004249330.042
neuroblast proliferationGO:000740520.041
regulation of cytokine productionGO:000181730.041
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.041
establishment of protein localization to organelleGO:007259440.040
regulation of intracellular protein transportGO:003315730.040
cellular component assemblyGO:00226071700.039
proteolysis involved in cellular protein catabolic processGO:005160330.039
regulation of wound healingGO:006104120.038
response to glucoseGO:000974930.038
regulation of nucleobase containing compound metabolic processGO:00192192500.037
single organism metabolic processGO:00447102170.037
positive regulation of cellular component biogenesisGO:004408930.037
regulation of filopodium assemblyGO:005148920.037
nucleocytoplasmic transportGO:000691340.037
vasculature developmentGO:00019442780.036
adherens junction maintenanceGO:003433420.036
regulation of cytoplasmic transportGO:190364940.036
muscle cell developmentGO:00550011150.036
regulation of cell substrate adhesionGO:001081010.036
system processGO:00030081850.036
maintenance of locationGO:005123540.035
regulation of establishment of protein localizationGO:007020140.035
embryonic heart tube developmentGO:00350501330.035
modification dependent macromolecule catabolic processGO:004363230.034
actin filament based processGO:0030029640.034
response to stressGO:00069502630.034
larval developmentGO:000216420.034
regulation of cell shapeGO:000836010.034
smooth muscle contractionGO:000693920.034
gene expressionGO:00104672520.034
heterocycle metabolic processGO:00464832900.034
cellular aromatic compound metabolic processGO:00067252950.034
macromolecule biosynthetic processGO:00090592270.033
positive regulation of glucose transportGO:001082810.033
regenerationGO:0031099910.033
regulation of signal transductionGO:00099662250.032
cellular protein catabolic processGO:004425740.032
myofibril assemblyGO:0030239480.032
regulation of macromolecule biosynthetic processGO:00105562250.032
heterocycle biosynthetic processGO:00181302150.032
single organism organelle organizationGO:19025891990.032
regulation of nucleocytoplasmic transportGO:004682220.032
regulation of myotube differentiationGO:001083020.032
biosynthetic processGO:00090582940.031
establishment or maintenance of bipolar cell polarityGO:0061245120.031
glucose importGO:004632320.030
autophagyGO:000691440.030
camera type eye morphogenesisGO:00485931080.029
cell matrix adhesionGO:000716040.029
positive regulation of secretion by cellGO:190353210.029
single organism nuclear importGO:190259330.029
regulation of protein catabolic processGO:004217610.029
transcription dna templatedGO:00063511810.029
actin polymerization or depolymerizationGO:000815420.029
dorsal motor nucleus of vagus nerve developmentGO:002174440.029
regulation of protein modification by small protein conjugation or removalGO:190332030.028
mrna catabolic processGO:000640260.028
lymphocyte proliferationGO:004665110.028
immune system developmentGO:00025201910.028
cell migration involved in sprouting angiogenesisGO:000204280.028
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.028
positive regulation of cytokine productionGO:000181920.028
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.028
regulation of protein localization to nucleusGO:190018020.028
signal transductionGO:00071654550.028
regulation of protein targetingGO:190353320.028
regulation of protein ubiquitinationGO:003139630.028
protein targeting to nucleusGO:004474430.027
regulation of i kappab kinase nf kappab signalingGO:004312240.027
regulation of multicellular organism growthGO:004001440.027
blood vessel morphogenesisGO:00485142160.027
positive regulation of cell substrate adhesionGO:001081110.027
cell junction maintenanceGO:003433120.027
regulation of cell migration involved in sprouting angiogenesisGO:009004930.027
cellular biosynthetic processGO:00442492860.027
cellular amino acid metabolic processGO:000652070.027
regulation of gene expressionGO:00104682650.027
sensory organ morphogenesisGO:00905962000.026
positive regulation of cell activationGO:005086710.026
positive regulation of macromolecule metabolic processGO:0010604930.026
digestive tract mesoderm developmentGO:000750210.026
i kappab kinase nf kappab signalingGO:000724940.026
regulation of nitrogen compound metabolic processGO:00511712510.026
maintenance of cell polarityGO:003001150.026
ubiquitin dependent protein catabolic processGO:000651130.025
rna biosynthetic processGO:00327741810.025
embryonic organ developmentGO:00485683810.025
tube morphogenesisGO:00352393490.024
organelle assemblyGO:00709251100.024
protein complex localizationGO:003150310.024
blood vessel developmentGO:00015682460.024
regulation of transcription dna templatedGO:00063552130.024
regulation of signalingGO:00230512350.024
somatic muscle developmentGO:000752540.024
positive regulation of cell cycleGO:004578730.024
nucleobase containing compound biosynthetic processGO:00346542050.024
cell cycle g2 m phase transitionGO:004483940.024
regulation of biosynthetic processGO:00098892500.024
eye morphogenesisGO:00485921440.024
rna metabolic processGO:00160702190.023
regulation of primary metabolic processGO:00800903110.023
carboxylic acid metabolic processGO:0019752220.023
localization of cellGO:00516742440.023
establishment or maintenance of apical basal cell polarityGO:0035088120.023
myotube differentiationGO:0014902450.023
negative regulation of apoptotic processGO:0043066550.023
g2 m transition of mitotic cell cycleGO:000008640.022
cell motilityGO:00488702440.022
embryo development ending in birth or egg hatchingGO:00097922710.022
negative regulation of signal transductionGO:0009968940.022
blood circulationGO:0008015870.022
angiogenesisGO:00015251580.022
specification of symmetryGO:00097992040.022
negative regulation of protein phosphorylationGO:000193340.022
nucleic acid metabolic processGO:00903042440.022
positive regulation of cytoskeleton organizationGO:005149530.022
single organism localizationGO:19025782250.022
positive regulation of cell adhesionGO:004578510.022
positive regulation of muscle cell differentiationGO:005114910.021
striated muscle cell differentiationGO:00511461290.021
regulation of rna biosynthetic processGO:20011412130.021
regulation of biological qualityGO:00650082630.021
sprouting angiogenesisGO:0002040530.021
organelle organizationGO:00069962270.021
cell projection organizationGO:00300302840.021
cell migrationGO:00164772370.021
organic cyclic compound metabolic processGO:19013603010.021
odontogenesis of dentin containing toothGO:004247510.021
mrna 3 end processingGO:003112420.021
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.021
positive regulation of secretionGO:005104710.020
circulatory system processGO:0003013870.020
convergent extensionGO:00600261180.020
nucleobase containing compound metabolic processGO:00061392740.020
response to hormoneGO:0009725480.020
regulation of apoptotic processGO:0042981980.020
response to external stimulusGO:00096052640.020
regulation of cellular macromolecule biosynthetic processGO:20001122220.020
regulation of cellular biosynthetic processGO:00313262450.020
determination of bilateral symmetryGO:00098552040.020
organonitrogen compound metabolic processGO:1901564740.020
chondrocyte developmentGO:000206340.020
positive regulation of glucose importGO:004632610.019
regulation of cell matrix adhesionGO:000195210.019
negative regulation of biological processGO:00485193040.019
aromatic compound biosynthetic processGO:00194382170.019
cellular component biogenesisGO:00440851780.019
organic acid metabolic processGO:0006082310.019
nuclear transportGO:005116940.018
digestive tract morphogenesisGO:00485462310.018
macromolecule catabolic processGO:0009057150.018
regulation of organ growthGO:004662030.018
histone h3 k4 methylationGO:005156820.018
response to abiotic stimulusGO:00096281220.018
oxoacid metabolic processGO:0043436310.018
cellular component maintenanceGO:004395430.018
protein modification processGO:00362111000.018
peptide transportGO:001583310.018
hematopoietic or lymphoid organ developmentGO:00485341910.017
cellular response to extracellular stimulusGO:003166820.017
cellular response to external stimulusGO:007149620.017
protein metabolic processGO:00195381830.017
muscle structure developmentGO:00610611960.017
retina morphogenesis in camera type eyeGO:0060042790.017
regionalizationGO:00030022740.017
meiotic nuclear divisionGO:000712640.017
regulation of wnt signaling pathwayGO:0030111530.017
macromolecular complex subunit organizationGO:0043933740.017
cellular nitrogen compound metabolic processGO:00346412900.017
central nervous system developmentGO:00074173870.017
response to chemicalGO:00422213200.017
synaptic growth at neuromuscular junctionGO:005112420.017
cellular component assembly involved in morphogenesisGO:00109271070.017
negative regulation of signalingGO:0023057960.017
cell deathGO:00082191210.017
dna templated transcription elongationGO:000635430.017
microtubule based processGO:0007017600.017
establishment of spindle localizationGO:0051293120.016
regulation of reproductive processGO:200024140.016
proteasomal protein catabolic processGO:001049820.016
regulation of response to stimulusGO:00485832690.016
regulation of protein import into nucleusGO:004230620.016
hemopoiesisGO:00300971830.016
determination of left right symmetryGO:00073681790.016
cell projection assemblyGO:0030031640.016
mrna metabolic processGO:0016071200.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
regulation of blood circulationGO:1903522320.016
head developmentGO:00603223030.016
negative regulation of protein kinase activityGO:000646940.016
organic cyclic compound biosynthetic processGO:19013622230.016
protein heterooligomerizationGO:005129110.016
epithelial tube morphogenesisGO:00605621480.016
deathGO:00162651210.016
regulation of skeletal muscle fiber developmentGO:004874220.016
cellular protein metabolic processGO:00442671290.016
regulation of cell motilityGO:2000145460.016
neural nucleus developmentGO:0048857150.015
regulation of multicellular organismal processGO:00512392770.015
protein secretionGO:000930610.015
mitochondrion organizationGO:000700540.015
regulation of blood coagulationGO:003019310.015
convergent extension involved in gastrulationGO:0060027710.015
regulation of cellular protein catabolic processGO:190336210.015
single organism cellular localizationGO:1902580460.015
cellular response to organic substanceGO:00713101050.015
phagocytosisGO:000690930.015
growthGO:00400071740.015
meiotic chromosome segregationGO:004513230.015
cell cell junction maintenanceGO:004521710.015
response to temperature stimulusGO:0009266150.015
mesoderm developmentGO:0007498880.015
lipid catabolic processGO:001604240.015
hindbrain developmentGO:0030902910.015
embryonic hemopoiesisGO:0035162530.015
regulation of muscle contractionGO:000693730.014
embryonic skeletal joint developmentGO:007249830.014
neuron differentiationGO:00301823530.014
digestive tract developmentGO:00485652650.014
regulation of cellular component movementGO:0051270550.014
positive regulation of nucleoside metabolic processGO:004597910.014
cell cycle g1 s phase transitionGO:004484310.014
regulation of cellular metabolic processGO:00313233200.014
phagocytosis engulfmentGO:000691110.014
wound healingGO:0042060900.014
spermatid developmentGO:000728620.014
negative regulation of programmed cell deathGO:0043069580.014
cellular component morphogenesisGO:00329893360.014
regulation of rho protein signal transductionGO:003502320.014
positive regulation of translationGO:004572710.014
cellular ketone metabolic processGO:0042180110.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
intracellular signal transductionGO:0035556850.013
small molecule metabolic processGO:0044281770.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
negative regulation of response to stimulusGO:00485851040.013
microtubule organizing center organizationGO:003102310.013
gtp metabolic processGO:004603940.013
cellular component disassemblyGO:002241110.013
regulation of metabolic processGO:00192223590.013
negative regulation of mapk cascadeGO:004340940.013
meiotic cell cycle processGO:190304630.013
heart morphogenesisGO:00030071560.013
rna processingGO:0006396250.013
protein polymerizationGO:005125840.013
glycoprotein metabolic processGO:0009100230.013
negative regulation of cell deathGO:0060548600.013
nucleoside monophosphate catabolic processGO:000912540.013
striated muscle cell developmentGO:00550021080.013
translational initiationGO:000641330.013
protein localization to plasma membraneGO:007265910.013
phosphatidylinositol 3 kinase signalingGO:001406520.013
ribonucleoprotein complex biogenesisGO:0022613130.013
negative regulation of kinase activityGO:003367340.013
amine metabolic processGO:000930820.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
regulation of inflammatory responseGO:005072720.013
cell migration involved in gastrulationGO:0042074790.013
response to endogenous stimulusGO:0009719830.012
brain developmentGO:00074202930.012
hemostasisGO:0007599130.012
cellular carbohydrate metabolic processGO:004426240.012
chordate embryonic developmentGO:00430092710.012
regulation of nucleoside metabolic processGO:000911820.012
gastrulationGO:00073692080.012
regulation of cell activationGO:005086510.012
gtp catabolic processGO:000618420.012
cellular macromolecule biosynthetic processGO:00346452240.012
negative regulation of cellular processGO:00485232830.012
regulation of epithelial cell proliferationGO:005067830.012
positive regulation of biological processGO:00485182530.012
negative regulation of reproductive processGO:200024230.012
sleepGO:003043110.012
cellular amine metabolic processGO:004410620.012
regulation of cell deathGO:00109411030.012
regulation of cellular amine metabolic processGO:003323800.012
protein complex disassemblyGO:004324110.012
b cell activationGO:004211320.012
synaptic target recognitionGO:000803910.012
membrane invaginationGO:001032410.012
establishment of organelle localizationGO:0051656450.012
negative regulation of synapse assemblyGO:005196420.012
neurotransmitter transportGO:000683620.012
skeletal system developmentGO:00015011810.012
guanosine containing compound metabolic processGO:190106840.012
skeletal muscle tissue developmentGO:0007519670.012
positive regulation of striated muscle cell differentiationGO:005115510.012
spermatid differentiationGO:004851520.012
regulation of hemostasisGO:190004610.012
regulation of rna metabolic processGO:00512522240.012
actin filament polymerizationGO:003004120.012
compound eye developmentGO:004874920.011
regulation of anatomical structure morphogenesisGO:00226031300.011
innervationGO:006038430.011
carbohydrate biosynthetic processGO:001605110.011
positive regulation of protein kinase b signalingGO:005189710.011
negative chemotaxisGO:005091910.011
regulation of skeletal muscle tissue developmentGO:004864140.011
positive regulation of muscle tissue developmentGO:190186310.011
lipid storageGO:001991510.011
somite developmentGO:0061053960.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
startle responseGO:000196440.011
heart loopingGO:0001947940.011
secondary metabolic processGO:001974830.011
nerve developmentGO:0021675450.011
single organism transportGO:00447652060.011
atp catabolic processGO:000620040.011
regulation of reactive oxygen species metabolic processGO:200037720.011
cell substrate junction assemblyGO:000704420.011
regulation of macromolecule metabolic processGO:00602553170.011
regulation of gtpase activityGO:004308720.011
cell part morphogenesisGO:00329902460.011
cellular protein modification processGO:00064641000.011
macromolecular complex disassemblyGO:003298410.011
transportGO:00068102200.011
cellular response to chemical stimulusGO:00708871570.011
regulation of actin filament based movementGO:190311510.011
regulation of mrna splicing via spliceosomeGO:004802430.011
determination of heart left right asymmetryGO:00613711170.011
digestive system developmentGO:00551232890.011
response to light stimulusGO:0009416460.011
positive regulation of nucleotide catabolic processGO:003081310.011
regulation of cell communicationGO:00106462320.011
muscle cell migrationGO:001481240.010
embryonic skeletal joint morphogenesisGO:006027230.010
mrna processingGO:0006397140.010
cellular response to hypoxiaGO:007145610.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
macromolecule modificationGO:00434121110.010
proteolysisGO:0006508380.010
regulation of anatomical structure sizeGO:0090066330.010
regulation of cellular ketone metabolic processGO:001056570.010
regulation of alternative mrna splicing via spliceosomeGO:000038110.010
guanosine containing compound catabolic processGO:190106920.010
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.010
apoptotic processGO:00069151160.010
tissue regenerationGO:0042246740.010
positive regulation of striated muscle tissue developmentGO:004584410.010
organelle localizationGO:0051640490.010
homeostatic processGO:00425921420.010
nuclear transcribed mrna catabolic processGO:000095640.010
positive regulation of cell matrix adhesionGO:000195410.010
positive regulation of cellular processGO:00485222010.010
developmental growthGO:00485891660.010
viral processGO:001603210.010
regulation of cardiac muscle contractionGO:005511720.010
post embryonic organ developmentGO:004856940.010
regulation of nucleotide catabolic processGO:003081120.010
embryonic skeletal system developmentGO:0048706970.010
ras protein signal transductionGO:000726570.010

vcl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
muscular diseaseDOID:008000000.021
musculoskeletal system diseaseDOID:1700.021
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013
myopathyDOID:42300.013
muscle tissue diseaseDOID:6600.013
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.012
nervous system diseaseDOID:86300.012
sensory system diseaseDOID:005015500.012