Danio rerio

18 known processes

nphs2

nephrosis 2, idiopathic, steroid-resistant (podocin)

(Aliases: si:dkey-171o17.6,nphs2l)

nphs2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pronephric nephron developmentGO:0039019140.487
regulation of multicellular organismal processGO:00512392770.464
kidney developmentGO:0001822920.420
renal system developmentGO:0072001940.350
cell morphogenesis involved in differentiationGO:00009041950.349
pronephros developmentGO:0048793690.334
renal filtrationGO:0097205100.331
positive regulation of protein complex assemblyGO:003133420.319
chordate embryonic developmentGO:00430092710.310
regulation of multicellular organismal developmentGO:20000262230.295
protein polymerizationGO:005125840.285
nephron tubule morphogenesisGO:007207810.281
neuron differentiationGO:00301823530.278
myotube cell developmentGO:0014904350.270
neuron projection morphogenesisGO:00488121610.267
glomerular basement membrane developmentGO:003283650.265
nephron developmentGO:0072006310.255
establishment of localizationGO:00512342440.254
generation of neuronsGO:00486993850.249
regulation of protein polymerizationGO:003227120.249
regulation of developmental processGO:00507932470.246
skeletal system developmentGO:00015011810.242
cell morphogenesisGO:00009022890.240
regulation of protein complex assemblyGO:004325430.237
negative regulation of biological processGO:00485193040.237
actin polymerization or depolymerizationGO:000815420.226
cell projection morphogenesisGO:00488582440.220
neuron developmentGO:00486662620.207
nephric duct developmentGO:0072176130.207
regulation of anatomical structure morphogenesisGO:00226031300.206
cellular component movementGO:00069283350.200
pronephric glomerulus developmentGO:0039021130.190
larval developmentGO:000216420.182
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.174
nephron epithelium morphogenesisGO:007208810.173
system processGO:00030081850.173
connective tissue developmentGO:0061448990.171
tube morphogenesisGO:00352393490.167
nephron epithelium developmentGO:0072009160.165
regulation of cytoskeleton organizationGO:0051493110.164
regulation of biological qualityGO:00650082630.163
sensory organ developmentGO:00074233930.162
regulation of cytokine productionGO:000181730.160
agingGO:000756820.156
muscle fiber developmentGO:0048747520.156
synaptic target recognitionGO:000803910.153
regulation of metabolic processGO:00192223590.151
locomotionGO:00400113130.146
cell projection organizationGO:00300302840.145
single organism transportGO:00447652060.142
urogenital system developmentGO:0001655970.141
adherens junction organizationGO:003433240.141
cellular pigmentationGO:0033059300.136
renal tubule morphogenesisGO:006133310.134
cilium morphogenesisGO:0060271850.133
cell substrate adhesionGO:003158940.133
response to stressGO:00069502630.131
localization of cellGO:00516742440.118
regulation of cell developmentGO:00602841000.116
determination of bilateral symmetryGO:00098552040.115
cell differentiation involved in kidney developmentGO:0061005130.115
skeletal muscle organ developmentGO:0060538780.113
regulation of anatomical structure sizeGO:0090066330.113
post embryonic organ developmentGO:004856940.112
nephron morphogenesisGO:007202820.112
heart developmentGO:00075073130.111
cell part morphogenesisGO:00329902460.111
branching morphogenesis of an epithelial tubeGO:0048754150.108
morphogenesis of an epitheliumGO:00020093330.108
blood vessel morphogenesisGO:00485142160.108
cell motilityGO:00488702440.107
synaptic transmission cholinergicGO:000727140.106
regulation of cell migration involved in sprouting angiogenesisGO:009004930.106
epithelial tube morphogenesisGO:00605621480.105
positive regulation of protein polymerizationGO:003227320.105
positive regulation of notch signaling pathwayGO:004574730.104
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.104
response to organic substanceGO:00100331530.102
growth plate cartilage morphogenesisGO:000342210.101
adherens junction assemblyGO:003433310.098
ameboidal type cell migrationGO:00016671430.097
striated muscle cell developmentGO:00550021080.096
positive regulation of cytoskeleton organizationGO:005149530.096
regulation of peptidase activityGO:0052547230.096
response to chemicalGO:00422213200.093
single organism metabolic processGO:00447102170.091
regulation of cellular component sizeGO:0032535300.091
cellular nitrogen compound metabolic processGO:00346412900.090
extracellular structure organizationGO:0043062270.090
single organism localizationGO:19025782250.088
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.088
central nervous system developmentGO:00074173870.086
glomerulus developmentGO:0032835270.086
cellular component biogenesisGO:00440851780.085
negative regulation of cellular processGO:00485232830.084
cellular macromolecule metabolic processGO:00442603910.084
regulation of primary metabolic processGO:00800903110.084
regulation of reproductive processGO:200024140.083
eye developmentGO:00016542770.082
developmental growthGO:00485891660.080
positive regulation of epithelial cell differentiationGO:003085820.079
biosynthetic processGO:00090582940.079
regulation of macromolecule metabolic processGO:00602553170.078
kidney epithelium developmentGO:0072073230.077
pronephric duct developmentGO:0039022130.075
renal system processGO:0003014140.073
reproductionGO:0000003400.073
endocrine processGO:005088620.072
muscle cell differentiationGO:00426921390.071
cytoskeleton organizationGO:0007010960.071
regulation of extent of cell growthGO:0061387290.070
intracellular signal transductionGO:0035556850.070
cell surface receptor signaling pathwayGO:00071663250.069
cell morphogenesis involved in neuron differentiationGO:00486671630.069
response to external biotic stimulusGO:0043207970.069
regulation of epithelial cell proliferationGO:005067830.067
cellular biosynthetic processGO:00442492860.066
vasculature developmentGO:00019442780.066
response to external stimulusGO:00096052640.065
embryonic organ developmentGO:00485683810.064
peptidyl serine phosphorylationGO:001810510.064
regulation of organelle organizationGO:0033043290.064
angiogenesisGO:00015251580.064
epithelial cell differentiation involved in kidney developmentGO:0035850130.063
sensory system developmentGO:0048880760.063
actin filament polymerizationGO:003004120.063
protein metabolic processGO:00195381830.062
convergent extension involved in organogenesisGO:0060029100.062
microtubule based movementGO:0007018330.062
embryonic skeletal system developmentGO:0048706970.062
embryonic organ morphogenesisGO:00485622740.061
epithelial cell differentiationGO:00308551160.060
determination of left right symmetryGO:00073681790.060
cell matrix adhesionGO:000716040.060
ovulation cycleGO:004269820.057
epithelium migrationGO:0090132250.057
signal transductionGO:00071654550.057
p38mapk cascadeGO:003806610.056
regulation of localizationGO:00328791040.056
regulation of endothelial cell differentiationGO:004560130.055
organic cyclic compound metabolic processGO:19013603010.055
embryonic skeletal system morphogenesisGO:0048704930.054
determination of heart left right asymmetryGO:00613711170.054
positive regulation of cellular processGO:00485222010.054
cellular component assemblyGO:00226071700.054
polarized epithelial cell differentiationGO:003085940.054
neuron projection developmentGO:00311751800.054
regulation of cellular component organizationGO:0051128860.053
regulation of heart growthGO:006042020.053
positive regulation of cellular component biogenesisGO:004408930.053
macromolecule modificationGO:00434121110.053
regulation of cell morphogenesis involved in differentiationGO:0010769380.052
microtubule based processGO:0007017600.052
endocrine system developmentGO:0035270650.052
cellular component morphogenesisGO:00329893360.052
neuron projection extensionGO:1990138450.052
positive regulation of endothelial cell migrationGO:001059520.051
regulation of organ morphogenesisGO:2000027350.051
biological adhesionGO:0022610400.051
embryonic viscerocranium morphogenesisGO:0048703520.051
cellular protein metabolic processGO:00442671290.051
striated muscle cell differentiationGO:00511461290.051
camera type eye developmentGO:00430102220.051
regulation of cell shapeGO:000836010.051
gland developmentGO:00487321430.050
nucleobase containing compound biosynthetic processGO:00346542050.050
regulation of receptor mediated endocytosisGO:004825940.050
establishment of organelle localizationGO:0051656450.049
negative regulation of protein phosphorylationGO:000193340.049
response to arsenic containing substanceGO:004668550.049
embryonic cranial skeleton morphogenesisGO:0048701900.048
actin filament organizationGO:0007015150.047
mechanosensory lateral line system developmentGO:0048881490.047
digestive system developmentGO:00551232890.047
transportGO:00068102200.047
rna biosynthetic processGO:00327741810.046
regulation of response to stimulusGO:00485832690.046
morphogenesis of a branching structureGO:0001763210.046
glomerular filtrationGO:000309460.046
organelle organizationGO:00069962270.045
immune system processGO:00023762410.045
regulation of rna metabolic processGO:00512522240.045
regulation of cell morphogenesisGO:0022604420.045
positive regulation of macromolecule metabolic processGO:0010604930.045
myeloid cell differentiationGO:0030099860.045
pigment granule localizationGO:0051875250.044
action potentialGO:0001508190.044
cellular response to organic substanceGO:00713101050.044
regulation of cell growthGO:0001558290.043
establishment of localization in cellGO:0051649770.043
skeletal muscle fiber developmentGO:0048741350.043
spermatid developmentGO:000728620.043
regulation of nitrogen compound metabolic processGO:00511712510.043
lymphangiogenesisGO:0001946250.043
positive regulation of biological processGO:00485182530.042
segmentationGO:0035282970.041
establishment of vesicle localizationGO:0051650240.041
positive regulation of cell adhesionGO:004578510.041
cell substrate junction assemblyGO:000704420.041
epithelial cell developmentGO:0002064420.041
muscle tissue developmentGO:00605371100.040
mesenchyme developmentGO:00604851270.040
regulation of retina development in camera type eyeGO:190286620.040
membrane repolarizationGO:008600920.040
endothelial cell proliferationGO:0001935110.040
positive regulation of metabolic processGO:00098931080.040
phosphorus metabolic processGO:00067931090.040
positive regulation of cell substrate adhesionGO:001081110.040
gene expressionGO:00104672520.039
regulation of angiogenesisGO:0045765260.039
growthGO:00400071740.039
cell junction organizationGO:0034330110.038
striated muscle tissue developmentGO:00147061100.037
aromatic compound biosynthetic processGO:00194382170.037
cardiac cell fate commitmentGO:006091110.037
organic substance biosynthetic processGO:19015762890.037
organic cyclic compound biosynthetic processGO:19013622230.037
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.037
apoptotic process involved in developmentGO:190274220.037
ovulation cycle processGO:002260220.036
transmembrane transportGO:00550851200.036
cartilage developmentGO:0051216960.036
regulation of organ growthGO:004662030.036
positive regulation of epithelial cell proliferationGO:005067910.036
negative regulation of stem cell differentiationGO:200073720.036
single organism cellular localizationGO:1902580460.036
cellular response to chemical stimulusGO:00708871570.035
ion transmembrane transportGO:0034220910.035
regulation of macromolecule biosynthetic processGO:00105562250.035
protein modification processGO:00362111000.035
embryonic heart tube developmentGO:00350501330.035
phosphate containing compound metabolic processGO:00067961080.035
eye morphogenesisGO:00485921440.035
vesicle localizationGO:0051648270.035
regulation of cellular biosynthetic processGO:00313262450.034
cognitionGO:005089010.034
smooth muscle contractionGO:000693920.034
cilium organizationGO:0044782710.034
phosphorylationGO:0016310690.033
renal system vasculature developmentGO:006143720.033
monocyte differentiationGO:003022420.033
cell migrationGO:00164772370.032
specification of symmetryGO:00097992040.032
erythrocyte homeostasisGO:0034101550.032
hemopoiesisGO:00300971830.032
regulation of cardiac muscle tissue developmentGO:005502410.032
regulation of gene expressionGO:00104682650.032
cellular nitrogen compound biosynthetic processGO:00442712180.032
convergent extensionGO:00600261180.032
muscle structure developmentGO:00610611960.031
multi organism processGO:00517041340.031
spermatid differentiationGO:004851520.031
positive regulation of cellular biosynthetic processGO:0031328680.031
exocrine system developmentGO:0035272280.031
regulation of neuron differentiationGO:0045664560.031
outflow tract morphogenesisGO:000315110.031
cellular macromolecule biosynthetic processGO:00346452240.030
defense responseGO:0006952470.030
granulocyte chemotaxisGO:0071621110.030
neuromuscular synaptic transmissionGO:000727420.030
neuron projection guidanceGO:0097485860.030
regulation of endothelial cell proliferationGO:000193610.030
single organism organelle organizationGO:19025891990.029
cilium movementGO:0003341260.029
positive regulation of embryonic developmentGO:004001930.029
muscle cell developmentGO:00550011150.029
skeletal system morphogenesisGO:00487051020.029
response to hydrogen peroxideGO:004254230.029
tissue homeostasisGO:0001894250.029
extracellular matrix assemblyGO:008502910.029
multicellular organism growthGO:003526440.029
cellular protein complex assemblyGO:0043623190.029
response to carbohydrateGO:000974330.029
positive regulation of erk1 and erk2 cascadeGO:007037420.028
tissue migrationGO:0090130370.028
nucleobase containing compound metabolic processGO:00061392740.028
glomerular epithelial cell fate commitmentGO:007231440.028
rhombomere boundary formationGO:0021654100.028
glomerulus vasculature developmentGO:007201220.028
eye photoreceptor cell differentiationGO:0001754450.028
primitive hemopoiesisGO:0060215270.028
taxisGO:00423301090.027
stem cell proliferationGO:007208940.027
epithelial cell morphogenesisGO:000338220.027
regulation of programmed cell deathGO:00430671010.027
endocardium morphogenesisGO:000316040.027
heterocycle biosynthetic processGO:00181302150.027
carboxylic acid metabolic processGO:0019752220.027
membrane organizationGO:0061024210.027
reproductive processGO:0022414400.027
embryonic heart tube morphogenesisGO:00031431080.027
notch signaling pathwayGO:0007219350.027
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.027
embryo development ending in birth or egg hatchingGO:00097922710.026
negative regulation of developmental processGO:0051093650.026
blood vessel developmentGO:00015682460.026
glomerular epithelial cell developmentGO:007231080.026
rhombomere formationGO:0021594120.026
deathGO:00162651210.026
mesoderm developmentGO:0007498880.026
rna metabolic processGO:00160702190.026
digestive tract developmentGO:00485652650.026
glomerular epithelium developmentGO:0072010120.025
regionalizationGO:00030022740.025
single organism nuclear importGO:190259330.025
stem cell developmentGO:0048864820.025
positive regulation of transportGO:005105020.025
extracellular matrix organizationGO:0030198270.025
reflexGO:006000420.025
adrenal gland developmentGO:0030325100.025
regulation of neurogenesisGO:0050767870.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.025
brain developmentGO:00074202930.025
apoptotic processGO:00069151160.025
response to biotic stimulusGO:0009607970.025
kidney vasculature developmentGO:006144020.025
chondrocyte developmentGO:000206340.025
regulation of protein kinase b signalingGO:005189680.025
positive regulation of signal transductionGO:0009967560.024
regulation of vasculature developmentGO:1901342330.024
macromolecule localizationGO:0033036540.024
regulation of cell substrate adhesionGO:001081010.024
adult behaviorGO:003053420.024
regulation of actin cytoskeleton organizationGO:003295680.024
female sex differentiationGO:004666040.024
regulation of cell migrationGO:0030334400.024
fertilizationGO:000956630.024
heterocycle metabolic processGO:00464832900.024
cellular response to external stimulusGO:007149620.024
nucleic acid templated transcriptionGO:00976591810.024
cellular ketone metabolic processGO:0042180110.024
lateral line system developmentGO:0048925760.024
negative regulation of nuclear divisionGO:005178430.023
regulation of cellular metabolic processGO:00313233200.023
regulation of erk1 and erk2 cascadeGO:007037240.023
thyroid gland developmentGO:0030878120.023
regulation of cellular amino acid metabolic processGO:000652100.023
positive regulation of biosynthetic processGO:0009891680.023
tissue remodelingGO:004877140.023
response to endogenous stimulusGO:0009719830.023
neural crest cell differentiationGO:0014033720.023
single organism cell adhesionGO:0098602290.023
protein localization to membraneGO:007265790.023
regulation of establishment of protein localizationGO:007020140.023
negative regulation of multicellular organismal processGO:0051241690.023
regulation of protein metabolic processGO:0051246560.022
regulation of transcription dna templatedGO:00063552130.022
positive regulation of endothelial cell differentiationGO:004560320.022
regulation of cellular ketone metabolic processGO:001056570.022
cardiogenic plate morphogenesisGO:000314210.022
heart loopingGO:0001947940.022
development of primary female sexual characteristicsGO:004654540.022
monoamine transportGO:001584410.022
regulation of p38mapk cascadeGO:190074410.022
regulation of cell projection organizationGO:0031344440.022
actin cytoskeleton organizationGO:0030036630.022
positive regulation of gene expressionGO:0010628710.022
myelination of posterior lateral line nerve axonsGO:004893250.022
organelle localizationGO:0051640490.022
cellular protein modification processGO:00064641000.022
regulation of jak stat cascadeGO:004642530.021
regulation of peptidyl tyrosine phosphorylationGO:005073010.021
regulation of cell deathGO:00109411030.021
positive regulation of macromolecule biosynthetic processGO:0010557590.021
cellular component disassemblyGO:002241110.021
establishment of pigment granule localizationGO:0051905220.021
macromolecule biosynthetic processGO:00090592270.021
skeletal muscle tissue developmentGO:0007519670.021
response to monosaccharideGO:003428430.021
protein complex subunit organizationGO:0071822460.021
axon developmentGO:00615641660.020
regulation of cellular component movementGO:0051270550.020
positive regulation of rna metabolic processGO:0051254590.020
zymogen activationGO:003163830.020
single organismal cell cell adhesionGO:0016337290.020
positive regulation of cytokine productionGO:000181920.020
specification of axis polarityGO:006500140.020
response to abiotic stimulusGO:00096281220.020
pigment granule aggregation in cell centerGO:005187780.020
regulation of catalytic activityGO:0050790550.020
positive regulation of epithelial cell migrationGO:001063420.020
secondary metabolic processGO:001974830.020
regulation of neuron projection developmentGO:0010975400.019
regulation of response to external stimulusGO:0032101310.019
actin filament based processGO:0030029640.019
regulation of transportGO:0051049450.019
cell cell junction organizationGO:0045216100.019
negative regulation of cell communicationGO:0010648960.019
amine metabolic processGO:000930820.019
negative regulation of macromolecule metabolic processGO:0010605760.019
positive regulation of jak stat cascadeGO:004642720.019
morphogenesis of a branching epitheliumGO:0061138160.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
regulation of apoptotic processGO:0042981980.019
positive regulation of catabolic processGO:000989640.019
regulation of systemic arterial blood pressureGO:000307310.019
cell deathGO:00082191210.019
organic acid metabolic processGO:0006082310.019
neuron recognitionGO:0008038180.019
regulation of cellular protein metabolic processGO:0032268520.019
negative regulation of metabolic processGO:0009892860.019
somitogenesisGO:0001756870.019
kidney morphogenesisGO:0060993150.019
regulation of cell communicationGO:00106462320.019
regulation of cell motilityGO:2000145460.019
synaptic vesicle transportGO:004848910.019
heart morphogenesisGO:00030071560.019
sensory organ morphogenesisGO:00905962000.019
negative regulation of kinase activityGO:003367340.018
sensory perception of chemical stimulusGO:000760630.018
axis specificationGO:0009798430.018
regulation of dendrite developmentGO:005077330.018
negative regulation of wnt signaling pathwayGO:0030178300.018
meiotic chromosome segregationGO:004513230.018
regulation of stem cell differentiationGO:200073640.018
protein import into nucleusGO:000660630.018
stem cell differentiationGO:00488631170.018
response to nicotineGO:003509420.018
regulation of membrane potentialGO:0042391230.018
positive regulation of nucleic acid templated transcriptionGO:1903508570.018
macromolecular complex subunit organizationGO:0043933740.018
sprouting angiogenesisGO:0002040530.018
negative regulation of programmed cell deathGO:0043069580.018
cellular localizationGO:0051641970.018
nuclear importGO:005117030.018
oxoacid metabolic processGO:0043436310.018
negative regulation of signal transductionGO:0009968940.017
odontogenesis of dentin containing toothGO:004247510.017
camera type eye morphogenesisGO:00485931080.017
cardiocyte differentiationGO:0035051440.017
cation transmembrane transportGO:0098655650.017
regulation of microtubule cytoskeleton organizationGO:007050730.017
stem cell maintenanceGO:001982740.017
circulatory system processGO:0003013870.017
transcription dna templatedGO:00063511810.017
chemotaxisGO:00069351040.017
cell type specific apoptotic processGO:0097285220.017
response to oxygen containing compoundGO:1901700550.017
regulation of cellular amine metabolic processGO:003323800.017
cellular response to decreased oxygen levelsGO:003629410.017
receptor internalizationGO:003162320.017
hindbrain morphogenesisGO:0021575220.017
negative regulation of feeding behaviorGO:200025220.017
myeloid cell homeostasisGO:0002262560.016
cell projection assemblyGO:0030031640.016
venous blood vessel developmentGO:006084190.016
osteoclast differentiationGO:003031610.016
regulation of biosynthetic processGO:00098892500.016
photoreceptor cell differentiationGO:0046530550.016
positive regulation of cellular metabolic processGO:0031325940.016
regulation of actin filament based processGO:003297090.016
regulation of reactive oxygen species metabolic processGO:200037720.016
erk1 and erk2 cascadeGO:007037140.016
positive regulation of cellular amine metabolic processGO:003324000.016
forebrain regionalizationGO:002187140.016
membrane invaginationGO:001032410.016
positive regulation of peptidase activityGO:0010952100.016
nucleocytoplasmic transportGO:000691340.016
signal transduction by phosphorylationGO:0023014180.016
positive regulation of canonical wnt signaling pathwayGO:009026340.016
multicellular organismal reproductive processGO:0048609350.016
negative regulation of reproductive processGO:200024230.016
cellular amino acid metabolic processGO:000652070.015
phagocytosisGO:000690930.015
positive regulation of leukocyte migrationGO:000268720.015
regulation of muscle tissue developmentGO:190186160.015
inner ear receptor cell fate commitmentGO:006012040.015
negative regulation of cell deathGO:0060548600.015
erythrocyte differentiationGO:0030218540.015
lymph vessel developmentGO:0001945270.015
positive regulation of nucleobase containing compound metabolic processGO:0045935690.015
leukocyte chemotaxisGO:0030595120.015
somite developmentGO:0061053960.015
neuron fate determinationGO:004866420.015
cellular macromolecular complex assemblyGO:0034622240.015
germ line stem cell maintenanceGO:003071820.015
mitotic cell cycle processGO:1903047480.015
neurological system processGO:0050877620.015
cell adhesion mediated by integrinGO:003362710.015
auditory receptor cell fate commitmentGO:000991240.015
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.015
cellular response to hypoxiaGO:007145610.015
positive regulation of cell communicationGO:0010647560.015
protein targeting to nucleusGO:004474430.015
nucleic acid metabolic processGO:00903042440.015
glucose importGO:004632320.015

nphs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.443
urinary system diseaseDOID:1800.443
kidney diseaseDOID:55700.186
bone diseaseDOID:008000100.023
connective tissue diseaseDOID:6500.023
bone development diseaseDOID:008000600.023
musculoskeletal system diseaseDOID:1700.023
cancerDOID:16200.021
disease of cellular proliferationDOID:1456600.021
organ system cancerDOID:005068600.019