Danio rerio

7 known processes

hsd11b2

hydroxysteroid 11-beta dehydrogenase 2

(Aliases: wu:fi31d01)

hsd11b2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell surface receptor signaling pathwayGO:00071663250.220
negative regulation of biological processGO:00485193040.198
signal transductionGO:00071654550.152
muscle tissue developmentGO:00605371100.128
nitrogen compound metabolic processGO:00068073190.122
g protein coupled receptor signaling pathwayGO:0007186740.095
g1 s transition of mitotic cell cycleGO:000008210.087
regulation of response to stimulusGO:00485832690.086
otic vesicle formationGO:0030916270.081
cellular biosynthetic processGO:00442492860.081
Zebrafish
embryonic organ morphogenesisGO:00485622740.072
Zebrafish
positive regulation of biological processGO:00485182530.072
regulation of nucleobase containing compound metabolic processGO:00192192500.068
regulation of programmed cell deathGO:00430671010.066
mitochondrion organizationGO:000700540.062
multicellular organism growthGO:003526440.060
cellular response to extracellular stimulusGO:003166820.060
organic cyclic compound metabolic processGO:19013603010.059
Rat
cellular response to external stimulusGO:007149620.059
negative regulation of response to stimulusGO:00485851040.058
regulation of macromolecule metabolic processGO:00602553170.055
positive regulation of cellular component biogenesisGO:004408930.054
skeletal muscle organ developmentGO:0060538780.053
response to abiotic stimulusGO:00096281220.052
Rat
cellular nitrogen compound metabolic processGO:00346412900.052
cell cycle g1 s phase transitionGO:004484310.052
positive regulation of cellular catabolic processGO:003133130.052
regulation of signalingGO:00230512350.052
small molecule metabolic processGO:0044281770.051
Zebrafish
nucleobase containing compound metabolic processGO:00061392740.051
developmental growthGO:00485891660.050
blood vessel morphogenesisGO:00485142160.049
gtp catabolic processGO:000618420.047
chordate embryonic developmentGO:00430092710.047
head developmentGO:00603223030.047
negative regulation of multicellular organismal processGO:0051241690.046
regulation of cell communicationGO:00106462320.045
cellular response to nutrient levelsGO:003166920.045
membrane fusionGO:006102520.044
single organism biosynthetic processGO:0044711710.043
Zebrafish
stem cell maintenanceGO:001982740.042
otic vesicle developmentGO:0071599420.041
morphogenesis of an epitheliumGO:00020093330.041
Zebrafish
regulation of multicellular organism growthGO:004001440.040
vasculature developmentGO:00019442780.040
specification of symmetryGO:00097992040.040
Zebrafish
organic cyclic compound biosynthetic processGO:19013622230.040
negative regulation of signalingGO:0023057960.039
larval developmentGO:000216420.039
agingGO:000756820.039
heterocycle biosynthetic processGO:00181302150.039
regulation of cell deathGO:00109411030.038
programmed cell deathGO:00125011190.038
establishment of protein localization to plasma membraneGO:009000210.038
endocrine system developmentGO:0035270650.038
Zebrafish
central nervous system developmentGO:00074173870.038
lateral inhibitionGO:004633110.037
aromatic compound biosynthetic processGO:00194382170.037
muscle structure developmentGO:00610611960.036
blood vessel developmentGO:00015682460.036
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.036
establishment of localizationGO:00512342440.036
guanosine containing compound catabolic processGO:190106920.036
multicellular organismal metabolic processGO:004423620.036
gtp metabolic processGO:004603940.036
cellular aromatic compound metabolic processGO:00067252950.036
transcription dna templatedGO:00063511810.036
response to carbohydrateGO:000974330.036
regulation of bindingGO:005109830.035
adult behaviorGO:003053420.035
negative regulation of developmental processGO:0051093650.034
glucose homeostasisGO:004259310.034
regulation of cellular metabolic processGO:00313233200.034
regulation of signal transductionGO:00099662250.033
response to chemicalGO:00422213200.033
Rat
nucleobase containing compound biosynthetic processGO:00346542050.033
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.033
positive regulation of response to stimulusGO:0048584800.032
heterocycle metabolic processGO:00464832900.032
energy reserve metabolic processGO:000611220.032
regulation of metabolic processGO:00192223590.032
positive regulation of catabolic processGO:000989640.032
organonitrogen compound metabolic processGO:1901564740.031
regulation of reproductive processGO:200024140.031
regulation of protein complex assemblyGO:004325430.031
germ line stem cell maintenanceGO:003071820.030
response to light stimulusGO:0009416460.030
digestive system developmentGO:00551232890.030
Zebrafish
mesenchyme developmentGO:00604851270.030
Zebrafish
gland developmentGO:00487321430.029
organic acid metabolic processGO:0006082310.029
positive regulation of transportGO:005105020.029
regulation of developmental processGO:00507932470.028
cellular nitrogen compound biosynthetic processGO:00442712180.028
negative regulation of cellular processGO:00485232830.028
growthGO:00400071740.028
regulation of neuron migrationGO:200122220.028
positive regulation of secretion by cellGO:190353210.028
guanosine containing compound metabolic processGO:190106840.028
hemopoiesisGO:00300971830.028
regulation of nitrogen compound metabolic processGO:00511712510.027
hormone transportGO:000991420.027
cell growthGO:0016049570.027
regulation of rna metabolic processGO:00512522240.027
cellular response to chemical stimulusGO:00708871570.027
regulation of nucleotide catabolic processGO:003081120.027
cellular response to starvationGO:000926710.027
heart developmentGO:00075073130.027
Zebrafish
organic substance biosynthetic processGO:19015762890.026
Zebrafish
cell part morphogenesisGO:00329902460.026
cell fate commitmentGO:0045165990.026
cell morphogenesisGO:00009022890.026
rna biosynthetic processGO:00327741810.026
regulation of cell cycleGO:0051726520.026
regulation of cell activationGO:005086510.026
cellular component morphogenesisGO:00329893360.026
regulation of blood pressureGO:000821710.025
Rat
camera type eye developmentGO:00430102220.025
Zebrafish
cellular macromolecule metabolic processGO:00442603910.025
immune system processGO:00023762410.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.025
regulation of rna biosynthetic processGO:20011412130.025
negative regulation of cellular biosynthetic processGO:0031327550.025
regulation of response to nutrient levelsGO:003210710.025
regionalizationGO:00030022740.025
regulation of apoptotic processGO:0042981980.025
regulation of muscle contractionGO:000693730.024
regulation of cell shapeGO:000836010.024
positive regulation of cell cycleGO:004578730.024
regulation of multicellular organismal processGO:00512392770.024
response to biotic stimulusGO:0009607970.024
carbohydrate homeostasisGO:003350010.024
muscle organ developmentGO:00075171010.024
positive regulation of gtp catabolic processGO:003312610.024
digestive tract developmentGO:00485652650.024
Zebrafish
cellular macromolecule biosynthetic processGO:00346452240.024
regulation of gtp catabolic processGO:003312420.024
nucleic acid templated transcriptionGO:00976591810.024
regulation of anatomical structure morphogenesisGO:00226031300.023
cell proliferationGO:0008283800.023
single organism metabolic processGO:00447102170.023
Zebrafish Rat
regulation of multicellular organismal metabolic processGO:004424620.023
neuron differentiationGO:00301823530.023
Zebrafish
cardiac atrium developmentGO:000323040.023
regulation of macromolecule biosynthetic processGO:00105562250.023
oxoacid metabolic processGO:0043436310.023
regulation of cellular amino acid metabolic processGO:000652100.023
sensory perception of painGO:001923310.023
hormone secretionGO:004687920.023
regulation of biological qualityGO:00650082630.023
Zebrafish Rat
negative regulation of signal transductionGO:0009968940.023
positive regulation of purine nucleotide catabolic processGO:003312310.022
protein secretionGO:000930610.022
brain developmentGO:00074202930.022
single organism membrane fusionGO:004480120.022
collagen metabolic processGO:003296320.021
cellular amine metabolic processGO:004410620.021
response to glucoseGO:000974930.021
enzyme linked receptor protein signaling pathwayGO:00071671060.021
regulation of cellular biosynthetic processGO:00313262450.021
regulation of purine nucleotide catabolic processGO:003312120.021
determination of bilateral symmetryGO:00098552040.021
Zebrafish
regulation of nucleic acid templated transcriptionGO:19035062130.021
regulation of collagen metabolic processGO:001071220.021
regulation of primary metabolic processGO:00800903110.020
biosynthetic processGO:00090582940.020
Zebrafish
positive regulation of blood circulationGO:190352420.020
carbohydrate biosynthetic processGO:001605110.020
striated muscle tissue developmentGO:00147061100.020
peptide transportGO:001583310.020
regulation of response to extracellular stimulusGO:003210410.020
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.020
positive regulation of secretionGO:005104710.020
hindbrain developmentGO:0030902910.020
immune system developmentGO:00025201910.020
regulation of cell developmentGO:00602841000.020
positive regulation of muscle organ developmentGO:004863610.020
regulation of protein transportGO:005122330.020
regulation of cellular carbohydrate metabolic processGO:001067540.020
regulation of reactive oxygen species metabolic processGO:200037720.020
negative regulation of cell communicationGO:0010648960.020
negative regulation of biosynthetic processGO:0009890550.020
carboxylic acid metabolic processGO:0019752220.020
regulation of mitochondrion organizationGO:001082110.019
gene expressionGO:00104672520.019
establishment of protein localization to organelleGO:007259440.019
transportGO:00068102200.019
regulation of establishment of protein localizationGO:007020140.019
cellular ketone metabolic processGO:0042180110.019
regulation of heart growthGO:006042020.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
cell matrix adhesionGO:000716040.019
regulation of nucleoside metabolic processGO:000911820.019
cell projection morphogenesisGO:00488582440.019
regulation of organ growthGO:004662030.019
maintenance of locationGO:005123540.019
deathGO:00162651210.019
cellular amino acid metabolic processGO:000652070.019
regulation of cellular ketone metabolic processGO:001056570.018
regulation of cellular component organizationGO:0051128860.018
regulation of epithelial cell proliferationGO:005067830.018
multicellular organismal response to stressGO:003355520.018
regulation of transcription dna templatedGO:00063552130.018
neuron projection morphogenesisGO:00488121610.018
regulation of gtpase activityGO:004308720.018
hematopoietic or lymphoid organ developmentGO:00485341910.018
synaptic growth at neuromuscular junctionGO:005112420.018
regulation of metal ion transportGO:001095940.018
regulation of phosphorus metabolic processGO:0051174430.018
positive regulation of nucleoside metabolic processGO:004597910.018
regulation of ion transmembrane transporter activityGO:003241220.018
negative regulation of epithelial cell proliferationGO:005068010.017
protein localization to plasma membraneGO:007265910.017
pancreas developmentGO:0031016840.017
Zebrafish
pericardium developmentGO:006003910.017
angiogenesisGO:00015251580.017
cell morphogenesis involved in differentiationGO:00009041950.017
cell migrationGO:00164772370.017
hormone biosynthetic processGO:004244630.017
apoptotic processGO:00069151160.017
regulation of biosynthetic processGO:00098892500.017
response to vitaminGO:003327330.017
transcription from rna polymerase ii promoterGO:0006366800.017
ventricular cardiac muscle tissue developmentGO:000322930.017
cell cycle arrestGO:000705010.017
stem cell differentiationGO:00488631170.017
Zebrafish
cognitionGO:005089010.017
response to hexoseGO:000974630.017
regulation of multicellular organismal developmentGO:20000262230.017
regulation of cytokine productionGO:000181730.016
axon ensheathment in central nervous systemGO:003229120.016
cellular carbohydrate metabolic processGO:004426240.016
axon developmentGO:00615641660.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
neurotransmitter secretionGO:000726920.016
positive regulation of nucleotide catabolic processGO:003081310.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.016
cell deathGO:00082191210.016
cell fate specificationGO:0001708680.016
positive regulation of gtpase activityGO:004354710.016
cardiac atrium morphogenesisGO:000320920.016
response to external stimulusGO:00096052640.016
Rat
regulation of endothelial cell proliferationGO:000193610.016
regulation of glial cell differentiationGO:004568540.015
embryo development ending in birth or egg hatchingGO:00097922710.015
positive regulation of programmed cell deathGO:0043068290.015
purine containing compound biosynthetic processGO:0072522200.015
cellular response to radiationGO:007147840.015
nuclear transportGO:005116940.015
positive regulation of striated muscle tissue developmentGO:004584410.015
response to nutrientGO:000758430.015
response to radiationGO:0009314510.015
embryonic organ developmentGO:00485683810.015
Zebrafish
alpha amino acid metabolic processGO:190160530.015
membrane hyperpolarizationGO:006008110.015
negative regulation of small gtpase mediated signal transductionGO:005105810.015
response to foodGO:003209410.015
Rat
regulation of cell projection assemblyGO:006049140.015
positive regulation of cell adhesionGO:004578510.015
response to uvGO:000941130.015
regulation of gene expressionGO:00104682650.015
negative regulation of metabolic processGO:0009892860.014
cellular response to oxygen levelsGO:007145310.014
pigmentationGO:0043473850.014
amine metabolic processGO:000930820.014
cell substrate adhesionGO:003158940.014
erythrocyte differentiationGO:0030218540.014
regulation of protein bindingGO:004339330.014
negative regulation of cellular metabolic processGO:0031324770.014
regulation of bmp signaling pathwayGO:0030510390.014
response to topologically incorrect proteinGO:003596620.014
protein targeting to nucleusGO:004474430.014
photoreceptor cell fate commitmentGO:004655210.014
endocrine processGO:005088620.014
Rat
regulation of cell migrationGO:0030334400.014
sensory organ developmentGO:00074233930.014
Zebrafish
regulation of carbohydrate biosynthetic processGO:004325510.014
circulatory system processGO:0003013870.014
Zebrafish Rat
ossificationGO:0001503230.014
localization of cellGO:00516742440.014
response to ketoneGO:190165410.014
regulation of cell differentiationGO:00455951420.014
positive regulation of cellular amine metabolic processGO:003324000.014
neurological system processGO:0050877620.014
tube morphogenesisGO:00352393490.014
Zebrafish
water homeostasisGO:003010440.013
single organism transportGO:00447652060.013
exocrine system developmentGO:0035272280.013
Zebrafish
cell morphogenesis involved in neuron differentiationGO:00486671630.013
nucleocytoplasmic transportGO:000691340.013
protein metabolic processGO:00195381830.013
response to stressGO:00069502630.013
response to organic substanceGO:00100331530.013
Rat
regulation of skeletal muscle tissue developmentGO:004864140.013
mesoderm developmentGO:0007498880.013
cellular component movementGO:00069283350.013
homeostatic processGO:00425921420.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
lymphocyte proliferationGO:004665110.013
eye developmentGO:00016542770.013
Zebrafish
regulation of cellular amine metabolic processGO:003323800.013
response to drugGO:004249330.013
Rat
cellular response to stressGO:0033554620.013
glucocorticoid metabolic processGO:000821120.013
Rat
regulation of carbohydrate metabolic processGO:000610940.013
apoptotic process involved in developmentGO:190274220.013
positive regulation of myeloid cell differentiationGO:004563920.013
negative regulation of protein phosphorylationGO:000193340.013
small molecule biosynthetic processGO:0044283160.013
Zebrafish
gastrulationGO:00073692080.013
meiotic cell cycle processGO:190304630.013
macromolecule biosynthetic processGO:00090592270.013
columnar cuboidal epithelial cell differentiationGO:0002065380.013
mitotic dna damage checkpointGO:004477340.013
regulation of hormone levelsGO:0010817210.013
Zebrafish
intracellular signal transductionGO:0035556850.013
cytosolic calcium ion transportGO:006040130.013
otic vesicle morphogenesisGO:0071600340.013
cell adhesion mediated by integrinGO:003362710.013
regulation of synaptic plasticityGO:004816710.013
energy homeostasisGO:009700930.013
single organism nuclear importGO:190259330.012
skeletal muscle tissue developmentGO:0007519670.012
regulation of intracellular protein transportGO:003315730.012
regulation of cytoplasmic transportGO:190364940.012
response to hormoneGO:0009725480.012
Rat
positive regulation of cellular amino acid metabolic processGO:004576400.012
sequestering of metal ionGO:005123830.012
regulation of hormone secretionGO:004688320.012
regulation of autophagyGO:001050630.012
heart morphogenesisGO:00030071560.012
Zebrafish
hepaticobiliary system developmentGO:0061008980.012
regulation of calcium ion transportGO:005192420.012
rna metabolic processGO:00160702190.012
positive regulation of cellular metabolic processGO:0031325940.012
muscle hypertrophyGO:001489620.012
skeletal system developmentGO:00015011810.012
Zebrafish
negative regulation of cell deathGO:0060548600.012
regulation of neuron differentiationGO:0045664560.012
neural tube developmentGO:0021915620.012
axonogenesisGO:00074091520.012
cell projection organizationGO:00300302840.012
neuron developmentGO:00486662620.012
response to monosaccharideGO:003428430.012
positive regulation of muscle tissue developmentGO:190186310.012
lymph vessel developmentGO:0001945270.012
positive regulation of apoptotic processGO:0043065290.012
negative regulation of programmed cell deathGO:0043069580.012
positive regulation of muscle cell differentiationGO:005114910.012
negative regulation of bmp signaling pathwayGO:0030514130.012
positive regulation of epithelial cell migrationGO:001063420.012
cell agingGO:000756920.012
ear developmentGO:00435831270.012
development of primary female sexual characteristicsGO:004654540.012
protein importGO:001703830.011
positive regulation of cellular carbohydrate metabolic processGO:001067610.011
intracellular mrna localizationGO:000829810.011
cyclic purine nucleotide metabolic processGO:0052652180.011
peptide metabolic processGO:000651810.011
positive regulation of carbohydrate metabolic processGO:004591310.011
regulation of cardiac muscle tissue developmentGO:005502410.011
reactive oxygen species metabolic processGO:007259360.011
nuclear importGO:005117030.011
multi organism processGO:00517041340.011
Mouse Rat
spermatid differentiationGO:004851520.011
positive regulation of cellular processGO:00485222010.011
cell motilityGO:00488702440.011
regulation of transporter activityGO:003240920.011
negative regulation of secretion by cellGO:190353120.011
peripheral nervous system developmentGO:0007422550.011
macroautophagyGO:001623610.011
negative regulation of dna metabolic processGO:005105340.011
negative regulation of macromolecule metabolic processGO:0010605760.011
nucleic acid metabolic processGO:00903042440.011
eye morphogenesisGO:00485921440.011
Zebrafish
sensory organ morphogenesisGO:00905962000.011
Zebrafish
female sex differentiationGO:004666040.011
ribose phosphate biosynthetic processGO:0046390200.011
regulation of establishment of protein localization to plasma membraneGO:009000310.011
hatching gland developmentGO:004878530.011
regulation of transmembrane transporter activityGO:002289820.011
negative regulation of ras protein signal transductionGO:004658010.011
regulation of blood vessel sizeGO:005088020.011
protein polymerizationGO:005125840.011
multicellular organismal macromolecule metabolic processGO:004425920.011
mesenchymal cell differentiationGO:0048762870.011
Zebrafish
regulation of dna replicationGO:000627530.011
positive regulation of heart contractionGO:004582320.011
response to corticosteroidGO:003196010.010
Rat
ras protein signal transductionGO:000726570.010
negative regulation of kinase activityGO:003367340.010
positive regulation of cell activationGO:005086710.010
cyclic nucleotide biosynthetic processGO:0009190180.010
positive regulation of metabolic processGO:00098931080.010
negative regulation of feeding behaviorGO:200025220.010
regulation of dendrite developmentGO:005077330.010
sleepGO:003043110.010
single organism localizationGO:19025782250.010
stem cell proliferationGO:007208940.010
central nervous system myelinationGO:002201020.010
skeletal system morphogenesisGO:00487051020.010
epithelial tube morphogenesisGO:00605621480.010
Zebrafish
endocrine pancreas developmentGO:0031018270.010
Zebrafish
autophagyGO:000691440.010
phosphate containing compound metabolic processGO:00067961080.010
sprouting angiogenesisGO:0002040530.010

hsd11b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.013
organ system cancerDOID:005068600.013
disease of cellular proliferationDOID:1456600.013
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.012
disease of anatomical entityDOID:700.012
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011
musculoskeletal system diseaseDOID:1700.011