Danio rerio

74 known processes

diaph2

diaphanous homolog 2 (Drosophila)

(Aliases: sb:eu1025,si:dkeyp-11a1.1,dia2)

diaph2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of multicellular organismal developmentGO:20000262230.465
cellular carbohydrate metabolic processGO:004426240.224
positive regulation of transportGO:005105020.222
cell projection morphogenesisGO:00488582440.209
sensory perception of chemical stimulusGO:000760630.196
regulation of multicellular organism growthGO:004001440.149
cell morphogenesisGO:00009022890.147
regulation of cell differentiationGO:00455951420.138
positive regulation of cell differentiationGO:0045597300.135
camp biosynthetic processGO:0006171110.127
nitrogen compound metabolic processGO:00068073190.125
regulation of cell developmentGO:00602841000.124
striated muscle cell developmentGO:00550021080.122
regulation of cell shapeGO:000836010.121
regulation of developmental processGO:00507932470.118
neuron differentiationGO:00301823530.111
phagocytosisGO:000690930.111
signal transductionGO:00071654550.109
regulation of synapse organizationGO:005080730.105
camp metabolic processGO:0046058110.098
regulation of multicellular organismal processGO:00512392770.094
organonitrogen compound biosynthetic processGO:1901566470.091
neuron projection morphogenesisGO:00488121610.091
positive regulation of neuron projection developmentGO:001097690.089
muscle cell developmentGO:00550011150.088
cyclic nucleotide biosynthetic processGO:0009190180.086
phosphorus metabolic processGO:00067931090.085
digestive tract developmentGO:00485652650.079
cellular macromolecule metabolic processGO:00442603910.078
chemosensory behaviorGO:000763510.078
multicellular organism growthGO:003526440.077
apoptotic processGO:00069151160.077
positive regulation of multicellular organismal processGO:0051240520.076
cellular aromatic compound metabolic processGO:00067252950.075
regulation of signal transductionGO:00099662250.073
agingGO:000756820.073
regulation of cellular metabolic processGO:00313233200.072
phosphate containing compound metabolic processGO:00067961080.072
heart developmentGO:00075073130.069
regulation of biosynthetic processGO:00098892500.067
programmed cell deathGO:00125011190.066
regulation of protein transportGO:005122330.066
stem cell divisionGO:001714510.066
regulation of dendrite developmentGO:005077330.066
regulation of apoptotic processGO:0042981980.065
positive regulation of cell cycleGO:004578730.064
regulation of gene expressionGO:00104682650.063
positive regulation of neurogenesisGO:0050769240.061
nucleobase containing compound metabolic processGO:00061392740.060
positive regulation of purine nucleotide catabolic processGO:003312310.060
organic substance biosynthetic processGO:19015762890.059
protein localization to nucleusGO:003450430.057
enzyme linked receptor protein signaling pathwayGO:00071671060.057
organic cyclic compound metabolic processGO:19013603010.057
sensory perception of touchGO:005097520.056
regulation of programmed cell deathGO:00430671010.055
biological adhesionGO:0022610400.055
carbohydrate derivative biosynthetic processGO:1901137430.053
embryonic organ developmentGO:00485683810.053
heterocycle metabolic processGO:00464832900.052
striated muscle cell differentiationGO:00511461290.051
regulation of neuron differentiationGO:0045664560.051
organonitrogen compound metabolic processGO:1901564740.051
generation of neuronsGO:00486993850.051
regulation of response to stimulusGO:00485832690.050
developmental cell growthGO:0048588520.050
regulation of cell projection organizationGO:0031344440.050
neuron projection developmentGO:00311751800.049
regulation of cell deathGO:00109411030.049
neuron developmentGO:00486662620.049
cell part morphogenesisGO:00329902460.049
intracellular signal transductionGO:0035556850.048
positive regulation of biological processGO:00485182530.048
positive regulation of oocyte developmentGO:006028210.048
regulation of synapse assemblyGO:005196330.047
deathGO:00162651210.047
regulation of nervous system developmentGO:0051960900.047
regulation of cell morphogenesisGO:0022604420.047
extrinsic apoptotic signaling pathwayGO:009719130.045
nucleocytoplasmic transportGO:000691340.045
regulation of primary metabolic processGO:00800903110.045
single organism metabolic processGO:00447102170.045
regulation of neuron projection developmentGO:0010975400.045
small gtpase mediated signal transductionGO:000726480.044
positive regulation of catabolic processGO:000989640.042
maintenance of locationGO:005123540.042
localization of cellGO:00516742440.042
positive regulation of cellular catabolic processGO:003133130.041
positive regulation of cell developmentGO:0010720250.041
actin filament organizationGO:0007015150.041
regulation of neurogenesisGO:0050767870.041
regulation of nucleoside metabolic processGO:000911820.041
aromatic compound biosynthetic processGO:00194382170.040
developmental growthGO:00485891660.040
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.039
epithelial tube morphogenesisGO:00605621480.039
cellular protein modification processGO:00064641000.039
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.039
segmentationGO:0035282970.039
cell morphogenesis involved in differentiationGO:00009041950.038
regulation of signalingGO:00230512350.038
embryonic heart tube developmentGO:00350501330.038
locomotionGO:00400113130.036
establishment of localization in cellGO:0051649770.036
hemopoiesisGO:00300971830.036
positive regulation of gtp catabolic processGO:003312610.036
single organism transportGO:00447652060.036
guanosine containing compound metabolic processGO:190106840.035
energy reserve metabolic processGO:000611220.035
regulation of protein localization to nucleusGO:190018020.035
cell deathGO:00082191210.035
axon developmentGO:00615641660.035
fatty acid oxidationGO:001939510.035
cell adhesionGO:0007155400.034
negative regulation of cellular processGO:00485232830.034
cellular biosynthetic processGO:00442492860.034
negative regulation of synapse assemblyGO:005196420.034
regulation of i kappab kinase nf kappab signalingGO:004312240.034
neuroblast proliferationGO:000740520.033
establishment of protein localization to organelleGO:007259440.033
regulation of protein targetingGO:190353320.033
cellular nitrogen compound biosynthetic processGO:00442712180.033
positive regulation of nucleotide catabolic processGO:003081310.033
digestive system developmentGO:00551232890.033
protein importGO:001703830.033
reflexGO:006000420.032
regulation of nitrogen compound metabolic processGO:00511712510.032
endoderm developmentGO:0007492490.032
cell surface receptor signaling pathwayGO:00071663250.032
regulation of biological qualityGO:00650082630.032
cellular component morphogenesisGO:00329893360.031
regulation of metabolic processGO:00192223590.031
carbohydrate derivative metabolic processGO:1901135610.031
regulation of intracellular signal transductionGO:1902531570.031
positive regulation of nervous system developmentGO:0051962250.031
purine nucleoside monophosphate catabolic processGO:000912840.031
biosynthetic processGO:00090582940.031
neural precursor cell proliferationGO:0061351200.030
amine metabolic processGO:000930820.030
embryonic hemopoiesisGO:0035162530.030
regulation of intracellular protein transportGO:003315730.030
regulation of protein import into nucleusGO:004230620.030
cortical actin cytoskeleton organizationGO:003086610.029
negative regulation of biological processGO:00485193040.029
peptidyl serine phosphorylationGO:001810510.029
macromolecule modificationGO:00434121110.029
cognitionGO:005089010.029
cell fate commitmentGO:0045165990.028
cyclic purine nucleotide metabolic processGO:0052652180.028
synaptic growth at neuromuscular junctionGO:005112420.028
hematopoietic or lymphoid organ developmentGO:00485341910.028
dorsal ventral pattern formationGO:00099531250.028
cellular amine metabolic processGO:004410620.028
establishment of localizationGO:00512342440.028
stem cell proliferationGO:007208940.028
single organism biosynthetic processGO:0044711710.027
muscle cell differentiationGO:00426921390.027
regulation of establishment of protein localizationGO:007020140.027
regulation of anatomical structure morphogenesisGO:00226031300.027
cellular component movementGO:00069283350.027
response to chemicalGO:00422213200.027
transportGO:00068102200.027
nuclear transportGO:005116940.027
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.027
negative regulation of cell deathGO:0060548600.027
protein modification processGO:00362111000.027
regionalizationGO:00030022740.026
regulation of purine nucleotide biosynthetic processGO:1900371150.026
axonogenesisGO:00074091520.026
translational initiationGO:000641330.026
gtp catabolic processGO:000618420.026
cell projection organizationGO:00300302840.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.026
regulation of phosphorus metabolic processGO:0051174430.025
muscle fiber developmentGO:0048747520.025
regulation of purine nucleotide catabolic processGO:003312120.025
regulation of cellular amino acid metabolic processGO:000652100.025
endosome organizationGO:000703220.024
small molecule metabolic processGO:0044281770.024
actin filament polymerizationGO:003004120.024
heterocycle biosynthetic processGO:00181302150.024
nuclear importGO:005117030.024
gtp metabolic processGO:004603940.024
microtubule based processGO:0007017600.024
regulation of macromolecule biosynthetic processGO:00105562250.023
cytoskeleton dependent cytokinesisGO:006164030.023
protein targeting to nucleusGO:004474430.023
regulation of rna biosynthetic processGO:20011412130.023
blood vessel morphogenesisGO:00485142160.023
cellular protein metabolic processGO:00442671290.023
regulation of muscle hypertrophyGO:001474320.023
oxoacid metabolic processGO:0043436310.023
protein import into nucleusGO:000660630.023
cytokinesisGO:000091030.023
response to external stimulusGO:00096052640.023
cellular component disassemblyGO:002241110.023
response to stressGO:00069502630.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
regulation of locomotionGO:0040012550.022
ras protein signal transductionGO:000726570.022
cortical cytoskeleton organizationGO:003086510.022
lipid storageGO:001991510.022
macromolecule biosynthetic processGO:00090592270.022
cellular response to chemical stimulusGO:00708871570.021
larval developmentGO:000216420.021
negative regulation of apoptotic processGO:0043066550.021
regulation of metal ion transportGO:001095940.021
positive regulation of cellular processGO:00485222010.021
definitive hemopoiesisGO:0060216180.021
positive regulation of cell projection organizationGO:003134690.021
rho protein signal transductionGO:000726650.021
nucleoside phosphate biosynthetic processGO:1901293210.021
single organism nuclear importGO:190259330.021
skeletal muscle fiber developmentGO:0048741350.021
behaviorGO:0007610740.020
reactive oxygen species metabolic processGO:007259360.020
ribose phosphate biosynthetic processGO:0046390200.020
positive regulation of muscle cell differentiationGO:005114910.020
erythrocyte homeostasisGO:0034101550.020
regulation of cellular amine metabolic processGO:003323800.020
centrosome organizationGO:005129710.020
cytoskeleton organizationGO:0007010960.020
ribonucleoside monophosphate catabolic processGO:000915840.020
positive regulation of i kappab kinase nf kappab signalingGO:004312330.020
regulation of dna replicationGO:000627530.020
regulation of transcription dna templatedGO:00063552130.020
positive regulation of developmental processGO:0051094500.020
protein localization to plasma membraneGO:007265910.020
growthGO:00400071740.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
regulation of gtpase activityGO:004308720.020
single organism cellular localizationGO:1902580460.020
mitotic cell cycleGO:0000278640.019
protein secretionGO:000930610.019
myeloid cell differentiationGO:0030099860.019
single organism organelle organizationGO:19025891990.019
cellular amino acid metabolic processGO:000652070.019
regulation of nucleocytoplasmic transportGO:004682220.019
nucleic acid templated transcriptionGO:00976591810.019
cell migration involved in gastrulationGO:0042074790.019
regulation of phosphate metabolic processGO:0019220430.019
response to hydrogen peroxideGO:004254230.019
macromolecule localizationGO:0033036540.019
nucleotide metabolic processGO:0009117280.019
single organism membrane fusionGO:004480120.019
nucleoside monophosphate catabolic processGO:000912540.019
muscle structure developmentGO:00610611960.019
phosphorylationGO:0016310690.019
convergent extension involved in gastrulationGO:0060027710.019
positive regulation of cellular metabolic processGO:0031325940.019
rna metabolic processGO:00160702190.018
multicellular organismal metabolic processGO:004423620.018
atp catabolic processGO:000620040.018
membrane invaginationGO:001032410.018
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.018
regulation of erk1 and erk2 cascadeGO:007037240.018
regulation of cytoplasmic transportGO:190364940.018
macromolecular complex subunit organizationGO:0043933740.018
defense response to fungusGO:005083220.018
regulation of bmp signaling pathwayGO:0030510390.018
regulation of ras gtpase activityGO:003231820.018
positive regulation of cellular component biogenesisGO:004408930.018
protein polymerizationGO:005125840.018
phagocytosis engulfmentGO:000691110.018
macromolecular complex disassemblyGO:003298410.018
negative regulation of mapk cascadeGO:004340940.018
positive regulation of nucleoside metabolic processGO:004597910.018
regulation of cellular ketone metabolic processGO:001056570.018
protein dephosphorylationGO:000647030.018
regulation of extrinsic apoptotic signaling pathwayGO:200123630.018
detection of stimulus involved in sensory perceptionGO:0050906210.018
modification dependent macromolecule catabolic processGO:004363230.018
meiotic cell cycle processGO:190304630.018
mesoderm developmentGO:0007498880.018
positive regulation of ras gtpase activityGO:003232010.017
digestive tract morphogenesisGO:00485462310.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of glucose transportGO:001082710.017
protein depolymerizationGO:005126110.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
regulation of cell communicationGO:00106462320.017
establishment of cell polarityGO:0030010180.017
nuclear migrationGO:000709730.017
regulation of oocyte developmentGO:006028130.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
i kappab kinase nf kappab signalingGO:000724940.017
monocyte differentiationGO:003022420.017
positive regulation of signalingGO:0023056560.017
regulation of developmental growthGO:0048638380.017
positive regulation of neuron differentiationGO:0045666120.017
cell fate commitment involved in formation of primary germ layerGO:0060795260.017
guanosine containing compound catabolic processGO:190106920.017
response to bacteriumGO:0009617580.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.017
purine containing compound metabolic processGO:0072521290.017
muscle cell migrationGO:001481240.016
neurological system processGO:0050877620.016
cell substrate adhesionGO:003158940.016
response to glucoseGO:000974930.016
nephron tubule morphogenesisGO:007207810.016
regulation of cellular biosynthetic processGO:00313262450.016
organic cyclic compound biosynthetic processGO:19013622230.016
regulation of transmembrane transporter activityGO:002289820.016
response to nutrientGO:000758430.016
determination of left right symmetryGO:00073681790.016
post golgi vesicle mediated transportGO:000689210.016
regulation of response to biotic stimulusGO:000283120.016
muscle organ developmentGO:00075171010.016
negative regulation of map kinase activityGO:004340720.016
carbohydrate biosynthetic processGO:001605110.016
negative regulation of response to stimulusGO:00485851040.016
establishment of mitotic spindle localizationGO:0040001120.016
negative regulation of protein localization to nucleusGO:190018120.016
regulation of anatomical structure sizeGO:0090066330.016
negative chemotaxisGO:005091910.015
regulation of skeletal muscle fiber developmentGO:004874220.015
positive regulation of cell divisionGO:005178120.015
cellular response to stressGO:0033554620.015
protein metabolic processGO:00195381830.015
negative regulation of immune responseGO:005077720.015
regulation of canonical wnt signaling pathwayGO:0060828340.015
establishment of mitotic spindle orientationGO:0000132100.015
cellular ketone metabolic processGO:0042180110.015
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.015
regulation of protein polymerizationGO:003227120.015
regulation of nucleotide catabolic processGO:003081120.015
gastrulationGO:00073692080.015
cellular localizationGO:0051641970.015
negative regulation of protein transportGO:005122430.015
nucleobase containing compound biosynthetic processGO:00346542050.015
wound healingGO:0042060900.014
organic substance transportGO:0071702580.014
nephron epithelium morphogenesisGO:007208810.014
regulation of transporter activityGO:003240920.014
vascular endothelial growth factor receptor signaling pathwayGO:0048010130.014
positive regulation of cellular biosynthetic processGO:0031328680.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
response to abiotic stimulusGO:00096281220.014
erk1 and erk2 cascadeGO:007037140.014
regulation of cell sizeGO:0008361290.014
osteoclast differentiationGO:003031610.014
negative regulation of nucleocytoplasmic transportGO:004682320.014
microtubule organizing center organizationGO:003102310.014
regulation of response to external stimulusGO:0032101310.014
response to woundingGO:00096111160.014
peptide transportGO:001583310.014
histone phosphorylationGO:001657220.014
tube morphogenesisGO:00352393490.014
negative regulation of developmental processGO:0051093650.014
purine ribonucleotide metabolic processGO:0009150270.014
regulation of nucleic acid templated transcriptionGO:19035062130.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.013
regulation of calcium ion transportGO:005192420.013
positive regulation of gtpase activityGO:004354710.013
regulation of cell substrate adhesionGO:001081010.013
system processGO:00030081850.013
membrane fusionGO:006102520.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
cellular response to molecule of bacterial originGO:007121930.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
organic acid metabolic processGO:0006082310.013
negative regulation of protein kinase activityGO:000646940.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.013
regulation of purine nucleotide metabolic processGO:1900542170.013
actin filament based processGO:0030029640.013
protein complex disassemblyGO:004324110.013
regulation of dendrite morphogenesisGO:004881430.013
cellular response to biotic stimulusGO:007121630.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
negative regulation of defense responseGO:003134820.013
actin polymerization or depolymerizationGO:000815420.013
mapk cascadeGO:0000165180.013
germ line stem cell maintenanceGO:003071820.013
retina development in camera type eyeGO:00600411460.013
superoxide metabolic processGO:000680120.013
negative regulation of intracellular transportGO:003238730.013
meiosis iGO:000712710.013
stem cell maintenanceGO:001982740.013
single organism intracellular transportGO:1902582250.013
single organism localizationGO:19025782250.013
immune system processGO:00023762410.012
positive regulation of response to stimulusGO:0048584800.012
organelle fusionGO:004828430.012
g1 s transition of mitotic cell cycleGO:000008210.012
gene expressionGO:00104672520.012
positive regulation of dna metabolic processGO:005105410.012
transcription dna templatedGO:00063511810.012
heart morphogenesisGO:00030071560.012
neuron projection extensionGO:1990138450.012
ribonucleotide biosynthetic processGO:0009260200.012
microtubule cytoskeleton organizationGO:0000226330.012
cytokinetic processGO:003250620.012
positive regulation of biosynthetic processGO:0009891680.012
negative regulation of ras protein signal transductionGO:004658010.012
cyclic nucleotide metabolic processGO:0009187180.012
ameboidal type cell migrationGO:00016671430.012
lamellipodium organizationGO:009758110.012
adherens junction organizationGO:003433240.012
regulation of bone mineralizationGO:003050020.012
cellular response to lipopolysaccharideGO:007122230.012
regulation of cell cycleGO:0051726520.012
proteasomal protein catabolic processGO:001049820.012
modification dependent protein catabolic processGO:001994130.012
golgi vesicle transportGO:004819330.012
sensory perception of painGO:001923310.012
positive regulation of synapse assemblyGO:005196510.012
positive regulation of cell communicationGO:0010647560.012
regulation of bindingGO:005109830.012
convergent extensionGO:00600261180.012
positive regulation of glucose importGO:004632610.012
negative regulation of programmed cell deathGO:0043069580.012
regulation of establishment of protein localization to plasma membraneGO:009000310.012
actin cytoskeleton organizationGO:0030036630.012
negative regulation of intracellular protein transportGO:009031730.012
regulation of protein complex disassemblyGO:004324410.012
positive regulation of cellular component organizationGO:0051130130.012
cell migrationGO:00164772370.011
canonical wnt signaling pathwayGO:0060070480.011
organelle localizationGO:0051640490.011
response to external biotic stimulusGO:0043207970.011
meiotic nuclear divisionGO:000712640.011
regenerationGO:0031099910.011
regulation of molecular functionGO:0065009700.011
regulation of protein depolymerizationGO:190187910.011
formation of primary germ layerGO:0001704620.011
er to golgi vesicle mediated transportGO:000688810.011
positive regulation of signal transductionGO:0009967560.011
establishment of spindle orientationGO:0051294100.011
myeloid cell homeostasisGO:0002262560.011
nucleoside phosphate metabolic processGO:0006753280.011
positive regulation of striated muscle tissue developmentGO:004584410.011
cellular response to extracellular stimulusGO:003166820.011
bmp signaling pathwayGO:0030509520.011
positive regulation of glucose transportGO:001082810.011
carboxylic acid metabolic processGO:0019752220.011
axon guidanceGO:0007411860.011
cellular response to organic substanceGO:00713101050.011
positive regulation of metabolic processGO:00098931080.011
regulation of rho protein signal transductionGO:003502320.011
single organism cell adhesionGO:0098602290.011
negative regulation of protein import into nucleusGO:004230820.011
protein complex subunit organizationGO:0071822460.011
ribose phosphate metabolic processGO:0019693270.011
regulation of carbohydrate metabolic processGO:000610940.011
positive regulation of cytoskeleton organizationGO:005149530.011
regulation of cellular carbohydrate metabolic processGO:001067540.010
positive regulation of rho protein signal transductionGO:003502500.010
regulation of wnt signaling pathwayGO:0030111530.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.010
heparan sulfate proteoglycan biosynthetic processGO:001501250.010
receptor internalizationGO:003162320.010
cellular modified amino acid metabolic processGO:000657530.010
negative regulation of cell communicationGO:0010648960.010
chemotaxisGO:00069351040.010
positive regulation of erk1 and erk2 cascadeGO:007037420.010
negative regulation of innate immune responseGO:004582420.010
purine nucleotide biosynthetic processGO:0006164200.010
positive regulation of secretionGO:005104710.010
anterior posterior pattern specificationGO:00099521520.010
brain morphogenesisGO:0048854180.010
regulation of nucleobase containing compound metabolic processGO:00192192500.010
cellular protein catabolic processGO:004425740.010
regulation of macromolecule metabolic processGO:00602553170.010
vasculature developmentGO:00019442780.010
primary neural tube formationGO:001402010.010
cellular macromolecule biosynthetic processGO:00346452240.010

diaph2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone marrow diseaseDOID:496100.085
disease of anatomical entityDOID:700.085
hematopoietic system diseaseDOID:7400.085
immune system diseaseDOID:291400.085
disease of metabolismDOID:001466700.037
congenital hypoplastic anemiaDOID:134200.032
aplastic anemiaDOID:1244900.032
anemiaDOID:235500.032
inherited metabolic disorderDOID:65500.023
amyloidosisDOID:912000.012
acquired metabolic diseaseDOID:006015800.012
disease of cellular proliferationDOID:1456600.011