Danio rerio

43 known processes

nkd2

naked cuticle homolog 2 and naked 2a

(Aliases: nkd2a,nkd2b,nkd2l)

nkd2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
bmp signaling pathwayGO:0030509520.731
tube morphogenesisGO:00352393490.622
regulation of nitrogen compound metabolic processGO:00511712510.509
regulation of rna metabolic processGO:00512522240.509
cell migration involved in gastrulationGO:0042074790.502
gastrulationGO:00073692080.467
digestive tract morphogenesisGO:00485462310.435
regulation of developmental processGO:00507932470.413
regulation of macromolecule metabolic processGO:00602553170.367
determination of bilateral symmetryGO:00098552040.347
digestive tract developmentGO:00485652650.345
heterocycle biosynthetic processGO:00181302150.335
kupffer s vesicle developmentGO:0070121500.295
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.270
nitrogen compound metabolic processGO:00068073190.265
cellular component movementGO:00069283350.260
regulation of nucleic acid templated transcriptionGO:19035062130.250
organic cyclic compound metabolic processGO:19013603010.245
heart developmentGO:00075073130.243
transcription dna templatedGO:00063511810.224
locomotionGO:00400113130.220
specification of symmetryGO:00097992040.217
cell migrationGO:00164772370.213
regulation of cell communicationGO:00106462320.209
morphogenesis of an epitheliumGO:00020093330.193
organic substance biosynthetic processGO:19015762890.190
cell surface receptor signaling pathwayGO:00071663250.184
organic cyclic compound biosynthetic processGO:19013622230.183
digestive system developmentGO:00551232890.180
response to chemicalGO:00422213200.177
regulation of rna biosynthetic processGO:20011412130.174
positive regulation of catabolic processGO:000989640.172
agingGO:000756820.168
localization of cellGO:00516742440.162
developmental growth involved in morphogenesisGO:0060560860.160
signal transductionGO:00071654550.156
negative regulation of signal transductionGO:0009968940.156
negative regulation of cellular processGO:00485232830.153
regulation of gene expressionGO:00104682650.152
convergent extensionGO:00600261180.152
determination of heart left right asymmetryGO:00613711170.146
response to drugGO:004249330.144
macromolecule biosynthetic processGO:00090592270.139
immune system processGO:00023762410.134
regulation of signal transductionGO:00099662250.133
aromatic compound biosynthetic processGO:00194382170.132
regulation of synapse organizationGO:005080730.131
regulation of response to stimulusGO:00485832690.128
regulation of cellular metabolic processGO:00313233200.123
cellular aromatic compound metabolic processGO:00067252950.119
chemotaxisGO:00069351040.119
ameboidal type cell migrationGO:00016671430.114
rna biosynthetic processGO:00327741810.109
cellular nitrogen compound metabolic processGO:00346412900.106
larval developmentGO:000216420.103
embryonic heart tube developmentGO:00350501330.102
regulation of cellular biosynthetic processGO:00313262450.102
negative regulation of response to stimulusGO:00485851040.101
regulation of macromolecule biosynthetic processGO:00105562250.099
positive regulation of transportGO:005105020.098
nucleic acid metabolic processGO:00903042440.094
heart morphogenesisGO:00030071560.094
anterior posterior pattern specificationGO:00099521520.093
regulation of cell differentiationGO:00455951420.093
regulation of cellular macromolecule biosynthetic processGO:20001122220.091
heterocycle metabolic processGO:00464832900.091
determination of left right symmetryGO:00073681790.088
anterior posterior axis specificationGO:0009948200.085
negative regulation of signalingGO:0023057960.085
taxisGO:00423301090.083
embryonic heart tube morphogenesisGO:00031431080.082
regionalizationGO:00030022740.081
heart joggingGO:0003146400.079
positive regulation of response to stimulusGO:0048584800.079
cellular biosynthetic processGO:00442492860.078
cellular macromolecule biosynthetic processGO:00346452240.076
nucleobase containing compound metabolic processGO:00061392740.076
regulation of primary metabolic processGO:00800903110.073
nucleobase containing compound biosynthetic processGO:00346542050.072
negative regulation of biological processGO:00485193040.072
nucleic acid templated transcriptionGO:00976591810.070
head developmentGO:00603223030.069
regulation of synapse assemblyGO:005196330.069
cell motilityGO:00488702440.068
regulation of locomotionGO:0040012550.066
cellular response to chemical stimulusGO:00708871570.066
regulation of nucleobase containing compound metabolic processGO:00192192500.066
regulation of biosynthetic processGO:00098892500.065
immune system developmentGO:00025201910.065
convergent extension involved in organogenesisGO:0060029100.065
gland developmentGO:00487321430.064
regulation of signalingGO:00230512350.064
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.061
regulation of chemotaxisGO:0050920180.061
regulation of transcription from rna polymerase ii promoterGO:00063571140.058
vacuolar transportGO:000703420.056
regulation of ectodermal cell fate specificationGO:004266520.056
striated muscle cell developmentGO:00550021080.055
spemann organizer formationGO:0060061100.055
cellular macromolecule metabolic processGO:00442603910.054
dorsal convergenceGO:0060030140.052
axis elongationGO:0003401310.052
positive regulation of cellular catabolic processGO:003133130.052
guanosine containing compound catabolic processGO:190106920.051
regulation of axonogenesisGO:0050770320.048
oocyte maturationGO:000155640.047
axon extensionGO:0048675450.046
negative regulation of synapse assemblyGO:005196420.046
synaptic growth at neuromuscular junctionGO:005112420.045
brain developmentGO:00074202930.045
maintenance of locationGO:005123540.044
mesoderm developmentGO:0007498880.044
determination of ventral identityGO:0048264210.043
biosynthetic processGO:00090582940.042
cellular nitrogen compound biosynthetic processGO:00442712180.042
regulation of calcium dependent cell cell adhesionGO:004658610.042
regulation of axon extensionGO:0030516240.042
positive regulation of biological processGO:00485182530.042
optic placode formationGO:000174340.041
negative regulation of protein complex assemblyGO:003133310.040
regulation of metabolic processGO:00192223590.040
protein complex assemblyGO:0006461300.040
rna metabolic processGO:00160702190.040
gene expressionGO:00104672520.039
regulation of biological qualityGO:00650082630.039
muscle fiber developmentGO:0048747520.038
cellular component morphogenesisGO:00329893360.037
response to organic substanceGO:00100331530.037
spinal cord anterior posterior patterningGO:002151210.036
regulation of mesoderm developmentGO:2000380110.036
hormone transportGO:000991420.036
formation of primary germ layerGO:0001704620.035
cellular component disassemblyGO:002241110.034
mesenchyme developmentGO:00604851270.034
ear morphogenesisGO:0042471640.034
embryonic organ developmentGO:00485683810.034
response to glucocorticoidGO:005138410.033
eye morphogenesisGO:00485921440.033
convergent extension involved in gastrulationGO:0060027710.033
single organism transportGO:00447652060.033
dorsal ventral pattern formationGO:00099531250.033
negative regulation of cell communicationGO:0010648960.033
transcription from rna polymerase ii promoterGO:0006366800.033
regulation of multicellular organismal processGO:00512392770.032
regulation of cellular component organizationGO:0051128860.032
multicellular organism growthGO:003526440.032
regulation of meiotic cell cycleGO:005144510.032
regulation of metal ion transportGO:001095940.032
sensory organ developmentGO:00074233930.032
negative regulation of behaviorGO:004852160.031
regulation of multicellular organismal developmentGO:20000262230.031
negative regulation of mesodermal cell fate specificationGO:004266230.031
programmed cell deathGO:00125011190.031
wnt signaling pathway planar cell polarity pathwayGO:006007140.031
cell projection morphogenesisGO:00488582440.029
single organism localizationGO:19025782250.029
chordate embryonic developmentGO:00430092710.029
negative regulation of axon extension involved in axon guidanceGO:004884310.029
hematopoietic or lymphoid organ developmentGO:00485341910.029
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.028
enzyme linked receptor protein signaling pathwayGO:00071671060.028
regulation of sequestering of calcium ionGO:005128240.028
generation of neuronsGO:00486993850.027
muscle cell migrationGO:001481240.027
regulation of protein complex assemblyGO:004325430.027
g1 s transition of mitotic cell cycleGO:000008210.027
epithelial cell differentiationGO:00308551160.026
establishment of organelle localizationGO:0051656450.026
regulation of programmed cell deathGO:00430671010.026
cellular protein metabolic processGO:00442671290.026
regulation of protein transportGO:005122330.026
single organism metabolic processGO:00447102170.026
cell projection organizationGO:00300302840.026
organonitrogen compound metabolic processGO:1901564740.026
macromolecular complex disassemblyGO:003298410.026
regulation of developmental growthGO:0048638380.025
nuclear importGO:005117030.025
cellular protein modification processGO:00064641000.025
cellular component assemblyGO:00226071700.025
developmental growthGO:00485891660.025
stem cell maintenanceGO:001982740.025
cation homeostasisGO:0055080330.025
regulation of protein localization to nucleusGO:190018020.025
regulation of cellular component movementGO:0051270550.025
hematopoietic stem cell differentiationGO:0060218200.025
homeostatic processGO:00425921420.024
oocyte anterior posterior axis specificationGO:000731440.024
cell fate commitmentGO:0045165990.024
positive regulation of secretionGO:005104710.024
cellular response to fibroblast growth factor stimulusGO:0044344220.024
regulation of cell deathGO:00109411030.024
sensory organ morphogenesisGO:00905962000.024
otic vesicle developmentGO:0071599420.024
metencephalon developmentGO:0022037270.024
regulation of bmp signaling pathwayGO:0030510390.024
regulation of intracellular protein transportGO:003315730.024
regulation of nucleoside metabolic processGO:000911820.023
leukocyte homeostasisGO:000177620.023
protein complex subunit organizationGO:0071822460.023
lateral line developmentGO:0048882660.023
granulocyte migrationGO:0097530110.023
negative chemotaxisGO:005091910.023
digestive tract mesoderm developmentGO:000750210.023
cranial ganglion developmentGO:006155030.022
regulation of establishment of protein localizationGO:007020140.022
cell growthGO:0016049570.022
glial cell differentiationGO:0010001420.022
negative regulation of nuclear divisionGO:005178430.022
somatic stem cell maintenanceGO:003501910.022
central nervous system developmentGO:00074173870.022
regulation of cell sizeGO:0008361290.022
eye developmentGO:00016542770.022
regulation of tube sizeGO:003515020.022
pigment granule localizationGO:0051875250.022
determination of left right asymmetry in diencephalonGO:003546240.022
lymphocyte homeostasisGO:000226010.022
establishment of protein localization to plasma membraneGO:009000210.021
guanosine containing compound metabolic processGO:190106840.021
regulation of bmp signaling pathway involved in heart joggingGO:2000223120.021
positive regulation of cell adhesionGO:004578510.021
cell morphogenesis involved in differentiationGO:00009041950.021
chemical homeostasisGO:0048878490.021
peptidyl lysine monomethylationGO:001802610.021
protein dephosphorylationGO:000647030.021
response to corticosteroidGO:003196010.021
macromolecule methylationGO:0043414190.021
sequestering of metal ionGO:005123830.021
mesoderm morphogenesisGO:0048332510.020
inner ear developmentGO:00488391260.020
carbohydrate homeostasisGO:003350010.020
regulation of cell morphogenesis involved in differentiationGO:0010769380.020
central nervous system neuron axonogenesisGO:0021955180.020
locomotory behaviorGO:0007626340.020
olfactory lobe developmentGO:002198840.020
sensory system developmentGO:0048880760.020
phosphorus metabolic processGO:00067931090.020
defense response to other organismGO:0098542330.019
negative regulation of cellular component organizationGO:0051129160.019
response to hexoseGO:000974630.019
g protein coupled receptor signaling pathwayGO:0007186740.019
cytokinesisGO:000091030.019
establishment of localizationGO:00512342440.019
cellular chemical homeostasisGO:0055082170.019
regulation of localizationGO:00328791040.019
response to alcoholGO:0097305140.019
regulation of immune responseGO:0050776140.019
response to fluid shear stressGO:003440520.019
protein modification processGO:00362111000.019
small molecule metabolic processGO:0044281770.019
regulation of muscle contractionGO:000693730.019
positive regulation of rna metabolic processGO:0051254590.019
neuron differentiationGO:00301823530.018
regulation of cellular component sizeGO:0032535300.018
positive regulation of cytokine productionGO:000181920.018
regulation of reproductive processGO:200024140.018
cell part morphogenesisGO:00329902460.018
cell cell signalingGO:0007267520.018
angiogenesisGO:00015251580.018
regulation of wnt signaling pathway planar cell polarity pathwayGO:200009520.018
fin developmentGO:0033333770.018
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.018
zinc ion transportGO:000682920.018
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.018
regulation of bindingGO:005109830.018
positive regulation of signal transductionGO:0009967560.018
regulation of immune system processGO:0002682340.018
regulation of axon guidanceGO:190266780.018
anterior head developmentGO:009706520.018
regulation of purine nucleotide catabolic processGO:003312120.018
protein metabolic processGO:00195381830.018
positive regulation of gtpase activityGO:004354710.018
protein importGO:001703830.018
regulation of axon extension involved in axon guidanceGO:004884160.018
response to glucoseGO:000974930.018
female meiotic divisionGO:000714320.018
camera type eye developmentGO:00430102220.018
negative regulation of programmed cell deathGO:0043069580.018
liver developmentGO:0001889960.017
positive regulation of cellular component biogenesisGO:004408930.017
determination of dorsal ventral asymmetryGO:0048262340.017
regulation of cell developmentGO:00602841000.017
macromolecular complex subunit organizationGO:0043933740.017
cell cycle arrestGO:000705010.017
melanosome transportGO:0032402190.017
developmental inductionGO:0031128100.017
pectoral fin morphogenesisGO:0035138290.017
developmental cell growthGO:0048588520.017
multicellular organismal signalingGO:0035637220.016
negative regulation of calcium dependent cell cell adhesionGO:004658810.016
protein complex disassemblyGO:004324110.016
negative regulation of anterior neural cell fate commitment of the neural plateGO:002200110.016
erythrocyte homeostasisGO:0034101550.016
negative regulation of myeloid leukocyte differentiationGO:000276210.016
positive regulation of gtp catabolic processGO:003312610.016
regulation of multicellular organism growthGO:004001440.016
pectoral fin developmentGO:0033339500.016
cellular protein complex disassemblyGO:004362410.016
phosphate containing compound metabolic processGO:00067961080.016
regulation of protein metabolic processGO:0051246560.016
peptidyl lysine methylationGO:001802230.016
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.016
centrosome cycleGO:000709810.016
eye photoreceptor cell differentiationGO:0001754450.016
homeostasis of number of cellsGO:0048872620.016
regulation of extent of cell growthGO:0061387290.016
ectodermal placode morphogenesisGO:0071697320.015
protein polyubiquitinationGO:000020940.015
central nervous system neuron differentiationGO:0021953740.015
positive regulation of nucleotide catabolic processGO:003081310.015
macromolecular complex assemblyGO:0065003350.015
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.015
positive regulation of dna metabolic processGO:005105410.015
glucose homeostasisGO:004259310.015
negative regulation of macromolecule metabolic processGO:0010605760.015
deathGO:00162651210.015
single organism organelle organizationGO:19025891990.015
hepaticobiliary system developmentGO:0061008980.015
somatic muscle developmentGO:000752540.015
negative regulation of reproductive processGO:200024230.015
negative regulation of translationGO:001714810.015
striated muscle tissue developmentGO:00147061100.015
negative regulation of cell deathGO:0060548600.015
embryonic camera type eye formationGO:0060900100.015
regulation of response to external stimulusGO:0032101310.015
cell cycle g1 s phase transitionGO:004484310.015
rna 3 end processingGO:003112320.015
embryonic organ morphogenesisGO:00485622740.014
hemopoiesisGO:00300971830.014
organ formationGO:0048645170.014
embryonic hemopoiesisGO:0035162530.014
histone h4 k20 methylationGO:003477020.014
epibolyGO:0090504410.014
endosomal transportGO:001619720.014
muscle cell differentiationGO:00426921390.014
negative regulation of defense responseGO:003134820.014
cellular localizationGO:0051641970.014
fin morphogenesisGO:0033334530.014
positive regulation of secretion by cellGO:190353210.014
regulation of anterior head developmentGO:200074220.014
response to external stimulusGO:00096052640.014
negative regulation of locomotionGO:0040013180.014
neural tube developmentGO:0021915620.014
otic placode formationGO:0043049230.014
establishment of protein localization to organelleGO:007259440.014
negative regulation of leukocyte migrationGO:000268630.014
protein depolymerizationGO:005126110.014
regulation of gastrulationGO:0010470240.014
atp catabolic processGO:000620040.014
heart loopingGO:0001947940.014
regulation of cellular amine metabolic processGO:003323800.013
embryonic neurocranium morphogenesisGO:0048702150.013
regulation of protein import into nucleusGO:004230620.013
cell death in response to oxidative stressGO:003647320.013
response to uvGO:000941130.013
muscle cell developmentGO:00550011150.013
inner ear morphogenesisGO:0042472630.013
myeloid leukocyte migrationGO:0097529120.013
regulation of reactive oxygen species metabolic processGO:200037720.013
specification of axis polarityGO:006500140.013
endodermal cell fate determinationGO:000749320.013
specification of organ positionGO:001015930.013
pathway restricted smad protein phosphorylationGO:006038910.013
heart formationGO:0060914130.013
female sex differentiationGO:004666040.013
regulation of protein catabolic processGO:004217610.013
single organism cellular localizationGO:1902580460.013
myeloid cell homeostasisGO:0002262560.013
endothelial cell fate commitmentGO:006083930.013
sister chromatid cohesionGO:000706220.013
regulation of cytokine productionGO:000181730.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
histone lysine methylationGO:0034968120.013
cell cycle processGO:0022402530.013
pigment granule transportGO:0051904190.013
pons developmentGO:0021548110.013
endocardial cushion morphogenesisGO:000320330.013
negative regulation of metabolic processGO:0009892860.013
regulation of ras gtpase activityGO:003231820.013
meiotic cell cycle processGO:190304630.013
gtp catabolic processGO:000618420.013
camera type eye morphogenesisGO:00485931080.013
cellular component biogenesisGO:00440851780.013
response to monosaccharideGO:003428430.013
regulation of blood vessel sizeGO:005088020.013
positive regulation of cell communicationGO:0010647560.013
regulation of dna recombinationGO:000001820.013
system processGO:00030081850.013
biological adhesionGO:0022610400.013
nephron epithelium morphogenesisGO:007208810.013
negative regulation of cell fate commitmentGO:0010454130.013
cell morphogenesisGO:00009022890.012
regulation of cell maturationGO:190342910.012
catenin import into nucleusGO:003541120.012
positive regulation of cell cycleGO:004578730.012
epithelial tube morphogenesisGO:00605621480.012
somitogenesisGO:0001756870.012
regulation of cell migrationGO:0030334400.012
outflow tract morphogenesisGO:000315110.012
regulation of anatomical structure morphogenesisGO:00226031300.012
negative regulation of multicellular organismal processGO:0051241690.012
eye field cell fate commitment involved in camera type eye formationGO:006089830.012
regulation of cytoplasmic transportGO:190364940.012
neural plate regionalizationGO:0060897100.012
mediolateral intercalationGO:006003130.012
regulation of gtpase activityGO:004308720.012
axonogenesisGO:00074091520.012
tissue regenerationGO:0042246740.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
regulation of response to oxidative stressGO:190288220.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.012
positive regulation of signalingGO:0023056560.012
mrna processingGO:0006397140.012
regulation of embryonic developmentGO:0045995470.012
ectodermal placode developmentGO:0071696370.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
humoral immune response mediated by circulating immunoglobulinGO:000245530.011
regulation of cell projection organizationGO:0031344440.011
protein acylationGO:004354330.011
regulation of transcription dna templatedGO:00063552130.011
neuron developmentGO:00486662620.011
positive regulation of immune responseGO:0050778110.011
cellular transition metal ion homeostasisGO:004691630.011
regulation of establishment of planar polarityGO:009017540.011
spindle assembly involved in mitosisGO:009030710.011
positive regulation of multi organism processGO:004390230.011
response to metal ionGO:0010038340.011
mesoderm formationGO:0001707430.011
carbohydrate derivative metabolic processGO:1901135610.011
gene silencingGO:001645840.011
regulation of endocrine processGO:004406020.011
female gonad developmentGO:000858540.011
ion homeostasisGO:0050801410.011
macromolecule modificationGO:00434121110.011
positive regulation of cell activationGO:005086710.011
regulation of cell motilityGO:2000145460.011
regulation of cell cell adhesionGO:0022407130.011
negative regulation of apoptotic processGO:0043066550.011
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.011
wnt signaling pathwayGO:0016055800.011
hormone secretionGO:004687920.011
central nervous system formationGO:002155610.011
g2 m transition of mitotic cell cycleGO:000008640.011
regulation of bone remodelingGO:004685020.011
behaviorGO:0007610740.011
lateral line system developmentGO:0048925760.011
epidermal cell differentiationGO:0009913360.011
embryonic digestive tract morphogenesisGO:004855730.011
blood circulationGO:0008015870.011
negative regulation of intracellular transportGO:003238730.011
cardiac atrium developmentGO:000323040.011
protein homooligomerizationGO:005126030.011
regulation of cell growthGO:0001558290.011
regulation of protein targetingGO:190353320.011
fibroblast growth factor receptor signaling pathwayGO:0008543220.011
hepatic duct developmentGO:006101120.011
tissue remodelingGO:004877140.011
ion transportGO:00068111140.011
positive regulation of muscle organ developmentGO:004863610.010
organelle organizationGO:00069962270.010
regulation of cell activationGO:005086510.010
neuron projection extensionGO:1990138450.010
microtubule cytoskeleton organization involved in mitosisGO:190285010.010
lytic vacuole organizationGO:008017110.010
homologous chromosome segregationGO:004514310.010
cytokinetic processGO:003250620.010
regulation of nucleocytoplasmic transportGO:004682220.010
regulation of apoptotic processGO:0042981980.010
regulation of catenin import into nucleusGO:003541220.010
retina development in camera type eyeGO:00600411460.010
regulation of cellular amino acid metabolic processGO:000652100.010
peptidyl threonine phosphorylationGO:001810710.010
cellular response to stressGO:0033554620.010
single organism reproductive processGO:0044702400.010

nkd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.061
amyotrophic lateral sclerosisDOID:33200.026
central nervous system diseaseDOID:33100.026
nervous system diseaseDOID:86300.026
motor neuron diseaseDOID:23100.026
neurodegenerative diseaseDOID:128900.026
disease of cellular proliferationDOID:1456600.011