Danio rerio

0 known processes

als2b

amyotrophic lateral sclerosis 2b (juvenile)

als2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organelle organizationGO:00069962270.075
organelle assemblyGO:00709251100.070
nucleobase containing compound metabolic processGO:00061392740.069
larval developmentGO:000216420.064
protein localization to nucleusGO:003450430.064
nucleic acid metabolic processGO:00903042440.061
signal transductionGO:00071654550.059
regulation of meiotic cell cycleGO:005144510.056
protein import into nucleusGO:000660630.055
organic cyclic compound metabolic processGO:19013603010.055
cellular response to external stimulusGO:007149620.054
autophagyGO:000691440.054
head developmentGO:00603223030.054
cellular response to nutrient levelsGO:003166920.053
phagocytosisGO:000690930.051
negative regulation of protein kinase activityGO:000646940.051
meiotic nuclear divisionGO:000712640.048
maintenance of locationGO:005123540.047
nucleobase containing compound biosynthetic processGO:00346542050.047
positive regulation of cell cycleGO:004578730.047
regulation of reactive oxygen species metabolic processGO:200037720.046
agingGO:000756820.045
organism emergence from protective structureGO:007168440.044
nuclear transportGO:005116940.044
cellular protein catabolic processGO:004425740.044
vasculature developmentGO:00019442780.043
cellular biosynthetic processGO:00442492860.043
biosynthetic processGO:00090582940.042
regulation of bindingGO:005109830.042
nucleocytoplasmic transportGO:000691340.042
gene expressionGO:00104672520.042
cellular response to extracellular stimulusGO:003166820.041
locomotor rhythmGO:004547530.041
stem cell maintenanceGO:001982740.041
positive regulation of catabolic processGO:000989640.041
single organism localizationGO:19025782250.040
cellular macromolecule metabolic processGO:00442603910.039
regulation of circadian rhythmGO:004275240.039
nitrogen compound metabolic processGO:00068073190.039
guanosine containing compound catabolic processGO:190106920.039
proteolysis involved in cellular protein catabolic processGO:005160330.038
negative regulation of protein phosphorylationGO:000193340.038
positive regulation of transportGO:005105020.038
guanosine containing compound metabolic processGO:190106840.038
regulation of stem cell differentiationGO:200073640.037
response to nutrientGO:000758430.037
single organism organelle organizationGO:19025891990.037
sensory organ developmentGO:00074233930.037
embryonic organ morphogenesisGO:00485622740.036
sensory organ morphogenesisGO:00905962000.036
regulation of biosynthetic processGO:00098892500.036
xenobiotic metabolic processGO:000680540.036
protein polymerizationGO:005125840.035
heterocycle metabolic processGO:00464832900.035
response to monosaccharideGO:003428430.035
positive regulation of cellular component biogenesisGO:004408930.034
macromolecule biosynthetic processGO:00090592270.034
cell surface receptor signaling pathwayGO:00071663250.034
chordate embryonic developmentGO:00430092710.034
cellular aromatic compound metabolic processGO:00067252950.034
cellular nitrogen compound metabolic processGO:00346412900.034
mitochondrion organizationGO:000700540.033
regulation of organ growthGO:004662030.033
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.033
gtp catabolic processGO:000618420.033
primary neural tube formationGO:001402010.033
organic substance biosynthetic processGO:19015762890.033
membrane fusionGO:006102520.033
modification dependent protein catabolic processGO:001994130.032
blood vessel morphogenesisGO:00485142160.032
regulation of cell matrix adhesionGO:000195210.031
cellular pigmentationGO:0033059300.031
meiotic cell cycle processGO:190304630.031
double strand break repairGO:000630230.031
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.031
single organism nuclear importGO:190259330.031
regulation of protein complex assemblyGO:004325430.031
response to carbohydrateGO:000974330.031
positive regulation of cellular catabolic processGO:003133130.031
immune system processGO:00023762410.031
negative regulation of biological processGO:00485193040.031
regulation of cytoplasmic transportGO:190364940.031
regulation of autophagyGO:001050630.031
muscle cell differentiationGO:00426921390.031
cellular response to starvationGO:000926710.031
i kappab kinase nf kappab signalingGO:000724940.031
negative regulation of epithelial cell proliferationGO:005068010.030
determination of left right symmetryGO:00073681790.030
protein targeting to nucleusGO:004474430.030
heart developmentGO:00075073130.030
meiotic chromosome segregationGO:004513230.030
proteasomal protein catabolic processGO:001049820.030
lipid storageGO:001991510.030
regulation of cellular biosynthetic processGO:00313262450.030
blood vessel developmentGO:00015682460.030
morphogenesis of an epitheliumGO:00020093330.029
regulation of protein targetingGO:190353320.029
cellular response to chemical stimulusGO:00708871570.029
regulation of dna replicationGO:000627530.029
regulation of cellular metabolic processGO:00313233200.029
regulation of signal transductionGO:00099662250.029
eye morphogenesisGO:00485921440.029
regulation of multicellular organism growthGO:004001440.029
digestive tract developmentGO:00485652650.029
gtp metabolic processGO:004603940.028
cellular nitrogen compound biosynthetic processGO:00442712180.028
cellular response to oxygen levelsGO:007145310.028
specification of symmetryGO:00097992040.028
single organism metabolic processGO:00447102170.028
neuron neuron synaptic transmissionGO:000727010.028
regulation of protein transportGO:005122330.028
establishment of protein localization to organelleGO:007259440.028
immune system developmentGO:00025201910.028
regulation of cell substrate adhesionGO:001081010.027
negative regulation of cellular processGO:00485232830.027
regulation of establishment of protein localizationGO:007020140.027
tube morphogenesisGO:00352393490.027
regulation of protein catabolic processGO:004217610.027
cilium morphogenesisGO:0060271850.027
hatchingGO:003518840.027
response to stressGO:00069502630.026
amine metabolic processGO:000930820.026
glucose importGO:004632320.026
brain developmentGO:00074202930.026
tube closureGO:006060610.026
cilium assemblyGO:0042384580.026
organic acid metabolic processGO:0006082310.026
multicellular organism growthGO:003526440.026
regulation of nucleobase containing compound metabolic processGO:00192192500.026
cellular component morphogenesisGO:00329893360.026
gastrulationGO:00073692080.026
cell matrix adhesionGO:000716040.025
cytokinesisGO:000091030.025
regulation of protein localization to nucleusGO:190018020.025
cilium organizationGO:0044782710.025
energy reserve metabolic processGO:000611220.025
protein stabilizationGO:005082120.025
macroautophagyGO:001623610.025
regulation of gene expressionGO:00104682650.025
ubiquitin dependent protein catabolic processGO:000651130.025
female gonad developmentGO:000858540.024
transcription dna templatedGO:00063511810.024
regulation of protein ubiquitinationGO:003139630.024
regulation of cellular ketone metabolic processGO:001056570.024
cell substrate adhesionGO:003158940.024
regulation of carbohydrate metabolic processGO:000610940.024
nuclear importGO:005117030.024
cellular component biogenesisGO:00440851780.024
oxoacid metabolic processGO:0043436310.024
negative regulation of kinase activityGO:003367340.024
peptidyl serine phosphorylationGO:001810510.024
multi organism processGO:00517041340.024
cellular macromolecule biosynthetic processGO:00346452240.023
digestive system developmentGO:00551232890.023
regulation of macromolecule metabolic processGO:00602553170.023
carboxylic acid metabolic processGO:0019752220.023
cell morphogenesisGO:00009022890.023
determination of bilateral symmetryGO:00098552040.023
cellular amino acid metabolic processGO:000652070.023
microtubule based movementGO:0007018330.023
regulation of epithelial cell proliferationGO:005067830.023
response to glucoseGO:000974930.023
regulation of primary metabolic processGO:00800903110.023
small molecule catabolic processGO:004428230.023
actin polymerization or depolymerizationGO:000815420.023
regulation of nucleocytoplasmic transportGO:004682220.023
regionalizationGO:00030022740.022
negative regulation of map kinase activityGO:004340720.022
regulation of metabolic processGO:00192223590.022
modification dependent macromolecule catabolic processGO:004363230.022
antimicrobial humoral responseGO:001973020.022
regulation of macromolecule biosynthetic processGO:00105562250.022
response to hexoseGO:000974630.022
regulation of intracellular protein transportGO:003315730.022
cellular component assembly involved in morphogenesisGO:00109271070.022
cellular carbohydrate metabolic processGO:004426240.022
response to chemicalGO:00422213200.022
intra s dna damage checkpointGO:003157310.022
fertilizationGO:000956630.022
lipid catabolic processGO:001604240.022
regulation of cellular component organizationGO:0051128860.021
heterocycle biosynthetic processGO:00181302150.021
regulation of metal ion transportGO:001095940.021
response to external stimulusGO:00096052640.021
positive regulation of gtpase activityGO:004354710.021
negative regulation of tor signalingGO:003200720.021
cellular amine metabolic processGO:004410620.021
dna templated transcription elongationGO:000635430.021
stem cell proliferationGO:007208940.021
nuclear exportGO:005116810.021
embryonic organ developmentGO:00485683810.020
positive regulation of nucleotide catabolic processGO:003081310.020
regulation of protein import into nucleusGO:004230620.020
neurotransmitter secretionGO:000726920.020
striated muscle cell differentiationGO:00511461290.020
embryo development ending in birth or egg hatchingGO:00097922710.020
mitotic dna integrity checkpointGO:004477440.020
synaptic vesicle localizationGO:009747910.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
cellular modified amino acid metabolic processGO:000657530.020
protein acetylationGO:000647320.020
organelle fusionGO:004828430.020
homeostasis of number of cellsGO:0048872620.020
response to drugGO:004249330.020
regulation of nucleoside metabolic processGO:000911820.020
regulation of cell activationGO:005086510.020
peptidyl lysine acetylationGO:001839420.020
single fertilizationGO:000733830.019
positive regulation of cell substrate adhesionGO:001081110.019
rna transportGO:005065820.019
establishment of rna localizationGO:005123630.019
internal protein amino acid acetylationGO:000647520.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
positive regulation of purine nucleotide catabolic processGO:003312310.019
nucleic acid transportGO:005065720.019
response to uvGO:000941130.019
regulation of purine nucleotide catabolic processGO:003312120.019
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.019
regulation of nucleotide catabolic processGO:003081120.019
positive regulation of cytoskeleton organizationGO:005149530.019
spermatid differentiationGO:004851520.019
regulation of reproductive processGO:200024140.019
melanosome transportGO:0032402190.019
chemosensory behaviorGO:000763510.019
striated muscle cell developmentGO:00550021080.019
regulation of nitrogen compound metabolic processGO:00511712510.019
carbohydrate biosynthetic processGO:001605110.019
rna metabolic processGO:00160702190.019
negative regulation of protein localization to nucleusGO:190018120.019
regulation of cellular carbohydrate metabolic processGO:001067540.019
estrogen metabolic processGO:000821020.019
development of primary female sexual characteristicsGO:004654540.019
positive regulation of i kappab kinase nf kappab signalingGO:004312330.019
regulation of muscle contractionGO:000693730.018
positive regulation of nucleoside metabolic processGO:004597910.018
organic cyclic compound biosynthetic processGO:19013622230.018
regulation of blood vessel sizeGO:005088020.018
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.018
positive regulation of biological processGO:00485182530.018
somatic muscle developmentGO:000752540.018
negative regulation of signalingGO:0023057960.018
reactive oxygen species metabolic processGO:007259360.018
response to organic substanceGO:00100331530.018
negative regulation of protein transportGO:005122430.018
startle responseGO:000196440.018
negative regulation of protein serine threonine kinase activityGO:007190120.018
centrosome organizationGO:005129710.018
neurotransmitter transportGO:000683620.018
regulation of cellular amine metabolic processGO:003323800.018
compound eye developmentGO:004874920.018
negative regulation of cytoplasmic transportGO:190365020.018
positive regulation of gtp catabolic processGO:003312610.018
muscle structure developmentGO:00610611960.018
regulation of tube sizeGO:003515020.018
regulation of cell cycleGO:0051726520.018
regulation of transcription dna templatedGO:00063552130.018
golgi vesicle transportGO:004819330.018
digestive tract morphogenesisGO:00485462310.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.017
positive regulation of protein complex assemblyGO:003133420.017
regulation of cell communicationGO:00106462320.017
interspecies interaction between organismsGO:004441940.017
neuroblast proliferationGO:000740520.017
protein localization to plasma membraneGO:007265910.017
regulation of gtp catabolic processGO:003312420.017
transportGO:00068102200.017
nuclear migrationGO:000709730.017
peptide metabolic processGO:000651810.017
cell part morphogenesisGO:00329902460.017
positive regulation of blood circulationGO:190352420.017
protein dephosphorylationGO:000647030.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.017
regulation of dendrite developmentGO:005077330.017
intracellular signal transductionGO:0035556850.017
angiogenesisGO:00015251580.017
rna export from nucleusGO:000640510.017
lateral inhibitionGO:004633110.017
protein metabolic processGO:00195381830.017
positive regulation of cell matrix adhesionGO:000195410.017
spermatid developmentGO:000728620.017
cellular component assemblyGO:00226071700.017
protein importGO:001703830.017
cell cycleGO:0007049930.017
actin filament polymerizationGO:003004120.017
aromatic compound biosynthetic processGO:00194382170.016
regulation of developmental processGO:00507932470.016
internal peptidyl lysine acetylationGO:001839320.016
synaptic vesicle transportGO:004848910.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
phagocytosis engulfmentGO:000691110.016
response to external biotic stimulusGO:0043207970.016
cellular response to stressGO:0033554620.016
eye developmentGO:00016542770.016
mitotic dna damage checkpointGO:004477340.016
regulation of wound healingGO:006104120.016
positive regulation of cell divisionGO:005178120.016
hemopoiesisGO:00300971830.016
regulation of stem cell proliferationGO:007209120.016
regulation of endothelial cell proliferationGO:000193610.016
regulation of cellular amino acid metabolic processGO:000652100.016
small molecule metabolic processGO:0044281770.016
cytoskeleton organizationGO:0007010960.016
response to amineGO:001407510.016
regulation of synapse assemblyGO:005196330.016
positive regulation of cellular processGO:00485222010.016
response to glucocorticoidGO:005138410.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
establishment of synaptic vesicle localizationGO:009748010.016
cell projection morphogenesisGO:00488582440.016
epithelial tube morphogenesisGO:00605621480.016
cellular response to radiationGO:007147840.016
defense responseGO:0006952470.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
response to corticosteroidGO:003196010.016
response to other organismGO:0051707970.016
single organism membrane fusionGO:004480120.015
cellular lipid catabolic processGO:004424230.015
extrinsic apoptotic signaling pathwayGO:009719130.015
regulation of blood coagulationGO:003019310.015
post embryonic organ developmentGO:004856940.015
oxidation reduction processGO:0055114410.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
multicellular organismal signalingGO:0035637220.015
nitric oxide metabolic processGO:004620920.015
myotube differentiationGO:0014902450.015
kidney developmentGO:0001822920.015
carboxylic acid catabolic processGO:004639530.015
response to xenobiotic stimulusGO:0009410450.015
regulation of gtpase activityGO:004308720.015
striated muscle tissue developmentGO:00147061100.015
positive regulation of cell adhesionGO:004578510.015
leukocyte proliferationGO:007066110.015
regulation of signalingGO:00230512350.015
membrane invaginationGO:001032410.015
adherens junction organizationGO:003433240.015
regulation of response to biotic stimulusGO:000283120.015
cellular response to light stimulusGO:007148240.015
regulation of biological qualityGO:00650082630.015
regulation of membrane potentialGO:0042391230.015
regulation of calcium ion transportGO:005192420.015
appendage developmentGO:0048736800.015
growthGO:00400071740.015
protein complex localizationGO:003150310.015
regulation of cytokine productionGO:000181730.015
regulation of myotube differentiationGO:001083020.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
glucose homeostasisGO:004259310.015
regulation of transporter activityGO:003240920.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
cellular response to decreased oxygen levelsGO:003629410.015
cellular localizationGO:0051641970.015
cell motilityGO:00488702440.015
nucleic acid templated transcriptionGO:00976591810.015
embryonic hemopoiesisGO:0035162530.015
somatic stem cell maintenanceGO:003501910.014
negative regulation of protein import into nucleusGO:004230820.014
positive regulation of cytokine productionGO:000181920.014
negative regulation of macromolecule metabolic processGO:0010605760.014
regulation of neural precursor cell proliferationGO:200017730.014
intestinal absorptionGO:005089220.014
cellular ketone metabolic processGO:0042180110.014
peptidyl serine modificationGO:001820920.014
negative regulation of catabolic processGO:000989530.014
tissue remodelingGO:004877140.014
zymogen activationGO:003163830.014
regulation of dna templated transcription in response to stressGO:004362000.014
transcription from rna polymerase ii promoterGO:0006366800.014
urogenital system developmentGO:0001655970.014
microtubule organizing center organizationGO:003102310.014
response to alkaloidGO:004327920.014
response to abiotic stimulusGO:00096281220.014
establishment of pigment granule localizationGO:0051905220.014
regulation of ion transmembrane transporter activityGO:003241220.014
regulation of cellular protein catabolic processGO:190336210.014
embryonic digestive tract developmentGO:004856640.014
sensory perception of chemical stimulusGO:000760630.014
photoreceptor cell developmentGO:0042461400.014
histone h3 k4 methylationGO:005156820.014
epithelial cell differentiationGO:00308551160.014
cellular amide metabolic processGO:004360340.014
cellular response to organic substanceGO:00713101050.014
alpha amino acid metabolic processGO:190160530.014
organic acid catabolic processGO:001605430.014
cell substrate junction assemblyGO:000704420.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
sleepGO:003043110.014
regulation of cell projection assemblyGO:006049140.014
rna localizationGO:000640340.014
cellular component disassemblyGO:002241110.014
regulation of synapse organizationGO:005080730.014
positive regulation of cellular amine metabolic processGO:003324000.014
positive regulation of cell activationGO:005086710.014
exocytosisGO:000688710.014
phosphorylationGO:0016310690.014
regulation of organelle assemblyGO:190211540.014
regulation of skeletal muscle fiber developmentGO:004874220.014
rna biosynthetic processGO:00327741810.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.014
nucleobase containing compound transportGO:001593120.013
regulation of dendrite morphogenesisGO:004881430.013
female meiotic divisionGO:000714320.013
single organism transportGO:00447652060.013
camera type eye developmentGO:00430102220.013
negative regulation of synapse assemblyGO:005196420.013
protein acylationGO:004354330.013
multicellular organismal macromolecule metabolic processGO:004425920.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
spindle assemblyGO:005122520.013
regulation of multicellular organismal processGO:00512392770.013
lymphocyte proliferationGO:004665110.013
catecholamine metabolic processGO:000658420.013
maternal determination of anterior posterior axis embryoGO:000835840.013
regulation of rna metabolic processGO:00512522240.013
positive regulation of secretion by cellGO:190353210.013
negative regulation of intracellular transportGO:003238730.013
muscle tissue developmentGO:00605371100.013
endothelial cell fate commitmentGO:006083930.013
defense response to other organismGO:0098542330.013
cellular response to xenobiotic stimulusGO:0071466350.013
microtubule based processGO:0007017600.013
immune responseGO:0006955280.013
adherens junction assemblyGO:003433310.013
negative regulation of mapk cascadeGO:004340940.013
cellular response to biotic stimulusGO:007121630.013
regulation of rho protein signal transductionGO:003502320.013
regulation of protein polymerizationGO:003227120.013
regulation of response to stimulusGO:00485832690.013
positive regulation of dna metabolic processGO:005105410.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
positive regulation of jak stat cascadeGO:004642720.013
pigment granule localizationGO:0051875250.013
regulation of synaptic plasticityGO:004816710.013
negative regulation of translationGO:001714810.012
negative regulation of dna metabolic processGO:005105340.012
secondary metabolic processGO:001974830.012
circadian rhythmGO:0007623190.012
mononuclear cell proliferationGO:003294310.012
regulation of bmp signaling pathwayGO:0030510390.012
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.012
g1 s transition of mitotic cell cycleGO:000008210.012
phosphate containing compound metabolic processGO:00067961080.012
lateral line system developmentGO:0048925760.012
post golgi vesicle mediated transportGO:000689210.012
carbohydrate homeostasisGO:003350010.012
cell projection organizationGO:00300302840.012
cytoplasm organizationGO:000702840.012
reactive nitrogen species metabolic processGO:200105700.012
mitochondrial transportGO:000683920.012
negative regulation of intracellular protein transportGO:009031730.012
negative regulation of cellular catabolic processGO:003133030.012
collagen metabolic processGO:003296320.012
neuron differentiationGO:00301823530.012
organonitrogen compound metabolic processGO:1901564740.012
cell cycle processGO:0022402530.012
response to biotic stimulusGO:0009607970.012
localization of cellGO:00516742440.012
ventricular cardiac muscle tissue morphogenesisGO:005501020.012
negative regulation of protein complex assemblyGO:003133310.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
actomyosin structure organizationGO:0031032530.012
positive regulation of immune effector processGO:000269930.012
heart morphogenesisGO:00030071560.012
peptide transportGO:001583310.012
ear developmentGO:00435831270.012
regulation of protein bindingGO:004339330.012
regulation of skeletal muscle tissue developmentGO:004864140.012
pronephros developmentGO:0048793690.012
centrosome cycleGO:000709810.012
sensory system developmentGO:0048880760.012
protein secretionGO:000930610.012
regulation of neuronal synaptic plasticityGO:004816810.012
cell substrate adherens junction assemblyGO:000704510.012
alcohol biosynthetic processGO:004616520.012
microtubule polymerization or depolymerizationGO:003110930.012
cellular response to hypoxiaGO:007145610.012
programmed cell deathGO:00125011190.011
developmental growthGO:00485891660.011
locomotionGO:00400113130.011
cellular protein metabolic processGO:00442671290.011
embryonic heart tube morphogenesisGO:00031431080.011
positive regulation of epithelial cell migrationGO:001063420.011
protein modification processGO:00362111000.011
response to amphetamineGO:000197510.011
regulation of response to nutrient levelsGO:003210710.011
positive regulation of epithelial cell differentiationGO:003085820.011
positive regulation of protein polymerizationGO:003227320.011

als2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.023
musculoskeletal system diseaseDOID:1700.015
disease of metabolismDOID:001466700.015
cardiovascular system diseaseDOID:128700.015
immune system diseaseDOID:291400.013
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
inherited metabolic disorderDOID:65500.012