Danio rerio

28 known processes

spna2

spectrin alpha 2

(Aliases: wu:fk32a10,wu:fa20e05,zgc:112229,im:7157190,wu:fb33g08,MGC112229)

spna2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component morphogenesisGO:00329893360.700
Mouse
cell morphogenesis involved in neuron differentiationGO:00486671630.688
organelle organizationGO:00069962270.629
Mouse Rat Worm
cell morphogenesisGO:00009022890.543
Mouse
axonogenesisGO:00074091520.520
microtubule based processGO:0007017600.465
cognitionGO:005089010.418
microtubule based movementGO:0007018330.394
cell morphogenesis involved in differentiationGO:00009041950.298
regulation of peptidyl tyrosine phosphorylationGO:005073010.291
microtubule organizing center organizationGO:003102310.287
axon developmentGO:00615641660.282
centrosome organizationGO:005129710.249
synaptic growth at neuromuscular junctionGO:005112420.244
neuron projection morphogenesisGO:00488121610.243
amine metabolic processGO:000930820.233
cellular component biogenesisGO:00440851780.226
positive regulation of wound healingGO:009030310.222
regulation of cell morphogenesisGO:0022604420.217
Mouse
locomotionGO:00400113130.213
Worm
regulation of axonogenesisGO:0050770320.194
localization of cellGO:00516742440.190
regulation of synapse organizationGO:005080730.190
cell part morphogenesisGO:00329902460.180
establishment of protein localization to organelleGO:007259440.173
brain developmentGO:00074202930.171
ras protein signal transductionGO:000726570.168
taxisGO:00423301090.168
neuron differentiationGO:00301823530.166
digestive system developmentGO:00551232890.164
morphogenesis of an epitheliumGO:00020093330.161
larval developmentGO:000216420.159
Worm
response to stressGO:00069502630.158
regulation of protein bindingGO:004339330.155
Mouse
positive regulation of cell adhesionGO:004578510.153
tube morphogenesisGO:00352393490.152
oxoacid metabolic processGO:0043436310.149
agingGO:000756820.147
head developmentGO:00603223030.145
cellular amine metabolic processGO:004410620.141
cell projection morphogenesisGO:00488582440.140
negative regulation of synapse assemblyGO:005196420.135
regulation of cell shapeGO:000836010.132
Mouse
regulation of synapse assemblyGO:005196330.129
cytoskeleton organizationGO:0007010960.128
Mouse Rat
extrinsic apoptotic signaling pathwayGO:009719130.123
skeletal system developmentGO:00015011810.123
posterior lateral line nerve developmentGO:004891880.120
embryonic organ morphogenesisGO:00485622740.119
neuron projection developmentGO:00311751800.116
positive regulation of biological processGO:00485182530.116
Mouse Worm
regulation of cellular amine metabolic processGO:003323800.114
cellular amino acid metabolic processGO:000652070.113
centrosome cycleGO:000709810.112
cellular component assemblyGO:00226071700.112
maintenance of locationGO:005123540.112
regulation of cellular amino acid metabolic processGO:000652100.111
regulation of biological qualityGO:00650082630.110
Mouse
developmental growthGO:00485891660.109
Worm
signal transductionGO:00071654550.108
intracellular transportGO:0046907320.106
neuron developmentGO:00486662620.105
cellular ketone metabolic processGO:0042180110.104
central nervous system developmentGO:00074173870.102
peptidyl tyrosine modificationGO:001821250.102
neuronal action potentialGO:0019228180.101
regulation of signal transductionGO:00099662250.101
regulation of cellular ketone metabolic processGO:001056570.097
regulation of synaptic growth at neuromuscular junctionGO:000858210.097
adult behaviorGO:003053420.093
regulation of macromolecule metabolic processGO:00602553170.093
cranial nerve developmentGO:0021545420.092
neuron projection guidanceGO:0097485860.092
rna polyadenylationGO:004363120.090
regulation of developmental processGO:00507932470.090
Mouse Worm
adherens junction organizationGO:003433240.087
cellular transition metal ion homeostasisGO:004691630.086
single organism transportGO:00447652060.083
ameboidal type cell migrationGO:00016671430.082
organic acid metabolic processGO:0006082310.082
small molecule metabolic processGO:0044281770.082
neuromuscular processGO:005090570.082
posterior lateral line system developmentGO:0048915460.082
mitotic cell cycleGO:0000278640.081
Worm
regulation of establishment of protein localizationGO:007020140.080
cell migrationGO:00164772370.079
regulation of signalingGO:00230512350.079
cellular macromolecule biosynthetic processGO:00346452240.078
digestive tract developmentGO:00485652650.078
mesenchyme developmentGO:00604851270.076
axon guidanceGO:0007411860.076
nerve developmentGO:0021675450.076
vasculature developmentGO:00019442780.074
carboxylic acid metabolic processGO:0019752220.074
single organism cellular localizationGO:1902580460.071
stem cell developmentGO:0048864820.071
regulation of multicellular organism growthGO:004001440.069
Worm
mechanosensory lateral line system developmentGO:0048881490.069
protein import into nucleusGO:000660630.068
myelinationGO:0042552180.068
skeletal system morphogenesisGO:00487051020.068
myelination of posterior lateral line nerve axonsGO:004893250.068
response to woundingGO:00096111160.067
neuromuscular process controlling balanceGO:005088530.067
single organismal cell cell adhesionGO:0016337290.066
nuclear importGO:005117030.066
positive regulation of cellular amine metabolic processGO:003324000.065
cellular component movementGO:00069283350.065
chemotaxisGO:00069351040.065
mrna polyadenylationGO:000637820.064
protein targeting to nucleusGO:004474430.064
cellular localizationGO:0051641970.064
protein complex assemblyGO:0006461300.063
heart developmentGO:00075073130.062
small gtpase mediated signal transductionGO:000726480.061
macromolecular complex disassemblyGO:003298410.061
protein complex disassemblyGO:004324110.061
hepaticobiliary system developmentGO:0061008980.060
protein metabolic processGO:00195381830.060
intracellular signal transductionGO:0035556850.059
protein polyubiquitinationGO:000020940.058
convergent extensionGO:00600261180.058
cellular component disassemblyGO:002241110.057
spindle assemblyGO:005122520.057
gland developmentGO:00487321430.057
nucleic acid metabolic processGO:00903042440.056
neurological system processGO:0050877620.056
stem cell differentiationGO:00488631170.056
positive regulation of small gtpase mediated signal transductionGO:005105710.055
chemosensory behaviorGO:000763510.055
negative regulation of macromolecule metabolic processGO:0010605760.055
system processGO:00030081850.055
heart morphogenesisGO:00030071560.054
macromolecule modificationGO:00434121110.054
nitrogen compound metabolic processGO:00068073190.053
Mouse
meiotic nuclear divisionGO:000712640.053
positive regulation of cellular catabolic processGO:003133130.052
regulation of response to stimulusGO:00485832690.051
regulation of protein transportGO:005122330.051
liver developmentGO:0001889960.051
cell differentiation in hindbrainGO:002153350.051
larval behaviorGO:003053750.049
cell projection organizationGO:00300302840.049
mesenchymal cell developmentGO:0014031780.049
meiotic cell cycle processGO:190304630.049
protein dephosphorylationGO:000647030.049
neuromuscular junction developmentGO:000752890.049
single organism localizationGO:19025782250.048
cellular protein modification processGO:00064641000.048
neural crest cell differentiationGO:0014033720.048
mitotic cell cycle processGO:1903047480.048
Worm
phosphorus metabolic processGO:00067931090.046
regulation of cell adhesionGO:0030155150.046
chordate embryonic developmentGO:00430092710.046
anterior lateral line nerve glial cell developmentGO:004893930.046
multicellular organismal signalingGO:0035637220.046
er to golgi vesicle mediated transportGO:000688810.046
heterocycle biosynthetic processGO:00181302150.046
Mouse
positive regulation of cellular component biogenesisGO:004408930.045
multicellular organism growthGO:003526440.045
Worm
axon cargo transportGO:000808820.045
developmental growth involved in morphogenesisGO:0060560860.045
meiosis iGO:000712710.045
cell surface receptor signaling pathwayGO:00071663250.044
growthGO:00400071740.044
Worm
negative regulation of apoptotic processGO:0043066550.044
organelle assemblyGO:00709251100.044
cell motilityGO:00488702440.043
regulation of extrinsic apoptotic signaling pathwayGO:200123630.043
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.043
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.043
reproductionGO:0000003400.043
morphogenesis of follicular epitheliumGO:001633310.043
axon ensheathmentGO:0008366180.043
nucleocytoplasmic transportGO:000691340.043
positive regulation of neuron projection developmentGO:001097690.043
digestive tract morphogenesisGO:00485462310.042
regulation of bindingGO:005109830.042
Mouse
single organism organelle organizationGO:19025891990.042
Mouse Rat Worm
forebrain developmentGO:0030900960.042
regulation of protein targetingGO:190353320.042
protein modification processGO:00362111000.042
regionalizationGO:00030022740.042
developmental maturationGO:0021700340.042
transportGO:00068102200.041
protein dealkylationGO:000821420.041
mesenchymal cell differentiationGO:0048762870.041
protein localization to nucleusGO:003450430.041
camera type eye developmentGO:00430102220.041
synapse organizationGO:0050808210.040
behaviorGO:0007610740.040
single organism metabolic processGO:00447102170.040
central nervous system neuron developmentGO:0021954290.039
transmission of nerve impulseGO:0019226190.039
neural crest cell developmentGO:0014032620.039
cellular protein metabolic processGO:00442671290.039
regulation of cell growthGO:0001558290.039
protein importGO:001703830.039
histone lysine demethylationGO:007007620.039
gene expressionGO:00104672520.038
cellular macromolecule metabolic processGO:00442603910.037
positive regulation of catabolic processGO:000989640.037
embryo development ending in birth or egg hatchingGO:00097922710.037
Worm
anterior lateral line nerve glial cell differentiationGO:004891330.037
sensory organ developmentGO:00074233930.036
negative regulation of biological processGO:00485193040.036
meiotic chromosome segregationGO:004513230.036
negative regulation of ras protein signal transductionGO:004658010.035
locomotor rhythmGO:004547530.035
protein complex subunit organizationGO:0071822460.035
positive regulation of neuron deathGO:190121610.035
regulation of developmental growthGO:0048638380.034
Worm
g1 s transition of mitotic cell cycleGO:000008210.034
axis specificationGO:0009798430.034
protein localizationGO:0008104400.034
nuclear transportGO:005116940.033
positive regulation of map kinase activityGO:004340630.033
blood vessel morphogenesisGO:00485142160.033
positive regulation of cell cycleGO:004578730.033
regulation of wound healingGO:006104120.032
regulation of rho protein signal transductionGO:003502320.032
protein polymerizationGO:005125840.032
regulation of cell communicationGO:00106462320.032
trabecula morphogenesisGO:006138320.032
regulation of gene expressionGO:00104682650.032
tissue migrationGO:0090130370.032
modification dependent protein catabolic processGO:001994130.031
somatic muscle developmentGO:000752540.031
rna 3 end processingGO:003112320.031
response to chemicalGO:00422213200.031
action potentialGO:0001508190.031
macromolecular complex subunit organizationGO:0043933740.031
rna biosynthetic processGO:00327741810.031
ensheathment of neuronsGO:0007272180.030
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.030
muscle structure developmentGO:00610611960.030
single organism cell adhesionGO:0098602290.030
cellular aromatic compound metabolic processGO:00067252950.030
Mouse
negative regulation of signal transduction in absence of ligandGO:190109910.030
macromolecule localizationGO:0033036540.029
nuclear divisionGO:0000280230.029
Worm
negative regulation of cellular processGO:00485232830.029
proteolysis involved in cellular protein catabolic processGO:005160330.029
biological adhesionGO:0022610400.029
single organism behaviorGO:0044708240.029
primary neural tube formationGO:001402010.028
anterior lateral line nerve glial cell morphogenesis involved in differentiationGO:004894030.028
establishment of localizationGO:00512342440.028
positive regulation of cellular metabolic processGO:0031325940.028
cellular protein complex disassemblyGO:004362410.028
cellular response to extracellular stimulusGO:003166820.027
positive regulation of ras protein signal transductionGO:004657910.027
regulation of protein ubiquitinationGO:003139630.027
single organism nuclear importGO:190259330.027
regulation of cellular component sizeGO:0032535300.027
neuromuscular synaptic transmissionGO:000727420.027
protein depolymerizationGO:005126110.027
positive regulation of protein kinase b signalingGO:005189710.027
protein phosphorylationGO:0006468470.027
lateral line system developmentGO:0048925760.027
peptidyl tyrosine phosphorylationGO:001810850.026
oocyte constructionGO:000730850.026
microtubule based transportGO:0010970100.026
regulation of apoptotic processGO:0042981980.026
mesoderm morphogenesisGO:0048332510.026
response to external stimulusGO:00096052640.025
urogenital system developmentGO:0001655970.025
establishment of organelle localizationGO:0051656450.025
cellular carbohydrate metabolic processGO:004426240.025
positive regulation of cellular amino acid metabolic processGO:004576400.025
establishment of localization in cellGO:0051649770.025
negative regulation of catabolic processGO:000989530.025
myelination of anterior lateral line nerve axonsGO:004891430.025
negative regulation of nitrogen compound metabolic processGO:0051172590.025
regulation of growthGO:0040008420.025
Worm
cellular response to external stimulusGO:007149620.025
multi organism processGO:00517041340.025
organic substance transportGO:0071702580.025
cell adhesionGO:0007155400.024
phagocytosisGO:000690930.024
startle responseGO:000196440.024
glial cell migrationGO:000834730.024
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.024
mitotic dna damage checkpointGO:004477340.024
negative regulation of protein serine threonine kinase activityGO:007190120.024
central nervous system neuron differentiationGO:0021953740.024
response to topologically incorrect proteinGO:003596620.024
rhythmic processGO:0048511210.024
regulation of protein import into nucleusGO:004230620.023
cellular protein localizationGO:0034613200.023
rho protein signal transductionGO:000726650.023
neural crest cell migrationGO:0001755420.023
negative regulation of cytoplasmic transportGO:190365020.023
regulation of cell substrate adhesionGO:001081010.023
regulation of protein catabolic processGO:004217610.023
exocytosisGO:000688710.023
regulation of mitotic cell cycle phase transitionGO:190199080.023
ubiquitin dependent protein catabolic processGO:000651130.023
viral processGO:001603210.022
phosphate containing compound metabolic processGO:00067961080.022
nuclear migrationGO:000709730.022
collateral sproutingGO:004866890.022
negative regulation of kinase activityGO:003367340.022
cerebellar cortex formationGO:002169750.022
negative regulation of protein kinase activityGO:000646940.022
regulation of receptor activityGO:001046920.022
anatomical structure homeostasisGO:0060249360.022
negative regulation of cell deathGO:0060548600.022
blood vessel developmentGO:00015682460.022
positive regulation of cell communicationGO:0010647560.022
hatchingGO:003518840.022
heterocycle metabolic processGO:00464832900.022
Mouse
regulation of dendrite morphogenesisGO:004881430.021
posterior lateral line nerve glial cell differentiationGO:004893150.021
regulation of transferase activityGO:0051338160.021
cell substrate adhesionGO:003158940.021
signal transduction in absence of ligandGO:003803410.021
macromolecular complex assemblyGO:0065003350.021
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.021
protein acetylationGO:000647320.021
cerebellar cortex developmentGO:002169550.021
cytoskeleton dependent intracellular transportGO:0030705100.021
collateral sprouting in absence of injuryGO:004866940.021
cellular nitrogen compound metabolic processGO:00346412900.021
Mouse
sleepGO:003043110.021
rna metabolic processGO:00160702190.021
negative regulation of map kinase activityGO:004340720.021
epithelium migrationGO:0090132250.020
protein complex biogenesisGO:0070271300.020
lateral line nerve glial cell morphogenesis involved in differentiationGO:004893850.020
photoreceptor cell maintenanceGO:0045494110.020
cellular response to nutrient levelsGO:003166920.020
stem cell proliferationGO:007208940.020
cellular response to stressGO:0033554620.020
regulation of cytoplasmic transportGO:190364940.020
compound eye developmentGO:004874920.020
regulation of cell proliferation involved in heart morphogenesisGO:200013620.020
lateral line nerve glial cell developmentGO:004893760.020
positive regulation of cell divisionGO:005178120.020
gastrulationGO:00073692080.020
striated muscle tissue developmentGO:00147061100.020
female sex differentiationGO:004666040.019
cytoskeleton dependent cytokinesisGO:006164030.019
neuron deathGO:0070997210.019
regulation of protein localization to nucleusGO:190018020.019
developmental cell growthGO:0048588520.019
trabecula formationGO:006034320.019
posterior lateral line nerve glial cell developmentGO:004894150.019
regulation of rna metabolic processGO:00512522240.019
oocyte developmentGO:0048599140.019
regulation of anatomical structure morphogenesisGO:00226031300.019
Mouse
negative regulation of protein phosphorylationGO:000193340.018
determination of left right symmetryGO:00073681790.018
organic cyclic compound metabolic processGO:19013603010.018
Mouse
regulation of protein phosphorylationGO:0001932180.018
regulation of cellular protein catabolic processGO:190336210.018
regulation of organelle assemblyGO:190211540.018
protein targeting to membraneGO:000661210.018
mrna 3 end processingGO:003112420.018
organic cyclic compound biosynthetic processGO:19013622230.018
Mouse
epithelial to mesenchymal transitionGO:0001837210.018
organelle localizationGO:0051640490.018
regulation of response to cytokine stimulusGO:006075930.018
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.018
stem cell maintenanceGO:001982740.018
regulation of erk1 and erk2 cascadeGO:007037240.018
positive regulation of transportGO:005105020.018
positive regulation of signal transductionGO:0009967560.018
positive regulation of nucleobase containing compound metabolic processGO:0045935690.018
organonitrogen compound metabolic processGO:1901564740.018
Mouse
iron ion homeostasisGO:005507240.018
phosphatidylinositol 3 kinase signalingGO:001406520.018
histone demethylationGO:001657720.018
positive regulation of stem cell proliferationGO:200064810.017
regulation of protein depolymerizationGO:190187910.017
regulation of cellular biosynthetic processGO:00313262450.017
generation of neuronsGO:00486993850.017
tube closureGO:006060610.017
epithelial tube morphogenesisGO:00605621480.017
positive regulation of neuron apoptotic processGO:004352510.017
mitotic metaphase plate congressionGO:000708010.017
pyruvate metabolic processGO:000609010.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
nucleobase containing compound biosynthetic processGO:00346542050.017
central nervous system neuron axonogenesisGO:0021955180.017
neuron apoptotic processGO:0051402200.017
convergent extension involved in gastrulationGO:0060027710.017
regulation of melanocyte differentiationGO:004563420.017
phosphatidylinositol mediated signalingGO:004801520.017
cellular response to starvationGO:000926710.017
synapse assemblyGO:000741690.017
glutamate receptor signaling pathwayGO:000721510.017
somitogenesisGO:0001756870.017
spermatid developmentGO:000728620.017
cell deathGO:00082191210.017
regulation of transcription dna templatedGO:00063552130.017
transcription dna templatedGO:00063511810.017
oocyte differentiationGO:0009994140.016
microtubule cytoskeleton organizationGO:0000226330.016
regulation of microtubule cytoskeleton organizationGO:007050730.016
positive regulation of signalingGO:0023056560.016
cell cycle g2 m phase transitionGO:004483940.016
epithelial tube formationGO:0072175190.016
protein demethylationGO:000648220.016
regulation of multicellular organismal processGO:00512392770.016
Worm
epithelial cell migrationGO:0010631250.016
regulation of protein kinase activityGO:0045859150.016
vesicle localizationGO:0051648270.016
embryonic organ developmentGO:00485683810.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
ovulation cycleGO:004269820.016
larval locomotory behaviorGO:000834550.015
neuron remodelingGO:001632210.015
cytokinesisGO:000091030.015
sympathetic nervous system developmentGO:004848530.015
response to abiotic stimulusGO:00096281220.015
regulation of protein complex disassemblyGO:004324410.015
tissue homeostasisGO:0001894250.015
regulation of multicellular organismal developmentGO:20000262230.015
regulation of biosynthetic processGO:00098892500.015
mitotic cytokinesisGO:000028130.015
positive regulation of glucose importGO:004632610.015
regulation of erythrocyte differentiationGO:004564620.015
retina homeostasisGO:0001895120.015
positive regulation of myeloid cell differentiationGO:004563920.015
erk1 and erk2 cascadeGO:007037140.015
negative regulation of intracellular transportGO:003238730.015
oocyte anterior posterior axis specificationGO:000731440.015
regulation of protein complex assemblyGO:004325430.015
negative regulation of metabolic processGO:0009892860.015
rna localizationGO:000640340.014
cerebellar cortex morphogenesisGO:002169650.014
modification of morphology or physiology of other organismGO:003582140.014
regenerationGO:0031099910.014
cell projection assemblyGO:0030031640.014
inositol lipid mediated signalingGO:004801720.014
regulation of dendrite developmentGO:005077330.014
wnt signaling pathwayGO:0016055800.014
embryonic heart tube morphogenesisGO:00031431080.014
phosphorylationGO:0016310690.014
regulation of epithelial cell proliferationGO:005067830.014
axon midline choice point recognitionGO:001619940.014
positive regulation of jak stat cascadeGO:004642720.014
mitotic spindle organizationGO:000705250.014
cell cycleGO:0007049930.014
Worm
lateral line nerve developmentGO:004889290.014
apoptotic processGO:00069151160.014
positive regulation of epithelial cell migrationGO:001063420.014
mesoderm developmentGO:0007498880.014
regulation of circadian rhythmGO:004275240.014
angiogenesisGO:00015251580.014
regulation of nitrogen compound metabolic processGO:00511712510.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
regulation of cellular component organizationGO:0051128860.014
Mouse
negative regulation of mapk cascadeGO:004340940.013
negative regulation of developmental processGO:0051093650.013
regulation of nucleocytoplasmic transportGO:004682220.013
regulation of cell matrix adhesionGO:000195210.013
sensory system developmentGO:0048880760.013
locomotory behaviorGO:0007626340.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
microtubule cytoskeleton organization involved in mitosisGO:190285010.013
regulation of purine nucleotide catabolic processGO:003312120.013
ribosomal small subunit biogenesisGO:004227420.013
reactive oxygen species metabolic processGO:007259360.013
positive regulation of cytoskeleton organizationGO:005149530.013
microtubule polymerization or depolymerizationGO:003110930.013
regulation of kinase activityGO:0043549150.013
positive regulation of cellular processGO:00485222010.013
Mouse
eye developmentGO:00016542770.013
retina development in camera type eyeGO:00600411460.013
mitotic dna integrity checkpointGO:004477440.013
proteasomal protein catabolic processGO:001049820.013
cell matrix adhesionGO:000716040.013
outflow tract morphogenesisGO:000315110.013

spna2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.100
Human
nervous system diseaseDOID:86300.047
Human
tauopathyDOID:68000.041
central nervous system diseaseDOID:33100.041
Human
neurodegenerative diseaseDOID:128900.041
disease of metabolismDOID:001466700.023
organ system cancerDOID:005068600.021
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
gastrointestinal system cancerDOID:311900.017
cardiovascular system diseaseDOID:128700.015
musculoskeletal system diseaseDOID:1700.015
intrinsic cardiomyopathyDOID:006003600.015
muscle tissue diseaseDOID:6600.015
muscular diseaseDOID:008000000.015
heart diseaseDOID:11400.015
myopathyDOID:42300.015
cardiomyopathyDOID:005070000.015
sensory system diseaseDOID:005015500.013