IMP: Integrative Multi-species Prediction

Danio rerio

37 known processes

wnt4b

wingless-type MMTV integration site family, member 4b

Ensembl: ENSDARG00000040159
Entrez: 791993
ZFIN: ZDB-GENE-000411-1
UniProtKB: Q9IAU3

Process Predictions
Disease Predictions

wnt4b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
tube morphogenesis	GO:0035239	349	0.762	Zebrafish
digestive system development	GO:0055123	289	0.523	Zebrafish
aromatic compound biosynthetic process	GO:0019438	217	0.451	Zebrafish
epithelial cell proliferation involved in liver morphogenesis	GO:0072575	2	0.406	Zebrafish
heart development	GO:0007507	313	0.374	Zebrafish
heart morphogenesis	GO:0003007	156	0.360	Zebrafish
cellular response to external stimulus	GO:0071496	2	0.335
embryonic heart tube development	GO:0035050	133	0.295	Zebrafish
central nervous system development	GO:0007417	387	0.271	Zebrafish
pancreas development	GO:0031016	84	0.265	Zebrafish
chordate embryonic development	GO:0043009	271	0.260	Zebrafish
generation of neurons	GO:0048699	385	0.251	Zebrafish
response to external stimulus	GO:0009605	264	0.230	Zebrafish
regulation of macromolecule metabolic process	GO:0060255	317	0.222	Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway	GO:0022002	1	0.218	Zebrafish
embryo development ending in birth or egg hatching	GO:0009792	271	0.214	Zebrafish
response to chemical	GO:0042221	320	0.211	Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate	GO:0022001	1	0.207	Zebrafish
heterocycle biosynthetic process	GO:0018130	215	0.206	Zebrafish
determination of bilateral symmetry	GO:0009855	204	0.206	Zebrafish
organic cyclic compound biosynthetic process	GO:1901362	223	0.205	Zebrafish
transport	GO:0006810	220	0.201	Zebrafish
developmental growth involved in morphogenesis	GO:0060560	86	0.199	Zebrafish
muscle structure development	GO:0061061	196	0.196
single organism localization	GO:1902578	225	0.192	Zebrafish
nucleic acid metabolic process	GO:0090304	244	0.192	Zebrafish
ion transport	GO:0006811	114	0.188	Zebrafish
blood vessel development	GO:0001568	246	0.186	Zebrafish
convergent extension	GO:0060026	118	0.184	Zebrafish
heart looping	GO:0001947	94	0.183	Zebrafish
cellular macromolecule metabolic process	GO:0044260	391	0.180	Zebrafish
cell morphogenesis involved in differentiation	GO:0000904	195	0.173	Zebrafish
regulation of axonogenesis	GO:0050770	32	0.171	Zebrafish
cell motility	GO:0048870	244	0.167	Zebrafish
wnt signaling pathway involved in digestive tract morphogenesis	GO:0044333	4	0.167	Zebrafish
localization of cell	GO:0051674	244	0.166	Zebrafish
cell projection organization	GO:0030030	284	0.165	Zebrafish
regulation of rna metabolic process	GO:0051252	224	0.160	Zebrafish
digestive tract development	GO:0048565	265	0.157	Zebrafish
mediolateral intercalation	GO:0060031	3	0.157	Zebrafish
regulation of anterior head development	GO:2000742	2	0.156	Zebrafish
apoptotic process	GO:0006915	116	0.155
regulation of gene expression	GO:0010468	265	0.153	Zebrafish
regulation of wnt signaling pathway involved in digestive tract morphogenesis	GO:2000056	2	0.149	Zebrafish
nitrogen compound metabolic process	GO:0006807	319	0.147	Zebrafish
regulation of nitrogen compound metabolic process	GO:0051171	251	0.143	Zebrafish
regulation of anatomical structure morphogenesis	GO:0022603	130	0.140	Zebrafish
embryonic organ development	GO:0048568	381	0.138	Zebrafish
ear development	GO:0043583	127	0.137	Zebrafish
embryonic heart tube morphogenesis	GO:0003143	108	0.135	Zebrafish
vasculature development	GO:0001944	278	0.135	Zebrafish
digestive tract morphogenesis	GO:0048546	231	0.127	Zebrafish
cellular response to starvation	GO:0009267	1	0.126
meiotic nuclear division	GO:0007126	4	0.126
thrombocyte differentiation	GO:0002574	4	0.124	Zebrafish
neuron projection morphogenesis	GO:0048812	161	0.124	Zebrafish
skeletal system morphogenesis	GO:0048705	102	0.123	Zebrafish
regulation of biological quality	GO:0065008	263	0.123	Zebrafish
cell growth	GO:0016049	57	0.122	Zebrafish
organelle organization	GO:0006996	227	0.120
cell migration	GO:0016477	237	0.115	Zebrafish
somite development	GO:0061053	96	0.111	Zebrafish
positive regulation of cell communication	GO:0010647	56	0.109	Zebrafish
cellular response to nutrient levels	GO:0031669	2	0.102
developmental growth	GO:0048589	166	0.101	Zebrafish
gland development	GO:0048732	143	0.100	Zebrafish
meiotic chromosome segregation	GO:0045132	3	0.099
determination of heart left right asymmetry	GO:0061371	117	0.098	Zebrafish
locomotion	GO:0040011	313	0.098	Zebrafish
nucleic acid templated transcription	GO:0097659	181	0.097	Zebrafish
angiogenesis	GO:0001525	158	0.097	Zebrafish
endocrine pancreas development	GO:0031018	27	0.095	Zebrafish
segmentation	GO:0035282	97	0.093	Zebrafish
developmental cell growth	GO:0048588	52	0.092	Zebrafish
hepatic duct development	GO:0061011	2	0.090	Zebrafish
morphogenesis of an epithelium	GO:0002009	333	0.088	Zebrafish
mesoderm morphogenesis	GO:0048332	51	0.087	Zebrafish
motor neuron axon guidance	GO:0008045	23	0.085
neural tube patterning	GO:0021532	33	0.085	Zebrafish
epithelial tube morphogenesis	GO:0060562	148	0.085	Zebrafish
positive regulation of biological process	GO:0048518	253	0.084	Zebrafish
hepaticobiliary system development	GO:0061008	98	0.084	Zebrafish
organic cyclic compound metabolic process	GO:1901360	301	0.083	Zebrafish
anterior head development	GO:0097065	2	0.083	Zebrafish
cellular component morphogenesis	GO:0032989	336	0.082	Zebrafish
regulation of nucleic acid templated transcription	GO:1903506	213	0.080	Zebrafish
muscle tissue development	GO:0060537	110	0.080
striated muscle cell differentiation	GO:0051146	129	0.080
camera type eye morphogenesis	GO:0048593	108	0.079	Zebrafish
spinal cord anterior posterior patterning	GO:0021512	1	0.079	Zebrafish
single organism organelle organization	GO:1902589	199	0.076
cellular component movement	GO:0006928	335	0.074	Zebrafish
larval development	GO:0002164	2	0.074
biosynthetic process	GO:0009058	294	0.074	Zebrafish
regulation of cell projection organization	GO:0031344	44	0.071	Zebrafish
neural plate anterior posterior regionalization	GO:0021999	8	0.071	Zebrafish
rostrocaudal neural tube patterning	GO:0021903	29	0.071	Zebrafish
establishment of localization	GO:0051234	244	0.070	Zebrafish
determination of left right symmetry	GO:0007368	179	0.070	Zebrafish
macromolecule biosynthetic process	GO:0009059	227	0.068	Zebrafish
regulation of signaling	GO:0023051	235	0.068	Zebrafish
midbrain hindbrain boundary development	GO:0030917	23	0.068	Zebrafish
determination of dorsal ventral asymmetry	GO:0048262	34	0.066	Zebrafish
regeneration	GO:0031099	91	0.065	Zebrafish
alpha amino acid metabolic process	GO:1901605	3	0.064
cellular response to extracellular stimulus	GO:0031668	2	0.064
single organism transport	GO:0044765	206	0.064	Zebrafish
cellular response to endogenous stimulus	GO:0071495	68	0.063	Zebrafish
positive regulation of cellular process	GO:0048522	201	0.062	Zebrafish
regionalization	GO:0003002	274	0.062	Zebrafish
regulation of wnt signaling pathway calcium modulating pathway	GO:0008591	3	0.062	Zebrafish
otic vesicle development	GO:0071599	42	0.062	Zebrafish
cell projection morphogenesis	GO:0048858	244	0.062	Zebrafish
positive regulation of epithelial cell differentiation	GO:0030858	2	0.062
gene expression	GO:0010467	252	0.061	Zebrafish
cerebellum morphogenesis	GO:0021587	10	0.061	Zebrafish
neuron development	GO:0048666	262	0.061	Zebrafish
regulation of cell development	GO:0060284	100	0.060	Zebrafish
neural plate pattern specification	GO:0060896	12	0.060	Zebrafish
membrane hyperpolarization	GO:0060081	1	0.058
meiosis ii	GO:0007135	1	0.056
regulation of programmed cell death	GO:0043067	101	0.056
regulation of cellular biosynthetic process	GO:0031326	245	0.056	Zebrafish
lateral line development	GO:0048882	66	0.055	Zebrafish
regulation of biosynthetic process	GO:0009889	250	0.055	Zebrafish
skeletal muscle organ development	GO:0060538	78	0.055
cation homeostasis	GO:0055080	33	0.054	Zebrafish
cellular aromatic compound metabolic process	GO:0006725	295	0.054	Zebrafish
regulation of circadian rhythm	GO:0042752	4	0.053
muscle organ development	GO:0007517	101	0.051
eye field cell fate commitment involved in camera type eye formation	GO:0060898	3	0.051	Zebrafish
otic placode formation	GO:0043049	23	0.051	Zebrafish
cellular component biogenesis	GO:0044085	178	0.050
nucleobase containing compound metabolic process	GO:0006139	274	0.050	Zebrafish
positive regulation of response to stimulus	GO:0048584	80	0.050	Zebrafish
melanin metabolic process	GO:0006582	2	0.050
lipid storage	GO:0019915	1	0.049
endocrine process	GO:0050886	2	0.049
otic vesicle morphogenesis	GO:0071600	34	0.049	Zebrafish
brain development	GO:0007420	293	0.049	Zebrafish
establishment of endothelial barrier	GO:0061028	3	0.049
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.048	Zebrafish
response to wounding	GO:0009611	116	0.048	Zebrafish
lateral line system development	GO:0048925	76	0.048	Zebrafish
sensory organ development	GO:0007423	393	0.048	Zebrafish
hepatocyte proliferation	GO:0072574	2	0.047	Zebrafish
neuromast development	GO:0048884	46	0.047	Zebrafish
anterior posterior pattern specification	GO:0009952	152	0.047	Zebrafish
chemotaxis	GO:0006935	104	0.047	Zebrafish
cell morphogenesis	GO:0000902	289	0.047	Zebrafish
phagocytosis	GO:0006909	3	0.046
negative regulation of biological process	GO:0048519	304	0.046
regulation of macromolecule biosynthetic process	GO:0010556	225	0.046	Zebrafish
sensory system development	GO:0048880	76	0.046	Zebrafish
regulation of multicellular organismal development	GO:2000026	223	0.046	Zebrafish
somitogenesis	GO:0001756	87	0.046	Zebrafish
axon extension	GO:0048675	45	0.046	Zebrafish
regulation of signal transduction	GO:0009966	225	0.045	Zebrafish
regulation of apoptotic process	GO:0042981	98	0.045
immune system process	GO:0002376	241	0.045	Zebrafish
regulation of cellular component organization	GO:0051128	86	0.044
optic placode formation	GO:0001743	4	0.044	Zebrafish
protein metabolic process	GO:0019538	183	0.044	Zebrafish
gastrulation	GO:0007369	208	0.043	Zebrafish
cellular macromolecule biosynthetic process	GO:0034645	224	0.043	Zebrafish
positive regulation of canonical wnt signaling pathway	GO:0090263	4	0.042	Zebrafish
regulation of rna biosynthetic process	GO:2001141	213	0.042	Zebrafish
mesoderm formation	GO:0001707	43	0.042	Zebrafish
neuron differentiation	GO:0030182	353	0.042	Zebrafish
organelle fission	GO:0048285	23	0.041
head development	GO:0060322	303	0.041	Zebrafish
ectodermal placode morphogenesis	GO:0071697	32	0.041	Zebrafish
neuron projection extension	GO:1990138	45	0.040	Zebrafish
cell part morphogenesis	GO:0032990	246	0.040	Zebrafish
membrane invagination	GO:0010324	1	0.040
cytokinesis	GO:0000910	3	0.040
reflex	GO:0060004	2	0.040
regulation of growth	GO:0040008	42	0.040	Zebrafish
fin regeneration	GO:0031101	51	0.040	Zebrafish
cell surface receptor signaling pathway	GO:0007166	325	0.039	Zebrafish
mesenchyme development	GO:0060485	127	0.038
cell adhesion	GO:0007155	40	0.037	Zebrafish
response to stress	GO:0006950	263	0.037	Zebrafish
organic substance biosynthetic process	GO:1901576	289	0.037	Zebrafish
cellular modified amino acid metabolic process	GO:0006575	3	0.036
membrane repolarization	GO:0086009	2	0.036
immune system development	GO:0002520	191	0.036	Zebrafish
specification of symmetry	GO:0009799	204	0.036	Zebrafish
spinal cord patterning	GO:0021511	6	0.036	Zebrafish
positive regulation of cell cycle	GO:0045787	3	0.036
positive regulation of metabolic process	GO:0009893	108	0.036	Zebrafish
neuron projection development	GO:0031175	180	0.035	Zebrafish
neuron projection guidance	GO:0097485	86	0.035	Zebrafish
regulation of reproductive process	GO:2000241	4	0.035
regulation of cytokine production	GO:0001817	3	0.035
thalamus development	GO:0021794	6	0.035	Zebrafish
spindle assembly	GO:0051225	2	0.035
response to carbohydrate	GO:0009743	3	0.034
striated muscle tissue development	GO:0014706	110	0.034
transmembrane transport	GO:0055085	120	0.034
cell fate commitment involved in formation of primary germ layer	GO:0060795	26	0.034	Zebrafish
cellular biosynthetic process	GO:0044249	286	0.034	Zebrafish
negative regulation of response to stimulus	GO:0048585	104	0.034	Zebrafish
pectoral fin development	GO:0033339	50	0.034	Zebrafish
regulation of extent of cell growth	GO:0061387	29	0.034	Zebrafish
convergent extension involved in organogenesis	GO:0060029	10	0.034
gall bladder development	GO:0061010	1	0.033	Zebrafish
response to hormone	GO:0009725	48	0.032
positive regulation of neuron apoptotic process	GO:0043525	1	0.032
axon guidance	GO:0007411	86	0.032	Zebrafish
hindbrain morphogenesis	GO:0021575	22	0.032	Zebrafish
membrane fusion	GO:0061025	2	0.032
microtubule based process	GO:0007017	60	0.032	Zebrafish
regulation of axon extension	GO:0030516	24	0.032	Zebrafish
regulation of neurogenesis	GO:0050767	87	0.031	Zebrafish
phosphorus metabolic process	GO:0006793	109	0.031	Zebrafish
mesoderm development	GO:0007498	88	0.031	Zebrafish
guanosine containing compound metabolic process	GO:1901068	4	0.031
positive regulation of striated muscle tissue development	GO:0045844	1	0.031
nephron development	GO:0072006	31	0.031
cell cycle	GO:0007049	93	0.031
hormone biosynthetic process	GO:0042446	3	0.031
striated muscle cell development	GO:0055002	108	0.031
embryonic skeletal system morphogenesis	GO:0048704	93	0.031	Zebrafish
transcription dna templated	GO:0006351	181	0.030	Zebrafish
system process	GO:0003008	185	0.030
aging	GO:0007568	2	0.030
tissue regeneration	GO:0042246	74	0.030	Zebrafish
phagocytosis engulfment	GO:0006911	1	0.030
meiotic cell cycle process	GO:1903046	3	0.030
endocardial cushion formation	GO:0003272	2	0.030
cellular nitrogen compound metabolic process	GO:0034641	290	0.029	Zebrafish
positive regulation of catabolic process	GO:0009896	4	0.029
cortical cytoskeleton organization	GO:0030865	1	0.029
hematopoietic or lymphoid organ development	GO:0048534	191	0.029	Zebrafish
specification of axis polarity	GO:0065001	4	0.029
negative regulation of jnk cascade	GO:0046329	1	0.028
spinal cord development	GO:0021510	46	0.028	Zebrafish
cellular component assembly	GO:0022607	170	0.028
blood vessel morphogenesis	GO:0048514	216	0.028	Zebrafish
axial mesoderm formation	GO:0048320	4	0.028
regulation of cellular response to growth factor stimulus	GO:0090287	35	0.028	Zebrafish
regulation of jak stat cascade	GO:0046425	3	0.028
behavior	GO:0007610	74	0.028	Zebrafish
secondary metabolic process	GO:0019748	3	0.027
taurine metabolic process	GO:0019530	1	0.027
cellular amino acid metabolic process	GO:0006520	7	0.027
regulation of cardiac muscle tissue development	GO:0055024	1	0.027
ion transmembrane transport	GO:0034220	91	0.027
establishment or maintenance of cell polarity	GO:0007163	29	0.027	Zebrafish
regulation of multicellular organism growth	GO:0040014	4	0.027
regulation of protein complex assembly	GO:0043254	3	0.027
positive regulation of cellular component biogenesis	GO:0044089	3	0.026
positive regulation of striated muscle cell differentiation	GO:0051155	1	0.026
female sex differentiation	GO:0046660	4	0.026
gtp catabolic process	GO:0006184	2	0.026
regulation of cell morphogenesis	GO:0022604	42	0.026	Zebrafish
response to alkaloid	GO:0043279	2	0.026
muscle cell development	GO:0055001	115	0.026
signal transduction	GO:0007165	455	0.025	Zebrafish
macromolecular complex subunit organization	GO:0043933	74	0.025
female meiotic division	GO:0007143	2	0.025
morphogenesis of embryonic epithelium	GO:0016331	30	0.025	Zebrafish
response to other organism	GO:0051707	97	0.025
muscle cell differentiation	GO:0042692	139	0.025
embryonic neurocranium morphogenesis	GO:0048702	15	0.025	Zebrafish
positive regulation of cellular metabolic process	GO:0031325	94	0.024	Zebrafish
response to endogenous stimulus	GO:0009719	83	0.024	Zebrafish
regulation of response to stimulus	GO:0048583	269	0.024	Zebrafish
regulation of metabolic process	GO:0019222	359	0.024	Zebrafish
stem cell proliferation	GO:0072089	4	0.024
epidermal cell fate specification	GO:0009957	4	0.024
homeostatic process	GO:0042592	142	0.024	Zebrafish
stem cell maintenance	GO:0019827	4	0.024
forebrain development	GO:0030900	96	0.023	Zebrafish
formation of primary germ layer	GO:0001704	62	0.023	Zebrafish
regulation of postsynaptic membrane potential	GO:0060078	1	0.023
otic vesicle formation	GO:0030916	27	0.023	Zebrafish
primary neural tube formation	GO:0014020	1	0.023
tissue remodeling	GO:0048771	4	0.023
heterocycle metabolic process	GO:0046483	290	0.023	Zebrafish
neurological system process	GO:0050877	62	0.023
regulation of cell shape	GO:0008360	1	0.023
central nervous system neuron differentiation	GO:0021953	74	0.022	Zebrafish
nuclear division	GO:0000280	23	0.022
hormone secretion	GO:0046879	2	0.022
peptidyl serine phosphorylation	GO:0018105	1	0.022
morphogenesis of a branching structure	GO:0001763	21	0.022
regulation of meiotic cell cycle	GO:0051445	1	0.022
negative regulation of nuclear division	GO:0051784	3	0.022
multicellular organism growth	GO:0035264	4	0.022
cytoskeleton dependent cytokinesis	GO:0061640	3	0.022
skeletal muscle tissue development	GO:0007519	67	0.022
cell fate commitment	GO:0045165	99	0.022	Zebrafish
cortical actin cytoskeleton organization	GO:0030866	1	0.021
gtp metabolic process	GO:0046039	4	0.021
primitive hemopoiesis	GO:0060215	27	0.021
positive regulation of muscle organ development	GO:0048636	1	0.021
determination of dorsal identity	GO:0048263	13	0.021	Zebrafish
regulation of rho protein signal transduction	GO:0035023	2	0.021
programmed cell death	GO:0012501	119	0.021
oxoacid metabolic process	GO:0043436	31	0.021
appendage development	GO:0048736	80	0.021	Zebrafish
nucleoside monophosphate catabolic process	GO:0009125	4	0.021
renal system development	GO:0072001	94	0.021
negative regulation of cell fate commitment	GO:0010454	13	0.021	Zebrafish
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	22	0.021
regulation of dendrite development	GO:0050773	3	0.021
nuclear import	GO:0051170	3	0.021
hormone metabolic process	GO:0042445	19	0.021
embryonic skeletal joint development	GO:0072498	3	0.020
i kappab kinase nf kappab signaling	GO:0007249	4	0.020
synaptic transmission cholinergic	GO:0007271	4	0.020
response to radiation	GO:0009314	51	0.020
negative regulation of mapk cascade	GO:0043409	4	0.020
peptide transport	GO:0015833	1	0.020
hormone transport	GO:0009914	2	0.020
response to uv	GO:0009411	3	0.020
nephron morphogenesis	GO:0072028	2	0.020
positive regulation of multicellular organismal process	GO:0051240	52	0.020
regulation of neuron projection development	GO:0010975	40	0.020	Zebrafish
cilium or flagellum dependent cell motility	GO:0001539	4	0.020
liver development	GO:0001889	96	0.020	Zebrafish
multicellular organismal reproductive process	GO:0048609	35	0.020
response to lipid	GO:0033993	60	0.020
protein import	GO:0017038	3	0.020
embryonic skeletal system development	GO:0048706	97	0.019	Zebrafish
regulation of cell projection assembly	GO:0060491	4	0.019
unidimensional cell growth	GO:0009826	5	0.019	Zebrafish
phosphate containing compound metabolic process	GO:0006796	108	0.019	Zebrafish
spemann organizer formation	GO:0060061	10	0.019	Zebrafish
meiosis i	GO:0007127	1	0.019
cytoskeleton organization	GO:0007010	96	0.019	Zebrafish
negative regulation of epithelial cell proliferation	GO:0050680	1	0.019
oocyte maturation	GO:0001556	4	0.019
epithelial cell differentiation	GO:0030855	116	0.019
positive regulation of rna metabolic process	GO:0051254	59	0.019	Zebrafish
metencephalon development	GO:0022037	27	0.019	Zebrafish
positive regulation of cellular catabolic process	GO:0031331	3	0.019
response to temperature stimulus	GO:0009266	15	0.019
regulation of skeletal muscle tissue development	GO:0048641	4	0.019
synaptic growth at neuromuscular junction	GO:0051124	2	0.019
regulation of response to extracellular stimulus	GO:0032104	1	0.018
single organism cellular localization	GO:1902580	46	0.018	Zebrafish
regulation of epithelial cell proliferation	GO:0050678	3	0.018
convergent extension involved in gastrulation	GO:0060027	71	0.018	Zebrafish
response to metal ion	GO:0010038	34	0.018
dicarboxylic acid metabolic process	GO:0043648	1	0.018
alternative mrna splicing via spliceosome	GO:0000380	1	0.018
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.018	Zebrafish
nephron tubule morphogenesis	GO:0072078	1	0.018
kupffer s vesicle development	GO:0070121	50	0.018	Zebrafish
urogenital system development	GO:0001655	97	0.018
negative regulation of mesodermal cell fate specification	GO:0042662	3	0.018
endocrine system development	GO:0035270	65	0.018	Zebrafish
regulation of cell size	GO:0008361	29	0.018	Zebrafish
regulation of multicellular organismal process	GO:0051239	277	0.018	Zebrafish
protein modification process	GO:0036211	100	0.018	Zebrafish
receptor internalization	GO:0031623	2	0.018
positive regulation of cytoskeleton organization	GO:0051495	3	0.018
appendage morphogenesis	GO:0035107	56	0.018	Zebrafish
regulation of binding	GO:0051098	3	0.018
negative regulation of cell division	GO:0051782	4	0.018
forebrain regionalization	GO:0021871	4	0.018
endocardial cushion morphogenesis	GO:0003203	3	0.018
establishment of mitotic spindle localization	GO:0040001	12	0.018	Zebrafish
regulation of inhibitory postsynaptic membrane potential	GO:0060080	1	0.018
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.017	Zebrafish
myotube differentiation	GO:0014902	45	0.017
estrogen metabolic process	GO:0008210	2	0.017
growth	GO:0040007	174	0.017	Zebrafish
dorsal ventral pattern formation	GO:0009953	125	0.017	Zebrafish
negative regulation of synapse assembly	GO:0051964	2	0.017
regulation of cellular component size	GO:0032535	30	0.017	Zebrafish
cellular response to chemical stimulus	GO:0070887	157	0.017	Zebrafish
microtubule bundle formation	GO:0001578	9	0.017
regulation of receptor activity	GO:0010469	2	0.017
mitotic nuclear division	GO:0007067	18	0.017
positive regulation of apoptotic process	GO:0043065	29	0.017
regulation of hormone levels	GO:0010817	21	0.017
fourth ventricle development	GO:0021592	8	0.017	Zebrafish
liver morphogenesis	GO:0072576	8	0.017	Zebrafish
response to drug	GO:0042493	3	0.017
modification dependent macromolecule catabolic process	GO:0043632	3	0.017
protein polyubiquitination	GO:0000209	4	0.017
neural plate development	GO:0001840	10	0.017	Zebrafish
cell differentiation in hindbrain	GO:0021533	5	0.017
single organism membrane fusion	GO:0044801	2	0.017
nucleobase containing compound biosynthetic process	GO:0034654	205	0.017	Zebrafish
nucleocytoplasmic transport	GO:0006913	4	0.016
embryonic organ morphogenesis	GO:0048562	274	0.016	Zebrafish
eye morphogenesis	GO:0048592	144	0.016	Zebrafish
oogenesis	GO:0048477	14	0.016
cellular protein complex assembly	GO:0043623	19	0.016
negative regulation of secretion	GO:0051048	2	0.016
myeloid cell development	GO:0061515	32	0.016
negative regulation of apoptotic process	GO:0043066	55	0.016
positive regulation of apoptotic signaling pathway	GO:2001235	1	0.016
regulation of cellular amino acid metabolic process	GO:0006521	0	0.016
negative regulation of nervous system development	GO:0051961	22	0.016	Zebrafish
specification of organ axis polarity	GO:0010084	2	0.016
macromolecule modification	GO:0043412	111	0.016	Zebrafish
neural plate regionalization	GO:0060897	10	0.016	Zebrafish
mesodermal cell fate specification	GO:0007501	12	0.016
regulation of wnt signaling pathway involved in dorsal ventral axis specification	GO:2000053	5	0.016	Zebrafish
maintenance of location	GO:0051235	4	0.016	Zebrafish
hemopoiesis	GO:0030097	183	0.016	Zebrafish
cellular protein modification process	GO:0006464	100	0.016	Zebrafish
negative regulation of mitosis	GO:0045839	3	0.016
neural tube development	GO:0021915	62	0.016	Zebrafish
regulation of protein binding	GO:0043393	3	0.016
positive regulation of muscle tissue development	GO:1901863	1	0.016
growth plate cartilage development	GO:0003417	2	0.016
taxis	GO:0042330	109	0.016	Zebrafish
ectoderm development	GO:0007398	9	0.016	Zebrafish
multi organism process	GO:0051704	134	0.016
protein complex subunit organization	GO:0071822	46	0.016
regulation of intracellular signal transduction	GO:1902531	57	0.016
sensory organ morphogenesis	GO:0090596	200	0.016	Zebrafish
macroautophagy	GO:0016236	1	0.016
epithelial cell development	GO:0002064	42	0.015
guanosine containing compound catabolic process	GO:1901069	2	0.015
establishment of cell polarity	GO:0030010	18	0.015	Zebrafish
ectoderm formation	GO:0001705	2	0.015
positive regulation of signal transduction	GO:0009967	56	0.015	Zebrafish
negative regulation of protein phosphorylation	GO:0001933	4	0.015
positive regulation of cell division	GO:0051781	2	0.015
cell projection assembly	GO:0030031	64	0.015
ventricular system development	GO:0021591	12	0.015	Zebrafish
regulation of i kappab kinase nf kappab signaling	GO:0043122	4	0.015
ectodermal placode development	GO:0071696	37	0.015	Zebrafish
myeloid cell homeostasis	GO:0002262	56	0.015
axonogenesis	GO:0007409	152	0.015	Zebrafish
cell substrate adhesion	GO:0031589	4	0.015
bmp signaling pathway	GO:0030509	52	0.015
regulation of glial cell differentiation	GO:0045685	4	0.015
antimicrobial humoral response	GO:0019730	2	0.015
cell fate specification involved in pattern specification	GO:0060573	3	0.015
regulation of developmental process	GO:0050793	247	0.014	Zebrafish
regulation of cellular amine metabolic process	GO:0033238	0	0.014
response to monosaccharide	GO:0034284	3	0.014
regulation of intracellular protein transport	GO:0033157	3	0.014
aorta development	GO:0035904	4	0.014
response to extracellular stimulus	GO:0009991	10	0.014
histone h3 k4 methylation	GO:0051568	2	0.014
spindle assembly involved in meiosis	GO:0090306	1	0.014
endocrine hormone secretion	GO:0060986	2	0.014
zymogen activation	GO:0031638	3	0.014
thyroid gland development	GO:0030878	12	0.014
response to nutrient levels	GO:0031667	10	0.014
positive regulation of neuron death	GO:1901216	1	0.014
floor plate development	GO:0033504	15	0.014
response to light stimulus	GO:0009416	46	0.014
macromolecular complex assembly	GO:0065003	35	0.014
cellular localization	GO:0051641	97	0.014	Zebrafish
mesodermal cell fate commitment	GO:0001710	14	0.014	Zebrafish
circulatory system process	GO:0003013	87	0.014
meiotic spindle organization	GO:0000212	1	0.014
peptidyl threonine modification	GO:0018210	1	0.014
sulfur compound metabolic process	GO:0006790	13	0.014
negative regulation of stem cell differentiation	GO:2000737	2	0.014
cell cell signaling	GO:0007267	52	0.014	Zebrafish
autophagy	GO:0006914	4	0.014
cerebellar cortex development	GO:0021695	5	0.014
synaptic transmission glycinergic	GO:0060012	1	0.014
regulation of hormone secretion	GO:0046883	2	0.014
chromosome organization involved in meiosis	GO:0070192	1	0.014
membrane organization	GO:0061024	21	0.014
regulation of blood pressure	GO:0008217	1	0.014
cell migration involved in gastrulation	GO:0042074	79	0.014	Zebrafish
cellular response to biotic stimulus	GO:0071216	3	0.014
protein phosphorylation	GO:0006468	47	0.014	Zebrafish
ion homeostasis	GO:0050801	41	0.014	Zebrafish
establishment of protein localization to organelle	GO:0072594	4	0.014
ribonucleoside monophosphate catabolic process	GO:0009158	4	0.014
amine metabolic process	GO:0009308	2	0.014
endocardium morphogenesis	GO:0003160	4	0.014
positive regulation of cellular amine metabolic process	GO:0033240	0	0.014
protein polymerization	GO:0051258	4	0.014
positive regulation of signaling	GO:0023056	56	0.014	Zebrafish
stem cell division	GO:0017145	1	0.013
hindbrain formation	GO:0021576	3	0.013
cellular component assembly involved in morphogenesis	GO:0010927	107	0.013
mitotic cell cycle	GO:0000278	64	0.013
cellular response to stress	GO:0033554	62	0.013
protein complex biogenesis	GO:0070271	30	0.013
odontogenesis of dentin containing tooth	GO:0042475	1	0.013
cellular amide metabolic process	GO:0043603	4	0.013
neural plate morphogenesis	GO:0001839	7	0.013	Zebrafish
g1 s transition of mitotic cell cycle	GO:0000082	1	0.013
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	2	0.013
sensory perception of mechanical stimulus	GO:0050954	16	0.013

wnt4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.030
inherited metabolic disorder	DOID:655	0.017
disease of metabolism	DOID:0014667	0.017
nervous system disease	DOID:863	0.016

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