IMP: Integrative Multi-species Prediction

Danio rerio

79 known processes

epb41l5

erythrocyte membrane protein band 4.1 like 5

(Aliases: dZ104F18.3,KIAA1548,si:dz37o5.2,si:dz104f18.3,si:dz104f18.2)

Ensembl: ENSDARG00000032324
ZFIN: ZDB-GENE-030616-450
Entrez: 368449
UniProtKB: Q6NYK4
UniProtKB: Q6PNC5

Process Predictions
Disease Predictions

epb41l5 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
sensory organ morphogenesis	GO:0090596	200	0.997
central nervous system development	GO:0007417	387	0.989
neuron differentiation	GO:0030182	353	0.981	Fly
establishment or maintenance of apical basal cell polarity	GO:0035088	12	0.978
eye development	GO:0001654	277	0.977
apical protein localization	GO:0045176	6	0.972
eye morphogenesis	GO:0048592	144	0.971
brain development	GO:0007420	293	0.966
retina development in camera type eye	GO:0060041	146	0.962
establishment or maintenance of epithelial cell apical basal polarity	GO:0045197	11	0.955
retina morphogenesis in camera type eye	GO:0060042	79	0.953
cell projection morphogenesis	GO:0048858	244	0.951
single organism organelle organization	GO:1902589	199	0.936	Mouse
cilium morphogenesis	GO:0060271	85	0.935
sensory organ development	GO:0007423	393	0.929
head development	GO:0060322	303	0.913
cell projection organization	GO:0030030	284	0.901
morphogenesis of an epithelium	GO:0002009	333	0.901	Mouse Fly
cilium assembly	GO:0042384	58	0.890
neuron development	GO:0048666	262	0.890	Fly
multicellular organismal homeostasis	GO:0048871	29	0.875	Fly
medulla oblongata development	GO:0021550	4	0.872
nonmotile primary cilium assembly	GO:0035058	2	0.867
photoreceptor cell differentiation	GO:0046530	55	0.847	Fly
camera type eye morphogenesis	GO:0048593	108	0.831
eye photoreceptor cell differentiation	GO:0001754	45	0.818	Fly
digestive tract development	GO:0048565	265	0.798	Mouse
epithelial tube formation	GO:0072175	19	0.793
epidermis development	GO:0008544	48	0.790
digestive tract morphogenesis	GO:0048546	231	0.789	Mouse
neural tube development	GO:0021915	62	0.781
organelle organization	GO:0006996	227	0.776	Mouse
camera type eye development	GO:0043010	222	0.771
homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	4	0.770
negative regulation of cellular process	GO:0048523	283	0.764	Mouse
negative regulation of biological process	GO:0048519	304	0.753	Mouse
embryonic heart tube development	GO:0035050	133	0.747
skin development	GO:0043588	54	0.742
heart development	GO:0007507	313	0.732
signal transduction	GO:0007165	455	0.729
embryonic organ morphogenesis	GO:0048562	274	0.727
neural tube formation	GO:0001841	16	0.721
embryonic organ development	GO:0048568	381	0.719
cellular component morphogenesis	GO:0032989	336	0.671	Mouse
cilium organization	GO:0044782	71	0.671
notch signaling pathway	GO:0007219	35	0.666
regulation of multicellular organismal development	GO:2000026	223	0.660	Mouse
morphogenesis of embryonic epithelium	GO:0016331	30	0.655	Mouse Fly
digestive system development	GO:0055123	289	0.646	Mouse
cellular component biogenesis	GO:0044085	178	0.630	Mouse
cellular component assembly	GO:0022607	170	0.629	Mouse
cell part morphogenesis	GO:0032990	246	0.604
cellular component movement	GO:0006928	335	0.594	Mouse
tube formation	GO:0035148	25	0.582
cell projection assembly	GO:0030031	64	0.579
generation of neurons	GO:0048699	385	0.576	Fly
cell morphogenesis	GO:0000902	289	0.572	Mouse
response to abiotic stimulus	GO:0009628	122	0.561
heart morphogenesis	GO:0003007	156	0.557
ear development	GO:0043583	127	0.556
cellular component assembly involved in morphogenesis	GO:0010927	107	0.555
regulation of cellular metabolic process	GO:0031323	320	0.544
locomotion	GO:0040011	313	0.539	Mouse
embryonic heart tube morphogenesis	GO:0003143	108	0.538
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules	GO:0007157	2	0.530
epidermal cell differentiation	GO:0009913	36	0.526
microtubule based movement	GO:0007018	33	0.515
regulation of neurogenesis	GO:0050767	87	0.507
neurological system process	GO:0050877	62	0.504
hair cell differentiation	GO:0035315	32	0.479
tissue homeostasis	GO:0001894	25	0.466	Fly
transport	GO:0006810	220	0.465
regulation of multicellular organismal process	GO:0051239	277	0.464	Mouse
establishment of epithelial cell polarity	GO:0090162	2	0.450	Fly
establishment or maintenance of polarity of embryonic epithelium	GO:0016332	2	0.447
hindbrain development	GO:0030902	91	0.444
asymmetric protein localization	GO:0008105	6	0.442
dorsal motor nucleus of vagus nerve development	GO:0021744	4	0.417
gliogenesis	GO:0042063	45	0.417
neuron projection development	GO:0031175	180	0.413
system process	GO:0003008	185	0.406
cell migration	GO:0016477	237	0.405	Mouse
establishment of localization	GO:0051234	244	0.404	Mouse
primary neural tube formation	GO:0014020	1	0.399
maintenance of cell polarity	GO:0030011	5	0.391
determination of bilateral symmetry	GO:0009855	204	0.381
establishment or maintenance of bipolar cell polarity	GO:0061245	12	0.376
maintenance of epithelial cell apical basal polarity	GO:0045199	5	0.362
establishment or maintenance of cell polarity	GO:0007163	29	0.357
tube morphogenesis	GO:0035239	349	0.345	Mouse
anatomical structure homeostasis	GO:0060249	36	0.339	Fly
homeostatic process	GO:0042592	142	0.330	Fly
embryo development ending in birth or egg hatching	GO:0009792	271	0.322	Mouse Fly
chordate embryonic development	GO:0043009	271	0.319	Mouse
wnt signaling pathway	GO:0016055	80	0.316
establishment of cell polarity	GO:0030010	18	0.313	Fly
regulation of nervous system development	GO:0051960	90	0.311
nitrogen compound metabolic process	GO:0006807	319	0.310
determination of heart left right asymmetry	GO:0061371	117	0.308
larval development	GO:0002164	2	0.303
inner ear receptor cell differentiation	GO:0060113	29	0.298
cellular localization	GO:0051641	97	0.297
developmental growth involved in morphogenesis	GO:0060560	86	0.296	Mouse
negative regulation of response to stimulus	GO:0048585	104	0.282
regulation of notch signaling pathway	GO:0008593	16	0.281
regulation of signal transduction	GO:0009966	225	0.281
pronephros development	GO:0048793	69	0.279
epithelial tube morphogenesis	GO:0060562	148	0.276
macromolecular complex subunit organization	GO:0043933	74	0.272
eye photoreceptor cell development	GO:0042462	30	0.268	Fly
regulation of developmental process	GO:0050793	247	0.266	Mouse
gastrulation	GO:0007369	208	0.252	Mouse
regulation of biological quality	GO:0065008	263	0.252	Fly
gene expression	GO:0010467	252	0.248	Mouse
cytoskeleton organization	GO:0007010	96	0.239	Mouse
cell cycle	GO:0007049	93	0.238
regulation of cell projection organization	GO:0031344	44	0.236
protein complex subunit organization	GO:0071822	46	0.233
mitotic cell cycle	GO:0000278	64	0.232
microtubule based process	GO:0007017	60	0.226
regulation of cell death	GO:0010941	103	0.225
epithelial cell differentiation	GO:0030855	116	0.223	Mouse Fly
specification of symmetry	GO:0009799	204	0.213
cell motility	GO:0048870	244	0.210	Mouse
sensory perception of mechanical stimulus	GO:0050954	16	0.207
response to external stimulus	GO:0009605	264	0.202
embryonic retina morphogenesis in camera type eye	GO:0060059	22	0.201
single organismal cell cell adhesion	GO:0016337	29	0.199	Mouse
negative regulation of signaling	GO:0023057	96	0.197
cellular aromatic compound metabolic process	GO:0006725	295	0.193
heterocycle biosynthetic process	GO:0018130	215	0.193
negative regulation of notch signaling pathway	GO:0045746	6	0.192
retina homeostasis	GO:0001895	12	0.191
axon development	GO:0061564	166	0.190
regulation of signaling	GO:0023051	235	0.190
midbrain development	GO:0030901	28	0.188
response to light stimulus	GO:0009416	46	0.186
inner ear receptor stereocilium organization	GO:0060122	8	0.184
visual perception	GO:0007601	17	0.183
neural nucleus development	GO:0048857	15	0.182
adherens junction maintenance	GO:0034334	2	0.180
auditory receptor cell differentiation	GO:0042491	15	0.179
photoreceptor cell maintenance	GO:0045494	11	0.178
peripheral nervous system development	GO:0007422	55	0.176
cellular response to radiation	GO:0071478	4	0.175
regulation of macromolecule biosynthetic process	GO:0010556	225	0.173
mitotic cell cycle process	GO:1903047	48	0.171
retina layer formation	GO:0010842	24	0.170
regulation of response to stimulus	GO:0048583	269	0.169
nucleobase containing compound metabolic process	GO:0006139	274	0.169
gland development	GO:0048732	143	0.167
neuron projection morphogenesis	GO:0048812	161	0.167
regulation of cell differentiation	GO:0045595	142	0.165	Mouse
negative regulation of signal transduction	GO:0009968	94	0.164
regulation of wnt signaling pathway	GO:0030111	53	0.164
single organism localization	GO:1902578	225	0.162
renal filtration	GO:0097205	10	0.160
cell death	GO:0008219	121	0.159
apoptotic process	GO:0006915	116	0.158
glial cell proliferation	GO:0014009	4	0.158
polarized epithelial cell differentiation	GO:0030859	4	0.157	Fly
cell surface receptor signaling pathway	GO:0007166	325	0.157
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.156
establishment of monopolar cell polarity	GO:0061162	2	0.155	Fly
phosphorus metabolic process	GO:0006793	109	0.154
death	GO:0016265	121	0.154
neural tube patterning	GO:0021532	33	0.150
positive regulation of biological process	GO:0048518	253	0.145
glomerulus development	GO:0032835	27	0.144
adherens junction organization	GO:0034332	4	0.142	Mouse
regulation of axonogenesis	GO:0050770	32	0.139
determination of left right symmetry	GO:0007368	179	0.136
heart looping	GO:0001947	94	0.135
response to radiation	GO:0009314	51	0.135
cellular macromolecule metabolic process	GO:0044260	391	0.134
axonogenesis	GO:0007409	152	0.133
regionalization	GO:0003002	274	0.132	Mouse
positive regulation of glial cell proliferation	GO:0060252	1	0.131
programmed cell death	GO:0012501	119	0.130
organic substance biosynthetic process	GO:1901576	289	0.130
cellular biosynthetic process	GO:0044249	286	0.128
catabolic process	GO:0009056	32	0.126
regulation of metabolic process	GO:0019222	359	0.125	Mouse
regulation of primary metabolic process	GO:0080090	311	0.122
cellular protein metabolic process	GO:0044267	129	0.122
digestive tract mesoderm development	GO:0007502	1	0.121
positive regulation of gliogenesis	GO:0014015	2	0.121
inner ear development	GO:0048839	126	0.119
regulation of neuron differentiation	GO:0045664	56	0.119
regulation of programmed cell death	GO:0043067	101	0.119
taxis	GO:0042330	109	0.118
negative regulation of cell communication	GO:0010648	96	0.117
nerve development	GO:0021675	45	0.115
regulation of macromolecule metabolic process	GO:0060255	317	0.115	Mouse
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.114
heterocycle metabolic process	GO:0046483	290	0.114
autophagy	GO:0006914	4	0.114
hepaticobiliary system development	GO:0061008	98	0.112
chemotaxis	GO:0006935	104	0.112
glial cell differentiation	GO:0010001	42	0.109
rna biosynthetic process	GO:0032774	181	0.109
embryonic epithelial tube formation	GO:0001838	17	0.107
response to chemical	GO:0042221	320	0.106	Mouse
tube closure	GO:0060606	1	0.106
epithelium migration	GO:0090132	25	0.106	Mouse
positive regulation of developmental process	GO:0051094	50	0.105	Mouse
cellular response to organic substance	GO:0071310	105	0.104	Mouse
cell cell junction maintenance	GO:0045217	1	0.103
regulation of localization	GO:0032879	104	0.102	Mouse
homeostasis of number of cells within a tissue	GO:0048873	4	0.102
embryonic hemopoiesis	GO:0035162	53	0.102
establishment of spindle localization	GO:0051293	12	0.102
neuroblast proliferation	GO:0007405	2	0.100
regulation of gene expression	GO:0010468	265	0.100	Mouse
establishment of localization in cell	GO:0051649	77	0.100
rna metabolic process	GO:0016070	219	0.099
sensory perception of light stimulus	GO:0050953	19	0.099
positive regulation of glucose transport	GO:0010828	1	0.098
cellular nitrogen compound metabolic process	GO:0034641	290	0.098
regulation of cell communication	GO:0010646	232	0.096
positive regulation of purine nucleotide metabolic process	GO:1900544	9	0.096
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.095
mechanoreceptor differentiation	GO:0042490	37	0.094
muscle tissue development	GO:0060537	110	0.094
morphogenesis of an epithelial sheet	GO:0002011	49	0.094
cell junction maintenance	GO:0034331	2	0.093
anterior posterior pattern specification	GO:0009952	152	0.092	Mouse
cell cell adhesion	GO:0098609	6	0.092
chemosensory behavior	GO:0007635	1	0.092
olfactory lobe development	GO:0021988	4	0.090
single organism transport	GO:0044765	206	0.089
renal system development	GO:0072001	94	0.088
exocrine system development	GO:0035272	28	0.085
immune system development	GO:0002520	191	0.085
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	6	0.085
positive regulation of nucleoside metabolic process	GO:0045979	1	0.085
protein modification process	GO:0036211	100	0.085
establishment of mitotic spindle localization	GO:0040001	12	0.084
spinal cord development	GO:0021510	46	0.084
positive regulation of purine nucleotide catabolic process	GO:0033123	1	0.083
meiotic nuclear division	GO:0007126	4	0.083
macromolecule biosynthetic process	GO:0009059	227	0.082
cellular protein modification process	GO:0006464	100	0.082
cellular macromolecule biosynthetic process	GO:0034645	224	0.081
organelle assembly	GO:0070925	110	0.079
protein metabolic process	GO:0019538	183	0.078
transcription dna templated	GO:0006351	181	0.078
regulation of neuron projection development	GO:0010975	40	0.077
regulation of cell morphogenesis	GO:0022604	42	0.077	Mouse
stem cell proliferation	GO:0072089	4	0.077
cell morphogenesis involved in differentiation	GO:0000904	195	0.075	Mouse
lateral line system development	GO:0048925	76	0.075
regulation of glucose transport	GO:0010827	1	0.074
kidney development	GO:0001822	92	0.073
localization of cell	GO:0051674	244	0.073	Mouse
regulation of anatomical structure morphogenesis	GO:0022603	130	0.072	Mouse
smoothened signaling pathway	GO:0007224	30	0.071
astrocyte differentiation	GO:0048708	1	0.070
cellular response to chemical stimulus	GO:0070887	157	0.070	Mouse
mesoderm development	GO:0007498	88	0.069	Mouse
single organism metabolic process	GO:0044710	217	0.069
ameboidal type cell migration	GO:0001667	143	0.069	Mouse
protein localization	GO:0008104	40	0.068
neuron projection guidance	GO:0097485	86	0.067
forebrain development	GO:0030900	96	0.067
cellular response to extracellular stimulus	GO:0031668	2	0.065
negative regulation of epithelial cell proliferation	GO:0050680	1	0.065
axoneme assembly	GO:0035082	9	0.065
carboxylic acid metabolic process	GO:0019752	22	0.065
mrna metabolic process	GO:0016071	20	0.064
swim bladder development	GO:0048794	19	0.064
nucleobase containing compound biosynthetic process	GO:0034654	205	0.064
cellular component maintenance	GO:0043954	3	0.064
microtubule cytoskeleton organization	GO:0000226	33	0.064
somatic stem cell maintenance	GO:0035019	1	0.063
mitochondrion organization	GO:0007005	4	0.062
segmentation	GO:0035282	97	0.062	Mouse
neural retina development	GO:0003407	49	0.061
embryonic pattern specification	GO:0009880	44	0.061	Mouse
developmental growth	GO:0048589	166	0.061	Mouse
negative regulation of wnt signaling pathway	GO:0030178	30	0.061
organic cyclic compound metabolic process	GO:1901360	301	0.060
intracellular signal transduction	GO:0035556	85	0.060
regulation of cell development	GO:0060284	100	0.060	Mouse
glomerular filtration	GO:0003094	6	0.059
protein complex assembly	GO:0006461	30	0.059
response to stress	GO:0006950	263	0.059
positive regulation of cellular catabolic process	GO:0031331	3	0.059
epithelial cilium movement	GO:0003351	15	0.059
response to carbohydrate	GO:0009743	3	0.058
rna 3 end processing	GO:0031123	2	0.058
positive regulation of transport	GO:0051050	2	0.058
negative regulation of canonical wnt signaling pathway	GO:0090090	21	0.058
sensory perception	GO:0007600	39	0.057
liver development	GO:0001889	96	0.057
spinal cord patterning	GO:0021511	6	0.057
spindle localization	GO:0051653	12	0.057
neuron migration	GO:0001764	22	0.057
epithelial structure maintenance	GO:0010669	8	0.056
regulation of cellular component organization	GO:0051128	86	0.056	Mouse
cranial nerve development	GO:0021545	42	0.056
cellular response to external stimulus	GO:0071496	2	0.056
multi organism process	GO:0051704	134	0.055
atp catabolic process	GO:0006200	4	0.054
cellular ketone metabolic process	GO:0042180	11	0.054
biological adhesion	GO:0022610	40	0.054	Mouse
intraciliary transport	GO:0042073	7	0.054
odontogenesis	GO:0042476	9	0.053
appendage development	GO:0048736	80	0.053
regulation of glucose import	GO:0046324	1	0.053
positive regulation of cellular component biogenesis	GO:0044089	3	0.053	Mouse
establishment of nucleus localization	GO:0040023	7	0.053
cellular response to starvation	GO:0009267	1	0.052
regulation of molecular function	GO:0065009	70	0.052	Mouse
nuclear migration	GO:0007097	3	0.052
regulation of apoptotic process	GO:0042981	98	0.051
maintenance of location	GO:0051235	4	0.051
spinal cord dorsal ventral patterning	GO:0021513	5	0.051
commissural neuron axon guidance	GO:0071679	3	0.049
erythrocyte maturation	GO:0043249	8	0.049
exocytosis	GO:0006887	1	0.049
maintenance of gastrointestinal epithelium	GO:0030277	7	0.048
regulation of nitrogen compound metabolic process	GO:0051171	251	0.047
nucleic acid metabolic process	GO:0090304	244	0.047
macromolecule localization	GO:0033036	54	0.047
negative regulation of histone methylation	GO:0031061	1	0.047
cytoskeleton dependent intracellular transport	GO:0030705	10	0.047
positive regulation of cell cycle	GO:0045787	3	0.047
regulation of epithelial cell proliferation	GO:0050678	3	0.046
regulation of cell projection assembly	GO:0060491	4	0.046
muscle structure development	GO:0061061	196	0.046
positive regulation of neural precursor cell proliferation	GO:2000179	1	0.046
pigmentation	GO:0043473	85	0.046
cell migration involved in sprouting angiogenesis	GO:0002042	8	0.046
response to hexose	GO:0009746	3	0.046
muscle cell differentiation	GO:0042692	139	0.046
macromolecule modification	GO:0043412	111	0.045
regulation of canonical wnt signaling pathway	GO:0060828	34	0.045
regulation of cellular component size	GO:0032535	30	0.045
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.045
positive regulation of glucose import	GO:0046326	1	0.045
organelle localization	GO:0051640	49	0.044
cell cycle process	GO:0022402	53	0.044
positive regulation of catalytic activity	GO:0043085	25	0.044
inner ear receptor cell development	GO:0060119	20	0.044
cilium or flagellum dependent cell motility	GO:0001539	4	0.044
protein localization to microtubule cytoskeleton	GO:0072698	1	0.043
intestinal epithelial structure maintenance	GO:0060729	7	0.043
proximal tubule development	GO:0072014	3	0.043
multicellular organismal signaling	GO:0035637	22	0.043
endocardium development	GO:0003157	9	0.043
cartilage development	GO:0051216	96	0.042
positive regulation of cell matrix adhesion	GO:0001954	1	0.042	Mouse
endomembrane system organization	GO:0010256	13	0.042
protein phosphorylation	GO:0006468	47	0.042
axon extension	GO:0048675	45	0.042
nephron development	GO:0072006	31	0.042
ventral spinal cord interneuron differentiation	GO:0021514	12	0.042
striated muscle cell differentiation	GO:0051146	129	0.042
cellular response to endogenous stimulus	GO:0071495	68	0.042	Mouse
camera type eye photoreceptor cell differentiation	GO:0060219	19	0.041
growth	GO:0040007	174	0.041	Mouse
positive regulation of signal transduction	GO:0009967	56	0.041
regulation of biosynthetic process	GO:0009889	250	0.041
nucleic acid templated transcription	GO:0097659	181	0.041
intrinsic apoptotic signaling pathway in response to oxidative stress	GO:0008631	2	0.040
purine nucleotide metabolic process	GO:0006163	27	0.040
mechanosensory lateral line system development	GO:0048881	49	0.040
embryonic skeletal system development	GO:0048706	97	0.040
amino acid transport	GO:0006865	2	0.040
epiboly	GO:0090504	41	0.040
regulation of protein binding	GO:0043393	3	0.040	Mouse
olfactory bulb development	GO:0021772	4	0.040
multi organism cellular process	GO:0044764	2	0.040
regulation of autophagy	GO:0010506	3	0.039
aorta development	GO:0035904	4	0.039
schwann cell differentiation	GO:0014037	9	0.039
establishment or maintenance of monopolar cell polarity	GO:0061339	2	0.039	Fly
mrna processing	GO:0006397	14	0.039
regulation of synapse organization	GO:0050807	3	0.038
cell fate commitment	GO:0045165	99	0.038
biosynthetic process	GO:0009058	294	0.037
urogenital system development	GO:0001655	97	0.037
cell fate specification	GO:0001708	68	0.037
regulation of nucleoside metabolic process	GO:0009118	2	0.037
spermatid differentiation	GO:0048515	2	0.037
regulation of nucleotide catabolic process	GO:0030811	2	0.037
regulation of photoreceptor cell differentiation	GO:0046532	2	0.036
epiboly involved in gastrulation with mouth forming second	GO:0055113	35	0.036
single organism cellular localization	GO:1902580	46	0.036
developmental maturation	GO:0021700	34	0.036
schwann cell development	GO:0014044	9	0.036
cellular component disassembly	GO:0022411	1	0.036
axon guidance	GO:0007411	86	0.035
rostrocaudal neural tube patterning	GO:0021903	29	0.035
immune system process	GO:0002376	241	0.035
glucose import	GO:0046323	2	0.035
renal system process	GO:0003014	14	0.035
detection of abiotic stimulus	GO:0009582	24	0.035
guanosine containing compound metabolic process	GO:1901068	4	0.035
auditory receptor cell fate commitment	GO:0009912	4	0.035
ion transport	GO:0006811	114	0.035
dorsal ventral pattern formation	GO:0009953	125	0.034
rna processing	GO:0006396	25	0.034
central nervous system neuron differentiation	GO:0021953	74	0.034
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	42	0.034
cellular response to nutrient levels	GO:0031669	2	0.033
cell matrix adhesion	GO:0007160	4	0.033	Mouse
developmental cell growth	GO:0048588	52	0.033
organonitrogen compound metabolic process	GO:1901564	74	0.033
regulation of myotube differentiation	GO:0010830	2	0.033
regulation of purine nucleotide catabolic process	GO:0033121	2	0.033
canonical wnt signaling pathway	GO:0060070	48	0.033
ventral spinal cord interneuron fate commitment	GO:0060579	3	0.033
negative regulation of cell death	GO:0060548	60	0.032
positive regulation of catabolic process	GO:0009896	4	0.032
exocrine pancreas development	GO:0031017	28	0.032
fertilization	GO:0009566	3	0.031
positive regulation of stem cell proliferation	GO:2000648	1	0.031
negative regulation of programmed cell death	GO:0043069	58	0.031
negative regulation of macromolecule metabolic process	GO:0010605	76	0.031
response to monosaccharide	GO:0034284	3	0.031
response to glucose	GO:0009749	3	0.031
cellular response to hypoxia	GO:0071456	1	0.031
aromatic compound biosynthetic process	GO:0019438	217	0.031
regulation of eye photoreceptor cell development	GO:0042478	2	0.031
ventral spinal cord interneuron specification	GO:0021521	3	0.030
mitotic nuclear division	GO:0007067	18	0.030
gamete generation	GO:0007276	33	0.030
skeletal system development	GO:0001501	181	0.030
posterior lateral line development	GO:0048916	38	0.030
negative regulation of apoptotic process	GO:0043066	55	0.029
regulation of oligodendrocyte differentiation	GO:0048713	1	0.029
mrna 3 end processing	GO:0031124	2	0.029
positive regulation of nervous system development	GO:0051962	25	0.029
positive regulation of cellular process	GO:0048522	201	0.029
tissue migration	GO:0090130	37	0.029	Mouse
regulation of locomotion	GO:0040012	55	0.029	Mouse
modification of morphology or physiology of other organism	GO:0035821	4	0.029
tissue regeneration	GO:0042246	74	0.029
metencephalon development	GO:0022037	27	0.029
phagocytosis	GO:0006909	3	0.029
regulation of nucleic acid templated transcription	GO:1903506	213	0.029
glial cell development	GO:0021782	20	0.029
cellular response to light stimulus	GO:0071482	4	0.029
negative regulation of multicellular organismal process	GO:0051241	69	0.028
negative regulation of nitrogen compound metabolic process	GO:0051172	59	0.028
photoreceptor cell development	GO:0042461	40	0.028	Fly
multicellular organism growth	GO:0035264	4	0.028
response to organic substance	GO:0010033	153	0.028	Mouse
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules	GO:0016339	2	0.028
appendage morphogenesis	GO:0035107	56	0.028
regulation of gtpase activity	GO:0043087	2	0.028
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.028
regulation of cell activation	GO:0050865	1	0.028
positive regulation of secretion by cell	GO:1903532	1	0.028
immunoglobulin mediated immune response	GO:0016064	3	0.028
regulation of stem cell proliferation	GO:0072091	2	0.028
regulation of cellular component biogenesis	GO:0044087	12	0.028	Mouse
odontogenesis of dentin containing tooth	GO:0042475	1	0.027
cell differentiation in spinal cord	GO:0021515	40	0.027
purine ribonucleotide metabolic process	GO:0009150	27	0.027
detection of external stimulus	GO:0009581	24	0.027
establishment of organelle localization	GO:0051656	45	0.026
lateral line development	GO:0048882	66	0.026
optokinetic behavior	GO:0007634	9	0.026
hypothalamus cell differentiation	GO:0021979	4	0.026
muscle cell development	GO:0055001	115	0.026
epithelial cell migration	GO:0010631	25	0.026	Mouse
positive regulation of multicellular organismal process	GO:0051240	52	0.025	Mouse
regulation of peptidyl tyrosine phosphorylation	GO:0050730	1	0.025
organophosphate metabolic process	GO:0019637	37	0.025
positive regulation of protein complex assembly	GO:0031334	2	0.025
regulation of neural precursor cell proliferation	GO:2000177	3	0.025
sensory system development	GO:0048880	76	0.025
embryonic limb morphogenesis	GO:0030326	2	0.025
pancreas development	GO:0031016	84	0.025
regulation of mrna catabolic process	GO:0061013	3	0.025
convergent extension	GO:0060026	118	0.024
carbohydrate derivative metabolic process	GO:1901135	61	0.024
positive regulation of nucleotide catabolic process	GO:0030813	1	0.024
regulation of multicellular organism growth	GO:0040014	4	0.024
positive regulation of notch signaling pathway	GO:0045747	3	0.024
cellular process involved in reproduction in multicellular organism	GO:0022412	28	0.024
establishment of synaptic vesicle localization	GO:0097480	1	0.024
organic cyclic compound catabolic process	GO:1901361	15	0.024
regulation of blood vessel endothelial cell migration	GO:0043535	5	0.024
positive regulation of gtp catabolic process	GO:0033126	1	0.024
establishment of spindle orientation	GO:0051294	10	0.024
centrosome cycle	GO:0007098	1	0.024
establishment of melanosome localization	GO:0032401	19	0.024
pore complex assembly	GO:0046931	2	0.024

epb41l5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
eye disease	DOID:5614	0.030
disease of anatomical entity	DOID:7	0.030
sensory system disease	DOID:0050155	0.030
retinal disease	DOID:5679	0.030
nervous system disease	DOID:863	0.030
eye and adnexa disease	DOID:1492	0.030
physical disorder	DOID:0080015	0.029

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