Danio rerio

0 known processes

tjp2b

tight junction protein 2b (zona occludens 2)

(Aliases: zgc:92094,wu:fb62b09)

tjp2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chordate embryonic developmentGO:00430092710.488
central nervous system developmentGO:00074173870.312
nuclear transportGO:005116940.247
signal transductionGO:00071654550.194
lipid storageGO:001991510.177
larval developmentGO:000216420.176
negative regulation of cellular processGO:00485232830.175
heart developmentGO:00075073130.174
regulation of signal transductionGO:00099662250.166
head developmentGO:00603223030.159
determination of left right symmetryGO:00073681790.157
adherens junction organizationGO:003433240.150
sensory organ developmentGO:00074233930.145
regulation of cell communicationGO:00106462320.140
maintenance of locationGO:005123540.138
cell projection organizationGO:00300302840.137
digestive tract developmentGO:00485652650.129
negative regulation of biological processGO:00485193040.121
regulation of primary metabolic processGO:00800903110.120
chemical homeostasisGO:0048878490.116
Zebrafish
heterocycle metabolic processGO:00464832900.102
nucleocytoplasmic transportGO:000691340.101
localization of cellGO:00516742440.097
regulation of intracellular protein transportGO:003315730.097
negative regulation of protein phosphorylationGO:000193340.097
regulation of protein transportGO:005122330.094
regulation of metabolic processGO:00192223590.093
determination of bilateral symmetryGO:00098552040.091
regulation of response to stimulusGO:00485832690.089
embryonic organ developmentGO:00485683810.087
regulation of reproductive processGO:200024140.085
somitogenesisGO:0001756870.085
organic acid metabolic processGO:0006082310.083
cellular component morphogenesisGO:00329893360.082
tube morphogenesisGO:00352393490.082
single organism nuclear importGO:190259330.081
regulation of biological qualityGO:00650082630.080
Zebrafish
agingGO:000756820.080
digestive system developmentGO:00551232890.080
cell surface receptor signaling pathwayGO:00071663250.078
protein import into nucleusGO:000660630.077
positive regulation of metabolic processGO:00098931080.074
nuclear migrationGO:000709730.073
cellular component biogenesisGO:00440851780.072
regulation of signalingGO:00230512350.072
somite developmentGO:0061053960.072
negative regulation of protein kinase activityGO:000646940.071
negative regulation of response to stimulusGO:00485851040.067
brain developmentGO:00074202930.066
establishment of protein localization to organelleGO:007259440.065
organonitrogen compound metabolic processGO:1901564740.065
oxoacid metabolic processGO:0043436310.064
small molecule metabolic processGO:0044281770.064
cellular macromolecule metabolic processGO:00442603910.064
protein targeting to nucleusGO:004474430.064
organic cyclic compound biosynthetic processGO:19013622230.063
carboxylic acid metabolic processGO:0019752220.063
regulation of developmental processGO:00507932470.062
protein metabolic processGO:00195381830.061
morphogenesis of an epitheliumGO:00020093330.060
cell migrationGO:00164772370.060
regulation of cytoplasmic transportGO:190364940.059
negative regulation of cell communicationGO:0010648960.058
mesenchyme developmentGO:00604851270.058
positive regulation of cellular processGO:00485222010.057
regionalizationGO:00030022740.056
regulation of heart growthGO:006042020.056
embryo development ending in birth or egg hatchingGO:00097922710.056
positive regulation of biological processGO:00485182530.055
regulation of gtp catabolic processGO:003312420.055
system processGO:00030081850.055
regulation of cellular amine metabolic processGO:003323800.054
cellular aromatic compound metabolic processGO:00067252950.054
response to external stimulusGO:00096052640.053
multicellular organism growthGO:003526440.053
cell morphogenesisGO:00009022890.053
establishment of localizationGO:00512342440.053
embryonic organ morphogenesisGO:00485622740.052
protein localization to plasma membraneGO:007265910.051
regulation of protein localization to nucleusGO:190018020.051
cellular ketone metabolic processGO:0042180110.051
cellular component movementGO:00069283350.051
regulation of multicellular organismal developmentGO:20000262230.050
regulation of multicellular organism growthGO:004001440.050
regulation of cellular metabolic processGO:00313233200.050
cellular biosynthetic processGO:00442492860.049
cell adhesionGO:0007155400.048
nephron morphogenesisGO:007202820.048
cognitionGO:005089010.048
neurotransmitter transportGO:000683620.048
regulation of nucleotide catabolic processGO:003081120.046
cellular protein catabolic processGO:004425740.046
cell proliferationGO:0008283800.045
determination of heart left right asymmetryGO:00613711170.045
amine metabolic processGO:000930820.045
cellular component assemblyGO:00226071700.045
lateral inhibitionGO:004633110.045
cellular nitrogen compound metabolic processGO:00346412900.043
organelle organizationGO:00069962270.043
peptide metabolic processGO:000651810.043
neuron projection morphogenesisGO:00488121610.043
synaptic growth at neuromuscular junctionGO:005112420.042
cellular amine metabolic processGO:004410620.042
segmentationGO:0035282970.042
fertilizationGO:000956630.042
single organism transportGO:00447652060.042
regulation of protein ubiquitinationGO:003139630.041
regulation of nucleoside metabolic processGO:000911820.041
regulation of cardiac muscle tissue developmentGO:005502410.041
protein importGO:001703830.041
regulation of protein import into nucleusGO:004230620.040
negative regulation of protein transportGO:005122430.040
cellular component assembly involved in morphogenesisGO:00109271070.040
phagocytosisGO:000690930.040
protein localization to nucleusGO:003450430.040
regulation of organ growthGO:004662030.040
cellular response to radiationGO:007147840.040
gastrulationGO:00073692080.038
regulation of nucleocytoplasmic transportGO:004682220.038
transcription from rna polymerase ii promoterGO:0006366800.038
negative regulation of signal transductionGO:0009968940.037
anterior posterior pattern specificationGO:00099521520.037
lateral line developmentGO:0048882660.037
gtp metabolic processGO:004603940.037
single organism metabolic processGO:00447102170.037
ameboidal type cell migrationGO:00016671430.036
regulation of localizationGO:00328791040.036
digestive tract morphogenesisGO:00485462310.036
nucleobase containing compound metabolic processGO:00061392740.036
regulation of purine nucleotide catabolic processGO:003312120.036
guanosine containing compound catabolic processGO:190106920.035
cellular component disassemblyGO:002241110.034
cellular response to stressGO:0033554620.034
negative regulation of kinase activityGO:003367340.034
muscle cell differentiationGO:00426921390.034
blood circulationGO:0008015870.034
single organism localizationGO:19025782250.033
adult behaviorGO:003053420.033
regulation of molecular functionGO:0065009700.033
positive regulation of nucleoside metabolic processGO:004597910.033
enzyme linked receptor protein signaling pathwayGO:00071671060.032
eye developmentGO:00016542770.032
cellular protein metabolic processGO:00442671290.032
negative regulation of multicellular organismal processGO:0051241690.032
transportGO:00068102200.031
guanosine containing compound metabolic processGO:190106840.030
mitotic dna integrity checkpointGO:004477440.030
regulation of establishment of protein localizationGO:007020140.030
modulation by virus of host morphology or physiologyGO:001904810.030
regulation of cell shapeGO:000836010.030
negative regulation of signalingGO:0023057960.030
liver developmentGO:0001889960.030
regulation of gene expressionGO:00104682650.030
negative regulation of molecular functionGO:0044092230.029
gland developmentGO:00487321430.029
regulation of locomotionGO:0040012550.029
regulation of extrinsic apoptotic signaling pathwayGO:200123630.029
cell morphogenesis involved in differentiationGO:00009041950.029
heart loopingGO:0001947940.029
regulation of dna replicationGO:000627530.029
nitrogen compound metabolic processGO:00068073190.029
cilium morphogenesisGO:0060271850.029
heart morphogenesisGO:00030071560.029
adherens junction assemblyGO:003433310.028
regulation of protein targetingGO:190353320.028
cellular amino acid metabolic processGO:000652070.028
regulation of nervous system developmentGO:0051960900.028
cellular lipid metabolic processGO:0044255360.028
nuclear exportGO:005116810.028
negative regulation of intracellular protein transportGO:009031730.028
pancreas developmentGO:0031016840.027
regulation of response to oxidative stressGO:190288220.027
convergent extension involved in gastrulationGO:0060027710.027
regulation of epithelial cell proliferationGO:005067830.026
muscle structure developmentGO:00610611960.026
cation transportGO:0006812810.026
wnt signaling pathwayGO:0016055800.026
regulation of embryonic developmentGO:0045995470.026
regulation of cellular ketone metabolic processGO:001056570.026
organelle assemblyGO:00709251100.025
proteolysis involved in cellular protein catabolic processGO:005160330.025
developmental growth involved in morphogenesisGO:0060560860.025
forebrain developmentGO:0030900960.025
neuron differentiationGO:00301823530.025
ion transportGO:00068111140.025
regulation of protein modification by small protein conjugation or removalGO:190332030.025
gtp catabolic processGO:000618420.025
negative regulation of protein import into nucleusGO:004230820.025
detection of abiotic stimulusGO:0009582240.025
phosphate containing compound metabolic processGO:00067961080.025
cell motilityGO:00488702440.025
cellular response to chemical stimulusGO:00708871570.024
germ line stem cell divisionGO:004207810.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
negative regulation of cytoplasmic transportGO:190365020.024
negative regulation of developmental processGO:0051093650.024
mitochondrion organizationGO:000700540.024
cellular response to hypoxiaGO:007145610.024
regulation of macromolecule metabolic processGO:00602553170.024
single organism organelle organizationGO:19025891990.024
regulation of nucleobase containing compound metabolic processGO:00192192500.024
cell substrate adhesionGO:003158940.024
positive regulation of cellular catabolic processGO:003133130.024
epithelial cell morphogenesisGO:000338220.024
embryonic cranial skeleton morphogenesisGO:0048701900.024
nuclear importGO:005117030.024
regulation of anatomical structure morphogenesisGO:00226031300.023
notochord developmentGO:0030903540.023
nephron epithelium morphogenesisGO:007208810.023
negative regulation of intracellular transportGO:003238730.023
cellular response to external stimulusGO:007149620.023
actin filament based processGO:0030029640.023
regulation of reactive oxygen species metabolic processGO:200037720.023
modification dependent macromolecule catabolic processGO:004363230.023
neurological system processGO:0050877620.023
extracellular matrix organizationGO:0030198270.023
regulation of synapse assemblyGO:005196330.023
regulation of catalytic activityGO:0050790550.023
deathGO:00162651210.023
phosphorylationGO:0016310690.023
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.023
regulation of cellular amino acid metabolic processGO:000652100.022
regulation of transcription dna templatedGO:00063552130.022
regulation of cell migrationGO:0030334400.022
nucleobase containing compound biosynthetic processGO:00346542050.022
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
regulation of apoptotic processGO:0042981980.022
appendage developmentGO:0048736800.022
pronuclear migrationGO:003504610.022
regulation of cell matrix adhesionGO:000195210.022
ubiquitin dependent protein catabolic processGO:000651130.022
regulation of erk1 and erk2 cascadeGO:007037240.022
action potentialGO:0001508190.022
regulation of peptidase activityGO:0052547230.022
regulation of cellular component movementGO:0051270550.022
organic substance biosynthetic processGO:19015762890.022
renal tubule morphogenesisGO:006133310.021
cell deathGO:00082191210.021
photoreceptor cell differentiationGO:0046530550.021
extracellular structure organizationGO:0043062270.021
positive regulation of cellular component biogenesisGO:004408930.021
positive regulation of gtpase activityGO:004354710.021
cardiac muscle tissue developmentGO:0048738480.021
intracellular receptor signaling pathwayGO:0030522300.021
chemosensory behaviorGO:000763510.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.020
regulation of membrane potentialGO:0042391230.020
intracellular signal transductionGO:0035556850.020
positive regulation of transportGO:005105020.020
protein localizationGO:0008104400.020
cellular macromolecule biosynthetic processGO:00346452240.020
single organism intracellular transportGO:1902582250.020
generation of neuronsGO:00486993850.020
regulation of gtpase activityGO:004308720.020
modification of morphology or physiology of other organismGO:003582140.020
positive regulation of purine nucleotide catabolic processGO:003312310.020
homeostatic processGO:00425921420.019
Zebrafish
meiotic nuclear divisionGO:000712640.019
heterocycle biosynthetic processGO:00181302150.019
cell cell junction organizationGO:0045216100.019
negative regulation of macromolecule metabolic processGO:0010605760.019
locomotionGO:00400113130.019
cell projection morphogenesisGO:00488582440.019
positive regulation of stress activated mapk cascadeGO:003287430.019
dorsal ventral pattern formationGO:00099531250.019
regulation of circadian rhythmGO:004275240.019
actin cytoskeleton organizationGO:0030036630.019
cardiac atrium developmentGO:000323040.019
positive regulation of macromolecule metabolic processGO:0010604930.019
forebrain regionalizationGO:002187140.019
response to nutrientGO:000758430.019
negative regulation of nucleic acid templated transcriptionGO:1903507450.018
regulation of developmental growthGO:0048638380.018
phagocytosis engulfmentGO:000691110.018
multicellular organismal signalingGO:0035637220.018
oxidation reduction processGO:0055114410.018
regulation of rho protein signal transductionGO:003502320.018
response to stressGO:00069502630.018
cell cycle arrestGO:000705010.018
locomotor rhythmGO:004547530.018
regulation of macromolecule biosynthetic processGO:00105562250.018
cell substrate junction assemblyGO:000704420.018
axon guidanceGO:0007411860.018
establishment of localization in cellGO:0051649770.018
actin mediated cell contractionGO:007025210.018
positive regulation of cellular metabolic processGO:0031325940.018
embryonic viscerocranium morphogenesisGO:0048703520.018
convergent extensionGO:00600261180.017
axon ensheathmentGO:0008366180.017
neuron developmentGO:00486662620.017
adherens junction maintenanceGO:003433420.017
lateral line system developmentGO:0048925760.017
multi organism cellular processGO:004476420.017
stem cell maintenanceGO:001982740.017
sensory organ morphogenesisGO:00905962000.017
phosphorus metabolic processGO:00067931090.017
regulation of cell developmentGO:00602841000.017
embryonic heart tube developmentGO:00350501330.017
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.017
oocyte maturationGO:000155640.017
negative regulation of protein localization to nucleusGO:190018120.017
cellular response to light stimulusGO:007148240.017
positive regulation of translationGO:004572710.016
cell projection assemblyGO:0030031640.016
positive regulation of catabolic processGO:000989640.016
response to drugGO:004249330.016
positive regulation of nucleotide catabolic processGO:003081310.016
regulation of tube sizeGO:003515020.016
protein heterooligomerizationGO:005129110.016
regulation of synapse organizationGO:005080730.016
cilium assemblyGO:0042384580.016
regulation of metal ion transportGO:001095940.016
lipid metabolic processGO:0006629520.016
aromatic compound biosynthetic processGO:00194382170.016
entrainment of circadian clockGO:000964920.016
regulation of response to biotic stimulusGO:000283120.016
positive regulation of developmental processGO:0051094500.016
regulation of wnt signaling pathwayGO:0030111530.016
peptide transportGO:001583310.016
sensory perceptionGO:0007600390.016
regulation of cellular carbohydrate metabolic processGO:001067540.016
regulation of cellular response to oxidative stressGO:190040720.016
carbohydrate homeostasisGO:003350010.015
nephron tubule morphogenesisGO:007207810.015
peptidyl serine phosphorylationGO:001810510.015
macromolecular complex disassemblyGO:003298410.015
sensory system developmentGO:0048880760.015
hematopoietic progenitor cell differentiationGO:0002244230.015
negative regulation of metabolic processGO:0009892860.015
positive regulation of multicellular organismal processGO:0051240520.015
skeletal system developmentGO:00015011810.015
growthGO:00400071740.015
regulation of angiogenesisGO:0045765260.015
response to abiotic stimulusGO:00096281220.015
positive regulation of gtp catabolic processGO:003312610.015
regulation of protein metabolic processGO:0051246560.015
cellular response to organic substanceGO:00713101050.015
embryonic skeletal system developmentGO:0048706970.015
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.015
proteasomal protein catabolic processGO:001049820.015
response to chemicalGO:00422213200.015
positive regulation of innate immune responseGO:004508980.015
mitotic dna damage checkpointGO:004477340.015
multi organism processGO:00517041340.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
regulation of response to stressGO:0080134360.015
mesenchymal cell developmentGO:0014031780.015
regulation of canonical wnt signaling pathwayGO:0060828340.015
cell substrate adherens junction assemblyGO:000704510.015
protein complex disassemblyGO:004324110.015
positive regulation of cell cycleGO:004578730.015
negative regulation of biosynthetic processGO:0009890550.015
cellular response to decreased oxygen levelsGO:003629410.015
single organism biosynthetic processGO:0044711710.014
negative regulation of signal transduction in absence of ligandGO:190109910.014
ventricular cardiac muscle tissue developmentGO:000322930.014
heart joggingGO:0003146400.014
extrinsic apoptotic signaling pathwayGO:009719130.014
peptidyl threonine modificationGO:001821010.014
eye morphogenesisGO:00485921440.014
behaviorGO:0007610740.014
embryonic skeletal system morphogenesisGO:0048704930.014
organic cyclic compound metabolic processGO:19013603010.014
regulation of nitrogen compound metabolic processGO:00511712510.014
glucose importGO:004632320.014
regulation of cell motilityGO:2000145460.014
immune system developmentGO:00025201910.014
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.014
striated muscle tissue developmentGO:00147061100.014
positive regulation of jnk cascadeGO:004633030.014
embryonic hemopoiesisGO:0035162530.014
regulation of autophagyGO:001050630.014
interaction with hostGO:005170140.014
negative regulation of dna replicationGO:000815620.014
urogenital system developmentGO:0001655970.014
retina morphogenesis in camera type eyeGO:0060042790.014
endocardial cushion morphogenesisGO:000320330.014
peptidyl serine modificationGO:001820920.014
regulation of intracellular signal transductionGO:1902531570.014
macromolecule modificationGO:00434121110.014
positive regulation of cellular amine metabolic processGO:003324000.014
apoptotic processGO:00069151160.014
negative regulation of epithelial cell proliferationGO:005068010.014
negative regulation of intracellular signal transductionGO:1902532220.014
cellular modified amino acid metabolic processGO:000657530.014
regulation of establishment of protein localization to plasma membraneGO:009000310.014
cellular response to starvationGO:000926710.014
intracellular transportGO:0046907320.014
olfactory bulb developmentGO:002177240.014
regulation of multicellular organismal processGO:00512392770.014
regulation of phosphorus metabolic processGO:0051174430.013
programmed cell deathGO:00125011190.013
regulation of rna metabolic processGO:00512522240.013
response to organic substanceGO:00100331530.013
taxisGO:00423301090.013
response to uvGO:000941130.013
stem cell divisionGO:001714510.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
cell part morphogenesisGO:00329902460.013
regulation of synaptic plasticityGO:004816710.013
regulation of stem cell proliferationGO:007209120.013
cellular amide metabolic processGO:004360340.013
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.013
cofactor metabolic processGO:0051186150.013
modification dependent protein catabolic processGO:001994130.013
striated muscle cell developmentGO:00550021080.013
immune system processGO:00023762410.013
water homeostasisGO:003010440.013
Zebrafish
regulation of phosphate metabolic processGO:0019220430.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
regulation of cell deathGO:00109411030.013
macromolecular complex assemblyGO:0065003350.013
neuron projection guidanceGO:0097485860.013
macromolecular complex subunit organizationGO:0043933740.013
hydrogen peroxide metabolic processGO:004274320.013
multi organism reproductive processGO:0044703360.013
glucose homeostasisGO:004259310.013
epithelial cell differentiationGO:00308551160.013
cardiac conductionGO:006133730.013
retinoic acid receptor signaling pathwayGO:0048384160.013
synaptic vesicle localizationGO:009747910.013
regulation of transmembrane transporter activityGO:002289820.013
regulation of bmp signaling pathwayGO:0030510390.013
negative regulation of rna metabolic processGO:0051253480.013
peptidyl threonine phosphorylationGO:001810710.013
regulation of cell cycleGO:0051726520.013
regulation of blood vessel sizeGO:005088020.012
epithelial tube morphogenesisGO:00605621480.012
neuronal action potentialGO:0019228180.012
negative regulation of gene expressionGO:0010629650.012
regulation of p38mapk cascadeGO:190074410.012
positive regulation of striated muscle tissue developmentGO:004584410.012
autophagyGO:000691440.012
diencephalon developmentGO:0021536580.012
regulation of biosynthetic processGO:00098892500.012
regulation of fatty acid metabolic processGO:001921710.012
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.012
myelinationGO:0042552180.012
regulation of cellular component organizationGO:0051128860.012
response to endogenous stimulusGO:0009719830.012
neuron projection developmentGO:00311751800.012
hormone biosynthetic processGO:004244630.012
single organism behaviorGO:0044708240.012
negative regulation of cellular metabolic processGO:0031324770.012
kidney developmentGO:0001822920.012
negative regulation of cellular catabolic processGO:003133030.012
positive regulation of small gtpase mediated signal transductionGO:005105710.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.012
specification of organ identityGO:001009220.012
cellular response to oxygen levelsGO:007145310.012
regulation of cell differentiationGO:00455951420.012
protein secretionGO:000930610.012
cellular component maintenanceGO:004395430.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
positive regulation of map kinase activityGO:004340630.012
negative regulation of cellular biosynthetic processGO:0031327550.012
renal system developmentGO:0072001940.012
regulation of rho gtpase activityGO:003231910.012
cellular response to endogenous stimulusGO:0071495680.012
detection of external stimulusGO:0009581240.012
regulation of meiotic cell cycleGO:005144510.012
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.012
meiotic cell cycle processGO:190304630.012
protein stabilizationGO:005082120.012
biosynthetic processGO:00090582940.011
negative regulation of dna metabolic processGO:005105340.011
cell junction maintenanceGO:003433120.011
ion transmembrane transportGO:0034220910.011
rna biosynthetic processGO:00327741810.011
gene expressionGO:00104672520.011
regulation of lipid transportGO:003236840.011
mesenchymal cell proliferationGO:001046310.011
cellular response to extracellular stimulusGO:003166820.011
positive regulation of mesenchymal cell proliferationGO:000205310.011
muscle cell migrationGO:001481240.011
negative regulation of macromolecule biosynthetic processGO:0010558480.011
protein dephosphorylationGO:000647030.011

tjp2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.068
disease of metabolismDOID:001466700.068
disease of anatomical entityDOID:700.052
musculoskeletal system diseaseDOID:1700.044
muscle tissue diseaseDOID:6600.037
muscular diseaseDOID:008000000.037
myopathyDOID:42300.028
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.023
cardiovascular system diseaseDOID:128700.023
cardiomyopathyDOID:005070000.018
intrinsic cardiomyopathyDOID:006003600.018
heart diseaseDOID:11400.018
connective tissue diseaseDOID:6500.017
organ system cancerDOID:005068600.016
nervous system diseaseDOID:86300.015
bone diseaseDOID:008000100.014