Danio rerio

0 known processes

e4f1

E4F transcription factor 1

(Aliases: zgc:114190,MGC114190)

e4f1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of synapse organizationGO:005080730.179
signal transductionGO:00071654550.140
synaptic growth at neuromuscular junctionGO:005112420.139
regulation of synapse assemblyGO:005196330.129
phagocytosisGO:000690930.084
immune system processGO:00023762410.081
modification dependent protein catabolic processGO:001994130.079
cellular component movementGO:00069283350.075
ameboidal type cell migrationGO:00016671430.075
agingGO:000756820.072
cellular protein catabolic processGO:004425740.072
sensory perception of touchGO:005097520.066
guanosine containing compound metabolic processGO:190106840.065
locomotionGO:00400113130.065
proteolysis involved in cellular protein catabolic processGO:005160330.065
positive regulation of cellular catabolic processGO:003133130.064
vasculature developmentGO:00019442780.064
establishment of localizationGO:00512342440.064
generation of neuronsGO:00486993850.061
digestive system developmentGO:00551232890.060
regulation of synaptic growth at neuromuscular junctionGO:000858210.060
morphogenesis of an epitheliumGO:00020093330.059
small molecule metabolic processGO:0044281770.058
cell surface receptor signaling pathwayGO:00071663250.058
axonogenesisGO:00074091520.057
ubiquitin dependent protein catabolic processGO:000651130.056
convergent extensionGO:00600261180.056
cell migrationGO:00164772370.056
regulation of multicellular organism growthGO:004001440.055
cell morphogenesisGO:00009022890.054
larval developmentGO:000216420.054
regulation of multicellular organismal processGO:00512392770.053
Mouse
maintenance of locationGO:005123540.053
modification dependent macromolecule catabolic processGO:004363230.051
multicellular organism growthGO:003526440.051
angiogenesisGO:00015251580.050
muscle cell developmentGO:00550011150.050
cell projection morphogenesisGO:00488582440.049
negative regulation of synapse assemblyGO:005196420.049
organelle organizationGO:00069962270.047
regulation of stem cell proliferationGO:007209120.047
transportGO:00068102200.046
single organism localizationGO:19025782250.045
response to external stimulusGO:00096052640.045
anterior posterior pattern specificationGO:00099521520.045
biosynthetic processGO:00090582940.044
Human Mouse
cellular macromolecule metabolic processGO:00442603910.044
Human Mouse
positive regulation of catabolic processGO:000989640.043
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.043
regulation of signalingGO:00230512350.043
regulation of response to stimulusGO:00485832690.042
stem cell proliferationGO:007208940.041
positive regulation of transportGO:005105020.041
striated muscle cell differentiationGO:00511461290.041
blood vessel morphogenesisGO:00485142160.041
tube morphogenesisGO:00352393490.041
muscle structure developmentGO:00610611960.040
regulation of primary metabolic processGO:00800903110.040
Human
specification of symmetryGO:00097992040.040
regulation of multicellular organismal developmentGO:20000262230.040
Mouse
oxoacid metabolic processGO:0043436310.039
proteasomal protein catabolic processGO:001049820.039
macromolecule biosynthetic processGO:00090592270.039
Human Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.039
Human
response to chemicalGO:00422213200.038
golgi vesicle transportGO:004819330.038
regulation of epithelial cell proliferationGO:005067830.038
gastrulationGO:00073692080.037
regulation of biosynthetic processGO:00098892500.037
Human
regulation of macromolecule biosynthetic processGO:00105562250.036
Human
cellular protein metabolic processGO:00442671290.036
cell part morphogenesisGO:00329902460.036
phagocytosis engulfmentGO:000691110.036
digestive tract developmentGO:00485652650.035
nitrogen compound metabolic processGO:00068073190.035
Human Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.035
cell motilityGO:00488702440.035
skeletal system developmentGO:00015011810.035
regulation of metabolic processGO:00192223590.035
Human
determination of bilateral symmetryGO:00098552040.034
localization of cellGO:00516742440.034
digestive tract morphogenesisGO:00485462310.034
muscle cell differentiationGO:00426921390.034
regulation of establishment of protein localizationGO:007020140.034
regulation of protein targetingGO:190353320.033
macromolecular complex subunit organizationGO:0043933740.033
regulation of bmp signaling pathwayGO:0030510390.033
cell migration involved in gastrulationGO:0042074790.033
blood vessel developmentGO:00015682460.033
cellular component morphogenesisGO:00329893360.033
membrane invaginationGO:001032410.033
stem cell maintenanceGO:001982740.032
organic cyclic compound metabolic processGO:19013603010.032
Human Mouse
regulation of nitrogen compound metabolic processGO:00511712510.032
Human
regulation of cellular biosynthetic processGO:00313262450.031
Human
regulation of bindingGO:005109830.031
translational initiationGO:000641330.031
heterocycle biosynthetic processGO:00181302150.031
Human
heterocycle metabolic processGO:00464832900.031
Human Mouse
protein importGO:001703830.031
sensory organ developmentGO:00074233930.031
sulfur compound metabolic processGO:0006790130.030
protein metabolic processGO:00195381830.030
guanosine containing compound catabolic processGO:190106920.030
gtp metabolic processGO:004603940.030
nucleic acid templated transcriptionGO:00976591810.030
Human
single organism transportGO:00447652060.030
amine metabolic processGO:000930820.030
cellular biosynthetic processGO:00442492860.029
Human Mouse
compound eye developmentGO:004874920.029
cellular ketone metabolic processGO:0042180110.029
hematopoietic or lymphoid organ developmentGO:00485341910.029
regulation of cellular metabolic processGO:00313233200.028
Human
single organism metabolic processGO:00447102170.028
cellular macromolecule biosynthetic processGO:00346452240.028
Human Mouse
establishment of protein localization to organelleGO:007259440.028
organic acid metabolic processGO:0006082310.028
regulation of transcription dna templatedGO:00063552130.028
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.028
extrinsic apoptotic signaling pathwayGO:009719130.028
organonitrogen compound metabolic processGO:1901564740.028
neurotransmitter secretionGO:000726920.027
regulation of cytoplasmic transportGO:190364940.027
protein localization to nucleusGO:003450430.027
positive regulation of cellular component biogenesisGO:004408930.027
regulation of gtp catabolic processGO:003312420.027
protein targeting to nucleusGO:004474430.027
developmental growthGO:00485891660.027
single organism organelle organizationGO:19025891990.027
gtp catabolic processGO:000618420.026
regulation of dendrite morphogenesisGO:004881430.026
cellular response to organic substanceGO:00713101050.026
organic substance biosynthetic processGO:19015762890.026
Human Mouse
regulation of cell communicationGO:00106462320.026
negative regulation of cell communicationGO:0010648960.026
cellular carbohydrate metabolic processGO:004426240.026
negative regulation of biological processGO:00485193040.026
Human
neurotransmitter transportGO:000683620.026
cellular nitrogen compound metabolic processGO:00346412900.026
Human Mouse
regulation of cellular ketone metabolic processGO:001056570.026
determination of left right symmetryGO:00073681790.025
muscle fiber developmentGO:0048747520.025
cellular component assemblyGO:00226071700.025
nucleobase containing compound biosynthetic processGO:00346542050.025
Human
regulation of protein import into nucleusGO:004230620.025
chordate embryonic developmentGO:00430092710.025
regulation of signal transductionGO:00099662250.025
central nervous system developmentGO:00074173870.025
post golgi vesicle mediated transportGO:000689210.025
positive regulation of muscle organ developmentGO:004863610.025
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.024
nucleocytoplasmic transportGO:000691340.024
regulation of cysteine type endopeptidase activityGO:2000116210.024
negative regulation of protein phosphorylationGO:000193340.024
eye developmentGO:00016542770.024
positive regulation of synapse assemblyGO:005196510.024
negative regulation of cellular processGO:00485232830.024
Human
adult behaviorGO:003053420.024
regulation of macromolecule metabolic processGO:00602553170.024
Human
aromatic compound biosynthetic processGO:00194382170.023
Human
nuclear transportGO:005116940.023
somitogenesisGO:0001756870.023
regulation of neurogenesisGO:0050767870.023
regulation of neural precursor cell proliferationGO:200017730.023
regulation of nucleocytoplasmic transportGO:004682220.023
regulation of nucleoside metabolic processGO:000911820.023
meiotic nuclear divisionGO:000712640.023
neuron developmentGO:00486662620.023
regulation of protein bindingGO:004339330.022
autophagyGO:000691440.022
positive regulation of nucleoside metabolic processGO:004597910.022
carbohydrate derivative metabolic processGO:1901135610.022
cellular amino acid metabolic processGO:000652070.022
regulation of localizationGO:00328791040.022
growthGO:00400071740.022
positive regulation of muscle cell differentiationGO:005114910.022
negative regulation of signalingGO:0023057960.022
cilium organizationGO:0044782710.022
regulation of cellular amino acid metabolic processGO:000652100.021
positive regulation of cellular processGO:00485222010.021
cellular amine metabolic processGO:004410620.021
positive regulation of gtp catabolic processGO:003312610.021
response to uvGO:000941130.021
regulation of axonogenesisGO:0050770320.021
embryonic organ developmentGO:00485683810.021
peptidyl serine phosphorylationGO:001810510.021
positive regulation of biological processGO:00485182530.021
regulation of cell morphogenesis involved in differentiationGO:0010769380.021
cell projection organizationGO:00300302840.020
cellular catabolic processGO:0044248270.020
positive regulation of epithelial cell proliferationGO:005067910.020
centrosome organizationGO:005129710.020
axon developmentGO:00615641660.020
regulation of translational initiationGO:000644610.020
protein polyubiquitinationGO:000020940.020
carboxylic acid metabolic processGO:0019752220.020
cytokinetic processGO:003250620.020
regulation of nervous system developmentGO:0051960900.020
female meiotic divisionGO:000714320.020
neuron projection morphogenesisGO:00488121610.020
specification of axis polarityGO:006500140.020
striated muscle tissue developmentGO:00147061100.020
regulation of rna biosynthetic processGO:20011412130.020
Human
neuroblast proliferationGO:000740520.020
convergent extension involved in gastrulationGO:0060027710.020
positive regulation of myeloid cell differentiationGO:004563920.019
spermatid differentiationGO:004851520.019
nucleobase containing compound metabolic processGO:00061392740.019
Human Mouse
germ line stem cell maintenanceGO:003071820.019
striated muscle cell developmentGO:00550021080.019
response to external biotic stimulusGO:0043207970.019
cellular protein modification processGO:00064641000.019
immune system developmentGO:00025201910.019
stem cell divisionGO:001714510.019
meiotic cell cycle processGO:190304630.019
negative regulation of protein kinase activityGO:000646940.019
somite developmentGO:0061053960.019
transcription dna templatedGO:00063511810.019
Human
regulation of peptidase activityGO:0052547230.019
positive regulation of purine nucleotide catabolic processGO:003312310.019
regulation of protein localization to nucleusGO:190018020.019
protein complex localizationGO:003150310.019
regulation of protein catabolic processGO:004217610.019
response to bacteriumGO:0009617580.019
negative regulation of epithelial cell proliferationGO:005068010.019
muscle tissue developmentGO:00605371100.019
taxisGO:00423301090.018
regulation of intracellular protein transportGO:003315730.018
detection of stimulus involved in sensory perceptionGO:0050906210.018
regulation of purine nucleotide catabolic processGO:003312120.018
positive regulation of gtpase activityGO:004354710.018
positive regulation of nucleotide catabolic processGO:003081310.018
regulation of cell shapeGO:000836010.018
cytokinesisGO:000091030.018
rna biosynthetic processGO:00327741810.018
Human
protein import into nucleusGO:000660630.018
cellular component disassemblyGO:002241110.018
neuromuscular synaptic transmissionGO:000727420.018
atp catabolic processGO:000620040.018
cellular response to chemical stimulusGO:00708871570.018
microtubule organizing center organizationGO:003102310.018
sensory organ morphogenesisGO:00905962000.018
system processGO:00030081850.018
microtubule based processGO:0007017600.018
negative regulation of response to stimulusGO:00485851040.018
chemosensory behaviorGO:000763510.018
cellular component biogenesisGO:00440851780.017
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
nucleic acid metabolic processGO:00903042440.017
Human Mouse
cellular response to external stimulusGO:007149620.017
regulation of protein transportGO:005122330.017
cell morphogenesis involved in neuron differentiationGO:00486671630.017
regulation of gtpase activityGO:004308720.017
alcohol biosynthetic processGO:004616520.017
cellular localizationGO:0051641970.017
synaptic transmissionGO:0007268350.017
cell substrate adhesionGO:003158940.017
neuron projection developmentGO:00311751800.016
neuron neuron synaptic transmissionGO:000727010.016
er to golgi vesicle mediated transportGO:000688810.016
regulation of locomotionGO:0040012550.016
dorsal ventral pattern formationGO:00099531250.016
regulation of cell differentiationGO:00455951420.016
cortical actin cytoskeleton organizationGO:003086610.016
carbohydrate derivative biosynthetic processGO:1901137430.016
small gtpase mediated signal transductionGO:000726480.016
neuron differentiationGO:00301823530.016
secondary metabolic processGO:001974830.016
embryo development ending in birth or egg hatchingGO:00097922710.016
positive regulation of striated muscle tissue developmentGO:004584410.016
cilium movementGO:0003341260.016
positive regulation of small gtpase mediated signal transductionGO:005105710.016
protein homooligomerizationGO:005126030.016
regulation of cell developmentGO:00602841000.016
maternal determination of anterior posterior axis embryoGO:000835840.016
regulation of nucleotide catabolic processGO:003081120.016
microtubule based movementGO:0007018330.016
embryonic organ morphogenesisGO:00485622740.016
mitochondrion organizationGO:000700540.016
nuclear migrationGO:000709730.015
protein stabilizationGO:005082120.015
kupffer s vesicle developmentGO:0070121500.015
ribonucleoside monophosphate catabolic processGO:000915840.015
neurological system processGO:0050877620.015
endosomal transportGO:001619720.015
melanin metabolic processGO:000658220.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
oocyte anterior posterior axis specificationGO:000731440.015
response to light stimulusGO:0009416460.015
response to organic substanceGO:00100331530.015
peptide transportGO:001583310.015
spermatid developmentGO:000728620.015
regulation of developmental processGO:00507932470.015
Mouse
negative regulation of defense responseGO:003134820.015
regulation of autophagyGO:001050630.015
positive regulation of neuron apoptotic processGO:004352510.015
response to carbohydrateGO:000974330.015
multi organism processGO:00517041340.015
response to nutrientGO:000758430.015
endosome organizationGO:000703220.015
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.014
cellular response to endogenous stimulusGO:0071495680.014
adherens junction organizationGO:003433240.014
regulation of response to biotic stimulusGO:000283120.014
positive regulation of cell cycleGO:004578730.014
nuclear importGO:005117030.014
mesenchymal cell differentiationGO:0048762870.014
actin polymerization or depolymerizationGO:000815420.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.014
protein localization to plasma membraneGO:007265910.014
regionalizationGO:00030022740.014
synaptic vesicle transportGO:004848910.014
positive regulation of ras gtpase activityGO:003232010.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
proteolysisGO:0006508380.014
regulation of cellular amine metabolic processGO:003323800.014
regulation of erk1 and erk2 cascadeGO:007037240.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
single organism nuclear importGO:190259330.013
i kappab kinase nf kappab signalingGO:000724940.013
regulation of phosphorus metabolic processGO:0051174430.013
histone phosphorylationGO:001657220.013
regulation of dendrite developmentGO:005077330.013
actin filament polymerizationGO:003004120.013
erk1 and erk2 cascadeGO:007037140.013
developmental programmed cell deathGO:001062340.013
regulation of gene expressionGO:00104682650.013
Human
detection of abiotic stimulusGO:0009582240.013
regulation of endopeptidase activityGO:0052548230.013
organic cyclic compound biosynthetic processGO:19013622230.013
Human
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
regulation of biological qualityGO:00650082630.013
regulation of tube sizeGO:003515020.013
positive regulation of secretion by cellGO:190353210.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
regulation of neuron differentiationGO:0045664560.013
nuclear exportGO:005116810.013
organelle fusionGO:004828430.013
synaptic vesicle localizationGO:009747910.013
calcium ion importGO:007050940.013
synapse assemblyGO:000741690.013
sprouting angiogenesisGO:0002040530.013
positive regulation of dna metabolic processGO:005105410.013
regulation of metal ion transportGO:001095940.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
ras protein signal transductionGO:000726570.012
cytoskeleton organizationGO:0007010960.012
detection of external stimulusGO:0009581240.012
mesoderm morphogenesisGO:0048332510.012
negative regulation of signal transductionGO:0009968940.012
sulfur compound biosynthetic processGO:004427290.012
regulation of proteolysisGO:0030162240.012
regulation of molecular functionGO:0065009700.012
cortical cytoskeleton organizationGO:003086510.012
macromolecule modificationGO:00434121110.012
cell cycle g1 s phase transitionGO:004484310.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
Human
regulation of wnt signaling pathwayGO:0030111530.012
phototransductionGO:000760220.012
cellular aromatic compound metabolic processGO:00067252950.012
Human Mouse
positive regulation of developmental processGO:0051094500.012
positive regulation of striated muscle cell differentiationGO:005115510.012
mesenchyme developmentGO:00604851270.012
gene expressionGO:00104672520.012
Human
chemotaxisGO:00069351040.012
bmp signaling pathwayGO:0030509520.012
g1 s transition of mitotic cell cycleGO:000008210.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
regulation of cell activationGO:005086510.012
mitotic cell cycleGO:0000278640.012
Mouse
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
hormone transportGO:000991420.012
organism emergence from protective structureGO:007168440.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
g protein coupled receptor signaling pathwayGO:0007186740.012
protein complex disassemblyGO:004324110.012
defense responseGO:0006952470.012
odontogenesis of dentin containing toothGO:004247510.012
negative regulation of bmp signaling pathwayGO:0030514130.012
somatic muscle developmentGO:000752540.012
protein acetylationGO:000647320.012
cartilage developmentGO:0051216960.012
lipid storageGO:001991510.012
wnt signaling pathwayGO:0016055800.012
glycoprotein metabolic processGO:0009100230.012
negative regulation of intracellular transportGO:003238730.011
protein complex subunit organizationGO:0071822460.011
interspecies interaction between organismsGO:004441940.011
protein modification processGO:00362111000.011
regulation of neuron projection developmentGO:0010975400.011
response to abiotic stimulusGO:00096281220.011
cellular response to radiationGO:007147840.011
epithelial cell morphogenesisGO:000338220.011
response to stressGO:00069502630.011
cognitionGO:005089010.011
cilium morphogenesisGO:0060271850.011
response to growth factorGO:0070848390.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
Human
phototransduction visible lightGO:000760320.011
centrosome cycleGO:000709810.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
myeloid cell differentiationGO:0030099860.011
positive regulation of neuron deathGO:190121610.011
hemopoiesisGO:00300971830.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
regulation of catalytic activityGO:0050790550.011
regulation of receptor activityGO:001046920.011
multi organism cellular processGO:004476420.011
b cell differentiationGO:003018310.011
regulation of developmental growthGO:0048638380.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
regulation of protein ubiquitinationGO:003139630.011
protein modification by small protein removalGO:007064610.011
peptidyl lysine acetylationGO:001839420.011
pronuclear migrationGO:003504610.011
deathGO:00162651210.011
nucleoside monophosphate catabolic processGO:000912540.011
regulation of programmed cell deathGO:00430671010.011
muscle organ developmentGO:00075171010.011
head developmentGO:00603223030.011
heart developmentGO:00075073130.011
regulation of stem cell differentiationGO:200073640.011
negative regulation of macromolecule metabolic processGO:0010605760.011
Human
positive regulation of cytoskeleton organizationGO:005149530.011
membrane fusionGO:006102520.011
negative regulation of kinase activityGO:003367340.011
cardiac muscle tissue developmentGO:0048738480.011
cell morphogenesis involved in differentiationGO:00009041950.011
negative regulation of leukocyte differentiationGO:190210610.011
cellular response to extracellular stimulusGO:003166820.010
glycoprotein biosynthetic processGO:0009101210.010
cell agingGO:000756920.010
negative regulation of multi organism processGO:004390130.010
peptidyl serine modificationGO:001820920.010
locomotor rhythmGO:004547530.010
single organism membrane fusionGO:004480120.010
connective tissue developmentGO:0061448990.010
organelle assemblyGO:00709251100.010
positive regulation of muscle tissue developmentGO:190186310.010
brain developmentGO:00074202930.010
rna metabolic processGO:00160702190.010
Human
embryonic limb morphogenesisGO:003032620.010
cellular response to lipopolysaccharideGO:007122230.010
establishment of synaptic vesicle localizationGO:009748010.010
determination of left right asymmetry in nervous systemGO:003554540.010
sequestering of calcium ionGO:005120830.010
cellular response to biotic stimulusGO:007121630.010
regulation of protein complex disassemblyGO:004324410.010
left right pattern formationGO:0060972190.010
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.010
sensory perceptionGO:0007600390.010
macromolecular complex assemblyGO:0065003350.010
pathway restricted smad protein phosphorylationGO:006038910.010
negative regulation of cytoplasmic transportGO:190365020.010
positive regulation of cellular amine metabolic processGO:003324000.010
regulation of cell morphogenesisGO:0022604420.010

e4f1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
nervous system diseaseDOID:86300.038
neurodegenerative diseaseDOID:128900.012
central nervous system diseaseDOID:33100.012
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011
eye diseaseDOID:561400.011