Danio rerio

0 known processes

idh2

isocitrate dehydrogenase 2 (NADP+), mitochondrial

(Aliases: zgc:55485,wu:fb33c06,wu:fq43b01,wu:fk31e05)

idh2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.619
embryo development ending in birth or egg hatchingGO:00097922710.413
mitochondrion organizationGO:000700540.277
nitrogen compound metabolic processGO:00068073190.251
agingGO:000756820.189
carbohydrate derivative metabolic processGO:1901135610.173
nucleobase containing compound metabolic processGO:00061392740.162
organophosphate metabolic processGO:0019637370.159
atp synthesis coupled electron transportGO:004277310.151
ribonucleotide metabolic processGO:0009259270.149
single organism organelle organizationGO:19025891990.132
ribose phosphate metabolic processGO:0019693270.127
maintenance of locationGO:005123540.122
response to drugGO:004249330.122
establishment of localizationGO:00512342440.119
ribonucleotide biosynthetic processGO:0009260200.119
heterocycle metabolic processGO:00464832900.110
small molecule metabolic processGO:0044281770.110
purine ribonucleoside monophosphate metabolic processGO:000916750.110
purine nucleotide metabolic processGO:0006163270.106
ribonucleoside metabolic processGO:0009119110.105
organonitrogen compound metabolic processGO:1901564740.104
cellular nitrogen compound metabolic processGO:00346412900.098
carbohydrate derivative biosynthetic processGO:1901137430.091
cellular aromatic compound metabolic processGO:00067252950.087
lipid storageGO:001991510.086
purine nucleoside monophosphate catabolic processGO:000912840.085
mitochondrial atp synthesis coupled electron transportGO:004277510.084
single organism metabolic processGO:00447102170.083
cellular biosynthetic processGO:00442492860.082
response to chemicalGO:00422213200.081
organic cyclic compound metabolic processGO:19013603010.080
transportGO:00068102200.079
central nervous system developmentGO:00074173870.075
organophosphate biosynthetic processGO:0090407230.075
atp catabolic processGO:000620040.069
reactive oxygen species metabolic processGO:007259360.066
organic substance biosynthetic processGO:19015762890.064
regulation of metabolic processGO:00192223590.064
oxidative phosphorylationGO:000611910.064
purine ribonucleoside monophosphate catabolic processGO:000916940.064
positive regulation of transportGO:005105020.063
biosynthetic processGO:00090582940.062
phototransductionGO:000760220.062
single organism localizationGO:19025782250.062
oocyte anterior posterior axis specificationGO:000731440.061
phosphate containing compound metabolic processGO:00067961080.059
gtp metabolic processGO:004603940.058
nucleoside phosphate metabolic processGO:0006753280.057
electron transport chainGO:002290020.057
nucleoside monophosphate catabolic processGO:000912540.056
spermatid developmentGO:000728620.053
response to stressGO:00069502630.052
reproductionGO:0000003400.051
organic acid metabolic processGO:0006082310.051
regulation of biological qualityGO:00650082630.047
spermatid differentiationGO:004851520.047
phosphorus metabolic processGO:00067931090.045
regulation of nucleobase containing compound metabolic processGO:00192192500.044
response to external stimulusGO:00096052640.043
regulation of protein transportGO:005122330.042
nucleobase containing small molecule metabolic processGO:0055086320.042
regulation of gene expressionGO:00104682650.042
ribonucleoside monophosphate catabolic processGO:000915840.041
purine containing compound biosynthetic processGO:0072522200.041
guanosine containing compound metabolic processGO:190106840.041
phosphorylationGO:0016310690.041
negative regulation of protein phosphorylationGO:000193340.040
ribose phosphate biosynthetic processGO:0046390200.039
organic cyclic compound biosynthetic processGO:19013622230.039
multi organism processGO:00517041340.038
regulation of establishment of protein localizationGO:007020140.038
single fertilizationGO:000733830.038
amine metabolic processGO:000930820.037
locomotionGO:00400113130.037
negative regulation of biological processGO:00485193040.037
response to organic substanceGO:00100331530.036
response to abiotic stimulusGO:00096281220.036
phagocytosisGO:000690930.036
regulation of bindingGO:005109830.035
head developmentGO:00603223030.035
purine nucleoside triphosphate biosynthetic processGO:000914520.034
mitochondrial electron transport nadh to ubiquinoneGO:000612010.033
striated muscle cell differentiationGO:00511461290.032
gene expressionGO:00104672520.032
nucleobase containing compound biosynthetic processGO:00346542050.031
regulation of biosynthetic processGO:00098892500.030
cellular amine metabolic processGO:004410620.030
nucleotide metabolic processGO:0009117280.030
purine ribonucleoside biosynthetic processGO:004612920.030
cellular respirationGO:004533330.030
cellular nitrogen compound biosynthetic processGO:00442712180.030
regulation of cellular amine metabolic processGO:003323800.029
cell cell recognitionGO:000998810.029
cell cycleGO:0007049930.029
regulation of blood pressureGO:000821710.029
atp metabolic processGO:004603450.028
muscle structure developmentGO:00610611960.028
organelle organizationGO:00069962270.028
establishment of protein localization to organelleGO:007259440.028
cellular protein complex assemblyGO:0043623190.027
positive regulation of catabolic processGO:000989640.027
cell deathGO:00082191210.027
growthGO:00400071740.026
single organism transportGO:00447652060.026
cellular macromolecule metabolic processGO:00442603910.026
regulation of intracellular protein transportGO:003315730.025
protein secretionGO:000930610.025
nucleoside biosynthetic processGO:000916320.025
nucleoside phosphate biosynthetic processGO:1901293210.024
nucleoside triphosphate biosynthetic processGO:000914220.024
purine containing compound metabolic processGO:0072521290.024
nucleotide biosynthetic processGO:0009165210.024
nitric oxide metabolic processGO:004620920.023
regulation of developmental processGO:00507932470.023
positive regulation of cellular catabolic processGO:003133130.023
transmembrane transportGO:00550851200.023
purine nucleotide biosynthetic processGO:0006164200.023
positive regulation of apoptotic signaling pathwayGO:200123510.023
macromolecule modificationGO:00434121110.023
protein polymerizationGO:005125840.023
ion transportGO:00068111140.022
macromolecule biosynthetic processGO:00090592270.022
protein complex subunit organizationGO:0071822460.022
cellular macromolecule biosynthetic processGO:00346452240.022
regulation of cellular ketone metabolic processGO:001056570.022
cellular component assemblyGO:00226071700.022
nucleoside metabolic processGO:0009116110.022
cell surface receptor signaling pathwayGO:00071663250.022
regulation of membrane potentialGO:0042391230.022
embryonic organ morphogenesisGO:00485622740.022
apoptotic processGO:00069151160.021
membrane fusionGO:006102520.021
regulation of endothelial cell proliferationGO:000193610.021
translational initiationGO:000641330.021
negative regulation of kinase activityGO:003367340.021
microtubule based processGO:0007017600.021
regulation of mrna splicing via spliceosomeGO:004802430.021
purine ribonucleoside triphosphate metabolic processGO:000920590.021
regulation of cell activationGO:005086510.021
brain developmentGO:00074202930.021
protein importGO:001703830.020
striated muscle cell developmentGO:00550021080.020
chordate embryonic developmentGO:00430092710.020
negative regulation of protein kinase activityGO:000646940.020
oxoacid metabolic processGO:0043436310.020
positive regulation of secretionGO:005104710.020
cellular component morphogenesisGO:00329893360.020
regulation of cellular amino acid metabolic processGO:000652100.019
embryonic organ developmentGO:00485683810.019
cellular response to biotic stimulusGO:007121630.019
multicellular organism growthGO:003526440.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
programmed cell deathGO:00125011190.019
tissue regenerationGO:0042246740.019
organonitrogen compound biosynthetic processGO:1901566470.018
cellular ketone metabolic processGO:0042180110.018
purine ribonucleoside metabolic processGO:0046128100.018
nuclear migrationGO:000709730.018
purine ribonucleotide metabolic processGO:0009150270.018
regulation of alternative mrna splicing via spliceosomeGO:000038110.018
internal protein amino acid acetylationGO:000647520.017
determination of bilateral symmetryGO:00098552040.017
immune system processGO:00023762410.017
positive regulation of secretion by cellGO:190353210.017
regulation of macromolecule biosynthetic processGO:00105562250.017
nucleoside monophosphate metabolic processGO:000912360.017
muscle cell developmentGO:00550011150.017
regulation of protein catabolic processGO:004217610.017
organelle fusionGO:004828430.017
leukocyte proliferationGO:007066110.017
guanosine containing compound catabolic processGO:190106920.017
regulation of protein localization to nucleusGO:190018020.017
protein acetylationGO:000647320.016
regulation of primary metabolic processGO:00800903110.016
developmental growthGO:00485891660.016
negative regulation of macromolecule metabolic processGO:0010605760.016
rna metabolic processGO:00160702190.016
stem cell maintenanceGO:001982740.016
sexual reproductionGO:0019953360.016
multi organism reproductive processGO:0044703360.016
apical junction assemblyGO:004329710.016
heterocycle biosynthetic processGO:00181302150.016
heart developmentGO:00075073130.016
positive regulation of nucleoside metabolic processGO:004597910.016
purine ribonucleotide biosynthetic processGO:0009152200.016
regulation of receptor activityGO:001046920.016
regulation of nucleoside metabolic processGO:000911820.016
regulation of protein targetingGO:190353320.016
ribonucleoside triphosphate biosynthetic processGO:000920120.016
single organism biosynthetic processGO:0044711710.015
regulation of protein complex assemblyGO:004325430.015
cytokinesisGO:000091030.015
mitotic dna damage checkpointGO:004477340.015
regulation of protein ubiquitinationGO:003139630.015
action potentialGO:0001508190.015
regulation of multicellular organismal processGO:00512392770.015
aromatic compound biosynthetic processGO:00194382170.015
nuclear transportGO:005116940.015
inner ear developmentGO:00488391260.015
dorsal ventral pattern formationGO:00099531250.015
regulation of circadian rhythmGO:004275240.015
carboxylic acid metabolic processGO:0019752220.015
germ line stem cell maintenanceGO:003071820.015
muscle tissue developmentGO:00605371100.015
carbohydrate biosynthetic processGO:001605110.015
regulation of purine nucleotide catabolic processGO:003312120.015
regulation of cytokine productionGO:000181730.015
multicellular organismal reproductive processGO:0048609350.015
ribonucleoside biosynthetic processGO:004245520.014
regulation of gtp catabolic processGO:003312420.014
positive regulation of nucleotide catabolic processGO:003081310.014
regulation of metal ion transportGO:001095940.014
negative regulation of metabolic processGO:0009892860.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
adult behaviorGO:003053420.014
reactive nitrogen species metabolic processGO:200105700.014
protein stabilizationGO:005082120.014
purine nucleoside monophosphate metabolic processGO:000912650.014
rna localizationGO:000640340.014
angiogenesisGO:00015251580.014
regulation of mrna processingGO:005068430.014
gtp catabolic processGO:000618420.014
cytoskeleton organizationGO:0007010960.014
regulation of multicellular organism growthGO:004001440.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
response to hypoxiaGO:0001666250.014
neurotransmitter transportGO:000683620.014
regulation of reproductive processGO:200024140.014
multicellular organismal signalingGO:0035637220.014
single organism membrane fusionGO:004480120.014
cellular amino acid metabolic processGO:000652070.014
fertilizationGO:000956630.014
macromolecule localizationGO:0033036540.014
regulation of protein bindingGO:004339330.014
macromolecular complex subunit organizationGO:0043933740.013
response to coldGO:000940940.013
multicellular organismal metabolic processGO:004423620.013
regulation of nitrogen compound metabolic processGO:00511712510.013
multicellular organism reproductionGO:0032504350.013
cellular protein metabolic processGO:00442671290.013
cell migrationGO:00164772370.013
response to woundingGO:00096111160.013
microtubule cytoskeleton organization involved in mitosisGO:190285010.013
purine ribonucleoside triphosphate biosynthetic processGO:000920620.013
ribonucleoside monophosphate metabolic processGO:000916150.013
cellular component disassemblyGO:002241110.013
regulation of apoptotic processGO:0042981980.013
positive regulation of cellular amine metabolic processGO:003324000.013
positive regulation of dna metabolic processGO:005105410.013
nucleic acid metabolic processGO:00903042440.013
reactive oxygen species biosynthetic processGO:190340910.012
glial cell differentiationGO:0010001420.012
regulation of cellular protein catabolic processGO:190336210.012
regulation of cell shapeGO:000836010.012
pole plasm assemblyGO:000731540.012
nucleocytoplasmic transportGO:000691340.012
stem cell proliferationGO:007208940.012
transcription dna templatedGO:00063511810.012
protein complex assemblyGO:0006461300.012
mitotic dna integrity checkpointGO:004477440.012
nuclear exportGO:005116810.012
negative regulation of molecular functionGO:0044092230.012
purine nucleoside biosynthetic processGO:004245120.012
regulation of sodium ion transportGO:000202820.012
cellular protein modification processGO:00064641000.012
negative regulation of catalytic activityGO:0043086210.012
system processGO:00030081850.012
regulation of macromolecule metabolic processGO:00602553170.012
nucleic acid transportGO:005065720.011
regulation of programmed cell deathGO:00430671010.011
regenerationGO:0031099910.011
response to endogenous stimulusGO:0009719830.011
spindle assembly involved in mitosisGO:009030710.011
neuronal action potentialGO:0019228180.011
regulation of cytoplasmic transportGO:190364940.011
activation of mapk activityGO:000018730.011
protein complex biogenesisGO:0070271300.011
b cell activationGO:004211320.011
glycosyl compound biosynthetic processGO:190165920.011
cell motilityGO:00488702440.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
muscle cell differentiationGO:00426921390.011
response to lipidGO:0033993600.011
eye developmentGO:00016542770.011
insulin like growth factor receptor signaling pathwayGO:004800940.011
reproductive processGO:0022414400.011
response to external biotic stimulusGO:0043207970.011
regulation of reactive oxygen species metabolic processGO:200037720.011
g protein coupled receptor signaling pathwayGO:0007186740.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
organelle assemblyGO:00709251100.011
signal transductionGO:00071654550.011
negative regulation of epithelial cell proliferationGO:005068010.011
mitotic cell cycleGO:0000278640.011
mononuclear cell proliferationGO:003294310.011
cell migration involved in gastrulationGO:0042074790.011
deathGO:00162651210.011
establishment of rna localizationGO:005123630.011
macromolecular complex disassemblyGO:003298410.011
regulation of actin filament based movementGO:190311510.011
cellular response to external stimulusGO:007149620.011
cellular carbohydrate metabolic processGO:004426240.011
striated muscle tissue developmentGO:00147061100.011
determination of left right symmetryGO:00073681790.011
response to decreased oxygen levelsGO:0036293250.011
regulation of cell deathGO:00109411030.011
wound healingGO:0042060900.011
nitric oxide biosynthetic processGO:000680920.011
response to organic cyclic compoundGO:0014070510.011
carbohydrate homeostasisGO:003350010.010
response to oxygen levelsGO:0070482250.010
connective tissue developmentGO:0061448990.010
transmission of nerve impulseGO:0019226190.010
regulation of muscle contractionGO:000693730.010
ubiquitin dependent protein catabolic processGO:000651130.010
maternal determination of anterior posterior axis embryoGO:000835840.010
circulatory system processGO:0003013870.010
response to biotic stimulusGO:0009607970.010
adherens junction organizationGO:003433240.010
posttranscriptional regulation of gene expressionGO:0010608140.010
rna transportGO:005065820.010
regulation of gtpase activityGO:004308720.010
positive regulation of purine nucleotide catabolic processGO:003312310.010
developmental process involved in reproductionGO:0003006270.010
regionalizationGO:00030022740.010
cell cycle g2 m phase transitionGO:004483940.010
glial cell proliferationGO:001400940.010
proepicardium developmentGO:000334240.010
cytoplasm organizationGO:000702840.010
regulation of wound healingGO:006104120.010
regulation of epithelial cell proliferationGO:005067830.010

idh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.017
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
disease of anatomical entityDOID:700.014