Danio rerio

8 known processes

crb1

crumbs homolog 1 (Drosophila)

(Aliases: si:dkey-114d20.6,si:dkey-114d20.7)

crb1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
apical protein localizationGO:004517660.488
Zebrafish
regulation of signalingGO:00230512350.353
Zebrafish
brain developmentGO:00074202930.268
Zebrafish
cellular response to radiationGO:007147840.259
regulation of signal transductionGO:00099662250.215
Zebrafish
generation of neuronsGO:00486993850.206
Zebrafish
cellular component movementGO:00069283350.205
eye photoreceptor cell developmentGO:0042462300.201
Zebrafish
ameboidal type cell migrationGO:00016671430.186
signal transductionGO:00071654550.181
Zebrafish
cellular macromolecule metabolic processGO:00442603910.173
cilium organizationGO:0044782710.172
Zebrafish
peripheral nervous system developmentGO:0007422550.162
ion transmembrane transportGO:0034220910.162
neuron developmentGO:00486662620.156
Zebrafish
regulation of metabolic processGO:00192223590.142
neuron differentiationGO:00301823530.142
Zebrafish
single organism organelle organizationGO:19025891990.138
Zebrafish
regulation of cellular metabolic processGO:00313233200.127
negative regulation of biological processGO:00485193040.125
Zebrafish
retina morphogenesis in camera type eyeGO:0060042790.121
Zebrafish
establishment or maintenance of apical basal cell polarityGO:0035088120.116
negative regulation of cellular processGO:00485232830.105
Zebrafish
synaptic transmissionGO:0007268350.104
cellular response to light stimulusGO:007148240.101
medulla oblongata developmentGO:002155040.099
regulation of cell differentiationGO:00455951420.099
retina development in camera type eyeGO:00600411460.097
Zebrafish
regulation of cellular amine metabolic processGO:003323800.094
regulation of notch signaling pathwayGO:0008593160.093
Zebrafish
nitrogen compound metabolic processGO:00068073190.091
carboxylic acid metabolic processGO:0019752220.090
axon ensheathment in central nervous systemGO:003229120.090
head developmentGO:00603223030.089
Zebrafish
regulation of canonical wnt signaling pathwayGO:0060828340.089
Zebrafish
eye morphogenesisGO:00485921440.087
Zebrafish
homeostasis of number of cellsGO:0048872620.086
developmental programmed cell deathGO:001062340.086
neuron neuron synaptic transmissionGO:000727010.085
dorsal motor nucleus of vagus nerve developmentGO:002174440.084
neurological system processGO:0050877620.084
inner ear developmentGO:00488391260.082
maintenance of epithelial cell apical basal polarityGO:004519950.081
asymmetric protein localizationGO:000810560.079
Zebrafish
glial cell developmentGO:0021782200.078
renal system developmentGO:0072001940.078
Zebrafish
positive regulation of notch signaling pathwayGO:004574730.077
regulation of cellular amino acid metabolic processGO:000652100.073
cilium assemblyGO:0042384580.073
Zebrafish
regulation of primary metabolic processGO:00800903110.072
positive regulation of cgmp biosynthetic processGO:003082860.070
amine metabolic processGO:000930820.068
agingGO:000756820.068
regulation of cell communicationGO:00106462320.068
Zebrafish
chordate embryonic developmentGO:00430092710.067
cell migrationGO:00164772370.067
pronephros developmentGO:0048793690.066
Zebrafish
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.066
Zebrafish
amino acid transportGO:000686520.066
positive regulation of cellular amino acid metabolic processGO:004576400.062
cellular nitrogen compound metabolic processGO:00346412900.062
phototransductionGO:000760220.061
central nervous system developmentGO:00074173870.061
Zebrafish
system processGO:00030081850.061
Zebrafish
cell projection organizationGO:00300302840.060
Zebrafish
stem cell developmentGO:0048864820.059
sensory organ morphogenesisGO:00905962000.056
Zebrafish
camera type eye morphogenesisGO:00485931080.056
Zebrafish
nucleic acid metabolic processGO:00903042440.056
establishment of localizationGO:00512342440.054
regulation of macromolecule metabolic processGO:00602553170.054
canonical wnt signaling pathwayGO:0060070480.053
Zebrafish
cell motilityGO:00488702440.053
multicellular organism growthGO:003526440.051
cilium morphogenesisGO:0060271850.051
Zebrafish
regulation of biological qualityGO:00650082630.050
positive regulation of leukocyte differentiationGO:190210710.050
regulation of peptidyl tyrosine phosphorylationGO:005073010.050
regulation of multicellular organism growthGO:004001440.050
mesenchyme developmentGO:00604851270.049
organelle organizationGO:00069962270.048
Zebrafish
detection of visible lightGO:0009584120.047
eye developmentGO:00016542770.047
Zebrafish
hindbrain developmentGO:0030902910.047
morphogenesis of an epitheliumGO:00020093330.047
negative regulation of signalingGO:0023057960.047
Zebrafish
positive regulation of guanylate cyclase activityGO:003128460.047
embryo development ending in birth or egg hatchingGO:00097922710.046
locomotionGO:00400113130.046
regulation of nitrogen compound metabolic processGO:00511712510.046
cell projection morphogenesisGO:00488582440.045
Zebrafish
cellular component morphogenesisGO:00329893360.044
Zebrafish
regulation of gene expressionGO:00104682650.043
positive regulation of epithelial cell differentiationGO:003085820.043
visual perceptionGO:0007601170.043
cellular amino acid metabolic processGO:000652070.042
hair cell differentiationGO:0035315320.042
axon ensheathmentGO:0008366180.042
cell morphogenesisGO:00009022890.042
Zebrafish
skin developmentGO:0043588540.042
heart morphogenesisGO:00030071560.041
neurotransmitter secretionGO:000726920.040
cgmp biosynthetic processGO:000618270.040
adherens junction organizationGO:003433240.040
cellular ketone metabolic processGO:0042180110.039
lateral line ganglion developmentGO:004889020.039
regulation of synaptic plasticityGO:004816710.039
regulation of nucleobase containing compound metabolic processGO:00192192500.039
peptide transportGO:001583310.039
cellular amine metabolic processGO:004410620.038
mesenchymal cell developmentGO:0014031780.037
nephron developmentGO:0072006310.037
Zebrafish
biosynthetic processGO:00090582940.036
response to hexoseGO:000974630.036
epithelial tube formationGO:0072175190.036
glial cell proliferationGO:001400940.036
striated muscle cell differentiationGO:00511461290.036
digestive tract morphogenesisGO:00485462310.035
negative regulation of response to stimulusGO:00485851040.035
Zebrafish
cellular protein modification processGO:00064641000.035
sensory perception of light stimulusGO:0050953190.035
growthGO:00400071740.035
oxoacid metabolic processGO:0043436310.034
multicellular organismal signalingGO:0035637220.034
positive regulation of catabolic processGO:000989640.034
neural nucleus developmentGO:0048857150.034
regulation of neural precursor cell proliferationGO:200017730.034
regulation of circadian rhythmGO:004275240.033
detection of stimulusGO:0051606290.033
regulation of stem cell differentiationGO:200073640.033
leukocyte proliferationGO:007066110.033
positive regulation of map kinase activityGO:004340630.032
muscle cell developmentGO:00550011150.032
polarized epithelial cell differentiationGO:003085940.032
positive regulation of biological processGO:00485182530.031
organonitrogen compound metabolic processGO:1901564740.031
positive regulation of cellular amine metabolic processGO:003324000.031
regulation of cellular ketone metabolic processGO:001056570.031
regulation of neurotransmitter transportGO:005158810.031
regulation of wnt signaling pathwayGO:0030111530.031
Zebrafish
cellular component biogenesisGO:00440851780.031
Zebrafish
sympathetic nervous system developmentGO:004848530.031
cellular component assembly involved in morphogenesisGO:00109271070.031
Zebrafish
photoreceptor cell differentiationGO:0046530550.031
Zebrafish
positive regulation of cellular processGO:00485222010.030
vasculature developmentGO:00019442780.030
regulation of cellular macromolecule biosynthetic processGO:20001122220.030
cellular aromatic compound metabolic processGO:00067252950.030
regulation of multicellular organismal processGO:00512392770.030
glomerulus developmentGO:0032835270.030
Zebrafish
mesenchymal cell differentiationGO:0048762870.030
regulation of neurotransmitter secretionGO:004692810.030
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.029
Zebrafish
embryonic heart tube developmentGO:00350501330.029
cell cell adhesionGO:009860960.029
Zebrafish
camera type eye developmentGO:00430102220.029
Zebrafish
epidermal cell fate specificationGO:000995740.029
smoothened signaling pathwayGO:0007224300.028
localization of cellGO:00516742440.028
regulation of developmental processGO:00507932470.028
transmembrane transportGO:00550851200.028
positive regulation of cell communicationGO:0010647560.028
response to amino acidGO:004320020.028
photoreceptor cell developmentGO:0042461400.027
Zebrafish
peptidyl serine phosphorylationGO:001810510.027
positive regulation of myeloid cell differentiationGO:004563920.026
nucleobase containing compound metabolic processGO:00061392740.026
stem cell proliferationGO:007208940.026
response to metal ionGO:0010038340.026
action potentialGO:0001508190.026
single organism transportGO:00447652060.026
embryonic skeletal system developmentGO:0048706970.026
maintenance of locationGO:005123540.025
negative regulation of kinase activityGO:003367340.025
macromolecule modificationGO:00434121110.025
digestive system developmentGO:00551232890.024
muscle structure developmentGO:00610611960.024
heterocycle metabolic processGO:00464832900.024
negative regulation of cell communicationGO:0010648960.024
Zebrafish
positive regulation of cell cycleGO:004578730.024
negative regulation of gliogenesisGO:001401410.024
stem cell maintenanceGO:001982740.024
myelinationGO:0042552180.023
cell cell adhesion via plasma membrane adhesion moleculesGO:009874260.023
Zebrafish
determination of bilateral symmetryGO:00098552040.023
regulation of cyclic nucleotide metabolic processGO:0030799150.023
regulation of cgmp biosynthetic processGO:003082660.023
embryonic cranial skeleton morphogenesisGO:0048701900.023
ear developmentGO:00435831270.023
epidermis developmentGO:0008544480.023
gliogenesisGO:0042063450.022
neuronal action potentialGO:0019228180.022
cellular macromolecule biosynthetic processGO:00346452240.022
positive regulation of glucose transportGO:001082810.022
water homeostasisGO:003010440.022
organic substance biosynthetic processGO:19015762890.022
response to glucoseGO:000974930.022
gene expressionGO:00104672520.022
transportGO:00068102200.022
muscle organ developmentGO:00075171010.022
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.022
regulation of meiotic cell cycleGO:005144510.021
apoptotic processGO:00069151160.021
negative regulation of protein serine threonine kinase activityGO:007190120.021
response to monosaccharideGO:003428430.021
negative regulation of canonical wnt signaling pathwayGO:0090090210.021
Zebrafish
regulation of bindingGO:005109830.021
cell substrate adherens junction assemblyGO:000704510.021
negative regulation of protein kinase activityGO:000646940.021
sensory organ developmentGO:00074233930.021
Zebrafish
blood vessel developmentGO:00015682460.021
programmed cell deathGO:00125011190.021
cell surface receptor signaling pathwayGO:00071663250.021
Zebrafish
muscle cell differentiationGO:00426921390.021
regulation of reproductive processGO:200024140.020
regulation of multicellular organismal developmentGO:20000262230.020
receptor recyclingGO:000188140.020
establishment or maintenance of cell polarityGO:0007163290.020
photoreceptor cell fate commitmentGO:004655210.020
mitotic cell cycleGO:0000278640.020
positive regulation of gene expressionGO:0010628710.020
regulation of hormone secretionGO:004688320.020
cell matrix adhesionGO:000716040.020
developmental growth involved in morphogenesisGO:0060560860.020
regulation of membrane potentialGO:0042391230.020
guanosine containing compound metabolic processGO:190106840.020
neuroblast proliferationGO:000740520.020
glomerular filtrationGO:000309460.020
Zebrafish
positive regulation of biosynthetic processGO:0009891680.020
extrinsic apoptotic signaling pathwayGO:009719130.020
heterocycle biosynthetic processGO:00181302150.020
hematopoietic or lymphoid organ developmentGO:00485341910.019
cell substrate adhesionGO:003158940.019
toxin transportGO:190199820.019
angiogenesisGO:00015251580.019
organic cyclic compound metabolic processGO:19013603010.019
hemopoiesisGO:00300971830.019
positive regulation of developmental processGO:0051094500.019
hormone transportGO:000991420.019
positive regulation of transportGO:005105020.019
establishment of localization in cellGO:0051649770.019
exocytosisGO:000688710.019
myeloid cell differentiationGO:0030099860.019
epithelial cell differentiationGO:00308551160.019
production of molecular mediator of immune responseGO:000244020.019
single organism localizationGO:19025782250.019
glial cell differentiationGO:0010001420.019
transmission of nerve impulseGO:0019226190.019
proteasomal protein catabolic processGO:001049820.018
negative regulation of map kinase activityGO:004340720.018
regulation of protein bindingGO:004339330.018
phototransduction visible lightGO:000760320.018
notch signaling pathwayGO:0007219350.018
Zebrafish
autophagyGO:000691440.018
wnt signaling pathwayGO:0016055800.018
Zebrafish
positive regulation of inflammatory responseGO:005072910.018
synaptic transmission cholinergicGO:000727140.018
response to carbohydrateGO:000974330.017
organic acid metabolic processGO:0006082310.017
modification dependent macromolecule catabolic processGO:004363230.017
embryonic viscerocranium morphogenesisGO:0048703520.017
digestive tract developmentGO:00485652650.017
kidney developmentGO:0001822920.017
Zebrafish
circadian sleep wake cycle sleepGO:005080210.017
cognitionGO:005089010.017
urogenital system developmentGO:0001655970.017
Zebrafish
neural tube formationGO:0001841160.017
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.017
gastrulationGO:00073692080.017
positive regulation of metabolic processGO:00098931080.017
tube morphogenesisGO:00352393490.017
regulation of dendrite developmentGO:005077330.017
stem cell divisionGO:001714510.017
positive regulation of nitrogen compound metabolic processGO:0051173690.017
regulation of mrna processingGO:005068430.017
cellular nitrogen compound biosynthetic processGO:00442712180.017
regulation of inflammatory responseGO:005072720.017
adherens junction assemblyGO:003433310.017
myeloid cell homeostasisGO:0002262560.016
negative regulation of protein phosphorylationGO:000193340.016
glucose importGO:004632320.016
negative regulation of signal transductionGO:0009968940.016
Zebrafish
negative regulation of notch signaling pathwayGO:004574660.016
Zebrafish
immune system processGO:00023762410.016
peptidyl threonine phosphorylationGO:001810710.016
regulation of neurogenesisGO:0050767870.016
regulation of biosynthetic processGO:00098892500.016
embryonic organ developmentGO:00485683810.016
regulation of protein complex assemblyGO:004325430.016
carbohydrate homeostasisGO:003350010.016
negative regulation of histone modificationGO:003105710.016
response to drugGO:004249330.016
chemotaxisGO:00069351040.015
striated muscle cell developmentGO:00550021080.015
positive regulation of macromolecule metabolic processGO:0010604930.015
positive regulation of cell adhesionGO:004578510.015
deathGO:00162651210.015
meiotic cell cycle processGO:190304630.015
sodium ion transmembrane transportGO:0035725210.015
inorganic cation transmembrane transportGO:0098662500.015
regulation of glucose transportGO:001082710.015
regulation of cellular biosynthetic processGO:00313262450.015
gtp metabolic processGO:004603940.015
lipid catabolic processGO:001604240.015
phagocytosisGO:000690930.015
small molecule catabolic processGO:004428230.015
positive regulation of cellular catabolic processGO:003133130.015
regulation of programmed cell deathGO:00430671010.015
forebrain developmentGO:0030900960.015
positive regulation of signal transductionGO:0009967560.015
chemosensory behaviorGO:000763510.015
rna metabolic processGO:00160702190.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
actin filament based movementGO:003004810.015
astrocyte differentiationGO:004870810.014
single organismal cell cell adhesionGO:0016337290.014
Zebrafish
energy reserve metabolic processGO:000611220.014
developmental growthGO:00485891660.014
microtubule based movementGO:0007018330.014
maintenance of cell polarityGO:003001150.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
multicellular organismal response to stressGO:003355520.014
negative regulation of epithelial cell proliferationGO:005068010.014
biological adhesionGO:0022610400.014
Zebrafish
cell fate specificationGO:0001708680.014
cellular localizationGO:0051641970.014
establishment of synaptic vesicle localizationGO:009748010.014
single organism nuclear importGO:190259330.014
sequestering of metal ionGO:005123830.014
regulation of anatomical structure morphogenesisGO:00226031300.014
cell adhesionGO:0007155400.014
Zebrafish
regulation of phospholipase activityGO:001051720.014
response to chemicalGO:00422213200.014
positive regulation of cellular metabolic processGO:0031325940.014
gtp catabolic processGO:000618420.014
fatty acid transportGO:001590810.014
positive regulation of signalingGO:0023056560.014
negative regulation of secretion by cellGO:190353120.014
calcium ion dependent exocytosisGO:001715610.013
circadian sleep wake cycle processGO:002241020.013
cellular component assemblyGO:00226071700.013
Zebrafish
nucleocytoplasmic transportGO:000691340.013
protein acylationGO:004354330.013
renal filtrationGO:0097205100.013
Zebrafish
protein heterooligomerizationGO:005129110.013
negative regulation of dna metabolic processGO:005105340.013
central nervous system myelinationGO:002201020.013
positive regulation of response to stimulusGO:0048584800.013
stem cell differentiationGO:00488631170.013
cell deathGO:00082191210.013
auditory receptor cell differentiationGO:0042491150.013
guanosine containing compound catabolic processGO:190106920.013
cellular biosynthetic processGO:00442492860.013
small molecule metabolic processGO:0044281770.013
protein metabolic processGO:00195381830.013
ubiquitin dependent protein catabolic processGO:000651130.013
small gtpase mediated signal transductionGO:000726480.013
epithelial to mesenchymal transitionGO:0001837210.013
regulation of response to stimulusGO:00485832690.013
Zebrafish
response to hydrogen peroxideGO:004254230.013
positive regulation of cell activationGO:005086710.013
negative regulation of wnt signaling pathwayGO:0030178300.013
Zebrafish
locomotor rhythmGO:004547530.013
regulation of nucleotide biosynthetic processGO:0030808150.013
positive regulation of immune effector processGO:000269930.013
reactive nitrogen species metabolic processGO:200105700.013
positive regulation of secretionGO:005104710.012
regulation of cell matrix adhesionGO:000195210.012
positive regulation of secretion by cellGO:190353210.012
adult behaviorGO:003053420.012
regulation of epithelial cell proliferationGO:005067830.012
protein localization to nucleusGO:003450430.012
regulation of neuron differentiationGO:0045664560.012
schwann cell differentiationGO:001403790.012
regulation of rna metabolic processGO:00512522240.012
lymphocyte proliferationGO:004665110.012
cranial nerve developmentGO:0021545420.012
regulation of gtp catabolic processGO:003312420.012
regulation of synapse organizationGO:005080730.012
regulation of macromolecule biosynthetic processGO:00105562250.012
inorganic anion transportGO:0015698250.012
positive regulation of histone modificationGO:003105810.012
regulation of purine nucleotide catabolic processGO:003312120.012
response to abiotic stimulusGO:00096281220.012
regulation of localizationGO:00328791040.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
cytokinesisGO:000091030.012
light induced release of internally sequestered calcium ionGO:000837710.012
macromolecule biosynthetic processGO:00090592270.012
gland developmentGO:00487321430.012
establishment of protein localization to organelleGO:007259440.012
cation transmembrane transportGO:0098655650.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
signal transduction in absence of ligandGO:003803410.012
rhodopsin mediated signaling pathwayGO:001605610.012
negative regulation of protein complex assemblyGO:003133310.012
cellular protein metabolic processGO:00442671290.012
protein secretionGO:000930610.012
positive regulation of catalytic activityGO:0043085250.012
epidermal cell differentiationGO:0009913360.012
leukocyte differentiationGO:0002521250.012
regulation of calcium ion transportGO:005192420.012
cellular lipid catabolic processGO:004424230.012
regionalizationGO:00030022740.011
regulation of sequestering of calcium ionGO:005128240.011
negative regulation of mapk cascadeGO:004340940.011
positive regulation of cellular component biogenesisGO:004408930.011
regulation of dendrite morphogenesisGO:004881430.011
organelle assemblyGO:00709251100.011
Zebrafish
positive regulation of cell matrix adhesionGO:000195410.011
heart developmentGO:00075073130.011
chloride transmembrane transportGO:190247640.011
neuromuscular process controlling balanceGO:005088530.011
peptidyl threonine modificationGO:001821010.011
embryonic retina morphogenesis in camera type eyeGO:0060059220.011
Zebrafish
atp catabolic processGO:000620040.011
positive regulation of cell divisionGO:005178120.011
protein modification processGO:00362111000.011
rna biosynthetic processGO:00327741810.011
cranial ganglion developmentGO:006155030.011
peptidyl serine modificationGO:001820920.011
positive regulation of gliogenesisGO:001401520.011
compound eye developmentGO:004874920.011
muscle organ morphogenesisGO:004864480.011
multi organism processGO:00517041340.011
synaptic vesicle localizationGO:009747910.011
myofibril assemblyGO:0030239480.011
spindle localizationGO:0051653120.011
peptidyl lysine acetylationGO:001839420.011
mesoderm morphogenesisGO:0048332510.011
regulation of cell morphogenesis involved in differentiationGO:0010769380.011
columnar cuboidal epithelial cell differentiationGO:0002065380.011
regulation of nucleoside metabolic processGO:000911820.011
organic acid transportGO:001584990.011
positive regulation of protein complex assemblyGO:003133420.011
regulation of production of molecular mediator of immune responseGO:000270010.011
protein complex localizationGO:003150310.011
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.011
regulation of cell developmentGO:00602841000.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
entrainment of circadian clockGO:000964920.011
mitotic cell cycle processGO:1903047480.011
neural crest cell migrationGO:0001755420.010
regulation of muscle contractionGO:000693730.010
somatic stem cell maintenanceGO:003501910.010
digestive tract mesoderm developmentGO:000750210.010
retina homeostasisGO:0001895120.010
regulation of leukocyte mediated immunityGO:000270310.010
developmental cell growthGO:0048588520.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
regulation of extent of cell growthGO:0061387290.010
regulation of blood vessel sizeGO:005088020.010
regulation of cell activationGO:005086510.010
swim bladder developmentGO:0048794190.010
Zebrafish
oligopeptide transportGO:000685710.010
single organism metabolic processGO:00447102170.010
regulation of lyase activityGO:0051339120.010
protein localization to plasma membraneGO:007265910.010
cellular component disassemblyGO:002241110.010
carboxylic acid transportGO:004694280.010
neural crest cell developmentGO:0014032620.010
anion transmembrane transportGO:0098656120.010

crb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
nervous system diseaseDOID:86300.046
eye and adnexa diseaseDOID:149200.015
sensory system diseaseDOID:005015500.015
inherited metabolic disorderDOID:65500.013
disease of metabolismDOID:001466700.013
eye diseaseDOID:561400.012