Danio rerio

0 known processes

ppme1

protein phosphatase methylesterase 1

(Aliases: fk72d03,zgc:56239,wu:fk72d03)

ppme1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.182
Worm
agingGO:000756820.168
Worm
establishment of localizationGO:00512342440.160
cellular nitrogen compound metabolic processGO:00346412900.126
organonitrogen compound metabolic processGO:1901564740.120
single organism localizationGO:19025782250.107
organic cyclic compound metabolic processGO:19013603010.107
single organism organelle organizationGO:19025891990.106
transportGO:00068102200.098
nucleoside phosphate metabolic processGO:0006753280.092
centrosome organizationGO:005129710.088
microtubule organizing center organizationGO:003102310.086
signal transductionGO:00071654550.084
centrosome cycleGO:000709810.082
purine nucleoside monophosphate catabolic processGO:000912840.082
single fertilizationGO:000733830.081
microtubule based processGO:0007017600.081
cytokinesisGO:000091030.080
gtp catabolic processGO:000618420.080
regulation of establishment of protein localizationGO:007020140.074
single organism metabolic processGO:00447102170.072
cellular carbohydrate metabolic processGO:004426240.072
nucleobase containing compound metabolic processGO:00061392740.068
nitrogen compound metabolic processGO:00068073190.068
heterocycle metabolic processGO:00464832900.064
nucleobase containing small molecule metabolic processGO:0055086320.064
atp catabolic processGO:000620040.064
cellular aromatic compound metabolic processGO:00067252950.061
membrane fusionGO:006102520.060
purine ribonucleoside monophosphate catabolic processGO:000916940.060
secondary metabolic processGO:001974830.060
neuron differentiationGO:00301823530.060
nucleoside monophosphate catabolic processGO:000912540.058
regulation of protein transportGO:005122330.058
embryo development ending in birth or egg hatchingGO:00097922710.057
Worm
positive regulation of purine nucleotide catabolic processGO:003312310.056
ribonucleoside monophosphate catabolic processGO:000915840.056
pronuclear migrationGO:003504610.056
regulation of nucleoside metabolic processGO:000911820.053
positive regulation of cellular catabolic processGO:003133130.053
fertilizationGO:000956630.053
guanosine containing compound metabolic processGO:190106840.052
organophosphate metabolic processGO:0019637370.052
phagocytosisGO:000690930.048
single organism transportGO:00447652060.047
regulation of purine nucleotide catabolic processGO:003312120.047
cognitionGO:005089010.046
phagocytosis engulfmentGO:000691110.046
organelle fusionGO:004828430.045
pole plasm assemblyGO:000731540.044
maintenance of locationGO:005123540.043
regulation of cell communicationGO:00106462320.043
establishment of protein localization to organelleGO:007259440.042
multicellular organism growthGO:003526440.042
organelle organizationGO:00069962270.042
gtp metabolic processGO:004603940.042
regulation of protein ubiquitinationGO:003139630.042
cytoskeleton dependent cytokinesisGO:006164030.042
regulation of protein targetingGO:190353320.041
regulation of nucleobase containing compound metabolic processGO:00192192500.041
positive regulation of cell cycleGO:004578730.041
embryonic organ developmentGO:00485683810.041
purine nucleotide metabolic processGO:0006163270.041
positive regulation of biological processGO:00485182530.040
protein metabolic processGO:00195381830.040
guanosine containing compound catabolic processGO:190106920.040
small molecule metabolic processGO:0044281770.040
mitotic cell cycleGO:0000278640.039
establishment of synaptic vesicle localizationGO:009748010.039
mitochondrion organizationGO:000700540.039
locomotionGO:00400113130.039
regulation of carbohydrate metabolic processGO:000610940.039
positive regulation of catabolic processGO:000989640.038
locomotor rhythmGO:004547530.038
response to abiotic stimulusGO:00096281220.038
lateral inhibitionGO:004633110.038
cellular component morphogenesisGO:00329893360.038
regulation of cellular carbohydrate metabolic processGO:001067540.038
regulation of metabolic processGO:00192223590.037
meiotic cell cycle processGO:190304630.037
establishment of organelle localizationGO:0051656450.037
regulation of signalingGO:00230512350.036
regulation of nucleotide catabolic processGO:003081120.036
cellular macromolecule metabolic processGO:00442603910.036
negative regulation of biological processGO:00485193040.036
tube morphogenesisGO:00352393490.035
regulation of cell deathGO:00109411030.035
regulation of protein complex assemblyGO:004325430.034
nuclear migrationGO:000709730.034
cellular protein catabolic processGO:004425740.034
cellular biosynthetic processGO:00442492860.034
positive regulation of cellular processGO:00485222010.033
nucleotide metabolic processGO:0009117280.033
cell part morphogenesisGO:00329902460.033
neurological system processGO:0050877620.033
female sex differentiationGO:004666040.033
phosphorus metabolic processGO:00067931090.033
protein localization to plasma membraneGO:007265910.032
mitotic nuclear divisionGO:0007067180.032
synaptic vesicle transportGO:004848910.032
cell deathGO:00082191210.032
mitotic dna integrity checkpointGO:004477440.032
compound eye developmentGO:004874920.031
single organism membrane fusionGO:004480120.031
cellular response to starvationGO:000926710.031
positive regulation of nucleoside metabolic processGO:004597910.031
regulation of intracellular protein transportGO:003315730.031
microtubule cytoskeleton organizationGO:0000226330.031
regulation of response to stimulusGO:00485832690.031
regulation of programmed cell deathGO:00430671010.030
cellular response to external stimulusGO:007149620.030
positive regulation of gtp catabolic processGO:003312610.030
positive regulation of gtpase activityGO:004354710.030
vasculature developmentGO:00019442780.030
single organism nuclear importGO:190259330.029
centrosome duplicationGO:005129810.029
system processGO:00030081850.029
positive regulation of transportGO:005105020.029
regionalizationGO:00030022740.029
positive regulation of nucleotide catabolic processGO:003081310.028
stem cell maintenanceGO:001982740.028
oocyte anterior posterior axis specificationGO:000731440.028
organelle localizationGO:0051640490.028
programmed cell deathGO:00125011190.028
meiosis iGO:000712710.028
cellular component biogenesisGO:00440851780.027
nuclear importGO:005117030.027
regulation of primary metabolic processGO:00800903110.027
proteolysis involved in cellular protein catabolic processGO:005160330.027
regulation of nitrogen compound metabolic processGO:00511712510.027
cell surface receptor signaling pathwayGO:00071663250.027
regulation of multicellular organism growthGO:004001440.027
sensory organ developmentGO:00074233930.026
negative regulation of mapk cascadeGO:004340940.026
mitotic cell cycle embryonicGO:004544820.026
regulation of signal transductionGO:00099662250.026
purine ribonucleotide metabolic processGO:0009150270.026
regulation of chromosome segregationGO:005198310.025
phosphate containing compound metabolic processGO:00067961080.025
synaptic vesicle localizationGO:009747910.025
sister chromatid segregationGO:000081960.025
microtubule based movementGO:0007018330.025
meiotic nuclear divisionGO:000712640.024
protein acetylationGO:000647320.024
cellular component movementGO:00069283350.024
spermatid developmentGO:000728620.024
macromolecule modificationGO:00434121110.024
oxoacid metabolic processGO:0043436310.024
lipid storageGO:001991510.024
positive regulation of secretionGO:005104710.024
cellular protein modification processGO:00064641000.023
regulation of gtp catabolic processGO:003312420.023
cell agingGO:000756920.023
cellular nitrogen compound biosynthetic processGO:00442712180.023
cellular response to nutrient levelsGO:003166920.023
stem cell divisionGO:001714510.023
protein dephosphorylationGO:000647030.023
establishment of localization in cellGO:0051649770.023
cellular response to extracellular stimulusGO:003166820.023
adult behaviorGO:003053420.023
cellular amino acid metabolic processGO:000652070.023
negative regulation of protein serine threonine kinase activityGO:007190120.023
regulation of protein import into nucleusGO:004230620.022
small gtpase mediated signal transductionGO:000726480.022
amine metabolic processGO:000930820.022
regulation of meiotic cell cycleGO:005144510.022
extrinsic apoptotic signaling pathwayGO:009719130.022
positive regulation of secretion by cellGO:190353210.022
stem cell proliferationGO:007208940.022
generation of neuronsGO:00486993850.022
biosynthetic processGO:00090582940.022
establishment or maintenance of cell polarityGO:0007163290.022
cellular protein metabolic processGO:00442671290.022
organic cyclic compound biosynthetic processGO:19013622230.022
protein polymerizationGO:005125840.022
carboxylic acid metabolic processGO:0019752220.022
spermatid differentiationGO:004851520.022
digestive system developmentGO:00551232890.021
regulation of cellular ketone metabolic processGO:001056570.021
embryonic organ morphogenesisGO:00485622740.021
protein localization to nucleusGO:003450430.021
cilium morphogenesisGO:0060271850.021
mitotic cytokinesisGO:000028130.021
organic acid metabolic processGO:0006082310.021
membrane invaginationGO:001032410.021
cellular ketone metabolic processGO:0042180110.021
regulation of oocyte developmentGO:006028130.021
modification dependent macromolecule catabolic processGO:004363230.021
signal transduction in absence of ligandGO:003803410.021
regulation of reproductive processGO:200024140.021
regulation of protein modification by small protein conjugation or removalGO:190332030.020
response to uvGO:000941130.020
regulation of macromolecule metabolic processGO:00602553170.020
regulation of cell cycleGO:0051726520.020
cell cycle arrestGO:000705010.020
apoptotic processGO:00069151160.020
gastrulationGO:00073692080.020
regulation of gtpase activityGO:004308720.020
negative regulation of protein transportGO:005122430.020
cytoskeleton organizationGO:0007010960.020
exocytosisGO:000688710.020
regulation of cellular amino acid metabolic processGO:000652100.020
cell cycle g1 s phase transitionGO:004484310.020
regulation of cellular biosynthetic processGO:00313262450.020
cellular localizationGO:0051641970.020
response to stressGO:00069502630.020
cellular pigmentationGO:0033059300.019
regulation of sodium ion transportGO:000202820.019
negative regulation of kinase activityGO:003367340.019
intracellular mrna localizationGO:000829810.019
proteasomal protein catabolic processGO:001049820.019
cell motilityGO:00488702440.019
regulation of protein metabolic processGO:0051246560.019
protein import into nucleusGO:000660630.019
regulation of protein localization to nucleusGO:190018020.019
negative regulation of metabolic processGO:0009892860.019
muscle structure developmentGO:00610611960.019
central nervous system developmentGO:00074173870.019
digestive tract developmentGO:00485652650.019
single organism biosynthetic processGO:0044711710.019
negative regulation of nucleocytoplasmic transportGO:004682320.018
oxidation reduction processGO:0055114410.018
ubiquitin dependent protein catabolic processGO:000651130.018
regulation of cellular amine metabolic processGO:003323800.018
erk1 and erk2 cascadeGO:007037140.018
apoptotic process involved in developmentGO:190274220.018
regulation of wound healingGO:006104120.018
protein importGO:001703830.018
cell projection morphogenesisGO:00488582440.018
organelle assemblyGO:00709251100.018
cytoplasm organizationGO:000702840.018
kupffer s vesicle developmentGO:0070121500.018
cellular component assemblyGO:00226071700.018
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.018
protein targeting to nucleusGO:004474430.018
cellular amine metabolic processGO:004410620.017
meiotic chromosome segregationGO:004513230.017
urogenital system developmentGO:0001655970.017
response to radiationGO:0009314510.017
negative regulation of map kinase activityGO:004340720.017
ribose phosphate metabolic processGO:0019693270.017
regulation of protein catabolic processGO:004217610.017
protein modification by small protein removalGO:007064610.017
cell substrate adhesionGO:003158940.017
nuclear transportGO:005116940.017
positive regulation of cellular component biogenesisGO:004408930.017
regulation of cellular metabolic processGO:00313233200.017
regulation of cell shapeGO:000836010.017
axonogenesisGO:00074091520.017
cytokinetic processGO:003250620.017
protein stabilizationGO:005082120.017
cell morphogenesis involved in neuron differentiationGO:00486671630.017
kidney developmentGO:0001822920.017
pigmentationGO:0043473850.016
adherens junction organizationGO:003433240.016
lipid catabolic processGO:001604240.016
homeostatic processGO:00425921420.016
cell cycle processGO:0022402530.016
regulation of synapse organizationGO:005080730.016
negative regulation of intracellular transportGO:003238730.016
cellular monovalent inorganic cation homeostasisGO:003000420.016
maternal determination of anterior posterior axis embryoGO:000835840.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
deathGO:00162651210.016
purine containing compound metabolic processGO:0072521290.016
developmental programmed cell deathGO:001062340.016
cell migrationGO:00164772370.016
blood vessel developmentGO:00015682460.016
regulation of phosphorus metabolic processGO:0051174430.016
cell morphogenesisGO:00009022890.016
neuron projection morphogenesisGO:00488121610.016
blood vessel morphogenesisGO:00485142160.016
heart developmentGO:00075073130.016
atp synthesis coupled electron transportGO:004277310.016
intracellular signal transductionGO:0035556850.015
regulation of epithelial cell proliferationGO:005067830.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
regulation of synapse assemblyGO:005196330.015
immune system processGO:00023762410.015
regulation of mitochondrion organizationGO:001082110.015
regulation of metal ion transportGO:001095940.015
regulation of catalytic activityGO:0050790550.015
germ line stem cell maintenanceGO:003071820.015
protein secretionGO:000930610.015
renal system developmentGO:0072001940.015
organic substance biosynthetic processGO:19015762890.015
striated muscle cell differentiationGO:00511461290.015
brain developmentGO:00074202930.015
development of primary female sexual characteristicsGO:004654540.015
positive regulation of canonical wnt signaling pathwayGO:009026340.015
regulation of nucleocytoplasmic transportGO:004682220.015
nucleic acid metabolic processGO:00903042440.015
eye developmentGO:00016542770.015
endosomal transportGO:001619720.015
ribonucleotide metabolic processGO:0009259270.015
nucleocytoplasmic transportGO:000691340.014
regulation of bindingGO:005109830.014
negative regulation of protein kinase activityGO:000646940.014
specification of axis polarityGO:006500140.014
sensory organ morphogenesisGO:00905962000.014
regulation of developmental processGO:00507932470.014
negative regulation of catabolic processGO:000989530.014
modification dependent protein catabolic processGO:001994130.014
carbohydrate biosynthetic processGO:001605110.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
response to nutrientGO:000758430.014
mitotic cell cycle processGO:1903047480.014
negative regulation of cytoplasmic transportGO:190365020.014
mitochondrial atp synthesis coupled electron transportGO:004277510.014
spindle assemblyGO:005122520.014
negative regulation of reproductive processGO:200024230.014
regulation of cell substrate adhesionGO:001081010.014
protein acylationGO:004354330.014
positive regulation of cell deathGO:0010942290.014
rna modificationGO:000945120.014
cell cycleGO:0007049930.014
negative regulation of protein complex assemblyGO:003133310.014
negative regulation of nuclear divisionGO:005178430.014
cellular component assembly involved in morphogenesisGO:00109271070.014
inner ear developmentGO:00488391260.014
gene expressionGO:00104672520.014
cell fate commitmentGO:0045165990.014
ameboidal type cell migrationGO:00016671430.014
regulation of rna biosynthetic processGO:20011412130.014
behaviorGO:0007610740.014
regulation of cell activationGO:005086510.014
negative regulation of cellular processGO:00485232830.014
regulation of erk1 and erk2 cascadeGO:007037240.014
g1 s transition of mitotic cell cycleGO:000008210.014
regulation of biological qualityGO:00650082630.014
neuromuscular synaptic transmissionGO:000727420.014
g protein coupled receptor signaling pathwayGO:0007186740.014
cell migration involved in gastrulationGO:0042074790.014
regulation of phosphate metabolic processGO:0019220430.014
cell cycle g2 m phase transitionGO:004483940.014
localization of cellGO:00516742440.014
positive regulation of cellular amine metabolic processGO:003324000.013
cortical cytoskeleton organizationGO:003086510.013
carbohydrate derivative metabolic processGO:1901135610.013
carbohydrate homeostasisGO:003350010.013
endosome to lysosome transportGO:000833310.013
peptidyl serine phosphorylationGO:001810510.013
positive regulation of cell divisionGO:005178120.013
negative regulation of protein import into nucleusGO:004230820.013
positive regulation of programmed cell deathGO:0043068290.013
chromosome organizationGO:0051276310.013
digestive tract morphogenesisGO:00485462310.013
translational initiationGO:000641330.013
regulation of cytoplasmic transportGO:190364940.013
establishment of protein localization to vacuoleGO:007266610.013
organic substance transportGO:0071702580.013
negative regulation of multicellular organismal processGO:0051241690.013
negative regulation of protein localization to nucleusGO:190018120.013
negative regulation of cellular component organizationGO:0051129160.013
regulation of dendrite developmentGO:005077330.013
hormone biosynthetic processGO:004244630.013
peptidyl lysine acetylationGO:001839420.013
axis specificationGO:0009798430.013
thermosensory behaviorGO:004004010.013
regulation of biosynthetic processGO:00098892500.013
sex determinationGO:000753010.013
regulation of transmembrane transporter activityGO:002289820.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
negative regulation of cellular catabolic processGO:003133030.012
positive regulation of hydrolase activityGO:0051345130.012
pronephros developmentGO:0048793690.012
regulation of localizationGO:00328791040.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
positive regulation of small gtpase mediated signal transductionGO:005105710.012
phagosome maturationGO:009038210.012
rna metabolic processGO:00160702190.012
microtubule cytoskeleton organization involved in mitosisGO:190285010.012
macroautophagyGO:001623610.012
negative regulation of cellular metabolic processGO:0031324770.012
g2 m transition of mitotic cell cycleGO:000008640.012
cation transportGO:0006812810.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
negative regulation of small gtpase mediated signal transductionGO:005105810.012
hepaticobiliary system developmentGO:0061008980.012
vacuolar transportGO:000703420.012
anterior posterior pattern specificationGO:00099521520.012
response to external stimulusGO:00096052640.012
axon cargo transportGO:000808820.012
regulation of dna templated transcription in response to stressGO:004362000.012
negative regulation of synapse assemblyGO:005196420.012
regulation of exocytosisGO:001715710.012
positive regulation of purine nucleotide metabolic processGO:190054490.012
regulation of protein localization to plasma membraneGO:190307610.012
regulation of apoptotic processGO:0042981980.012
negative regulation of nitrogen compound metabolic processGO:0051172590.011
heterocycle biosynthetic processGO:00181302150.011
signal transduction by p53 class mediatorGO:0072331130.011
vesicle localizationGO:0051648270.011
cilium organizationGO:0044782710.011
circulatory system processGO:0003013870.011
cellular amide metabolic processGO:004360340.011
syncytium formationGO:0006949120.011
vesicle mediated transportGO:0016192220.011
actin filament polymerizationGO:003004120.011
positive regulation of macromolecule metabolic processGO:0010604930.011
neuroblast proliferationGO:000740520.011
regulation of circadian rhythmGO:004275240.011
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.011
multicellular organismal response to stressGO:003355520.011
synaptic growth at neuromuscular junctionGO:005112420.011
response to drugGO:004249330.011
negative regulation of response to stimulusGO:00485851040.011
autophagyGO:000691440.011
actin polymerization or depolymerizationGO:000815420.011
macromolecular complex subunit organizationGO:0043933740.011
positive regulation of stem cell proliferationGO:200064810.011
multi organism processGO:00517041340.011
reactive oxygen species metabolic processGO:007259360.011
oocyte constructionGO:000730850.011
axon developmentGO:00615641660.011
liver developmentGO:0001889960.011
developmental growthGO:00485891660.011
regulation of neurotransmitter transportGO:005158810.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
energy reserve metabolic processGO:000611220.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
dorsal ventral pattern formationGO:00099531250.011
rna localizationGO:000640340.011
regulation of ras gtpase activityGO:003231820.011
positive regulation of protein complex assemblyGO:003133420.011
negative regulation of intracellular protein transportGO:009031730.011
glucose homeostasisGO:004259310.011
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.011
reproductionGO:0000003400.011
Worm
olfactory lobe developmentGO:002198840.011
macromolecule biosynthetic processGO:00090592270.011
ovulation cycleGO:004269820.011
internal protein amino acid acetylationGO:000647520.011
alcohol biosynthetic processGO:004616520.011
negative regulation of chromosome organizationGO:200125110.011
positive regulation of dna metabolic processGO:005105410.011
chordate embryonic developmentGO:00430092710.011
head developmentGO:00603223030.011
spindle assembly involved in mitosisGO:009030710.011
organelle fissionGO:0048285230.011
peptide transportGO:001583310.011
organism emergence from protective structureGO:007168440.011
positive regulation of metabolic processGO:00098931080.011
regulation of cellular protein catabolic processGO:190336210.011
negative regulation of multi organism processGO:004390130.010
transmembrane transportGO:00550851200.010
apoptotic process involved in morphogenesisGO:006056120.010
circadian sleep wake cycle processGO:002241020.010
internal peptidyl lysine acetylationGO:001839320.010
pigment granule localizationGO:0051875250.010
regulation of synaptic plasticityGO:004816710.010
macromolecular complex assemblyGO:0065003350.010
multicellular organismal metabolic processGO:004423620.010
positive regulation of chromosome organizationGO:200125210.010
regulation of transcription dna templatedGO:00063552130.010
purine ribonucleoside triphosphate metabolic processGO:000920590.010
purine ribonucleotide catabolic processGO:000915460.010
neuron developmentGO:00486662620.010
negative regulation of protein phosphorylationGO:000193340.010
hatchingGO:003518840.010
female gonad developmentGO:000858540.010
regulation of cytokine productionGO:000181730.010
regulation of alternative mrna splicing via spliceosomeGO:000038110.010
histone modificationGO:0016570200.010

ppme1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.026
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.014
organ system cancerDOID:005068600.013
musculoskeletal system diseaseDOID:1700.011
sensory system diseaseDOID:005015500.011
disease of metabolismDOID:001466700.010