Danio rerio

44 known processes

otpa

orthopedia homolog a

otpa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
diencephalon developmentGO:0021536580.998
forebrain developmentGO:0030900960.996
generation of neuronsGO:00486993850.986
response to external stimulusGO:00096052640.976
aromatic compound biosynthetic processGO:00194382170.976
nitrogen compound metabolic processGO:00068073190.974
organic cyclic compound biosynthetic processGO:19013622230.966
positive regulation of cellular processGO:00485222010.961
cellular biosynthetic processGO:00442492860.959
brain developmentGO:00074202930.958
signal transductionGO:00071654550.945
organic substance biosynthetic processGO:19015762890.938
cellular macromolecule metabolic processGO:00442603910.937
response to chemicalGO:00422213200.925
nucleobase containing compound biosynthetic processGO:00346542050.925
cellular aromatic compound metabolic processGO:00067252950.923
heterocycle metabolic processGO:00464832900.901
organic cyclic compound metabolic processGO:19013603010.894
heterocycle biosynthetic processGO:00181302150.887
nucleobase containing compound metabolic processGO:00061392740.872
biosynthetic processGO:00090582940.871
regulation of nitrogen compound metabolic processGO:00511712510.847
regulation of biosynthetic processGO:00098892500.838
regulation of biological qualityGO:00650082630.830
cellular macromolecule biosynthetic processGO:00346452240.819
regulation of nucleobase containing compound metabolic processGO:00192192500.802
cellular nitrogen compound metabolic processGO:00346412900.798
regulation of cellular biosynthetic processGO:00313262450.796
positive regulation of macromolecule metabolic processGO:0010604930.795
response to organic substanceGO:00100331530.787
macromolecule biosynthetic processGO:00090592270.778
cellular nitrogen compound biosynthetic processGO:00442712180.774
limbic system developmentGO:0021761160.763
regulation of cellular metabolic processGO:00313233200.762
regulation of metabolic processGO:00192223590.758
positive regulation of biological processGO:00485182530.734
response to stressGO:00069502630.724
regulation of signalingGO:00230512350.713
regulation of primary metabolic processGO:00800903110.710
cognitionGO:005089010.710
positive regulation of cellular biosynthetic processGO:0031328680.675
regulation of multicellular organismal processGO:00512392770.670
hematopoietic or lymphoid organ developmentGO:00485341910.666
hypothalamus developmentGO:0021854140.665
Zebrafish
neuron projection developmentGO:00311751800.664
nucleic acid templated transcriptionGO:00976591810.648
positive regulation of metabolic processGO:00098931080.637
behaviorGO:0007610740.637
single organism metabolic processGO:00447102170.635
regulation of response to stimulusGO:00485832690.634
cell surface receptor signaling pathwayGO:00071663250.623
neuron projection extensionGO:1990138450.622
positive regulation of signal transductionGO:0009967560.617
cellular response to organic substanceGO:00713101050.597
single organism localizationGO:19025782250.593
regulation of macromolecule biosynthetic processGO:00105562250.591
locomotionGO:00400113130.585
regulation of cellular macromolecule biosynthetic processGO:20001122220.582
head developmentGO:00603223030.574
positive regulation of cellular metabolic processGO:0031325940.568
multicellular organism reproductionGO:0032504350.534
cellular component movementGO:00069283350.532
positive regulation of nitrogen compound metabolic processGO:0051173690.531
gabaergic neuron differentiationGO:009715420.526
positive regulation of biosynthetic processGO:0009891680.525
neuron differentiationGO:00301823530.518
taxisGO:00423301090.514
nucleotide metabolic processGO:0009117280.507
transportGO:00068102200.506
cell motilityGO:00488702440.492
small molecule metabolic processGO:0044281770.491
spinal cord developmentGO:0021510460.474
neuron neuron synaptic transmissionGO:000727010.473
chemotaxisGO:00069351040.473
rna biosynthetic processGO:00327741810.467
response to abiotic stimulusGO:00096281220.462
negative regulation of response to stimulusGO:00485851040.432
cell cell signalingGO:0007267520.432
Fly
positive regulation of macromolecule biosynthetic processGO:0010557590.426
regulation of phosphorus metabolic processGO:0051174430.423
endocrine system developmentGO:0035270650.421
nucleic acid metabolic processGO:00903042440.419
cell fate commitmentGO:0045165990.416
Fly
central nervous system developmentGO:00074173870.410
transcription dna templatedGO:00063511810.401
negative regulation of cellular processGO:00485232830.400
regulation of gene expressionGO:00104682650.400
regulation of response to nutrient levelsGO:003210710.398
regulation of cell communicationGO:00106462320.397
regulation of neurogenesisGO:0050767870.375
positive regulation of rna biosynthetic processGO:1902680570.364
gene expressionGO:00104672520.356
intracellular signal transductionGO:0035556850.355
regulation of macromolecule metabolic processGO:00602553170.354
positive regulation of gene expressionGO:0010628710.349
apoptotic processGO:00069151160.348
negative regulation of biological processGO:00485193040.348
response to foodGO:003209410.339
regulation of rna metabolic processGO:00512522240.333
regulation of signal transductionGO:00099662250.323
carbohydrate derivative metabolic processGO:1901135610.322
regulation of transcription dna templatedGO:00063552130.319
positive regulation of rna metabolic processGO:0051254590.318
programmed cell deathGO:00125011190.311
multicellular organismal response to stressGO:003355520.305
negative regulation of signal transductionGO:0009968940.290
catecholamine metabolic processGO:000658420.281
neuron fate commitmentGO:0048663260.279
negative regulation of signalingGO:0023057960.277
negative regulation of cell communicationGO:0010648960.270
cell deathGO:00082191210.270
organonitrogen compound metabolic processGO:1901564740.269
cell fate specificationGO:0001708680.265
neuron developmentGO:00486662620.261
adult behaviorGO:003053420.255
cell differentiation in spinal cordGO:0021515400.251
central nervous system neuron differentiationGO:0021953740.244
hypothalamus cell differentiationGO:002197940.241
cyclic nucleotide metabolic processGO:0009187180.240
regulation of cell deathGO:00109411030.240
skeletal system developmentGO:00015011810.236
positive regulation of response to stimulusGO:0048584800.229
regulation of camp metabolic processGO:003081490.228
cellular response to chemical stimulusGO:00708871570.218
regulation of multicellular organismal developmentGO:20000262230.215
regulation of rna biosynthetic processGO:20011412130.214
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:000718850.213
positive regulation of nucleobase containing compound metabolic processGO:0045935690.213
closure of optic fissureGO:006138660.210
phosphate containing compound metabolic processGO:00067961080.207
homeostatic processGO:00425921420.202
cellular response to endogenous stimulusGO:0071495680.200
positive regulation of cell communicationGO:0010647560.200
regulation of developmental processGO:00507932470.198
regulation of synapse assemblyGO:005196330.189
serotonin metabolic processGO:004242810.188
habenula developmentGO:002198690.177
localization of cellGO:00516742440.174
regulation of immune system processGO:0002682340.169
catechol containing compound metabolic processGO:000971220.169
neuron projection guidanceGO:0097485860.166
membrane hyperpolarizationGO:006008110.166
pancreatic a cell developmentGO:000332220.166
regulation of nervous system developmentGO:0051960900.161
adenohypophysis developmentGO:0021984150.160
primary amino compound metabolic processGO:190116010.157
response to hormoneGO:0009725480.155
axonogenesisGO:00074091520.155
primary amino compound biosynthetic processGO:190116210.154
digestive system developmentGO:00551232890.153
locomotory behaviorGO:0007626340.152
stem cell maintenanceGO:001982740.152
axon extensionGO:0048675450.150
nucleobase containing small molecule metabolic processGO:0055086320.149
immune system processGO:00023762410.145
olfactory bulb developmentGO:002177240.142
regulation of cell differentiationGO:00455951420.142
reproductive processGO:0022414400.139
hemopoiesisGO:00300971830.139
response to oxygen containing compoundGO:1901700550.138
axon guidanceGO:0007411860.138
regulation of molecular functionGO:0065009700.137
steroid hormone mediated signaling pathwayGO:004340190.135
phosphorus metabolic processGO:00067931090.133
negative regulation of cellular metabolic processGO:0031324770.133
single organism biosynthetic processGO:0044711710.132
transcription from rna polymerase ii promoterGO:0006366800.131
regulation of postsynaptic membrane potentialGO:006007810.130
muscle structure developmentGO:00610611960.130
positive regulation of nucleic acid templated transcriptionGO:1903508570.130
establishment of localizationGO:00512342440.130
regulation of transcription from rna polymerase ii promoterGO:00063571140.129
cellular response to organic cyclic compoundGO:0071407380.127
response to woundingGO:00096111160.126
establishment of localization in cellGO:0051649770.125
negative regulation of nucleobase containing compound metabolic processGO:0045934590.124
deathGO:00162651210.123
cell morphogenesis involved in neuron differentiationGO:00486671630.121
rna metabolic processGO:00160702190.119
positive regulation of cell proliferationGO:0008284150.118
negative regulation of secretionGO:005104820.117
response to endogenous stimulusGO:0009719830.116
regulation of intracellular signal transductionGO:1902531570.113
cellular component morphogenesisGO:00329893360.112
organelle organizationGO:00069962270.112
response to steroid hormoneGO:0048545350.111
cell growthGO:0016049570.110
neuron projection morphogenesisGO:00488121610.110
regulation of localizationGO:00328791040.108
response to lipidGO:0033993600.107
response to amineGO:001407510.106
negative regulation of nitrogen compound metabolic processGO:0051172590.106
cell part morphogenesisGO:00329902460.105
positive regulation of signalingGO:0023056560.104
growthGO:00400071740.103
sensory perceptionGO:0007600390.102
pigment granule localizationGO:0051875250.101
neutrophil migrationGO:1990266100.101
rhythmic processGO:0048511210.101
synaptic transmissionGO:0007268350.100
positive regulation of transcription dna templatedGO:0045893570.098
response to nitrogen compoundGO:1901698190.095
positive regulation of protein metabolic processGO:0051247230.095
developmental growth involved in morphogenesisGO:0060560860.095
catechol containing compound biosynthetic processGO:000971320.093
regulation of catalytic activityGO:0050790550.093
regulation of camp biosynthetic processGO:003081790.092
regulation of locomotionGO:0040012550.092
indole containing compound metabolic processGO:004243020.090
response to drugGO:004249330.089
positive regulation of camp biosynthetic processGO:003081920.089
multicellular organism growthGO:003526440.086
cellular response to external stimulusGO:007149620.086
developmental cell growthGO:0048588520.084
positive regulation of catalytic activityGO:0043085250.084
organonitrogen compound biosynthetic processGO:1901566470.084
response to inorganic substanceGO:0010035380.084
cellular response to lipidGO:0071396390.083
positive regulation of cellular catabolic processGO:003133130.083
system processGO:00030081850.082
regulation of phosphate metabolic processGO:0019220430.081
nitrogen compound transportGO:0071705230.080
regulation of nucleotide metabolic processGO:0006140170.079
negative regulation of metabolic processGO:0009892860.078
regulation of nucleic acid templated transcriptionGO:19035062130.078
calcium ion transport into cytosolGO:006040230.077
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.077
response to amphetamineGO:000197510.076
mechanosensory behaviorGO:000763820.076
regulation of cellular response to growth factor stimulusGO:0090287350.076
regulation of neuron differentiationGO:0045664560.075
neuron deathGO:0070997210.075
gland developmentGO:00487321430.075
axon developmentGO:00615641660.074
cellular response to hormone stimulusGO:0032870390.074
regulation of blood circulationGO:1903522320.073
ribose phosphate biosynthetic processGO:0046390200.071
pancreatic d cell developmentGO:000332410.070
neuron apoptotic processGO:0051402200.070
positive regulation of map kinase activityGO:004340630.070
epithelial cell differentiationGO:00308551160.070
regulation of organ growthGO:004662030.069
pancreatic d cell differentiationGO:000331120.068
purine containing compound metabolic processGO:0072521290.068
sequestering of calcium ionGO:005120830.065
pituitary gland developmentGO:0021983160.065
carbohydrate derivative biosynthetic processGO:1901137430.065
positive regulation of apoptotic signaling pathwayGO:200123510.065
regulation of programmed cell deathGO:00430671010.064
anatomical structure homeostasisGO:0060249360.064
forebrain neuron fate commitmentGO:002187710.064
neurological system processGO:0050877620.064
midbrain hindbrain boundary developmentGO:0030917230.063
retinal ganglion cell axon guidanceGO:0031290350.063
nucleotide biosynthetic processGO:0009165210.063
regulation of circadian rhythmGO:004275240.063
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.062
specification of symmetryGO:00097992040.062
cellular localizationGO:0051641970.062
cell proliferationGO:0008283800.061
ion transportGO:00068111140.061
lateral inhibitionGO:004633110.060
Fly
single organism reproductive processGO:0044702400.059
cellular response to stressGO:0033554620.059
intracellular transportGO:0046907320.058
organic acid metabolic processGO:0006082310.058
forebrain generation of neuronsGO:0021872140.057
optomotor responseGO:007163210.057
regulation of cellular protein metabolic processGO:0032268520.056
regulation of cytokine productionGO:000181730.056
anion transportGO:0006820380.056
single organism transportGO:00447652060.056
dopaminergic neuron differentiationGO:0071542140.055
neural tube patterningGO:0021532330.055
single organism behaviorGO:0044708240.054
regulation of cellular ketone metabolic processGO:001056570.054
neuron fate specificationGO:0048665200.054
organic substance transportGO:0071702580.054
ovulation cycle processGO:002260220.053
forebrain neuron developmentGO:002188470.053
dicarboxylic acid transportGO:000683510.053
regulation of neurological system processGO:003164420.052
camp biosynthetic processGO:0006171110.052
inner ear developmentGO:00488391260.052
embryo development ending in birth or egg hatchingGO:00097922710.052
regulation of membrane potentialGO:0042391230.051
regulation of cellular component organizationGO:0051128860.051
monoamine transportGO:001584410.050
negative regulation of biosynthetic processGO:0009890550.050
homeostasis of number of cellsGO:0048872620.050
organic anion transportGO:0015711150.050
oxoacid metabolic processGO:0043436310.050
regulation of chemotaxisGO:0050920180.049
agingGO:000756820.049
regulation of synapse organizationGO:005080730.048
regulation of protein catabolic processGO:004217610.048
purine ribonucleotide metabolic processGO:0009150270.048
gastrulationGO:00073692080.048
ovulation cycleGO:004269820.048
pectoral fin developmentGO:0033339500.046
spinal cord motor neuron differentiationGO:0021522260.046
commissural neuron axon guidanceGO:007167930.046
muscle fiber developmentGO:0048747520.046
smooth muscle tissue developmentGO:004874510.045
g protein coupled receptor signaling pathwayGO:0007186740.045
regulation of neuron apoptotic processGO:0043523170.045
carboxylic acid metabolic processGO:0019752220.044
digestive tract morphogenesisGO:00485462310.044
transmembrane transportGO:00550851200.044
regulation of cell proliferationGO:0042127370.044
central nervous system neuron axonogenesisGO:0021955180.044
cartilage developmentGO:0051216960.044
positive regulation of multicellular organismal processGO:0051240520.044
regulation of phGO:000688530.043
regulation of response to external stimulusGO:0032101310.043
dopamine biosynthetic processGO:004241620.043
regulation of cell developmentGO:00602841000.043
positive regulation of transportGO:005105020.042
camera type eye morphogenesisGO:00485931080.042
cell migrationGO:00164772370.042
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.042
cyclic nucleotide biosynthetic processGO:0009190180.042
cellular pigmentationGO:0033059300.042
cell projection morphogenesisGO:00488582440.042
immune system developmentGO:00025201910.042
negative regulation of cellular biosynthetic processGO:0031327550.042
regulation of sequestering of calcium ionGO:005128240.041
sexual reproductionGO:0019953360.041
regulation of hormone secretionGO:004688320.041
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.041
negative regulation of macromolecule metabolic processGO:0010605760.041
positive regulation of translationGO:004572710.041
cranial nerve developmentGO:0021545420.040
regulation of blood pressureGO:000821710.039
olfactory lobe developmentGO:002198840.039
regulation of synaptic plasticityGO:004816710.039
formation of primary germ layerGO:0001704620.039
divalent inorganic cation transportGO:0072511210.039
proximal distal pattern formationGO:000995410.039
hormone transportGO:000991420.038
cell projection organizationGO:00300302840.038
regulation of cellular amine metabolic processGO:003323800.038
catecholamine biosynthetic processGO:004242320.038
regulation of multicellular organism growthGO:004001440.038
regulation of axon extensionGO:0030516240.038
myeloid cell homeostasisGO:0002262560.038
cell morphogenesisGO:00009022890.038
hormone secretionGO:004687920.037
organelle localizationGO:0051640490.037
response to nicotineGO:003509420.037
nucleoside phosphate biosynthetic processGO:1901293210.037
camp metabolic processGO:0046058110.036
regulation of oligodendrocyte differentiationGO:004871310.036
circadian rhythmGO:0007623190.036
activation of mapk activityGO:000018730.036
regulation of cyclic nucleotide biosynthetic processGO:0030802150.036
response to corticosteroidGO:003196010.036
protein metabolic processGO:00195381830.035
phosphorylationGO:0016310690.035
semicircular canal developmentGO:0060872240.034
circadian sleep wake cycle processGO:002241020.034
regulation of protein metabolic processGO:0051246560.034
purine containing compound biosynthetic processGO:0072522200.034
ectodermal placode developmentGO:0071696370.034
negative regulation of gene expressionGO:0010629650.034
response to amino acidGO:004320020.033
negative regulation of apoptotic processGO:0043066550.033
negative regulation of gliogenesisGO:001401410.033
forebrain regionalizationGO:002187140.033
regulation of bone remodelingGO:004685020.033
regulation of axon guidanceGO:190266780.033
positive regulation of cytoskeleton organizationGO:005149530.033
erk1 and erk2 cascadeGO:007037140.033
developmental growthGO:00485891660.033
dopamine metabolic processGO:004241720.033
regulation of transportGO:0051049450.032
negative regulation of synapse assemblyGO:005196420.031
exocrine pancreas developmentGO:0031017280.031
cell type specific apoptotic processGO:0097285220.031
response to ketoneGO:190165410.031
chemical homeostasisGO:0048878490.031
hormone mediated signaling pathwayGO:000975590.031
digestive tract developmentGO:00485652650.031
spermatid developmentGO:000728620.031
cellular carbohydrate metabolic processGO:004426240.031
cellular response to oxygen levelsGO:007145310.031
peptidyl serine phosphorylationGO:001810510.030
cilium morphogenesisGO:0060271850.030
positive regulation of response to external stimulusGO:003210390.030
positive regulation of molecular functionGO:0044093330.030
regulation of apoptotic processGO:0042981980.030
regulation of purine nucleotide metabolic processGO:1900542170.030
blood circulationGO:0008015870.030
camera type eye developmentGO:00430102220.030
positive regulation of catabolic processGO:000989640.030
thermosensory behaviorGO:004004010.030
pancreas developmentGO:0031016840.030
forebrain cell migrationGO:002188510.030
cell morphogenesis involved in differentiationGO:00009041950.029
positive regulation of stem cell proliferationGO:200064810.029
regulation of response to extracellular stimulusGO:003210410.029
reproductionGO:0000003400.029
cell chemotaxisGO:0060326170.029
purine ribonucleotide biosynthetic processGO:0009152200.029
positive regulation of secretion by cellGO:190353210.029
response to mechanical stimulusGO:0009612240.029
axonal fasciculationGO:0007413110.028
multicellular organismal reproductive processGO:0048609350.028
cellular amino acid metabolic processGO:000652070.028
cellular response to hypoxiaGO:007145610.028
regulation of cyclic nucleotide metabolic processGO:0030799150.028
positive regulation of cytosolic calcium ion concentrationGO:000720440.028
rostrocaudal neural tube patterningGO:0021903290.028
exocrine system developmentGO:0035272280.028
cerebellar cortex developmentGO:002169550.028
type b pancreatic cell developmentGO:000332340.028
positive regulation of phosphorus metabolic processGO:0010562210.027
regulation of cellular component movementGO:0051270550.027
regulation of blood vessel sizeGO:005088020.027
regulation of cell migrationGO:0030334400.027
melanosome localizationGO:0032400210.027
purine nucleotide biosynthetic processGO:0006164200.027
synaptic transmission glycinergicGO:006001210.027
regulation of hormone levelsGO:0010817210.027
sensory organ developmentGO:00074233930.027
amine metabolic processGO:000930820.027
calcium ion importGO:007050940.027
telencephalon developmentGO:0021537140.027
cellular lipid metabolic processGO:0044255360.026
regulation of skeletal muscle tissue developmentGO:004864140.026
negative regulation of cytokine productionGO:000181810.026
regulation of dendrite developmentGO:005077330.026
otolith morphogenesisGO:003247480.026
regulation of stem cell proliferationGO:007209120.026
enzyme linked receptor protein signaling pathwayGO:00071671060.026
terpenoid metabolic processGO:0006721150.026
epithalamus developmentGO:0021538100.026
connective tissue developmentGO:0061448990.026
cellular amine metabolic processGO:004410620.026
negative regulation of locomotionGO:0040013180.026
chemosensory behaviorGO:000763510.025
peripheral nervous system developmentGO:0007422550.025
response to extracellular stimulusGO:0009991100.025
response to dexamethasoneGO:007154810.025
female sex differentiationGO:004666040.025
cellular ketone metabolic processGO:0042180110.025
meiotic nuclear divisionGO:000712640.025
tissue homeostasisGO:0001894250.025
cilium assemblyGO:0042384580.025
regulation of synaptic growth at neuromuscular junctionGO:000858210.025
cellular response to decreased oxygen levelsGO:003629410.025
fin developmentGO:0033333770.025
organic acid catabolic processGO:001605430.025
multi organism processGO:00517041340.024
negative regulation of programmed cell deathGO:0043069580.024
oxidation reduction processGO:0055114410.024
regulation of tube sizeGO:003515020.024
positive regulation of nervous system developmentGO:0051962250.024
regulation of system processGO:0044057400.024
germ line stem cell maintenanceGO:003071820.024
small molecule catabolic processGO:004428230.024
response to glucocorticoidGO:005138410.024
cellular protein metabolic processGO:00442671290.024
lipid metabolic processGO:0006629520.023
cellular response to steroid hormone stimulusGO:0071383310.023
vasculature developmentGO:00019442780.023
positive regulation of phosphate metabolic processGO:0045937210.023
cerebellum developmentGO:0021549170.023
heart processGO:0003015710.023
response to nutrient levelsGO:0031667100.023
eye developmentGO:00016542770.023
neuron projection extension involved in neuron projection guidanceGO:1902284100.023
maintenance of locationGO:005123540.023
neurotransmitter transportGO:000683620.023
metencephalon developmentGO:0022037270.023
positive regulation of cellular protein metabolic processGO:0032270220.023
negative regulation of multicellular organismal processGO:0051241690.023
embryonic organ morphogenesisGO:00485622740.022
ear developmentGO:00435831270.022
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.022
ribonucleotide biosynthetic processGO:0009260200.022
response to osmotic stressGO:0006970110.022
cardiac chamber formationGO:000320740.022
determination of bilateral symmetryGO:00098552040.022
anterior posterior axon guidanceGO:003356450.022
regulation of extrinsic apoptotic signaling pathwayGO:200123630.022
monocarboxylic acid biosynthetic processGO:0072330120.022
autophagyGO:000691440.021
organophosphate metabolic processGO:0019637370.021
regulation of transferase activityGO:0051338160.021
polyol metabolic processGO:001975110.021
optokinetic behaviorGO:000763490.021
larval developmentGO:000216420.021
trigeminal nerve developmentGO:002155930.021
digestive system processGO:002260090.021
regulation of purine nucleotide catabolic processGO:003312120.021

otpa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.379
disease of metabolismDOID:001466700.043
nervous system diseaseDOID:86300.028