Danio rerio

56 known processes

vcp

valosin containing protein

(Aliases: wu:fd16d05,wu:fj63d11,CDC48)

vcp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.745
ubiquitin dependent protein catabolic processGO:000651130.742
larval developmentGO:000216420.728
Worm
modification dependent protein catabolic processGO:001994130.723
cellular component assemblyGO:00226071700.525
Human Mouse Rat
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.482
Human Yeast Rat Worm
response to stressGO:00069502630.467
Human Yeast Worm
modification dependent macromolecule catabolic processGO:004363230.455
dna templated transcription initiationGO:000635210.411
cellular protein catabolic processGO:004425740.406
cellular component morphogenesisGO:00329893360.377
proteolysis involved in cellular protein catabolic processGO:005160330.369
ribonucleoside monophosphate catabolic processGO:000915840.348
Yeast Rat Worm
regulation of biological qualityGO:00650082630.344
Yeast
positive regulation of cellular component biogenesisGO:004408930.280
Human
cellular protein complex assemblyGO:0043623190.266
nucleoside monophosphate catabolic processGO:000912540.266
Yeast Rat Worm
protein complex subunit organizationGO:0071822460.234
Human Yeast Rat
actin filament based processGO:0030029640.227
single organism organelle organizationGO:19025891990.211
Yeast
defense responseGO:0006952470.211
sensory organ developmentGO:00074233930.206
locomotionGO:00400113130.205
Worm
proteasomal protein catabolic processGO:001049820.204
Human Yeast Rat Worm
response to external biotic stimulusGO:0043207970.198
cytokinesisGO:000091030.194
neuron developmentGO:00486662620.185
purine ribonucleoside monophosphate catabolic processGO:000916940.178
Yeast Rat Worm
single organism localizationGO:19025782250.177
Human Yeast Rat
positive regulation of protein complex assemblyGO:003133420.158
Human
response to external stimulusGO:00096052640.151
Yeast
response to other organismGO:0051707970.143
protein complex assemblyGO:0006461300.140
Human Rat
purine nucleoside monophosphate catabolic processGO:000912840.136
Yeast Rat Worm
immune system processGO:00023762410.136
stem cell divisionGO:001714510.124
regulation of protein complex assemblyGO:004325430.119
Human
cellular macromolecular complex assemblyGO:0034622240.118
camera type eye developmentGO:00430102220.116
organelle assemblyGO:00709251100.114
cellular component biogenesisGO:00440851780.113
Human Mouse Rat
homeostatic processGO:00425921420.103
eye developmentGO:00016542770.101
response to bacteriumGO:0009617580.100
positive regulation of nuclease activityGO:003207510.094
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.092
embryo development ending in birth or egg hatchingGO:00097922710.091
Worm
regulation of metabolic processGO:00192223590.090
regulation of response to stimulusGO:00485832690.089
regulation of immune system processGO:0002682340.089
autophagyGO:000691440.089
Yeast
macromolecular complex assemblyGO:0065003350.088
Human Rat
guanosine containing compound catabolic processGO:190106920.088
programmed cell deathGO:00125011190.084
Mouse
response to abiotic stimulusGO:00096281220.083
small gtpase mediated signal transductionGO:000726480.083
actin cytoskeleton organizationGO:0030036630.082
cellular component maintenanceGO:004395430.082
ras protein signal transductionGO:000726570.078
negative regulation of biological processGO:00485193040.077
regulation of multicellular organismal developmentGO:20000262230.077
regulation of gene expressionGO:00104682650.073
pole plasm assemblyGO:000731540.072
meiotic cell cycle processGO:190304630.072
cellular response to chemical stimulusGO:00708871570.069
Yeast Worm
positive regulation of biological processGO:00485182530.069
Human Yeast Mouse Rat Worm
hepaticobiliary system developmentGO:0061008980.069
aromatic compound biosynthetic processGO:00194382170.066
Human
blood vessel developmentGO:00015682460.066
organic substance catabolic processGO:1901575280.064
cellular macromolecule metabolic processGO:00442603910.063
negative regulation of small gtpase mediated signal transductionGO:005105810.063
regulation of protein catabolic processGO:004217610.063
regulation of neural precursor cell proliferationGO:200017730.062
response to biotic stimulusGO:0009607970.062
mitochondrion organizationGO:000700540.061
neuron differentiationGO:00301823530.060
gene silencing by rnaGO:003104740.060
reproductionGO:0000003400.060
Worm
embryonic skeletal system morphogenesisGO:0048704930.060
immune responseGO:0006955280.059
cellular macromolecule catabolic processGO:0044265120.059
negative regulation of protein phosphorylationGO:000193340.059
cellular biosynthetic processGO:00442492860.059
Human
protein importGO:001703830.059
blood vessel morphogenesisGO:00485142160.058
vasculature developmentGO:00019442780.058
heterocycle biosynthetic processGO:00181302150.056
Human
rna biosynthetic processGO:00327741810.056
cytoskeleton dependent cytokinesisGO:006164030.055
nucleocytoplasmic transportGO:000691340.054
embryonic skeletal system developmentGO:0048706970.053
cell morphogenesisGO:00009022890.053
protein complex biogenesisGO:0070271300.053
Human Rat
cell motilityGO:00488702440.051
proteolysisGO:0006508380.050
regulation of nuclease activityGO:003206910.050
single organism nuclear importGO:190259330.050
regulation of epithelial cell proliferationGO:005067830.050
cell projection morphogenesisGO:00488582440.049
atp catabolic processGO:000620040.048
Yeast Rat Worm
embryonic organ developmentGO:00485683810.047
response to drugGO:004249330.047
post golgi vesicle mediated transportGO:000689210.046
fertilizationGO:000956630.046
negative regulation of cellular metabolic processGO:0031324770.046
signal transductionGO:00071654550.045
Worm
generation of neuronsGO:00486993850.044
positive regulation of cellular catabolic processGO:003133130.044
Human Rat
cell morphogenesis involved in differentiationGO:00009041950.044
heterocycle metabolic processGO:00464832900.044
Human Yeast Rat Worm
oocyte developmentGO:0048599140.044
cellular response to nutrient levelsGO:003166920.043
Yeast
positive regulation of response to stimulusGO:0048584800.043
positive regulation of cellular metabolic processGO:0031325940.043
Human Yeast Mouse Rat
small molecule metabolic processGO:0044281770.042
Yeast Rat Worm
muscle cell developmentGO:00550011150.042
cellular catabolic processGO:0044248270.042
macromolecular complex subunit organizationGO:0043933740.041
Human Yeast Rat
regulation of cellular metabolic processGO:00313233200.041
mitotic cell cycle processGO:1903047480.040
Yeast
skeletal system developmentGO:00015011810.040
cellular component disassemblyGO:002241110.040
Yeast
regulation of macromolecule metabolic processGO:00602553170.039
protein import into nucleusGO:000660630.039
organelle organizationGO:00069962270.038
Yeast Worm
phosphorus metabolic processGO:00067931090.038
Yeast Rat Worm
regulation of primary metabolic processGO:00800903110.037
neuroblast proliferationGO:000740520.037
ion homeostasisGO:0050801410.037
cell migrationGO:00164772370.037
regulation of response to stressGO:0080134360.037
establishment of localization in cellGO:0051649770.037
Human Yeast Rat
response to lipidGO:0033993600.037
regulation of cell communicationGO:00106462320.036
spindle assemblyGO:005122520.036
positive regulation of catabolic processGO:000989640.036
Human Rat
regulation of localizationGO:00328791040.036
Yeast
protein polymerizationGO:005125840.035
cellular transition metal ion homeostasisGO:004691630.035
protein targeting to nucleusGO:004474430.035
ribonucleotide metabolic processGO:0009259270.035
Yeast Rat Worm
embryonic cranial skeleton morphogenesisGO:0048701900.035
protein metabolic processGO:00195381830.035
single organism metabolic processGO:00447102170.035
Human Yeast Rat Worm
angiogenesisGO:00015251580.034
cellular aromatic compound metabolic processGO:00067252950.033
Human Yeast Rat Worm
maintenance of locationGO:005123540.033
Yeast
regulation of reproductive processGO:200024140.033
apoptotic process involved in morphogenesisGO:006056120.033
regulation of filopodium assemblyGO:005148920.033
golgi vesicle transportGO:004819330.033
Rat
regulation of stem cell proliferationGO:007209120.033
regulation of protein localization to nucleusGO:190018020.032
Yeast
regulation of cellular biosynthetic processGO:00313262450.032
cellular response to extracellular stimulusGO:003166820.032
Yeast
striated muscle cell developmentGO:00550021080.031
response to organic substanceGO:00100331530.031
Yeast Worm
rna metabolic processGO:00160702190.031
Yeast
cell deathGO:00082191210.031
Mouse
apoptotic process involved in developmentGO:190274220.031
macromolecular complex disassemblyGO:003298410.031
Yeast
regulation of establishment of protein localizationGO:007020140.031
cellular protein modification processGO:00064641000.031
spermatid developmentGO:000728620.031
regulation of synaptic plasticityGO:004816710.030
macromolecule biosynthetic processGO:00090592270.030
Human
positive regulation of translationGO:004572710.030
deathGO:00162651210.030
Mouse
positive regulation of gene expressionGO:0010628710.029
regulation of cellular macromolecule biosynthetic processGO:20001122220.029
synaptic growth at neuromuscular junctionGO:005112420.029
positive regulation of macromolecule metabolic processGO:0010604930.029
Human Yeast Mouse Rat
response to organic cyclic compoundGO:0014070510.029
phagocytosisGO:000690930.029
actomyosin structure organizationGO:0031032530.029
double strand break repairGO:000630230.029
Human
negative regulation of signalingGO:0023057960.029
positive regulation of metabolic processGO:00098931080.028
Human Yeast Mouse Rat
regulation of cell activationGO:005086510.028
negative regulation of multicellular organismal processGO:0051241690.028
innate immune responseGO:0045087130.028
response to antibioticGO:004667710.028
single organism transportGO:00447652060.027
Human Yeast Rat
cellular response to stressGO:0033554620.027
Human Yeast Worm
oocyte anterior posterior axis specificationGO:000731440.027
epithelial cell differentiationGO:00308551160.027
immune system developmentGO:00025201910.027
nucleic acid metabolic processGO:00903042440.027
Human Yeast
response to topologically incorrect proteinGO:003596620.026
Yeast Worm
post embryonic developmentGO:000979170.026
Worm
central nervous system developmentGO:00074173870.026
organic substance transportGO:0071702580.026
Human Yeast
stem cell proliferationGO:007208940.026
regulation of synaptic growth at neuromuscular junctionGO:000858210.026
regulation of bindingGO:005109830.026
protein n linked glycosylationGO:000648710.026
Human
establishment of localizationGO:00512342440.025
Human Yeast Rat
peptide metabolic processGO:000651810.025
cellular response to lipidGO:0071396390.025
regulation of macromolecule biosynthetic processGO:00105562250.025
embryonic organ morphogenesisGO:00485622740.025
gtp catabolic processGO:000618420.025
chordate embryonic developmentGO:00430092710.025
catabolic processGO:0009056320.025
cellular response to external stimulusGO:007149620.025
Yeast
negative regulation of gene expressionGO:0010629650.024
regulation of cytoplasmic transportGO:190364940.023
transportGO:00068102200.023
Human Yeast Rat
tor signalingGO:003192970.023
defense response to other organismGO:0098542330.023
negative regulation of metabolic processGO:0009892860.023
positive regulation of cellular processGO:00485222010.023
Human Yeast Mouse Rat
positive regulation of rna biosynthetic processGO:1902680570.023
microtubule cytoskeleton organizationGO:0000226330.023
Yeast
cell fate commitmentGO:0045165990.023
cellular response to dna damage stimulusGO:0006974240.023
Human
guanosine containing compound metabolic processGO:190106840.023
neuron projection morphogenesisGO:00488121610.023
tissue remodelingGO:004877140.023
organic cyclic compound biosynthetic processGO:19013622230.022
Human
transcription from rna polymerase ii promoterGO:0006366800.022
organonitrogen compound metabolic processGO:1901564740.022
Yeast Rat Worm
oocyte maturationGO:000155640.022
regulation of cellular protein catabolic processGO:190336210.022
intracellular signal transductionGO:0035556850.022
system processGO:00030081850.022
regulation of signalingGO:00230512350.022
regulation of synapse assemblyGO:005196330.022
positive regulation of signalingGO:0023056560.022
regulation of rna biosynthetic processGO:20011412130.022
cell cycleGO:0007049930.022
Yeast Worm
positive regulation of transportGO:005105020.022
gene expressionGO:00104672520.021
Mouse
cellular component assembly involved in morphogenesisGO:00109271070.021
positive regulation of cellular biosynthetic processGO:0031328680.021
nuclear importGO:005117030.021
regulation of nitrogen compound metabolic processGO:00511712510.021
single fertilizationGO:000733830.021
multi organism processGO:00517041340.021
nuclear transportGO:005116940.021
tube morphogenesisGO:00352393490.020
negative regulation of cell communicationGO:0010648960.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
gtp metabolic processGO:004603940.020
protein modification by small protein removalGO:007064610.020
Human
posttranscriptional gene silencing by rnaGO:003519430.020
neural precursor cell proliferationGO:0061351200.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.020
mitotic cell cycleGO:0000278640.020
Yeast
cytoplasm organizationGO:000702840.019
mononuclear cell proliferationGO:003294310.019
protein localization to nucleusGO:003450430.019
Yeast
head developmentGO:00603223030.019
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.019
cell cycle processGO:0022402530.019
Yeast
cellular macromolecule biosynthetic processGO:00346452240.019
Human
metal ion homeostasisGO:0055065260.019
negative regulation of response to stimulusGO:00485851040.019
response to hydrogen peroxideGO:004254230.019
regulation of signal transductionGO:00099662250.019
centrosome organizationGO:005129710.019
regulation of multicellular organismal processGO:00512392770.019
Worm
positive regulation of immune effector processGO:000269930.018
rrna catabolic processGO:001607510.018
Yeast
dna repairGO:000628160.018
Human
response to oxygen containing compoundGO:1901700550.018
regulation of mrna processingGO:005068430.018
positive regulation of rna metabolic processGO:0051254590.018
organic substance biosynthetic processGO:19015762890.018
Human
chondrocyte developmentGO:000206340.018
positive regulation of biosynthetic processGO:0009891680.018
digestive tract morphogenesisGO:00485462310.017
positive regulation of erk1 and erk2 cascadeGO:007037420.017
apoptotic processGO:00069151160.017
Mouse
protein dephosphorylationGO:000647030.017
nucleobase containing compound metabolic processGO:00061392740.017
Human Yeast Rat Worm
chemical homeostasisGO:0048878490.017
regenerationGO:0031099910.017
nucleic acid templated transcriptionGO:00976591810.017
spermatid differentiationGO:004851520.017
regulation of protein transportGO:005122330.017
cellular component movementGO:00069283350.017
intracellular transportGO:0046907320.017
Human Yeast Rat
regulation of endothelial cell proliferationGO:000193610.016
negative regulation of cellular catabolic processGO:003133030.016
amine metabolic processGO:000930820.016
positive regulation of secretion by cellGO:190353210.016
ear developmentGO:00435831270.016
establishment or maintenance of cell polarityGO:0007163290.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
regulation of calcium ion transportGO:005192420.016
synaptic transmissionGO:0007268350.016
regulation of inflammatory responseGO:005072720.015
centrosome cycleGO:000709810.015
purine ribonucleotide metabolic processGO:0009150270.015
Yeast Rat Worm
glycosyl compound metabolic processGO:1901657110.015
Yeast Rat Worm
transmembrane transportGO:00550851200.015
carbohydrate derivative metabolic processGO:1901135610.015
Human Yeast Rat Worm
regulation of dna catabolic processGO:190362410.015
establishment of protein localization to organelleGO:007259440.015
cell activationGO:0001775160.015
negative regulation of defense responseGO:003134820.015
response to hormoneGO:0009725480.015
macromolecule catabolic processGO:0009057150.015
heart developmentGO:00075073130.015
negative regulation of macromolecule metabolic processGO:0010605760.015
negative regulation of cytoplasmic transportGO:190365020.015
dorsal ventral pattern formationGO:00099531250.015
regulation of cytokine productionGO:000181730.015
myofibril assemblyGO:0030239480.015
negative regulation of apoptotic processGO:0043066550.015
positive regulation of neuron deathGO:190121610.015
regulation of protein metabolic processGO:0051246560.015
regulation of heart growthGO:006042020.015
regulation of protein bindingGO:004339330.014
protein modification processGO:00362111000.014
leukocyte homeostasisGO:000177620.014
regulation of autophagyGO:001050630.014
negative regulation of programmed cell deathGO:0043069580.014
cell divisionGO:0051301200.014
cell junction maintenanceGO:003433120.014
muscle organ developmentGO:00075171010.014
negative regulation of cellular processGO:00485232830.014
actin polymerization or depolymerizationGO:000815420.014
retina development in camera type eyeGO:00600411460.014
regulation of synapse organizationGO:005080730.014
carboxylic acid metabolic processGO:0019752220.014
mesenchyme developmentGO:00604851270.014
positive regulation of macromolecule biosynthetic processGO:0010557590.014
regulation of intracellular protein transportGO:003315730.014
response to endogenous stimulusGO:0009719830.013
transcription dna templatedGO:00063511810.013
regulation of purine nucleotide catabolic processGO:003312120.013
regulation of proteolysisGO:0030162240.013
dna templated transcription elongationGO:000635430.013
female gamete generationGO:0007292140.013
eye morphogenesisGO:00485921440.013
cytoskeleton organizationGO:0007010960.013
Yeast
nitrogen compound metabolic processGO:00068073190.013
Human Yeast Rat Worm
microtubule organizing center organizationGO:003102310.013
negative regulation of immune responseGO:005077720.013
wound healingGO:0042060900.013
ribose phosphate metabolic processGO:0019693270.013
Yeast Rat Worm
cell projection organizationGO:00300302840.013
cellular amine metabolic processGO:004410620.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
regulation of transcription from rna polymerase ii promoterGO:00063571140.013
positive regulation of transcription dna templatedGO:0045893570.013
gastrulationGO:00073692080.013
regulation of hematopoietic progenitor cell differentiationGO:190153210.013
meiotic spindle organizationGO:000021210.013
i kappab kinase nf kappab signalingGO:000724940.013
positive regulation of cytoskeleton organizationGO:005149530.013
regulation of nucleoside metabolic processGO:000911820.013
negative regulation of chromosome organizationGO:200125110.013
mitotic nuclear divisionGO:0007067180.012
Yeast
response to chemicalGO:00422213200.012
Yeast Worm
regulation of rna metabolic processGO:00512522240.012
localization of cellGO:00516742440.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
neuron projection developmentGO:00311751800.012
cellular response to organic cyclic compoundGO:0071407380.012
regulation of cellular amine metabolic processGO:003323800.012
multicellular organism growthGO:003526440.012
Worm
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
cell surface receptor signaling pathwayGO:00071663250.012
regulation of circadian rhythmGO:004275240.012
muscle structure developmentGO:00610611960.012
cellular nitrogen compound metabolic processGO:00346412900.012
Human Yeast Rat Worm
positive regulation of cell activationGO:005086710.012
peptidyl serine phosphorylationGO:001810510.012
regulation of wound healingGO:006104120.012
purine ribonucleoside triphosphate catabolic processGO:000920760.012
Yeast Rat Worm
muscle cell differentiationGO:00426921390.012
response to monosaccharideGO:003428430.012
response to carbohydrateGO:000974330.012
somatic muscle developmentGO:000752540.012
cellular amide metabolic processGO:004360340.012
single organism cellular localizationGO:1902580460.012
single organism intracellular transportGO:1902582250.012
Human Yeast Rat
digestive system developmentGO:00551232890.012
peptide transportGO:001583310.012
response to woundingGO:00096111160.012
protein localization to membraneGO:007265790.011
oogenesisGO:0048477140.011
extrinsic apoptotic signaling pathwayGO:009719130.011
iron ion homeostasisGO:005507240.011
negative regulation of neural precursor cell proliferationGO:200017810.011
regulation of defense responseGO:0031347140.011
zinc ion homeostasisGO:005506910.011
cellular homeostasisGO:0019725260.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
purine ribonucleoside metabolic processGO:0046128100.011
Yeast Rat Worm
cellular response to molecule of bacterial originGO:007121930.011
cartilage developmentGO:0051216960.011
positive regulation of dna metabolic processGO:005105410.011
chromatin organizationGO:0006325220.011
Yeast
regulation of immune responseGO:0050776140.011
response to temperature stimulusGO:0009266150.011
regulation of biosynthetic processGO:00098892500.011
positive regulation of protein metabolic processGO:0051247230.011
Human Yeast Mouse Rat
biosynthetic processGO:00090582940.011
Human
positive regulation of innate immune responseGO:004508980.011
phosphate containing compound metabolic processGO:00067961080.011
Yeast Rat Worm
maternal determination of anterior posterior axis embryoGO:000835840.011
nucleoside catabolic processGO:000916470.011
Yeast Rat Worm
positive regulation of apoptotic signaling pathwayGO:200123510.011
negative regulation of leukocyte differentiationGO:190210610.011
striated muscle cell differentiationGO:00511461290.011
regulation of apoptotic processGO:0042981980.011
Mouse
cellular protein metabolic processGO:00442671290.011
response to nitrogen compoundGO:1901698190.011
sister chromatid segregationGO:000081960.010
Yeast
leukocyte proliferationGO:007066110.010
cell type specific apoptotic processGO:0097285220.010
response to hexoseGO:000974630.010
growthGO:00400071740.010
Worm
macroautophagyGO:001623610.010
Yeast
positive regulation of cell cycleGO:004578730.010
positive regulation of wound healingGO:009030310.010
meiotic chromosome segregationGO:004513230.010
hemopoiesisGO:00300971830.010
cellular response to organic substanceGO:00713101050.010
Yeast Worm
positive regulation of protein polymerizationGO:003227320.010
negative regulation of multi organism processGO:004390130.010
regulation of oocyte developmentGO:006028130.010
determination of bilateral symmetryGO:00098552040.010
cellular response to starvationGO:000926710.010
Yeast
germ line stem cell maintenanceGO:003071820.010
mesenchymal cell differentiationGO:0048762870.010
regulation of molecular functionGO:0065009700.010
Human Yeast Mouse
kidney developmentGO:0001822920.010
cellular response to prostaglandin stimulusGO:007137930.010

vcp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.088
Human
central nervous system diseaseDOID:33100.036
Human
neurodegenerative diseaseDOID:128900.036
Human
nervous system diseaseDOID:86300.036
Human
tauopathyDOID:68000.036