Danio rerio

18 known processes

manf

mesencephalic astrocyte-derived neurotrophic factor

(Aliases: im:6909481,MGC153327,zgc:153327)

manf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to topologically incorrect proteinGO:003596720.976
response to unfolded proteinGO:000698620.918
cellular response to unfolded proteinGO:003462020.877
endoplasmic reticulum unfolded protein responseGO:003096820.856
er nucleus signaling pathwayGO:000698420.837
response to topologically incorrect proteinGO:003596620.681
regulation of nuclease activityGO:003206910.585
response to endoplasmic reticulum stressGO:003497660.428
protein n linked glycosylationGO:000648710.341
cellular response to organic substanceGO:00713101050.340
larval developmentGO:000216420.304
positive regulation of apoptotic signaling pathwayGO:200123510.299
response to organic substanceGO:00100331530.265
ceramide biosynthetic processGO:004651310.251
locomotionGO:00400113130.202
regulation of multicellular organismal processGO:00512392770.170
agingGO:000756820.161
chromosome organization involved in meiosisGO:007019210.148
response to amineGO:001407510.139
programmed cell deathGO:00125011190.122
positive regulation of nuclease activityGO:003207510.119
signal transductionGO:00071654550.118
cellular response to chemical stimulusGO:00708871570.115
hydrogen peroxide metabolic processGO:004274320.113
cellular response to stressGO:0033554620.106
response to abiotic stimulusGO:00096281220.102
embryonic organ developmentGO:00485683810.101
cellular response to antibioticGO:007123610.100
membrane lipid biosynthetic processGO:004646720.097
regulation of dna catabolic processGO:190362410.095
positive regulation of biological processGO:00485182530.087
cellular component assemblyGO:00226071700.084
dicarboxylic acid metabolic processGO:004364810.083
cellular protein metabolic processGO:00442671290.082
maintenance of locationGO:005123540.081
cell proliferationGO:0008283800.080
response to chemicalGO:00422213200.074
cell deathGO:00082191210.072
cell migrationGO:00164772370.070
extrinsic apoptotic signaling pathwayGO:009719130.068
regulation of cell deathGO:00109411030.065
protein metabolic processGO:00195381830.064
regulation of signalingGO:00230512350.062
regulation of protein ubiquitinationGO:003139630.059
response to temperature stimulusGO:0009266150.057
regulation of developmental processGO:00507932470.054
morphogenesis of an epitheliumGO:00020093330.053
cell substrate junction assemblyGO:000704420.052
modification dependent macromolecule catabolic processGO:004363230.052
single organism localizationGO:19025782250.051
digestive tract morphogenesisGO:00485462310.050
cellular response to toxic substanceGO:009723710.048
response to stressGO:00069502630.042
regulation of molecular functionGO:0065009700.042
spindle assemblyGO:005122520.041
multicellular organism growthGO:003526440.040
endodermal digestive tract morphogenesisGO:006103120.039
positive regulation of cellular processGO:00485222010.039
deathGO:00162651210.036
central nervous system developmentGO:00074173870.036
regulation of protein modification by small protein conjugation or removalGO:190332030.036
cellular protein catabolic processGO:004425740.035
regulation of nucleotide catabolic processGO:003081120.034
embryo development ending in birth or egg hatchingGO:00097922710.034
phosphorylationGO:0016310690.033
response to heatGO:000940860.033
embryonic organ morphogenesisGO:00485622740.033
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.033
regulation of nucleoside metabolic processGO:000911820.032
organic substance catabolic processGO:1901575280.031
retina homeostasisGO:0001895120.030
modification dependent protein catabolic processGO:001994130.030
regulation of epithelial cell proliferationGO:005067830.030
single organism transportGO:00447652060.030
sphingolipid biosynthetic processGO:003014820.029
cellular component morphogenesisGO:00329893360.028
regulation of extrinsic apoptotic signaling pathwayGO:200123630.028
cellular localizationGO:0051641970.027
retrograde axon cargo transportGO:000809010.026
cellular component biogenesisGO:00440851780.026
cellular response to extracellular stimulusGO:003166820.025
regulation of apoptotic processGO:0042981980.025
regulation of gtp catabolic processGO:003312420.025
sensory organ developmentGO:00074233930.025
proteolysis involved in cellular protein catabolic processGO:005160330.024
chordate embryonic developmentGO:00430092710.024
cellular response to nutrient levelsGO:003166920.024
regulation of cell communicationGO:00106462320.024
regulation of purine nucleotide catabolic processGO:003312120.023
immune system developmentGO:00025201910.023
heart developmentGO:00075073130.023
transportGO:00068102200.023
digestive system developmentGO:00551232890.022
organonitrogen compound metabolic processGO:1901564740.022
positive regulation of cytokine productionGO:000181920.022
regulation of cell activationGO:005086510.022
lipid homeostasisGO:005508830.022
lipid storageGO:001991510.022
photoreceptor cell differentiationGO:0046530550.021
regulation of biological qualityGO:00650082630.021
Mouse
response to amphetamineGO:000197510.021
cellular response to oxygen radicalGO:007145020.021
specification of symmetryGO:00097992040.021
regulation of cytokine productionGO:000181730.021
regulation of gtpase activityGO:004308720.021
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.020
brain developmentGO:00074202930.020
regulation of nucleotide metabolic processGO:0006140170.020
meiotic nuclear divisionGO:000712640.020
regulation of catalytic activityGO:0050790550.019
regulation of signal transductionGO:00099662250.019
peptide transportGO:001583310.018
regulation of microtubule based movementGO:006063230.018
cell morphogenesisGO:00009022890.018
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.018
amine metabolic processGO:000930820.018
regulation of programmed cell deathGO:00430671010.017
negative regulation of cellular processGO:00485232830.017
ubiquitin dependent protein catabolic processGO:000651130.017
protein targeting to membraneGO:000661210.017
regulation of phosphorus metabolic processGO:0051174430.017
cellular response to starvationGO:000926710.017
cellular protein modification processGO:00064641000.016
regulation of cytokine mediated signaling pathwayGO:000195930.016
skeletal system developmentGO:00015011810.016
transmembrane transportGO:00550851200.016
negative regulation of biological processGO:00485193040.016
toxin transportGO:190199820.016
regulation of phosphate metabolic processGO:0019220430.016
ceramide metabolic processGO:000667250.016
golgi vesicle transportGO:004819330.016
negative regulation of programmed cell deathGO:0043069580.015
negative regulation of apoptotic processGO:0043066550.015
epithelial cell differentiationGO:00308551160.015
oocyte maturationGO:000155640.015
guanosine containing compound catabolic processGO:190106920.015
leukocyte proliferationGO:007066110.015
apoptotic processGO:00069151160.015
regulation of primary metabolic processGO:00800903110.015
regulation of multicellular organism growthGO:004001440.015
gtp metabolic processGO:004603940.015
stem cell maintenanceGO:001982740.015
catechol containing compound metabolic processGO:000971220.014
homeostatic processGO:00425921420.014
adult behaviorGO:003053420.014
growthGO:00400071740.014
regulation of macromolecule metabolic processGO:00602553170.014
regulation of metabolic processGO:00192223590.014
response to metal ionGO:0010038340.014
regulation of organ growthGO:004662030.013
neurological system processGO:0050877620.013
Mouse
cell motilityGO:00488702440.013
ear developmentGO:00435831270.013
protein modification by small protein conjugationGO:0032446130.013
establishment of localization in cellGO:0051649770.013
multicellular organismal response to stressGO:003355520.012
cellular catabolic processGO:0044248270.012
water homeostasisGO:003010440.012
negative regulation of cell deathGO:0060548600.012
regulation of phosphorylationGO:0042325260.012
kidney developmentGO:0001822920.012
reactive oxygen species biosynthetic processGO:190340910.012
cell projection organizationGO:00300302840.012
multicellular organism reproductionGO:0032504350.012
regulation of protein metabolic processGO:0051246560.012
positive regulation of secretion by cellGO:190353210.012
macromolecule localizationGO:0033036540.012
regulation of nitrogen compound metabolic processGO:00511712510.012
regulation of reproductive processGO:200024140.012
nucleocytoplasmic transportGO:000691340.012
purine nucleoside monophosphate catabolic processGO:000912840.011
cellular amine metabolic processGO:004410620.011
hepatocyte proliferationGO:007257420.011
removal of superoxide radicalsGO:001943020.011
cell agingGO:000756920.011
protein importGO:001703830.011
positive regulation of cellular metabolic processGO:0031325940.011
positive regulation of cell activationGO:005086710.011
system processGO:00030081850.011
Mouse
proteasomal protein catabolic processGO:001049820.011
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.011
cellular nitrogen compound metabolic processGO:00346412900.011
protein modification by small protein conjugation or removalGO:0070647140.011
cell surface receptor signaling pathwayGO:00071663250.011
regulation of cellular amine metabolic processGO:003323800.010
regulation of localizationGO:00328791040.010
response to oxygen radicalGO:000030520.010
cellular response to superoxideGO:007145120.010
cellular response to external stimulusGO:007149620.010
epidermis morphogenesisGO:004873040.010
lymphocyte proliferationGO:004665110.010
rna localizationGO:000640340.010
response to estrogenGO:0043627270.010
response to ethanolGO:004547160.010
phosphorus metabolic processGO:00067931090.010
otolith developmentGO:0048840320.010

manf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
musculoskeletal system diseaseDOID:1700.012
muscle tissue diseaseDOID:6600.010
muscular diseaseDOID:008000000.010
myopathyDOID:42300.010