Danio rerio

0 known processes

tjp2a

tight junction protein 2a (zona occludens 2)

(Aliases: tjp2.1,wu:fb10a11,zo-2.1)

tjp2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell motilityGO:00488702440.380
localization of cellGO:00516742440.232
morphogenesis of an epitheliumGO:00020093330.223
Fly
heart loopingGO:0001947940.139
regulation of multicellular organismal processGO:00512392770.136
Fly
cellular component movementGO:00069283350.120
determination of left right symmetryGO:00073681790.094
protein modification processGO:00362111000.087
synaptic growth at neuromuscular junctionGO:005112420.086
anterior posterior pattern specificationGO:00099521520.077
cell surface receptor signaling pathwayGO:00071663250.076
cellular component biogenesisGO:00440851780.075
Fly
embryonic heart tube developmentGO:00350501330.073
protein polymerizationGO:005125840.073
mesenchyme developmentGO:00604851270.069
regulation of synapse assemblyGO:005196330.069
positive regulation of protein complex assemblyGO:003133420.069
regulation of synapse organizationGO:005080730.067
regulation of signalingGO:00230512350.065
actin filament based movementGO:003004810.064
cardiac chamber developmentGO:0003205190.063
cellular protein modification processGO:00064641000.062
specification of symmetryGO:00097992040.062
sensory organ developmentGO:00074233930.059
Fly
cellular response to external stimulusGO:007149620.059
determination of heart left right asymmetryGO:00613711170.059
cell migrationGO:00164772370.058
negative regulation of stem cell differentiationGO:200073720.058
regulation of establishment of protein localizationGO:007020140.057
regulation of intracellular protein transportGO:003315730.057
regulation of cell communicationGO:00106462320.057
ameboidal type cell migrationGO:00016671430.055
cellular component assemblyGO:00226071700.054
Fly
sensory perceptionGO:0007600390.054
regulation of protein import into nucleusGO:004230620.054
heart morphogenesisGO:00030071560.053
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.053
cell projection organizationGO:00300302840.052
Fly
actin polymerization or depolymerizationGO:000815420.052
central nervous system developmentGO:00074173870.052
desmosome organizationGO:000293430.052
negative regulation of kinase activityGO:003367340.050
release of sequestered calcium ion into cytosolGO:005120930.048
single organism nuclear importGO:190259330.048
regulation of response to oxidative stressGO:190288220.048
system processGO:00030081850.048
epithelial tube morphogenesisGO:00605621480.048
Fly
developmental growthGO:00485891660.046
cellular response to radiationGO:007147840.046
regulation of embryonic developmentGO:0045995470.045
Fly
cellular response to extracellular stimulusGO:003166820.045
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.045
positive regulation of transportGO:005105020.045
epithelial cell morphogenesisGO:000338220.044
head developmentGO:00603223030.043
cell proliferationGO:0008283800.043
epithelial cell differentiationGO:00308551160.043
embryonic heart tube morphogenesisGO:00031431080.042
regulation of multicellular organismal developmentGO:20000262230.042
Fly
regulation of muscle contractionGO:000693730.042
regulation of signal transductionGO:00099662250.042
regulation of synaptic growth at neuromuscular junctionGO:000858210.041
negative regulation of cellular processGO:00485232830.041
renal system developmentGO:0072001940.041
digestive tract developmentGO:00485652650.041
adherens junction organizationGO:003433240.041
Fly
cellular macromolecule metabolic processGO:00442603910.041
regulation of cell motilityGO:2000145460.041
wnt signaling pathwayGO:0016055800.040
actin filament polymerizationGO:003004120.040
blood vessel developmentGO:00015682460.040
adult behaviorGO:003053420.040
kidney developmentGO:0001822920.040
regulation of anatomical structure morphogenesisGO:00226031300.040
Fly
negative regulation of sequestering of calcium ionGO:005128340.039
regulation of blood pressureGO:000821710.039
response to abiotic stimulusGO:00096281220.039
female sex differentiationGO:004666040.039
multicellular organism growthGO:003526440.038
protein targeting to nucleusGO:004474430.038
negative regulation of biological processGO:00485193040.038
regulation of wnt signaling pathwayGO:0030111530.038
nuclear migrationGO:000709730.038
carboxylic acid metabolic processGO:0019752220.037
glucose importGO:004632320.037
regulation of cytoplasmic transportGO:190364940.037
regulation of vasculature developmentGO:1901342330.037
odontogenesis of dentin containing toothGO:004247510.036
stem cell proliferationGO:007208940.035
regulation of mrna processingGO:005068430.035
positive regulation of cellular component biogenesisGO:004408930.035
negative regulation of protein phosphorylationGO:000193340.034
regionalizationGO:00030022740.034
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.034
locomotor rhythmGO:004547530.034
response to stressGO:00069502630.034
macromolecule modificationGO:00434121110.033
regulation of glucose transportGO:001082710.033
locomotionGO:00400113130.033
eye developmentGO:00016542770.032
Fly
regulation of circadian rhythmGO:004275240.032
regulation of protein transportGO:005122330.032
calcium ion transport into cytosolGO:006040230.031
oxoacid metabolic processGO:0043436310.031
ras protein signal transductionGO:000726570.031
macromolecular complex assemblyGO:0065003350.031
determination of bilateral symmetryGO:00098552040.031
cellular ketone metabolic processGO:0042180110.031
regulation of cell migrationGO:0030334400.030
nuclear transportGO:005116940.030
regulation of response to stimulusGO:00485832690.030
organic acid metabolic processGO:0006082310.030
macroautophagyGO:001623610.030
regulation of tube sizeGO:003515020.029
single organism organelle organizationGO:19025891990.029
cellular response to starvationGO:000926710.029
segmentationGO:0035282970.029
cellular carbohydrate metabolic processGO:004426240.029
regulation of sequestering of calcium ionGO:005128240.029
regulation of macromolecule metabolic processGO:00602553170.029
response to decreased oxygen levelsGO:0036293250.028
digestive system developmentGO:00551232890.028
negative regulation of multicellular organismal processGO:0051241690.028
stem cell differentiationGO:00488631170.028
detection of external stimulusGO:0009581240.028
heterocycle biosynthetic processGO:00181302150.027
angiogenesisGO:00015251580.027
sequestering of calcium ionGO:005120830.027
regulation of protein localization to nucleusGO:190018020.027
nucleocytoplasmic transportGO:000691340.027
regulation of endocrine processGO:004406020.027
regulation of wound healingGO:006104120.027
vasculature developmentGO:00019442780.026
cellular localizationGO:0051641970.026
regulation of reproductive processGO:200024140.026
regulation of cellular metabolic processGO:00313233200.026
response to endogenous stimulusGO:0009719830.026
cellular response to light stimulusGO:007148240.026
leukocyte chemotaxisGO:0030595120.026
urogenital system developmentGO:0001655970.026
regulation of nucleocytoplasmic transportGO:004682220.025
protein import into nucleusGO:000660630.025
regulation of stem cell proliferationGO:007209120.025
positive regulation of cytokine productionGO:000181920.025
response to chemicalGO:00422213200.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.025
maintenance of locationGO:005123540.025
cellular protein metabolic processGO:00442671290.025
nuclear importGO:005117030.024
regulation of developmental processGO:00507932470.024
Fly
ribosomal small subunit biogenesisGO:004227420.024
biological adhesionGO:0022610400.024
Fly
regulation of membrane potentialGO:0042391230.024
detection of abiotic stimulusGO:0009582240.024
neuroblast proliferationGO:000740520.023
regulation of reactive oxygen species metabolic processGO:200037720.023
regulation of striated muscle contractionGO:000694220.023
single organism transportGO:00447652060.023
regulation of cellular protein metabolic processGO:0032268520.023
positive regulation of small gtpase mediated signal transductionGO:005105710.023
multicellular organismal metabolic processGO:004423620.023
regulation of cytokine productionGO:000181730.023
determination of dorsal ventral asymmetryGO:0048262340.022
circulatory system processGO:0003013870.022
agingGO:000756820.022
embryonic organ morphogenesisGO:00485622740.022
regulation of synapse structure and activityGO:005080350.022
nucleobase containing compound metabolic processGO:00061392740.022
taxisGO:00423301090.022
establishment of protein localization to organelleGO:007259440.022
neural crest cell migrationGO:0001755420.022
negative regulation of cell deathGO:0060548600.022
protein importGO:001703830.021
autophagyGO:000691440.021
regulation of stem cell differentiationGO:200073640.021
regulation of mrna catabolic processGO:006101330.021
growthGO:00400071740.021
cell morphogenesis involved in differentiationGO:00009041950.021
regulation of cellular carbohydrate metabolic processGO:001067540.021
dorsal motor nucleus of vagus nerve developmentGO:002174440.021
negative regulation of protein kinase activityGO:000646940.021
cell projection morphogenesisGO:00488582440.021
Fly
larval developmentGO:000216420.021
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.020
regulation of carbohydrate metabolic processGO:000610940.020
establishment of endothelial barrierGO:006102830.020
regulation of receptor mediated endocytosisGO:004825940.020
action potentialGO:0001508190.020
cell cell junction organizationGO:0045216100.020
Fly
positive regulation of protein polymerizationGO:003227320.020
developmental programmed cell deathGO:001062340.020
positive regulation of canonical wnt signaling pathwayGO:009026340.020
cellular modified amino acid metabolic processGO:000657530.020
cognitionGO:005089010.020
ventricular cardiac muscle tissue morphogenesisGO:005501020.020
protein metabolic processGO:00195381830.019
regulation of glucose importGO:004632410.019
regulation of multicellular organism growthGO:004001440.019
embryonic organ developmentGO:00485683810.019
response to xenobiotic stimulusGO:0009410450.018
protein complex disassemblyGO:004324110.018
cellular response to nutrient levelsGO:003166920.018
positive regulation of cytosolic calcium ion concentrationGO:000720440.018
positive regulation of epithelial cell migrationGO:001063420.018
cytosolic calcium ion transportGO:006040130.018
cellular response to hypoxiaGO:007145610.018
regulation of gene expressionGO:00104682650.017
cellular component disassemblyGO:002241110.017
organelle organizationGO:00069962270.017
cellular transition metal ion homeostasisGO:004691630.017
aorta developmentGO:003590440.017
ventricular cardiac muscle tissue developmentGO:000322930.017
response to drugGO:004249330.017
neural crest cell developmentGO:0014032620.017
response to external stimulusGO:00096052640.017
regulation of cellular component movementGO:0051270550.017
regulation of blood vessel sizeGO:005088020.016
cellular amine metabolic processGO:004410620.016
establishment of nucleus localizationGO:004002370.016
blood vessel endothelial cell migrationGO:0043534180.016
positive regulation of cytoskeleton organizationGO:005149530.016
multi organism processGO:00517041340.016
positive regulation of ras protein signal transductionGO:004657910.016
protein dephosphorylationGO:000647030.016
tube morphogenesisGO:00352393490.016
Fly
water homeostasisGO:003010440.016
protein complex biogenesisGO:0070271300.016
protein localization to nucleusGO:003450430.016
regulation of blood coagulationGO:003019310.016
regulation of localizationGO:00328791040.016
negative regulation of cell differentiationGO:0045596460.016
desmosome assemblyGO:000215920.016
signal transductionGO:00071654550.016
amine metabolic processGO:000930820.016
regulation of anterior head developmentGO:200074220.015
regulation of cell cell adhesionGO:0022407130.015
aromatic compound biosynthetic processGO:00194382170.015
sequestering of metal ionGO:005123830.015
cell cell junction maintenanceGO:004521710.015
myotube differentiationGO:0014902450.015
regulation of blood circulationGO:1903522320.015
regulation of establishment or maintenance of cell polarityGO:003287820.015
macromolecular complex disassemblyGO:003298410.015
response to organic cyclic compoundGO:0014070510.015
regulation of cell differentiationGO:00455951420.015
monoamine transportGO:001584410.015
glomerular filtrationGO:000309460.014
response to carbohydrateGO:000974330.014
pigmentationGO:0043473850.014
tissue migrationGO:0090130370.014
renal filtrationGO:0097205100.014
muscle attachmentGO:001620390.014
innervationGO:006038430.014
adherens junction assemblyGO:003433310.014
Fly
intracellular transportGO:0046907320.014
phosphorus metabolic processGO:00067931090.014
endocrine processGO:005088620.014
cell morphogenesisGO:00009022890.014
Fly
specification of organ identityGO:001009220.014
lymph vessel developmentGO:0001945270.014
regulation of organ morphogenesisGO:2000027350.014
regulation of cellular response to oxidative stressGO:190040720.014
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.014
notochord developmentGO:0030903540.014
regulation of cell projection assemblyGO:006049140.014
regulation of cellular amino acid metabolic processGO:000652100.014
detection of stimulusGO:0051606290.014
stem cell maintenanceGO:001982740.014
heart joggingGO:0003146400.013
adherens junction maintenanceGO:003433420.013
establishment of organelle localizationGO:0051656450.013
muscle organ developmentGO:00075171010.013
macromolecular complex subunit organizationGO:0043933740.013
chemosensory behaviorGO:000763510.013
response to oxygen levelsGO:0070482250.013
lipid storageGO:001991510.013
cardiac cell fate commitmentGO:006091110.013
phosphate containing compound metabolic processGO:00067961080.013
protein phosphorylationGO:0006468470.013
leukocyte proliferationGO:007066110.013
stem cell developmentGO:0048864820.013
muscle structure developmentGO:00610611960.013
fin developmentGO:0033333770.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.013
regulation of angiogenesisGO:0045765260.013
rna metabolic processGO:00160702190.013
regulation of epithelial cell proliferationGO:005067830.013
immune system developmentGO:00025201910.013
rna 3 end processingGO:003112320.013
organic substance transportGO:0071702580.013
endocrine hormone secretionGO:006098620.013
regulation of protein complex assemblyGO:004325430.012
smooth muscle contractionGO:000693920.012
regulation of hemostasisGO:190004610.012
single organism cell adhesionGO:0098602290.012
Fly
regulation of metal ion transportGO:001095940.012
blood circulationGO:0008015870.012
protein k48 linked ubiquitinationGO:007093610.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
actin filament based processGO:0030029640.012
regulation of epithelial to mesenchymal transitionGO:001071730.012
multi organism reproductive processGO:0044703360.012
regulation of wnt signaling pathway involved in heart developmentGO:000330720.012
regulation of epithelial cell migrationGO:001063250.012
organonitrogen compound metabolic processGO:1901564740.012
defense response to fungusGO:005083220.012
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.012
mitochondrion organizationGO:000700540.012
gastrulationGO:00073692080.012
cell cell signaling involved in cell fate commitmentGO:0045168120.012
Fly
chordate embryonic developmentGO:00430092710.012
positive regulation of blood circulationGO:190352420.012
organelle localizationGO:0051640490.012
small molecule metabolic processGO:0044281770.012
regulation of phospholipase c activityGO:190027410.012
gene expressionGO:00104672520.012
negative regulation of tor signalingGO:003200720.012
intracellular signal transductionGO:0035556850.012
regulation of cell deathGO:00109411030.012
regulation of cell projection organizationGO:0031344440.011
regulation of cellular amine metabolic processGO:003323800.011
chondrocyte developmentGO:000206340.011
regulation of rho protein signal transductionGO:003502320.011
cell deathGO:00082191210.011
locomotory behaviorGO:0007626340.011
cellular response to endogenous stimulusGO:0071495680.011
transcription from rna polymerase ii promoterGO:0006366800.011
meiotic spindle organizationGO:000021210.011
cellular aromatic compound metabolic processGO:00067252950.011
cellular component maintenanceGO:004395430.011
behaviorGO:0007610740.011
transportGO:00068102200.011
somite developmentGO:0061053960.011
granulocyte chemotaxisGO:0071621110.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
negative regulation of epithelial cell proliferationGO:005068010.011
regulation of systemic arterial blood pressureGO:000307310.011
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.011
establishment of localizationGO:00512342440.011
entrainment of circadian clockGO:000964920.011
leukocyte migrationGO:0050900150.011
specification of axis polarityGO:006500140.011
regulation of heart growthGO:006042020.011
positive regulation of secretion by cellGO:190353210.011
positive regulation of myeloid cell differentiationGO:004563920.011
response to nutrientGO:000758430.011
regulation of myotube differentiationGO:001083020.011
regulation of coagulationGO:005081820.010
morphogenesis of an epithelial sheetGO:0002011490.010
positive regulation of jnk cascadeGO:004633030.010
regulation of cell shapeGO:000836010.010
Fly
zymogen activationGO:003163830.010
regulation of organ growthGO:004662030.010
single organism localizationGO:19025782250.010
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.010
response to organic substanceGO:00100331530.010
cytoskeleton organizationGO:0007010960.010
positive regulation of multicellular organismal processGO:0051240520.010
negative regulation of biosynthetic processGO:0009890550.010
fertilizationGO:000956630.010
lymphangiogenesisGO:0001946250.010
cardiac atrium developmentGO:000323040.010
regulation of primary metabolic processGO:00800903110.010
neural crest cell differentiationGO:0014033720.010

tjp2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.312
disease of anatomical entityDOID:700.312
Human
muscle tissue diseaseDOID:6600.104
musculoskeletal system diseaseDOID:1700.104
myopathyDOID:42300.104
muscular diseaseDOID:008000000.104
intrinsic cardiomyopathyDOID:006003600.104
cardiomyopathyDOID:005070000.104
heart diseaseDOID:11400.104
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
cancerDOID:16200.012