Danio rerio

0 known processes

ctssb.2

cathepsin S, b.2

(Aliases: wu:fj84d06,zgc:112489,zgc:111950)

ctssb.2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune system processGO:00023762410.171
Human
superoxide metabolic processGO:000680120.144
proteolysis involved in cellular protein catabolic processGO:005160330.086
Human Mouse
cellular protein catabolic processGO:004425740.083
Human Mouse
response to chemicalGO:00422213200.083
Human
regulation of cell activationGO:005086510.077
regulation of primary metabolic processGO:00800903110.073
cellular response to chemical stimulusGO:00708871570.066
Human
regulation of response to stimulusGO:00485832690.061
Mouse
cell surface receptor signaling pathwayGO:00071663250.060
collagen metabolic processGO:003296320.059
Human
protein metabolic processGO:00195381830.056
Human Mouse
amine metabolic processGO:000930820.055
response to external stimulusGO:00096052640.054
Zebrafish Mouse
larval developmentGO:000216420.053
adaptive immune responseGO:000225050.052
Human
medulla oblongata developmentGO:002155040.052
regulation of immune system processGO:0002682340.052
multicellular organismal metabolic processGO:004423620.050
Human
response to organic substanceGO:00100331530.045
Human
signal transduction in absence of ligandGO:003803410.045
reactive oxygen species metabolic processGO:007259360.042
positive regulation of catabolic processGO:000989640.042
negative regulation of cellular processGO:00485232830.041
symbiosis encompassing mutualism through parasitismGO:004440340.040
regulation of response to oxidative stressGO:190288220.039
regulation of syncytium formation by plasma membrane fusionGO:006014220.038
embryo development ending in birth or egg hatchingGO:00097922710.038
granulocyte migrationGO:0097530110.037
hydrogen peroxide metabolic processGO:004274320.037
positive regulation of response to stimulusGO:0048584800.036
Mouse
regulation of signal transductionGO:00099662250.036
positive regulation of cellular extravasationGO:000269310.034
regulation of blood vessel sizeGO:005088020.034
regulation of protein catabolic processGO:004217610.034
regulation of cellular amino acid metabolic processGO:000652100.034
small molecule metabolic processGO:0044281770.033
camera type eye developmentGO:00430102220.033
positive regulation of cellular catabolic processGO:003133130.032
nuclear transportGO:005116940.032
single organism metabolic processGO:00447102170.031
Human
i kappab kinase nf kappab signalingGO:000724940.031
regulation of establishment of protein localizationGO:007020140.031
negative regulation of protein phosphorylationGO:000193340.031
multicellular organismal macromolecule metabolic processGO:004425920.029
Human
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.029
deathGO:00162651210.029
biological adhesionGO:0022610400.029
multicellular organism growthGO:003526440.029
homeostasis of number of cells within a tissueGO:004887340.029
regulation of peptidyl tyrosine phosphorylationGO:005073010.028
establishment of protein localization to organelleGO:007259440.027
inflammatory responseGO:000695480.027
Mouse
regenerationGO:0031099910.027
regulation of metabolic processGO:00192223590.027
cellular nitrogen compound metabolic processGO:00346412900.027
phagosome maturationGO:009038210.027
signal transductionGO:00071654550.026
muscle tissue developmentGO:00605371100.025
regulation of multicellular organism growthGO:004001440.025
rna metabolic processGO:00160702190.025
interspecies interaction between organismsGO:004441940.025
regulation of cell motilityGO:2000145460.025
negative regulation of biological processGO:00485193040.025
tissue regenerationGO:0042246740.025
positive regulation of transportGO:005105020.024
protein polymerizationGO:005125840.024
regulation of cellular amine metabolic processGO:003323800.024
sensory organ developmentGO:00074233930.023
innate immune responseGO:0045087130.023
cellular amino acid metabolic processGO:000652070.023
cellular macromolecule metabolic processGO:00442603910.022
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
positive regulation of cellular component biogenesisGO:004408930.021
generation of neuronsGO:00486993850.021
regulation of cytokine productionGO:000181730.021
regulation of signalingGO:00230512350.021
negative regulation of blood vessel endothelial cell migrationGO:004353710.021
modification dependent macromolecule catabolic processGO:004363230.021
nucleic acid transportGO:005065720.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.021
cellular protein metabolic processGO:00442671290.021
Human Mouse
tissue remodelingGO:004877140.020
myeloid leukocyte migrationGO:0097529120.020
oxoacid metabolic processGO:0043436310.020
cellular component movementGO:00069283350.020
regulation of inflammatory responseGO:005072720.020
Mouse
regulation of programmed cell deathGO:00430671010.020
nitrogen compound metabolic processGO:00068073190.020
cellular ketone metabolic processGO:0042180110.020
regulation of production of molecular mediator of immune responseGO:000270010.020
negative regulation of protein kinase activityGO:000646940.019
cellular component assemblyGO:00226071700.019
carbohydrate derivative biosynthetic processGO:1901137430.019
regulation of tube sizeGO:003515020.019
regulation of cellular protein catabolic processGO:190336210.018
regulation of neutrophil migrationGO:190262260.018
response to external biotic stimulusGO:0043207970.018
localization of cellGO:00516742440.018
positive regulation of apoptotic signaling pathwayGO:200123510.018
regulation of cellular component organizationGO:0051128860.018
positive regulation of cellular processGO:00485222010.018
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.017
killing of cells in other organism involved in symbiotic interactionGO:005188310.017
peptidyl lysine acetylationGO:001839420.017
regulation of cellular metabolic processGO:00313233200.017
positive regulation of neutrophil extravasationGO:200039110.017
angiogenesisGO:00015251580.017
response to stressGO:00069502630.017
Mouse
regulation of purine nucleotide catabolic processGO:003312120.017
protein secretionGO:000930610.017
leukocyte mediated cytotoxicityGO:000190910.017
lateral line developmentGO:0048882660.016
dorsal motor nucleus of vagus nerve developmentGO:002174440.016
extrinsic apoptotic signaling pathwayGO:009719130.016
organelle fusionGO:004828430.016
regulation of defense responseGO:0031347140.016
Mouse
brain developmentGO:00074202930.016
regulation of apoptotic processGO:0042981980.016
positive regulation of cell communicationGO:0010647560.016
negative regulation of defense responseGO:003134820.016
response to hormoneGO:0009725480.016
Human
positive regulation of cellular amine metabolic processGO:003324000.016
anatomical structure homeostasisGO:0060249360.016
positive regulation of muscle cell differentiationGO:005114910.016
response to abiotic stimulusGO:00096281220.016
Zebrafish
lymphangiogenesisGO:0001946250.016
cell morphogenesisGO:00009022890.015
negative regulation of response to stimulusGO:00485851040.015
hematopoietic stem cell migrationGO:003570140.015
regulation of locomotionGO:0040012550.015
positive regulation of protein complex assemblyGO:003133420.015
apoptotic processGO:00069151160.015
defense response to fungusGO:005083220.015
regulation of metal ion transportGO:001095940.015
embryonic organ developmentGO:00485683810.015
cellular component biogenesisGO:00440851780.015
regulation of cell shapeGO:000836010.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
killing of cells of other organismGO:003164010.015
cell death in response to oxidative stressGO:003647320.015
response to alkaloidGO:004327920.015
negative regulation of cellular metabolic processGO:0031324770.015
epithelial tube morphogenesisGO:00605621480.015
positive regulation of cytoskeleton organizationGO:005149530.015
head developmentGO:00603223030.015
cytoplasmic pattern recognition receptor signaling pathwayGO:000275310.015
programmed cell deathGO:00125011190.015
organonitrogen compound metabolic processGO:1901564740.015
regulation of protein transportGO:005122330.014
immune effector processGO:0002252230.014
regulation of blood pressureGO:000821710.014
negative regulation of kinase activityGO:003367340.014
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
cell deathGO:00082191210.014
regulation of cell deathGO:00109411030.014
ph reductionGO:004585110.014
purine nucleoside monophosphate catabolic processGO:000912840.014
cell projection morphogenesisGO:00488582440.014
regulation of cellular ketone metabolic processGO:001056570.014
organic acid metabolic processGO:0006082310.014
tube morphogenesisGO:00352393490.014
leukocyte chemotaxisGO:0030595120.014
positive regulation of protein polymerizationGO:003227320.013
vasculature developmentGO:00019442780.013
regulation of macromolecule metabolic processGO:00602553170.013
ubiquitin dependent protein catabolic processGO:000651130.013
positive regulation of cell activationGO:005086710.013
heterocycle metabolic processGO:00464832900.013
positive regulation of nucleotide catabolic processGO:003081310.013
retina morphogenesis in camera type eyeGO:0060042790.013
regulation of gtpase activityGO:004308720.013
regulation of protein complex assemblyGO:004325430.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.013
neutrophil chemotaxisGO:0030593100.013
protein import into nucleusGO:000660630.013
regulation of cytoplasmic transportGO:190364940.013
positive regulation of secretionGO:005104710.013
regulation of anatomical structure sizeGO:0090066330.012
locomotionGO:00400113130.012
protein acetylationGO:000647320.012
positive regulation of nucleoside metabolic processGO:004597910.012
positive regulation of cell killingGO:003134320.012
defense responseGO:0006952470.012
Mouse
chordate embryonic developmentGO:00430092710.012
organic substance biosynthetic processGO:19015762890.012
establishment of rna localizationGO:005123630.012
cell motilityGO:00488702440.012
single organism transportGO:00447652060.012
regulation of developmental processGO:00507932470.012
nuclear importGO:005117030.012
nucleobase containing compound biosynthetic processGO:00346542050.012
proteasomal protein catabolic processGO:001049820.012
smooth muscle contractionGO:000693920.012
biosynthetic processGO:00090582940.012
cell chemotaxisGO:0060326170.012
leukocyte homeostasisGO:000177620.011
regulation of cell communicationGO:00106462320.011
ameboidal type cell migrationGO:00016671430.011
organic substance catabolic processGO:1901575280.011
Human Mouse
positive regulation of immune effector processGO:000269930.011
cell killingGO:000190620.011
proteolysisGO:0006508380.011
Human Mouse
regulation of biological qualityGO:00650082630.011
regulation of nitrogen compound metabolic processGO:00511712510.011
rna transportGO:005065820.011
activation of immune responseGO:000225390.011
regulation of nucleocytoplasmic transportGO:004682220.011
amyloid precursor protein metabolic processGO:004298210.011
cytoskeleton organizationGO:0007010960.011
gene expressionGO:00104672520.011
regulation of proteolysisGO:0030162240.011
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.011
regulation of multicellular organismal processGO:00512392770.011
response to amino acidGO:004320020.011
striated muscle tissue developmentGO:00147061100.011
transcription dna templatedGO:00063511810.011
gtp catabolic processGO:000618420.011
regulation of nucleotide catabolic processGO:003081120.011
regulation of cellular component movementGO:0051270550.011
morphogenesis of an epithelial sheetGO:0002011490.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
phosphorus metabolic processGO:00067931090.011
neural nucleus developmentGO:0048857150.011
positive regulation of glial cell differentiationGO:004568710.011
regulation of response to external stimulusGO:0032101310.011
Mouse
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.010
regulation of mrna splicing via spliceosomeGO:004802430.010
regulation of myotube differentiationGO:001083020.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
cellular component morphogenesisGO:00329893360.010
mechanosensory lateral line system developmentGO:0048881490.010
central nervous system developmentGO:00074173870.010
phosphate containing compound metabolic processGO:00067961080.010
gtp metabolic processGO:004603940.010
positive regulation of secretion by cellGO:190353210.010
single organism nuclear importGO:190259330.010
single organism membrane fusionGO:004480120.010
cellular amine metabolic processGO:004410620.010
internal protein amino acid acetylationGO:000647520.010
cell cycle g1 s phase transitionGO:004484310.010
dna methylation or demethylationGO:004472880.010
oxidation reduction processGO:0055114410.010
regulation of gene expressionGO:00104682650.010

ctssb.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.092
inherited metabolic disorderDOID:65500.074
disease of metabolismDOID:001466700.074
immune system diseaseDOID:291400.059
lysosomal storage diseaseDOID:321100.049
nervous system diseaseDOID:86300.013
lipid storage diseaseDOID:945500.012